| Year |
Citation |
Score |
| 2024 |
Dafinca R, Tosat-Bitrian C, Carroll E, Vahsen BF, Gilbert-Jaramillo J, Scaber J, Feneberg E, Johnson E, Talbot K. Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neurons. Brain Communications. 6: fcae350. PMID 39440303 DOI: 10.1093/braincomms/fcae350 |
0.389 |
|
| 2024 |
Pérez de la Lastra Aranda C, Tosat-Bitrián C, Porras G, Dafinca R, Muñoz-Torrero D, Talbot K, Martín-Requero Á, Martínez A, Palomo V. Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation. Acs Chemical Neuroscience. PMID 39401249 DOI: 10.1021/acschemneuro.4c00328 |
0.3 |
|
| 2024 |
Vieira de Sá R, Sudria-Lopez E, Cañizares Luna M, Harschnitz O, van den Heuvel DMA, Kling S, Vonk D, Westeneng HJ, Karst H, Bloemenkamp L, Varderidou-Minasian S, Schlegel DK, Mars M, Broekhoven MH, van Kronenburg NCH, ... ... Talbot K, et al. ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes. Nature Communications. 15: 7484. PMID 39209824 DOI: 10.1038/s41467-024-51676-0 |
0.409 |
|
| 2024 |
Scaber J, Thomas-Wright I, Clark AJ, Xu Y, Vahsen BF, Carcolé M, Dafinca R, Farrimond L, Isaacs AM, Bennett DL, Talbot K. Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons. Stem Cell Reports. PMID 38876108 DOI: 10.1016/j.stemcr.2024.05.008 |
0.386 |
|
| 2024 |
Nikel LM, Talbot K, Vahsen BF. Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2400054. PMID 38713169 DOI: 10.1002/bies.202400054 |
0.418 |
|
| 2023 |
Vahsen BF, Nalluru S, Morgan GR, Farrimond L, Carroll E, Xu Y, Cramb KML, Amein B, Scaber J, Katsikoudi A, Candalija A, Carcolé M, Dafinca R, Isaacs AM, Wade-Martins R, ... ... Talbot K, et al. C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9. Nature Communications. 14: 5898. PMID 37736756 DOI: 10.1038/s41467-023-41603-0 |
0.37 |
|
| 2023 |
Christoforidou E, Simoes FA, Gordon D, Talbot K, Hafezparast M. Aberrant dynein function promotes TDP-43 aggregation and upregulation of p62 in male mice harboring transgenic human TDP-43. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-10. PMID 37498094 DOI: 10.1080/21678421.2023.2239276 |
0.407 |
|
| 2022 |
Chaytow H, Carroll E, Gordon D, Huang YT, van der Hoorn D, Smith HL, Becker T, Becker CG, Faller KME, Talbot K, Gillingwater TH. Targeting phosphoglycerate kinase 1 with terazosin improves motor neuron phenotypes in multiple models of amyotrophic lateral sclerosis. Ebiomedicine. 104202. PMID 35963713 DOI: 10.1016/j.ebiom.2022.104202 |
0.363 |
|
| 2022 |
Cooper-Knock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T, Shelkovnikova T, Castelli L, Hautbergue GM, Hewitt C, Kirby J, et al. Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP. Brain Pathology (Zurich, Switzerland). e13104. PMID 35871544 DOI: 10.1111/bpa.13104 |
0.417 |
|
| 2022 |
Vahsen BF, Gray E, Candalija A, Cramb KML, Scaber J, Dafinca R, Katsikoudi A, Xu Y, Farrimond L, Wade-Martins R, James WS, Turner MR, Cowley SA, Talbot K. Human iPSC co-culture model to investigate the interaction between microglia and motor neurons. Scientific Reports. 12: 12606. PMID 35871163 DOI: 10.1038/s41598-022-16896-8 |
0.394 |
|
| 2022 |
Pandya S, Maia PD, Freeze B, Menke RAL, Talbot K, Turner MR, Raj A. Modeling seeding and neuroanatomic spread of pathology in amyotrophic lateral sclerosis. Neuroimage. 251: 118968. PMID 35143975 DOI: 10.1016/j.neuroimage.2022.118968 |
0.329 |
|
| 2022 |
Dharmadasa T, Scaber J, Edmond E, Marsden R, Thompson A, Talbot K, Turner MR. Genetic testing in motor neurone disease. Practical Neurology. PMID 35027459 DOI: 10.1136/practneurol-2021-002989 |
0.364 |
|
| 2022 |
Giacomelli E, Vahsen BF, Calder EL, Xu Y, Scaber J, Gray E, Dafinca R, Talbot K, Studer L. Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation. Cell Stem Cell. 29: 11-35. PMID 34995492 DOI: 10.1016/j.stem.2021.12.008 |
0.314 |
|
| 2021 |
Johnson JO, Chia R, Miller DE, Li R, Kumaran R, Abramzon Y, Alahmady N, Renton AE, Topp SD, Gibbs JR, Cookson MR, Sabir MS, Dalgard CL, Troakes C, Jones AR, ... ... Talbot K, et al. Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis. Jama Neurology. PMID 34459874 DOI: 10.1001/jamaneurol.2021.2598 |
0.612 |
|
| 2021 |
Vahsen BF, Gray E, Thompson AG, Ansorge O, Anthony DC, Cowley SA, Talbot K, Turner MR. Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers. Nature Reviews. Neurology. PMID 33927394 DOI: 10.1038/s41582-021-00487-8 |
0.34 |
|
| 2020 |
Feneberg E, Charles PD, Finelli MJ, Scott C, Kessler BM, Fischer R, Ansorge O, Gray E, Talbot K, Turner MR. Detection and Quantification of Novel C-terminal TDP-43 Fragments in ALS-TDP. Brain Pathology (Zurich, Switzerland). e12923. PMID 33300249 DOI: 10.1111/bpa.12923 |
0.709 |
|
| 2020 |
Herrando-Grabulosa M, Casas C, Talbot K, Aguilera J. Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease. Toxins. 12. PMID 33096857 DOI: 10.3390/toxins12100666 |
0.326 |
|
| 2020 |
Opie-Martin S, Ossher L, Bredin A, Kulka A, Pearce N, Talbot K, Al-Chalabi A. Motor Neuron Disease Register for England, Wales and Northern Ireland-an analysis of incidence in England. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 32940088 DOI: 10.1080/21678421.2020.1812661 |
0.3 |
|
| 2020 |
Sathyaprakash C, Manzano R, Varela MA, Hashimoto Y, Wood MJA, Talbot K, Aoki Y. Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion. Methods in Molecular Biology (Clifton, N.J.). 2176: 185-208. PMID 32865792 DOI: 10.1007/978-1-0716-0771-8_14 |
0.502 |
|
| 2020 |
Thompson AG, Gray E, Mäger I, Thézénas ML, Charles PD, Talbot K, Fischer R, Kessler BM, Wood M, Turner MR. CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis. Clinical Proteomics. 17: 31. PMID 32821252 DOI: 10.1186/S12014-020-09294-7 |
0.384 |
|
| 2020 |
Feneberg E, Gordon D, Thompson AG, Finelli MJ, Dafinca R, Candalija A, Charles PD, Mäger I, Wood MJ, Fischer R, Kessler BM, Gray E, Turner MR, Talbot K. An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress. Neurobiology of Disease. 105050. PMID 32800996 DOI: 10.1016/J.Nbd.2020.105050 |
0.795 |
|
| 2020 |
Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus J, Shi J, Heckman M, Spiegel M, Cook C, Song Y, Yue M, Daughrity L, Carlomagno Y, Jansen-West K, ... ... Talbot K, et al. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. The Journal of Clinical Investigation. PMID 32790644 DOI: 10.1172/Jci139741 |
0.383 |
|
| 2020 |
Feneberg E, Turner MR, Ansorge O, Talbot K. Amyotrophic lateral sclerosis with a heterozygous D91A SOD1 variant and classical ALS-TDP neuropathology. Neurology. PMID 32769137 DOI: 10.1212/Wnl.0000000000010587 |
0.377 |
|
| 2020 |
Gray E, Thompson AG, Wuu J, Pelt J, Talbot K, Benatar M, Turner MR. CSF chitinases before and after symptom onset in amyotrophic lateral sclerosis. Annals of Clinical and Translational Neurology. PMID 32666680 DOI: 10.1002/Acn3.51114 |
0.342 |
|
| 2020 |
Talbot K. Amyotrophic Lateral Sclerosis: network vulnerability and monosynaptic connections. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 32665325 DOI: 10.1136/Jnnp-2020-323729 |
