Gerrit J. Koomen - Publications

Affiliations: 
1992-2006 chemistry University of Amsterdam, Amsterdam, Netherlands 
Area:
bio-organic chemistry

61/131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Ghisaidoobe AT, van den Berg RJ, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AM, Koomen GJ, van Loevezijn A, Leemhuis M, Wennekes T, van der Stelt M, van der Marel GA, van Boeckel CA, Aerts JM, et al. Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. Journal of Medicinal Chemistry. 57: 9096-104. PMID 25250725 DOI: 10.1021/jm501181z  0.462
2001 Burm BEA, Blokker P, Jongmans E, Van Kampen E, Wanner MJ, Koomen GJ. Synthesis of xestomanzamines a and b Heterocycles. 55: 495-503. DOI: 10.3987/Com-00-9107  0.364
2000 Deghati PYF, Wanner MJ, Koomen GJ. Regioselective nitration of purine nucleosides: Synthesis of 2- nitroadenosine and 2-nitroinosine Tetrahedron Letters. 41: 1291-1295. DOI: 10.1016/S0040-4039(99)02271-6  0.334
1999 Madre M, Panchenko N, Golbraikh A, Zhuk R, Pandit UK, Geenevasen J, Koomen GJ. Purine nucleoside analogues. 11. An alternative synthesis of N- and O-alkyl derivatives of 9- and 7-[(2-acetoxyethoxy)methyl]-N2-acetylguanine Collection of Czechoslovak Chemical Communications. 64: 685-695. DOI: 10.1135/Cccc19990685  0.56
1999 Barends J, Van Der Linden JB, Van Delft FL, Koomen GJ. Palladium-catalyzed amination of 6-chloropurine. Synthesis of N6- substituted adenosine analogues Nucleosides and Nucleotides. 18: 2121-2126.  0.364
1998 Overkleeft HS, Renkema GH, Neele J, Vianello P, Hung IO, Strijland A, van der Burg AM, Koomen GJ, Pandit UK, Aerts JM. Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase. The Journal of Biological Chemistry. 273: 26522-7. PMID 9756888 DOI: 10.1074/jbc.273.41.26522  0.567
1998 Burm BEA, Meijler MM, Korver J, Wanner MJ, Koomen GJ. Synthesis of the brominated marine alkaloids (±)-arborescidine A, B and C Tetrahedron. 54: 6135-6146. DOI: 10.1016/S0040-4020(98)00306-8  0.307
1997 Wanner MJ, Koomen GJ. Biomimetic synthesis of racemic alkaloids Pharmacochemistry Library. 28: 179-187. DOI: 10.1016/S0165-7208(97)80064-5  0.317
1997 Wanner MJ, Koomen GJ. Biomimetic Synthesis of Nitraria Alkaloids, based on Tetrahydropyridine Synthons Journal of the Indian Chemical Society. 74: 891-895.  0.302
1996 Petra DGI, De Boer RF, Koomen GJ, Meeuwenoord NJ, Kuyl-Yeheskiely E, Van Der Marel GA, Van Boom JH. Synthesis and properties of a fluorescent nucleotide derivative Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands. 115: 99-102. DOI: 10.1002/Recl.19961150117  0.39
1995 Wanner MJ, Koomen GJ. Biomimetic synthesis of nitraramine The Journal of Organic Chemistry. 60: 5634-5637.  0.301
1995 Madre M, Geita L, Zhuk R, Koomen GJ. Purine nucleoside analogues. 7. 9-[2-(Alkylthio)ethoxymethyl] derivatives of adenine, hypoxanthine and guanine Chinese Pharmaceutical Journal. 47: 469-481.  0.308
1994 Wanner MJ, Koomen GJ. Biomimetic synthesis of nazlinin and nitrarine Pure and Applied Chemistry. 66: 2239-2242. DOI: 10.1351/pac199466102239  0.301
1994 Boogaard AT, Pandit UK, Koomen GJ. Ring D modifications of ellipticine. Part 2. Chlorination of ellipticine via its N-oxide and synthesis and selective acetylation of 5,6,11-trimethyl-5H-benzo[b]carbazole. Tetrahedron. 50: 4811-4828. DOI: 10.1016/S0040-4020(01)85018-3  0.539
1992 Hartgers WA, De Boer RF, Wanner MJ, Koomen GJ. A potential suicide inhibitor of adenylosuccinate lyase Nucleosides and Nucleotides. 11: 1325-1332. DOI: 10.1080/07328319208021176  0.319
1992 Koomen GJ, Provoost LM, Van Maarschalkerwaart DAH, Willard NP. Synthesis of an acyclic analogue of azidothymidine Nucleosides and Nucleotides. 11: 1297-1303. DOI: 10.1080/07328319208021174  0.337
