Patrick M. Nolan - Publications

Affiliations: 
Medical Research Council Harwell, Didcot, England, United Kingdom 
Area:
Genetics
Website:
https://www.har.mrc.ac.uk/research/lifetime-studies/neurobehavioural-genetics

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Year Citation  Score
2017 Maggi S, Balzani E, Lassi G, Garcia-Garcia C, Plano A, Espinoza S, Mus L, Tinarelli F, Nolan PM, Gainetdinov RR, Balci F, Nieus T, Tucci V. The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis. Scientific Reports. 7: 17765. PMID 29259298 DOI: 10.1038/s41598-017-18130-2  0.48
2017 Moir L, Bochukova EG, Dumbell R, Banks G, Bains RS, Nolan PM, Scudamore C, Simon M, Watson KA, Keogh J, Henning E, Hendricks A, O'Rahilly S, Barroso I, et al. Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety. Molecular Metabolism. 6: 1419-1428. PMID 29107289 DOI: 10.1016/j.molmet.2017.08.006  0.32
2017 Wilcox AG, Vizor L, Parsons MJ, Banks G, Nolan PM. Inducible Knockout of Mouse Zfhx3 Emphasizes Its Key Role in Setting the Pace and Amplitude of the Adult Circadian Clock. Journal of Biological Rhythms. 748730417722631. PMID 28816086 DOI: 10.1177/0748730417722631  0.32
2016 Potter PK, Bowl MR, Jeyarajan P, Wisby L, Blease A, Goldsworthy ME, Simon MM, Greenaway S, Michel V, Barnard A, Aguilar C, Agnew T, Banks G, Blake A, Chessum L, ... ... Nolan PM, et al. Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nature Communications. 7: 12444. PMID 27534441 DOI: 10.1038/ncomms12444  0.32
2016 Bains RS, Cater HL, Sillito RR, Chartsias A, Sneddon D, Concas D, Keskivali-Bond P, Lukins TC, Wells S, Acevedo Arozena A, Nolan PM, Armstrong JD. Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System. Frontiers in Behavioral Neuroscience. 10: 106. PMID 27375446 DOI: 10.3389/fnbeh.2016.00106  0.32
2016 Balzani E, Lassi G, Maggi S, Sethi S, Parsons MJ, Simon M, Nolan PM, Tucci V. The Zfhx3-Mediated Axis Regulates Sleep and Interval Timing in Mice. Cell Reports. PMID 27373158 DOI: 10.1016/j.celrep.2016.06.017  0.32
2016 Pilorz V, Tam SK, Hughes S, Pothecary CA, Jagannath A, Hankins MW, Bannerman DM, Lightman SL, Vyazovskiy VV, Nolan PM, Foster RG, Peirson SN. Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light. Plos Biology. 14: e1002482. PMID 27276063 DOI: 10.1371/journal.pbio.1002482  0.32
2016 Madeo M, Stewart M, Sun Y, Sahir N, Wiethoff S, Chandrasekar I, Yarrow A, Rosenfeld JA, Yang Y, Cordeiro D, McCormick EM, Muraresku CC, Jepperson TN, McBeth LJ, Seidahmed MZ, ... ... Nolan PM, et al. Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy. American Journal of Human Genetics. PMID 27236917 DOI: 10.1016/j.ajhg.2016.04.008  0.32
2016 Banks G, Nolan PM, Peirson SN. Reciprocal interactions between circadian clocks and aging. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 27137838 DOI: 10.1007/s00335-016-9639-6  0.32
2016 Militi S, Maywood ES, Sandate CR, Chesham JE, Barnard AR, Parsons MJ, Vibert JL, Joynson GM, Partch CL, Hastings MH, Nolan PM. Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking. Proceedings of the National Academy of Sciences of the United States of America. PMID 26903623 DOI: 10.1073/pnas.1517549113  0.32
2015 Parsons MJ, Brancaccio M, Sethi S, Maywood ES, Satija R, Edwards JK, Jagannath A, Couch Y, Finelli MJ, Smyllie NJ, Esapa C, Butler R, Barnard AR, Chesham JE, Saito S, ... ... Nolan PM, et al. The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis. Cell. 162: 607-21. PMID 26232227 DOI: 10.1016/j.cell.2015.06.060  0.32
