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Chad A. Lerner, Ph.D. - Publications

Affiliations: 
2012 Pathology Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Genetics
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20/39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Labbé K, Mookerjee S, Le Vasseur M, Gibbs E, Lerner C, Nunnari J. The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis. The Journal of Cell Biology. 220. PMID 34586346 DOI: 10.1083/jcb.202103122  0.307
2016 Lerner CA, Lei W, Sundar IK, Rahman I. Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury. Frontiers in Pharmacology. 7: 391. PMID 27826243 DOI: 10.3389/Fphar.2016.00391  0.32
2016 Ahmad T, Sundar IK, Tormos AM, Lerner CA, Gerloff J, Yao H, Rahman I. Shelterin TPP1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirt1 Deacetylase in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory Cell and Molecular Biology. PMID 27559927 DOI: 10.1165/Rcmb.2016-0198Oc  0.345
2016 Lerner CA, Sundar IK, Rahman I. Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD. The International Journal of Biochemistry & Cell Biology. PMID 27474491 DOI: 10.1016/J.Biocel.2016.07.026  0.421
2016 Lerner CA, Rutagarama P, Ahmad T, Sundar IK, Elder A, Rahman I. Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts. Biochemical and Biophysical Research Communications. PMID 27343559 DOI: 10.1016/J.Bbrc.2016.06.109  0.367
2015 Ahmad T, Sundar IK, Lerner CA, Gerloff J, Tormos AM, Yao H, Rahman I. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2912-29. PMID 25792665 DOI: 10.1096/Fj.14-268276  0.37
2015 Salmon AB, Lerner C, Ikeno Y, Motch Perrine SM, McCarter R, Sell C. Altered metabolism and resistance to obesity in long-lived mice producing reduced levels of IGF-I. American Journal of Physiology. Endocrinology and Metabolism. 308: E545-53. PMID 25648834 DOI: 10.1152/Ajpendo.00558.2014  0.513
2014 Crowe EP, Nacarelli T, Bitto A, Lerner C, Sell C, Torres C. Detecting senescence: methods and approaches. Methods in Molecular Biology (Clifton, N.J.). 1170: 425-45. PMID 24906328 DOI: 10.1007/978-1-4939-0888-2_23  0.612
2014 Bitto A, Crowe EP, Lerner C, Torres C, Sell C. The senescence arrest program and the cell cycle. Methods in Molecular Biology (Clifton, N.J.). 1170: 145-54. PMID 24906313 DOI: 10.1007/978-1-4939-0888-2_8  0.645
2014 Bitto A, Lerner CA, Nacarelli T, Crowe E, Torres C, Sell C. P62/SQSTM1 at the interface of aging, autophagy, and disease. Age (Dordrecht, Netherlands). 36: 9626. PMID 24557832 DOI: 10.1007/S11357-014-9626-3  0.638
2014 Lorenzini A, Salmon AB, Lerner C, Torres C, Ikeno Y, Motch S, McCarter R, Sell C. Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: 410-9. PMID 23873963 DOI: 10.1093/Gerona/Glt108  0.525
2013 Lerner C, Bitto A, Pulliam D, Nacarelli T, Konigsberg M, Van Remmen H, Torres C, Sell C. Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell. 12: 966-77. PMID 23795962 DOI: 10.1111/Acel.12122  0.677
2013 Pirrone V, Libon DJ, Sell C, Lerner CA, Nonnemacher MR, Wigdahl B. Impact of age on markers of HIV-1 disease. Future Virology. 8: 81-101. PMID 23596462 DOI: 10.2217/Fvl.12.127  0.493
2013 Bitto A, Lerner CA, Van Remmen H, Konigsberg M, Pulliam D, Torres C, Sell C. Rapamycin improves mitochondrial homeostasis and delays the onset of senescence by altering p62/SQSTM1 dynamics Experimental Gerontology. 48: 692-693. DOI: 10.1016/J.Exger.2013.05.035  0.629
2013 Lerner C, Bitto A, Torres C, Sell C. Enhanced autophagy drives coordinate expression in nuclear and mitochondrial genomes Experimental Gerontology. 48: 686. DOI: 10.1016/J.Exger.2013.05.015  0.647
2011 Fink LS, Roell M, Caiazza E, Lerner C, Stamato T, Hrelia S, Lorenzini A, Sell C. 53BP1 contributes to a robust genomic stability in human fibroblasts. Aging. 3: 836-45. PMID 21931182  0.677
2011 Lerner C, Bitto A, Torres C, Sell C. IGF-I deficient mice show enhanced autophagy and increased mitochondrial content Experimental Gerontology. 46: 211-212. DOI: 10.1016/J.Exger.2010.11.023  0.664
2011 Bitto A, Lerner CA, Perez VE, Torres C, Sell C. IGF-I signaling affects long-term viability of primary human fibroblasts by impairing mitophagy of dysfunctional mitochondria Experimental Gerontology. 46: 209. DOI: 10.1016/J.Exger.2010.11.016  0.644
2010 Fink LS, Lerner CA, Torres PF, Sell C. Ku80 facilitates chromatin binding of the telomere binding protein, TRF2. Cell Cycle (Georgetown, Tex.). 9: 3798-806. PMID 20890109 DOI: 10.4161/Cc.9.18.13129  0.67
