Matthew R. Skelton, Ph.D. - Publications

Affiliations: 
2006 University of Cincinnati, Cincinnati, OH 
Area:
Neuroscience Biology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Abdulla ZI, Pennington JL, Gutierrez A, Skelton MR. Creatine transporter knockout mice (Slc6a8) show increases in serotonin-related proteins and are resilient to learned helplessness. Behavioural Brain Research. 112254. PMID 31542396 DOI: 10.1016/j.bbr.2019.112254  0.48
2019 Abdulla ZI, Pahlevani B, Lundgren KH, Pennington JL, Udobi KC, Seroogy KB, Skelton MR. Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice. Journal of Molecular Neuroscience : Mn. PMID 31520365 DOI: 10.1007/s12031-019-01405-w  0.96
2019 Udobi KC, Delcimmuto N, Kokenge AN, Abdulla ZI, Perna MK, Skelton MR. Deletion of the creatine transporter gene in neonatal, but not adult, mice lead to cognitive deficits. Journal of Inherited Metabolic Disease. PMID 31209903 DOI: 10.1002/jimd.12137  0.96
2019 Ullio-Gamboa G, Udobi KC, Dezard S, Perna MK, Miles KN, Costa N, Taran F, Pruvost A, Benoit JP, Skelton MR, Lonlay P, Mabondzo A. Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency. Nanomedicine (London, England). PMID 31038003 DOI: 10.2217/nnm-2019-0059  0.96
2018 Bermúdez ML, Skelton MR, Genter MB. Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease. Molecular Genetics and Metabolism. PMID 30146452 DOI: 10.1016/j.ymgme.2018.08.002  0.48
2018 Udobi KC, Kokenge AN, Hautman ER, Ullio G, Coene J, Williams MT, Vorhees CV, Mabondzo A, Skelton MR. Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8. Genes, Brain, and Behavior. PMID 29384270 DOI: 10.1111/gbb.12461  0.96
2017 Hufgard JR, Williams MT, Skelton MR, Grubisha O, Ferreira FM, Sanger H, Wright ME, Reed-Kessler TM, Rasmussen K, Duman RS, Vorhees CV. Phosphodiesterase-1b (Pde1b) knockout mice are resistant to forced swim and tail suspension induced immobility and show upregulation of Pde10a. Psychopharmacology. PMID 28337525 DOI: 10.1007/s00213-017-4587-8  0.96
2016 Amos-Kroohs RM, Davenport LL, Atanasova N, Abdulla ZI, Skelton MR, Vorhees CV, Williams MT. Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory. Neurotoxicology and Teratology. PMID 27756629 DOI: 10.1016/j.ntt.2016.10.005  0.96
2016 Stottmann RW, Driver A, Gutierrez A, Skelton MR, Muntifering M, Stepien C, Knudson L, Kofron M, Vorhees CV, Williams MT. A HETEROZYGOUS MUTATION IN TUBULIN, BETA 2B (TUBB2B) CAUSES COGNITIVE DEFICITS AND HIPPOCAMPAL DISORGANIZATION. Genes, Brain, and Behavior. PMID 27594048 DOI: 10.1111/gbb.12327  0.96
2016 Perna MK, Kokenge AN, Miles KN, Udobi KC, Clark JF, Pyne-Geithman GJ, Khuchua Z, Skelton MR. Creatine transporter deficiency leads to increased whole body and cellular metabolism. Amino Acids. PMID 27401086 DOI: 10.1007/s00726-016-2291-3  0.96
2016 Amos-Kroohs RM, Graham DL, Grace CE, Braun AA, Schaefer TL, Skelton MR, Vorhees CV, Williams MT. Developmental stress and lead (Pb): Effects of maternal separation and/or Pb on corticosterone, monoamines, and blood Pb in rats. Neurotoxicology. PMID 26943976 DOI: 10.1016/j.neuro.2016.02.011  0.96