2015 de Angelis MH, Nicholson G, Selloum M, White JK, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, ... ... Nolan PM, et al. Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics. Nature Genetics. PMID 26214591 DOI: 10.1038/ng.3360  0.32
2015 Denis D, French CC, Rowe R, Zavos HM, Nolan PM, Parsons MJ, Gregory AM. A twin and molecular genetics study of sleep paralysis and associated factors. Journal of Sleep Research. PMID 25659590 DOI: 10.1111/jsr.12282  0.32
2015 Parsons MJ, Moffitt TE, Gregory AM, Goldman-Mellor S, Nolan PM, Poulton R, Caspi A. Social jetlag, obesity and metabolic disorder: investigation in a cohort study. International Journal of Obesity (2005). 39: 842-8. PMID 25601363 DOI: 10.1038/ijo.2014.201  0.32
2015 Heise I, Fisher SP, Banks GT, Wells S, Peirson SN, Foster RG, Nolan PM. Sleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndrome. Genes, Brain, and Behavior. 14: 209-16. PMID 25558895 DOI: 10.1111/gbb.12198  0.32
2015 Joyce PI, Mcgoldrick P, Saccon RA, Weber W, Fratta P, West SJ, Zhu N, Carter S, Phatak V, Stewart M, Simon M, Kumar S, Heise I, Bros-Facer V, Dick J, ... ... Nolan PM, et al. A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity. Human Molecular Genetics. 24: 1883-97. PMID 25468678 DOI: 10.1093/hmg/ddu605  0.32
2015 Banks G, Heise I, Starbuck B, Osborne T, Wisby L, Potter P, Jackson IJ, Foster RG, Peirson SN, Nolan PM. Genetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep. Neurobiology of Aging. 36: 380-93. PMID 25179226 DOI: 10.1016/j.neurobiolaging.2014.07.040  0.32
2014 Parsons MJ, Lester KJ, Barclay NL, Archer SN, Nolan PM, Eley TC, Gregory AM. Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures. Journal of Sleep Research. 23: 595-604. PMID 24635757 DOI: 10.1111/jsr.12144  0.32
2014 Tucci V, Kleefstra T, Hardy A, Heise I, Maggi S, Willemsen MH, Hilton H, Esapa C, Simon M, Buenavista MT, McGuffin LJ, Vizor L, Dodero L, Tsaftaris S, Romero R, ... ... Nolan PM, et al. Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features. The Journal of Clinical Investigation. 124: 1468-82. PMID 24614104 DOI: 10.1172/JCI70372  0.32
2014 Gallistel CR, Tucci V, Nolan PM, Schachner M, Jakovcevski I, Kheifets A, Barboza L. Cognitive assessment of mice strains heterozygous for cell-adhesion genes reveals strain-specific alterations in timing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20120464. PMID 24446498 DOI: 10.1098/rstb.2012.0464  0.32
2014 Mandillo S, Heise I, Garbugino L, Tocchini-Valentini GP, Giuliani A, Wells S, Nolan PM. Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation. Disease Models & Mechanisms. 7: 397-407. PMID 24423792 DOI: 10.1242/dmm.013946  0.32
2014 Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, et al. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular Psychiatry. 19: 88-98. PMID 23164821 DOI: 10.1038/mp.2012.163  0.32
2013 Parsons MJ, Lester KJ, Barclay NL, Nolan PM, Eley TC, Gregory AM. Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 431-8. PMID 23780892 DOI: 10.1002/ajmg.b.32106  0.32
2013 Anand SN, Maywood ES, Chesham JE, Joynson G, Banks GT, Hastings MH, Nolan PM. Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7145-53. PMID 23616524 DOI: 10.1523/JNEUROSCI.4950-12.2013  0.32