0.464 |
|
| 2020 |
Nolan M, Scott C, Gamarallage MP, Lunn D, Carpenter K, McDonough E, Meyer D, Kaanumalle S, Santamaria-Pang A, Turner MR, Talbot K, Ansorge O. Quantitative patterns of motor cortex proteinopathy across ALS genotypes. Acta Neuropathologica Communications. 8: 98. PMID 32616036 DOI: 10.1186/S40478-020-00961-2 |
0.49 |
|
| 2020 |
Kelly M, Lavrov A, Garcia-Gancedo L, Parr J, Hart R, Chiwera T, Shaw CE, Al-Chalabi A, Marsden R, Turner MR, Talbot K. The use of biotelemetry to explore disease progression markers in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 32573278 DOI: 10.1080/21678421.2020.1773501 |
0.338 |
|
| 2020 |
Ababneh NA, Scaber J, Flynn R, Douglas A, Barbagallo P, Candalija A, Turner MR, Sims D, Dafinca R, Cowley SA, Talbot K. Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair. Human Molecular Genetics. PMID 32504093 DOI: 10.1093/Hmg/Ddaa106 |
0.472 |
|
| 2020 |
Dafinca R, Barbagallo P, Farrimond L, Candalija A, Scaber J, Ababneh NA, Sathyaprakash C, Vowles J, Cowley SA, Talbot K. Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD. Stem Cell Reports. PMID 32330447 DOI: 10.1016/J.Stemcr.2020.03.023 |
0.391 |
|
| 2020 |
Turner MR, Talbot K. Primary lateral sclerosis: diagnosis and management. Practical Neurology. PMID 32217663 DOI: 10.1136/Practneurol-2019-002300 |
0.462 |
|
| 2020 |
Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G. Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes. Cell Reports. 30: 3655-3662.e2. PMID 32187538 DOI: 10.1016/J.Celrep.2020.02.078 |
0.813 |
|
| 2020 |
Tu S, Wang C, Menke RAL, Talbot K, Barnett M, Kiernan MC, Turner MR. Regional callosal integrity and bilaterality of limb weakness in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-7. PMID 32106716 DOI: 10.1080/21678421.2020.1733020 |
0.363 |
|
| 2020 |
Carling PJ, Mortiboys H, Green C, Mihaylov S, Sandor C, Schwartzentruber A, Taylor R, Wei W, Hastings C, Wong S, Lo C, Evetts S, Clemmens H, Wyles M, Willcox S, ... ... Talbot K, et al. Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's disease. Progress in Neurobiology. 101772. PMID 32058042 DOI: 10.1016/J.Pneurobio.2020.101772 |
0.35 |
|
| 2019 |
Oprişoreanu AM, Smith HL, Arya S, Webster R, Zhong Z, Wehner D, Cardozo MJ, Becker T, Talbot K, Becker CG. Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Reports. 29: 1082-1098.e10. PMID 31665626 DOI: 10.1016/J.Celrep.2019.09.033 |
0.386 |
|
| 2019 |
Williamson MG, Finelli MJ, Sleigh JN, Reddington A, Gordon D, Talbot K, Davies KE, Oliver PL. Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Human Molecular Genetics. PMID 31642482 DOI: 10.1093/Hmg/Ddz190 |
0.818 |
|
| 2019 |
Turner MR, Faull C, McDermott CJ, Nickol AH, Palmer J, Talbot K. Tracheostomy in motor neurone disease. Practical Neurology. PMID 31273080 DOI: 10.1136/Practneurol-2018-002109 |
0.432 |
|
| 2019 |
Thompson AG, Gray E, Bampton A, Raciborska D, Talbot K, Turner MR. CSF chitinase proteins in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31123140 DOI: 10.1136/Jnnp-2019-320442 |
0.32 |
|
| 2019 |
Young CA, Ealing J, McDermott C, Williams T, Al-Chalabi A, Majeed T, Burke G, Pinto A, Dick D, Talbot K, Harrower T, Walsh J, Chandran S, Hanemann CO, Mills R, et al. The relationships between symptoms, disability, perceived health and quality of life in amyotrophic lateral sclerosis/motor neuron disease. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 31116037 DOI: 10.1080/21678421.2019.1615951 |
0.346 |
|
| 2019 |
Allen SP, Hall B, Castelli LM, Francis L, Woof R, Siskos AP, Kouloura E, Gray E, Thompson AG, Talbot K, Higginbottom A, Myszczynska M, Allen CF, Stopford MJ, Hemingway J, et al. Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 30698736 DOI: 10.1093/Brain/Awy353 |
0.416 |
|
| 2019 |
Tu S, Menke RAL, Talbot K, Kiernan MC, Turner MR. Cerebellar tract alterations in PLS and ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-4. PMID 30663900 DOI: 10.1080/21678421.2018.1562554 |
0.447 |
|
| 2019 |
Robertson J, Gray E, Thompson A, Feneberg E, Talbot K, Turner M. 004 A triaging blood test for neurology? Serum neurofilament levels in a cohort of GP referrals Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.38 |
0.354 |
|
| 2019 |
Edmond EC, Menke R, Proudfoot M, Talbot K, Stagg CJ, Turner MR. Motor System Biomarkers In Amyotrophic Lateral Sclerosis Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.213 |
0.404 |
|
| 2018 |
Gordon D, Dafinca R, Scaber J, Alegre-Abarrategui J, Farrimond L, Scott C, Biggs D, Kent L, Oliver PL, Davies B, Ansorge O, Wade-Martins R, Talbot K. Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction. Neurobiology of Disease. PMID 30290270 DOI: 10.1016/J.Nbd.2018.09.024 |
0.75 |
|
| 2018 |
Wong MMK, Hoekstra SD, Vowles J, Watson LM, Fuller G, Németh AH, Cowley SA, Ansorge O, Talbot K, Becker EBE. Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation. Acta Neuropathologica Communications. 6: 99. PMID 30249303 DOI: 10.1186/S40478-018-0600-7 |
0.404 |
|
| 2018 |
Talbot K, Feneberg E, Scaber J, Thompson AG, Turner MR. Amyotrophic lateral sclerosis: the complex path to precision medicine. Journal of Neurology. PMID 30054789 DOI: 10.1007/S00415-018-8983-8 |
0.45 |
|
| 2018 |
Tu S, Menke RAL, Talbot K, Kiernan MC, Turner MR. Regional thalamic MRI as a marker of widespread cortical pathology and progressive frontotemporal involvement in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 30049750 DOI: 10.1136/Jnnp-2018-318625 |
0.346 |
|
| 2018 |
de Majo M, Topp SD, Smith BN, Nishimura AL, Chen HJ, Gkazi AS, Miller J, Wong CH, Vance C, Baas F, Ten Asbroek ALMA, Kenna KP, Ticozzi N, Redondo AG, Esteban-Pérez J, ... ... Talbot K, et al. ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function. Neurobiology of Aging. PMID 30033073 DOI: 10.1016/J.Neurobiolaging.2018.06.015 |
0.357 |
|
| 2018 |
Salter M, Corfield E, Ramadass A, Grand F, Green J, Westra J, Lim CR, Farrimond L, Feneberg E, Scaber J, Thompson A, Ossher L, Turner M, Talbot K, Cudkowicz M, et al. Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis. Ebiomedicine. PMID 29941342 DOI: 10.1016/J.Ebiom.2018.06.015 |
0.368 |
|
| 2018 |
Proudfoot M, van Ede F, Quinn A, Colclough GL, Wuu J, Talbot K, Benatar M, Woolrich MW, Nobre AC, Turner MR. Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. PMID 29678369 DOI: 10.1016/J.Clinph.2018.03.019 |
0.346 |
|
| 2018 |
Proudfoot M, Colclough GL, Quinn A, Wuu J, Talbot K, Benatar M, Nobre AC, Woolrich MW, Turner MR. Increased cerebral functional connectivity in ALS: A resting-state magnetoencephalography study. Neurology. 90: e1418-e1424. PMID 29661904 DOI: 10.1212/Wnl.0000000000005333 |
0.337 |
|
| 2018 |
