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Miguel Garcia-Diaz - Publications

Affiliations: 
Biochemistry and Structural Biology Stony Brook University, Stony Brook, NY, United States 
Area:
Biochemistry
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61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Choi WS, Garcia-Diaz M. A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM). Nucleic Acids Research. PMID 34928349 DOI: 10.1093/nar/gkab1230  0.409
2021 Pellicanò G, Al Mamun M, Jurado-Santiago D, Villa-Hernández S, Yin X, Giannattasio M, Lanz MC, Smolka MB, Yeeles J, Shirahige K, García-Díaz M, Bermejo R. Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse. Molecular Cell. PMID 33932350 DOI: 10.1016/j.molcel.2021.04.006  0.375
2020 Bonds A, Yuan T, Werman J, Jang J, Lu R, Nesbitt NM, Garcia-Diaz M, Sampson NS. Post-translational succinylation of enoyl-CoA hydratase EchA19 slows catalytic hydration of cholesterol catabolite 3-oxo-chol-4,22-diene-24-oyl-CoA. Acs Infectious Diseases. PMID 32649175 DOI: 10.1021/Acsinfecdis.0C00329  0.322
2020 Butler TJ, Estep KN, Sommers JA, Maul RW, Moore AZ, Bandinelli S, Cucca F, Tuke MA, Wood AR, Bharti SK, Bogenhagen DF, Yakubovskaya E, Garcia-Diaz M, Guilliam TA, Byrd AK, et al. Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro. Human Molecular Genetics. PMID 32191790 DOI: 10.1093/Hmg/Ddaa043  0.463
2019 Shanbhogue P, Hoffmann RM, Airola MV, Maini R, Hamelin DJ, Garcia-Diaz M, Burke JE, Hannun YA. The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme. The Journal of Biological Chemistry. PMID 30890560 DOI: 10.1074/Jbc.Ra118.007288  0.317
2018 Guha M, Srinivasan S, Johnson FB, Ruthel G, Guja K, Garcia-Diaz M, Kaufman BA, Glineburg MR, Fang J, Nakagawa H, Basha J, Kundu T, Avadhani NG. hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction. Plos One. 13: e0206897. PMID 30427907 DOI: 10.1371/Journal.Pone.0206897  0.344
2018 Bogenhagen DF, Ostermeyer-Fay AG, Haley JD, Garcia-Diaz M. Kinetics and Mechanism of Mammalian Mitochondrial Ribosome Assembly. Cell Reports. 22: 1935-1944. PMID 29444443 DOI: 10.1016/J.Celrep.2018.01.066  0.367
2017 Airola MV, Shanbhogue P, Shamseddine AA, Guja KE, Senkal CE, Maini R, Bartke N, Wu BX, Obeid LM, Garcia-Diaz M, Hannun YA. Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28652336 DOI: 10.1073/Pnas.1705134114  0.362
2017 Hauser K, He Y, Garcia-Diaz M, Simmerling C, Coutsias EA. Characterization of Biomolecular Helices and Their Complementarity Using Geometric Analysis. Journal of Chemical Information and Modeling. PMID 28287728 DOI: 10.1021/Acs.Jcim.6B00721  0.334
2016 Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Szanto AK, Nakagawa H, Basha J, Kundu T, et al. HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression. Cell Discovery. 2: 16045. PMID 27990297 DOI: 10.1038/Celldisc.2016.45  0.381
2016 Burak MJ, Guja KE, Hambardjieva E, Derkunt B, Garcia-Diaz M. A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG. The Embo Journal. PMID 27481934 DOI: 10.15252/embj.201694332  0.376
2016 Khan I, Crouch JD, Bharti SK, Sommers JA, Carney SM, Yakubovskaya E, Garcia-Diaz M, Trakselis MA, Brosh RM. Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: Substrate Specificity, DNA Branch-Migration, and Ability to Overcome Blockades to DNA Unwinding. The Journal of Biological Chemistry. PMID 27226550 DOI: 10.1074/Jbc.M115.712026  0.547
2015 Hauser K, Essuman B, He Y, Coutsias E, Garcia-Diaz M, Simmerling C. A human transcription factor in search mode. Nucleic Acids Research. PMID 26673724 DOI: 10.1093/Nar/Gkv1091  0.49
2015 Byrnes J, Hauser K, Norona L, Mejia E, Simmerling C, Garcia-Diaz M. Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion. Journal of Molecular Biology. PMID 26523681 DOI: 10.1016/J.Jmb.2015.10.021  0.493
