Irwin J. Kopin - Publications

Affiliations: 
National Institute of Neurological Disorders and Stroke, Bethesda, MD, United States 
Area:
Dopamine, Parkinson's Disease

288 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Goldstein DS, Sullivan P, Holmes C, Kopin IJ, Sharabi Y, Mash DC. Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophy. Parkinsonism & Related Disorders. 21: 567-72. PMID 25829070 DOI: 10.1016/j.parkreldis.2015.03.006  1
2015 Goldstein DS, Sullivan P, Cooney A, Jinsmaa Y, Kopin IJ, Sharabi Y. Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease. Journal of Neurochemistry. 133: 14-25. PMID 25645689 DOI: 10.1111/jnc.13042  1
2015 Goldstein DS, Kopin IJ, Sharabi Y, Holmes C. Plasma biomarkers of decreased vesicular storage distinguish Parkinson disease with orthostatic hypotension from the parkinsonian form of multiple system atrophy. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. 25: 61-7. PMID 25638582 DOI: 10.1007/s10286-015-0268-z  1
2015 Goldstein DS, Holmes C, Sullivan P, Mash DC, Sidransky E, Stefani A, Kopin IJ, Sharabi Y. Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration Parkinsonism and Related Disorders. DOI: 10.1016/j.parkreldis.2015.07.009  1
2014 Goldstein DS, Kopin IJ, Sharabi Y. Catecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disorders. Pharmacology & Therapeutics. 144: 268-82. PMID 24945828 DOI: 10.1016/j.pharmthera.2014.06.006  1
2014 Goldstein DS, Sullivan P, Holmes C, Miller GW, Sharabi Y, Kopin IJ. A vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's disease. Journal of Neurochemistry. PMID 24848581 DOI: 10.1111/jnc.12766  1
2013 Goldstein DS, Sullivan P, Holmes C, Miller GW, Alter S, Strong R, Mash DC, Kopin IJ, Sharabi Y. Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease. Journal of Neurochemistry. 126: 591-603. PMID 23786406 DOI: 10.1111/jnc.12345  1
2012 Goldstein DS, Sullivan P, Cooney A, Jinsmaa Y, Sullivan R, Gross DJ, Holmes C, Kopin IJ, Sharabi Y. Vesicular uptake blockade generates the toxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde in PC12 cells: relevance to the pathogenesis of Parkinson's disease. Journal of Neurochemistry. 123: 932-43. PMID 22906103 DOI: 10.1111/j.1471-4159.2012.07924.x  1
2011 Goldstein DS, Holmes C, Kopin IJ, Sharabi Y. Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases. The Journal of Clinical Investigation. 121: 3320-30. PMID 21785221 DOI: 10.1172/JCI45803  1
2011 Goldstein DS, Sullivan P, Holmes C, Kopin IJ, Basile MJ, Mash DC. Catechols in post-mortem brain of patients with Parkinson disease. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 18: 703-10. PMID 21073636 DOI: 10.1111/j.1468-1331.2010.03246.x  1
2011 Goldstein DS, Holmes C, Sewell L, Pechnik S, Kopin IJ. Effects of carbidopa and entacapone on the metabolic fate of the norepinephrine prodrug L-DOPS. Journal of Clinical Pharmacology. 51: 66-74. PMID 20220040 DOI: 10.1177/0091270010363476  1
2009 Eisenhofer G, Goldstein D, Kopin I. Simultaneous liquid-chromatographic determination of plasma catecholamines and metabolites Clinical Chemistry. 55: 2223-2224. PMID 19833834 DOI: 10.1373/clinchem.2009.134478  1
2009 Goldstein DS, Holmes C, Sewell L, Kopin IJ. Hypertension increases cerebral 6-18F-fluorodopa-derived radioactivity. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1479-82. PMID 19690020 DOI: 10.2967/jnumed.109.062869  1
2008 Goldstein DS, Kopin IJ. Adrenomedullary, adrenocortical, and sympathoneural responses to stressors: a meta-analysis. Endocrine Regulations. 42: 111-9. PMID 18999898  1
2007 Goldstein DS, Kopin IJ. Evolution of concepts of stress. Stress (Amsterdam, Netherlands). 10: 109-20. PMID 17514579 DOI: 10.1080/10253890701288935  1
2006 Kopin IJ. The relationship of early studies of monoamine oxidase to present concepts. Journal of Neural Transmission. Supplementum. 79-86. PMID 17447418  1
2006 Goldstein DS, Eisenhofer G, Kopin IJ. Clinical catecholamine neurochemistry: a legacy of Julius Axelrod. Cellular and Molecular Neurobiology. 26: 695-702. PMID 16871444 DOI: 10.1007/s10571-006-9041-0  1
2004 Eisenhofer G, Kopin IJ, Goldstein DS. Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacological Reviews. 56: 331-49. PMID 15317907 DOI: 10.1124/pr.56.3.1  1
2004 Eisenhofer G, Kopin IJ, Goldstein DS. Leaky catecholamine stores: undue waste or a stress response coping mechanism? Annals of the New York Academy of Sciences. 1018: 224-30. PMID 15240373 DOI: 10.1196/annals.1296.027  1
2004 Eldadah BA, Pacak K, Eisenhofer G, Holmes C, Kopin IJ, Goldstein DS. Cardiac uptake-1 inhibition by high circulating norepinephrine levels in patients with pheochromocytoma. Hypertension. 43: 1227-32. PMID 15078865 DOI: 10.1161/01.HYP.0000127305.87552.d6  1
2003 Eisenhofer G, Goldstein DS, Kopin IJ, Crout JR. Pheochromocytoma: rediscovery as a catecholamine-metabolizing tumor. Endocrine Pathology. 14: 193-212. PMID 14586065 DOI: 10.1385/EP:14:3:193  1
2003 Li ST, Holmes C, Kopin IJ, Goldstein DS. Aging-related changes in cardiac sympathetic function in humans, assessed by 6-18F-fluorodopamine PET scanning. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 44: 1599-603. PMID 14530473  1
2003 Goldstein DS, Eisenhofer G, Kopin IJ. Sources and significance of plasma levels of catechols and their metabolites in humans. The Journal of Pharmacology and Experimental Therapeutics. 305: 800-11. PMID 12649306 DOI: 10.1124/jpet.103.049270  1
2003 Goldstein DS, Holmes C, Patronas N, Kopin IJ. Cerebrospinal fluid levels of catechols in patients with neurogenic orthostatic hypotension. Clinical Science (London, England : 1979). 104: 649-54. PMID 12540289 DOI: 10.1042/CS20020315  1
2003 Hassan M, Hattery D, Chernomordik V, Toda K, Fukuhara K, Mittal D, Rowan J, Shah J, Gerber L, Dionne R, Kopin I, Gandjbakhche AH. Infrared thermographic imaging for the assessment of temperature asymmetries in reflex sympathetic dystrophy Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 1102-1105.  1
2002 Kawamura M, Eisenhofer G, Kopin IJ, Kador PF, Lee YS, Fujisawa S, Sato S. Aldose reductase: an aldehyde scavenging enzyme in the intraneuronal metabolism of norepinephrine in human sympathetic ganglia. Autonomic Neuroscience : Basic & Clinical. 96: 131-9. PMID 11958479 DOI: 10.1016/S1566-0702(01)00385-X  1
2002 Goldstein DS, Katzper M, Linares O, Kopin IJ. Kinetic model for the fate of 6-[18F]fluorodopamine in the human heart: a novel means to examine cardiac sympathetic neuronal function. Naunyn-Schmiedeberg's Archives of Pharmacology. 365: 38-49. PMID 11862332 DOI: 10.1007/s002100100426  1
2001 Goldstein DS, Li ST, Kopin IJ. Sympathetic neurocirculatory failure in Parkinson disease: Evidence for an etiologic role of alpha-synuclein. Annals of Internal Medicine. 135: 1010-1. PMID 11730415  1
2000 Yadid G, Harvey-White JD, Kopin IJ, Goldstein DS. Estimation of striatal dopamine spillover and metabolism in vivo. Neuroreport. 11: 3367-73. PMID 11059904  1
2000 Lamensdorf I, Hrycyna C, He LP, Nechushtan A, Tjurmina O, Harvey-White J, Eisenhofer G, Rojas E, Kopin IJ. Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter. Naunyn-Schmiedeberg's Archives of Pharmacology. 361: 654-64. PMID 10882041 DOI: 10.1007/s002100000246  1
2000 Lamensdorf I, Eisenhofer G, Harvey-White J, Nechustan A, Kirk K, Kopin IJ. 3,4-Dihydroxyphenylacetaldehyde potentiates the toxic effects of metabolic stress in PC12 cells. Brain Research. 868: 191-201. PMID 10854571 DOI: 10.1016/S0006-8993(00)02309-X  1
2000 Lamensdorf I, Eisenhofer G, Harvey-White J, Hayakawa Y, Kirk K, Kopin IJ. Metabolic stress in PC12 cells induces the formation of the endogenous dopaminergic neurotoxin, 3,4-dihydroxyphenylacetaldehyde. Journal of Neuroscience Research. 60: 552-8. PMID 10797558 DOI: 10.1002/(SICI)1097-4547(20000515)60:4<552::AID-JNR14>3.0.CO;2-U  1
2000 Lamensdorf I, He L, Nechushtan A, Harvey-White J, Eisenhofer G, Milan R, Rojas E, Kopin IJ. Effect of glipizide on dopamine synthesis, release and metabolism in PC12 cells. European Journal of Pharmacology. 388: 147-54. PMID 10666506 DOI: 10.1016/S0014-2999(99)00839-0  1
1999 Duan YF, Kopin IJ, Goldstein DS. Stimulation of the paraventricular nucleus modulates firing of neurons in the nucleus of the solitary tract. The American Journal of Physiology. 277: R403-11. PMID 10444546  1
1999 Kawamura M, Eisenhofer G, Kopin IJ, Kador PF, Lee YS, Tsai JY, Fujisawa S, Lizak MJ, Sinz A, Sato S. Aldose reductase, a key enzyme in the oxidative deamination of norepinephrine in rats. Biochemical Pharmacology. 58: 517-24. PMID 10424772 DOI: 10.1016/S0006-2952(99)00121-5  1
