Year |
Citation |
Score |
2024 |
Souza IA, Gandini MA, Ali MY, Kricek F, Skouteris G, Zamponi GW. Determinants of interactions of a novel next-generation gabapentinoid NVA1309 and mirogabalin with the Cavα2δ-1 subunit. Molecular Brain. 17: 54. PMID 39113108 DOI: 10.1186/s13041-024-01129-y |
0.511 |
|
2024 |
Ferron L, Harding EK, Gandini MA, Brideau C, Stys PK, Zamponi GW. Functional remodeling of presynaptic voltage-gated calcium channels in superficial layers of the dorsal horn during neuropathic pain. Iscience. 27: 109973. PMID 38827405 DOI: 10.1016/j.isci.2024.109973 |
0.629 |
|
2024 |
Kricek F, Ruf C, Meghani P, Souza IA, Gandini MA, Zamponi GW, Skouteris G. A next generation peripherally restricted Cavα2δ-1 ligand with inhibitory action on Cav2.2 channels and utility in neuropathic pain. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 174: 116472. PMID 38531121 DOI: 10.1016/j.biopha.2024.116472 |
0.53 |
|
2024 |
Gandini MA, Zamponi GW. Opening the K3.1 gates: A therapeutic strategy for progressive myoclonus epilepsy type 7? Cell Reports. Medicine. 5: 101425. PMID 38382469 DOI: 10.1016/j.xcrm.2024.101425 |
0.487 |
|
2023 |
Ferron L, Gandini MA, Zamponi GW. Fighting pain: the structure of gabapentin and its binding site in the Caαδ subunit. Nature Structural & Molecular Biology. 30: 717-719. PMID 37286823 DOI: 10.1038/s41594-023-01013-8 |
0.405 |
|
2023 |
Harding EK, Souza IA, Gandini MA, Gadotti VM, Ali MY, Huang S, Antunes FTT, Trang T, Zamponi GW. Differential regulation of Cav3.2 and Cav2.2 calcium channels by CB1 receptors and cannabidiol. British Journal of Pharmacology. PMID 36647671 DOI: 10.1111/bph.16035 |
0.648 |
|
2022 |
Gambeta E, Gandini MA, Souza IA, Zamponi GW. CaV3.2 calcium channels contribute to trigeminal neuralgia. Pain. PMID 35467587 DOI: 10.1097/j.pain.0000000000002651 |
0.788 |
|
2021 |
Gandini MA, Souza IA, Khullar A, Gambeta E, Zamponi GW. Correction to: Regulation of Ca3.2 channels by the receptor for activated C kinase 1 (Rack-1). Pflugers Archiv : European Journal of Physiology. PMID 34674025 DOI: 10.1007/s00424-021-02633-z |
0.77 |
|
2021 |
Gandini MA, Souza IA, Khullar A, Gambeta E, Zamponi GW. Regulation of Ca3.2 channels by the receptor for activated C kinase 1 (Rack-1). Pflugers Archiv : European Journal of Physiology. PMID 34623515 DOI: 10.1007/s00424-021-02631-1 |
0.796 |
|
2021 |
Souza IA, Gandini MA, Zamponi GW. Splice-variant specific effects of a CACNA1H mutation associated with writer's cramp. Molecular Brain. 14: 145. PMID 34544471 DOI: 10.1186/s13041-021-00861-z |
0.653 |
|
2021 |
Gandini MA, Zamponi GW. Voltage-gated calcium channel nanodomains: molecular composition and function. The Febs Journal. PMID 33576127 DOI: 10.1111/febs.15759 |
0.67 |
|
2021 |
Gandini MA, Souza IA, Ferron L, Innes AM, Zamponi GW. The de novo CACNA1A pathogenic variant Y1384C associated with hemiplegic migraine, early onset cerebellar atrophy and developmental delay leads to a loss of Cav2.1 channel function. Molecular Brain. 14: 27. PMID 33557884 DOI: 10.1186/s13041-021-00745-2 |
0.604 |
|
2021 |