1992 Plug JPM, Koomen GJ, Pandit UK. An expedient synthesis of 9-hydroxyellipticine Synthesis. 1221-1222. DOI: 10.1055/S-1992-26342  0.517
1992 Vloon WJ, van den Bos JC, Koomen GJ, Pandit UK. Synthesis of ring C modified sesbanimide analogues Tetrahedron. 48: 8317-8328. DOI: 10.1016/S0040-4020(01)80499-3  0.537
1992 Plug JPM, Koomen GJ, Pandit UK. Sythesis of novel annulated ellipticines via Claisen rearrangement reactions Tetrahedron Letters. 33: 2179-2182. DOI: 10.1016/0040-4039(92)88171-Z  0.577
1991 Wanner MJ, Koomen GJ. Biomimetic synthesis of quinolizidine alkaloids Tetrahedron. 47: 8431-8442. DOI: 10.1016/S0040-4020(01)96184-8  0.314
1991 van den Bos JC, Vloon WJ, Koomen GJ, Pandit UK. Synthesis of acyclic analogues of sesbanimides A and B Tetrahedron. 47: 6787-6794. DOI: 10.1016/S0040-4020(01)82330-9  0.562
1990 Van Maarschalkerwaart DAH, Willard NP, Koomen GJ. Carbocyclic nucleoside analogues. Synthesis and properties of 1-(4-hydroxymethyl-2-cyclopenten-1-yl)-thymine Nucleosides and Nucleotides. 9: 787-791. DOI: 10.1080/15257779008043144  0.321
1989 Langendoen A, Plug JPM, Koomen GJ, Pandit UK. Regiospecific C-9 substitution of ellipticine derivatives Tetrahedron. 45: 1759-1762. DOI: 10.1016/S0040-4020(01)80040-5  0.514
1988 Wanner MJ, Koomen GJ. 2-Substituted Glutarimides via Preformed Wittig Reagents Synthesis. 1988: 325-327. DOI: 10.1055/S-1988-27558  0.304
1988 Langendoen A, Koomen GJ, Pandit UK. An approach to novel ellipticine glycosides Tetrahedron. 44: 3627-3631. DOI: 10.1016/S0040-4020(01)85992-5  0.546
1988 WANNER MJ, KOOMEN G. ChemInform Abstract: 2-Substituted Glutarimides via Preformed Wittig Reagents. Cheminform. 19. DOI: 10.1002/CHIN.198833239  0.303
1987 Langendoen A, Koomen GJ, Pandit UK. A new approach to C-9 hydroxylation of N(6)-substituted ellipticine Heterocycles. 26: 91-94. DOI: 10.3987/R-1987-01-0091  0.495
1987 Langendoen A, Koomen GJ, Pandit UK. Side-chain substitution of 6-methylellipticine approach to a new class of ellipticine derivatives Heterocycles. 26: 69-73. DOI: 10.3987/R-1987-01-0069  0.468
1987 Wanner MJ, Willard NP, Koomen GJ, Pandit UK. Stereospecific synthesis of (+)- and (-)-sesbanimide A Tetrahedron. 43: 2549-2556. DOI: 10.1016/S0040-4020(01)81662-8  0.541
1986 Wijsmuller WFA, Wanner MJ, Koomen GJ, Pandit UK. Pyridocarbazole alkaloids. Synthesis of olivacine and ellipticine analogues Heterocycles. 24: 1795-1797. DOI: 10.1002/Chin.198647359  0.566
1986 Koomen GJ, Wolschrijn H, van Rhijn JBM, Wanner MJ, Pandit UK. Synthesis of 5-fluoro-3-(2-tetrahydrofuryl)-6-vinyluracil. Design of a 5-fu-derivative with extended conjugation Heterocycles. 24: 939-941. DOI: 10.1002/Chin.198642214  0.519
1986 Wanner MJ, Willard NP, Koomen GJ, Pandit UK. Synthesis of (7R,8S,9R,10S,11S)-sesbanimide A Journal of the Chemical Society - Series Chemical Communications. 396-397. DOI: 10.1002/Chin.198634331  0.418
1985 Koomen GJ, van Rhijn JBMv, Pandit UK. Non-glycosidic derivatives of 5-fluorouracil Nucleosides and Nucleotides. 4: 215-216. DOI: 10.1080/07328318508077858  0.476
1985 Odijk WM, Koomen GJ. Fluorescent nucleoside analogues. Synthesis of fluorescent pyrido[2,1-i]purines, and their corresponding ribosides Tetrahedron. 41: 1893-1904. DOI: 10.1016/S0040-4020(01)96552-4  0.443
1984 WANNER MJ, KOOMEN G, PANDIT UK. ChemInform Abstract: STUDIES IN THE STEREOSPECIFIC SYNTHESIS OF SESBANIMIDE. SYNTHESIS OF 4-SACCHARIDALGLUTARIMIDES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198448332  0.557