1999 Sato S, Kawamura M, Eisenhofer G, Kopin IJ, Fujisawa S, Kador PF. Aldo-keto reductases in norepinephrine metabolism. Advances in Experimental Medicine and Biology. 463: 459-63. PMID 10352719  1
1999 Tjurmina OA, Goldstein DS, Palkovits M, Kopin IJ. Alpha2-adrenoceptor-mediated restraint of norepinephrine synthesis, release, and turnover during immobilization in rats. Brain Research. 826: 243-52. PMID 10224302 DOI: 10.1016/S0006-8993(99)01281-0  1
1999 Lamensdorf I, Meiri N, Harvey-White J, Jacobowitz DM, Kopin IJ. Kir6.2 oligoantisense administered into the globus pallidus reduces apomorphine-induced turning in 6-OHDA hemiparkinsonian rats. Brain Research. 818: 275-84. PMID 10082813 DOI: 10.1016/S0006-8993(98)01290-6  1
1999 Kawamura M, Schwartz JP, Nomura T, Kopin IJ, Goldstein DS, Huynh TT, Hooper DR, Harvey-White J, Eisenhofer G. Differential effects of chemical sympathectomy on expression and activity of tyrosine hydroxylase and levels of catecholamines and DOPA in peripheral tissues of rats. Neurochemical Research. 24: 25-32. PMID 9973233 DOI: 10.1023/A:1020919828028  1
1998 Pacak K, Palkovits M, Yadid G, Kvetnansky R, Kopin IJ, Goldstein DS. Heterogeneous neurochemical responses to different stressors: a test of Selye's doctrine of nonspecificity. The American Journal of Physiology. 275: R1247-55. PMID 9756557  1
1998 Al-Damluji S, Kopin IJ. Structural properties of phenylethylamine derivatives which inhibit transport-P in peptidergic neurones. British Journal of Pharmacology. 124: 693-702. PMID 9690861 DOI: 10.1038/sj.bjp.0701894  1
1998 Kopin IJ, Rundqvist B, Friberg P, Lenders J, Goldstein DS, Eisenhofer G. Different relationships of spillover to release of norepinephrine in human heart, kidneys, and forearm. The American Journal of Physiology. 275: R165-73. PMID 9688975  1
1998 Castillo SO, Baffi JS, Palkovits M, Goldstein DS, Kopin IJ, Witta J, Magnuson MA, Nikodem VM. Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Molecular and Cellular Neurosciences. 11: 36-46. PMID 9608532 DOI: 10.1006/mcne.1998.0673  1
1998 Finberg JP, Wang J, Bankiewicz K, Harvey-White J, Kopin IJ, Goldstein DS. Increased striatal dopamine production from L-DOPA following selective inhibition of monoamine oxidase B by R(+)-N-propargyl-1-aminoindan (rasagiline) in the monkey. Journal of Neural Transmission. Supplementum. 52: 279-85. PMID 9564628  1
1998 Axelrod FB, Goldstein DS, Holmes C, Kopin IJ. Genotype and phenotype in familial dysautonomia. Advances in Pharmacology (San Diego, Calif.). 42: 925-8. PMID 9328049 DOI: 10.1016/S1054-3589(08)60898-4  1
1998 Goldstein DS, Holmes C, Cannon RO, Eisenhofer G, Kopin IJ. Sympathetic cardioneuropathy in dysautonomias. Advances in Pharmacology (San Diego, Calif.). 42: 615-9. PMID 9327977  1
1998 Kvetnanský R, Pacák K, Sabban EL, Kopin IJ, Goldstein DS. Stressor specificity of peripheral catecholaminergic activation. Advances in Pharmacology (San Diego, Calif.). 42: 556-60. PMID 9327962 DOI: 10.1016/S1054-3589(08)60811-X  1
1997 Kawamura M, Kopin IJ, Kador PF, Sato S, Tjurmina O, Eisenhofer G. Effects of aldehyde/aldose reductase inhibition on neuronal metabolism of norepinephrine. Journal of the Autonomic Nervous System. 66: 145-8. PMID 9406118 DOI: 10.1016/S0165-1838(97)00086-6  1
1997 Hooper D, Kawamura M, Hoffman B, Kopin IJ, Hunyady B, Mezey E, Eisenhofer G. Tyrosine hydroxylase assay for detection of low levels of enzyme activity in peripheral tissues. Journal of Chromatography. B, Biomedical Sciences and Applications. 694: 317-24. PMID 9252045 DOI: 10.1016/S0378-4347(97)00166-7  1
1997 Schatz J, Low P, Polinskyd RJ, Goldstien D, Eisenhofer G, Kopin IJ. Disorders of the autonomic nervous system [4] (multiple letters) New England Journal of Medicine. 337: 278-280. PMID 9229696 DOI: 10.1056/NEJM199707243370415  1
1997 Herzberg U, Eliav E, Dorsey JM, Gracely RH, Kopin IJ. NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve. Neuroreport. 8: 1613-8. PMID 9189901  1
1997 Herzberg U, Eliav E, Bennett GJ, Kopin IJ. The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain. Neuroscience Letters. 221: 157-60. PMID 9121688 DOI: 10.1016/S0304-3940(96)13308-5  1
1997 Goldstein DS, Holmes C, Stuhlmuller JE, Lenders JW, Kopin IJ. 6-[18F]fluorodopamine positron emission tomographic scanning in the assessment of cardiac sympathoneural function--studies in normal humans. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. 7: 17-29. PMID 9074825 DOI: 10.1007/BF02267622  1
1997 Goldstein DS, Holmes C, Cannon RO, Eisenhofer G, Kopin IJ. Sympathetic cardioneuropathy in dysautonomias. The New England Journal of Medicine. 336: 696-702. PMID 9041100 DOI: 10.1056/NEJM199703063361004  1
1997 Goldstein DS, Holmes C, Cannon RO, Eisenhofer G, Kopin IJ. Sympathetic Carondioneuropathy in Dysautonomias Advances in Pharmacology. 42: 615-619. DOI: 10.1016/S1054-3589(08)60826-1  1
1996 Higgins JJ, Harvey-White JD, Nee LE, Colli MJ, Grossi TA, Kopin IJ. Brain MRI, lumbar CSF monoamine concentrations, and clinical descriptors of patients with spinocerebellar ataxia mutations. Journal of Neurology, Neurosurgery, and Psychiatry. 61: 591-5. PMID 8971105  1
1996 Fukuhara K, Kvetnansky R, Weise VK, Ohara H, Yoneda R, Goldstein DS, Kopin IJ. Effects of continuous and intermittent cold (SART) stress on sympathoadrenal system activity in rats. Journal of Neuroendocrinology. 8: 65-72. PMID 8932738 DOI: 10.1111/j.1365-2826.1996.tb00687.x  1
1996 Axelrod FB, Goldstein DS, Holmes C, Berlin D, Kopin IJ. Pattern of plasma levels of catecholamines in familial dysautonomia. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. 6: 205-9. PMID 8902316 DOI: 10.1007/BF02291135  1
1996 Yamamoto T, Polinsky RJ, Goldstein DS, Baucom CE, Kopin IJ. Plasma sulfoconjugated dopamine levels are normal in patients with autonomic failure. The Journal of Laboratory and Clinical Medicine. 128: 488-91. PMID 8900291  1
1996 Eisenhofer G, Lenders JW, Harvey-White J, Ernst M, Zametkin A, Murphy DL, Kopin IJ. Differential inhibition of neuronal and extraneuronal monoamine oxidase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 296-301. PMID 8873113 DOI: 10.1016/0893-133X(95)00233-4  1
1996 Al-Damluji S, Kopin IJ. Binding and competitive inhibition of amine uptake at postsynaptic neurones (transport-P) by tricyclic antidepressants. British Journal of Pharmacology. 117: 811-6. PMID 8851495  1
1996 Pacak K, Palkovits M, Makino S, Kopin IJ, Goldstein DS. Brainstem hemisection decreases corticotropin-releasing hormone mRNA in the paraventricular nucleus but not in the central amygdaloid nucleus. Journal of Neuroendocrinology. 8: 543-51. PMID 8843023 DOI: 10.1046/j.1365-2826.1996.04888.x  1
1996 Fukuhara K, Kvetnansky R, Cizza G, Pacak K, Ohara H, Goldstein DS, Kopin IJ. Interrelations between sympathoadrenal system and hypothalamo-pituitary-adrenocortical/thyroid systems in rats exposed to cold stress. Journal of Neuroendocrinology. 8: 533-41. PMID 8843022 DOI: 10.1046/j.1365-2826.1996.04877.x  1
1996 Al-Damluji S, Kopin IJ. Functional properties of the uptake of amines in immortalised peptidergic neurones (transport-P). British Journal of Pharmacology. 117: 111-8. PMID 8825351  1
1996 Eisenhofer G, Friberg P, Rundqvist B, Quyyumi AA, Lambert G, Kaye DM, Kopin IJ, Goldstein DS, Esler MD. Cardiac sympathetic nerve function in congestive heart failure. Circulation. 93: 1667-76. PMID 8653872  1
1996 Lenders JW, Eisenhofer G, Abeling NG, Berger W, Murphy DL, Konings CH, Wagemakers LM, Kopin IJ, Karoum F, van Gennip AH, Brunner HG. Specific genetic deficiencies of the A and B isoenzymes of monoamine oxidase are characterized by distinct neurochemical and clinical phenotypes. The Journal of Clinical Investigation. 97: 1010-9. PMID 8613523 DOI: 10.1172/JCI118492  1
1996 Kvetnanský R, Nankova B, Hiremagalur B, Viskupic E, Vietor I, Rusnak M, McMahon A, Kopin IJ, Sabban EL. Induction of adrenal tyrosine hydroxylase mRNA by single immobilization stress occurs even after splanchnic transection and in the presence of cholinergic antagonists. Journal of Neurochemistry. 66: 138-46. PMID 8522945  1
1995 Chang PC, Grossman E, Kopin IJ, Goldstein DS, Folio CJ, Holmes C. On the existence of functional angiotensin II receptors on vascular sympathetic nerve terminals in the human forearm. Journal of Hypertension. 13: 1275-84. PMID 8984125  1