Westeneng HJ, Debray TPA, Visser AE, van Eijk RPA, Rooney JPK, Calvo A, Martin S, McDermott CJ, Thompson AG, Pinto S, Kobeleva X, Rosenbohm A, Stubendorff B, Sommer H, Middelkoop BM, ... ... Talbot K, et al. Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model. The Lancet. Neurology. PMID 29598923 DOI: 10.1016/S1474-4422(18)30089-9 |
0.4 |
|
| 2018 |
Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Talbot K, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027 |
0.692 |
|
| 2018 |
Milinis K, Tennant A, Mills RJ, Al-Chalabi A, Burke G, Dick DJ, Ealing J, Hanemann CO, Harrower T, McDermott CJ, Majeed T, Pinto A, Talbot K, Williams T, Young CA, et al. Development and validation of Spasticity Index-Amyotrophic Lateral Sclerosis. Acta Neurologica Scandinavica. PMID 29468643 DOI: 10.1111/Ane.12910 |
0.347 |
|
| 2018 |
Feneberg E, Gray E, Ansorge O, Talbot K, Turner MR. Towards a TDP-43-Based Biomarker for ALS and FTLD. Molecular Neurobiology. PMID 29460270 DOI: 10.1007/S12035-018-0947-6 |
0.444 |
|
| 2018 |
Groen EJN, Talbot K, Gillingwater TH. Advances in therapy for spinal muscular atrophy: promises and challenges. Nature Reviews. Neurology. PMID 29422644 DOI: 10.1038/Nrneurol.2018.4 |
0.486 |
|
| 2018 |
Benoy V, Van Helleputte L, Prior R, d'Ydewalle C, Haeck W, Geens N, Scheveneels W, Schevenels B, Cader MZ, Talbot K, Kozikowski AP, Vanden Berghe P, Van Damme P, Robberecht W, Van Den Bosch L. HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease. Brain : a Journal of Neurology. PMID 29415205 DOI: 10.1093/Brain/Awx375 |
0.386 |
|
| 2018 |
Keogh MJ, Wei W, Aryaman J, Wilson I, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Jones N, et al. Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29332010 DOI: 10.1136/Jnnp-2017-317234 |
0.348 |
|
| 2018 |
Thompson AG, Gray E, Thézénas ML, Charles PD, Evetts S, Hu MT, Talbot K, Fischer R, Kessler BM, Turner MR. Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis. Annals of Neurology. PMID 29331073 DOI: 10.1002/Ana.25143 |
0.38 |
|
| 2018 |
Menke RAL, Proudfoot M, Talbot K, Turner MR. The two-year progression of structural and functional cerebral MRI in amyotrophic lateral sclerosis. Neuroimage. Clinical. 17: 953-961. PMID 29321969 DOI: 10.1016/J.Nicl.2017.12.025 |
0.313 |
|
| 2017 |
Wood MJA, Talbot K, Bowerman M. Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. Human Molecular Genetics. 26: R151-R159. PMID 28977438 DOI: 10.1093/Hmg/Ddx215 |
0.487 |
|
| 2017 |
Al-Chalabi A, Andersen PM, Chandran S, Chio A, Corcia P, Couratier P, Danielsson O, de Carvalho M, Desnuelle C, Grehl T, Grosskreutz J, Holmøy T, Ingre C, Karlsborg M, Kleveland G, ... ... Talbot K, et al. July 2017 ENCALS statement on edaravone. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-4. PMID 28975816 DOI: 10.1080/21678421.2017.1369125 |
0.401 |
|
| 2017 |
Bowerman M, Becker CG, Yáñez-Muñoz RJ, Ning K, Wood MJA, Gillingwater TH, Talbot K. Therapeutic strategies for spinal muscular atrophy: SMN and beyond. Disease Models & Mechanisms. 10: 943-954. PMID 28768735 DOI: 10.1242/Dmm.030148 |
0.493 |
|
| 2017 |
Talbot K, Tizzano EF. The clinical landscape for SMA in a new therapeutic era. Gene Therapy. PMID 28644430 DOI: 10.1038/Gt.2017.52 |
0.453 |
|
| 2017 |
Turner MR, Al-Chalabi A, Chio A, Hardiman O, Kiernan MC, Rohrer JD, Rowe J, Seeley W, Talbot K. Genetic screening in sporadic ALS and FTD. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28642287 DOI: 10.1136/Jnnp-2017-315995 |
0.371 |
|
| 2017 |
Christie-Brown V, Mitchell J, Talbot K. The SMA Trust: the role of a disease-focused research charity in developing treatments for SMA. Gene Therapy. PMID 28561814 DOI: 10.1038/Gt.2017.47 |
0.41 |
|
| 2017 |
Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, ... ... Talbot K, et al. Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28469040 DOI: 10.1126/Scitranslmed.Aad9157 |
0.474 |
|
| 2017 |
Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Zhang Q, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL, Schiavo G. Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28351971 DOI: 10.1073/Pnas.1614557114 |
0.809 |
|
| 2017 |
Aoki Y, Manzano R, Lee Y, Dafinca R, Aoki M, Douglas AG, Varela MA, Sathyaprakash C, Scaber J, Barbagallo P, Vader P, Mäger I, Ezzat K, Turner MR, Ito N, ... ... Talbot K, et al. C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia. Brain : a Journal of Neurology. PMID 28334866 DOI: 10.1016/S0960-8966(17)30312-7 |
0.425 |
|
| 2017 |
Douglas AG, Andreoletti G, Talbot K, Hammans SR, Singh J, Whitney A, Ennis S, Foulds NC. ADCY5-related dyskinesia presenting as familial myoclonus-dystonia. Neurogenetics. PMID 28229249 DOI: 10.1007/S10048-017-0510-Z |
0.342 |
|
| 2017 |
Wei W, Keogh MJ, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akinibi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, et al. Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains. Acta Neuropathologica Communications. 5: 13. PMID 28153046 DOI: 10.1186/S40478-016-0404-6 |
0.361 |
|
| 2017 |
Sandor C, Honti F, Haerty W, Szewczyk-Krolikowski K, Tomlinson P, Evetts S, Millin S, Keane T, McCarthy SA, Durbin R, Talbot K, Hu M, Webber C, Ponting CP, Wade-Martins R. Whole-exome sequencing of 228 patients with sporadic Parkinson's disease. Scientific Reports. 7: 41188. PMID 28117402 DOI: 10.1038/Srep41188 |
0.339 |
|
| 2017 |
Thompson AG, Blackwell V, Marsden R, Millard E, Lawson C, Nickol AH, East JE, Talbot K, Allan PJ, Turner MR. A risk stratifying tool to facilitate safe late-stage percutaneous endoscopic gastrostomy in ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-6. PMID 28100064 DOI: 10.1080/21678421.2016.1274330 |
0.327 |
|
| 2017 |
Turner MR, Talbot K. Sweet food preference in amyotrophic lateral sclerosis. Practical Neurology. PMID 28073920 DOI: 10.1136/Practneurol-2016-001554 |
0.329 |
|
| 2017 |
Talbot K. 1825 Anti-sense treatment in sma: a landmark in the therapy of motor neuron diseases Journal of Neurology, Neurosurgery, and Psychiatry. 88. DOI: 10.1136/Jnnp-2017-Abn.37 |
0.487 |
|
| 2017 |
Lim CR, Goh KJ, Phan YX, Patel J, Shahrizaila N, Loh EC, Ng WF, Capelle DP, Hunter E, Salter M, Elvidge W, Ramadass A, Green J, Kent L, Ossher L, ... ... Talbot K, et al. Epigenetic signatures and early detection of neurodegenerative diseases: Development of stratifying biomarkers for amyotrophic lateral sclerosis in Asian cohorts Journal of the Neurological Sciences. 381: 616-616. DOI: 10.1016/J.Jns.2017.08.1736 |
0.319 |
|
| 2016 |
Keogh MJ, Wei W, Wilson I, Coxhead J, Ryan S, Rollinson S, Griffin H, Kurzawa-Akanbi M, Santibanez-Koref M, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, et al. Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource. Genome Research. PMID 28003435 DOI: 10.1101/Gr.210609.116 |
0.3 |
|
| 2016 |
Scaber J, Talbot K. What is the role of TDP-43 in C9orf72-related amyotrophic lateral sclerosis and frontemporal dementia? Brain : a Journal of Neurology. 139: 3057-3059. PMID 27913405 DOI: 10.1093/Brain/Aww264 |
0.411 |
|
| 2016 |