2012 Anand SN, Edwards JK, Nolan PM. Generation of mouse mutants as tools in dissecting the molecular clock. Progress in Brain Research. 199: 247-65. PMID 22877670 DOI: 10.1016/B978-0-444-59427-3.00015-0  0.32
2012 Keers R, Pedroso I, Breen G, Aitchison KJ, Nolan PM, Cichon S, Nöthen MM, Rietschel M, Schalkwyk LC, Fernandes C. Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours. Plos One. 7: e38263. PMID 22719873 DOI: 10.1371/journal.pone.0038263  0.32
2012 Smith LB, Milne L, Nelson N, Eddie S, Brown P, Atanassova N, O'Bryan MK, O'Donnell L, Rhodes D, Wells S, Napper D, Nolan P, Lalanne Z, Cheeseman M, Peters J. KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility. Plos Genetics. 8: e1002697. PMID 22654668 DOI: 10.1371/journal.pgen.1002697  0.32
2011 Maywood ES, Chesham JE, Meng QJ, Nolan PM, Loudon AS, Hastings MH. Tuning the period of the mammalian circadian clock: additive and independent effects of CK1εTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1539-44. PMID 21273438 DOI: 10.1523/JNEUROSCI.4107-10.2011  0.32
2011 Fossat N, Jones V, Khoo PL, Bogani D, Hardy A, Steiner K, Mukhopadhyay M, Westphal H, Nolan PM, Arkell R, Tam PP. Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo. Development (Cambridge, England). 138: 667-76. PMID 21228006 DOI: 10.1242/dev.052803  0.32
2010 Church C, Moir L, McMurray F, Girard C, Banks GT, Teboul L, Wells S, Brüning JC, Nolan PM, Ashcroft FM, Cox RD. Overexpression of Fto leads to increased food intake and results in obesity. Nature Genetics. 42: 1086-92. PMID 21076408 DOI: 10.1038/ng.713  0.32
2010 Mandillo S, Tucci V, Hölter SM, Meziane H, Al Banchaabouchi M, Kallnik M, Lad HV, Nolan PM, Ouagazzal AM, Coghill EL, Gale K, Golini E, Jacquot S, Krezel W, Parker A, et al. Reliability, robustness, and reproducibility in mouse behavioral phenotyping: A cross-laboratory study (Physiological Genomics (2008) 34, (243-255) DOI: 10.1152/physiolgenomics.90207.2008) Physiological Genomics. 40: 2117. DOI: 10.1152/physiolgenomics.zh7-3430-corr.2010  0.32
2009 Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, ... ... Nolan PM, et al. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms. 2: 359-73. PMID 19470612 DOI: 10.1242/dmm.002527  0.32
2009 Becker EB, Oliver PL, Glitsch MD, Banks GT, Achilli F, Hardy A, Nolan PM, Fisher EM, Davies KE. A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 6706-11. PMID 19351902 DOI: 10.1073/pnas.0810599106  0.32
2009 Nolan PM, Parsons MJ. Clocks go forward: progress in the molecular genetic analysis of rhythmic behaviour. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 67-70. PMID 19145460 DOI: 10.1007/s00335-008-9166-1  0.32
2009 Tucci V, Nolan PM. Toward an understanding of the function of sleep: New insights from mouse genetics Evolution of Sleep: Phylogenetic and Functional Perspectives. 12-33. DOI: 10.1017/CBO9780511642074.011  0.32
2008 Barnard AR, Nolan PM. When clocks go bad: neurobehavioural consequences of disrupted circadian timing. Plos Genetics. 4: e1000040. PMID 18516223 DOI: 10.1371/journal.pgen.1000040  0.32
2008 Mandillo S, Tucci V, Hölter SM, Meziane H, Banchaabouchi MA, Kallnik M, Lad HV, Nolan PM, Ouagazzal AM, Coghill EL, Gale K, Golini E, Jacquot S, Krezel W, Parker A, et al. Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiological Genomics. 34: 243-55. PMID 18505770 DOI: 10.1152/physiolgenomics.90207.2008  0.32