2015 Braun AA, Amos-Kroohs RM, Gutierrez A, Lundgren KH, Seroogy KB, Skelton MR, Vorhees CV, Williams MT. Dopamine depletion in either the dorsomedial or dorsolateral striatum impairs egocentric Cincinnati water maze performance while sparing allocentric Morris water maze learning. Neurobiology of Learning and Memory. 118: 55-63. PMID 25451306 DOI: 10.1016/j.nlm.2014.10.009  0.96
2015 Vorhees CV, Graham DL, Braun AA, Schaefer TL, Skelton MR, Richtand NM, Williams MT. Prenatal immune challenge in rats: effects of polyinosinic-polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine. Neurotoxicology and Teratology. 47: 54-65. PMID 25450663 DOI: 10.1016/j.ntt.2014.10.007  0.96
2014 Vorhees CV, Graham DL, Amos-Kroohs RM, Braun AA, Grace CE, Schaefer TL, Skelton MR, Erikson KM, Aschner M, Williams MT. Effects of developmental manganese, stress, and the combination of both on monoamines, growth, and corticosterone. Toxicology Reports. 1: 1046-1061. PMID 25574457 DOI: 10.1016/j.toxrep.2014.10.004  0.96
2014 Williams MT, Skelton MR, Longacre ID, Huggins KN, Maple AM, Vorhees CV, Brown RW. Neuronal reorganization in adult rats neonatally exposed to (±)-3,4-methylenedioxymethamphetamine. Toxicology Reports. 1: 699-706. PMID 25419515 DOI: 10.1016/j.toxrep.2014.08.018  0.96
2014 Russell AP, Ghobrial L, Wright CR, Lamon S, Brown EL, Kon M, Skelton MR, Snow RJ. Creatine transporter (SLC6A8) knockout mice display an increased capacity for in vitro creatine biosynthesis in skeletal muscle. Frontiers in Physiology. 5: 314. PMID 25206338 DOI: 10.3389/fphys.2014.00314  0.96
2014 Hautman ER, Kokenge AN, Udobi KC, Williams MT, Vorhees CV, Skelton MR. Female mice heterozygous for creatine transporter deficiency show moderate cognitive deficits. Journal of Inherited Metabolic Disease. 37: 63-8. PMID 23716276 DOI: 10.1007/s10545-013-9619-x  0.96
2013 Schaefer TL, Grace CE, Braun AA, Amos-Kroohs RM, Graham DL, Skelton MR, Williams MT, Vorhees CV. Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1383-94. PMID 23308402 DOI: 10.1017/S1461145712001447  0.96
2013 Graham DL, Amos-Kroohs RM, Braun AA, Grace CE, Schaefer TL, Skelton MR, Williams MT, Vorhees CV. Neonatal +-methamphetamine exposure in rats alters adult locomotor responses to dopamine D1 and D2 agonists and to a glutamate NMDA receptor antagonist, but not to serotonin agonists. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 377-91. PMID 22391043 DOI: 10.1017/S1461145712000144  0.96
2012 Schaefer TL, Grace CE, Skelton MR, Graham DL, Gudelsky GA, Vorhees CV, Williams MT. Neonatal citalopram treatment inhibits the 5-HT depleting effects of MDMA exposure in rats. Acs Chemical Neuroscience. 3: 12-21. PMID 22582138 DOI: 10.1021/cn2000553  0.96
2012 Vorhees CV, Graham DL, Braun AA, Schaefer TL, Skelton MR, Richtand NM, Williams MT. Prenatal immune challenge in rats: altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC. Synapse (New York, N.Y.). 66: 725-37. PMID 22473973 DOI: 10.1002/syn.21561  0.96
2012 Wong AC, Velamoor S, Skelton MR, Thorne PR, Vlajkovic SM. Expression and distribution of creatine transporter and creatine kinase (brain isoform) in developing and mature rat cochlear tissues. Histochemistry and Cell Biology. 137: 599-613. PMID 22307408 DOI: 10.1007/s00418-012-0922-7  0.96