Abdel-Khalik J, Yutuc E, Crick PJ, Gustafsson JÅ, Warner M, Roman G, Talbot K, Gray E, Griffiths WJ, Turner MR, Wang Y. Defective cholesterol metabolism in amyotrophic lateral sclerosis. Journal of Lipid Research. PMID 27811233 DOI: 10.1194/Jlr.P071639 |
0.315 |
|
| 2016 |
Turner MR, Goldacre R, Talbot K, Goldacre MJ. Psychiatric disorders prior to amyotrophic lateral sclerosis. Annals of Neurology. PMID 27761925 DOI: 10.1002/Ana.24801 |
0.331 |
|
| 2016 |
Proudfoot M, Rohenkohl G, Quinn A, Colclough GL, Wuu J, Talbot K, Woolrich MW, Benatar M, Nobre AC, Turner MR. Altered cortical beta-band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis. Human Brain Mapping. PMID 27623516 DOI: 10.1002/Hbm.23357 |
0.414 |
|
| 2016 |
Hammond SM, Hazell G, Shabanpoor F, Saleh AF, Bowerman M, Sleigh JN, Meijboom KE, Zhou H, Muntoni F, Talbot K, Gait MJ, Wood MJ. Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621445 DOI: 10.1073/Pnas.1605731113 |
0.794 |
|
| 2016 |
Nolan M, Talbot K, Ansorge O. Pathogenesis of FUS-associated ALS and FTD: insights from rodent models. Acta Neuropathologica Communications. 4: 99. PMID 27600654 DOI: 10.1186/S40478-016-0358-8 |
0.422 |
|
| 2016 |
Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, ... ... Talbot K, et al. NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nature Genetics. PMID 27455347 DOI: 10.1038/Ng.3626 |
0.415 |
|
| 2016 |
Marsden R, Allan P, Blackwell V, East J, Lawson C, Nickol AH, Millard E, Talbot K, Thompson AG, Turner MR. Nutritional pathway for people with motor neurone disease. British Journal of Community Nursing. 21: 360-3. PMID 27401201 DOI: 10.12968/Bjcn.2016.21.7.360 |
0.39 |
|
| 2016 |
Talbot K. Clinical tool for predicting survival in ALS: do we need one? Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27378084 DOI: 10.1136/Jnnp-2016-313683 |
0.346 |
|
| 2016 |
McDermott CJ, Bradburn MJ, Maguire C, Cooper CL, Baird WO, Baxter SK, Cohen J, Cantrill H, Dixon S, Ackroyd R, Baudouin S, Bentley A, Berrisford R, Bianchi S, Bourke SC, ... ... Talbot K, et al. DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial. Health Technology Assessment (Winchester, England). 20: 1-186. PMID 27353839 DOI: 10.3310/Hta20450 |
0.332 |
|
| 2016 |
Thompson AG, Gray E, Heman-Ackah SM, Mäger I, Talbot K, Andaloussi SE, Wood MJ, Turner MR. Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers. Nature Reviews. Neurology. PMID 27174238 DOI: 10.1038/Nrneurol.2016.68 |
0.329 |
|
| 2016 |
Dafinca R, Scaber J, Ababneh N, Lalic T, Weir G, Christian H, Vowles J, Douglas AG, Fletcher-Jones A, Browne C, Nakanishi M, Turner MR, Wade-Martins R, Cowley SA, Talbot K. C9orf72 Hexanucleotide Expansions are Associated with Altered ER Calcium Homeostasis and Stress Granule Formation in iPSC-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Stem Cells (Dayton, Ohio). PMID 27097283 DOI: 10.1002/Stem.2388 |
0.515 |
|
| 2016 |
Fernandes HJ, Hartfield EM, Christian HC, Emmanoulidou E, Zheng Y, Booth H, Bogetofte H, Lang C, Ryan BJ, Sardi SP, Badger J, Vowles J, Evetts S, Tofaris GK, Vekrellis K, ... Talbot K, et al. ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons. Stem Cell Reports. PMID 26905200 DOI: 10.1016/J.Stemcr.2016.01.013 |
0.385 |
|
| 2016 |
Menke RA, Proudfoot M, Wuu J, Andersen PM, Talbot K, Benatar M, Turner MR. Increased functional connectivity common to symptomatic amyotrophic lateral sclerosis and those at genetic risk. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26733601 DOI: 10.1136/Jnnp-2015-311945 |
0.372 |
|
| 2016 |
Aoki Y, Manzano R, Takeda S, Talbot K, Wood M. 741. Development of LNA Gapmer Oligonucleotide Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion Molecular Therapy. 24: S292. DOI: 10.1016/S1525-0016(16)33549-3 |
0.452 |
|
| 2016 |
Proudfoot M, Rohenkohl G, Gould I, Wuu J, Andersen PM, Talbot K, Woolrich MW, Benatar M, Nobre AC, Turner MR. Changes in cortical β-oscillation dynamics across the clinical spectrum of motor neuron disease The Lancet. 387: S84. DOI: 10.1016/S0140-6736(16)00471-2 |
0.463 |
|
| 2015 |
Somers E, Lees RD, Hoban K, Sleigh JN, Zhou H, Muntoni F, Talbot K, Gillingwater TH, Parson SH. Vascular defects and spinal cord hypoxia in spinal muscular atrophy. Annals of Neurology. PMID 26506088 DOI: 10.1002/Ana.24549 |
0.813 |
|
| 2015 |
Simon NG, Huynh W, Vucic S, Talbot K, Kiernan MC. Motor neuron disease: current management and future prospects. Internal Medicine Journal. 45: 1005-13. PMID 26429216 DOI: 10.1111/Imj.12874 |
0.484 |
|
| 2015 |
Menke RA, Gray E, Lu CH, Kuhle J, Talbot K, Malaspina A, Turner MR. CSF neurofilament light chain reflects corticospinal tract degeneration in ALS. Annals of Clinical and Translational Neurology. 2: 748-55. PMID 26273687 DOI: 10.1002/Acn3.212 |
0.381 |
|
| 2015 |
Turner MR, Goldacre R, Talbot K, Goldacre MJ. Cerebrovascular injury as a risk factor for amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26260352 DOI: 10.1136/Jnnp-2015-311157 |
0.318 |
|
| 2015 |
McDermott CJ, Bradburn MJ, Maguire C, Cooper CL, Baird WO, Baxter SK, Bourke SC, Imam I, Bentley A, Ealing J, Elliott M, Hanemann CO, Hughes P, ... ... Talbot K, et al. Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial. The Lancet. Neurology. 14: 883-92. PMID 26234554 DOI: 10.1016/S1474-4422(15)00152-0 |
0.314 |
|
| 2015 |
Gray E, Larkin JR, Claridge TD, Talbot K, Sibson NR, Turner MR. The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 26121274 DOI: 10.3109/21678421.2015.1053490 |
0.361 |
|
| 2015 |
Grice SJ, Sleigh JN, Motley WW, Liu JL, Burgess RW, Talbot K, Cader MZ. Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology. Human Molecular Genetics. 24: 4397-406. PMID 25972375 DOI: 10.1093/Hmg/Ddv176 |
0.817 |
|
| 2015 |
Lu CH, Macdonald-Wallis C, Gray E, Pearce N, Petzold A, Norgren N, Giovannoni G, Fratta P, Sidle K, Fish M, Orrell R, Howard R, Talbot K, Greensmith L, Kuhle J, et al. Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis. Neurology. 84: 2247-57. PMID 25934855 DOI: 10.1212/Wnl.0000000000001642 |
0.352 |
|
| 2015 |
Tomlinson PR, Zheng Y, Fischer R, Heidasch R, Gardiner C, Evetts S, Hu M, Wade-Martins R, Turner MR, Morris J, Talbot K, Kessler BM, Tofaris GK. Identification of distinct circulating exosomes in Parkinson's disease. Annals of Clinical and Translational Neurology. 2: 353-61. PMID 25909081 DOI: 10.1002/Acn3.175 |
0.333 |
|
| 2015 |
Mutihac R, Alegre-Abarrategui J, Gordon D, Farrimond L, Yamasaki-Mann M, Talbot K, Wade-Martins R. TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca²⁺ signaling in motor neurons. Neurobiology of Disease. 75: 64-77. PMID 25526708 DOI: 10.1016/J.Nbd.2014.12.010 |
0.42 |
|
| 2015 |
Mutihac R, Ababneh N, Scaber J, Wade-Martins R, Cowley S, Talbot K. Modelling amyotrophic lateral sclerosis (ALS) using mutant and CAS9/CRISPR-corrected motor neurons from patients with C9ORF72 mutations reveals disease-specific cellular phenotypes Journal of the Neurological Sciences. 357. DOI: 10.1016/J.Jns.2015.08.198 |