1995 Kopin IJ. Definitions of stress and sympathetic neuronal responses. Annals of the New York Academy of Sciences. 771: 19-30. PMID 8597398 DOI: 10.1111/j.1749-6632.1995.tb44667.x  1
1995 Kvetnanský R, Pacák K, Fukuhara K, Viskupic E, Hiremagalur B, Nankova B, Goldstein DS, Sabban EL, Kopin IJ. Sympathoadrenal system in stress. Interaction with the hypothalamic-pituitary-adrenocortical system. Annals of the New York Academy of Sciences. 771: 131-58. PMID 8597393 DOI: 10.1111/j.1749-6632.1995.tb44676.x  1
1995 Pacák K, Palkovits M, Kvetnanský R, Yadid G, Kopin IJ, Goldstein DS. Effects of various stressors on in vivo norepinephrine release in the hypothalamic paraventricular nucleus and on the pituitary-adrenocortical axis. Annals of the New York Academy of Sciences. 771: 115-30. PMID 8597392 DOI: 10.1111/j.1749-6632.1995.tb44675.x  1
1995 Pacak K, McCarty R, Palkovits M, Kopin IJ, Goldstein DS. Effects of immobilization on in vivo release of norepinephrine in the bed nucleus of the stria terminalis in conscious rats. Brain Research. 688: 242-6. PMID 8542318 DOI: 10.1016/0006-8993(95)00566-9  1
1995 Cizza G, Pacak K, Kvetnansky R, Palkovits M, Goldstein DS, Brady LS, Fukuhara K, Bergamini E, Kopin IJ, Blackman MR. Decreased stress responsivity of central and peripheral catecholaminergic systems in aged 344/N Fischer rats. The Journal of Clinical Investigation. 95: 1217-24. PMID 7883970 DOI: 10.1172/JCI117771  1
1995 Yadid G, Goldstein DS, Pacak K, Kopin IJ, Golomb E. Functional alpha 3-glycine receptors in rat adrenal. European Journal of Pharmacology. 288: 399-401. PMID 7774687 DOI: 10.1016/0922-4106(95)90056-X  1
1995 Pacak K, McCarty R, Palkovits M, Cizza G, Kopin IJ, Goldstein DS, Chrousos GP. Decreased central and peripheral catecholaminergic activation in obese Zucker rats. Endocrinology. 136: 4360-7. PMID 7664655 DOI: 10.1210/endo.136.10.7664655  1
1995 Finberg JP, Wang J, Goldstein DS, Kopin IJ, Bankiewicz KS. Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats. Journal of Neurochemistry. 65: 1213-20. PMID 7643100  1
1995 Pacak K, Palkovits M, Kopin IJ, Goldstein DS. Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: in vivo microdialysis studies. Frontiers in Neuroendocrinology. 16: 89-150. PMID 7621982 DOI: 10.1006/frne.1995.1004  1
1995 Pacak K, Palkovits M, Kvetnansky R, Matern P, Hart C, Kopin IJ, Goldstein DS. Catecholaminergic inhibition by hypercortisolemia in the paraventricular nucleus of conscious rats. Endocrinology. 136: 4814-9. PMID 7588211 DOI: 10.1210/endo.136.11.7588211  1
1995 Eisenhofer G, Rundquist B, Aneman A, Friberg P, Dakak N, Kopin IJ, Jacobs MC, Lenders JW. Regional release and removal of catecholamines and extraneuronal metabolism to metanephrines. The Journal of Clinical Endocrinology and Metabolism. 80: 3009-17. PMID 7559889 DOI: 10.1210/jcem.80.10.7559889  1
1995 Higgins JJ, Harvey-White JD, Kopin IJ. Low lumbar CSF concentrations of homovanillic acid in the autosomal dominant ataxias. Journal of Neurology, Neurosurgery, and Psychiatry. 58: 760. PMID 7541830  1
1995 Wolfovitz E, Pacak K, Abassi Z, Kopin IJ, Goldstein DS. Effects of hypercortisolemia or hyperinsulinemia on neurochemical indices of catecholamine release and synthesis in conscious rats. Journal of the Autonomic Nervous System. 54: 104-12. PMID 7499722 DOI: 10.1016/0165-1838(94)00192-M  1
1995 Schildkraut JJ, Kopin IJ, Schanberg SM, Durell J. Norepinephrine metabolism and psychoactive drugs in the endogenous depressions. 1968. Pharmacopsychiatry. 28: 24-37. PMID 7480108 DOI: 10.1055/s-2007-979616  1
1994 Kvetnansky R, Noskov VB, Blazicek P, Macho L, Grigoriev AI, Goldstein DS, Kopin IJ. New approaches to evaluate sympathoadrenal system activity in experiments on earth and in space. Acta Astronautica. 34: 243-54. PMID 11540743 DOI: 10.1016/0094-5765(94)90261-5  1
1994 Miletich RS, Bankiewicz KS, Quarantelli M, Plunkett RJ, Frank J, Kopin IJ, Di Chiro G. MRI detects acute degeneration of the nigrostriatal dopamine system after MPTP exposure in hemiparkinsonian monkeys. Annals of Neurology. 35: 689-97. PMID 8210225 DOI: 10.1002/ana.410350609  1
1994 Goldstein DS, Coronado L, Kopin IJ. 6-[Fluorine-18]fluorodopamine pharmacokinetics and dosimetry in humans. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 35: 964-73. PMID 8195883  1
1994 Viskupic E, Kvetnansky R, Sabban EL, Fukuhara K, Weise VK, Kopin IJ, Schwartz JP. Increase in rat adrenal phenylethanolamine N-methyltransferase mRNA level caused by immobilization stress depends on intact pituitary-adrenocortical axis. Journal of Neurochemistry. 63: 808-14. PMID 8051564  1
1994 Chang PC, Grossman E, Kopin IJ, Goldstein DS. On the existence of functional beta-adrenoceptors on vascular sympathetic nerve endings in the human forearm. Journal of Hypertension. 12: 681-90. PMID 7963493  1
1994 Yadid G, Pacak K, Kopin IJ, Goldstein DS. Endogenous serotonin stimulates striatal dopamine release in conscious rats. The Journal of Pharmacology and Experimental Therapeutics. 270: 1158-65. PMID 7932166  1
1994 Kopin IJ. Monoamine oxidase and catecholamine metabolism. Journal of Neural Transmission. Supplementum. 41: 57-67. PMID 7931266  1
1994 Finberg JP, Pacak K, Goldstein DS, Kopin IJ. Modification of cerebral cortical noradrenaline release by chronic inhibition of MAO-A. Journal of Neural Transmission. Supplementum. 41: 123-5. PMID 7931217  1
1994 Nankova B, Kvetnanský R, McMahon A, Viskupic E, Hiremagalur B, Frankle G, Fukuhara K, Kopin IJ, Sabban EL. Induction of tyrosine hydroxylase gene expression by a nonneuronal nonpituitary-mediated mechanism in immobilization stress. Proceedings of the National Academy of Sciences of the United States of America. 91: 5937-41. PMID 7912437 DOI: 10.1073/pnas.91.13.5937  1
1994 Eisenhofer G, Pecorella W, Pacak K, Hooper D, Kopin IJ, Goldstein DS. The neuronal and extraneuronal origins of plasma 3-methoxy-4-hydroxyphenylglycol in rats. Journal of the Autonomic Nervous System. 50: 93-107. PMID 7844319 DOI: 10.1016/0165-1838(94)90127-9  1
1993 Goldstein DS, Garty M, Bagdy G, Szemeredi K, Sternberg EM, Listwak S, Pacak K, Deka-Starosta A, Hoffman A, Chang PC. Role of CRH in glucopenia-induced adrenomedullary activation in rats. Journal of Neuroendocrinology. 5: 475-86. PMID 8680414 DOI: 10.1111/j.1365-2826.1993.tb00511.x  1
1993 Wolfovitz E, Grossman E, Folio CJ, Keiser HR, Kopin IJ, Goldstein DS. Derivation of urinary dopamine from plasma dihydroxyphenylalanine in humans. Clinical Science (London, England : 1979). 84: 549-57. PMID 8504632  1
1993 Kopin IJ. The pharmacology of Parkinson's disease therapy: an update. Annual Review of Pharmacology and Toxicology. 33: 467-95. PMID 8494348 DOI: 10.1146/annurev.pa.33.040193.002343  1
1993 Kopin IJ, Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Oldfield EH. Tissue implants in treatment of parkinsonian syndromes in animals and implications for use of tissue implants in humans. Advances in Neurology. 60: 707-14. PMID 8420215  1
1993 Lenders JW, Eisenhofer G, Armando I, Keiser HR, Goldstein DS, Kopin IJ. Determination of metanephrines in plasma by liquid chromatography with electrochemical detection. Clinical Chemistry. 39: 97-103. PMID 8419068  1
1993 Pacák K, Yadid G, Jakab G, Lenders JW, Kopin IJ, Goldstein DS. In vivo hypothalamic release and synthesis of catecholamines in spontaneously hypertensive rats. Hypertension. 22: 467-78. PMID 8406651  1
1993 Sheng JG, McShane LM, Plunkett RJ, Cummins AC, Oldfield EH, Kopin IJ, Palmatier MA. Dopaminergic neuronal sprouting and behavioral recovery in hemi-parkinsonian rats after implantation of amnion cells. Experimental Neurology. 123: 192-203. PMID 8405285 DOI: 10.1006/exnr.1993.1152  1
1993 Kopin IJ. Parkinson's disease: past, present, and future. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 9: 1-12. PMID 8397719 DOI: 10.1038/npp.1993.39  1
1993 Kvetnanský R, Fukuhara K, Pacák K, Cizza G, Goldstein DS, Kopin IJ. Endogenous glucocorticoids restrain catecholamine synthesis and release at rest and during immobilization stress in rats. Endocrinology. 133: 1411-9. PMID 8396019 DOI: 10.1210/endo.133.3.8396019  1
1993 Pacák K, Kvetnanský R, Palkovits M, Fukuhara K, Yadid G, Kopin IJ, Goldstein DS. Adrenalectomy augments in vivo release of norepinephrine in the paraventricular nucleus during immobilization stress. Endocrinology. 133: 1404-10. PMID 8396018 DOI: 10.1210/endo.133.3.8396018  1
