Jennifer M. Laing, Ph.D. - Publications

Affiliations: 
2009 Pharmacology and Experimental Therapeutics University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Neuroscience Biology, Virology Biology, Molecular Biology

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Aurelian L, Laing JM, Lee KS. H11/HspB8 and Its Herpes Simplex Virus Type 2 Homologue ICP10PK Share Functions That Regulate Cell Life/Death Decisions and Human Disease. Autoimmune Diseases. 2012: 395329. PMID 23056924 DOI: 10.1155/2012/395329  0.665
2012 Smith CC, Lee KS, Li B, Laing JM, Hersl J, Shvartsbeyn M, Aurelian L. Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways. Cell Death & Disease. 3: e371. PMID 22898869 DOI: 10.1038/Cddis.2012.108  0.688
2010 Laing JM, Smith CC, Aurelian L. Multi-targeted neuroprotection by the HSV-2 gene ICP10PK includes robust bystander activity through PI3-K/Akt and/or MEK/ERK-dependent neuronal release of vascular endothelial growth factor and fractalkine. Journal of Neurochemistry. 112: 662-76. PMID 19891735 DOI: 10.1111/J.1471-4159.2009.06475.X  0.652
2010 Colunga AG, Laing JM, Aurelian L. The HSV-2 mutant DeltaPK induces melanoma oncolysis through nonredundant death programs and associated with autophagy and pyroptosis proteins. Gene Therapy. 17: 315-27. PMID 19798049 DOI: 10.1038/Gt.2009.126  0.739
2008 Burnett JW, Laing JM, Aurelian L. Acute skin eruptions that are positive for herpes simplex virus DNA polymerase in patients with stem cell transplantation: a new manifestation within the erythema multiforme reactive dermatoses. Archives of Dermatology. 144: 902-7. PMID 18645142 DOI: 10.1001/Archderm.144.7.902  0.532
2008 Wales SQ, Laing JM, Chen L, Aurelian L. ICP10PK inhibits calpain-dependent release of apoptosis-inducing factor and programmed cell death in response to the toxin MPP+. Gene Therapy. 15: 1397-409. PMID 18496573 DOI: 10.1038/Gt.2008.88  0.766
2008 Laing JM, Aurelian L. DeltaRR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis. Genetic Vaccines and Therapy. 6: 1. PMID 18179717 DOI: 10.1186/1479-0556-6-1  0.677
2008 Laing JM, Golembewski EK, Wales SQ, Liu J, Jafri MS, Yarowsky PJ, Aurelian L. Growth-compromised HSV-2 vector Delta RR protects from N-methyl-D-aspartate-induced neuronal degeneration through redundant activation of the MEK/ERK and PI3-K/Akt survival pathways, either one of which overrides apoptotic cascades. Journal of Neuroscience Research. 86: 378-91. PMID 17893911 DOI: 10.1002/Jnr.21486  0.772
2007 Laing JM, Gober MD, Golembewski EK, Thompson SM, Gyure KA, Yarowsky PJ, Aurelian L. Corrigendum to "Intranasal Administration of the Growth-compromised HSV-2 Vector ΔRR Prevents Kainate-induced Seizures and Neuronal Loss in Rats and Mice". Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1734. PMID 28182929 DOI: 10.1038/Sj.Mt.6300211  0.586
2007 Wales SQ, Li B, Laing JM, Aurelian L. The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation. Journal of Neurochemistry. 103: 365-79. PMID 17877640 DOI: 10.1111/J.1471-4159.2007.04745.X  0.774
2007 Gober MD, Laing JM, Burnett JW, Aurelian L. The Herpes simplex virus gene Pol expressed in herpes-associated erythema multiforme lesions upregulates/activates SP1 and inflammatory cytokines. Dermatology (Basel, Switzerland). 215: 97-106. PMID 17684370 DOI: 10.1159/000104259  0.578
2007 Li B, Smith CC, Laing JM, Gober MD, Liu L, Aurelian L. Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-beta-activated kinase 1. Oncogene. 26: 3521-31. PMID 17173073 DOI: 10.1038/Sj.Onc.1210145  0.66
2006 Sharma BK, Smith CC, Laing JM, Rucker DA, Burnett JW, Aurelian L. Aberrant DNA methylation silences the novel heat shock protein H11 in melanoma but not benign melanocytic lesions. Dermatology (Basel, Switzerland). 213: 192-9. PMID 17033167 DOI: 10.1159/000095035  0.583
2006 Gober MD, Laing JM, Thompson SM, Aurelian L. The growth compromised HSV-2 mutant DeltaRR prevents kainic acid-induced apoptosis and loss of function in organotypic hippocampal cultures. Brain Research. 1119: 26-39. PMID 17020750 DOI: 10.1016/J.Brainres.2006.08.078  0.719
2006 Laing JM, Gober MD, Golembewski EK, Thompson SM, Gyure KA, Yarowsky PJ, Aurelian L. Intranasal administration of the growth-compromised HSV-2 vector DeltaRR prevents kainate-induced seizures and neuronal loss in rats and mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 870-81. PMID 16500153 DOI: 10.1016/J.Ymthe.2005.12.013  0.62
2006 Laing JM, Gober MD, Aurelian L. 1069. The HSV-2 Vector ΔRR Prevents Excitotoxicity-Induced Neuronal Cell Loss through Activation of Survival Pathways and Glial Cell Modulation Molecular Therapy. 13: S410. DOI: 10.1016/J.Ymthe.2006.08.1168  0.71
2006 Li B, Smith CC, Laing JM, Aurelian L. 960. Forced Expression of the Heat Shock Protein H11 Causes Growth Arrest and Apoptosis of Melanoma Cells through TAK1 Activation and Inhibits Tumor Growth in Xenograft Models Molecular Therapy. 13: S370. DOI: 10.1016/J.Ymthe.2006.08.1052  0.667
2006 Laing J, Gober M, Aurelian L. Excitotoxicity induced neuronal cell loss is prevented by the HSV-2 vector ΔRR through activation of survival pathways and modulation of glial cells Experimental Neurology. 198: 575-576. DOI: 10.1016/J.Expneurol.2006.02.060  0.672
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