0.545 |
|
| 2014 |
Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp S, Kenna KP, Scotter EL, Kost J, Keagle P, Miller JW, Calini D, Vance C, Danielson EW, Troakes C, Tiloca C, ... ... Talbot K, et al. Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS. Neuron. 84: 324-31. PMID 25374358 DOI: 10.1016/J.Neuron.2014.09.027 |
0.408 |
|
| 2014 |
Talbot K, Vincent A. Advances in the clinical science of the motor unit: from motor neuron to neuromuscular junction. Current Opinion in Neurology. 27: 503-5. PMID 25159932 DOI: 10.1097/Wco.0000000000000139 |
0.427 |
|
| 2014 |
Menke RA, Körner S, Filippini N, Douaud G, Knight S, Talbot K, Turner MR. Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 137: 2546-55. PMID 24951638 DOI: 10.1093/Brain/Awu162 |
0.404 |
|
| 2014 |
Kent L, Vizard TN, Smith BN, Topp SD, Vance C, Gkazi A, Miller J, Shaw CE, Talbot K. Autosomal dominant inheritance of rapidly progressive amyotrophic lateral sclerosis due to a truncation mutation in the fused in sarcoma (FUS) gene. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 557-62. PMID 24899262 DOI: 10.3109/21678421.2014.920033 |
0.45 |
|
| 2014 |
Bäumer D, East SZ, Tseu B, Zeman A, Hilton D, Talbot K, Ansorge O. FTLD-ALS of TDP-43 type and SCA2 in a family with a full ataxin-2 polyglutamine expansion. Acta Neuropathologica. 128: 597-604. PMID 24718895 DOI: 10.1007/S00401-014-1277-Z |
0.436 |
|
| 2014 |
Bäumer D, Talbot K, Turner MR. Advances in motor neurone disease. Journal of the Royal Society of Medicine. 107: 14-21. PMID 24399773 DOI: 10.1177/0141076813511451 |
0.537 |
|
| 2014 |
Sleigh JN, Grice SJ, Burgess RW, Talbot K, Cader MZ. Neuromuscular junction maturation defects precede impaired lower motor neuron connectivity in Charcot-Marie-Tooth type 2D mice. Human Molecular Genetics. 23: 2639-50. PMID 24368416 DOI: 10.1093/Hmg/Ddt659 |
0.811 |
|
| 2014 |
Feigin A, Talbot K. Expanding the genetics of huntingtonism. Neurology. 82: 286-7. PMID 24363136 DOI: 10.1212/Wnl.0000000000000067 |
0.351 |
|
| 2014 |
Bäumer D, Butterworth R, Menke RA, Talbot K, Hofer M, Turner MR. Progressive hemiparesis (Mills syndrome) with aphasia in amyotrophic lateral sclerosis. Neurology. 82: 457-8. PMID 24363135 DOI: 10.1212/Wnl.0000000000000090 |
0.482 |
|
| 2014 |
Turner BJ, Alfazema N, Sheean RK, Sleigh JN, Davies KE, Horne MK, Talbot K. Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice. Neurobiology of Aging. 35: 906-15. PMID 24210254 DOI: 10.1016/J.Neurobiolaging.2013.09.030 |
0.831 |
|
| 2014 |
Rolinski M, Szewczyk-Krolikowski K, Tomlinson PR, Nithi K, Talbot K, Ben-Shlomo Y, Hu MT. REM sleep behaviour disorder is associated with worse quality of life and other non-motor features in early Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 560-6. PMID 24187013 DOI: 10.1136/Jnnp-2013-306104 |
0.35 |
|
| 2014 |
Szewczyk-Krolikowski K, Tomlinson P, Nithi K, Wade-Martins R, Talbot K, Ben-Shlomo Y, Hu MT. The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort. Parkinsonism & Related Disorders. 20: 99-105. PMID 24183678 DOI: 10.1016/J.Parkreldis.2013.09.025 |
0.368 |
|
| 2014 |
Sleigh JN, Barreiro-Iglesias A, Oliver PL, Biba A, Becker T, Davies KE, Becker CG, Talbot K. Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy. Human Molecular Genetics. 23: 855-69. PMID 24067532 DOI: 10.1093/Hmg/Ddt477 |
0.823 |
|
| 2014 |
Talbot K. Amyotrophic lateral sclerosis: cell vulnerability or system vulnerability? Journal of Anatomy. 224: 45-51. PMID 24010870 DOI: 10.1111/Joa.12107 |
0.442 |
|
| 2014 |
Talbot K. Should all patients with ALS have genetic testing? Journal of Neurology, Neurosurgery, and Psychiatry. 85: 475. PMID 23868948 DOI: 10.1136/Jnnp-2013-305727 |
0.376 |
|
| 2013 |
Németh AH, Kwasniewska AC, Lise S, Parolin Schnekenberg R, Becker EB, Bera KD, Shanks ME, Gregory L, Buck D, Zameel Cader M, Talbot K, de Silva R, Fletcher N, Hastings R, Jayawant S, et al. Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model. Brain : a Journal of Neurology. 136: 3106-18. PMID 24030952 DOI: 10.1093/Brain/Awt236 |
0.661 |
|
| 2013 |
Turner MR, Goldacre R, Ramagopalan S, Talbot K, Goldacre MJ. Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study. Neurology. 81: 1222-5. PMID 23946298 DOI: 10.1212/Wnl.0B013E3182A6Cc13 |
0.371 |
|
| 2013 |
Halpin L, Savulescu J, Talbot K, Turner M, Talman P. Improving access to medicines: empowering patients in the quest to improve treatment for rare lethal diseases. Journal of Medical Ethics. PMID 23839261 DOI: 10.1136/Medethics-2013-101427 |
0.345 |
|
| 2013 |
Kolind S, Sharma R, Knight S, Johansen-Berg H, Talbot K, Turner MR. Myelin imaging in amyotrophic and primary lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 562-73. PMID 23678852 DOI: 10.3109/21678421.2013.794843 |
0.397 |
|
| 2013 |
Hobson EV, McGeachan A, Al-Chalabi A, Chandran S, Crawley F, Dick D, Donaghy C, Ealing J, Ellis CM, Gorrie G, Hanemann CO, Harrower T, Jung A, Majeed T, Malaspina A, ... ... Talbot K, et al. Management of sialorrhoea in motor neuron disease: a survey of current UK practice. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 521-7. PMID 23647474 DOI: 10.3109/21678421.2013.790452 |
0.394 |
|
| 2013 |
Turner MR, Talbot K. Mimics and chameleons in motor neurone disease. Practical Neurology. 13: 153-64. PMID 23616620 DOI: 10.1136/Practneurol-2013-000557 |
0.418 |
|
| 2013 |
Kayadjanian N, Burghes A, Finkel RS, Mercuri E, Rouault F, Schwersenz I, Talbot K. SMA-EUROPE workshop report: Opportunities and challenges in developing clinical trials for spinal muscular atrophy in Europe. Orphanet Journal of Rare Diseases. 8: 44. PMID 23514578 DOI: 10.1186/1750-1172-8-44 |
0.329 |
|
| 2013 |
Morrison KE, Dhariwal S, Hornabrook R, Savage L, Burn DJ, Khoo TK, Kelly J, Murphy CL, Al-Chalabi A, Dougherty A, Leigh PN, Wijesekera L, Thornhill M, Ellis CM, ... ... Talbot K, et al. Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. Neurology. 12: 339-45. PMID 23453347 DOI: 10.1016/S1474-4422(13)70037-1 |
0.351 |
|
| 2013 |
Stamelou M, Adams M, Davagnanam I, Batla A, Sheerin U, Talbot K, Bhatia KP. Progressive ataxia and palatal tremor associated with dense pontine calcification: A unique case. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 1155-7. PMID 23436739 DOI: 10.1002/Mds.25310 |
0.363 |
|
| 2013 |
Turner MR, Hardiman O, Benatar M, Brooks BR, Chio A, de Carvalho M, Ince PG, Lin C, Miller RG, Mitsumoto H, Nicholson G, Ravits J, Shaw PJ, Swash M, Talbot K, et al. Controversies and priorities in amyotrophic lateral sclerosis. The Lancet. Neurology. 12: 310-22. PMID 23415570 DOI: 10.1016/S1474-4422(13)70036-X |
0.629 |
|
| 2013 |
Kent L, Davies P, Kennett R, Wimalaratna S, Kerr R, Turner MR, Talbot K. Unmasking of incipient amyotrophic lateral sclerosis by botulinum toxin therapy. Journal of Neurology. 260: 1166-7. PMID 23400499 DOI: 10.1007/S00415-013-6854-X |