1993 Finberg JP, Pacak K, Kopin IJ, Goldstein DS. Chronic inhibition of monoamine oxidase type A increases noradrenaline release in rat frontal cortex. Naunyn-Schmiedeberg's Archives of Pharmacology. 347: 500-5. PMID 8391652 DOI: 10.1007/BF00166742  1
1993 Pacák K, Palkovits M, Kvetnanský R, Fukuhara K, Armando I, Kopin IJ, Goldstein DS. Effects of single or repeated immobilization on release of norepinephrine and its metabolites in the central nucleus of the amygdala in conscious rats. Neuroendocrinology. 57: 626-33. PMID 8367029 DOI: 10.1159/000126417  1
1993 Nankova B, Devlin D, Kvetnanský R, Kopin IJ, Sabban EL. Repeated immobilization stress increases the binding of c-Fos-like proteins to a rat dopamine beta-hydroxylase promoter enhancer sequence. Journal of Neurochemistry. 61: 776-9. PMID 8336155  1
1993 Lenders JW, Kvetnansky R, Pacak K, Goldstein DS, Kopin IJ, Eisenhofer G. Extraneuronal metabolism of endogenous and exogenous norepinephrine and epinephrine in rats. The Journal of Pharmacology and Experimental Therapeutics. 266: 288-93. PMID 8331563  1
1993 Miletich RS, Comi G, Bankiewicz K, Plunkett R, Adams R, Di Chiro G, Kopin IJ. 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism and positron emission tomography after catechol-O-methyltransferase inhibition in normal and hemiparkinsonian monkeys. Brain Research. 626: 1-13. PMID 8281420 DOI: 10.1016/0006-8993(93)90556-3  1
1993 Pacák K, Palkovits M, Kvetnansky R, Kopin IJ, Goldstein DS. Stress-induced norepinephrine release in the paraventricular nucleus of rats with brainstem hemisections: a microdialysis study. Neuroendocrinology. 58: 196-201. PMID 8264865 DOI: 10.1159/000126533  1
1993 Goldstein DS, Eisenhofer G, Dunn BB, Armando I, Lenders J, Grossman E, Holmes C, Kirk KL, Bacharach S, Adams R, Herscovitch P, Kopin IJ. Positron emission tomographic imaging of cardiac sympathetic Innervation using 6-[18F]Fluorodopamine: Initial findings in humans Journal of the American College of Cardiology. 22: 1961-1971. PMID 8245356 DOI: 10.1016/0735-1097(93)90786-Z  1
1993 Yadid G, Pacak K, Golomb E, Harvey-White JD, Lieberman DM, Kopin IJ, Goldstein DS. Glycine stimulates striatal dopamine release in conscious rats. British Journal of Pharmacology. 110: 50-3. PMID 8220914  1
1993 Yadid G, Pacak K, Kopin IJ, Goldstein DS. Modified microdialysis probe for sampling extracellular fluid and administering drugs in vivo. The American Journal of Physiology. 265: R1205-11. PMID 7902019  1
1993 Kopin IJ. Monoamine oxidase (MAO): Relationships to foods, poisons and medicines Biogenic Amines. 9: 355-365.  1
1992 Kopin IJ. Features of the dopaminergic neurotoxin MPTP. Annals of the New York Academy of Sciences. 648: 96-104. PMID 1637076  1
1992 Kvetnansky R, Armando I, Weise VK, Holmes C, Fukuhara K, Deka-Starosta A, Kopin IJ, Goldstein DS. Plasma dopa responses during stress: dependence on sympathoneural activity and tyrosine hydroxylation. The Journal of Pharmacology and Experimental Therapeutics. 261: 899-909. PMID 1602395  1
1992 Kopin IJ. Origins and significance of dopa and catecholamine metabolites in body fluids. Pharmacopsychiatry. 25: 33-6. PMID 1579604 DOI: 10.1055/s-2007-1014384  1
1992 Kvetnanský R, Goldstein DS, Weise VK, Holmes C, Szemeredi K, Bagdy G, Kopin IJ. Effects of handling or immobilization on plasma levels of 3,4-dihydroxyphenylalanine, catecholamines, and metabolites in rats. Journal of Neurochemistry. 58: 2296-302. PMID 1573408  1
1992 Duncan MW, Marini AM, Watters R, Kopin IJ, Markey SP. Zinc, a neurotoxin to cultured neurons, contaminates cycad flour prepared by traditional guamanian methods. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 1523-37. PMID 1556606  1
1992 Marini AM, Lipsky RH, Schwartz JP, Kopin IJ. Accumulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in cultured cerebellar astrocytes. Journal of Neurochemistry. 58: 1250-8. PMID 1548462  1
1992 Duncan MW, Markey SP, Weick BG, Pearson PG, Ziffer H, Hu Y, Kopin IJ. 2-Amino-3-(methylamino)propanoic acid (BMAA) bioavailability in the primate. Neurobiology of Aging. 13: 333-7. PMID 1522948 DOI: 10.1016/0197-4580(92)90047-2  1
1992 Pacak K, Armando I, Komoly S, Fukuhara K, Weise VK, Holmes C, Kopin IJ, Goldstein DS. Hypercortisolemia inhibits yohimbine-induced release of norepinephrine in the posterolateral hypothalamus of conscious rats. Endocrinology. 131: 1369-76. PMID 1505468 DOI: 10.1210/endo.131.3.1505468  1
1992 Pacak K, Armando I, Fukuhara K, Kvetnansky R, Palkovits M, Kopin IJ, Goldstein DS. Noradrenergic activation in the paraventricular nucleus during acute and chronic immobilization stress in rats: an in vivo microdialysis study. Brain Research. 589: 91-6. PMID 1422825 DOI: 10.1016/0006-8993(92)91165-B  1
1992 McMahon A, Kvetnanský R, Fukuhara K, Weise VK, Kopin IJ, Sabban EL. Regulation of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA levels in rat adrenals by a single and repeated immobilization stress. Journal of Neurochemistry. 58: 2124-30. PMID 1349344  1
1992 Grossman E, Hoffman A, Armando I, Abassi Z, Kopin IJ, Goldstein DS. Sympathoadrenal contribution to plasma dopa (3,4-dihydroxyphenylalanine) in rats. Clinical Science (London, England : 1979). 83: 65-74. PMID 1325324  1
1991 Zuddas A, Corsini GU, Barker JL, Kopin IJ, Di Porzio U. Specific Reinnervation of Lesioned Mouse Striatum by Grafted Mesencephalic Dopaminergic Neurons. The European Journal of Neuroscience. 3: 72-85. PMID 12106271  1
1991 Duncan MW, Villacreses NE, Pearson PG, Wyatt L, Rapoport SI, Kopin IJ, Markey SP, Smith QR. 2-amino-3-(methylamino)-propanoic acid (BMAA) pharmacokinetics and blood-brain barrier permeability in the rat. The Journal of Pharmacology and Experimental Therapeutics. 258: 27-35. PMID 2072299  1
1991 Szemeredi K, Komoly S, Kopin IJ, Bagdy G, Keiser HR, Goldstein DS. Simultaneous measurement of plasma and brain extracellular fluid concentrations of catechols after yohimbine administration in rats. Brain Research. 542: 8-14. PMID 2054662 DOI: 10.1016/0006-8993(91)90990-D  1
1991 Grossman E, Chang PC, Hoffman A, Tamrat M, Kopin IJ, Goldstein DS. Tracer norepinephrine kinetics: dependence on regional blood flow and the site of infusion. The American Journal of Physiology. 260: R946-52. PMID 2035707  1
1991 Bankiewicz KS, Oldfield EH, Plunkett RJ, Schuette WH, Cogan DG, Hogan N, Zuddas A, Kopin IJ. Apparent unilateral visual neglect in MPTP-hemiparkinsonian monkeys is due to delayed initiation of motion. Brain Research. 541: 98-102. PMID 2029630 DOI: 10.1016/0006-8993(91)91080-K  1
1991 Palombo E, Porrino LJ, Crane AM, Bankiewicz KS, Kopin IJ, Sokoloff L. Cerebral metabolic effects of monoamine oxidase inhibition in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine acutely treated monkeys. Journal of Neurochemistry. 56: 1639-46. PMID 2013759  1
1991 Goldstein DS, Chang PC, Smith CB, Herscovitch P, Austin SM, Eisenhofer G, Kopin IJ. Dosimetric estimates for clinical positron emission tomographic scanning after injection of [18F]-6-fluorodopamine. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 32: 102-10. PMID 1988612  1
1991 Eisenhofer G, Esler MD, Goldstein DS, Kopin IJ. Neuronal uptake, metabolism, and release of tritium-labeled norepinephrine during assessment of its plasma kinetics. The American Journal of Physiology. 261: E505-15. PMID 1928342  1
1991 Szemeredi K, Pacak K, Kopin IJ, Goldstein DS. Sympathoneural and skeletal muscle contributions to plasma dopa responses in pithed rats. Journal of the Autonomic Nervous System. 35: 169-74. PMID 1744376 DOI: 10.1016/0165-1838(91)90094-J  1
1991 Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Kopin IJ, Oldfield EH. Fetal nondopaminergic neural implants in parkinsonian primates. Histochemical and behavioral studies. Journal of Neurosurgery. 74: 97-104. PMID 1670609 DOI: 10.3171/jns.1991.74.1.0097  1
1991 Culman J, Kopin IJ, Saavedra JM. Regulation of corticotropin-releasing hormone and pituitary-adrenocortical response during acute and repeated stress in the rat. Endocrine Regulations. 25: 151-8. PMID 1662551  1
1991 Goldstein DS, Grossman E, Tamrat M, Chang PC, Eisenhofer G, Bacher J, Kirk KL, Bacharach S, Kopin IJ. Positron emission imaging of cardiac sympathetic innervation and function using 18F-6-fluorodopamine: effects of chemical sympathectomy by 6-hydroxydopamine. Journal of Hypertension. 9: 417-23. PMID 1649861  1
1990 Goldstein DS, Chang PC, Eisenhofer G, Miletich R, Finn R, Bacher J, Kirk KL, Bacharach S, Kopin IJ. Positron emission tomographic imaging of cardiac sympathetic innervation and function. Circulation. 81: 1606-21. PMID 2331769  1