Huang M, Nibbeling EAR, Lagrand TJ, Souza IA, Groen JL, Gandini MA, Zhang FX, Koelman JHTM, Adir N, Sinke RJ, Zamponi GW, Tijssen MAJ, Verbeek DS. Rare functional missense variants in CACNA1H: What can we learn from Writer's cramp? Molecular Brain. 14: 18. PMID 33478561 DOI: 10.1186/s13041-021-00736-3 |
0.549 |
|
2021 |
Gambeta E, Gandini MA, Souza IA, Ferron L, Zamponi GW. A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav2.1 channels. Molecular Brain. 14: 4. PMID 33413531 DOI: 10.1186/s13041-020-00725-y |
0.805 |
|
2020 |
Ficelova V, Souza IA, Cmarko L, Gandini MA, Stringer RN, Zamponi GW, Weiss N. Functional identification of potential non-canonical N-glycosylation sites within Ca3.2 T-type calcium channels. Molecular Brain. 13: 149. PMID 33176830 DOI: 10.1186/s13041-020-00697-z |
0.652 |
|
2020 |
Huang J, Gandini MA, Chen L, M'Dahoma S, Stemkowski PL, Chung H, Muruve DA, Zamponi GW. Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk. Cell Reports. 33: 108233. PMID 33027646 DOI: 10.1016/j.celrep.2020.108233 |
0.4 |
|
2020 |
Nam Y, Ryu KD, Jang C, Moon YH, Kim M, Ko D, Chung KS, Gandini MA, Lee KT, Zamponi GW, Lee JY. Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers. Bioorganic & Medicinal Chemistry. 115491. PMID 32327350 DOI: 10.1016/J.Bmc.2020.115491 |
0.622 |
|
2020 |
Huang J, Gandini MA, M’dahoma S, Muruve DA, Zamponi GW. Regulation of pain signaling by the innate immune system Proceedings For Annual Meeting of the Japanese Pharmacological Society. 93: 2-S24-1. DOI: 10.1254/jpssuppl.93.0_2-s24-1 |
0.391 |
|
2019 |
Gandini MA, Souza IA, Raval D, Xu J, Pan YX, Zamponi GW. Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors. Molecular Brain. 12: 98. PMID 31775826 DOI: 10.1186/S13041-019-0524-6 |
0.642 |
|
2019 |
Souza IA, Gandini MA, Zhang FX, Mitchell WG, Matsumoto J, Lerner J, Pierson TM, Zamponi GW. Pathogenic Cav3.2 channel mutation in a child with primary generalized epilepsy. Molecular Brain. 12: 86. PMID 31651342 DOI: 10.1186/S13041-019-0509-5 |
0.597 |
|
2019 |
Aygün Cevher H, Schaller D, Gandini MA, Kaplan O, Gambeta E, Zhang FX, Çelebier M, Tahir MN, Zamponi GW, Wolber G, Gündüz MG. Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels. Bioorganic Chemistry. 91: 103187. PMID 31419643 DOI: 10.1016/J.Bioorg.2019.103187 |
0.772 |
|
2019 |
Gandini MA, Souza IA, Fan J, Li K, Wang D, Zamponi GW. Interactions of Rabconnectin-3 with Cav2 calcium channels. Molecular Brain. 12: 62. PMID 31253182 DOI: 10.1186/S13041-019-0483-Y |
0.667 |
|
2019 |
Helbig KL, Lauerer RJ, Bahr JC, Souza IA, Myers CT, Uysal B, Schwarz N, Gandini MA, Huang S, Keren B, Mignot C, Afenjar A, Billette de Villemeur T, Héron D, Nava C, et al. De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias. American Journal of Human Genetics. 104: 562. PMID 30849329 DOI: 10.1016/j.ajhg.2019.02.015 |
0.381 |
|
2019 |
Garcia-Caballero A, Gandini MA, Huang S, Chen L, Souza IA, Dang YL, Stutts MJ, Zamponi GW. Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC. Molecular Brain. 12: 12. PMID 30736831 DOI: 10.1186/S13041-019-0433-8 |
0.712 |
|
2018 |