2015 Burak MJ, Guja KE, Garcia-Diaz M. Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda. Nucleic Acids Research. 43: 8089-99. PMID 26220180 DOI: 10.1093/Nar/Gkv760  0.524
2015 Yang M, Lu R, Guja KE, Wipperman MF, St Clair JR, Bonds AC, Garcia-Diaz M, Sampson NS. Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA. Acs Infectious Diseases. 1: 110-125. PMID 26161441 DOI: 10.1021/Id500033M  0.329
2015 Lai CT, Li HJ, Yu W, Shah S, Bommineni GR, Perrone V, Garcia-Diaz M, Tonge PJ, Simmerling C. Rational Modulation of the Induced-Fit Conformational Change for Slow-Onset Inhibition in Mycobacterium tuberculosis InhA. Biochemistry. 54: 4683-91. PMID 26147157 DOI: 10.1021/Acs.Biochem.5B00284  0.335
2014 Yang M, Guja KE, Thomas ST, Garcia-Diaz M, Sampson NS. A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis. Acs Chemical Biology. 9: 2632-45. PMID 25203216 DOI: 10.1021/Cb500232H  0.355
2014 Mejia E, Burak M, Alonso A, Larraga V, Kunkel TA, Bebenek K, Garcia-Diaz M. Structures of the Leishmania infantum polymerase beta. Dna Repair. 18: 1-9. PMID 24666693 DOI: 10.1016/J.Dnarep.2014.03.001  0.44
2014 Venkataraman K, Guja KE, Garcia-Diaz M, Karzai AW. Non-stop mRNA decay: a special attribute of trans-translation mediated ribosome rescue. Frontiers in Microbiology. 5: 93. PMID 24653719 DOI: 10.3389/Fmicb.2014.00093  0.31
2014 Li HJ, Lai CT, Pan P, Yu W, Liu N, Bommineni GR, Garcia-Diaz M, Simmerling C, Tonge PJ. A structural and energetic model for the slow-onset inhibition of the Mycobacterium tuberculosis enoyl-ACP reductase InhA. Acs Chemical Biology. 9: 986-93. PMID 24527857 DOI: 10.1021/Cb400896G  0.358
2014 Yakubovskaya E, Guja KE, Eng ET, Choi WS, Mejia E, Beglov D, Lukin M, Kozakov D, Garcia-Diaz M. Organization of the human mitochondrial transcription initiation complex. Nucleic Acids Research. 42: 4100-12. PMID 24413562 DOI: 10.1093/Nar/Gkt1360  0.424
2014 Garrido P, Mejia E, Garcia-Diaz M, Blanco L, Picher AJ. The active site of TthPolX is adapted to prevent 8-oxo-dGTP misincorporation. Nucleic Acids Research. 42: 534-43. PMID 24084083 DOI: 10.1093/Nar/Gkt870  0.423
2013 Jacewicz A, Trzemecka A, Guja KE, Plochocka D, Yakubovskaya E, Bebenek A, Garcia-Diaz M. A remote palm domain residue of RB69 DNA polymerase is critical for enzyme activity and influences the conformation of the active site. Plos One. 8: e76700. PMID 24116139 DOI: 10.1371/Journal.Pone.0076700  0.455
2013 Guja KE, Venkataraman K, Yakubovskaya E, Shi H, Mejia E, Hambardjieva E, Karzai AW, Garcia-Diaz M. Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1. Nucleic Acids Research. 41: 7947-59. PMID 23804760 DOI: 10.1093/Nar/Gkt547  0.393
2013 Yakubovskaya E, Mejia E, Byrnes J, Hambardjieva E, Garcia-Diaz M. 125 Put a stop to it: termination of mitochondrial transcription Journal of Biomolecular Structure & Dynamics. 31: 80-81. DOI: 10.1080/07391102.2013.786367  0.486
2012 Yakubovskaya E, Guja KE, Mejia E, Castano S, Hambardjieva E, Choi WS, Garcia-Diaz M. Structure of the essential MTERF4:NSUN4 protein complex reveals how an MTERF protein collaborates to facilitate rRNA modification. Structure (London, England : 1993). 20: 1940-7. PMID 23022348 DOI: 10.1016/J.Str.2012.08.027  0.389
2012 Bruni F, Manzari C, Filice M, Loguercio Polosa P, Colella M, Carmone C, Hambardjieva E, Garcia-Diaz M, Cantatore P, Roberti M. D-MTERF5 is a novel factor modulating transcription in Drosophila mitochondria Mitochondrion. 12: 492-499. PMID 22784680 DOI: 10.1016/J.Mito.2012.06.010  0.353
2012 Guja KE, Garcia-Diaz M. Hitting the brakes: termination of mitochondrial transcription. Biochimica Et Biophysica Acta. 1819: 939-47. PMID 22137970 DOI: 10.1016/J.Bbagrm.2011.11.004  0.343
