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Michael E. Hildebrand, Ph.D. - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
ion channels, pain
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Sanner K, Kawell S, Evans JG, Elekovic V, Walz M, Joksimovic SL, Joksimovic SM, Donald RR, Tomic M, Orestes P, Feseha S, Dedek A, Ghodsi SM, Fallon IP, Lee J, ... ... Hildebrand ME, et al. Facilitation of Ca 3.2 channel gating in pain pathways reveals a novel mechanism of serum-induced hyperalgesia. Biorxiv : the Preprint Server For Biology. PMID 39868306 DOI: 10.1101/2025.01.03.631165  0.736
2024 Antunes FTT, Gandini MA, Gadotti VM, Quintão NLM, Santin JR, Souza IA, David LS, Snutch TP, Hildebrand M, Zamponi GW. Contribution of T-type calcium channel isoforms to cold and mechanical sensitivity in naïve and oxaliplatin-treated mice of both sexes. British Journal of Pharmacology. PMID 39295452 DOI: 10.1111/bph.17337  0.744
2023 Yadav A, Matson KJE, Li L, Hua I, Petrescu J, Kang K, Alkaslasi MR, Lee DI, Hasan S, Galuta A, Dedek A, Ameri S, Parnell J, Alshardan MM, Qumqumji FA, ... ... Hildebrand ME, et al. A cellular taxonomy of the adult human spinal cord. Neuron. 111: 328-344.e7. PMID 36731429 DOI: 10.1016/j.neuron.2023.01.007  0.558
2023 Correa BHM, Moreira CR, Hildebrand ME, Vieira LB. The Role of Voltage-Gated Calcium Channels in Basal Ganglia Neurodegenerative Disorders. Current Neuropharmacology. 21: 183-201. PMID 35339179 DOI: 10.2174/1570159X20666220327211156  0.304
2021 McNeill J, Rudyk C, Hildebrand ME, Salmaso N. Ion Channels and Electrophysiological Properties of Astrocytes: Implications for Emergent Stimulation Technologies. Frontiers in Cellular Neuroscience. 15: 644126. PMID 34093129 DOI: 10.3389/fncel.2021.644126  0.387
2021 Harding EK, Dedek A, Bonin RP, Salter MW, Snutch TP, Hildebrand ME. The T-type calcium channel antagonist, Z944, reduces spinal excitability and pain hypersensitivity. British Journal of Pharmacology. PMID 33871884 DOI: 10.1111/bph.15498  0.777
2020 Mahmoud H, Martin N, Hildebrand ME. Conserved contributions of NMDA receptor subtypes to synaptic responses in lamina II spinal neurons across early postnatal development. Molecular Brain. 13: 31. PMID 32138769 DOI: 10.1186/S13041-020-00566-9  0.354
2019 Dedek A, Xu J, Kandegedara CM, Lorenzo LÉ, Godin AG, De Koninck Y, Lombroso PJ, Tsai EC, Hildebrand ME. Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing. Brain : a Journal of Neurology. 142: 1535-1546. PMID 31135041 DOI: 10.1093/Brain/Awz105  0.4
2016 Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing. Cell Reports. 17: 2753-2765. PMID 27926876 DOI: 10.1016/J.Celrep.2016.11.024  0.75
2015 Hildebrand ME, Snutch TP. The unusual suspects: Regulation of retinal calcium channels by somatostatin. Channels (Austin, Tex.). 9: 61-2. PMID 25715059 DOI: 10.1080/19336950.2015.1018000  0.685
2014 Hildebrand ME, Pitcher GM, Harding EK, Li H, Beggs S, Salter MW. GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cord. Scientific Reports. 4: 4094. PMID 24522697 DOI: 10.1038/Srep04094  0.746
2014 Bourinet E, Altier C, Hildebrand ME, Trang T, Salter MW, Zamponi GW. Calcium-permeable ion channels in pain signaling. Physiological Reviews. 94: 81-140. PMID 24382884 DOI: 10.1152/Physrev.00023.2013  0.784
2012 Isope P, Hildebrand ME, Snutch TP. Contributions of T-type voltage-gated calcium channels to postsynaptic calcium signaling within Purkinje neurons. Cerebellum (London, England). 11: 651-65. PMID 20734177 DOI: 10.1007/S12311-010-0195-4  0.817
2011 Hildebrand ME, Mezeyova J, Smith PL, Salter MW, Tringham E, Snutch TP. Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons. Molecular Pain. 7: 67. PMID 21910862 DOI: 10.1186/1744-8069-7-67  0.793
2011 Hildebrand ME, Smith PL, Bladen C, Eduljee C, Xie JY, Chen L, Fee-Maki M, Doering CJ, Mezeyova J, Zhu Y, Belardetti F, Pajouhesh H, Parker D, Arneric SP, Parmar M, et al. A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain. Pain. 152: 833-43. PMID 21349638 DOI: 10.1016/J.Pain.2010.12.035  0.792
2010 Singh A, Hildebrand ME, Garcia E, Snutch TP. The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels. British Journal of Pharmacology. 160: 1464-75. PMID 20590636 DOI: 10.1111/J.1476-5381.2010.00786.X  0.735
2009 Hildebrand ME, Isope P, Miyazaki T, Nakaya T, Garcia E, Feltz A, Schneider T, Hescheler J, Kano M, Sakimura K, Watanabe M, Dieudonné S, Snutch TP. Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9668-82. PMID 19657020 DOI: 10.1523/Jneurosci.0362-09.2009  0.798
2008 Tao J, Hildebrand ME, Liao P, Liang MC, Tan G, Li S, Snutch TP, Soong TW. Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels. Molecular Pharmacology. 73: 1596-609. PMID 18292205 DOI: 10.1124/Mol.107.043612  0.767
2007 Hildebrand ME, David LS, Hamid J, Mulatz K, Garcia E, Zamponi GW, Snutch TP. Selective inhibition of Cav3.3 T-type calcium channels by Galphaq/11-coupled muscarinic acetylcholine receptors. The Journal of Biological Chemistry. 282: 21043-55. PMID 17535809 DOI: 10.1074/Jbc.M611809200  0.753
2006 Hildebrand ME, Snutch TP. Contributions of T-type calcium channels to the pathophysiology of pain signaling Drug Discovery Today: Disease Mechanisms. 3: 335-341. DOI: 10.1016/J.Ddmec.2006.10.001  0.753
2005 Vieira LB, Kushmerick C, Hildebrand ME, Garcia E, Stea A, Cordeiro MN, Richardson M, Gomez MV, Snutch TP. Inhibition of high voltage-activated calcium channels by spider toxin PnTx3-6. The Journal of Pharmacology and Experimental Therapeutics. 314: 1370-7. PMID 15933156 DOI: 10.1124/Jpet.105.087023  0.786
2004 Spacey SD, Hildebrand ME, Materek LA, Bird TD, Snutch TP. Functional implications of a novel EA2 mutation in the P/Q-type calcium channel. Annals of Neurology. 56: 213-20. PMID 15293273 DOI: 10.1002/Ana.20169  0.665
2004 McRory JE, Hamid J, Doering CJ, Garcia E, Parker R, Hamming K, Chen L, Hildebrand M, Beedle AM, Feldcamp L, Zamponi GW, Snutch TP. The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1707-18. PMID 14973233 DOI: 10.1523/Jneurosci.4846-03.2004  0.78
2004 Hildebrand ME, McRory JE, Snutch TP, Stea A. Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin. The Journal of Pharmacology and Experimental Therapeutics. 308: 805-13. PMID 14634047 DOI: 10.1124/Jpet.103.058792  0.82
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