Stephan Hjorth - Publications

Affiliations: 
Integrative Pharmacology, AstraZeneca R&D, Molndal, Sweden 
Area:
CNS, appetite, serotonin, cannabinoid, in vivo

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hjorth S, Waters S, Waters N, Tedroff J, Svensson P, Fagerberg A, Edling M, Svanberg B, Ljung E, Gunnergren J, McLean SL, Grayson B, Idris NF, Neill JC, Sonesson C. . The Journal of Pharmacology and Experimental Therapeutics. PMID 32605972 DOI: 10.1124/jpet.120.000037  0.32
2020 Waters S, Sonesson C, Svensson P, Tedroff J, Carta M, Ljung E, Gunnergren J, Edling M, Svanberg B, Fagerberg A, Kullingsjo J, Hjorth S, Waters N. Preclinical pharmacology of [2-(3-fluoro-5-methanesulfonylphenoxy)ethyl](propyl)amine (IRL790), a novel dopamine transmission modulator for the treatment of motor and psychiatric complications in Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. PMID 32358046 DOI: 10.1124/jpet.119.264226  0.32
2014 Skowronski AA, Morabito MV, Mueller BR, Lee S, Hjorth S, Lehmann A, Watanabe K, Zeltser LM, Ravussin Y, Rosenbaum M, LeDuc CA, Leibel RL. Effects of a novel MC4R agonist on maintenance of reduced body weight in diet-induced obese mice. Obesity (Silver Spring, Md.). 22: 1287-95. PMID 24318934 DOI: 10.1002/oby.20678  1
2011 Wennerberg M, Cheng L, Hjorth S, Clapham JC, Balendran A, Vauquelin G. Binding properties of antagonists to cannabinoid receptors in intact cells. Fundamental & Clinical Pharmacology. 25: 200-10. PMID 20608998 DOI: 10.1111/j.1472-8206.2010.00843.x  1
2010 Boström J, Olsson RI, Tholander J, Greasley PJ, Ryberg E, Nordberg H, Hjorth S, Cheng L. Novel thioamide derivatives as neutral CB1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 479-82. PMID 20005704 DOI: 10.1016/j.bmcl.2009.11.125  1
2009 Lindström E, Ravnefjord A, Brusberg M, Hjorth S, Larsson H, Martinez V. The selective 5-hydroxytryptamine 1A antagonist, AZD7371 [3(R)-(N,N-dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide (R,R)-tartrate monohydrate] (robalzotan tartrate monohydrate), inhibits visceral pain-related visceromotor, but not autonomic cardiovascular, responses to colorectal distension in rats. The Journal of Pharmacology and Experimental Therapeutics. 329: 1048-55. PMID 19325032 DOI: 10.1124/jpet.109.152330  1
2007 Ryberg E, Larsson N, Sjögren S, Hjorth S, Hermansson NO, Leonova J, Elebring T, Nilsson K, Drmota T, Greasley PJ. The orphan receptor GPR55 is a novel cannabinoid receptor. British Journal of Pharmacology. 152: 1092-101. PMID 17876302 DOI: 10.1038/sj.bjp.0707460  1
2005 Ryberg E, Vu HK, Larsson N, Groblewski T, Hjorth S, Elebring T, Sjögren S, Greasley PJ. Identification and characterisation of a novel splice variant of the human CB1 receptor. Febs Letters. 579: 259-64. PMID 15620723 DOI: 10.1016/j.febslet.2004.11.085  1
2004 Bohlooly-Y M, Mahlapuu M, Andersén H, Astrand A, Hjorth S, Svensson L, Törnell J, Snaith MR, Morgan DG, Ohlsson C. Osteoporosis in MCHR1-deficient mice. Biochemical and Biophysical Research Communications. 318: 964-9. PMID 15147966 DOI: 10.1016/j.bbrc.2004.04.122  1
2003 Felton TM, Kang TB, Hjorth S, Auerbach SB. Effects of selective serotonin and serotonin/noradrenaline reuptake inhibitors on extracellular serotonin in rat diencephalon and frontal cortex. Naunyn-Schmiedeberg's Archives of Pharmacology. 367: 297-305. PMID 12644903 DOI: 10.1007/s00210-002-0688-x  1
2002 Wikell C, Apelqvist G, Hjorth S, Kullingsjö J, Bergqvist PB, Bengtsson F. Effects on drug disposition, brain monoamines and behavior after chronic treatment with the antidepressant venlafaxine in rats with experimental hepatic encephalopathy. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 12: 327-36. PMID 12126872 DOI: 10.1016/S0924-977X(02)00044-5  1
2001 Wikell C, Kugelberg FC, Hjorth S, Apelqvist G, Bengtsson F. Effect of halving the dose of venlafaxine to adjust for putative pharmacokinetic and pharmacodynamic changes in an animal model of chronic hepatic encephalopathy. Clinical Neuropharmacology. 24: 324-33. PMID 11801807 DOI: 10.1097/00002826-200111000-00003  1
2001 Wikell C, Hjorth S, Apelqvist G, Kullingsjö J, Lundmark J, Bergqvist PB, Bengtsson F. Sustained administration of the antidepressant venlafaxine in rats: pharmacokinetic and pharmacodynamic findings. Naunyn-Schmiedeberg's Archives of Pharmacology. 363: 448-55. PMID 11330339 DOI: 10.1007/s002100100405  1
