| Year |
Citation |
Score |
| 2015 |
Villapol S, Kryndushkin D, Balarezo MG, Campbell AM, Saavedra JM, Shewmaker FP, Symes AJ. Hepatic Expression of Serum Amyloid A1 Is Induced by Traumatic Brain Injury and Modulated by Telmisartan. The American Journal of Pathology. 185: 2641-52. PMID 26435412 DOI: 10.1016/J.Ajpath.2015.06.016 |
0.593 |
|
| 2015 |
Villapol S, Balarezo MG, Affram K, Saavedra JM, Symes AJ. Neurorestoration after traumatic brain injury through angiotensin II receptor blockage. Brain : a Journal of Neurology. 138: 3299-315. PMID 26115674 DOI: 10.1093/Brain/Awv172 |
0.606 |
|
| 2013 |
Hafko R, Villapol S, Nostramo R, Symes A, Sabban EL, Inagami T, Saavedra JM. Commercially available angiotensin II Atâ‚‚ receptor antibodies are nonspecific. Plos One. 8: e69234. PMID 23840911 DOI: 10.1371/Journal.Pone.0069234 |
0.59 |
|
| 2012 |
Nostramo R, Tillinger A, Saavedra JM, Kumar A, Pandey V, Serova L, Kvetnansky R, Sabban EL. Regulation of angiotensin II type 2 receptor gene expression in the adrenal medulla by acute and repeated immobilization stress. The Journal of Endocrinology. 215: 291-301. PMID 22911895 DOI: 10.1530/Joe-12-0181 |
0.334 |
|
| 2012 |
Villapol S, Yaszemski AK, Logan TT, Sánchez-Lemus E, Saavedra JM, Symes AJ. Candesartan, an angiotensin II ATâ‚-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2817-29. PMID 22892395 DOI: 10.1038/Npp.2012.152 |
0.611 |
|
| 2011 |
Benicky J, Sánchez-Lemus E, Honda M, Pang T, Orecna M, Wang J, Leng Y, Chuang DM, Saavedra JM. Angiotensin II AT1 receptor blockade ameliorates brain inflammation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 857-70. PMID 21150913 DOI: 10.1038/Npp.2010.225 |
0.306 |
|
| 2009 |
Macova M, Pavel J, Saavedra JM. A peripherally administered, centrally acting angiotensin II AT2 antagonist selectively increases brain AT1 receptors and decreases brain tyrosine hydroxylase transcription, pituitary vasopressin and ACTH. Brain Research. 1250: 130-40. PMID 19038235 DOI: 10.1016/j.brainres.2008.11.006 |
0.335 |
|
| 2006 |
Zhou J, Pavel J, Macova M, Yu ZX, Imboden H, Ge L, Nishioku T, Dou J, Delgiacco E, Saavedra JM. AT1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats. Stroke; a Journal of Cerebral Circulation. 37: 1271-6. PMID 16601219 DOI: 10.1161/01.STR.0000217404.64352.d7 |
0.302 |
|
| 2005 |
Saavedra JM. Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities. Cellular and Molecular Neurobiology. 25: 485-512. PMID 16075377 DOI: 10.1007/s10571-005-4011-5 |
0.332 |
|
| 2004 |
Seltzer A, Bregonzio C, Armando I, Baiardi G, Saavedra JM. Oral administration of an AT1 receptor antagonist prevents the central effects of angiotensin II in spontaneously hypertensive rats. Brain Research. 1028: 9-18. PMID 15518636 DOI: 10.1016/j.brainres.2004.06.079 |
0.307 |
|
| 2004 |
Ando H, Zhou J, Macova M, Imboden H, Saavedra JM. Angiotensin II AT1 receptor blockade reverses pathological hypertrophy and inflammation in brain microvessels of spontaneously hypertensive rats. Stroke; a Journal of Cerebral Circulation. 35: 1726-31. PMID 15143297 DOI: 10.1161/01.STR.0000129788.26346.18 |
0.321 |
|
| 2003 |
Armando I, Seltzer A, Bregonzio C, Saavedra JM. Stress and angiotensin II: novel therapeutic opportunities. Current Drug Targets. Cns and Neurological Disorders. 2: 413-9. PMID 14683469 |
0.301 |
|
| 2001 |
Ito T, Nishimura Y, Saavedra J. Pre-treatment with candesartan protects from cerebral ischaemia. Journal of the Renin-Angiotensin-Aldosterone System. 2: 174-179. PMID 11881119 DOI: 10.3317/Jraas.2001.024 |
0.346 |
|
| 1989 |
Laitinen JT, Castren E, Vakkuri O, Saavedra JM. Diurnal rhythm of melatonin binding in the rat suprachiasmatic nucleus. Endocrinology. 124: 1585-7. PMID 2917527 DOI: 10.1210/endo-124-3-1585 |
0.53 |
|
| 1988 |