2010 Bitto A, Lerner C, Torres C, Roell M, Malaguti M, Perez V, Lorenzini A, Hrelia S, Ikeno Y, Matzko ME, McCarter R, Sell C. Long-term IGF-I exposure decreases autophagy and cell viability. Plos One. 5: e12592. PMID 20830296 DOI: 10.1371/Journal.Pone.0012592  0.683
Low-probability matches (unlikely to be authored by this person)
2017 Lei W, Lerner C, Sundar IK, Rahman I. Myofibroblast differentiation and its functional properties are inhibited by nicotine and e-cigarette via mitochondrial OXPHOS complex III. Scientific Reports. 7: 43213. PMID 28256533 DOI: 10.1038/Srep43213  0.287
2022 Boutoual R, Jo H, Heckenbach I, Tiwari R, Kasler H, Lerner CA, Shah S, Schilling B, Calvanese V, Rardin MJ, Scheibye-Knudsen M, Verdin E. A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function. Scientific Reports. 12: 14804. PMID 36045139 DOI: 10.1038/s41598-022-18114-x  0.282
2014 Yao H, Sundar IK, Ahmad T, Lerner C, Gerloff J, Friedman AE, Phipps RP, Sime PJ, McBurney MW, Guarente L, Rahman I. SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L816-28. PMID 24633890 DOI: 10.1152/Ajplung.00323.2013  0.278
2015 Lerner CA, Sundar IK, Yao H, Gerloff J, Ossip DJ, McIntosh S, Robinson R, Rahman I. Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung. Plos One. 10: e0116732. PMID 25658421 DOI: 10.1371/Journal.Pone.0116732  0.268
2015 Lerner CA, Sundar IK, Watson RM, Elder A, Jones R, Done D, Kurtzman R, Ossip DJ, Robinson R, McIntosh S, Rahman I. Environmental health hazards of e-cigarettes and their components: Oxidants and copper in e-cigarette aerosols. Environmental Pollution (Barking, Essex : 1987). 198: 100-7. PMID 25577651 DOI: 10.1016/J.Envpol.2014.12.033  0.213
2004 Trounce IA, McKenzie M, Cassar CA, Ingraham CA, Lerner CA, Dunn DA, Donegan CL, Takeda K, Pogozelski WK, Howell RL, Pinkert CA. Development and initial characterization of xenomitochondrial mice Journal of Bioenergetics and Biomembranes. 36: 421-427. PMID 15377882 DOI: 10.1023/B:JOBB.0000041778.84464.16  0.204
2022 Lerner CA, Gerencser AA. Unbiased Millivolts Assay of Mitochondrial Membrane Potential in Intact Cells. Methods in Molecular Biology (Clifton, N.J.). 2497: 11-61. PMID 35771433 DOI: 10.1007/978-1-0716-2309-1_2  0.191
2023 Neri F, Takajjart SN, Lerner CA, Desprez PY, Schilling B, Campisi J, Gerencser AA. A Fully-Automated Senescence Test (FAST) for the high-throughput quantification of senescence-associated markers. Biorxiv : the Preprint Server For Biology. PMID 38187756 DOI: 10.1101/2023.12.22.573123  0.17
2020 Louie MC, Ton J, Brady ML, Le DT, Mar JN, Lerner CA, Gerencser AA, Mookerjee SA. Total Cellular ATP Production Changes With Primary Substrate in MCF7 Breast Cancer Cells. Frontiers in Oncology. 10: 1703. PMID 33224868 DOI: 10.3389/fonc.2020.01703  0.142
2022 Gibbs Ii ET, Lerner CA, Watson MA, Wong HS, Gerencser AA, Brand MD. Site IQ in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions. The Biochemical Journal. PMID 36862427 DOI: 10.1042/BCJ20220611  0.109
1989 Wallis JW, Miller TR, Lerner CA, Kleerup EC. Three-Dimensional Display in Nuclear Medicine Ieee Transactions On Medical Imaging. 8: 297-303. DOI: 10.1109/42.41482  0.067
1993 Stein MA, Lerner CA. Behavioral and cognitive effect of theophylline: A dose-response study Annals of Allergy. 70: 135-140. PMID 8430921  0.036
1997 Lerner CA, Dang H, Kutilek RA. Strangulated traumatic diaphragmatic hernia simulating a subphrenic abscess Journal of Emergency Medicine. 15: 849-853. PMID 9404803 DOI: 10.1016/S0736-4679(97)00192-3  0.023
1998 Poage DP, Lerner CA. Absence of chemical shift artifact on coronal T1-weighted MR images: An undescribed finding seen in osteochondral injuries of the knee in 12 patients American Journal of Roentgenology. 171: 1521-1523. PMID 9843282  0.018
1998 Lerner C. Detecting acute extraaxial blood with bone algorithm CT images. Ajr. American Journal of Roentgenology. 171: 1707. PMID 9843321 DOI: 10.2214/ajr.171.6.9843321  0.016
1997 Lerner CA. A simple teaching aid for MR physics Ajr. American Journal of Roentgenology. 169: 1193-1194. PMID 9308491  0.01
1997 Lerner CA, Dang HP. MR imaging of a pericardial gossypiboma [2] American Journal of Roentgenology. 169: 314. PMID 9207567 DOI: 10.2214/ajr.169.1.9207567  0.01
1997 Stafford Johnson DB, Lerner CA, Prince MR, Kazanjian SN, Narasimham DL, Leichtman AB, Cho KJ. Gadolinium-enhanced magnetic resonance angiography of renal transplants Magnetic Resonance Imaging. 15: 13-20. PMID 9084020 DOI: 10.1016/S0730-725X(96)00348-7  0.01
1993 Lerner CA, Prager JM. THREE-DIMENSIONAL CT MYELOGRAPHY Investigative Radiology. 28: 1197. DOI: 10.1097/00004424-199312000-00091  0.01
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