2000 Apelqvist G, Wikell C, Carlsson B, Hjorth S, Bergqvist PB, Ahlner J, Bengtsson F. Dynamic and kinetic effects of chronic citalopram treatment in experimental hepatic encephalopathy. Clinical Neuropharmacology. 23: 304-17. PMID 11575864 DOI: 10.1097/00002826-200011000-00003  1
2000 Bengtsson HJ, Kele J, Johansson J, Hjorth S. Interaction of the antidepressant mirtazapine with alpha2-adrenoceptors modulating the release of 5-HT in different rat brain regions in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 406-12. PMID 11111835 DOI: 10.1007/s002100000294  1
2000 Hjorth S, Bengtsson HJ, Kullberg A, Carlzon D, Peilot H, Auerbach SB. Serotonin autoreceptor function and antidepressant drug action. Journal of Psychopharmacology (Oxford, England). 14: 177-85. PMID 10890313  1
2000 Hjorth S, Hutson PH. European Winter Conference on Brain Research, Plagne Lauzes, France, 6-13 March 1999. Introduction - Neuroregulation of serotoninergic systems: Basic and clinical perspectives Journal of Psychopharmacology. 14: 99.  1
1999 Wikell C, Apelqvist G, Carlsson B, Hjorth S, Bergqvist PB, Kugelberg FC, Ahlner J, Bengtsson F. Pharmacokinetic and pharmacodynamic responses to chronic administration of the selective serotonin reuptake inhibitor citalopram in rats. Clinical Neuropharmacology. 22: 327-36. PMID 10626092  1
1999 Hjorth S, Auerbach SB. Autoreceptors remain functional after prolonged treatment with a serotonin reuptake inhibitor. Brain Research. 835: 224-8. PMID 10415377 DOI: 10.1016/S0006-8993(99)01585-1  1
1998 Martin P, Carlsson ML, Hjorth S. Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats. Neuroreport. 9: 2985-8. PMID 9804302  1
1998 Wikell C, Bergqvist PB, Hjorth S, Apelqvist G, Björk H, Bengtsson F. Brain monoamine output alterations after a single venlafaxine challenge in experimental hepatic encephalopathy. Clinical Neuropharmacology. 21: 296-306. PMID 9789710  1
1998 Bengtsson HJ, Kullberg A, Millan MJ, Hjorth S. The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924. Neuropharmacology. 37: 349-56. PMID 9681933 DOI: 10.1016/S0028-3908(98)00017-3  1
1998 Hjorth S, Kullberg A, Millan MJ, Bengtsson HJ. α1-Adrenoceptor/5-hydroxytryptamine (5-HT(1A)) autoreceptor mediation of the 5-HT release-reducing action of clozapine and S16924 in rat ventral hippocampus Nordic Journal of Psychiatry. 52: 126-127.  1
1998 Wikell C, Bergqvist PBF, Apelqvist G, Hjorth S, Bengtsson F. Venlafaxine challenge alters the brain monoamine output in experimental hepatic encephalopathy[linkI] Nordic Journal of Psychiatry. 52: 124.  1
1998 Peilot H, Bengtsson HJ, Hjorth S. Regional differences in autoreceptor control of 5-hydroxytryptamine release in the rat central nervous system in vivo? Nordic Journal of Psychiatry. 52: 128.  1
1997 Bergqvist PB, Wikell C, Hjorth S, Apelqvist G, Bengtsson F. Effect of citalopram on brain serotonin release in experimental hepatic encephalopathy: implications for thymoleptic drug safety in liver insufficiency. Clinical Neuropharmacology. 20: 511-22. PMID 9403225  1
1997 Bergqvist PB, Hjorth S, Wikell C, Apelqvist G, Bengtsson F. p-Chloroamphetamine- and d-fenfluramine-induced brain serotonin release in experimental portal-systemic encephalopathy. Metabolic Brain Disease. 12: 229-36. PMID 9346471 DOI: 10.1023/B:MEBR.0000007103.82267.06  1
1997 Bergqvist PB, Hjorth S, Apelqvist G, Bengtsson F. Potassium-evoked neuronal release of serotonin in experimental chronic portal-systemic encephalopathy. Metabolic Brain Disease. 12: 193-202. PMID 9346468 DOI: 10.1023/B:MEBR.0000007100.04521.6e  1
1997 Gundlah C, Hjorth S, Auerbach SB. Autoreceptor antagonists enhance the effect of the reuptake inhibitor citalopram on extracellular 5-HT: this effect persists after repeated citalopram treatment. Neuropharmacology. 36: 475-82. PMID 9225272 DOI: 10.1016/S0028-3908(97)00052-X  1
1997 Hjorth S, Westlin D, Bengtsson HJ. WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto)receptor blocker versus that of the 5-HT reuptake inhibitor. Neuropharmacology. 36: 461-5. PMID 9225270 DOI: 10.1016/S0028-3908(97)00050-6  1
1997 Millan MJ, Hjorth S, Samanin R, Schreiber R, Jaffard R, De Ladonchamps B, Veiga S, Goument B, Peglion JL, Spedding M, Brocco M. S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)1A receptors: II. Modulation of hippocampal serotonin release in relation to potential anxiolytic properties. The Journal of Pharmacology and Experimental Therapeutics. 282: 148-61. PMID 9223550  1