Helbig KL, Lauerer RJ, Bahr JC, Souza IA, Myers CT, Uysal B, Schwarz N, Gandini MA, Huang S, Keren B, Mignot C, Afenjar A, Billette de Villemeur T, Héron D, Nava C, et al. De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias. American Journal of Human Genetics. PMID 30343943 DOI: 10.1016/j.ajhg.2018.09.006 |
0.59 |
|
2018 |
Bellampalli SS, Ji Y, Moutal A, Cai S, Wijeratne EMK, Gandini MA, Yu J, Chefdeville A, Dorame A, Chew LA, Madura CL, Luo S, Molnar G, Khanna M, Streicher JM, et al. Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels. Pain. PMID 30169422 DOI: 10.1097/J.Pain.0000000000001385 |
0.615 |
|
2017 |
Sandoval A, Duran P, Gandini MA, Andrade A, Almanza A, Kaja S, Felix R. Regulation of L-type CaV1.3 channel activity and insulin secretion by the cGMP-PKG signaling pathway. Cell Calcium. 66: 1-9. PMID 28807144 DOI: 10.1016/J.Ceca.2017.05.008 |
0.583 |
|
2017 |
Fan J, Gandini MA, Zhang FX, Chen L, Souza IA, Zamponi GW. Down-regulation of T-type Cav3.2 channels by hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1): evidence of a signaling complex. Channels (Austin, Tex.). 0. PMID 28467171 DOI: 10.1080/19336950.2017.1326233 |
0.705 |
|
2016 |
Fan J, Stemkowski PL, Gandini MA, Black SA, Zhang Z, Souza IA, Chen L, Zamponi GW. Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice. Frontiers in Cellular Neuroscience. 10: 74. PMID 27047338 DOI: 10.3389/Fncel.2016.00074 |
0.595 |
|
2015 |
Souza IA, Gandini MA, Wan MM, Zamponi GW. Two heterozygous Cav3.2 channel mutations in a pediatric chronic pain patient: recording condition-dependent biophysical effects. Pflugers Archiv : European Journal of Physiology. PMID 26706850 DOI: 10.1007/S00424-015-1776-3 |
0.707 |
|
2015 |
Grabner CP, Gandini MA, Rehak R, Le Y, Zamponi GW, Schmitz F. RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13133-47. PMID 26400943 DOI: 10.1523/Jneurosci.0658-15.2015 |
0.679 |
|
2015 |
López Soto EJ, Agosti F, Cabral A, Mustafa ER, Damonte VM, Gandini MA, Rodríguez S, Castrogiovanni D, Felix R, Perelló M, Raingo J. Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons. The Journal of General Physiology. 146: 205-19. PMID 26283199 DOI: 10.1085/Jgp.201511383 |
0.464 |
|
2015 |
Gandini MA, Felix R. Molecular and functional interplay of voltage-gated Ca(2+) channels with the cytoskeleton. Current Molecular Pharmacology. 8: 69-80. PMID 25966702 DOI: 10.2174/1874467208666150507094252 |
0.599 |
|
2015 |
Gandini MA, Sandoval A, Felix R. Toxins targeting voltage-activated Ca2+ channels and their potential biomedical applications. Current Topics in Medicinal Chemistry. 15: 604-16. PMID 25714378 DOI: 10.2174/1568026615666150225112605 |
0.571 |
|
2015 |
Grabner CP, Gandini MA, Rehak R, Le Y, Zamponi GW, Schmitz F. RIM1/2-mediated facilitation of cav1.4 channel opening is required for Ca2+-stimulated release in mouse rod photoreceptors Journal of Neuroscience. 35: 13133-13147. DOI: 10.1523/JNEUROSCI.0627-15.2015 |
0.613 |
|
2015 |
Gandini MA, Sandoval A, Felix R. Toxins targeting voltage-activated Ca2+ channels and their potential biomedical applications Current Topics in Medicinal Chemistry. 15: 604-616. |