1983 Wanner MJ, Koomen GJ, Pandit UK. Inter- and intramolecular addition of ester anions to nicotinium salts. A facile approach to nauclefine and ellipticine derivatives Tetrahedron. 39: 3673-3681. DOI: 10.1016/S0040-4020(01)88606-3  0.62
1983 WANNER MJ, KOOMEN G, PANDIT UK. ChemInform Abstract: A CONVENIENT SYNTHESIS OF 6-METHYLELLIPTICINE AND 6-METHYLOLIVACINE Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198322343  0.559
1982 Wanner MJ, Koomen GJ, Pandit UK. Synthesis of polynuclear heterocycles via the reaction of α-ester carbanions with quaternized nicotinamide salts. A facile stereoselective synthesis of sesbanine Tetrahedron. 38: 2741-2748. DOI: 10.1016/0040-4020(82)80032-X  0.615
1982 WANNER MJ, KOOMEN G, PANDIT UK. ChemInform Abstract: A New Approach to Ellipticine Analogues; Synthesis of 11-Hydroxy-5,6-dimethyl-pyrido[4,3-b]carbazole. Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198233202  0.542
1980 Wanner MJ, Hageman JJ, Koomen GJ, Pandit UK. Potential carcinostatics. 4. Synthesis and biological properties of erythro- and threo-beta-fluoroaspartic acid and erythro-beta-fluoroasparagine. Journal of Medicinal Chemistry. 23: 85-7. PMID 7359517 DOI: 10.1021/Jm00175A017  0.548
1980 Wanner MJ, Van Wijk EM, Koomen GJ, Pandit UK. Potential carcinostatics. V. Synthesis and properties of potential inhibitors of the adenylosuccinate synthetase and adenylosuccinate lyase system Recueil Des Travaux Chimiques Des Pays Bas. 99: 20-23. DOI: 10.1002/Recl.19780970711  0.609
1980 Wanner MJ, Hageman JJM, Koomen GJ, Pandit UK. POTENTIAL CARCINOSTATICS. 4. SYNTHESIS AND BIOLOGICAL PROPERTIES OF ERYTHRO- AND THREO-β-FLUOROASPARTIC ACID AND ERYTHRO-β-FLUOROASPARAGINE Cheminform. 11. DOI: 10.1002/Chin.198024111  0.503
1979 ODIJK WM, WANNER MJ, KOOMEN GJ, PANDIT UK. ChemInform Abstract: POTENTIAL CARCINOSTATIC AGENTS. PART III. PSEUDO-GLYCOSIDIC DERIVATIVES OF 5-FLUOROURACIL Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197909223  0.515
1978 Wanner MJ, Hageman JJM, Koomen GJ, Pandit UK. Potential Carcinostatics. Part Ii. Synthesis And Properties Of Potential Inhibitors Of The Adenylosuccinate Synthetase And Adenylosuccinate Lyase Systems Cheminform. 11. DOI: 10.1002/Chin.197843246  0.521
1978 HAGEMAN JJM, WANNER MJ, KOOMEN GJ, PANDIT UK. ChemInform Abstract: POTENTIAL CARCINOSTATICS. SYNTHESIS AND BIOLOGICAL PROPERTIES OF D- AND L-β,β-DIFLUOROASPARTIC ACID AND β,β-DIFLUOROASPARAGINE Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197816128  0.489
1978 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGS. XVIII. RING EXPANSION OF URIDINE HALOCARBENE ADDUCTS. SYNTHESIS OF DIAZEPINE NUCLEOSIDES Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197802343  0.341
1978 Wanner MJ, Hageman JJM, Koomen GJ, Pandit UK. Potential carcinostatics. Synthesis and properties of potential inhibitors of the adenylosuccinate synthetase and adenylosuccinate lyase systems Recueil Des Travaux Chimiques Des Pays Bas. 97: 211-214.  0.479
1977 Hageman JJ, Wanner MJ, Koomen GJ, Pandit UK. Potential carcinostatics. Synthesis and biological properties of d- and 1-beta,beta-difluoroaspartic acid and beta,beta-difluoroasparagine. Journal of Medicinal Chemistry. 20: 1677-9. PMID 592334 DOI: 10.1021/Jm00222A029  0.471
1977 Thiellier HPM, Koomen GJ, Pandit UK. Unconventional nucleotide analogues1 1 Part XV. H.P.M Thiellier, G.J. Koomen and U.K. Pandit, Heterocycles 5, 19 (1976). Reaction of carbenes with uracil and uridine derivatives Tetrahedron. 33: 1493-1500. DOI: 10.1016/0040-4020(77)88011-3  0.587