1996 Bergqvist PB, Hjorth S, Audet RM, Apelqvist G, Bengtsson F, Butterworth RF. Ammonium acetate challenge in experimental chronic hepatic encephalopathy induces a transient increase of brain 5-HT release in vivo. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 6: 317-22. PMID 8985716 DOI: 10.1016/S0924-977X(96)00037-5  1
1996 Hjorth S, Bengtsson HJ, Milano S. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European Journal of Pharmacology. 316: 43-7. PMID 8982649 DOI: 10.1016/S0014-2999(96)00779-0  1
1996 Sharp T, Umbers V, Hjorth S. The role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--II NAN-190 and SDZ 216-525. Neuropharmacology. 35: 735-41. PMID 8887982 DOI: 10.1016/S0028-3908(96)00027-5  1
1996 Bergqvist PB, Hjorth S, Apelqvist G, Bengtsson F. Acute effects of L-tryptophan on brain extracellular 5-HT and 5-HIAA levels in chronic experimental portal-systemic encephalopathy. Metabolic Brain Disease. 11: 269-78. PMID 8869946  1
1996 Hjorth S. (-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine. European Journal of Pharmacology. 303: 183-6. PMID 8813565 DOI: 10.1016/0014-2999(96)00185-9  1
1996 Hjorth S, Auerbach SB. 5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI). Behavioural Brain Research. 73: 281-3. PMID 8788519 DOI: 10.1016/0166-4328(96)00113-1  1
1996 Hedberg MH, Linnanen T, Jansen JM, Nordvall G, Hjorth S, Unelius L, Johansson AM. 11-substituted (R)-aporphines: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions. Journal of Medicinal Chemistry. 39: 3503-13. PMID 8784448 DOI: 10.1021/jm960189i  1
1996 Hedberg MH, Jansen JM, Nordvall G, Hjorth S, Unelius L, Johansson AM. 10-substituted 11-oxygenated (R)-aporphines: synthesis, pharmacology, and modeling of 5-HT1A receptor interactions. Journal of Medicinal Chemistry. 39: 3491-502. PMID 8784447 DOI: 10.1021/jm960188q  1
1996 VallgÃ¥rda J, Appelberg U, Arvidsson LE, Hjorth S, Svensson BE, Hacksell U. trans-2-Aryl-N,N-dipropylcyclopropylamines: synthesis and interactions with 5-HT(1A) receptors. Journal of Medicinal Chemistry. 39: 1485-93. PMID 8691479 DOI: 10.1021/jm9507136  1
1995 Auerbach SB, Hjorth S. Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 352: 597-606. PMID 9053730 DOI: 10.1007/BF00171317  1
1995 Hedberg MH, Johansson AM, Nordvall G, Yliniemelä A, Li HB, Martin AR, Hjorth S, Unelius L, Sundell S, Hacksell U. (R)-11-hydroxy- and (R)-11-hydroxy-10-methylaporphine: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions. Journal of Medicinal Chemistry. 38: 647-58. PMID 7861413  1
1995 Hjorth S, Suchowski CS, Galloway MP. Evidence for 5-HT autoreceptor-mediated, nerve impulse-independent, control of 5-HT synthesis in the rat brain. Synapse (New York, N.Y.). 19: 170-6. PMID 7784957 DOI: 10.1002/syn.890190304  1
1995 Zhang J, Engel JA, Hjorth S, Svensson L. Changes in the acoustic startle response and prepulse inhibition of acoustic startle in rats after local injection of pertussis toxin into the ventral tegmental area. Psychopharmacology. 119: 71-8. PMID 7675952 DOI: 10.1007/BF02246056  1
1995 Auerbach SB, Lundberg JF, Hjorth S. Differential inhibition of serotonin release by 5-HT and NA reuptake blockers after systemic administration. Neuropharmacology. 34: 89-96. PMID 7623967 DOI: 10.1016/0028-3908(94)00137-H  1
1995 Hjorth S, Bengtsson HJ, Milano S, Lundberg JF, Sharp T. Studies on the role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--I. BMY7378 and prazosin. Neuropharmacology. 34: 615-20. PMID 7566497 DOI: 10.1016/0028-3908(95)00038-8  1
1995 Bergqvist PB, Vogels BA, Bosman DK, Maas MA, Hjorth S, Chamuleau RA, Bengtsson F. Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt. Journal of Neurochemistry. 64: 1238-44. PMID 7532208  1
1994 Hjorth S, Auerbach SB. Further evidence for the importance of 5-HT1A autoreceptors in the action of selective serotonin reuptake inhibitors. European Journal of Pharmacology. 260: 251-5. PMID 7988652 DOI: 10.1016/0014-2999(94)90346-8  1
1994 Hjorth S, Auerbach SB. Lack of 5-HT1A autoreceptor desensitization following chronic citalopram treatment, as determined by in vivo microdialysis. Neuropharmacology. 33: 331-4. PMID 7984270 DOI: 10.1016/0028-3908(94)90062-0  1
1994 McRae A, Ling EA, Hjorth S, Dahlström A, Mason D, Tice T. Catecholamine-containing biodegradable microsphere implants as a novel approach in the treatment of CNS neurodegenerative disease. A review of experimental studies in DA-lesioned rats. Molecular Neurobiology. 9: 191-205. PMID 7888096 DOI: 10.1007/BF02816119  1