Gutkind JS, Kurihara M, Castren E, Saavedra JM. Increased concentration of angiotensin II binding sites in selected brain areas of spontaneously hypertensive rats. Journal of Hypertension. 6: 79-84. PMID 3351297 DOI: 10.1097/00004872-198801000-00012 |
0.595 |
|
| 1988 |
Castren E, Saavedra JM. Repeated stress increases the density of angiotensin II binding sites in rat paraventricular nucleus and subfornical organ. Endocrinology. 122: 370-2. PMID 3335214 DOI: 10.1210/endo-122-1-370 |
0.55 |
|
| 1987 |
Shigematsu K, Niwa M, Kurihara M, Castren E, Saavedra JM. Alterations in substance P binding in brain nuclei of spontaneously hypertensive rats. The American Journal of Physiology. 252: H301-6. PMID 2433950 DOI: 10.1152/Ajpheart.1987.252.2.H301 |
0.595 |
|
| 1984 |
Israel ASd, Correa F, Niwa M, Saavedra J. Quantitative measurement of angiotensin II (A II) receptors in discrete regions of rat brain, pituitary and adrenal gland by autoradiography. Clinical and Experimental Hypertension. 6: 1761-1764. PMID 6099764 DOI: 10.3109/10641968409046073 |
0.417 |
|
| 1982 |
Grobecker H, Saavedra JM, Weise VK. Biosynthetic enzyme activities and catecholamines in adrenal glands of genetic and experimental hypertensive rats. Circulation Research. 50: 742-6. PMID 6122511 DOI: 10.1042/Cs063113S |
0.369 |
|
| 1982 |
Pettinger WA, Sanchez A, Saavedra J, Haywood JR, Gandler T, Rodes T. Altered renal alpha 2-adrenergic receptor regulation in genetically hypertensive rats. Hypertension. 4: 188-192. DOI: 10.1161/01.Hyp.4.3_Pt_2.188 |
0.328 |
|
| 1979 |
Paul SM, Axelrod J, Saavedra JM, Skolnick P. Estrogen-induced efflux of endogenous catecholamines from the hypothalamus in vitro. Brain Research. 178: 499-505. PMID 228795 DOI: 10.1016/0006-8993(79)90709-1 |
0.378 |
|
| 1978 |
Saavedra JM, Grobecker H, Axelrod J. Changes in central catecholaminergic neurons in the spontaneously (genetic) hypertensive rat. Circulation Research. 42: 529-34. PMID 630670 DOI: 10.1161/01.Res.42.4.529 |
0.511 |
|
| 1977 |
Kebabian JW, Saavedra JM, Axelrod J. A sensitive enzymatic-radioisotopic assay for 3,4-dihydroxyphenylacetic acid. Journal of Neurochemistry. 28: 795-801. PMID 894287 DOI: 10.1111/J.1471-4159.1977.Tb10630.X |
0.342 |
|
| 1977 |
Saavedra JM, Grobecker H, Axelrod J. Biochemical and morphologic study of catecholamine metabolism in spontaneously hypertensive rats. Mayo Clinic Proceedings. 52: 391-4. PMID 865135 |
0.522 |
|
| 1977 |
Axelrod J, Saavedra JM. Octopamine. Nature. 265: 501-4. PMID 13310 DOI: 10.1038/265501a0 |
0.388 |
|
| 1976 |
Saavedra JM, Grobecker H, Axelrod J. Adrenaline-forming enzyme in brainstem: elevation in genetic and experimental hypertension. Science (New York, N.Y.). 191: 483-4. PMID 1246633 DOI: 10.1126/Science.1246633 |
0.421 |
|
| 1976 |
Tallman JF, Saavedra JM, Axelrod J. A sensitive enzymatic-isotopic method for the analysis of tyramine in brain and other tissues. Journal of Neurochemistry. 27: 465-9. PMID 965987 DOI: 10.1111/J.1471-4159.1976.Tb12269.X |
0.659 |
|
| 1976 |
Saavedra JM, Axelrod J. Octopamine as a putative neurotransmitter. Advances in Biochemical Psychopharmacology. 15: 95-110. PMID 799466 |
0.389 |
|
| 1976 |
Grobecker H, Saavedra JM, Roizen MF, Weise V, Kopin IJ, Axelrod J. Peripheral and central catecholaminergic neurons in genetic and experimental hypertension in rats. Clinical Science and Molecular Medicine. Supplement. 3: 377s-380s. PMID 15756 DOI: 10.1042/Cs051377S |
0.483 |
|
| 1976 |
Tallman JF, Saavedra JM, Axelrod J. Biosynthesis and metabolism of endogenous tyramine and its normal presence in sympathetic nerves. The Journal of Pharmacology and Experimental Therapeutics. 199: 216-21. PMID 10424 |
0.658 |
|
| 1975 |
Wooten GF, Jacobowitz DM, Saavedra JM, Axelrod J. Localization of extraneuronal dopamine-beta-hydroxylase in rat salivary gland by immunofluorescence histochemistry. Journal of Neurochemistry. 24: 1107-10. PMID 1092811 DOI: 10.1111/J.1471-4159.1975.Tb03884.X |
0.39 |
|
| 1974 |