1977 Thiellier HPM, Koomen GJ, Pandit UK. Unconventional nucleotide analogues-XVIII1 1 Part XVII. H.P.M. Thiellier, G.J. Koomen and U.K. Pandit, Tetrahedron 33, 2603 (1977). Ring expansion of uridine halocarbene adducts. Synthesis of diazepine nucleosides Tetrahedron. 33: 2609-2612. DOI: 10.1016/0040-4020(77)80087-2  0.603
1977 Thiellier HPM, Koomen GJ, Pandit UK. Unconventional nucleotide analogues-XVII1 1 Part XVI. H.P.M. Thiellier, G.J. Koomen and U.K. Pandit, Tetrahedron 33, 1493 (1977). Ring-transformations of uracil dihalocarbene adducts Tetrahedron. 33: 2603-2607. DOI: 10.1016/0040-4020(77)80086-0  0.585
1977 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGS. XV. NOVEL BASE-MODIFIED NUCLEOSIDES Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/Chin.197717341  0.539
1976 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: TRANSFORMATIONS OF 1,3-DISUBSTITUTED URACIL-CARBENE ADDUCTS. RING EXPANSION TO 1,3-DIAZEPINE DERIVATIVES Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197603227  0.559
1974 THIELLIER HPM, BURG AMVD, KOOMEN GJ, PANDIT UK. ChemInform Abstract: REACTION OF CARBENES WITH 1,3-DISUBSTITUTED URACIL DERIVATIVES Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197451349  0.55
1973 Koomen GJ, Pandit UK. Unconventional nucleotide analogues. IX. N-substituted 3-(pyrimidin-1-yl) pyrrolidin-2-ones. Journal of the Chemical Society. Perkin Transactions 1. 17: 1929-33. PMID 4799178 DOI: 10.1039/P19730001929  0.57
1973 Koomen GJ, Kroon AP, Mas Cabré FR, Goores AP, Peereboom R, Pandit UK. Unconventional nucleotide analogues. Part X. Synthesis of N-substituted 3-(Adenin-9-yl)pyrrolidin-2-ones Journal of the Chemical Society, Perkin Transactions 1. 1934-1940. PMID 4363162 DOI: 10.1039/P19730001934  0.599
1973 KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGUES PART 9, N-SUBSTITUTED 3-(PYRIMIDIN-1-YL)-PYRROLIDIN-2-ONES Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197349468  0.546
1971 Koomen GJ, Kroon AP, Goores AP, Pandit UK. Non-Sacccfaridal Nucleoside and Hucleotide Analocuses Synthetic Communications. 1: 41-45. DOI: 10.1080/00397917108081615  0.421
1971 KOOMEN GJ, KROON AP, GOORES AP, PANDIT UK. ChemInform Abstract: ZUCKERFREIE NUCLEOSID- UND NUCLEOTID-ANALOGA Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197139334  0.519
1969 Nollet AJH, Koomen GJ, Grose WFA, Pandit UK. Application of NMR spectroscopy in distinguishing between N1- and N3-substituted 2,4-dioxo-1,2,3,4,-tetrahydropyrimidines. Tetrahedron Letters. 10: 4607-4608. DOI: 10.1016/S0040-4039(01)88762-1  0.467
1967 Pandit UK, de Jonge K, Koomen GJ, Huisman HO. Heterocyclic steroids IX. A Convenient Synthesis of 14-Aza-11-Keto Steroids Tetrahedron Letters. 8: 3529-3533.  0.688
Low-probability matches (unlikely to be authored by this person)
2008 Läppchen T, Pinas VA, Hartog AF, Koomen GJ, Schaffner-Barbero C, Andreu JM, Trambaiolo D, Löwe J, Juhem A, Popov AV, den Blaauwen T. Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites. Chemistry & Biology. 15: 189-99. PMID 18291323 DOI: 10.1016/J.Chembiol.2007.12.013  0.299
1998 Madre M, Zhuk R, Panchenko N, Geenevasen J, Van Den Burg A, Koomen GJ. Purine nucleoside analogues. 10. A new synthetic route to 8-substituted-7(9)-alkoxyalkylguanines Heterocyclic Communications. 4: 581-586.  0.293
1994 Wanner MJ, Koomen GJ. Stereoselective synthesis of the indole alkaloids nitrarine, nitramidine, and isomers. A biomimetic approach Journal of Organic Chemistry. 59: 7479-7484.  0.293
2004 Wanner MJ, Rodenko B, Koch M, Koomen GJ. New (1-deaza)purine derivatives via efficient C-2 nitration of the (1-deaza)purine ring. Nucleosides, Nucleotides & Nucleic Acids. 23: 1313-20. PMID 15571251 DOI: 10.1081/NCN-200027566  0.292