1994 Hoffmann P, Elam M, Thorén P, Hjorth S. Effects of long-lasting voluntary running on the cerebral levels of dopamine, serotonin and their metabolites in the spontaneously hypertensive rat. Life Sciences. 54: 855-61. PMID 7511199 DOI: 10.1016/0024-3205(94)00622-9  1
1993 Hjorth S. Serotonin 5-HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study. Journal of Neurochemistry. 60: 776-9. PMID 8419553  1
1993 Galloway MP, Suchowski CS, Keegan MJ, Hjorth S. Local infusion of the selective 5HT-1b agonist CP-93,129 facilitates striatal dopamine release in vivo. Synapse (New York, N.Y.). 15: 90-2. PMID 8310427 DOI: 10.1002/syn.890150109  1
1993 Hjorth S, Sharp T. In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. The Journal of Pharmacology and Experimental Therapeutics. 265: 707-12. PMID 8098761  1
1993 Sharp T, McQuade R, Bramwell S, Hjorth S. Effect of acute and repeated administration of 5-HT1A receptor agonists on 5-HT release in rat brain in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 348: 339-46. PMID 7904048 DOI: 10.1007/BF00171331  1
1993 Söderpalm B, Lundin B, Hjorth S. Sustained 5-hydroxytryptamine release-inhibitory and anxiolytic-like action of the partial 5-HT1A receptor agonist, buspirone, after prolonged chronic administration. European Journal of Pharmacology. 239: 69-73. PMID 7901030 DOI: 10.1016/0014-2999(93)90977-P  1
1993 Hjorth S, Pettersson G. 5-HT1A autoreceptor-mediated effects of the amperozide congeners, FG5865 and FG5893, on rat brain 5-hydroxytryptamine neurochemistry in vivo. European Journal of Pharmacology. 238: 357-67. PMID 7691622 DOI: 10.1016/0014-2999(93)90867-H  1
1993 Höök BB, Johansson AM, Hjorth S, Sundell S, Hacksell U. Synthesis of (+)-(R)- and (-)-(S)-5-hydroxy-2-methyl-2-dipropylaminotetralin: effects on rat hippocampal output of 5-HT, 5-HIAA, and DOPAC as determined by in vivo microdialysis. Chirality. 5: 112-9. PMID 7687852 DOI: 10.1002/chir.530050303  1
1993 Andersson B, Wikström H, Hjorth S, Svensson K, Carlsson A, Sundell S, Lundmark M, Largent B. Resolved 2-arylcyclohexylamines: Effects on reserpine akinesia and central nervous system monoamine synthesis European Journal of Medicinal Chemistry. 28: 63-69. DOI: 10.1016/0223-5234(93)90079-T  1
1992 Hjorth S. Acute reserpine treatment increases rat brain serotonin synthesis via a nerve impulse-dependent mechanism. Journal of Neurochemistry. 58: 772-5. PMID 1530868  1
1992 Hjorth S. (-)-Penbutolol as a blocker of central 5-HT1A receptor-mediated responses. European Journal of Pharmacology. 222: 121-7. PMID 1468487 DOI: 10.1016/0014-2999(92)90471-F  1
1992 Tao R, Hjorth S. Differences in the in vitro and in vivo 5-hydroxytryptamine extraction performance among three common microdialysis membranes. Journal of Neurochemistry. 59: 1778-85. PMID 1383427 DOI: 10.1111/j.1471-4159.1992.tb11010.x  1
1992 Nissbrandt H, Hjorth S. Dopaminergic neurotransmission in somatodendritic and terminal areas of the rat brain: susceptibility to modulation by D1 and D2 receptors and to axotomy. Journal of Neural Transmission. General Section. 90: 13-26. PMID 1361343 DOI: 10.1007/BF01250514  1
1992 McRae A, Hjorth S, Dahlström A, Dillon L, Mason D, Tice T. Dopamine fiber growth induction by implantation of synthetic dopamine-containing microspheres in rats with experimental hemi-parkinsonism. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 16: 123-41. PMID 1355653 DOI: 10.1007/BF03159965  1
1992 Tao R, Hjorth S. Alpha 2-adrenoceptor modulation of rat ventral hippocampal 5-hydroxytryptamine release in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 345: 137-43. PMID 1349158 DOI: 10.1007/BF00165728  1
1992 Nissbrandt H, Waters N, Hjorth S. The influence of serotoninergic drugs on dopaminergic neurotransmission in rat substantia nigra, striatum and limbic forebrain in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 346: 12-9. PMID 1328893 DOI: 10.1007/BF00167564  1
1991 Hjorth S. Single-dose 8-OH-DPAT pretreatment does not induce tachyphylaxis to the 5-HT release-reducing effect of 5-HT1A autoreceptor agonists. European Journal of Pharmacology. 199: 237-42. PMID 1835441 DOI: 10.1016/0014-2999(91)90463-Z  1
1991 Hjorth S, Sharp T. Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis. Life Sciences. 48: 1779-86. PMID 1826937 DOI: 10.1016/0024-3205(91)90216-X  1