2012 Skelton MR, Graham DL, Schaefer TL, Grace CE, Braun AA, Burns LN, Amos-Kroohs RM, Williams MT, Vorhees CV. Distinct periods of developmental sensitivity to the effects of 3,4-(±)-methylenedioxymethamphetamine (MDMA) on behaviour and monoamines in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 811-24. PMID 21733225 DOI: 10.1017/S1461145711000952  0.96
2011 Vorhees CV, Morford LR, Graham DL, Skelton MR, Williams MT. Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug. Behavioral and Brain Functions : Bbf. 7: 41. PMID 21974752 DOI: 10.1186/1744-9081-7-41  0.96
2011 Curran CP, Nebert DW, Genter MB, Patel KV, Schaefer TL, Skelton MR, Williams MT, Vorhees CV. In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes. Environmental Health Perspectives. 119: 1286-93. PMID 21571617 DOI: 10.1289/ehp.1002965  0.96
2011 Skelton MR, Schaefer TL, Graham DL, Degrauw TJ, Clark JF, Williams MT, Vorhees CV. Creatine transporter (CrT; Slc6a8) knockout mice as a model of human CrT deficiency. Plos One. 6: e16187. PMID 21249153 DOI: 10.1371/journal.pone.0016187  0.96
2011 Graham DL, Grace CE, Braun AA, Schaefer TL, Skelton MR, Tang PH, Vorhees CV, Williams MT. Effects of developmental stress and lead (Pb) on corticosterone after chronic and acute stress, brain monoamines, and blood Pb levels in rats. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 29: 45-55. PMID 20920575 DOI: 10.1016/j.ijdevneu.2010.09.008  0.96
2011 Braun AA, Skelton MR, Vorhees CV, Williams MT. Comparison of the elevated plus and elevated zero mazes in treated and untreated male Sprague-Dawley rats: effects of anxiolytic and anxiogenic agents. Pharmacology, Biochemistry, and Behavior. 97: 406-15. PMID 20869983 DOI: 10.1016/j.pbb.2010.09.013  0.96
2011 Vorhees CV, He E, Skelton MR, Graham DL, Schaefer TL, Grace CE, Braun AA, Amos-Kroohs R, Williams MT. Comparison of (+)-methamphetamine, ±-methylenedioxymethamphetamine, (+)-amphetamine and ±-fenfluramine in rats on egocentric learning in the Cincinnati water maze. Synapse (New York, N.Y.). 65: 368-78. PMID 20730798 DOI: 10.1002/syn.20854  0.96
2010 Grace CE, Schaefer TL, Graham DL, Skelton MR, Williams MT, Vorhees CV. Effects of inhibiting neonatal methamphetamine-induced corticosterone release in rats by adrenal autotransplantation on later learning, memory, and plasma corticosterone levels. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 28: 331-42. PMID 20184951 DOI: 10.1016/j.ijdevneu.2010.02.005  0.96
2010 Grace CE, Schaefer TL, Herring NR, Graham DL, Skelton MR, Gudelsky GA, Williams MT, Vorhees CV. Effect of a neurotoxic dose regimen of (+)-methamphetamine on behavior, plasma corticosterone, and brain monoamines in adult C57BL/6 mice. Neurotoxicology and Teratology. 32: 346-55. PMID 20096350 DOI: 10.1016/j.ntt.2010.01.006  0.96
2010 Sun Y, Liou B, Ran H, Skelton MR, Williams MT, Vorhees CV, Kitatani K, Hannun YA, Witte DP, Xu YH, Grabowski GA. Neuronopathic Gaucher disease in the mouse: viable combined selective saposin C deficiency and mutant glucocerebrosidase (V394L) mice with glucosylsphingosine and glucosylceramide accumulation and progressive neurological deficits. Human Molecular Genetics. 19: 1088-97. PMID 20047948 DOI: 10.1093/hmg/ddp580  0.96