2008 Groszer M, Keays DA, Deacon RM, de Bono JP, Prasad-Mulcare S, Gaub S, Baum MG, French CA, Nicod J, Coventry JA, Enard W, Fray M, Brown SD, Nolan PM, Pääbo S, et al. Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits. Current Biology : Cb. 18: 354-62. PMID 18328704 DOI: 10.1016/j.cub.2008.01.060  0.32
2007 Maywood ES, O'Neill JS, Reddy AB, Chesham JE, Prosser HM, Kyriacou CP, Godinho SI, Nolan PM, Hastings MH. Genetic and molecular analysis of the central and peripheral circadian clockwork of mice. Cold Spring Harbor Symposia On Quantitative Biology. 72: 85-94. PMID 18419265 DOI: 10.1101/sqb.2007.72.005  0.32
2007 Tucci V, Achilli F, Blanco G, Lad HV, Wells S, Godinho S, Nolan PM. Reaching and grasping phenotypes in the mouse (Mus musculus): a characterization of inbred strains and mutant lines. Neuroscience. 147: 573-82. PMID 17574766 DOI: 10.1016/j.neuroscience.2007.04.034  0.32
2007 Hough TA, Polewski M, Johnson K, Cheeseman M, Nolan PM, Vizor L, Rastan S, Boyde A, Pritzker K, Hunter AJ, Fisher EM, Terkeltaub R, Brown SD. Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1397-407. PMID 17539739 DOI: 10.1359/jbmr.070515  0.32
2007 Muers MR, Sharpe JA, Garrick D, Sloane-Stanley J, Nolan PM, Hacker T, Wood WG, Higgs DR, Gibbons RJ. Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse model. American Journal of Human Genetics. 80: 1138-49. PMID 17503331 DOI: 10.1086/518369  0.32
2007 Godinho SI, Maywood ES, Shaw L, Tucci V, Barnard AR, Busino L, Pagano M, Kendall R, Quwailid MM, Romero MR, O'neill J, Chesham JE, Brooker D, Lalanne Z, Hastings MH, ... Nolan PM, et al. The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science (New York, N.Y.). 316: 897-900. PMID 17463252 DOI: 10.1126/science.1141138  0.32
2007 Busino L, Bassermann F, Maiolica A, Lee C, Nolan PM, Godinho SI, Draetta GF, Pagano M. SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science (New York, N.Y.). 316: 900-4. PMID 17463251 DOI: 10.1126/science.1141194  0.32
2007 Keays DA, Tian G, Poirier K, Huang GJ, Siebold C, Cleak J, Oliver PL, Fray M, Harvey RJ, Molnár Z, Piñon MC, Dear N, Valdar W, Brown SD, Davies KE, ... ... Nolan P, et al. Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell. 128: 45-57. PMID 17218254 DOI: 10.1016/j.cell.2006.12.017  0.32
2006 Tucci V, Lad HV, Parker A, Polley S, Brown SD, Nolan PM. Gene-environment interactions differentially affect mouse strain behavioral parameters. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 1113-20. PMID 17091318 DOI: 10.1007/s00335-006-0075-x  0.32
2006 Tucci V, Hardy A, Nolan PM. A comparison of physiological and behavioural parameters in C57BL/6J mice undergoing food or water restriction regimes. Behavioural Brain Research. 173: 22-9. PMID 16870275 DOI: 10.1016/j.bbr.2006.05.031  0.32
2006 Godinho SI, Nolan PM. The role of mutagenesis in defining genes in behaviour. European Journal of Human Genetics : Ejhg. 14: 651-9. PMID 16721401 DOI: 10.1038/sj.ejhg.5201545  0.32
2006 Anjum S, Bogacz R, Tucci V, Nolan PM. Model of reinforcement learning in the mouse reaching and grasping experiment Proceedings of Aisb'06: Adaptation in Artificial and Biological Systems. 1: 30-36.  0.32