1991 Hjorth S, Tao R. The putative 5-HT1B receptor agonist CP-93,129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969. European Journal of Pharmacology. 209: 249-52. PMID 1797566 DOI: 10.1016/0014-2999(91)90177-R  1
1991 Ahlenius S, Hillegaart V, Hjorth S, Larsson K. Effects of sexual interactions on the in vivo rate of monoamine synthesis in forebrain regions of the male rat. Behavioural Brain Research. 46: 117-22. PMID 1786120 DOI: 10.1016/S0166-4328(05)80104-4  1
1991 McRae A, Hjorth S, Mason DW, Dillon L, Tice TR. Microencapsulated dopamine (DA)-induced restitution of function in 6-OHDA-denervated rat striatum in vivo: comparison between two microsphere excipients. Journal of Neural Transplantation & Plasticity. 2: 165-73. PMID 1782252 DOI: 10.1155/NP.1991.165  1
1990 McRae A, Hjorth S, Mason D, Dillon L, Tice T. Implantable microencapsulated dopamine (DA): prolonged functional release of DA in denervated striatal tissue. Journal of Neural Transmission. Supplementum. 29: 207-15. PMID 2358802  1
1990 Hjorth S, Sharp T. Mixed agonist/antagonist properties of NAN-190 at 5-HT1A receptors: behavioural and in vivo brain microdialysis studies. Life Sciences. 46: 955-63. PMID 2329921 DOI: 10.1016/0024-3205(90)90097-B  1
1990 Sharp T, Hjorth S. Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor. Journal of Neuroscience Methods. 34: 83-90. PMID 2259248 DOI: 10.1016/0165-0270(90)90045-H  1
1990 Hillegaart V, Hjorth S, Ahlenius S. Effects of 5-HT and 8-OH-DPAT on forebrain monoamine synthesis after local application into the median and dorsal raphe nuclei of the rat. Journal of Neural Transmission. General Section. 81: 131-45. PMID 2141990 DOI: 10.1007/BF01245833  1
1990 Sharp T, Backus LI, Hjorth S, Bramwell SR, Grahame-Smith DG. Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378. European Journal of Pharmacology. 176: 331-40. PMID 1970304 DOI: 10.1016/0014-2999(90)90027-4  1
1990 Gartside SE, Cowen PJ, Hjorth S. Effects of MDL 73005EF on central pre- and postsynaptic 5-HT1A receptor function in the rat in vivo. European Journal of Pharmacology. 191: 391-400. PMID 1964908 DOI: 10.1016/0014-2999(90)94173-U  1
1990 Hjorth S, Sharp T, Liu Y. cis-(+)-8-OH-1-CH3-DPAT, (+)ALK-3, a novel stereoselective pharmacological probe for characterizing 5-HT release-controlling 5-HT1A autoreceptors. An in vivo brain microdialysis study. Naunyn-Schmiedeberg's Archives of Pharmacology. 341: 149-57. PMID 1692973 DOI: 10.1007/BF00169724  1
1990 Hacksell U, Arvidsson LE, Johansson AM, Karlén A, Luthman K, Hjorth S. Stereoselectivity of Drug Receptor Interactions Drug Information Journal. 24: 485-496. DOI: 10.1177/009286159002400306  1
1989 Sharp T, Bramwell SR, Hjorth S, Grahame-Smith DG. Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis. British Journal of Pharmacology. 98: 989-97. PMID 2574066  1
1989 Söderpalm B, Hjorth S, Engel JA. Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test. Pharmacology, Biochemistry, and Behavior. 32: 259-65. PMID 2567524 DOI: 10.1016/0091-3057(89)90242-6  1
1989 Nissbrandt H, Sundström E, Jonsson G, Hjorth S, Carlsson A. Synthesis and release of dopamine in rat brain: comparison between substantia nigra pars compacts, pars reticulata, and striatum. Journal of Neurochemistry. 52: 1170-82. PMID 2564423  1
1989 Hjorth S, Sharp T, Hacksell U. Partial postsynaptic 5-HT1A agonist properties of the novel stereoselective 8-OH-DPAT analogue (+)cis-8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin, (+)ALK-3. European Journal of Pharmacology. 170: 269-74. PMID 2533557 DOI: 10.1016/0014-2999(89)90549-9  1
1989 Hillegaart V, Hjorth S. Median raphe, but not dorsal raphe, application of the 5-HT1A agonist 8-OH-DPAT stimulates rat motor activity. European Journal of Pharmacology. 160: 303-7. PMID 2527161 DOI: 10.1016/0014-2999(89)90505-0  1
1988 Arvidsson LE, Johansson AM, Hacksell U, Nilsson JL, Svensson K, Hjorth S, Magnusson T, Carlsson A, Lindberg P, Andersson B. N,N-Dialkylated monophenolic trans-2-phenylcyclopropylamines: novel central 5-hydroxytryptamine receptor agonists. Journal of Medicinal Chemistry. 31: 92-9. PMID 3336037  1
1988 Hjorth S, Clark D, Carlsson A. Dopamine (DA) autoreceptor efficacy of 3-PPP enantiomers after short-term synaptic DA deprivation. European Journal of Pharmacology. 152: 207-15. PMID 3146512 DOI: 10.1016/0014-2999(88)90715-7  1