1990 Duncan MW, Steele JC, Kopin IJ, Markey SP. 2-Amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: an unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam. Neurology. 40: 767-72. PMID 2330104  1
1990 Palombo E, Porrino LJ, Bankiewicz KS, Crane AM, Sokoloff L, Kopin IJ. Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 860-9. PMID 2319306  1
1990 Bankiewicz KS, Plunkett RJ, Jacobowitz DM, Porrino L, di Porzio U, London WT, Kopin IJ, Oldfield EH. The effect of fetal mesencephalon implants on primate MPTP-induced parkinsonism. Histochemical and behavioral studies. Journal of Neurosurgery. 72: 231-44. PMID 2295921 DOI: 10.3171/jns.1990.72.2.0231  1
1990 Hovevey-Sion D, Eisenhofer G, Kopin IJ, Kirk KL, Chang PC, Szemeredi K, Goldstein DS. Metabolic fate of injected radiolabelled dopamine and 2-fluorodopamine in rats. Neuropharmacology. 29: 881-7. PMID 2255383 DOI: 10.1016/0028-3908(90)90137-G  1
1990 Chang PC, Szemeredi K, Grossman E, Kopin IJ, Goldstein DS. Fate of tritiated 6-fluorodopamine in rats: a false neurotransmitter for positron emission tomographic imaging of sympathetic innervation and function. The Journal of Pharmacology and Experimental Therapeutics. 255: 809-17. PMID 2243352  1
1990 Garty M, Deka-Starosta A, Chang P, Kopin IJ, Goldstein DS. Effects of clonidine on renal sympathetic nerve activity and norepinephrine spillover. The Journal of Pharmacology and Experimental Therapeutics. 254: 1068-75. PMID 2168483  1
1990 Kopin IJ. In-vivo quantitative imaging of catecholaminergic nerve terminals in brain and peripheral organs using positron emission tomography (PET). Journal of Neural Transmission. Supplementum. 32: 19-27. PMID 2089090  1
1990 Kopin IJ. False adrenergic transmitters and positron emission tomographic imaging of myocardial sympathetic innervation. Circulation. 82: 646-8. PMID 1973639  1
1990 Bankiewicz KS, Plunkett RJ, Mefford I, Kopin IJ, Oldfield EH. Behavioral recovery from MPTP-induced parkinsonism in monkeys after intracerebral tissue implants is not related to CSF concentrations of dopamine metabolites. Progress in Brain Research. 82: 561-71. PMID 1705356  1
1990 Garty M, Deka-Starosta A, Stull R, Kopin IJ, Goldstein DS. Effects of general anesthetics on plasma levels of catechols in intact and in adrenal-demedullated rats Biogenic Amines. 7: 435-443.  1
1990 Szemeredi K, Bagdy G, Stull R, Kopin IJ, Goldstein DS. Cortisol and alpha-2 adrenergic regulation of sympathoneural activity Biogenic Amines. 7: 445-454.  1
1989 Eisenhofer G, Goldstein DS, Kopin IJ. Plasma dihydroxyphenylglycol for estimation of noradrenaline neuronal re-uptake in the sympathetic nervous system in vivo. Clinical Science (London, England : 1979). 76: 171-82. PMID 2924508  1
1989 Zuddas A, Corsini GU, Schinelli S, Barker JL, Kopin IJ, di Porzio U. Acetaldehyde directly enhances MPP+ neurotoxicity and delays its elimination from the striatum. Brain Research. 501: 11-22. PMID 2804689 DOI: 10.1016/0006-8993(89)91021-4  1
1989 Garty M, Stull R, Kopin IJ, Goldstein DS. Skin color, aging, and plasma L-dopa levels. Journal of the Autonomic Nervous System. 26: 261-3. PMID 2754181 DOI: 10.1016/0165-1838(89)90175-6  1
1989 Deka-Starosta A, Garty M, Zukowska-Grojec Z, Keiser HR, Kopin IJ, Goldstein DS. Renal sympathetic nerve activity and norepinephrine release in rats. The American Journal of Physiology. 257: R229-36. PMID 2750962  1
1989 Goldstein DS, Eisenhofer G, Garty M, Sax FL, Keiser HR, Kopin IJ. Pharmacologic and tracer methods to study sympathetic function in primary hypertension. Clinical and Experimental Hypertension. Part a, Theory and Practice. 11: 173-89. PMID 2743589 DOI: 10.3109/10641968909045422  1
1989 Garty M, Deka-Starosta A, Stull R, Kopin IJ, Goldstein DS. Plasma levels of catechols after fasting in intact or adrenal-demedullated rats. Journal of the Autonomic Nervous System. 26: 181-4. PMID 2723338 DOI: 10.1016/0165-1838(89)90167-7  1
1989 Szemeredi K, Stull R, Kopin IJ, Goldstein DS. Effects of a peripherally acting alpha 2-adrenoceptor antagonist (L-659,066) on hemodynamics and plasma levels of catechols in conscious rats. European Journal of Pharmacology. 170: 53-9. PMID 2575527 DOI: 10.1016/0014-2999(89)90133-7  1
1989 Zuddas A, Corsini GU, Schinelli S, Johannessen JN, di Porzio U, Kopin IJ. MPTP treatment combined with ethanol or acetaldehyde selectively destroys dopaminergic neurons in mouse substantia nigra. Brain Research. 501: 1-10. PMID 2572305 DOI: 10.1016/0006-8993(89)91020-2  1
1989 Marini AM, Schwartz JP, Kopin IJ. The neurotoxicity of 1-methyl-4-phenylpyridinium in cultured cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3665-72. PMID 2571685  1
1989 Johannessen JN, Chiueh CC, Bacon JP, Garrick NA, Burns RS, Weise VK, Kopin IJ, Parisi JE, Markey SP. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the dog: effect of pargyline pretreatment. Journal of Neurochemistry. 53: 582-9. PMID 2568405  1
1989 Szemeredi K, Zukowska-Grojec Z, Bagdy G, Fekete MI, Kopin IJ. Opposite effects of chronic cortisol treatment on pre- and postsynaptic actions of clonidine in pithed rats. Journal of Autonomic Pharmacology. 9: 35-43. PMID 2566614  1
1989 Eisenhofer G, Brush JE, Cannon RO, Stull R, Kopin IJ, Goldstein DS. Plasma dihydroxyphenylalanine and total body and regional noradrenergic activity in humans. The Journal of Clinical Endocrinology and Metabolism. 68: 247-55. PMID 2563731 DOI: 10.1210/jcem-68-2-247  1
1989 Eisenhofer G, Hovevey-Sion D, Kopin IJ, Miletich R, Kirk KL, Finn R, Goldstein DS. Neuronal uptake and metabolism of 2- and 6-fluorodopamine: false neurotransmitters for positron emission tomographic imaging of sympathetically innervated tissues. The Journal of Pharmacology and Experimental Therapeutics. 248: 419-27. PMID 2563292  1
1989 Goldstein DS, Polinsky RJ, Garty M, Robertson D, Brown RT, Biaggioni I, Stull R, Kopin IJ. Patterns of plasma levels of catechols in neurogenic orthostatic hypotension. Annals of Neurology. 26: 558-63. PMID 2510587 DOI: 10.1002/ana.410260410  1
1989 Hovevey-Sion D, Kopin IJ, Stull RW, Goldstein DS. Effects of monoamine oxidase inhibitors on levels of catechols and homovanillic acid in striatum and plasma. Neuropharmacology. 28: 791-7. PMID 2506486 DOI: 10.1016/0028-3908(89)90169-X  1
1989 Garty M, Deka-Starosta A, Chang PC, Eisenhofer G, Zukowska-Grojec Z, Stull R, Kopin IJ, Goldstein DS. Plasma levels of catechols during reflexive changes in sympathetic nerve activity. Neurochemical Research. 14: 523-31. PMID 2503766 DOI: 10.1007/BF00964913  1
1989 Goldstein DS, Eisenhofer G, Garty M, Folio CJ, Stull R, Brush JE, Sax FL, Keiser HR, Kopin IJ. Implications of plasma levels of catechols in the evaluation of sympathoadrenomedullary function. American Journal of Hypertension. 2: 133S-139S. PMID 2493793  1
1989 Duncan MW, Kopin IJ, Crowley JS, Jones SM, Markey SP. Quantification of the putative neurotoxin 2-amino-3-(methylamino)propanoic acid (BMAA) in cycadales: analysis of the seeds of some members of the family Cycadaceae. Journal of Analytical Toxicology. 13: suppl A-G. PMID 2490746  1
1988 Kopin IJ, Oliver JA, Polinsky RJ. Relationship between urinary excretion of homovanillic acid and norepinephrine metabolites in normal subjects and patients with orthostatic hypotension. Life Sciences. 43: 125-31. PMID 3393060 DOI: 10.1016/0024-3205(88)90289-5  1
1988 Hovevey-Sion D, Harvey-White J, Kopin IJ, Goldstein DS. Measurement of homovanillic acid in small volumes of plasma using liquid chromatography with electrochemical detection. Journal of Chromatography. 426: 141-7. PMID 3384866 DOI: 10.1016/S0378-4347(00)81935-0  1
1988 Eisenhofer G, Ropchak TG, Kopin IJ, Goldstein DS. Release, metabolism and intraneuronal disposition of exogenous, endogenous and newly synthesized norepinephrine in the rat vas deferens. The Journal of Pharmacology and Experimental Therapeutics. 245: 81-8. PMID 3361453  1
1988 Szemeredi K, Zukowska-Grojec Z, Bagdy G, Hill J, Kopin IJ. Evidence for a direct peripheral effect of clonidine on the norepinephrine release in vivo in pithed rats. European Journal of Pharmacology. 145: 251-5. PMID 3350046 DOI: 10.1016/0014-2999(88)90426-8  1
1988 Goldstein DS, Eisenhofer G, Stull R, Folio CJ, Keiser HR, Kopin IJ. Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans. The Journal of Clinical Investigation. 81: 213-20. PMID 3335637 DOI: 10.1172/JCI113298  1