0.47 |
|
2015 |
Gandini MA, Felix R. Molecular and Functional Interplay of Voltage-Gated Ca2+ Channels with the Cytoskeleton Current Molecular Pharmacology. 8: 69-80. |
0.496 |
|
2014 |
Gandini MA, Sandoval A, Zamponi GW, Felix R. The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels. Channels (Austin, Tex.). 8: 452-7. PMID 25483588 DOI: 10.4161/19336950.2014.949162 |
0.692 |
|
2014 |
Canto-Bustos M, Loeza-Alcocer E, González-Ramírez R, Gandini MA, Delgado-Lezama R, Felix R. Functional expression of T-type Ca2+ channels in spinal motoneurons of the adult turtle. Plos One. 9: e108187. PMID 25255145 DOI: 10.1371/Journal.Pone.0108187 |
0.566 |
|
2014 |
Gandini MA, Sandoval A, Felix R. Whole-cell patch-clamp recording of recombinant voltage-sensitive Ca2+ channels heterologously expressed in HEK-293 cells. Cold Spring Harbor Protocols. 2014: 396-401. PMID 24692488 DOI: 10.1101/Pdb.Prot073213 |
0.594 |
|
2014 |
Gandini MA, Sandoval A, Felix R. Whole-cell patch-clamp recordings of Ca2+ currents from isolated neonatal mouse dorsal root ganglion (DRG) neurons. Cold Spring Harbor Protocols. 2014: 389-95. PMID 24692487 DOI: 10.1101/Pdb.Prot073205 |
0.433 |
|
2014 |
Gandini MA, Sandoval A, Felix R. Patch-clamp recording of voltage-sensitive Ca2+ channels. Cold Spring Harbor Protocols. 2014: 329-5. PMID 24692484 DOI: 10.1101/Pdb.Top066092 |
0.514 |
|
2014 |
Gandini MA, Henríquez DR, Grimaldo L, Sandoval A, Altier C, Zamponi GW, Felix R, González-Billault C. CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation. PflüGers Archiv : European Journal of Physiology. 466: 2113-26. PMID 24566975 DOI: 10.1007/S00424-014-1476-4 |
0.674 |
|
2013 |
Garza-López E, González-RamÃrez R, Gandini MA, Sandoval A, Felix R. The familial hemiplegic migraine type 1 mutation K1336E affects direct G protein-mediated regulation of neuronal P/Q-type Ca2+ channels. Cephalalgia : An International Journal of Headache. 33: 398-407. PMID 23430985 DOI: 10.1177/0333102412475236 |
0.515 |
|
2012 |
Gandini MA. Channeling headache: novel findings in the study of Ca(2+)-channels and FHM-1. Channels (Austin, Tex.). 6: 414-5. PMID 22991044 DOI: 10.4161/Chan.22146 |
0.455 |
|
2012 |
Garza-López E, Sandoval A, González-RamÃrez R, Gandini MA, Van den Maagdenberg A, De Waard M, Felix R. Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels. Biochimica Et Biophysica Acta. 1822: 1238-46. PMID 22549042 DOI: 10.1016/J.Bbadis.2012.04.008 |
0.568 |
|
2012 |
Gandini MA, Felix R. Functional interactions between voltage-gated Ca(2+) channels and Rab3-interacting molecules (RIMs): new insights into stimulus-secretion coupling. Biochimica Et Biophysica Acta. 1818: 551-8. PMID 22198390 DOI: 10.1016/J.Bbamem.2011.12.011 |
0.562 |
|
2011 |
Gandini MA, Sandoval A, González-RamÃrez R, Mori Y, de Waard M, Felix R. Functional coupling of Rab3-interacting molecule 1 (RIM1) and L-type Ca2+ channels in insulin release. The Journal of Biological Chemistry. 286: 15757-65. PMID 21402706 DOI: 10.1074/Jbc.M110.187757 |
0.537 |
|
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