1988 McRae-Degueurce A, Hjorth S, Dillon DL, Mason DW, Tice TR. Implantable microencapsulated dopamine (DA): a new approach for slow-release DA delivery into brain tissue. Neuroscience Letters. 92: 303-9. PMID 3143953 DOI: 10.1016/0304-3940(88)90607-6  1
1988 Hajos M, Hjorth S, Svensson K, Carlsson A. In vivo dopamine (DA) receptor binding and behavioural effects of the putative DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 in rats with a unilateral nigral 6-OH-DA lesion. Experimental Brain Research. 70: 577-84. PMID 3133239 DOI: 10.1007/BF00247605  1
1988 Hjorth S, Carlsson A. In vivo receptor binding, neurochemical and functional studies with the dopamine D-1 receptor antagonist SCH23390. Journal of Neural Transmission. 72: 83-97. PMID 2968439 DOI: 10.1007/BF01250232  1
1988 White FJ, Bednarz LM, Wachtel SR, Hjorth S, Brooderson RJ. Is stimulation of both D1 and D2 receptors necessary for the expression of dopamine-mediated behaviors? Pharmacology, Biochemistry, and Behavior. 30: 189-93. PMID 2902644 DOI: 10.1016/0091-3057(88)90442-X  1
1988 Hjorth S, Magnusson T. The 5-HT 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 338: 463-71. PMID 2469021 DOI: 10.1007/BF00179315  1
1987 Johansson AM, Nilsson JL, Karlén A, Hacksell U, Sanchez D, Svensson K, Hjorth S, Carlsson A, Sundell S, Kenne L. C1- and C3-methyl-substituted derivatives of 7-hydroxy-2-(di-n-propylamino)tetralin: activities at central dopamine receptors. Journal of Medicinal Chemistry. 30: 1827-37. PMID 3656358  1
1987 Ahlenius S, Carlsson A, Hillegaart V, Hjorth S, Larsson K. Region-selective activation of brain monoamine synthesis by sexual activity in the male rat. European Journal of Pharmacology. 144: 77-82. PMID 3436362 DOI: 10.1016/0014-2999(87)90011-2  1
1987 Hjorth S, Carlsson A, Engel JA. Anxiolytic-like action of the 3-PPP enantiomers in the Vogel conflict paradigm. Psychopharmacology. 92: 371-5. PMID 3114790 DOI: 10.1007/BF00210846  1
1987 Arvidsson LE, Johansson AM, Hacksell U, Nilsson JL, Svensson K, Hjorth S, Magnusson T, Carlsson A, Andersson B, Wikström H. (+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist. Journal of Medicinal Chemistry. 30: 2105-9. PMID 2959776  1
1987 Fernández-Guasti A, Ahlenius S, Hjorth S, Larsson K. Separation of dopaminergic and serotonergic inhibitory mechanisms in the mediation of estrogen-induced lordosis behaviour in the rat. Pharmacology, Biochemistry, and Behavior. 27: 93-8. PMID 2956611 DOI: 10.1016/0091-3057(87)90482-5  1
1987 Hjorth S, Carlsson A. Postsynaptic dopamine (DA) receptor stimulator properties of the putative DA autoreceptor-selective agonist B-HT 920 uncovered by co-treatment with the D-1 agonist SK&F 38393. Psychopharmacology. 93: 534-7. PMID 2893419 DOI: 10.1007/BF00207249  1
1987 Hjorth S, Söderpalm B, Engel JA. Biphasic effect of L-5-HTP in the Vogel conflict model. Psychopharmacology. 92: 96-9. PMID 2885883 DOI: 10.1007/BF00215486  1
1987 Hajós M, Hjorth S, Carlsson A. Injection of capsaicin into the nucleus raphe dorsalis elicits heat loss in the rat. Neuroscience Letters. 75: 199-204. PMID 2437500  1
1986 Svensson K, Carlsson M, Carlsson A, Hjorth S, Johansson AM, Eriksson E. The putatively selective dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 stimulate prolactin release in rats. European Journal of Pharmacology. 130: 237-42. PMID 3792447  1
1986 Hjorth S, Svensson K, Carlsson A, Wikström H, Andersson B. Central dopaminergic properties of HW-165 and its enantiomers; trans-octahydrobenzo(f)quinoline congeners of 3-PPP. Naunyn-Schmiedeberg's Archives of Pharmacology. 333: 205-18. PMID 3762735  1
1986 Hjorth S, Eriksson E, Andersson B. Stereoselective inhibition of prolactin secretion by (-)-HW-165, a novel 3-PPP congener; further support for similarities between central DA autoreceptors and pituitary lactotroph DA receptors. European Journal of Pharmacology. 125: 421-8. PMID 3755402  0.6
1986 Hacksell U, Arvidsson LE, Johansson AM, Nilsson JL, Sanchez D, Lindberg P, Wikström H, Svensson K, Hjorth S, Carlsson A. Indirect central 5-hydroxytryptaminergic actions of methoxy substituted 2-aminotetralin derivatives. Acta Pharmaceutica Suecica. 23: 77-90. PMID 3739739  1
1986 Svensson K, Hjorth S, Clark D, Carlsson A, Wikström H, Andersson B, Sanchez D, Johansson AM, Arvidsson LE, Hacksell U. (+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors. Journal of Neural Transmission. 65: 1-27. PMID 3083041  1