1988 Polinsky RJ, Taylor IL, Weise V, Kopin IJ. Gastrin responses in patients with adrenergic insufficiency. Journal of Neurology, Neurosurgery, and Psychiatry. 51: 67-71. PMID 3280734  1
1988 Kopin IJ, Bankiewicz KS, Harvey-White J. Assessment of brain dopamine metabolism from plasma HVA and MHPG during debrisoquin treatment: validation in monkeys treated with MPTP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 1: 119-25. PMID 3266957  1
1988 Palombo E, Porrino LJ, Bankiewicz KS, Crane AM, Kopin IJ, Sokoloff L. Administration of MPTP acutely increases glucose utilization in the substantia nigra of primates. Brain Research. 453: 227-34. PMID 3261197 DOI: 10.1016/0006-8993(88)90162-X  1
1988 Kopin IJ, Bankiewicz K, Harvey-White J. Effect of MPTP-induced parkinsonism in monkeys on the urinary excretion of HVA and MHPG during debrisoquin administration. Life Sciences. 43: 133-41. PMID 3260652 DOI: 10.1016/0024-3205(88)90290-1  1
1988 Schinelli S, Zuddas A, Kopin IJ, Barker JL, di Porzio U. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon. Journal of Neurochemistry. 50: 1900-7. PMID 3259619  1
1988 Ho VW, Porrino LJ, Crane AM, Burns RS, Kopin IJ, Sokoloff L. Metabolic mapping of the oculomotor system in MPTP-induced parkinsonian monkeys. Annals of Neurology. 23: 86-9. PMID 3257855 DOI: 10.1002/ana.410230114  1
1988 Bankiewicz KS, Plunkett RJ, Kophin IJ, Jacobowitz DM, London WT, Oldfield EH. Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts. Progress in Brain Research. 78: 543-9. PMID 3247447  1
1988 Eisenhofer G, Kirk KL, Kopin IJ, Goldstein DS. Simultaneous determination of endogenous catechols and exogenous 2- and 6-fluorinated catechols in tissue and plasma using liquid chromatography with electrochemical detection. Journal of Chromatography. 431: 156-62. PMID 3235527 DOI: 10.1016/S0378-4347(00)83079-0  1
1988 Eisenhofer G, Goldstein DS, Ropchak TG, Nguyen HQ, Keiser HR, Kopin IJ. Source and physiological significance of plasma 3,4-dihydroxyphenylglycol and 3-methoxy-4-hydroxyphenylglycol. Journal of the Autonomic Nervous System. 24: 1-14. PMID 3209794 DOI: 10.1016/0165-1838(88)90130-0  1
1988 Szemeredi K, Bagdy G, Stull R, Keiser HR, Kopin IJ, Goldstein DS. Sympathoadrenomedullary hyper-responsiveness to yohimbine in juvenile spontaneously hypertensive rats. Life Sciences. 43: 1063-8. PMID 3172973 DOI: 10.1016/0024-3205(88)90201-9  1
1988 Szemeredi K, Bagdy G, Stull R, Calogero AE, Kopin IJ, Goldstein DS. Sympathoadrenomedullary inhibition by chronic glucocorticoid treatment in conscious rats. Endocrinology. 123: 2585-90. PMID 3168935 DOI: 10.1210/endo-123-5-2585  1
1988 Kopin IJ, Markey SP. MPTP toxicity: implications for research in Parkinson's disease. Annual Review of Neuroscience. 11: 81-96. PMID 3129982 DOI: 10.1146/annurev.ne.11.030188.000501  1
1988 Kopin IJ, Schoenberg DG. MPTP in animal models of Parkinson's disease. The Mount Sinai Journal of Medicine, New York. 55: 43-9. PMID 3126391  1
1988 Kopin IJ, Eisenhofer G, Goldstein D. Sympathoadrenal medullary system and stress. Advances in Experimental Medicine and Biology. 245: 11-23. PMID 3067552  1
1988 Kopin IJ. MPTP effects on dopamine neurons. Annals of the New York Academy of Sciences. 537: 451-61. PMID 3059935  1
1988 Kopin IJ, White JH, Bankiewicz K. A new approach to biochemical evaluation of brain dopamine metabolism. Cellular and Molecular Neurobiology. 8: 171-9. PMID 3044592 DOI: 10.1007/BF00711243  1
1988 Eisenhofer G, Goldstein DS, Ropchak TG, Kopin IJ. Source and physiological significance of plasma 3,4-dihydroxyphenylalanine in the rat. Journal of Neurochemistry. 51: 1204-13. PMID 2901461  1
1988 Polinsky RJ, Brown RT, Burns RS, Harvey-White J, Kopin IJ. Low lumbar CSF levels of homovanillic acid and 5-hydroxyindoleacetic acid in multiple system atrophy with autonomic failure. Journal of Neurology, Neurosurgery, and Psychiatry. 51: 914-9. PMID 2462617  0.52
1988 Zuddas A, Porzio UD, Kopin IJ, Corsini GU. Ethanol and acetaldehyde enhance MPTP neurotoxicity by interfering with both MPP+ pharmacokinetics and pharmacodynamics: In vivo and in vitro studies Pharmacological Research Communications. 20: 407. DOI: 10.1016/S0031-6989(88)80537-X  1
1988 Kopin IJ, Lake CR. Question the experts Journal of Clinical Psychopharmacology. 8: 305-306.  1
1987 Eisenhofer G, Ropchak TG, Stull RW, Goldstein DS, Keiser HR, Kopin IJ. Dihydroxyphenylglycol and intraneuronal metabolism of endogenous and exogenous norepinephrine in the rat vas deferens. The Journal of Pharmacology and Experimental Therapeutics. 241: 547-53. PMID 3572811  1
1987 Porrino LJ, Burns RS, Crane AM, Palombo E, Kopin IJ, Sokoloff L. Local cerebral metabolic effects of L-dopa therapy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in monkeys. Proceedings of the National Academy of Sciences of the United States of America. 84: 5995-9. PMID 3497401  1
1987 Porrino LJ, Burns RS, Crane AM, Palombo E, Kopin IJ, Sokoloff L. Changes in local cerebral glucose utilization associated with Parkinson's syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the primate. Life Sciences. 40: 1657-64. PMID 3494179 DOI: 10.1016/0024-3205(87)90014-2  1
1987 Kopin IJ. MPTP: an industrial chemical and contaminant of illicit narcotics stimulates a new era in research on Parkinson's disease. Environmental Health Perspectives. 75: 45-51. PMID 3319563  1
1987 Barone P, Bankiewicz KS, Corsini GU, Kopin IJ, Chase TN. Dopaminergic mechanisms in hemiparkinsonian monkeys. Neurology. 37: 1592-5. PMID 3309720  0.64
1987 Schuette WH, Bankiewicz KS, Markowitz A, Plowman FA, Kopin IJ. A system for measuring the angular response of hemiparkinsonian monkeys to a food stimulus. Medical Instrumentation. 21: 314-6. PMID 3123898  1
1987 Chiueh CC, Firnau G, Burns RS, Nahmias C, Chirakal R, Kopin IJ, Garnett ES. Determination and visualization of damage to striatal dopaminergic terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by [18F]-labeled 6-fluoro-L-dopa and positron emission tomography. Advances in Neurology. 45: 167-9. PMID 3103385  1
1987 Goldstein DS, Eisenhofer G, Sax FL, Keiser HR, Kopin IJ. Plasma norepinephrine pharmacokinetics during mental challenge. Psychosomatic Medicine. 49: 591-605. PMID 2827219  1
1987 Eisenhofer G, Goldstein DS, Stull RW, Gold PW, Keiser HR, Kopin IJ. Dissociation between corticotrophin and catecholamine responses to isoprenaline in humans. Clinical and Experimental Pharmacology & Physiology. 14: 337-41. PMID 2822312  1
1987 Schinelli S, Corona GL, Kopin IJ. Mechanism of MPTP toxicity in neural primary cultures Pharmacological Research Communications. 19: 947-948.  1
1986 Siever LJ, Uhde TW, Jimerson DC, Lake CR, Kopin IJ, Murphy DL. Indices of noradrenergic output in depression. Psychiatry Research. 19: 59-73. PMID 3786600  0.48
1986 Bankiewicz KS, Oldfield EH, Chiueh CC, Doppman JL, Jacobowitz DM, Kopin IJ. Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Life Sciences. 39: 7-16. PMID 3487691  0.6
1986 Joyce JN, Marshall JF, Bankiewicz KS, Kopin IJ, Jacobowitz DM. Hemiparkinsonism in a monkey after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is associated with regional ipsilateral changes in striatal dopamine D-2 receptor density. Brain Research. 382: 360-4. PMID 2944565 DOI: 10.1016/0006-8993(86)91345-4  1
1985 Weise VK, Palkovits M, Kopin IJ. Effect of ventral noradrenergic bundle transection and locus coeruleus lesions on urinary 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) excretion in the rat. Brain Research. 359: 239-45. PMID 4075147  0.48
1985 Zukowska-Grojec Z, Zerbe RL, Jimerson DC, Bayorh MA, Palkovits M, Kopin IJ. Catecholaminergic activity of the baroreceptor areas of the brain in response to bilateral dorsolateral transection of medulla oblongata in rats. Brain Research. 325: 231-40. PMID 3978417  0.48
1985 Chiueh CC, Burns RS, Markey SP, Jacobowitz DM, Kopin IJ. Primate model of parkinsonism: selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys. Life Sciences. 36: 213-8. PMID 3871241 DOI: 10.1016/0024-3205(85)90061-X  1
1985 Torda T, Kopin IJ. Lack of preventive effect of 6-hydroxy-dopamine on a decrease of beta-adrenergic receptors induced by repeated stress in the heart of rats. Endocrinologia Experimentalis. 19: 47-51. PMID 2985356  0.44
1985 Burns RS, LeWitt PA, Ebert MH, Pakkenberg H, Kopin IJ. The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The New England Journal of Medicine. 312: 1418-21. PMID 2581135 DOI: 10.1056/NEJM198505303122203  0.52