2005 Bogani D, Willoughby C, Davies J, Kaur K, Mirza G, Paudyal A, Haines H, McKeone R, Cadman M, Pieles G, Schneider JE, Bhattacharya S, Hardy A, Nolan PM, Tripodis N, et al. Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen. Proceedings of the National Academy of Sciences of the United States of America. 102: 12477-82. PMID 16109771 DOI: 10.1073/pnas.0500584102  0.32
2005 Lunny DP, Weed E, Nolan PM, Marquardt A, Augustin M, Porter RM. Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland. The Journal of Investigative Dermatology. 124: 615-21. PMID 15737203 DOI: 10.1111/j.0022-202X.2005.23623.x  0.32
2004 Tsipouri V, Curtin JA, Nolan PM, Vizor L, Parsons CA, Clapham CM, Latham ID, Rooke LJ, Martin JE, Peters J, Hunter AJ, Rogers D, Rastan S, Brown SD, Fisher EM, et al. Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouse. Comparative and Functional Genomics. 5: 123-7. PMID 18629060 DOI: 10.1002/cfg.382  0.32
2004 Rastan S, Hough T, Kierman A, Hardisty R, Erven A, Gray IC, Voeling S, Isaacs A, Tsai H, Strivens M, Washbourne R, Thornton C, Greenaway S, Hewitt M, McCormick S, ... ... Nolan PM, et al. Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders. Genetica. 122: 47-9. PMID 15619960 DOI: 10.1007/s10709-004-1930-x  0.32
2004 Bogani D, Warr N, Elms P, Davies J, Tymowska-Lalanne Z, Goldsworthy M, Cox RD, Keays DA, Flint J, Wilson V, Nolan P, Arkell R. New semidominant mutations that affect mouse development Genesis. 40: 109-117. PMID 15384171 DOI: 10.1002/gene.20071  0.32
2004 Bacon Y, Ooi A, Kerr S, Shaw-Andrews L, Winchester L, Breeds S, Tymoska-Lalanne Z, Clay J, Greenfield AG, Nolan PM. Screening for novel ENU-induced rhythm, entrainment and activity mutants. Genes, Brain, and Behavior. 3: 196-205. PMID 15248865 DOI: 10.1111/j.1601-183X.2004.00070.x  0.32
2003 Keays DA, Nolan PM. N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders. European Journal of Pharmacology. 480: 205-17. PMID 14623363 DOI: 10.1016/j.ejphar.2003.08.107  0.32
2003 Curtin JA, Quint E, Tsipouri V, Arkell RM, Cattanach B, Copp AJ, Henderson DJ, Spurr N, Stanier P, Fisher EM, Nolan PM, Steel KP, Brown SD, Gray IC, Murdoch JN. Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Current Biology : Cb. 13: 1129-33. PMID 12842012 DOI: 10.1016/S0960-9822(03)00374-9  0.32
2003 Isaacs AM, Oliver PL, Jones EL, Jeans A, Potter A, Hovik BH, Nolan PM, Vizor L, Glenister P, Simon AK, Gray IC, Spurr NK, Brown SD, Hunter AJ, Davies KE. A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1631-7. PMID 12629167  0.32
2002 Nolan PM, Hugill A, Cox RD. ENU mutagenesis in the mouse: application to human genetic disease. Briefings in Functional Genomics & Proteomics. 1: 278-89. PMID 15239894 DOI: 10.1093/bfgp/1.3.278  0.32
2002 Hough TA, Nolan PM, Tsipouri V, Toye AA, Gray IC, Goldsworthy M, Moir L, Cox RD, Clements S, Glenister PH, Wood J, Selley RL, Strivens MA, Vizor L, McCormack SL, et al. Novel phenotypes identified by plasma biochemical screening in the mouse. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 595-602. PMID 12420138 DOI: 10.1007/s00335-002-2188-1  0.32
2002 Kapfhamer D, Valladares O, Sun Y, Nolan PM, Rux JJ, Arnold SE, Veasey SC, Bu?an M. Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse. Nature Genetics. 32: 290-5. PMID 12244319 DOI: 10.1038/ng991  0.32
