Ethan Royal Signer - Publications

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, ... Signer E, et al. Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease. Science Translational Medicine. 6: 268ra178. PMID 25540325 DOI: 10.1126/scitranslmed.3010523  1
2014 Signer E. Through postdoc eyes Research in Microbiology. 165: 346-347. PMID 24859142 DOI: 10.1016/j.resmic.2014.05.029  1
2010 Menalled LB, Patry M, Ragland N, Lowden PA, Goodman J, Minnich J, Zahasky B, Park L, Leeds J, Howland D, Signer E, Tobin AJ, Brunner D. Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. Plos One. 5: e9793. PMID 20339553 DOI: 10.1371/journal.pone.0009793  1
2009 Menalled L, El-Khodor BF, Patry M, Suárez-Fariñas M, Orenstein SJ, Zahasky B, Leahy C, Wheeler V, Yang XW, MacDonald M, Morton AJ, Bates G, Leeds J, Park L, Howland D, ... Signer E, et al. Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models. Neurobiology of Disease. 35: 319-36. PMID 19464370 DOI: 10.1016/j.nbd.2009.05.007  1
2001 Xiaohui Wang H, Viret JF, Eldridge A, Perera R, Signer ER, Chiurazzi M. Positive-negative selection for homologous recombination in Arabidopsis. Gene. 272: 249-55. PMID 11470531 DOI: 10.1016/S0378-1119(01)00532-7  1
2000 Tobin AJ, Signer ER. Huntington's disease: the challenge for cell biologists. Trends in Cell Biology. 10: 531-6. PMID 11121745 DOI: 10.1016/S0962-8924(00)01853-5  1
1996 Chiurazzi M, Ray A, Viret JF, Perera R, Wang XH, Lloyd AM, Signer ER. Enhancement of somatic intrachromosomal homologous recombination in Arabidopsis by the HO endonuclease. The Plant Cell. 8: 2057-66. PMID 8953770 DOI: 10.1105/tpc.8.11.2057  1
1996 Ye F, Signer ER. RIGS (repeat-induced gene silencing) in Arabidopsis is transcriptional and alters chromatin configuration. Proceedings of the National Academy of Sciences of the United States of America. 93: 10881-6. PMID 8855276 DOI: 10.1073/pnas.93.20.10881  1
1995 Sonti RV, Chiurazzi M, Wong D, Davies CS, Harlow GR, Mount DW, Signer ER. Arabidopsis mutants deficient in T-DNA integration. Proceedings of the National Academy of Sciences of the United States of America. 92: 11786-90. PMID 8524849 DOI: 10.1073/pnas.92.25.11786  1
1995 Tissier AF, Lopez MF, Signer ER. Purification and characterization of a DNA strand transferase from broccoli. Plant Physiology. 108: 379-86. PMID 7784508  1
1995 Sonti RV, Tissier AF, Wong D, Viret JF, Signer ER. Activity of the yeast FLP recombinase in Arabidopsis. Plant Molecular Biology. 28: 1127-32. PMID 7548830 DOI: 10.1007/BF00032673  1
1994 Chiurazzi M, Signer ER. Termini and telomeres in T-DNA transformation. Plant Molecular Biology. 26: 923-34. PMID 8000005 DOI: 10.1007/BF00028859  1
1994 Leach F, Wacks DB, Signer ER. Rhizobium meliloti homologs of Escherichia coli mur genes. Gene. 148: 87-90. PMID 7926844 DOI: 10.1016/0378-1119(94)90238-0  1
1994 Chaudhury AM, Craig S, Dennis ES, Lavithis M, Taylor PE, Singh MB, Knox RB, Signer ER. Genetic control of male fertility in Arabidopsis thaliana: structural analysis of premeiotic developmental mutants Sexual Plant Reproduction. 7: 17-28. DOI: 10.1007/BF00241884  1
1993 Assaad FF, Tucker KL, Signer ER. Epigenetic repeat-induced gene silencing (RIGS) in Arabidopsis. Plant Molecular Biology. 22: 1067-85. PMID 8400126 DOI: 10.1007/BF00028978  1
1993 Perera RJ, Linard CG, Signer ER. Cytosine deaminase as a negative selective marker for Arabidopsis. Plant Molecular Biology. 23: 793-9. PMID 8251632 DOI: 10.1007/BF00021534  1
1992 Kieber JJ, Tissier AF, Signer ER. Cloning and Characterization of an Arabidopsis thaliana Topoisomerase I Gene. Plant Physiology. 99: 1493-501. PMID 16669064  1
1992 Yang C, Signer ER, Hirsch AM. Nodules Initiated by Rhizobium meliloti Exopolysaccharide Mutants Lack a Discrete, Persistent Nodule Meristem. Plant Physiology. 98: 143-51. PMID 16668605  1