1990 Wanner MJ, Koomen GJ. Glutarimide nucleosides synthesis and properties of analogs of 1-deaza-thymidine Tetrahedron Letters. 31: 907-910. DOI: 10.1016/S0040-4039(00)94660-4  0.288
2010 BURM BEA, MEIJLER MM, KORVER J, WANNER MJ, KOOMEN G. ChemInform Abstract: Synthesis of the Brominated Marine Alkaloids (.+-.)-Arborescidine A (IV), B (VIII), and C (VI). Cheminform. 29: no-no. DOI: 10.1002/CHIN.199835262  0.279
1992 Wanner MJ, Koomen GJ. Biomimetic synthesis of nitraria alkaloids: stereoselective spirocyclization reactions Tetrahedron. 48: 3935-3944. DOI: 10.1016/S0040-4020(01)88473-8  0.272
2000 Deghati PYF, Bieräugel H, Wanner MJ, Koomen GJ. Mild and regioselective nitration of 1-deazapurine nucleosides using TBAN/TFAA Tetrahedron Letters. 41: 569-573. DOI: 10.1016/S0040-4039(99)02073-0  0.261
2000 Wanner MJ, Deghati PYF, Rodenko B, Koomen GJ. New nucleoside analogs, synthesis, and biological properties Pure and Applied Chemistry. 72: 1705-1708.  0.26
2005 Rodenko B, Koch M, van der Burg AM, Wanner MJ, Koomen GJ. The mechanism of selective purine C-nitration revealed: NMR studies demonstrate formation and radical rearrangement of an N7-nitramine intermediate. Journal of the American Chemical Society. 127: 5957-63. PMID 15839695 DOI: 10.1021/ja042590x  0.26
2010 Koomen GJ. Selective Fluorination in Organic and Bioorganic Chemistry. John T. Welch, ed. ACS, Washington D. C. 1991. VIII + 215 pp., $57.95. ISBN 0-8412-1948-6 Recueil Des Travaux Chimiques Des Pays-Bas. 110: 392-392. DOI: 10.1002/Recl.19911100914  0.259
1998 Gremmen C, Burm BEA, Wanner MJ, Koomen GJ. The synthesis of new heterocyclic bridged ring systems. Analogs of tetrahydro-β-carbolines Tetrahedron Letters. 39: 1441-1444. DOI: 10.1016/S0040-4039(97)10823-1  0.254
1993 Koomen GJ. Synthesis and biological properties of selected nucleoside analogues Recueil Des Travaux Chimiques Des Pays-Bas. 112: 51-65.  0.252
1977 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGS. PART XV. REACTION OF CARBENES WITH URACIL AND URIDINE DERIVATIVES Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197738358  0.251
2001 Wanner MJ, Koomen GJ. Synthesis and properties of 2-nitrosoadenosine Journal of the Chemical Society. Perkin Transactions 1. 1908-1915.  0.25
2002 Wanner MJ, Koomen GJ. A new synthesis of temozolomide Journal of the Chemical Society. Perkin Transactions 1. 1877-1880.  0.248
1987 Odijk WM, Koomen GJ. Pyrido[2,1-i]-purines: a new class of fluorescent stains. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 35: 1161-3. PMID 3624854 DOI: 10.1177/35.10.3624854  0.248
2002 Rodenko B, Wanner MJ, Koomen GJ. Solid phase synthesis of C2,N6-disubstituted adenosine analogues Journal of the Chemical Society. Perkin Transactions 1. 1247-1252.  0.24
1993 Veloo RA, Koomen GJ. Synthesis of enantiomerically pure (S)-(-)-propranolol from sorbitol Tetrahedron: Asymmetry. 4: 2401-2404. DOI: 10.1016/S0957-4166(00)82209-0  0.236
1995 de Boer RF, Petra DGI, Wanner MJ, Boesaart A, Koomen GJ. Mechanism of formation of fluorescent adenosine analogues Heterocycles. 41: 1197-1206. DOI: 10.3987/Com-94-7007  0.235
2005 Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of Biological Chemistry. 280: 4219-27. PMID 15557326 DOI: 10.1074/Jbc.M411338200  0.233
2010 Koomen GJ. Fluorine in Bioorganic Chemistry. J. T. Welch and S. Eswarakrishnan. John Wiley & Sons, Chichester, 1991. XVIII + 261 pp., £47.50. ISBN 0-471-50649-4 Recueil Des Travaux Chimiques Des Pays-Bas. 110: 391-391. DOI: 10.1002/Recl.19911100913  0.229
1996 Wanner MJ, Koomen GJ. Biomimetic syntheses of alkaloids based on tetrahydropyridine Pure and Applied Chemistry. 68: 2051-2056.  0.227