1986 Hjorth S, Engel JA, Carlsson A. Anticonflict effects of low doses of the dopamine agonist apomorphine in the rat. Pharmacology, Biochemistry, and Behavior. 24: 237-40. PMID 3006085 DOI: 10.1016/0091-3057(86)90344-8  1
1986 Ahlenius S, Fernandez-Guasti A, Hjorth S, Larsson K. Suppression of lordosis behavior by the putative 5-HT receptor agonist 8-OH-DPAT in the rat. European Journal of Pharmacology. 124: 361-3. PMID 2942412 DOI: 10.1016/0014-2999(86)90241-4  1
1986 Hjorth S, Carlsson A. Is pindolol a mixed agonist-antagonist at central serotonin (5-HT) receptors? European Journal of Pharmacology. 129: 131-8. PMID 2429847  1
1985 Hjorth S, Carlsson A, Clark D, Svensson K, Sanchez D. Dopamine receptor-mediated hypothermia induced in rats by (+)-, but not by (-)-3-PPP. European Journal of Pharmacology. 107: 299-304. PMID 3979430  1
1985 Wikström H, Andersson B, Sanchez D, Lindberg P, Arvidsson LE, Johansson AM, Nilsson JL, Svensson K, Hjorth S, Carlsson A. Resolved monophenolic 2-aminotetralins and 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines: structural and stereochemical considerations for centrally acting pre- and postsynaptic dopamine-receptor agonists. Journal of Medicinal Chemistry. 28: 215-25. PMID 3968686  1
1985 Hjorth S, Clark D, Svensson K, Carlsson A, Thorberg O. Sub-chronic administration of (-)-3-PPP and central dopamine receptor sensitivity changes. Journal of Neural Transmission. 64: 187-98. PMID 3936899  1
1985 Johansson AM, Arvidsson LE, Hacksell U, Nilsson JL, Svensson K, Hjorth S, Clark D, Carlsson A, Sanchez D, Andersson B. Novel dopamine receptor agonists and antagonists with preferential action on autoreceptors. Journal of Medicinal Chemistry. 28: 1049-53. PMID 3927002  1
1985 Clark D, Hjorth S, Carlsson A. Dopamine-receptor agonists: mechanisms underlying autoreceptor selectivity. I. Review of the evidence. Journal of Neural Transmission. 62: 1-52. PMID 3894582  1
1985 Hacksell U, Arvidsson LE, Johansson AM, Nilsson JL, Sanchez D, Andersson B, Lindberg P, Wikström H, Hjorth S, Svensson K. 5-Hydroxy-2-methyl-2-(di-n-propylamino)tetralin: synthesis and central pharmacological effects. Acta Pharmaceutica Suecica. 22: 65-74. PMID 2996294  0.6
1985 Hjorth S, Carlsson A. (-)-Pindolol stereospecifically inhibits rat brain serotonin (5-HT) synthesis. Neuropharmacology. 24: 1143-6. PMID 2867485  1
1985 Clark D, Hjorth S, Carlsson A. Dopamine receptor agonists: mechanisms underlying autoreceptor selectivity. II. Theoretical considerations. Journal of Neural Transmission. 62: 171-207. PMID 2863323  1
1985 Gradin K, Pettersson A, Hjorth S, Hedner T, Arvidsson LE, Persson B. Cardiovascular effects in the Sprague-Dawley rat of 8-hydroxy-2(di-N-propylamino) tetralin, a selective 5-hydroxytryptamine receptor agonist. The Journal of Pharmacy and Pharmacology. 37: 263-5. PMID 2860226  0.6
1985 Hjorth S, Clark D, Carlsson A. Lack of functional evidence for the involvement of sigma opiate receptors in the actions of the 3-PPP enantiomers on central dopaminergic systems: discrepancies between in vitro and in vivo observations. Life Sciences. 37: 673-84. PMID 2410756  1
1984 Hacksell U, Johansson AM, Arvidsson L, Nilsson JL, Hjorth S, Carlsson A, Wikström H, Sanchez D, Lindberg P. C1-Methylated 5-hydroxy-2-(dipropylamino)tetralins: central dopamine-receptor stimulating activity. Journal of Medicinal Chemistry. 27: 1003-7. PMID 6431102  1
1984 Arvidsson LE, Hacksell U, Johansson AM, Nilsson JL, Lindberg P, Sanchez D, Wikström H, Svensson K, Hjorth S, Carlsson A. 8-Hydroxy-2-(alkylamino)tetralins and related compounds as central 5-hydroxytryptamine receptor agonists. Journal of Medicinal Chemistry. 27: 45-51. PMID 6418888  1
1984 Schorderet M, Hjorth S, Hacksell U. Differential effects of the enantiomers of 3-PPP on dopamine D1-receptors of isolated rabbit retina. Journal of Neural Transmission. 59: 1-7. PMID 6325591  0.6
1984 Engel JA, Hjorth S, Svensson K, Carlsson A, Liljequist S. Anticonflict effect of the putative serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). European Journal of Pharmacology. 105: 365-8. PMID 6239785 DOI: 10.1016/0014-2999(84)90634-4  1
1984 Clark D, Hjorth S, Carlsson A. (+)- and (-)-3-PPP exhibit different intrinsic activity at striatal dopamine autoreceptors controlling dopamine synthesis. European Journal of Pharmacology. 106: 185-9. PMID 6099268  1