1992 Assaad FF, Signer ER. Somatic and germinal recombination of a direct repeat in Arabidopsis. Genetics. 132: 553-66. PMID 1330826  1
1992 Kieber JJ, Lopez MF, Tissier AF, Signer E. Purification and properties of DNA topoisomerase I from broccoli Plant Molecular Biology. 18: 865-871. PMID 1316191 DOI: 10.1007/BF00019201  1
1992 Klein S, Lohman K, Clover R, Walker GC, Signer ER. A directional, high-frequency chromosomal mobilization system for genetic mapping of Rhizobium meliloti. Journal of Bacteriology. 174: 324-6. PMID 1309521  1
1991 Brzoska PM, Signer ER. lpsZ, a lipopolysaccharide gene involved in symbiosis of Rhizobium meliloti. Journal of Bacteriology. 173: 3235-7. PMID 2022621  1
1991 Kieber JJ, Signer ER. Cloning and characterization of an inorganic pyrophosphatase gene from Arabidopsis thaliana. Plant Molecular Biology. 16: 345-8. PMID 1654155 DOI: 10.1007/BF00020567  1
1990 Williams MN, Signer ER. Metabolism of Tryptophan and Tryptophan Analogs by Rhizobium meliloti. Plant Physiology. 92: 1009-13. PMID 16667364  1
1990 Williams MN, Hollingsworth RI, Brzoska PM, Signer ER. Rhizobium meliloti chromosomal loci required for suppression of exopolysaccharide mutations by lipopolysaccharide. Journal of Bacteriology. 172: 6596-8. PMID 2228976  1
1990 Assaad FF, Signer ER. Cauliflower mosaic virus P35S promoter activity in Escherichia coli. Molecular & General Genetics : Mgg. 223: 517-20. PMID 2176717 DOI: 10.1007/BF00264462  1
1990 Sharma SB, Signer ER. Temporal and spatial regulation of the symbiotic genes of Rhizobium meliloti in planta revealed by transposon Tn5-gusA. Genes & Development. 4: 344-56. PMID 2159937  1
1990 Williams MN, Hollingsworth RI, Klein S, Signer ER. The symbiotic defect of Rhizobium meliloti exopolysaccharide mutants is suppressed by lpsZ+, a gene involved in lipopolysaccharide biosynthesis. Journal of Bacteriology. 172: 2622-32. PMID 2158975  1
1990 Bent AF, Signer ER. Rhizobium meliloti suhR suppresses the phenotype of an Escherichia coli RNA polymerase sigma 32 mutant. Journal of Bacteriology. 172: 3559-68. PMID 2113906  1
1990 Signer E, Beckwith J. Cloning with φ80lac: The French connection Bioessays. 12: 503-507. PMID 2082941  1
1990 Fox MS, Magasanik B, Signer ER, Solomon F, Gellert MF, Haber JE. The genome project: Pro and con (I) Science. 247: 270.  1
1989 Chaudhury AM, Signer ER. Relative regeneration proficiency ofArabidopsis thaliana ecotypes. Plant Cell Reports. 8: 368-9. PMID 24233278 DOI: 10.1007/BF00716676  1
1989 Williams MN, Klein S, Signer ER. Host Restriction and Transduction in Rhizobium meliloti. Applied and Environmental Microbiology. 55: 3229-30. PMID 16348079  1
1989 Clover RH, Kieber J, Signer ER. Lipopolysaccharide mutants of Rhizobium meliloti are not defective in symbiosis. Journal of Bacteriology. 171: 3961-7. PMID 2738026  1
1989 Chaudhury AM, Signer ER. Non-destructive transformation of Arabidopsis Plant Molecular Biology Reporter. 7: 258-265. DOI: 10.1007/BF02668634  1
1988 Klein S, Walker GC, Signer ER. All nod genes of Rhizobium meliloti are involved in alfalfa nodulation by exo mutants. Journal of Bacteriology. 170: 1003-6. PMID 3338972  1
1988 Michiels KW, Vanderleyden J, Van Gool AP, Signer ER. Isolation and characterization of Azospirillum brasilense loci that correct Rhizobium meliloti exoB and exoC mutations. Journal of Bacteriology. 170: 5401-4. PMID 3182731  1
1988 Klein S, Hirsch AM, Smith CA, Signer ER. Interaction of nod and exo Rhizobium meliloti in alfalfa nodulation. Molecular Plant-Microbe Interactions : Mpmi. 1: 94-100. PMID 2979704  1
1986 De Vos GF, Walker GC, Signer ER. Genetic manipulations in Rhizobium meliloti utilizing two new transposon Tn5 derivatives. Molecular & General Genetics : Mgg. 204: 485-91. PMID 3020382 DOI: 10.1007/BF00331029  1