2011 Li HJ, Li X, Liu N, Zhang H, Truglio JJ, Mishra S, Kisker C, Garcia-Diaz M, Tonge PJ. Mechanism of the intramolecular Claisen condensation reaction catalyzed by MenB, a crotonase superfamily member. Biochemistry. 50: 9532-44. PMID 21830810 DOI: 10.1021/Bi200877X  0.374
2011 Babiychuk E, Vandepoele K, Wissing J, Garcia-Diaz M, De Rycke R, Akbari H, Joubès J, Beeckman T, Jänsch L, Frentzen M, Van Montagu MC, Kushnir S. Plastid gene expression and plant development require a plastidic protein of the mitochondrial transcription termination factor family. Proceedings of the National Academy of Sciences of the United States of America. 108: 6674-9. PMID 21464319 DOI: 10.1073/Pnas.1103442108  0.376
2010 Yakubovskaya E, Mejia E, Byrnes J, Hambardjieva E, Garcia-Diaz M. Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription Cell. 141: 982-993. PMID 20550934 DOI: 10.1016/J.Cell.2010.05.018  0.457
2010 Bebenek K, Garcia-Diaz M, Zhou RZ, Povirk LF, Kunkel TA. Loop 1 modulates the fidelity of DNA polymerase lambda. Nucleic Acids Research. 38: 5419-31. PMID 20435673 DOI: 10.1093/Nar/Gkq261  0.537
2010 Garcia-Diaz M, Murray MS, Kunkel TA, Chou KM. Interaction between DNA Polymerase lambda and anticancer nucleoside analogs. The Journal of Biological Chemistry. 285: 16874-9. PMID 20348107 DOI: 10.1074/Jbc.M109.094391  0.535
2010 Scotto-Lavino E, Garcia-Diaz M, Du G, Frohman MA. Basis for the isoform-specific interaction of myosin phosphatase subunits protein phosphatase 1c beta and myosin phosphatase targeting subunit 1. The Journal of Biological Chemistry. 285: 6419-24. PMID 20042605 DOI: 10.1074/Jbc.M109.074773  0.325
2009 Terrados G, Capp JP, Canitrot Y, García-Díaz M, Bebenek K, Kirchhoff T, Villanueva A, Boudsocq F, Bergoglio V, Cazaux C, Kunkel TA, Hoffmann JS, Blanco L. Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Plos One. 4: e7290. PMID 19806195 DOI: 10.1371/Journal.Pone.0007290  0.398
2009 Garcia-Diaz M, Bebenek K, Larrea AA, Havener JM, Perera L, Krahn JM, Pedersen LC, Ramsden DA, Kunkel TA. Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Nature Structural & Molecular Biology. 16: 967-72. PMID 19701199 DOI: 10.1038/Nsmb.1654  0.515
2008 Cisneros GA, Perera L, García-Díaz M, Bebenek K, Kunkel TA, Pedersen LG. Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies. Dna Repair. 7: 1824-34. PMID 18692600 DOI: 10.1016/J.Dnarep.2008.07.007  0.467
2008 Zhou RZ, Blanco L, Garcia-Diaz M, Bebenek K, Kunkel TA, Povirk LF. Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts. Nucleic Acids Research. 36: 2895-905. PMID 18385158 DOI: 10.1093/Nar/Gkn126  0.488
2008 Bebenek K, Garcia-Diaz M, Foley MC, Pedersen LC, Schlick T, Kunkel TA. Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Embo Reports. 9: 459-64. PMID 18369368 DOI: 10.1038/Embor.2008.33  0.421
2007 Garcia-Diaz M, Bebenek K. Multiple functions of DNA polymerases. Critical Reviews in Plant Sciences. 26: 105-122. PMID 18496613 DOI: 10.1080/07352680701252817  0.483
2007 Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC. The X family portrait: structural insights into biological functions of X family polymerases. Dna Repair. 6: 1709-25. PMID 17631059 DOI: 10.1016/J.Dnarep.2007.05.009  0.48
2007 Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA. Role of the catalytic metal during polymerization by DNA polymerase lambda. Dna Repair. 6: 1333-40. PMID 17475573 DOI: 10.1016/J.Dnarep.2007.03.005  0.419
2007 Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Structural insight into the substrate specificity of DNA Polymerase mu. Nature Structural & Molecular Biology. 14: 45-53. PMID 17159995 DOI: 10.1038/Nsmb1180  0.531
2007 Arana ME, Takata K, Garcia-Diaz M, Wood RD, Kunkel TA. A unique error signature for human DNA polymerase nu. Dna Repair. 6: 213-23. PMID 17118716 DOI: 10.1016/J.Dnarep.2006.09.012  0.447