0.407 |
|
| 2013 |
Sleigh JN, Grice SJ, Davies KE, Talbot K. Spinal muscular atrophy at the crossroads of basic science and therapy. Neuromuscular Disorders : Nmd. 23: 96. PMID 22981697 DOI: 10.1016/J.Nmd.2012.08.008 |
0.811 |
|
| 2013 |
Vester A, Velez-Ruiz G, McLaughlin HM, Lupski JR, Talbot K, Vance JM, Züchner S, Roda RH, Fischbeck KH, Biesecker LG, Nicholson G, Beg AA, Antonellis A. A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo. Human Mutation. 34: 191-9. PMID 22930593 DOI: 10.1002/Humu.22210 |
0.414 |
|
| 2012 |
Turner MR, Talbot K. Motor neurone disease is a clinical diagnosis. Practical Neurology. 12: 396-7. PMID 23144309 DOI: 10.1136/Practneurol-2012-000374 |
0.443 |
|
| 2012 |
McDermott CJ, Maguire C, Cooper CL, Ackroyd R, Baird WO, Baudouin S, Bentley A, Bianchi S, Bourke S, Bradburn MJ, Dixon S, Ealing J, Galloway S, Karat D, Maynard N, ... ... Talbot K, et al. Protocol for diaphragm pacing in patients with respiratory muscle weakness due to motor neurone disease (DiPALS): a randomised controlled trial. Bmc Neurology. 12: 74. PMID 22897892 DOI: 10.1186/1471-2377-12-74 |
0.396 |
|
| 2012 |
Hoffman EP, Talbot K. A calm before the exome storm: coming together of dSMA and CMT2. Neurology. 78: 1706-7. PMID 22459684 DOI: 10.1212/Wnl.0B013E3182556C1F |
0.425 |
|
| 2012 |
Majounie E, Renton AE, Mok K, Dopper EG, Waite A, Rollinson S, Chiò A, Restagno G, Nicolaou N, Simon-Sanchez J, van Swieten JC, Abramzon Y, Johnson JO, Sendtner M, Pamphlett R, ... ... Talbot K, et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. The Lancet. Neurology. 11: 323-30. PMID 22406228 DOI: 10.1016/S1474-4422(12)70043-1 |
0.585 |
|
| 2012 |
Evans MC, Modo M, Talbot K, Sibson N, Turner MR. Magnetic resonance imaging of pathological processes in rodent models of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 288-301. PMID 22117132 DOI: 10.3109/17482968.2011.623300 |
0.393 |
|
| 2012 |
Turner MR, Wotton C, Talbot K, Goldacre MJ. Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: indirect evidence from record linkage study. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 395-8. PMID 22072701 DOI: 10.1136/Jnnp-2011-301161 |
0.329 |
|
| 2012 |
McLaughlin HM, Sakaguchi R, Giblin W, Wilson TE, Biesecker L, Lupski JR, Talbot K, Vance JM, Züchner S, Lee YC, Kennerson M, Hou YM, Nicholson G, Antonellis A. A recurrent loss-of-function alanyl-tRNA synthetase (AARS) mutation in patients with Charcot-Marie-Tooth disease type 2N (CMT2N). Human Mutation. 33: 244-53. PMID 22009580 DOI: 10.1002/Humu.21635 |
0.401 |
|
| 2012 |
Turner M, Wotton C, Talbot K, Goldacre MJ. 1118 Are MND patients pre-morbidly fitter? Indirect evidence from hospital record-linkage Journal of Neurology, Neurosurgery & Psychiatry. 83: e1.90-e1. DOI: 10.1136/Jnnp-2011-301993.18 |
0.302 |
|
| 2011 |
Motley WW, Seburn KL, Nawaz MH, Miers KE, Cheng J, Antonellis A, Green ED, Talbot K, Yang XL, Fischbeck KH, Burgess RW. Charcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levels. Plos Genetics. 7: e1002399. PMID 22144914 DOI: 10.1371/Journal.Pgen.1002399 |
0.705 |
|
| 2011 |
Gibbons CJ, Mills RJ, Thornton EW, Ealing J, Mitchell JD, Shaw PJ, Talbot K, Tennant A, Young CA. Development of a patient reported outcome measure for fatigue in motor neurone disease: the Neurological Fatigue Index (NFI-MND). Health and Quality of Life Outcomes. 9: 101. PMID 22107756 DOI: 10.1186/1477-7525-9-101 |
0.324 |
|
| 2011 |
Douaud G, Filippini N, Knight S, Talbot K, Turner MR. Integration of structural and functional magnetic resonance imaging in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 134: 3470-9. PMID 22075069 DOI: 10.1093/Brain/Awr279 |
0.334 |
|
| 2011 |
Talbot K. Familial versus sporadic amyotrophic lateral sclerosis--a false dichotomy? Brain : a Journal of Neurology. 134: 3429-31. PMID 22051609 DOI: 10.1093/Brain/Awr296 |
0.396 |
|
| 2011 |
Kwok AS, Phadwal K, Turner BJ, Oliver PL, Raw A, Simon AK, Talbot K, Agashe VR. HspB8 mutation causing hereditary distal motor neuropathy impairs lysosomal delivery of autophagosomes. Journal of Neurochemistry. 119: 1155-61. PMID 21985219 DOI: 10.1111/J.1471-4159.2011.07521.X |
0.713 |
|
| 2011 |
Mutsaers CA, Wishart TM, Lamont DJ, Riessland M, Schreml J, Comley LH, Murray LM, Parson SH, Lochmüller H, Wirth B, Talbot K, Gillingwater TH. Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Human Molecular Genetics. 20: 4334-44. PMID 21840928 DOI: 10.1093/Hmg/Ddr360 |
0.404 |
|
| 2011 |
Sharma R, Hicks S, Berna CM, Kennard C, Talbot K, Turner MR. Oculomotor dysfunction in amyotrophic lateral sclerosis: a comprehensive review. Archives of Neurology. 68: 857-61. PMID 21747027 DOI: 10.1001/Archneurol.2011.130 |
0.422 |
|
| 2011 |
Sleigh JN, Gillingwater TH, Talbot K. The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy. Disease Models & Mechanisms. 4: 457-67. PMID 21708901 DOI: 10.1242/Dmm.007245 |
0.83 |
|
| 2011 |
Turner MR, Wicks P, Brownstein CA, Massagli MP, Toronjo M, Talbot K, Al-Chalabi A. Concordance between site of onset and limb dominance in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 853-4. PMID 20562391 DOI: 10.1136/Jnnp.2010.208413 |
0.407 |
|
| 2011 |
Talbot K. S.I.2 Motor neuron disorders and vulnerability to RNA processing Neuromuscular Disorders. 21: 680. DOI: 10.1016/J.Nmd.2011.06.888 |
0.383 |
|
| 2010 |
Talbot K. Do twin studies still have anything to teach us about the genetics of amyotrophic lateral sclerosis? Journal of Neurology, Neurosurgery, and Psychiatry. 81: 1299-300. PMID 21087924 DOI: 10.1136/Jnnp.2010.224816 |
0.411 |
|
| 2010 |
Filippini N, Douaud G, Mackay CE, Knight S, Talbot K, Turner MR. Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis. Neurology. 75: 1645-52. PMID 21041787 DOI: 10.1212/Wnl.0B013E3181Fb84D1 |
0.468 |
|
| 2010 |
McLaughlin HM, Sakaguchi R, Liu C, Igarashi T, Pehlivan D, Chu K, Iyer R, Cruz P, Cherukuri PF, Hansen NF, Mullikin JC, Biesecker LG, Wilson TE, Ionasescu V, ... ... Talbot K, et al. Compound heterozygosity for loss-of-function lysyl-tRNA synthetase mutations in a patient with peripheral neuropathy. American Journal of Human Genetics. 87: 560-6. PMID 20920668 DOI: 10.1016/J.Ajhg.2010.09.008 |
0.425 |
|
| 2010 |
Wishart TM, Huang JP, Murray LM, Lamont DJ, Mutsaers CA, Ross J, Geldsetzer P, Ansorge O, Talbot K, Parson SH, Gillingwater TH. SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy. Human Molecular Genetics. 19: 4216-28. PMID 20705736 DOI: 10.1093/Hmg/Ddq340 |
0.456 |
|
| 2010 |
Bäumer D, Hilton D, Paine SM, Turner MR, Lowe J, Talbot K, Ansorge O. Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations. Neurology. 75: 611-8. PMID 20668261 DOI: 10.1212/Wnl.0B013E3181Ed9Cde |
0.481 |
|
| 2010 |
Bäumer D, Ansorge O, Almeida M, Talbot K. The role of RNA processing in the pathogenesis of motor neuron degeneration. Expert Reviews in Molecular Medicine. 12: e21. PMID 20642879 DOI: 10.1017/S1462399410001523 |