1987 Odijk WM, Koomen GJ. Aminolysis of pyrido[2,1-i]purines Journal of the Chemical Society, Perkin Transactions 2. 733-737. DOI: 10.1039/P29870000733  0.224
1978 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGS. XVII. RING-TRANSFORMATIONS OF URACIL DIHALOCARBENE ADDUCTS Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197802260  0.223
1993 Koomen GJ. Progress in Heterocyclic Chemistry vol. 3 H. Suschitzky and E.F.V. Scriven, eds. Pergamon Press, UK 1991 ISBN 008 0405894 hard £55.00/$95.00 ISBN 008 0405886 soft £28.00/$50.00 Recueil Des Travaux Chimiques Des Pays-Bas. 112: 315-315. DOI: 10.1002/Recl.19931120508  0.221
1988 Wanner MJ, Koomen GJ. Potential antiviral agents. Synthesis and properties of glutarimide-nucleosides Nucleosides and Nucleotides. 7: 511-517. DOI: 10.1080/07328318808075393  0.22
2007 Rodenko B, van der Burg AM, Wanner MJ, Kaiser M, Brun R, Gould M, de Koning HP, Koomen GJ. 2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial Agents and Chemotherapy. 51: 3796-802. PMID 17698622 DOI: 10.1128/AAC.00425-07  0.217
2007 Glavinas H, Kis E, Pál A, Kovács R, Jani M, Vági E, Molnár E, Bánsághi S, Kele Z, Janáky T, Báthori G, von Richter O, Koomen GJ, Krajcsi P. ABCG2 (breast cancer resistance protein/mitoxantrone resistance-associated protein) ATPase assay: a useful tool to detect drug-transporter interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1533-42. PMID 17537873 DOI: 10.1124/Dmd.106.014605  0.213
2010 Koomen GJ. Progress in Heterocyclic Chemistry, vol. 2. H. Suschitzky and E. F. V. Scriven. Pergamon press, Oxford, U.K. 1990. VIII + 295 pp., £42.00 hard, £21.00 soft. ISBN 008 0370691 hard. ISBN 008 0370705 soft Recueil Des Travaux Chimiques Des Pays-Bas. 111: 198-198. DOI: 10.1002/Recl.19921110408  0.21
1998 Van Loevezijn A, Van Maarseveen JH, Stegman K, Visser GM, Koomen GJ. Solid phase synthesis of fumitremorgin, verruculogen and tryprostatin analogs based on a cyclization/cleavage strategy Tetrahedron Letters. 39: 4737-4740. DOI: 10.1016/S0040-4039(98)00931-9  0.204
1999 Madre M, Panchenko N, Zhuk R, Geenevasen JA, Van Den Burg A, Koomen GJ. Purine nucleoside analogues; 9: Benzylation of N2-acetyl-8- bromoguanine Synthesis. 775-778.  0.204
1995 De Boer RF, Petra DGI, Wanner MJ, Boesaart A, Koomen GJ. Synthesis of fluorescent adenosine analogues Nucleosides and Nucleotides. 14: 349-352.  0.204
2010 Verhoeven JW, Koomen GJ, van der Kerk SM. Resonant tunnelling as a possible source of catalysis by energy-matched enzymes Recueil Des Travaux Chimiques Des Pays-Bas. 105: 343-344. DOI: 10.1002/Recl.19861050920  0.202
2000 Wanner MJ, Von Frijtag Drabbe Künzel JK, Ijzerman AP, Koomen GJ. 2-Nitro analogues of adenosine and 1-deazaadenosine: synthesis and binding studies at the adenosine A1, A2A and A3 receptor subtypes. Bioorganic & Medicinal Chemistry Letters. 10: 2141-4. PMID 10999489 DOI: 10.1016/S0960-894X(00)00415-7  0.201
1993 Wanner MJ, Velzel AW, Koomen GJ. Biomimetic synthesis of nazlinin: A structural revision Journal of the Chemical Society - Series Chemical Communications. 174-175. DOI: 10.1039/C39930000174  0.2
2001 Burm BEA, Gremmen C, Wanner MJ, Koomen GJ. Synthesis of new bridged tetrahydro-β-carbolines and spiro-fused quinuclidines Tetrahedron. 57: 2039-2049. DOI: 10.1016/S0040-4020(01)00023-0  0.199
2000 Gremmen C, Willemse B, Wanner MJ, Koomen GJ. Enantiopure Tetrahydro-beta-carbolines via Pictet-Spengler Reactions with N-Sulfinyl Tryptamines. Organic Letters. 2: 1955-1958. PMID 10891200  0.193
