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Martin L Duennwald, PhD - Publications

Affiliations: 
BBRI 
Area:
protein folding, Huntington's disease, aging
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Qiu Y, Kenana R, Beharry A, Wilhelm SDP, Hsu SY, Siu VM, Duennwald M, Heinemann IU. Histidine supplementation can escalate or rescue HARS deficiency in a Charcot Marie Tooth Disease model. Human Molecular Genetics. PMID 36164730 DOI: 10.1093/hmg/ddac239  0.328
2022 Dilliott AA, Andary CM, Stoltz M, Petropavlovskiy AA, Farhan SMK, Duennwald ML. DnaJC7 in Amyotrophic Lateral Sclerosis. International Journal of Molecular Sciences. 23. PMID 35456894 DOI: 10.3390/ijms23084076  0.444
2022 Rutledge BS, Choy WY, Duennwald ML. Folding or holding?-Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease. The Journal of Biological Chemistry. 298: 101905. PMID 35398094 DOI: 10.1016/j.jbc.2022.101905  0.497
2022 Ngo V, Karunatilleke NC, Brickenden A, Choy WY, Duennwald ML. Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1. Antioxidants (Basel, Switzerland). 11. PMID 35204126 DOI: 10.3390/antiox11020243  0.312
2022 Ngo V, Brickenden A, Liu H, Yeung C, Choy WY, Duennwald ML. A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90. Disease Models & Mechanisms. PMID 35088844 DOI: 10.1242/dmm.049258  0.35
2021 Salem A, Wilson CJ, Rutledge BS, Dilliott A, Farhan S, Choy WY, Duennwald ML. Matrin3: Disorder and ALS Pathogenesis. Frontiers in Molecular Biosciences. 8: 794646. PMID 35083279 DOI: 10.3389/fmolb.2021.794646  0.321
2021 Lant JT, Kiri R, Duennwald ML, O'Donoghue P. Formation and persistence of polyglutamine aggregates in mistranslating cells. Nucleic Acids Research. 49: 11883-11899. PMID 34718744 DOI: 10.1093/nar/gkab898  0.449
2021 Morey TM, Esmaeili MA, Duennwald ML, Rylett RJ. SPAAC Pulse-Chase: A Novel Click Chemistry-Based Method to Determine the Half-Life of Cellular Proteins. Frontiers in Cell and Developmental Biology. 9: 722560. PMID 34557490 DOI: 10.3389/fcell.2021.722560  0.633
2021 Lin LT, Razzaq A, Di Gregorio SE, Hong S, Charles B, Lopes MH, Beraldo F, Prado VF, Prado MAM, Duennwald ML. Hsp90 and its co-chaperone Sti1 control TDP-43 misfolding and toxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21594. PMID 33908654 DOI: 10.1096/fj.202002645R  0.522
2020 Di Gregorio SE, Volkening K, Strong MJ, Duennwald ML. Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network. International Journal of Molecular Sciences. 21. PMID 32764283 DOI: 10.3390/Ijms21165597  0.451
2019 Lackie RE, Razzaq AR, Farhan SMK, Qiu LR, Moshitzky G, Beraldo FH, Lopes MH, Maciejewski A, Gros R, Fan J, Choy WY, Greenberg DS, Martins VR, Duennwald ML, Lerch JP, et al. Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1. Journal of Neurochemistry. PMID 31562773 DOI: 10.1111/Jnc.14882  0.392
2019 Chadwick SR, Fazio EN, Etedali-Zadeh P, Genereaux J, Duennwald ML, Lajoie P. A functional unfolded protein response is required for chronological aging in Saccharomyces cerevisiae. Current Genetics. PMID 31346745 DOI: 10.1007/S00294-019-01019-0  0.424
2019 Jiang Y, Berg MD, Genereaux J, Ahmed K, Duennwald ML, Brandl CJ, Lajoie P. Sfp1 links TORC1 and cell growth regulation to the yeast SAGA-complex component Tra1 in response to polyQ proteotoxicity. Traffic (Copenhagen, Denmark). PMID 30740854 DOI: 10.1111/Tra.12637  0.497
2019 Spratt DE, Barber KR, Marlatt NM, Ngo V, Macklin JA, Xiao Y, Konermann L, Duennwald ML, Shaw GS. A Subset of Calcium-binding S100 Proteins Show Preferential Heterodimerization. The Febs Journal. PMID 30719832 DOI: 10.1111/Febs.14775  0.512