0.526 |
|
| 2010 |
Turner MR, Scaber J, Goodfellow JA, Lord ME, Marsden R, Talbot K. The diagnostic pathway and prognosis in bulbar-onset amyotrophic lateral sclerosis. Journal of the Neurological Sciences. 294: 81-5. PMID 20452624 DOI: 10.1016/J.Jns.2010.03.028 |
0.363 |
|
| 2010 |
Southgate L, Dafou D, Hoyle J, Li N, Kinning E, Critchley P, Németh AH, Talbot K, Bindu PS, Sinha S, Taly AB, Raghavendra S, Müller F, Maher ER, Trembath RC. Novel SPG11 mutations in Asian kindreds and disruption of spatacsin function in the zebrafish. Neurogenetics. 11: 379-89. PMID 20390432 DOI: 10.1007/S10048-010-0243-8 |
0.389 |
|
| 2010 |
Murray LM, Talbot K, Gillingwater TH. Review: neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy. Neuropathology and Applied Neurobiology. 36: 133-56. PMID 20202121 DOI: 10.1111/J.1365-2990.2010.01061.X |
0.469 |
|
| 2010 |
Motley WW, Talbot K, Fischbeck KH. GARS axonopathy: not every neuron's cup of tRNA. Trends in Neurosciences. 33: 59-66. PMID 20152552 DOI: 10.1016/J.Tins.2009.11.001 |
0.7 |
|
| 2010 |
Turner BJ, Ackerley S, Davies KE, Talbot K. Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice. Human Molecular Genetics. 19: 815-24. PMID 20008901 DOI: 10.1093/Hmg/Ddp550 |
0.724 |
|
| 2010 |
Turner MR, Brockington A, Scaber J, Hollinger H, Marsden R, Shaw PJ, Talbot K. Pattern of spread and prognosis in lower limb-onset ALS. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 369-73. PMID 20001488 DOI: 10.3109/17482960903420140 |
0.349 |
|
| 2010 |
Murray LM, Lee S, Bäumer D, Parson SH, Talbot K, Gillingwater TH. Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy. Human Molecular Genetics. 19: 420-33. PMID 19884170 DOI: 10.1093/Hmg/Ddp506 |
0.525 |
|
| 2010 |
Turner MR, Abisgold J, Yeates DG, Talbot K, Goldacre MJ. Head and other physical trauma requiring hospitalisation is not a significant risk factor in the development of ALS. Journal of the Neurological Sciences. 288: 45-8. PMID 19878957 DOI: 10.1016/J.Jns.2009.10.010 |
0.316 |
|
| 2010 |
Pereira EA, Turner MR, Wass JA, Talbot K. Reduction of elevated IGF-1 levels in coincident amyotrophic lateral sclerosis and acromegaly. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 255-7. PMID 19634028 DOI: 10.3109/17482960902870985 |
0.405 |
|
| 2010 |
Talbot K, Lowe J, Ansorge O, Hilton D, Baumer D, Paine S, Turner M. PATU5 Characterisation of fused in sarcoma pathology and FUS mutations in juvenile amyotrophic lateral sclerosis with basophilic inclusions Journal of Neurology, Neurosurgery & Psychiatry. 81: e25-e25. DOI: 10.1136/Jnnp.2010.226340.34 |
0.474 |
|
| 2010 |
Talbot K, Turner MR. PORT02 Oxford motor neurone disorders research Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.226340.197 |
0.457 |
|
| 2010 |
Hu M, Ponting C, Mackay C, Talbot K, Wade-Martins R, Wood M, Bolam JP, Ben-Shlomo Y, Ansorge O, James W. POMD09 Understanding the early pathological pathways in Parkinson's disease. The Oxford Parkinson's Disease Centre Journal of Neurology, Neurosurgery & Psychiatry. 81: e59-e59. DOI: 10.1136/Jnnp.2010.226340.169 |
0.317 |
|
| 2010 |
Filippini N, Douaud G, Mackay CE, Knight S, Talbot K, Turner MR. PATH44 Corpus callosum diffusion tensor imaging as a biomarker for motor neurone disease Journal of Neurology, Neurosurgery & Psychiatry. 81: e19-e20. DOI: 10.1136/Jnnp.2010.226340.12 |
0.413 |
|
| 2010 |
Filippini N, Mackay C, Douaud G, Knight S, Talbot K, Turner M. P89 An MRI biomarker for motor neuron disease? Neuromuscular Disorders. 20: S29. DOI: 10.1016/S0960-8966(10)70104-8 |
0.436 |
|
| 2009 |
Bäumer D, Lee S, Nicholson G, Davies JL, Parkinson NJ, Murray LM, Gillingwater TH, Ansorge O, Davies KE, Talbot K. Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy. Plos Genetics. 5: e1000773. PMID 20019802 DOI: 10.1371/Journal.Pgen.1000773 |
0.753 |
|
| 2009 |
Bäumer D, Parkinson N, Talbot K. TARDBP in amyotrophic lateral sclerosis: identification of a novel variant but absence of copy number variation. Journal of Neurology, Neurosurgery, and Psychiatry. 80: 1283-5. PMID 19864663 DOI: 10.1136/Jnnp.2008.166512 |
0.494 |
|
| 2009 |
Talbot K. Motor neuron disease: the bare essentials. Practical Neurology. 9: 303-9. PMID 19762894 DOI: 10.1136/Jnnp.2009.188151 |
0.515 |
|
| 2009 |
Talbot K. Another gene for ALS: mutations in sporadic cases and the rare variant hypothesis. Neurology. 73: 1172-3. PMID 19741213 DOI: 10.1212/Wnl.0B013E3181Bd1161 |
0.48 |
|
| 2009 |
Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, et al. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms. 2: 359-73. PMID 19470612 DOI: 10.1242/Dmm.002527 |
0.461 |
|
| 2009 |
Turner BJ, Parkinson NJ, Davies KE, Talbot K. Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model. Neurobiology of Disease. 34: 511-7. PMID 19332122 DOI: 10.1016/J.Nbd.2009.03.005 |
0.771 |
|
| 2009 |
Chiò A, Schymick JC, Restagno G, Scholz SW, Lombardo F, Lai SL, Mora G, Fung HC, Britton A, Arepalli S, Gibbs JR, Nalls M, Berger S, Kwee LC, Oddone EZ, ... ... Talbot K, et al. A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 18: 1524-32. PMID 19193627 DOI: 10.1093/Hmg/Ddp059 |
0.792 |
|
| 2009 |
Turner MR, Kiernan MC, Leigh PN, Talbot K. Biomarkers in amyotrophic lateral sclerosis. The Lancet. Neurology. 8: 94-109. PMID 19081518 DOI: 10.1016/S1474-4422(08)70293-X |
0.425 |
|
| 2009 |
Ciccarelli O, Behrens TE, Johansen-Berg H, Talbot K, Orrell RW, Howard RS, Nunes RG, Miller DH, Matthews PM, Thompson AJ, Smith SM. Investigation of white matter pathology in ALS and PLS using tract-based spatial statistics. Human Brain Mapping. 30: 615-24. PMID 18172851 DOI: 10.1002/Hbm.20527 |
0.412 |
|
| 2008 |
Baumer D, Flossmann E, Cudlip S, Quaghebeur G, Jeans A, Talbot K. Primary angiitis of the CNS mimicking a spinal cord tumour. Journal of Neurology. 255: 1970-2. PMID 19165530 DOI: 10.1007/S00415-009-0853-Y |
0.302 |
|
| 2008 |
Turner BJ, Bäumer D, Parkinson NJ, Scaber J, Ansorge O, Talbot K. TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy. Bmc Neuroscience. 9: 104. PMID 18957104 DOI: 10.1186/1471-2202-9-104 |
0.536 |
|
| 2008 |
Doran G, Davies KE, Talbot K. Activation of mutant protein kinase Cgamma leads to aberrant sequestration and impairment of its cellular function. Biochemical and Biophysical Research Communications. 372: 447-53. PMID 18503760 DOI: 10.1016/J.Bbrc.2008.05.072 |
0.667 |
|
| 2008 |
Talbot K, Davies KE. Is good housekeeping the key to motor neuron survival? Cell. 133: 572-4. PMID 18485864 DOI: 10.1016/J.Cell.2008.05.002 |
0.749 |
|
| 2008 |
Parkinson NJ, Baumer D, Rose-Morris A, Talbot K. Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders. Neuromuscular Disorders : Nmd. 18: 394-7. PMID 18395445 DOI: 10.1016/J.Nmd.2008.03.003 |
0.534 |
|
| 2008 |
James PA, Rankin J, Talbot K. Asymmetrical late onset motor neuropathy associated with a novel mutation in the small heat shock protein HSPB1 (HSP27). Journal of Neurology, Neurosurgery, and Psychiatry. 79: 461-3. PMID 18344398 DOI: 10.1136/Jnnp.2007.125179 |