2006 Rodenko B, Detz RJ, Pinas VA, Lambertucci C, Brun R, Wanner MJ, Koomen GJ. Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues. Bioorganic & Medicinal Chemistry. 14: 1618-29. PMID 16249090 DOI: 10.1016/j.bmc.2005.10.011  0.177
1993 Trang NT, Wanner MJ, Koomen GJ, Dung NX. New Acetophenone and Thymol Derivatives from Eupatorium stoechadosmum. Planta Medica. 59: 480-1. PMID 17236013 DOI: 10.1055/s-2006-959741  0.176
1998 Deghati PYF, Wanner MJ, Koomen GJ. An efficient hetero Diels-Alder approach to imidazo[4,5-c]pyridazines as purine analogues Tetrahedron Letters. 39: 4561-4564. DOI: 10.1016/S0040-4039(98)00806-5  0.174
2001 Gremmen C, Wanner MJ, Koomen GJ. Enantiopure tetrahydroisoquinolines via N-sulfinyl Pictet-Spengler reactions Tetrahedron Letters. 42: 8885-8888. DOI: 10.1016/S0040-4039(01)01854-8  0.174
2004 Wanner MJ, Koch M, Koomen GJ. Synthesis and antitumor activity of methyltriazene prodrugs simultaneously releasing DNA-methylating agents and the antiresistance drug O(6)-benzylguanine. Journal of Medicinal Chemistry. 47: 6875-83. PMID 15615536 DOI: 10.1021/jm049556d  0.169
2000 Gremmen C, Willemse B, Wanner MJ, Koomen GJ. Enantiopure tetrahydro-β-carbolines via Pictet-Spengler reactions with N-sulfinyl tryptamines Organic Letters. 2: 1955-1958.  0.169
1996 Madre M, Zhuk R, Panchenko N, Geenevasen JAJ, van den Burg AM, Koomen G. Some peculiarities of N2-acetyl-8-bromoguanine alkylation Collection of Czechoslovak Chemical Communications. 61: 20-22. DOI: 10.1135/CCCC1996S020  0.168
1995 Cheng E, Dekker HL, van Gelder BF, Koomen GJ. Inhibition of pig kidney diamine oxidase by nazlinin and nazlinin derivatives. Biochimica Et Biophysica Acta. 1253: 189-92. PMID 8519801 DOI: 10.1016/0167-4838(95)00169-5  0.168
1997 Mohar B, Kobe J, Koomen GJ. Approach to carbocyclic 4-deoxypyrazofurin through asymmetrisation of a meso-norbornene derivative Synlett. 1467-1468.  0.166
1998 Wanner MJ, Koomen GJ. Synthesis of the Cyclostellettamines A-F and Related Bis(3-alkylpyridinium) Macrocycles European Journal of Organic Chemistry. 889-895.  0.162
1975 KOOMEN GJ, PANDIT UK. ChemInform Abstract: THE ′HILBERT-JOHNSON′ REACTION OF 3,5-DIETHOXY-1,2,4-THIADIAZOLE Chemischer Informationsdienst. 6. DOI: 10.1002/chin.197548301  0.159
2011 Rodenko B, Al-Salabi MI, Teka IA, Ho W, El-Sabbagh N, Ali JA, Ibrahim HM, Wanner MJ, Koomen GJ, de Koning HP. Synthesis of marine-derived 3-alkylpyridinium alkaloids with potent antiprotozoal activity. Acs Medicinal Chemistry Letters. 2: 901-6. PMID 24900279 DOI: 10.1021/ml200160k  0.155
1996 Cheng E, Botzem J, Wanner MJ, Burnt BEA, Koomen GJ. Enzyme catalysed oxidation of nazlinin and nazlinin derivatives. Characterisation of the reaction products Tetrahedron. 52: 6725-6732. DOI: 10.1016/0040-4020(96)00286-4  0.153
1992 Veloo RA, Wanner MJ, Koomen GJ. Stereoselective formation of tetrahydrofurans during allyltrimethylsilane additions to L-xylose derivatives Tetrahedron. 48: 5301-5316. DOI: 10.1016/S0040-4020(01)89027-X  0.151
1997 Madre M, Zhuk R, Koomen GJ. Addition of 2,3-dihydrofuran to N2-acetyl-8-bromoguanine Nucleosides and Nucleotides. 16: 1107-1110.  0.14
2003 Beukers MW, Wanner MJ, Von Frijtag Drabbe Künzel JK, Klaasse EC, IJzerman AP, Koomen GJ. N6-cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a very selective agonist with high affinity for the human adenosine A1 receptor. Journal of Medicinal Chemistry. 46: 1492-503. PMID 12672250 DOI: 10.1021/jm021074j  0.136
2005 Läppchen T, Hartog AF, Pinas VA, Koomen GJ, den Blaauwen T. GTP analogue inhibits polymerization and GTPase activity of the bacterial protein FtsZ without affecting its eukaryotic homologue tubulin. Biochemistry. 44: 7879-84. PMID 15910002 DOI: 10.1021/bi047297o  0.133