2010 Sun Y, Ran H, Zamzow M, Kitatani K, Skelton MR, Williams MT, Vorhees CV, Witte DP, Hannun YA, Grabowski GA. Specific saposin C deficiency: CNS impairment and acid beta-glucosidase effects in the mouse. Human Molecular Genetics. 19: 634-47. PMID 20015957 DOI: 10.1093/hmg/ddp531  0.96
2009 Vorhees CV, Schaefer TL, Skelton MR, Grace CE, Herring NR, Williams MT. (+/-)3,4-Methylenedioxymethamphetamine (MDMA) dose-dependently impairs spatial learning in the morris water maze after exposure of rats to different five-day intervals from birth to postnatal day twenty. Developmental Neuroscience. 31: 107-20. PMID 19372692 DOI: 10.1159/000207499  0.96
2009 Skelton MR, Schaefer TL, Herring NR, Grace CE, Vorhees CV, Williams MT. Comparison of the developmental effects of 5-methoxy-N,N-diisopropyltryptamine (Foxy) to (+/-)-3,4-methylenedioxymethamphetamine (ecstasy) in rats. Psychopharmacology. 204: 287-97. PMID 19198809 DOI: 10.1007/s00213-009-1459-x  0.96
2009 Vorhees CV, Skelton MR, Grace CE, Schaefer TL, Graham DL, Braun AA, Williams MT. Effects of (+)-methamphetamine on path integration and spatial learning, but not locomotor activity or acoustic startle, align with the stress hyporesponsive period in rats. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 289-98. PMID 19136054 DOI: 10.1016/j.ijdevneu.2008.12.003  0.96
2008 Skelton MR, Able JA, Grace CE, Herring NR, Schaefer TL, Gudelsky GA, Vorhees CV, Williams MT. (+/-)-3,4-Methylenedioxymethamphetamine treatment in adult rats impairs path integration learning: a comparison of single vs once per week treatment for 5 weeks. Neuropharmacology. 55: 1121-30. PMID 18674550 DOI: 10.1016/j.neuropharm.2008.07.006  0.96
2008 Herring NR, Schaefer TL, Tang PH, Skelton MR, Lucot JP, Gudelsky GA, Vorhees CV, Williams MT. Comparison of time-dependent effects of (+)-methamphetamine or forced swim on monoamines, corticosterone, glucose, creatine, and creatinine in rats. Bmc Neuroscience. 9: 49. PMID 18513404 DOI: 10.1186/1471-2202-9-49  0.96
2008 Vorhees CV, Herring NR, Schaefer TL, Grace CE, Skelton MR, Johnson HL, Williams MT. Effects of neonatal (+)-methamphetamine on path integration and spatial learning in rats: effects of dose and rearing conditions. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 26: 599-610. PMID 18502078 DOI: 10.1016/j.ijdevneu.2008.04.002  0.96
2008 Sun Y, Witte DP, Ran H, Zamzow M, Barnes S, Cheng H, Han X, Williams MT, Skelton MR, Vorhees CV, Grabowski GA. Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice. Human Molecular Genetics. 17: 2345-56. PMID 18480170 DOI: 10.1093/hmg/ddn135  0.96
2008 Skelton MR, Williams MT, Vorhees CV. Developmental effects of 3,4-methylenedioxymethamphetamine: a review. Behavioural Pharmacology. 19: 91-111. PMID 18332674 DOI: 10.1097/FBP.0b013e3282f62c76  0.96
2008 Schaefer TL, Skelton MR, Herring NR, Gudelsky GA, Vorhees CV, Williams MT. Short- and long-term effects of (+)-methamphetamine and (+/-)-3,4-methylenedioxymethamphetamine on monoamine and corticosterone levels in the neonatal rat following multiple days of treatment. Journal of Neurochemistry. 104: 1674-85. PMID 17996031 DOI: 10.1111/j.1471-4159.2007.05112.x  0.96
2008 Grace CE, Schaefer TL, Herring NR, Skelton MR, McCrea AE, Vorhees CV, Williams MT. (+)-Methamphetamine increases corticosterone in plasma and BDNF in brain more than forced swim or isolation in neonatal rats. Synapse (New York, N.Y.). 62: 110-21. PMID 17992688 DOI: 10.1002/syn.20470  0.96