0.464 |
|
| 2008 |
Turner BJ, Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Progress in Neurobiology. 85: 94-134. PMID 18282652 DOI: 10.1016/J.Pneurobio.2008.01.001 |
0.506 |
|
| 2008 |
Murray LM, Comley LH, Thomson D, Parkinson N, Talbot K, Gillingwater TH. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy. Human Molecular Genetics. 17: 949-62. PMID 18065780 DOI: 10.1093/Hmg/Ddm367 |
0.427 |
|
| 2007 |
Talbot K, Davies KE. Chapter 7 Spinal muscular atrophies and hereditary motor neuropathies. Handbook of Clinical Neurology. 82: 141-53. PMID 18808892 DOI: 10.1016/S0072-9752(07)80010-8 |
0.745 |
|
| 2007 |
Turner MR, Chohan G, Quaghebeur G, Greenhall RC, Hadjivassiliou M, Talbot K. A case of celiac disease mimicking amyotrophic lateral sclerosis. Nature Clinical Practice. Neurology. 3: 581-4. PMID 17914346 DOI: 10.1038/Ncpneuro0631 |
0.315 |
|
| 2007 |
Schymick JC, Talbot K, Traynor BJ. Genetics of sporadic amyotrophic lateral sclerosis. Human Molecular Genetics. 16: R233-42. PMID 17911166 DOI: 10.1093/Hmg/Ddm215 |
0.813 |
|
| 2007 |
Talbot K. The study of rare diseases: butterfly collecting or an entrée to understanding common conditions? Practical Neurology. 7: 210-1. PMID 17636135 DOI: 10.1136/Jnnp.2007.124396 |
0.305 |
|
| 2007 |
Cader MZ, Ren J, James PA, Bird LE, Talbot K, Stammers DK. Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. Febs Letters. 581: 2959-64. PMID 17544401 DOI: 10.1016/J.Febslet.2007.05.046 |
0.364 |
|
| 2006 |
James PA, Cader MZ, Muntoni F, Childs AM, Crow YJ, Talbot K. Severe childhood SMA and axonal CMT due to anticodon binding domain mutations in the GARS gene. Neurology. 67: 1710-2. PMID 17101916 DOI: 10.1212/01.Wnl.0000242619.52335.Bc |
0.428 |
|
| 2006 |
Talbot K, Ansorge O. Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease. Human Molecular Genetics. 15: R182-7. PMID 16987882 DOI: 10.1093/Hmg/Ddl202 |
0.441 |
|
| 2006 |
James PA, Talbot K. The molecular genetics of non-ALS motor neuron diseases. Biochimica Et Biophysica Acta. 1762: 986-1000. PMID 16765570 DOI: 10.1016/J.Bbadis.2006.04.003 |
0.533 |
|
| 2006 |
Ackerley S, James PA, Kalli A, French S, Davies KE, Talbot K. A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes. Human Molecular Genetics. 15: 347-54. PMID 16368711 DOI: 10.1093/Hmg/Ddi452 |
0.732 |
|
| 2004 |
Evgrafov OV, Mersiyanova I, Irobi J, Van Den Bosch L, Dierick I, Leung CL, Schagina O, Verpoorten N, Van Impe K, Fedotov V, Dadali E, Auer-Grumbach M, Windpassinger C, Wagner K, Mitrovic Z, ... ... Talbot K, et al. Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. Nature Genetics. 36: 602-6. PMID 15122254 DOI: 10.1038/Ng1354 |
0.434 |
|
| 2004 |
Irobi J, Van Impe K, Seeman P, Jordanova A, Dierick I, Verpoorten N, Michalik A, De Vriendt E, Jacobs A, Van Gerwen V, Vennekens K, Mazanec R, Tournev I, Hilton-Jones D, Talbot K, et al. Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nature Genetics. 36: 597-601. PMID 15122253 DOI: 10.1038/Ng1328 |
0.401 |
|
| 2004 |
Talbot K. Motor neuron disease Medicine. 32: 105-107. DOI: 10.1383/Medc.32.11.105.53361 |
0.484 |
|
| 2004 |
Talbot K. Monomelic amyotrophy or Hirayama's disease Practical Neurology. 4: 362-365. DOI: 10.1111/J.1474-7766.2004.00265.X |
0.417 |
|
| 2003 |
Anderson K, Talbot K. Spinal muscular atrophies reveal motor neuron vulnerability to defects in ribonucleoprotein handling. Current Opinion in Neurology. 16: 595-9. PMID 14501843 DOI: 10.1097/01.Wco.0000093102.34793.13 |
0.51 |
|
| 2003 |
Talbot K, Davies K. Musculoskeletal diseases: from complex genetics to therapy. Current Opinion in Pharmacology. 3: 277-9. PMID 12810192 DOI: 10.1016/S1471-4892(03)00044-4 |
0.629 |
|
| 2002 |
Talbot K. Motor neurone disease. Postgraduate Medical Journal. 78: 513-9. PMID 12357010 DOI: 10.1136/Pmj.78.923.513 |
0.492 |
|
| 2001 |
Talbot K, Davies KE. Spinal muscular atrophy. Seminars in Neurology. 21: 189-97. PMID 11442327 DOI: 10.1055/S-2001-15264 |
0.751 |
|
| 2001 |
Skordis LA, Dunckley MG, Burglen L, Campbell L, Talbot K, Patel S, Melki J, Davies KE, Dubowitz V, Muntoni F. Characterisation of novel point mutations in the survival motor neuron gene SMN, in three patients with SMA. Human Genetics. 108: 356-7. PMID 11379882 DOI: 10.1007/S004390100497 |
0.723 |
|
| 1999 |
Talbot K. Spinal muscular atrophy. Journal of Inherited Metabolic Disease. 22: 545-54. PMID 10407786 DOI: 10.1023/A:1005516625866 |
0.42 |
|
| 1998 |
Talbot K, Miguel-Aliaga I, Mohaghegh P, Ponting CP, Davies KE. Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. Human Molecular Genetics. 7: 2149-56. PMID 9817934 DOI: 10.1093/Hmg/7.13.2149 |
0.708 |
|
| 1997 |
Talbot K. What's new in the molecular genetics of spinal muscular atrophy? European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society. 1: 149-55. PMID 10728211 DOI: 10.1016/S1090-3798(97)80051-7 |
0.311 |
|
| 1997 |
Nesbit MA, Hodges MD, Campbell L, de Meulemeester TM, Alders M, Rodrigues NR, Talbot K, Theodosiou AM, Mannens MA, Nakamura Y, Little PF, Davies KE. Genomic organization and chromosomal localization of a member of the MAP kinase phosphatase gene family to human chromosome 11p15.5 and a pseudogene to 10q11.2. Genomics. 42: 284-94. PMID 9192849 DOI: 10.1006/Geno.1997.4737 |
0.627 |
|
| 1997 |
Talbot K, Rodrigues NR, Ignatius J, Muntoni F, Davies KE. Gene conversion at the SMN locus in autosomal recessive spinal muscular atrophy does not predict a mild phenotype. Neuromuscular Disorders : Nmd. 7: 198-201. PMID 9185185 DOI: 10.1016/S0960-8966(97)00450-1 |
0.738 |
|
| 1997 |
Talbot K, Ponting CP, Theodosiou AM, Rodrigues NR, Surtees R, Mountford R, Davies KE. Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism? Human Molecular Genetics. 6: 497-500. PMID 9147655 DOI: 10.1093/Hmg/6.3.497 |
0.736 |
|
| 1996 |
Talbot K, Rodrigues N, Bernert G, Bittner R, Davies K. Evidence for compound heterozygosity causing mild and severe forms of autosomal recessive spinal muscular atrophy. Journal of Medical Genetics. 33: 1019-21. PMID 9004135 DOI: 10.1136/Jmg.33.12.1019 |
0.737 |
|
| 1996 |
Rodrigues NR, Owen N, Talbot K, Patel S, Muntoni F, Ignatius J, Dubowitz V, Davies KE. Gene deletions in spinal muscular atrophy. Journal of Medical Genetics. 33: 93-6. PMID 8929942 DOI: 10.1136/Jmg.33.2.93 |
0.683 |
|
| 1996 |
Rodrigues NR, Talbot K, Davies KE. Molecular genetics of autosomal recessive spinal muscular atrophy. Molecular Medicine (Cambridge, Mass.). 2: 400-4. PMID 8827710 DOI: 10.1007/Bf03401899 |
0.662 |
|
| 1995 |
Rodrigues NR, Owen N, Talbot K, Ignatius J, Dubowitz V, Davies KE. Deletions in the survival motor neuron gene on 5q13 in autosomal recessive spinal muscular atrophy. Human Molecular Genetics. 4: 631-4. PMID 7633412 DOI: 10.1093/Hmg/4.4.631 |
0.749 |
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