| Year |
Citation |
Score |
| 2020 |
Georgescu MM, Olar A. Genetic and histologic spatiotemporal evolution of recurrent, multifocal, multicentric and metastatic glioblastoma. Acta Neuropathologica Communications. 8: 10. PMID 32014051 DOI: 10.1186/S40478-020-0889-X |
0.356 |
|
| 2016 |
Georgescu MM, Mobley BC, Orr BA, Shang P, Lehman NL, Zhu X, O'Neill TJ, Rajaram V, Hatanpaa KJ, Timmons CF, Raisanen JM. NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors. Acta Neuropathologica Communications. 4: 55. PMID 27229317 DOI: 10.1186/S40478-016-0329-0 |
0.475 |
|
| 2015 |
Georgescu MM, Pinho Mda C, Richardson TE, Torrealba J, Buja LM, Milewicz DM, Raisanen JM, Burns DK. The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease. Acta Neuropathologica Communications. 3: 81. PMID 26637293 DOI: 10.1186/S40478-015-0262-7 |
0.584 |
|
| 2015 |
Georgescu MM, Yell P, Mobley BC, Shang P, Georgescu T, Wang SH, Canoll P, Hatanpaa KJ, White CL, Raisanen JM. NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma. Acta Neuropathologica Communications. 3: 11. PMID 25775275 DOI: 10.1186/S40478-015-0197-Z |
0.564 |
|
| 2014 |
Georgescu MM, Cote G, Agarwal NK, White CL. NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane. Neoplasia (New York, N.Y.). 16: 365-74.e1-2. PMID 24862762 DOI: 10.1016/J.Neo.2014.04.004 |
0.402 |
|
| 2014 |
Agarwal NK, Zhu X, Gagea M, White CL, Cote G, Georgescu MM. PHLPP2 suppresses the NF-κB pathway by inactivating IKKβ kinase. Oncotarget. 5: 815-23. PMID 24553260 DOI: 10.18632/Oncotarget.1774 |
0.319 |
|
| 2013 |
Navalkele DD, Georgescu MM, Burns DK, Greenberg T, Vernino S. Progressive leg pain and weakness. Jama Neurology. 70: 510-4. PMID 23440264 DOI: 10.1001/Jamaneurol.2013.2158 |
0.458 |
|
| 2012 |
Molina JR, Agarwal NK, Morales FC, Hayashi Y, Aldape KD, Cote G, Georgescu MM. PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma. Oncogene. 31: 1264-74. PMID 21804599 DOI: 10.1038/Onc.2011.324 |
0.427 |
|
| 2010 |
Georgescu MM. PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control. Genes & Cancer. 1: 1170-7. PMID 21779440 DOI: 10.1177/1947601911407325 |
0.323 |
|
| 2010 |
Hayashi Y, Molina JR, Hamilton SR, Georgescu MM. NHERF1/EBP50 is a new marker in colorectal cancer. Neoplasia (New York, N.Y.). 12: 1013-22. PMID 21170265 DOI: 10.1593/Neo.10780 |
0.375 |
|
| 2010 |
Molina JR, Morales FC, Hayashi Y, Aldape KD, Georgescu MM. Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation. Cancer Research. 70: 6697-703. PMID 20736378 DOI: 10.1158/0008-5472.Can-10-1271 |
0.431 |
|
| 2010 |
Molina JR, Hayashi Y, Stephens C, Georgescu MM. Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia (New York, N.Y.). 12: 453-63. PMID 20563248 DOI: 10.1593/Neo.10126 |
0.416 |
|
| 2010 |
Morales FC, Molina JR, Hayashi Y, Georgescu MM. Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma. Neuro-Oncology. 12: 528-39. PMID 20156804 DOI: 10.1093/Neuonc/Nop060 |
0.365 |
|
| 2009 |
Mounir Z, Krishnamoorthy JL, Robertson GP, Scheuner D, Kaufman RJ, Georgescu MM, Koromilas AE. Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway. Science Signaling. 2: ra85. PMID 20029030 DOI: 10.1126/Scisignal.2000389 |
0.4 |
|
| 2009 |
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, Habib AA. RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Research. 69: 4107-11. PMID 19435890 DOI: 10.1158/0008-5472.Can-09-0474 |
0.33 |
|
| 2008 |
Georgescu MM, Morales FC, Molina JR, Hayashi Y. Roles of NHERF1/EBP50 in cancer. Current Molecular Medicine. 8: 459-68. PMID 18781953 DOI: 10.2174/156652408785748031 |
0.354 |
|
| 2008 |
Georgescu MM. NHERF1: molecular brake on the PI3K pathway in breast cancer. Breast Cancer Research : Bcr. 10: 106. PMID 18430260 DOI: 10.1186/Bcr1992 |
0.35 |