2001 van Loevezijn A, Allen JD, Schinkel AH, Koomen GJ. Inhibition of BCRP-mediated drug efflux by fumitremorgin-type indolyl diketopiperazines. Bioorganic & Medicinal Chemistry Letters. 11: 29-32. PMID 11140726 DOI: 10.1016/S0960-894X(00)00588-6  0.122
1996 Kroon AR, Hoff WD, Fennema HP, Gijzen J, Koomen GJ, Verhoeven JW, Crielaard W, Hellingwerf KJ. Spectral tuning, fluorescence, and photoactivity in hybrids of photoactive yellow protein, reconstituted with native or modified chromophores. The Journal of Biological Chemistry. 271: 31949-56. PMID 8943241 DOI: 10.1074/Jbc.271.50.31949  0.12
1998 Cordfunke R, Kort R, Pierik A, Gobets B, Koomen GJ, Verhoeven JW, Hellingwerf KJ. Trans/cis (Z/E) photoisomerization of the chromophore of photoactive yellow protein is not a prerequisite for the initiation of the photocycle of this photoreceptor protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 7396-401. PMID 9636160 DOI: 10.1073/Pnas.95.13.7396  0.115
2015 Rodenko B, Wanner MJ, Alkhaldi AA, Ebiloma GU, Barnes RL, Kaiser M, Brun R, McCulloch R, Koomen GJ, de Koning HP. Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy. Antimicrobial Agents and Chemotherapy. 59: 6708-16. PMID 26282430 DOI: 10.1128/AAC.00596-15  0.109
2002 Allen JD, van Loevezijn A, Lakhai JM, van der Valk M, van Tellingen O, Reid G, Schellens JH, Koomen GJ, Schinkel AH. Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. Molecular Cancer Therapeutics. 1: 417-25. PMID 12477054  0.101
1997 Jonker SA, Nkunya MHH, Mwamtobe L, Geenevasen J, Koomen GJ. A new coumarin and polyhydroxysqualenes from Ekebergia benguelensis Natural Product Letters. 10: 245-248.  0.072
1992 Wanner MJ, Koomen GJ. New phosphonium ylides by functionalization of triphenylphosphoranylideneacetamide Tetrahedron Letters. 33: 1513-1516. DOI: 10.1016/S0040-4039(00)91662-9  0.071
1989 Compernolle F, Saleh A, Hoornaert G, Damianos N, Galons H, Miocque M, Ouero AM, Cntto J, De Clercq E, Schols D, Baba M, Pauwels R, De Meyer N, Pandey HK, Mishra L, ... ... Koomen GJ, et al. Abstracts of papers Symposium “new therapeutic developments in human infectious diseases” Pharmaceutisch Weekblad. 11: C3-C9. DOI: 10.1007/BF02196043  0.07
1989 Wanner MJ, Koomen GJ. Synthesis of (±)-nitramine, (±)-isonitramine and (±)-sibirine via Diels-Alder reactions Tetrahedron Letters. 30: 2301-2304. DOI: 10.1016/S0040-4039(00)99677-1  0.07
2013 Wielsma S, Gerrits AM, Koomen GJ, Witteman B. Pancreatitis and a sudden loss of sight. The Netherlands Journal of Medicine. 71: 137-141. PMID 23712810  0.058
1986 Odijk WM, Koomen GJ. Photophysical properties of fluorescent pyrido[2,1-i]purines Journal of the Chemical Society, Perkin Transactions 2. 1561-1565. DOI: 10.1039/P29860001561  0.044
1996 Wanner MJ, Koomen GJ. Oxidative deamination of tetrahydroanabasine with o-quinones: An easy entry to lupinine, sparteine, and anabasine Journal of Organic Chemistry. 61: 5581-5586. DOI: 10.1021/jo9602130  0.038
1993 Trang NT, Wanner MJ, Phuong le VN, Koomen GJ, Dung NX. Thymoquinone from Eupatorium ayapana. Planta Medica. 59: 99. PMID 17230346 DOI: 10.1055/s-2006-959619  0.019
1977 Koomen GJ, Thijssen GM, Kruizinga R. Possibilities of tissue diagnosis in ophthalmologic echography [proceedings]. Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift FüR Augenheilkunde. 175: 45-6. PMID 904905  0.018
1985 Nielen MWF, Koomen G, Frei RW, Brinkman UAT. Electrochemical detection of phenylurea herbicides in liquid chromatography Journal of Liquid Chromatography. 8: 315-332. DOI: 10.1080/01483918508067080  0.016
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