2019 Chung CZ, Jaramillo JE, Ellis MJ, Bour DYN, Seidl LE, Jo DHS, Turk MA, Mann MR, Bi Y, Haniford DB, Duennwald ML, Heinemann IU. RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe. Nucleic Acids Research. PMID 30715470 DOI: 10.1093/Nar/Gkz043  0.323
2018 Jiang Y, Di Gregorio S, Albakri MB, Duennwald ML, Lajoie P. Effect of Fluorescent Proteins on Fusion Partners Using Polyglutamine Toxicity Assays in Yeast. Journal of Visualized Experiments : Jove. PMID 30582582 DOI: 10.3791/58748  0.461
2018 Di Gregorio SE, Duennwald ML. ALS Yeast Models-Past Success Stories and New Opportunities. Frontiers in Molecular Neuroscience. 11: 394. PMID 30425620 DOI: 10.3389/Fnmol.2018.00394  0.412
2018 Zhao Y, Zurawel AA, Jenkins NP, Duennwald ML, Cheng C, Kettenbach AN, Supattapone S. Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species. Scientific Reports. 8: 9554. PMID 29934597 DOI: 10.1038/S41598-018-27900-5  0.535
2018 Di Gregorio SE, Duennwald ML. Yeast as a model to study protein misfolding in aged cells. Fems Yeast Research. 18. PMID 29905793 DOI: 10.1093/Femsyr/Foy054  0.579
2017 Lant JT, Berg MD, Sze DH, Hoffman KS, Akinpelu IC, Turk M, Heinemann IU, Duennwald ML, Brandl CJ, O'Donoghue P. Visualizing tRNA-dependent mistranslation in human cells. Rna Biology. 0. PMID 28933646 DOI: 10.1080/15476286.2017.1379645  0.378
2017 Lackie RE, Maciejewski A, Ostapchenko VG, Marques-Lopes J, Choy WY, Duennwald ML, Prado VF, Prado MAM. The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases. Frontiers in Neuroscience. 11: 254. PMID 28559789 DOI: 10.3389/Fnins.2017.00254  0.597
2016 Leach MD, Kim T, DiGregorio S, Collins C, Zhang Z, Duennwald ML, Cowen LE. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda, Md.). PMID 27807047 DOI: 10.1534/G3.116.035675  0.662
2016 Jiang Y, DiGregorio SE, Duennwald ML, Lajoie P. Polyglutamine toxicity in yeast uncovers phenotypic variations between different fluorescent protein fusions. Traffic (Copenhagen, Denmark). PMID 27734565 DOI: 10.1111/Tra.12453  0.466
2016 Zurawel AA, Kabeche R, DiGregorio SE, Deng L, Menon KM, Opalko H, Duennwald ML, Moseley JB, Supattapone S. CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins. Mbio. 7. PMID 27677791 DOI: 10.1128/Mbio.01367-16  0.558
2016 Hoffmann KS, Duennwald ML, Karagiannis J, Genereaux J, McCarton AS, Brandl CJ. Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response. G3 (Bethesda, Md.). PMID 27172216 DOI: 10.1534/G3.116.029520  0.452
2016 Chadwick SR, Demetri Pananos A, DiGregorio S, Park AE, Etedali-Zadeh P, Duennwald ML, Lajoie P. A toolbox for rapid quantitative assessment of chronological lifespan and survival in Saccharomyces cerevisiae. Traffic (Copenhagen, Denmark). PMID 26939796 DOI: 10.1111/Tra.12391  0.358
2015 Duennwald ML. Cellular stress responses in protein misfolding diseases. Future Science Oa. 1: FSO42. PMID 28031871 DOI: 10.4155/Fso.15.42  0.576
2013 Duennwald ML. Yeast as a platform to explore polyglutamine toxicity and aggregation. Methods in Molecular Biology (Clifton, N.J.). 1017: 153-61. PMID 23719914 DOI: 10.1007/978-1-62703-438-8_11  0.613
2012 Riva L, Koeva M, Yildirim F, Pirhaji L, Dinesh D, Mazor T, Duennwald ML, Fraenkel E. Poly-glutamine expanded huntingtin dramatically alters the genome wide binding of HSF1. Journal of Huntington's Disease. 1: 33-45. PMID 23293686 DOI: 10.3233/Jhd-2012-120020  0.426
2012 Duennwald ML, Echeverria A, Shorter J. Small heat shock proteins potentiate amyloid dissolution by protein disaggregases from yeast and humans. Plos Biology. 10: e1001346. PMID 22723742 DOI: 10.1371/Journal.Pbio.1001346  0.622
2012 Chafekar SM, Wisén S, Thompson AD, Echeverria A, Walter GM, Evans CG, Makley LN, Gestwicki JE, Duennwald ML. Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation. Acs Chemical Biology. 7: 1556-64. PMID 22709427 DOI: 10.1021/Cb300166P  0.556