1986 Finan TM, Kunkel B, De Vos GF, Signer ER. Second symbiotic megaplasmid in Rhizobium meliloti carrying exopolysaccharide and thiamine synthesis genes. Journal of Bacteriology. 167: 66-72. PMID 3013840  1
1985 Leigh JA, Signer ER, Walker GC. Exopolysaccharide-deficient mutants of Rhizobium meliloti that form ineffective nodules. Proceedings of the National Academy of Sciences of the United States of America. 82: 6231-5. PMID 3862129  1
1985 Finan TM, Hirsch AM, Leigh JA, Johansen E, Kuldau GA, Deegan S, Walker GC, Signer ER. Symbiotic mutants of Rhizobium meliloti that uncouple plant from bacterial differentiation. Cell. 40: 869-77. PMID 2985267 DOI: 10.1016/0092-8674(85)90346-0  1
1984 Johansen E, Finan TM, Gefter ML, Signer ER. Monoclonal antibodies to Rhizobium meliloti and surface mutants insensitive to them. Journal of Bacteriology. 160: 454-7. PMID 6480561  1
1984 De Vos GF, Finan TM, Signer ER, Walker GC. Host-dependent transposon Tn5-mediated streptomycin resistance. Journal of Bacteriology. 159: 395-9. PMID 6330042  1
1984 Finan TM, Hartweig E, LeMieux K, Bergman K, Walker GC, Signer ER. General transduction in Rhizobium meliloti. Journal of Bacteriology. 159: 120-4. PMID 6330024  1
1982 Raleigh EA, Signer ER. Positive selection of nodulation-deficient Rhizobium phaseoli. Journal of Bacteriology. 151: 83-8. PMID 7085572  1
1981 Sanders R, Raleigh E, Signer E. Lack of correlation between extracellular polysaccharide and nodulation ability in Rhizobium Nature. 292: 148-149.  1
1980 Osburne MS, Signer ER. Ammonium assimilation in Rhizobium meliloti. Journal of Bacteriology. 143: 1234-40. PMID 6106011  1
1979 Ludwig RA, Raleigh EA, Duncan MJ, Signer ER, Gibson AH, Dudman WF, Schwinghamer EA, Jordan DC, Schmidt EL, Tran DT. Further examination of presumptive Rhizobium trifolii mutants that nodulate Glycine max. Proceedings of the National Academy of Sciences of the United States of America. 76: 3942-6. PMID 16592695  1
1978 Ucker DS, Signer ER. Catabolite-repression-like phenomenon in Rhizobium meliloti. Journal of Bacteriology. 136: 1197-200. PMID 214420  1
1977 Kleckner N, Signer ER. Genetic characterization of plasmid formation by N- mutants of bacteriophage lambda. Virology. 79: 160-73. PMID 325881 DOI: 10.1016/0042-6822(77)90342-7  1
1977 Meade HM, Signer ER. Genetic mapping of Rhizobium meliloti. Proceedings of the National Academy of Sciences of the United States of America. 74: 2076-8. PMID 266730  1
1977 Ludwig RA, Signer ER. Glutamine synthetase control of nitrogen fixation in Rhizobia. Basic Life Sciences. 9: 419-20. PMID 21651  1
1977 Ludwig RA, Signer ER. Glutamine synthetase and control of nitrogen fixation in Rhizobium. Nature. 267: 245-8. PMID 17073  1
1975 Mertz JE, Signer ER, Schaefer F. Amber red- mutants of phage lambda. Virology. 63: 591-5. PMID 1114701 DOI: 10.1016/0042-6822(75)90332-3  1
1974 Herskowitz I, Signer ER. Substitution mutation in bacteriophage lambda with new specificity for late gene expression. Virology. 61: 112-9. PMID 4415976 DOI: 10.1016/0042-6822(74)90246-3  1
1971 Rybtchine VN, Signer ER. Genetic changes within prophage phi 80 correlated with exchanges between Lost markers on either side. Virology. 45: 503-7. PMID 4937996 DOI: 10.1016/0042-6822(71)90350-3  1
1970 Miller JH, Reznikoff WS, Silverstone AE, Ippen K, Signer ER, Beckwith JR. Fusions of the lac and trp Regions of the Escherichia coli Chromosome. Journal of Bacteriology. 104: 1273-9. PMID 16559103  1
1970 Signer ER. On the control of lysogeny in phage lambda. Virology. 40: 624-33. PMID 5437788 DOI: 10.1016/0042-6822(70)90207-2  1
1970 Herskowitz I, Signer ER. A site essential for expression of all late genes in bacteriophage lambda. Journal of Molecular Biology. 47: 545-56. PMID 5418171 DOI: 10.1016/0022-2836(70)90321-9  1