2007 Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Erratum: Corrigendum: Structural insight into the substrate specificity of DNA Polymerase μ Nature Structural & Molecular Biology. 14: 680-680. DOI: 10.1038/Nsmb0707-680B  0.503
2006 Picher AJ, García-Díaz M, Bebenek K, Pedersen LC, Kunkel TA, Blanco L. Promiscuous mismatch extension by human DNA polymerase lambda. Nucleic Acids Research. 34: 3259-66. PMID 16807316 DOI: 10.1093/Nar/Gkl377  0.52
2006 Garcia-Diaz M, Kunkel TA. Mechanism of a genetic glissando: structural biology of indel mutations. Trends in Biochemical Sciences. 31: 206-14. PMID 16545956 DOI: 10.1016/J.Tibs.2006.02.004  0.503
2006 Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA. Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Cell. 124: 331-42. PMID 16439207 DOI: 10.1016/J.Cell.2005.10.039  0.506
2005 Garcia-Diaz M, Bebenek K, Gao G, Pedersen LC, London RE, Kunkel TA. Structure-function studies of DNA polymerase lambda. Dna Repair. 4: 1358-67. PMID 16213194 DOI: 10.1016/J.Dnarep.2005.09.001  0.517
2005 Nick McElhinny SA, Havener JM, Garcia-Diaz M, Juárez R, Bebenek K, Kee BL, Blanco L, Kunkel TA, Ramsden DA. A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Molecular Cell. 19: 357-66. PMID 16061182 DOI: 10.1016/J.Molcel.2005.06.012  0.458
2005 Bebenek K, Garcia-Diaz M, Patishall SR, Kunkel TA. Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV. The Journal of Biological Chemistry. 280: 20051-8. PMID 15778218 DOI: 10.1074/Jbc.M501981200  0.504
2005 Garcia-Diaz M, Bebenek K, Krahn JM, Kunkel TA, Pedersen LC. A closed conformation for the Pol lambda catalytic cycle. Nature Structural & Molecular Biology. 12: 97-8. PMID 15608652 DOI: 10.1038/Nsmb876  0.502
2004 Garcia-Diaz M, Bebenek K, Krahn JM, Blanco L, Kunkel TA, Pedersen LC. A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Molecular Cell. 13: 561-72. PMID 14992725 DOI: 10.1016/S1097-2765(04)00061-9  0.547
2004 Lee JW, Blanco L, Zhou T, Garcia-Diaz M, Bebenek K, Kunkel TA, Wang Z, Povirk LF. Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. The Journal of Biological Chemistry. 279: 805-11. PMID 14561766 DOI: 10.1074/Jbc.M307913200  0.496
2003 DeRose EF, Kirby TW, Mueller GA, Bebenek K, Garcia-Diaz M, Blanco L, Kunkel TA, London RE. Solution structure of the lyase domain of human DNA polymerase lambda. Biochemistry. 42: 9564-74. PMID 12911298 DOI: 10.1021/Bi034298S  0.524
2003 Ruiz JF, Juárez R, García-Díaz M, Terrados G, Picher AJ, González-Barrera S, Fernández de Henestrosa AR, Blanco L. Lack of sugar discrimination by human Pol mu requires a single glycine residue. Nucleic Acids Research. 31: 4441-9. PMID 12888504  0.424
2003 Bebenek K, Garcia-Diaz M, Blanco L, Kunkel TA. The frameshift infidelity of human DNA polymerase lambda. Implications for function. The Journal of Biological Chemistry. 278: 34685-90. PMID 12829698 DOI: 10.1074/Jbc.M305705200  0.515
2003 García-Díaz M, Ruiz JF, Juárez R, Terrados G, Blanco L. Are there mutator polymerases? Thescientificworldjournal. 3: 422-31. PMID 12806103 DOI: 10.1100/Tsw.2003.32  0.473
2002 García-Díaz M, Bebenek K, Sabariegos R, Domínguez O, Rodríguez J, Kirchhoff T, García-Palomero E, Picher AJ, Juárez R, Ruiz JF, Kunkel TA, Blanco L. DNA polymerase lambda, a novel DNA repair enzyme in human cells. The Journal of Biological Chemistry. 277: 13184-91. PMID 11821417 DOI: 10.1074/jbc.M111601200  0.444
2001 Taladriz S, Hanke T, Ramiro MJ, García-Díaz M, Lacoba MGd, Blanco L, Larraga V. Nuclear DNA polymerase beta from Leishmania infantum. Cloning, molecular analysis and developmental regulation Nucleic Acids Research. 29: 3822-3834. PMID 11557814 DOI: 10.1093/Nar/29.18.3822  0.402
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