1984 Hjorth S, Neumeyer JL. Central monoaminergic effects of two aporphine analogues to the putative serotonin-receptor agonist, 8-hydroxy-2-di-n-propylaminotetralin. Neuropharmacology. 23: 1187-90. PMID 6097834 DOI: 10.1016/0028-3908(84)90237-5  1
1984 Wikström H, Sanchez D, Lindberg P, Hacksell U, Arvidsson LE, Johansson AM, Thorberg SO, Nilsson JL, Svensson K, Hjorth S. Resolved 3-(3-hydroxyphenyl)-N-n-propylpiperidine and its analogues: central dopamine receptor activity. Journal of Medicinal Chemistry. 27: 1030-6. PMID 6086923  0.6
1983 Hjorth S, Carlsson A, Clark D, Svensson K, Wikström H, Sanchez D, Lindberg P, Hacksell U, Arvidsson LE, Johansson A, Nilsson JL. The search for selective dopaminergic autoreceptor agonists. Journal of Neural Transmission. Supplementum. 18: 131-7. PMID 6576112  1
1983 Hjorth S, Carlsson A, Clark D, Svensson K, Wikström H, Sanchez D, Lindberg P, Hacksell U, Arvidsson LE, Johansson A. Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP. Psychopharmacology. 81: 89-99. PMID 6415751  1
1983 Clark D, Carlsson A, Hjorth S, Engel J, Lindberg P. The effect of the enantiomers of 3-PPP on conditioned avoidance responding in the rat. Psychopharmacology. 81: 14-7. PMID 6138790  1
1982 Hjorth S, Jackson D, Carlsson A, Lindberg P. A behavioral study of the changes in the CNS of mice after subchronic treatment with the dopamine autoreceptor agonist 3-PPP. Psychopharmacology Bulletin. 18: 149-52. PMID 7156279  1
1982 Wikström H, Sanchez D, Lindberg P, Arvidsson LE, Hacksell U, Johansson A, Nilsson JL, Hjorth S, Carlsson A. Monophenolic octahydrobenzo[f]quinolines: central dopamine- and serotonin-receptor stimulating activity. Journal of Medicinal Chemistry. 25: 925-31. PMID 6811743  1
1982 Jackson D, Carlsson A, Hjorth S, Lindberg P. A behavioural study of the changes in the central nervous system of mice after subchronic treatment with the selective dopamine autoreceptor agonist 3-PPP (dl-3-[3-hydroxyphenyl]-N-n-propylpiperidine). Journal of Neural Transmission. 53: 233-45. PMID 6286867  1
1982 Hjorth S, Carlsson A. Buspirone: effects on central monoaminergic transmission--possible relevance to animal experimental and clinical findings. European Journal of Pharmacology. 83: 299-303. PMID 6129148  1
1982 Clark D, Carlsson A, Hjorth S, Svensson K, Engel J, Sanchez D. Is 3-PPP a potential antipsychotic agent? Evidence from animal behavioral studies. European Journal of Pharmacology. 83: 131-4. PMID 6127226  1
1981 Hacksell U, Arvidsson LE, Svensson U, Nilsson JL, Wikström H, Lindberg P, Sanchez D, Hjorth S, Carlsson A, Paalzow L. Monophenolic 2-(dipropylamino)indans and related compounds: central dopamine-receptor stimulating activity. Journal of Medicinal Chemistry. 24: 429-34. PMID 7265130  1
1981 Hacksell U, Arvidsson LE, Svensson U, Nilsson JL, Sanchez D, Wikström H, Lindberg P, Hjorth S, Carlsson A. 3-Phenylpiperidines. Central dopamine-autoreceptor stimulating activity. Journal of Medicinal Chemistry. 24: 1475-82. PMID 6796690  1
1981 Arvidsson LE, Hacksell U, Nilsson JL, Hjorth S, Carlsson A, Lindberg P, Sanchez D, Wikstrom H. 8-Hydroxy-2-(di-n-propylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist. Journal of Medicinal Chemistry. 24: 921-3. PMID 6460101  1
1981 Ahlenius S, Larsson K, Svensson L, Hjorth S, Carlsson A, Lindberg P, Wikström H, Sanchez D, Arvidsson LE, Hacksell U, Nilsson JL. Effects of a new type of 5-HT receptor agonist on male rat sexual behavior. Pharmacology, Biochemistry, and Behavior. 15: 785-92. PMID 6458826 DOI: 10.1016/0091-3057(81)90023-X  1
1981 Hjorth S, Carlsson A, Wikström H, Lindberg P, Sanchez D, Hacksell U, Arvidsson LE, Svensson U, Nilsson JL. 3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors. Life Sciences. 28: 1225-38. PMID 6112651  1
1980 Hjorth S, Carlsson A, Lindberg P. A new centrally acting DA-receptor agonist with selectivity for autoreceptors. Psychopharmacology Bulletin. 16: 85-90. PMID 7403415  1
1979 Hacksell U, Svensson U, Nilsson JL, Hjorth S, Carlsson A, Wikström H, Lindenberg P, Sanchez D. N-Alkylated 2-aminotetralins: central dopamine-receptor stimulating activity. Journal of Medicinal Chemistry. 22: 1469-75. PMID 317109  1
1978 Wikström H, Lindberg P, Martinson P, Hjorth S, Carlsson A. Pivaloyl esters of N,N-dialkylated dopamine congeners. Central dopamine-receptor stimulating activity. Journal of Medicinal Chemistry. 21: 864-7. PMID 722753  1
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