Saavedra JM, Palkovits M, Brownstein MJ, Axelrod J. Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region. Brain Research. 77: 157-65. PMID 4854251 DOI: 10.1016/0006-8993(74)90812-9 |
0.441 |
|
| 1974 |
Palkovits M, Brownstein M, Saavedra JM, Axelrod J. Norepinephrine and dopamine content of hypothalamic nuclei of the rat. Brain Research. 77: 137-49. PMID 4853370 DOI: 10.1016/0006-8993(74)90810-5 |
0.427 |
|
| 1974 |
Saavedra JM, Palkovits M, Brownstein MJ, Axelrod J. Localisation of phenylethanolamine N-methyl transferase in the rat brain nuclei. Nature. 248: 695-6. PMID 4833273 DOI: 10.1038/248695A0 |
0.521 |
|
| 1974 |
Saavedra JM, Axelrod J. Enzymatic-isotopic micromethods for the measurement of biogenic amines in brain tissue and body fluids Journal of Psychiatric Research. 11: 289-291. PMID 4618286 DOI: 10.1016/0022-3956(74)90108-3 |
0.434 |
|
| 1974 |
Brownstein MJ, Saavedra JM, Axelrod J, Zeman GH, Carpenter DO. Coexistence of several putative neurotransmitters in single identified neurons of Aplysia. Proceedings of the National Academy of Sciences of the United States of America. 71: 4662-5. PMID 4373726 DOI: 10.1073/Pnas.71.12.4662 |
0.345 |
|
| 1974 |
Saavedra JM, Axelrod J. Brain tryptamine and the effects of drugs Advances in Biochemical Psychopharmacology. 10: 135-139. PMID 4276952 |
0.407 |
|
| 1974 |
Brownstein MJ, Saavedra JM, Palkovits M, Axelrod J. Histamine content of hypothalamic nuclei of the rat. Brain Research. 77: 151-6. PMID 4212053 DOI: 10.1016/0006-8993(74)90811-7 |
0.446 |
|
| 1974 |
Saavedra JM, Brownstein M, Palkovits M, Kizer S, Axelrod J. Tyrosine hydroxylase and dopamine-beta-hydroxylase: distribution in the individual rat hypothalamic nuclei. Journal of Neurochemistry. 23: 869-71. PMID 4154360 DOI: 10.1111/j.1471-4159.1974.tb04416.x |
0.427 |
|
| 1974 |
Saavedra JM, Coyle JT, Axelrod J. Developmental characteristics of phenylethanolamine and octopamine in the rat brain. Journal of Neurochemistry. 23: 511-5. PMID 4153859 |
0.594 |
|
| 1974 |
Saavedra JM, Brownstein MJ, Carpenter DO, Axelrod J. Octopamine: presence in single neurons of Aplysia suggests neurotransmitter function. Science (New York, N.Y.). 185: 364-5. PMID 4151812 DOI: 10.1126/science.185.4148.364 |
0.355 |
|
| 1973 |
Saavedra JM, Brownstein M, Axelrod J. A specific and sensitive enzymatic-isotopic microassay for serotonin in tissues. The Journal of Pharmacology and Experimental Therapeutics. 186: 508-15. PMID 4728332 |
0.358 |
|
| 1973 |
Saavedra JM, Coyle JT, Axelrod J. The distribution and properties of the nonspecific N-methyltransferase in brain. Journal of Neurochemistry. 20: 743-52. PMID 4703789 |
0.531 |
|
| 1973 |
Wyatt RJ, Saavedra JM, Axelrod J. A dimethyltryptamine-forming enzyme in human blood. The American Journal of Psychiatry. 130: 754-60. PMID 4514540 DOI: 10.1176/Ajp.130.7.754 |
0.453 |
|
| 1973 |
Saavedra JM, Axelrod J. Demonstration and distribution of phenylethanolamine in brain and other tissues Proceedings of the National Academy of Sciences of the United States of America. 70: 769-772. PMID 4268476 DOI: 10.1073/Pnas.70.3.769 |
0.519 |
|
| 1973 |
Saavedra JM, Axelrod J. Effect of drugs on the tryptamine content of rat tissues Journal of Pharmacology and Experimental Therapeutics. 185: 523-529. PMID 4268231 |
0.484 |
|
| 1973 |
Brownstein M, Saavedra JM, Axelrod J. Control of pineal N-acetylserotonin by a beta adrenergic receptor. Molecular Pharmacology. 9: 605-11. PMID 4150902 |
0.345 |
|
| 1972 |
Saavedra JM, Axelrod J. Psychotomimetic N-methylated tryptamines: Formation in brain in vivo and in vitro Science. 175: 1365-1366. PMID 5059565 DOI: 10.1126/Science.175.4028.1365 |
0.489 |
|
| 1972 |
Saavedra JM, Axelrod J. A specific and sensitive enzymatic assay for tryptamine in tissues Journal of Pharmacology and Experimental Therapeutics. 182: 363-369. PMID 5055399 |
0.356 |
|
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