2012 Chafekar SM, Duennwald ML. Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin. Plos One. 7: e37929. PMID 22649566 DOI: 10.1371/Journal.Pone.0037929  0.386
2012 Duennwald ML. Growth assays to assess polyglutamine toxicity in yeast. Journal of Visualized Experiments : Jove. e3461. PMID 22415521 DOI: 10.3791/3461  0.552
2011 Duennwald ML. Polyglutamine misfolding in yeast: toxic and protective aggregation. Prion. 5: 285-90. PMID 22052348 DOI: 10.4161/Pri.18071  0.587
2011 Walter GM, Smith MC, Wisén S, Basrur V, Elenitoba-Johnson KS, Duennwald ML, Kumar A, Gestwicki JE. Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes. The Journal of Biological Chemistry. 286: 40486-93. PMID 21969373 DOI: 10.1074/Jbc.M111.284448  0.439
2011 Duennwald ML. Monitoring polyglutamine toxicity in yeast. Methods (San Diego, Calif.). 53: 232-7. PMID 21144902 DOI: 10.1016/J.Ymeth.2010.12.001  0.578
2010 Duennwald ML, Shorter J. Countering amyloid polymorphism and drug resistance with minimal drug cocktails. Prion. 4: 244-51. PMID 20935457 DOI: 10.4161/Pri.4.4.13597  0.617
2009 Roberts BE, Duennwald ML, Wang H, Chung C, Lopreiato NP, Sweeny EA, Knight MN, Shorter J. A synergistic small-molecule combination directly eradicates diverse prion strain structures. Nature Chemical Biology. 5: 936-46. PMID 19915541 DOI: 10.1038/Nchembio.246  0.547
2008 Duennwald ML, Lindquist S. Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes & Development. 22: 3308-19. PMID 19015277 DOI: 10.1101/Gad.1673408  0.649
2008 Wang H, Duennwald ML, Roberts BE, Rozeboom LM, Zhang YL, Steele AD, Krishnan R, Su LJ, Griffin D, Mukhopadhyay S, Hennessy EJ, Weigele P, Blanchard BJ, King J, Deniz AA, et al. Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proceedings of the National Academy of Sciences of the United States of America. 105: 7159-64. PMID 18480256 DOI: 10.1073/Pnas.0801934105  0.718
2008 Douglas PM, Treusch S, Ren HY, Halfmann R, Duennwald ML, Lindquist S, Cyr DM. Chaperone-dependent amyloid assembly protects cells from prion toxicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 7206-11. PMID 18480252 DOI: 10.1073/Pnas.0802593105  0.747
2006 Ehrnhoefer DE, Duennwald M, Markovic P, Wacker JL, Engemann S, Roark M, Legleiter J, Marsh JL, Thompson LM, Lindquist S, Muchowski PJ, Wanker EE. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Human Molecular Genetics. 15: 2743-51. PMID 16893904 DOI: 10.1093/Hmg/Ddl210  0.682
2006 Duennwald ML, Jagadish S, Muchowski PJ, Lindquist S. Flanking sequences profoundly alter polyglutamine toxicity in yeast. Proceedings of the National Academy of Sciences of the United States of America. 103: 11045-50. PMID 16832050 DOI: 10.1073/Pnas.0604547103  0.651
2006 Duennwald ML, Jagadish S, Giorgini F, Muchowski PJ, Lindquist S. A network of protein interactions determines polyglutamine toxicity. Proceedings of the National Academy of Sciences of the United States of America. 103: 11051-6. PMID 16832049 DOI: 10.1073/Pnas.0604548103  0.669
2005 Cashikar AG, Duennwald M, Lindquist SL. A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104. The Journal of Biological Chemistry. 280: 23869-75. PMID 15845535 DOI: 10.1074/Jbc.M502854200  0.676
2004 Colby DW, Chu Y, Cassady JP, Duennwald M, Zazulak H, Webster JM, Messer A, Lindquist S, Ingram VM, Wittrup KD. Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. Proceedings of the National Academy of Sciences of the United States of America. 101: 17616-21. PMID 15598740 DOI: 10.1073/Pnas.0408134101  0.613
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