2002 Thaung C, West K, Clark BJ, McKie L, Morgan JE, Arnold K, Nolan PM, Peters J, Hunter AJ, Brown SD, Jackson IJ, Cross SH. Novel ENU-induced eye mutations in the mouse: models for human eye disease. Human Molecular Genetics. 11: 755-67. PMID 11929848  0.32
2002 Kiernan AE, Erven A, Voegeling S, Peters J, Nolan P, Hunter J, Bacon Y, Steel KP, Brown SDM, Guénet JL. ENU mutagenesis reveals a highly mutable locus on mouse Chromosome 4 that affects ear morphogenesis Mammalian Genome. 13: 142-148. PMID 11919684 DOI: 10.1007/s0033501-2088-9  0.32
2002 Hara H, Nolan PM, Scott MO, Bucan M, Wakayama Y, Fischbeck KH. Running endurance abnormality in mdx mice. Muscle & Nerve. 25: 207-11. PMID 11870688 DOI: 10.1002/mus.10023  0.32
2002 Thaung C, Hough T, Hunter AJ, Hardisty R, Nolan PM. In search of new disease models in the mouse using ENU mutagenesis. Ernst Schering Research Foundation Workshop. 109-34. PMID 11859561  0.32
2001 Alavizadeh A, Kiernan AE, Nolan P, Lo C, Steel KP, Bucan M. The Wheels mutation in the mouse causes vascular, hindbrain, and inner ear defects Developmental Biology. 234: 244-260. PMID 11356033 DOI: 10.1006/dbio.2001.0241  0.32
2000 Nolan PM. Generation of mouse mutants as a tool for functional genomics. Pharmacogenomics. 1: 243-55. PMID 11256576 DOI: 10.1517/14622416.1.3.243  0.32
2000 Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, et al. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nature Genetics. 25: 440-3. PMID 10932191 DOI: 10.1038/78140  0.32
2000 Isaacs AM, Davies KE, Hunter AJ, Nolan PM, Vizor L, Peters J, Gale DG, Kelsell DP, Latham ID, Chase JM, Fisher EM, Bouzyk MM, Potter A, Masih M, Walsh FS, et al. Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy. Human Molecular Genetics. 9: 1865-71. PMID 10915775  0.32
2000 Strivens MA, Selley RL, Greenaway SJ, Hewitt M, Liu X, Battershill K, McCormack SL, Pickford KA, Vizor L, Nolan PM, Hunter AJ, Peters J, Brown SD. Informatics for mutagenesis: the design of mutabase--a distributed data recording system for animal husbandry, mutagenesis, and phenotypic analysis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 577-83. PMID 10886026 DOI: 10.1007/s003350010110  0.32
2000 Nolan PM, Peters J, Vizor L, Strivens M, Washbourne R, Hough T, Wells C, Glenister P, Thornton C, Martin J, Fisher E, Rogers D, Hagan J, Reavill C, Gray I, et al. Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 500-6. PMID 10886012 DOI: 10.1007/s003350010096  0.32
2000 Hunter AJ, Nolan PM, Brown SD. Towards new models of disease and physiology in the neurosciences: the role of induced and naturally occurring mutations. Human Molecular Genetics. 9: 893-900. PMID 10767312  0.32
1999 Couldrey C, Carlton MB, Nolan PM, Colledge WH, Evans MJ. A retroviral gene trap insertion into the histone 3.3A gene causes partial neonatal lethality, stunted growth, neuromuscular deficits and male sub-fertility in transgenic mice. Human Molecular Genetics. 8: 2489-95. PMID 10556297  0.32
1998 Brown SD, Nolan PM. Mouse mutagenesis-systematic studies of mammalian gene function. Human Molecular Genetics. 7: 1627-33. PMID 9735384 DOI: 10.1093/hmg/7.10.1627  0.32
1997 Nolan PM, Kapfhamer D, Bu?an M. Random mutagenesis screen for dominant behavioral mutations in mice. Methods (San Diego, Calif.). 13: 379-95. PMID 9480783 DOI: 10.1006/meth.1997.0545  0.32