1970 Shulman MJ, Hallick LM, Echols H, Signer ER. Properties of recombination-deficient mutants of bacteriophage lambda. Journal of Molecular Biology. 52: 501-20. PMID 4923748 DOI: 10.1016/0022-2836(70)90416-X  1
1969 Signer ER, Manly KF, Brunstetter MA. Deletion mapping of the c-3-N region of bacteriophage. Virology. 39: 137-41. PMID 5812352  1
1969 Signer ER. Plasmid formation: a new mode of lysogeny by phase lambda. Nature. 223: 158-60. PMID 5791722 DOI: 10.1038/223158a0  1
1969 Manly KF, Signer ER, Radding CM. Nonessential functions of bacteriophage lambda. Virology. 37: 177-88. PMID 4974326  1
1969 Signer ER, Weil J, Kimball PC. Recombination in bacteriophage lambda. 3. Studies on the nature of the prophage attachment region. Journal of Molecular Biology. 46: 543-63. PMID 4904107  1
1969 Signer ER, Manly KF, Brunstetter MA. Deletion mapping of the cIII-N region of bacteriophage λ Virology. 39: 137-141.  1
1969 Manly KF, Signer ER, Radding CM. Nonessential functions of bacteriophage λ Virology. 37: 177-188.  1
1968 Weil J, Signer ER. Recombination in bacteriophage lambda. II. Site-specific recombination promoted by the integration system. Journal of Molecular Biology. 34: 273-9. PMID 5760459  1
1968 Signer ER, Weil J. Recombination in bacteriophage lambda. I. Mutants deficient in general recombination. Journal of Molecular Biology. 34: 261-71. PMID 5760458  1
1968 Signer ER, Weil J. Site-specific recombination in bacteriophage lambda. Cold Spring Harbor Symposia On Quantitative Biology. 33: 715-9. PMID 5254580  1
1968 Signer E, Echols H, Weil J, Radding C, Shulman M, Moore L, Manly K. The general recombination system of bacteriophage lambda. Cold Spring Harbor Symposia On Quantitative Biology. 33: 711-4. PMID 5254579  1
1968 Signer ER. Lysogeny: the integration problem. Annual Review of Microbiology. 22: 451-88. PMID 4879520 DOI: 10.1146/annurev.mi.22.100168.002315  1
1967 Signer ER. A plaque assay for lambda attachment. Virology. 33: 352-4. PMID 4167869  1
1966 Fox CF, Beckwith JR, Epstein W, Signer ER. Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism. Journal of Molecular Biology. 19: 576-9. PMID 5338859  1
1966 Beckwith JR, Signer ER. Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80. Journal of Molecular Biology. 19: 254-65. PMID 5338856  1
1966 Signer ER. Interaction of prophages at the att80 site with the chromosome of Escherichia coli. Journal of Molecular Biology. 15: 243-55. PMID 5330218  1
1966 Beckwith JR, Signer ER, Epstein W. Transposition of the Lac region of E. coli. Cold Spring Harbor Symposia On Quantitative Biology. 31: 393-401. PMID 4866389  1
1966 Signer ER, Beckwith JR. Transposition of the lac region of Escherichia coli. III. The mechanism of attachment of bacteriophage φ80 to the bacterial chromosome Journal of Molecular Biology. 22: 33-51.  1
1965 SIGNER ER. GENE EXPRESSION IN FOREIGN CYTOPLASM. Journal of Molecular Biology. 12: 1-8. PMID 14343280  1
1965 Signer ER. Attachment specificity of prophage lambda-dg. Journal of Molecular Biology. 14: 582-5. PMID 5880866  1
1965 Signer ER, Beckwith JR, Brenner S. Mapping of suppressor loci in Escherichia coli. Journal of Molecular Biology. 14: 153-66. PMID 5327649  1
1964 SIGNER ER. RECOMBINATION BETWEEN COLIPHAGES LAMBDA AND PHI-80. Virology. 22: 650-1. PMID 14166126  1
1962 LEVINTHAL C, SIGNER ER, FETHEROLF K. Reactivation and hybridization of reduced alkaline phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 48: 1230-7. PMID 14464689  1
1961 SIGNER ER, TORRIANI A, LEVINTHAL C. Gene expression in intergeneric merozygotes. Cold Spring Harbor Symposia On Quantitative Biology. 26: 31-4. PMID 13912734  1
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