1984 Polinsky RJ, Jimerson DC, Kopin IJ. Chronic autonomic failure: CSF and plasma 3-methoxy-4-hydroxyphenylglycol. Neurology. 34: 979-83. PMID 6539879  0.48
1984 Zavadil AP, Ross RJ, Calil HM, Linnoila M, Blombery P, Jimerson DC, Kopin IJ, Potter WZ. The effect of desmethylimipramine on the metabolism of norepinephrine. Life Sciences. 35: 1061-8. PMID 6482645  0.48
1984 Kopin IJ, Blombery P, Ebert MH, Gordon EK, Jimerson DC, Markey SP, Polinsky RJ. Disposition and metabolism of MHPG-CD3 in humans: plasma MHPG as the principal pathway of norepinephrine metabolism and as an important determinant of CSF levels of MHPG. Advances in Biochemical Psychopharmacology. 39: 57-68. PMID 6464833  1
1984 Martin PR, Ebert MH, Gordon EK, Weingartner H, Kopin IJ. Catecholamine metabolism during clonidine withdrawal. Psychopharmacology. 84: 58-63. PMID 6436892  0.8
1984 Kopin IJ, Jimerson DC, Markey SP, Ebert MH, Polinsky RJ. Disposition and metabolism of MHPG in humans: application to studies in depression. Pharmacopsychiatry. 17: 3-8. PMID 6369349 DOI: 10.1055/s-2007-1017399  1
1984 Chiueh CC, Markey SP, Burns RS, Johannessen JN, Jacobowitz DM, Kopin IJ. Neurochemical and behavioral effects of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) in rat, guinea pig, and monkey. Psychopharmacology Bulletin. 20: 548-53. PMID 6332333  1
1984 Jacobowitz DM, Burns RS, Chiueh CC, Kopin IJ. N-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP) causes destruction of the nigrostriatal but not the mesolimbic dopamine system in the monkey. Psychopharmacology Bulletin. 20: 416-22. PMID 6332329  0.52
1984 Pfeiffer A, Pfeiffer DG, Feuerstein G, Faden AI, Kopin IJ. An increase in opiate receptor-sites is associated with enhanced cardiovascular depressant, but not respiratory depressant action of morphine. Brain Research. 296: 305-11. PMID 6322927 DOI: 10.1016/0006-8993(84)90066-0  1
1984 Chiueh CC, Markey SP, Burns RS, Johannessen JN, Pert A, Kopin IJ. Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat. European Journal of Pharmacology. 100: 189-94. PMID 6203759 DOI: 10.1016/0014-2999(84)90221-8  1
1984 Martin PR, Weingartner H, Gordon EK, Burns RS, Linnoila M, Kopin IJ, Ebert MH. Central nervous system catecholamine metabolism in Korsakoff's psychosis. Annals of Neurology. 15: 184-7. PMID 6200058 DOI: 10.1002/ana.410150212  0.8
1984 Martin PR, Ebert MH, Gordon EK, Linnoila M, Kopin IJ. Effects of clonidine on central and peripheral catecholamine metabolism. Clinical Pharmacology and Therapeutics. 35: 322-7. PMID 6199153  0.8
1984 Zamir N, Skofitsch G, Bannon MJ, Helke CJ, Kopin IJ, Jacobowitz DM. Primate model of Parkinson's disease: alterations in multiple opioid systems in the basal ganglia. Brain Research. 322: 356-60. PMID 6150750 DOI: 10.1016/0006-8993(84)90133-1  1
1984 Kafka MS, Polinsky RJ, Williams A, Kopin IJ, Lake CR, Ebert MH, Tokola NS. Alpha-adrenergic receptors in orthostatic hypotension syndromes. Neurology. 34: 1121-5. PMID 6087206  0.48
1983 Kopin IJ, Gordon EK, Jimerson DC, Polinsky RJ. Relation between plasma and cerebrospinal fluid levels of 3-methoxy-4-hydroxyphenylglycol. Science (New York, N.Y.). 219: 73-5. PMID 6849119  0.8
1983 Goldstein DS, Lake CR, Chernow B, Ziegler MG, Coleman MD, Taylor AA, Mitchell JR, Kopin IJ, Keiser HR. Age-dependence of hypertensive-normotensive differences in plasma norepinephrine. Hypertension. 5: 100-4. PMID 6848457  0.48
1983 Martin PR, Ebert MH, Gordon EK, Kopin IJ. Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder. Clinical Pharmacology and Therapeutics. 33: 19-27. PMID 6848295  0.8
1983 Ross RJ, Zavadil AP, Calil HM, Linnoila M, Kitanaka I, Blombery P, Kopin IJ, Potter WZ. Effects of desmethylimipramine on plasma norepinephrine, pulse, and blood pressure. Clinical Pharmacology and Therapeutics. 33: 429-37. PMID 6831821  0.44
1983 Jimerson DC, Insel TR, Reus VI, Kopin IJ. Increased plasma MHPG in dexamethasone-resistant depressed patients. Archives of General Psychiatry. 40: 173-6. PMID 6824413  0.48
1983 Williford DJ, Zavadil AP, Walsh RA, Weise V, Kopin IJ, Gillis RA. Influence of vagotomy on changes in feline plasma catecholamine levels induced by occlusion of either the left or right coronary vessel. Cardiovascular Research. 17: 568-76. PMID 6627277 DOI: 10.1093/cvrese/17.9.568  1
1983 Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proceedings of the National Academy of Sciences of the United States of America. 80: 4546-50. PMID 6192438  1
1983 Oertel WH, Graybiel AM, Mugnaini E, Elde RP, Schmechel DE, Kopin IJ. Coexistence of glutamic acid decarboxylase- and somatostatin-like immunoreactivity in neurons of the feline nucleus reticularis thalami. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 1322-32. PMID 6133922  1
1982 Lewy AJ, Wehr TA, Rosenthal NE, Nurnberger JI, Siever LJ, Uhde TW, Newsome DA, Becker LE, Markey SP, Kopin IJ, Goodwin FK. Melatonin secretion as a neurobiological "marker" and effects of light in humans. Psychopharmacology Bulletin. 18: 127-9. PMID 7156273  1
1982 Oertel WH, Mugnaini E, Tappaz ML, Weise VK, Dahl AL, Schmechel DE, Kopin IJ. Central GABAergic innervation of neurointermediate pituitary lobe: biochemical and immunocytochemical study in the rat. Proceedings of the National Academy of Sciences of the United States of America. 79: 675-9. PMID 6952219 DOI: 10.1073/pnas.79.2.675  1
1982 Cohen RM, Campbell IC, Yamaguchi I, Pickar D, Kopin IJ, Murphy DL. Cardiovascular changes in response to selective monoamine oxidase inhibition in the rat. European Journal of Pharmacology. 80: 155-60. PMID 6284529 DOI: 10.1016/0014-2999(82)90193-5  1
1982 Linnoila M, Karoum F, Calil HM, Kopin IJ, Potter WZ. Alteration of norepinephrine metabolism with desipramine and zimelidine in depressed patients. Archives of General Psychiatry. 39: 1025-8. PMID 6214234  0.44
1981 Tetsuo M, Polinsky RJ, Markey SP, Kopin IJ. Urinary 6-hydroxymelatonin excretion in patients with orthostatic hypotension. The Journal of Clinical Endocrinology and Metabolism. 53: 607-10. PMID 7263843 DOI: 10.1210/jcem-53-3-607  1
1981 Jimerson DC, Ballenger JC, Lake CR, Post RM, Goodwin FK, Kopin IJ. Plasma and CSF MHPG in normals [proceedings]. Psychopharmacology Bulletin. 17: 86-7. PMID 7232666  0.48
1981 Jimerson DC, Nurnberger JI, Post RM, Gershon ES, Kopin IJ. Plasma MHPG in rapid cyclers and healthy twins. Archives of General Psychiatry. 38: 1287-90. PMID 7197905  0.48
1981 Torda T, Yamaguchi I, Hirata F, Kopin IJ, Axelrod J. Mepacrine treatment prevents immobilization-induced desensitization of beta-adrenergic receptors in rat hypothalamus and brain stem. Brain Research. 205: 441-4. PMID 6258719 DOI: 10.1016/0006-8993(81)90358-9  1
1981 Torda T, Yamaguchi I, Hirata F, Kopin IJ, Axelrod J. Quinacrine-blocked desensitization of adrenoceptors after immobilization stress or repeated injection of isoproterenol in rats. The Journal of Pharmacology and Experimental Therapeutics. 216: 334-8. PMID 6257888  1
1981 Helke CJ, DiMicco JA, Jacobowitz DM, Kopin IJ. Effect of capsaicin administration to neonatal rats on the substance P content of discrete CNS regions. Brain Research. 222: 428-31. PMID 6169396 DOI: 10.1016/0006-8993(81)91049-0  1
1980 Potter WZ, Zavadil AP, Kopin IJ, Goodwin FK. Single-dose kinetics predict steady-state concentrations on imipramine and desipramine. Archives of General Psychiatry. 37: 314-20. PMID 7362419  0.48
1980 Lewy AJ, Tetsuo M, Markey SP, Goodwin FK, Kopin IJ. Pinealectomy abolishes plasma melatonin in the rat. The Journal of Clinical Endocrinology and Metabolism. 50: 204-5. PMID 7350183 DOI: 10.1210/jcem-50-1-204  1
1976 Kopin IJ, Kaufman S, Viveros H, Jacobowitz D, Lake CR, Ziegler MG, Lovenberg W, Goodwin FK. NIH conference. Dopamine- -hydroxylase. Basic and clinical studies. Annals of Internal Medicine. 85: 211-23. PMID 782312  0.48
1976 Grobecker H, Saavedra JM, Roizen MF, Weise V, Kopin IJ, Axelrod J. Peripheral and central catecholaminergic neurons in genetic and experimental hypertension in rats. Clinical Science and Molecular Medicine. Supplement. 3: 377s-380s. PMID 15756  1
1975 Sattin A, Axelrod J, Kopin IJ, Nauta WJ. Ilya Glezer's Struggle. Science (New York, N.Y.). 187: 902. PMID 17745263 DOI: 10.1126/science.187.4180.902  1
1975 Thoa NB, Wooten GF, Axelrod J, Kopin IJ. On the mechanism of release of norepinephrine from sympathetic nerves induced by depolarizing agents and sympathomimetic drugs. Molecular Pharmacology. 11: 10-8. PMID 1117862  1