1995 Pickard GE, Sollars PJ, Rinchik EM, Nolan PM, Bucan M. Mutagenesis and behavioral screening for altered circadian activity identifies the mouse mutant, Wheels. Brain Research. 705: 255-66. PMID 8821757 DOI: 10.1016/0006-8993(95)01171-4  0.32
1995 Gafvels ME, Paavola LG, Boyd CO, Nolan PM, Wittmaack F, Chawla A, Lazar MA, Bucan M, Angelin B, Strauss JF. Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19". Endocrinology. 136: 795. PMID 7835312 DOI: 10.1210/endo.136.2.7835312  0.32
1995 Nolan PM, Sollars PJ, Bohne BA, Ewens WJ, Pickard GE, Bu?an M. Heterozygosity mapping of partially congenic lines: mapping of a semidominant neurological mutation, Wheels (Whl), on mouse chromosome 4. Genetics. 140: 245-54. PMID 7635289  0.32
1994 Gåfvels ME, Paavola LG, Boyd CO, Nolan PM, Wittmaack F, Chawla A, Lazar MA, Bucan M, Angelin BO, Strauss JF. Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19. Endocrinology. 135: 387-94. PMID 8013374 DOI: 10.1210/endo.135.1.8013374  0.32
1993 Bućan M, Gatalica B, Nolan P, Chung A, Leroux A, Grossman MH, Nadeau JH, Emanuel BS, Budarf M. Comparative mapping of 9 human chromosome 22q loci in the laboratory mouse Human Molecular Genetics. 2: 1245-1252. PMID 8401507  0.32
1992 Doyle E, Nolan PM, Bell R, Regan CM. Hippocampal NCAM180 transiently increases sialylation during the acquisition and consolidation of a passive avoidance response in the adult rat. Journal of Neuroscience Research. 31: 513-23. PMID 1640502 DOI: 10.1002/jnr.490310315  0.32
1992 Doyle E, Nolan PM, Bell R, Regan CM. Intraventricular infusions of anti-neural cell adhesion molecules in a discrete posttraining period impair consolidation of a passive avoidance response in the rat. Journal of Neurochemistry. 59: 1570-3. PMID 1402906  0.32
1992 Shashoua VE, Nolan PM, Shea TB, Milinazzo B. Dibutyryl cyclic AMP stimulates expression of ependymin mRNA and the synthesis and release of the protein into the culture medium by neuroblastoma cells (NB2a/d1). Journal of Neuroscience Research. 32: 239-44. PMID 1328662 DOI: 10.1002/jnr.490320213  0.32
1992 Doyle E, Nolan P, Bell R, Regan CM. Neurodevelopmental events underlying information acquisition and storage Network: Computation in Neural Systems. 3: 89-94. DOI: 10.1088/0954-898X_3_1_010  0.32
1990 Doyle E, Nolan PM, Regan CM. Learning-induced change in neural activity during acquisition and consolidation of a passive avoidance response in the rat. Neurochemical Research. 15: 551-8. PMID 2370948 DOI: 10.1007/BF00966216  0.32
1988 Breen KC, Nolan PM, Regan CM. Soluble rat brain sialidase does not influence intracellular glycosylation of Golgi sialyltransferase or its constitutive glycoproteins. Neuroscience Letters. 88: 308-12. PMID 3386877 DOI: 10.1016/0304-3940(88)90229-7  0.32
1987 Nolan PM, Bell R, Regan CM. Acquisition of a brief behavioural experience in the rat is inhibited by the brain-specific monoclonal antibody, F3-87-8. Neuroscience Letters. 79: 346-50. PMID 3658225 DOI: 10.1016/0304-3940(87)90457-5  0.32
1987 Nolan PM, Bell R, Regan CM. Acquisition of a brief behavioral experience in the presence of neuron-specific and D2-CAM/N-CAM-specific antisera. Neurochemical Research. 12: 619-24. PMID 3614512 DOI: 10.1007/BF00971010  0.32
1985 Nolan PM, Phelan PP, Regan CM. The effect of sodium valproate on brain glutaminase and glutamine synthetase Ircs Medical Science. 13: 873-874.  0.32
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