|
| 2007 |
Kreimann EL, Morales FC, de Orbeta-Cruz J, Takahashi Y, Adams H, Liu TJ, McCrea PD, Georgescu MM. Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function. Oncogene. 26: 5290-9. PMID 17325659 DOI: 10.1038/Sj.Onc.1210336 |
0.336 |
|
| 2007 |
Morales FC, Takahashi Y, Momin S, Adams H, Chen X, Georgescu MM. NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands. Molecular and Cellular Biology. 27: 2527-37. PMID 17242191 DOI: 10.1128/Mcb.01372-06 |
0.334 |
|
| 2006 |
Takahashi Y, Morales FC, Kreimann EL, Georgescu MM. PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling. The Embo Journal. 25: 910-20. PMID 16456542 DOI: 10.1038/Sj.Emboj.7600979 |
0.425 |
|
| 2005 |
Levitt RJ, Georgescu MM, Pollak M. PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2. Biochemical and Biophysical Research Communications. 336: 1056-61. PMID 16154532 DOI: 10.1016/J.Bbrc.2005.08.229 |
0.361 |
|
| 2005 |
Wu Y, Singh S, Georgescu MM, Birge RB. A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells. Journal of Cell Science. 118: 539-53. PMID 15673687 DOI: 10.1242/Jcs.01632 |
0.333 |
|
| 2005 |
Wu Y, Georgescu M, Birge RB. Involvement of PKC Activation in Mer Tyrosine Kinase-Mediated Phagocytosis of Apoptotic Cells. Blood. 106: 3083-3083. DOI: 10.1182/Blood.V106.11.3083.3083 |
0.331 |
|
| 2004 |
Morales FC, Takahashi Y, Kreimann EL, Georgescu MM. Ezrin-radixin-moesin (ERM)-binding phosphoprotein 50 organizes ERM proteins at the apical membrane of polarized epithelia. Proceedings of the National Academy of Sciences of the United States of America. 101: 17705-10. PMID 15591354 DOI: 10.1073/Pnas.0407974101 |
0.367 |
|
| 2004 |
Sumitomo M, Iwase A, Zheng R, Navarro D, Kaminetzky D, Shen R, Georgescu MM, Nanus DM. Synergy in tumor suppression by direct interaction of neutral endopeptidase with PTEN. Cancer Cell. 5: 67-78. PMID 14749127 DOI: 10.1016/S1535-6108(03)00331-3 |
0.432 |
|
| 2003 |
Radu A, Neubauer V, Akagi T, Hanafusa H, Georgescu MM. PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. Molecular and Cellular Biology. 23: 6139-49. PMID 12917336 DOI: 10.1128/Mcb.23.17.6139-6149.2003 |
0.365 |
|
| 2001 |
Kirsch KH, Georgescu MM, Shishido T, Langdon WY, Birge RB, Hanafusa H. The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction. The Journal of Biological Chemistry. 276: 4957-63. PMID 11067845 DOI: 10.1074/Jbc.M005784200 |
0.317 |
|
| 2000 |
Georgescu MM, Kirsch KH, Kaloudis P, Yang H, Pavletich NP, Hanafusa H. Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor. Cancer Research. 60: 7033-8. PMID 11156408 |
0.321 |
|
| 2000 |
Shishido T, Akagi T, Ouchi T, Georgescu MM, Langdon WY, Hanafusa H. The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 97: 6439-44. PMID 10829062 DOI: 10.1073/Pnas.060030697 |
0.302 |
|
| 1999 |
Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell. 99: 323-34. PMID 10555148 DOI: 10.1016/S0092-8674(00)81663-3 |
0.408 |
|
| 1999 |
Georgescu MM, Kirsch KH, Akagi T, Shishido T, Hanafusa H. The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proceedings of the National Academy of Sciences of the United States of America. 96: 10182-7. PMID 10468583 DOI: 10.1073/Pnas.96.18.10182 |
0.412 |
|
| 1999 |
Kirsch KH, Georgescu MM, Ishimaru S, Hanafusa H. CMS: an adapter molecule involved in cytoskeletal rearrangements. Proceedings of the National Academy of Sciences of the United States of America. 96: 6211-6. PMID 10339567 DOI: 10.1073/Pnas.96.11.6211 |
0.307 |
|
| 1999 |
Georgescu MM, Kirsch KH, Shishido T, Zong C, Hanafusa H. Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB. Molecular and Cellular Biology. 19: 1171-81. PMID 9891051 DOI: 10.1128/Mcb.19.2.1171 |
0.309 |
|
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