1975 Wooten GF, Kopin IJ, Axelrod J. Effects of colchicine and vinblastine on axonal transport and transmitter release in sympathetic nerves. Annals of the New York Academy of Sciences. 253: 528-34. PMID 50036  1
1973 Wooten GF, Thoa NB, Kopin IJ, Axelrod J. Enhanced release of dopamine -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline. Molecular Pharmacology. 9: 178-83. PMID 4351235  1
1972 Thoa NB, Wooten GF, Axelrod J, Kopin IJ. Inhibition of release of dopamine- -hydroxylase and norepinephrine from sympathetic nerves by colchicine, vinblastine, or cytochalasin-B (hypogastric nerve stimulation-exocytosis-microtubules-microfilaments-guinea pig). Proceedings of the National Academy of Sciences of the United States of America. 69: 520-2. PMID 4333989  1
1972 Silberstein SD, Lemberger L, Klein DC, Axelrod J, Kopin IJ. Induction of adrenal tyrosine hydroxylase in organ culture. Neuropharmacology. 11: 721-6. PMID 4151251 DOI: 10.1016/0028-3908(72)90081-0  1
1971 Johnson DG, Thoa NB, Weinshilboum R, Axelrod J, Kopin IJ. Enhanced release of dopamine- -hydroxylase from sympathetic nerves by calcium and phenoxybenzamine and its reversal by prostaglandins. Proceedings of the National Academy of Sciences of the United States of America. 68: 2227-30. PMID 5289380  1
1971 Davis JM, Kopin IJ, Lemberger L, Axelrod J. Effects of urinary pH on amphetamine metabolism. Annals of the New York Academy of Sciences. 179: 493-501. PMID 5285389  1
1971 Weinshilboum RM, Thoa NB, Johnson DG, Kopin IJ, Axelrod J. Proportional release of norepinephrine and dopamine- -hydroxylase from sympathetic nerves. Science (New York, N.Y.). 174: 1349-51. PMID 5135722  1
1971 Chase TN, Breese GR, Gordon EK, Kopin IJ. Catecholamine metabolism in the dog: comparison of intravenously and intraventricularly administered [14C]dopamine and [3H]norepinephrine. Journal of Neurochemistry. 18: 135-40. PMID 5107962  0.96
1971 Lemberger L, Tamarkin NR, Axelrod J, Kopin IJ. Delta-9-tetrahydrocannabinol: metabolism and disposition in long-term marihuana smokers. Science (New York, N.Y.). 173: 72-4. PMID 5087483  1
1971 Lemberger L, Axelrod J, Kopin IJ. Metabolism and disposition of delta-9-tetrahydrocannabinol in man. Pharmacological Reviews. 23: 371-80. PMID 4943951  1
1971 Weinshilboum RM, Kvetnansky R, Axelrod J, Kopin IJ. Elevation of serum dopamine-beta-hydroxylase activity with forced immobilization. Nature: New Biology. 230: 287-8. PMID 4930611  1
1971 Lemberger L, Axelrod J, Kopin IJ. The disposition and metabolism of tryptamine and the in vivo formation of 6-hydroxytryptamine in the rabbit. The Journal of Pharmacology and Experimental Therapeutics. 177: 169-76. PMID 4398046  1
1970 Lemberger L, Silberstein SD, Axelrod J, Kopin IJ. Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. Science (New York, N.Y.). 170: 1320-2. PMID 5479011  1
1970 Breese GR, Kopin IJ, Weise VK. Effects of amphetamine derivatives on brain dopamine and noradrenaline. British Journal of Pharmacology. 38: 537-45. PMID 4909707  0.96
1970 Breese GR, Chase TN, Kopin IJ. Effect of monoamine oxidase inhibitors on the disposition of intracisternally administered metaraminol-3H. Biochemical Pharmacology. 19: 525-32. PMID 4396250  0.96
1969 Schildkraut JJ, Schanberg SM, Breese GR, Kopin IJ. Effects of psychoactive drugs on the metabolism of intracisternally administered serotonin in rat brain. Biochemical Pharmacology. 18: 1971-8. PMID 5811629  1
1969 Breese GR, Chase TN, Kopin IJ. Metabolism of some phenylethylamines and their beta-hydroxylated analogs in brain. The Journal of Pharmacology and Experimental Therapeutics. 165: 9-13. PMID 5782838  0.96
1969 Axelrod J, Kopin IJ. The uptake, storage, release and metabolism of noradrenaline in sympathetic nerves. Progress in Brain Research. 31: 21-32. PMID 4900113 DOI: 10.1016/S0079-6123(08)63224-0  1
1969 Schildkraut JJ, Schanberg SM, Kopin IJ, Durell J. Affective disorders and norepinephrine pharmacology. International Psychiatry Clinics. 6: 83-141. PMID 4897536  1
1969 Breese GR, Chase TN, Kopin IJ. Metabolism of tyramine-3H and octopamine-3H by rat brain. Biochemical Pharmacology. 18: 863-9. PMID 4389230  0.96
1968 Schanberg SM, Schildkraut JJ, KrÄ­vánek J, Kopin IJ. Effect of cortical spreading depression on norepinephrine-H3 metabolism in brain stem. Experientia. 24: 909-10. PMID 5709032 DOI: 10.1007/BF02138647  1
1968 Kopin IJ, Breese GR, Krauss KR, Weise VK. Selective release of newly synthesized norepinephrine from the cat spleen during sympathetic nerve stimulation. The Journal of Pharmacology and Experimental Therapeutics. 161: 271-8. PMID 5650139  0.96
1968 Schanberg SM, Schildkraut JJ, Breese GR, Kopin IJ. Metabolism of normetanephrine-H3 in rat brain--identification of conjugated 3-methoxy-4-hydrophenylglycol as the major metabolite. Biochemical Pharmacology. 17: 247-54. PMID 5647052  1
1968 Schanberg SM, Breese GR, Schildkraut KK, Gordon EK, Kopin IJ. 3-methoxy-4-hydroxyphenylglycol sulfate in brain and cerebrospinal fluid. Biochemical Pharmacology. 17: 2006-8. PMID 4972145  1
1968 Chase TN, Breese GR, Carpenter DO, Schanberg SM, Kopin IJ. Stimulation-induced release of serotonin. Advances in Pharmacology. 6: 351-64. PMID 4298804 DOI: 10.1016/S1054-3589(08)61191-6  1
1967 Schanberg SM, Schildkraut JJ, Kopin IJ. The effects of pentobarbital on the fate of intracisternally administered norepinephrine-H3. The Journal of Pharmacology and Experimental Therapeutics. 157: 311-8. PMID 6039823  1
1967 Chase TN, Breese GR, Kopin IJ. Serotonin release from brain slices by electrical stimulation: regional differences and effect of LSD. Science (New York, N.Y.). 157: 1461-3. PMID 6037863  0.96
1967 Schanberg SM, Schildkraut JJ, Kopin IJ. The effects of psychoactive drugs on norepinephrine-3-H metabolism in brain. Biochemical Pharmacology. 16: 393-9. PMID 6029920  1
1967 Schildkraut JJ, Schanberg SM, Breese GR, Kopin IJ. Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action. The American Journal of Psychiatry. 124: 600-8. PMID 4383104  1
1966 Schildkraut JJ, Schanberg SM, Kopin IJ. The effects of lithium ion on H3-norepinephrine metabolism in brain. Life Sciences. 5: 1479-83. PMID 5969204  1
1965 GLOWINSKI J, KOPIN IJ, AXELROD J. METABOLISM OF (H3)NOREPINEPHRINE IN THE RAT BRAIN. Journal of Neurochemistry. 12: 25-30. PMID 14268510  1
1965 FISCHER JE, KOPIN IJ, AXELROD J. EVIDENCE FOR EXTRANEURONAL BINDING OF NOREPINEPHRINE. The Journal of Pharmacology and Experimental Therapeutics. 147: 181-5. PMID 14259495  1
1964 GLOWINSKI J, AXELROD J, KOPIN IJ, WURTMAN RJ. PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT. The Journal of Pharmacology and Experimental Therapeutics. 146: 48-53. PMID 14221225  1
1964 FISCHER JE, MUSACCHIO J, KOPIN IJ, AXELROD J. EFFECTS OF DENERVATION ON THE UPTAKE AND BETA-HYDROXYLATION OF TYRAMINE IN THE RAT SALIVARY GLAND. Life Sciences. 3: 413-9. PMID 14198482  1
1964 ROSELL S, AXELROD J, KOPIN IJ. RELEASE OF TRITIATED EPINEPHRINE FOLLOWING SYMPATHETIC NERVE STIMULATION. Nature. 201: 301. PMID 14110461  1
1963 WURTMAN RJ, AXELROD J, KOPIN IJ. UTERINE EPINEPHRINE AND BLOOD FLOW IN PREGNANT AND POSTPARTURIENT RATS. Endocrinology. 73: 501-3. PMID 14068838 DOI: 10.1210/endo-73-4-501  1
1963 ROSELL S, KOPIN IJ, AXELROD J. FATE OF H3-NORADRENALINE IN SKELETAL MUSCLE BEFORE AND FOLLOWING SYMPATHETIC STIMULATION. The American Journal of Physiology. 205: 317-21. PMID 14058108  1
1963 KOPIN IJ, AXELROD J. The role of monoamine oxidase in the release and metabolism of norepinephrine. Annals of the New York Academy of Sciences. 107: 848-55. PMID 14034691  1
1963 WURTMAN RJ, KOPIN IJ, AXELROD J. Thyroid function and the cardiac disposition of catecholamines. Endocrinology. 73: 63-74. PMID 14002085 DOI: 10.1210/endo-73-1-63  1
1962 POTTER LT, AXELROD J, KOPIN IJ. Differential binding and release of norepinephrine and tachyphylaxis. Biochemical Pharmacology. 11: 254-6. PMID 14488294  1
1962 AXELROD J, GORDON E, HERTTING G, KOPIN IJ, POTTER LT. On the mechanism of tachyphylaxis to tyramine in the isolated rat heart. British Journal of Pharmacology and Chemotherapy. 19: 56-63. PMID 13863453  1
1961 KOPIN IJ, PARE CM, AXELROD J, WEISSBACH H. The fate of melatonin in animals. The Journal of Biological Chemistry. 236: 3072-5. PMID 14458327  1
1961 LABROSSE EH, AXELROD J, KOPIN IJ, KETY SS. Metabolism of 7-H3-epinephrine-d-bitartrate in normal young men. The Journal of Clinical Investigation. 40: 253-60. PMID 13758034 DOI: 10.1172/JCI104251  1
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