2007 Vorhees CV, Skelton MR, Williams MT. Age-dependent effects of neonatal methamphetamine exposure on spatial learning. Behavioural Pharmacology. 18: 549-62. PMID 17762523 DOI: 10.1097/FBP.0b013e3282ee2abe  0.96
2007 Skelton MR, Williams MT, Schaefer TL, Vorhees CV. Neonatal (+)-methamphetamine increases brain derived neurotrophic factor, but not nerve growth factor, during treatment and results in long-term spatial learning deficits. Psychoneuroendocrinology. 32: 734-45. PMID 17606327 DOI: 10.1016/j.psyneuen.2007.05.004  0.96
2007 Williams MT, Herring NR, Schaefer TL, Skelton MR, Campbell NG, Lipton JW, McCrea AE, Vorhees CV. Alterations in body temperature, corticosterone, and behavior following the administration of 5-methoxy-diisopropyltryptamine ('foxy') to adult rats: a new drug of abuse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1404-20. PMID 17047665 DOI: 10.1038/sj.npp.1301232  0.96
2006 Skelton MR, Williams MT, Vorhees CV. Treatment with MDMA from P11-20 disrupts spatial learning and path integration learning in adolescent rats but only spatial learning in older rats. Psychopharmacology. 189: 307-18. PMID 17016706 DOI: 10.1007/s00213-006-0563-4  0.96
2005 Cohen MA, Skelton MR, Schaefer TL, Gudelsky GA, Vorhees CV, Williams MT. Learning and memory after neonatal exposure to 3,4-methylenedioxymethamphetamine (ecstasy) in rats: interaction with exposure in adulthood. Synapse (New York, N.Y.). 57: 148-59. PMID 15945064 DOI: 10.1002/syn.20166  0.96
2005 Vorhees CV, Reed TM, Morford LL, Fukumura M, Wood SL, Brown CA, Skelton MR, McCrea AE, Rock SL, Williams MT. Periadolescent rats (P41-50) exhibit increased susceptibility to D-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21-30 or P31-40) or adult rats (P51-60). Neurotoxicology and Teratology. 27: 117-34. PMID 15681126 DOI: 10.1016/j.ntt.2004.09.005  0.96
2004 Skelton MR, Blankenmeyer TL, Gudelsky GA, Brown-Strittholt CA, Vorhees CV, Williams MT. Metyrapone attenuates the sequential learning deficits but not monoamine depletions following d,l-fenfluramine administration to adult rats. Synapse (New York, N.Y.). 54: 214-22. PMID 15484208 DOI: 10.1002/syn.20077  0.96
2004 Williams MT, Brown CA, Skelton MR, Vinks AA, Vorhees CV. Absorption and clearance of +/-3,4-methylenedioxymethamphetamine from the plasma of neonatal rats. Neurotoxicology and Teratology. 26: 849-56. PMID 15451048 DOI: 10.1016/j.ntt.2004.08.002  0.96
2004 Vorhees CV, Reed TM, Skelton MR, Williams MT. Exposure to 3,4-methylenedioxymethamphetamine (MDMA) on postnatal days 11-20 induces reference but not working memory deficits in the Morris water maze in rats: implications of prior learning. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 22: 247-59. PMID 15380825 DOI: 10.1016/j.ijdevneu.2004.06.003  0.96
2003 Skelton MR, Ponniah S, Wang DZ, Doetschman T, Vorhees CV, Pallen CJ. Protein tyrosine phosphatase alpha (PTP alpha) knockout mice show deficits in Morris water maze learning, decreased locomotor activity, and decreases in anxiety. Brain Research. 984: 1-10. PMID 12932834 DOI: 10.1016/S0006-8993(03)02839-7  0.96
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