Susanna M.O. Hourani, Ph.D. - Publications

Affiliations: 
Health and Medical Sciences University of Surrey, Guildford, England, United Kingdom 
Area:
Adenosine, purinergic receptors

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Georgiou P, Zanos P, Garcia-Carmona JA, Hourani S, Kitchen I, Kieffer BL, Laorden ML, Bailey A. The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26475574 DOI: 10.1016/j.euroneuro.2015.09.015  0.56
2015 Wright SR, Zanos P, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. A critical role of striatal A2A R-mGlu5 R interactions in modulating the psychomotor and drug-seeking effects of methamphetamine. Addiction Biology. PMID 25975203 DOI: 10.1111/adb.12259  1
2014 Georgiou P, Zanos P, Ehteramyan M, Hourani S, Kitchen I, Maldonado R, Bailey A. Differential regulation of mGlu5 R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice. Addiction Biology. PMID 25522112 DOI: 10.1111/adb.12208  0.56
2014 Zanos P, Georgiou P, Wright SR, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 855-65. PMID 24129263 DOI: 10.1038/npp.2013.285  1
2014 Zanos P, Wright SR, Georgiou P, Yoo JH, Ledent C, Hourani SM, Kitchen I, Winsky-Sommerer R, Bailey A. Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism. Pharmacology, Biochemistry, and Behavior. 119: 72-9. PMID 23680573 DOI: 10.1016/j.pbb.2013.05.009  1
2013 Metaxas A, Al-Hasani R, Farshim P, Tubby K, Berwick A, Ledent C, Hourani S, Kitchen I, Bailey A. Genetic deletion of the adenosine A(2A) receptor prevents nicotine-induced upregulation of α7, but not α4β2* nicotinic acetylcholine receptor binding in the brain. Neuropharmacology. 71: 228-36. PMID 23583933 DOI: 10.1016/j.neuropharm.2013.03.023  0.56
2012 Wells L, Opacka-Juffry J, Fisher D, Ledent C, Hourani S, Kitchen I. In vivo dopaminergic and behavioral responses to acute cocaine are altered in adenosine A(2A) receptor knockout mice. Synapse (New York, N.Y.). 66: 383-90. PMID 22213208 DOI: 10.1002/syn.21527  0.56
2012 Hussey MJ, Clarke GD, Ledent C, Kitchen I, Hourani SM. Deletion of the adenosine A(2A) receptor in mice enhances spinal cord neurochemical responses to an inflammatory nociceptive stimulus. Neuroscience Letters. 506: 198-202. PMID 22100661 DOI: 10.1016/j.neulet.2011.11.004  1
2011 Al-Hasani R, Foster JD, Metaxas A, Ledent C, Hourani SM, Kitchen I, Chen Y. Increased desensitization of dopamine Dâ‚‚ receptor-mediated response in the ventral tegmental area in the absence of adenosine A(2A) receptors. Neuroscience. 190: 103-11. PMID 21669258 DOI: 10.1016/j.neuroscience.2011.05.068  1
2010 Thakur S, Du J, Hourani S, Ledent C, Li JM. Inactivation of adenosine A2A receptor attenuates basal and angiotensin II-induced ROS production by Nox2 in endothelial cells Journal of Biological Chemistry. 285: 40104-40113. PMID 20940302 DOI: 10.1074/jbc.M110.184606  0.52
2010 Hussey MJ, Clarke GD, Ledent C, Kitchen I, Hourani SM. Genetic deletion of the adenosine A(2A) receptor in mice reduces the changes in spinal cord NMDA receptor binding and glucose uptake caused by a nociceptive stimulus. Neuroscience Letters. 479: 297-301. PMID 20570711 DOI: 10.1016/j.neulet.2010.05.084  1
2008 Castañé A, Wells L, Soria G, Hourani S, Ledent C, Kitchen I, Opacka-Juffry J, Maldonado R, Valverde O. Behavioural and biochemical responses to morphine associated with its motivational properties are altered in adenosine A(2A) receptor knockout mice. British Journal of Pharmacology. 155: 757-66. PMID 18660831 DOI: 10.1038/bjp.2008.299  0.56
2008 Ribé D, Sawbridge D, Thakur S, Hussey M, Ledent C, Kitchen I, Hourani S, Li JM. Adenosine A2A receptor signaling regulation of cardiac NADPH oxidase activity. Free Radical Biology & Medicine. 44: 1433-42. PMID 18206127 DOI: 10.1016/j.freeradbiomed.2007.12.035  0.56
2007 Ferré S, Diamond I, Goldberg SR, Yao L, Hourani SM, Huang ZL, Urade Y, Kitchen I. Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain. Progress in Neurobiology. 83: 332-47. PMID 17532111 DOI: 10.1016/j.pneurobio.2007.04.002  1
2007 Godfrey L, Bailey I, Toms NJ, Clarke GD, Kitchen I, Hourani SM. Paracetamol inhibits nitric oxide synthesis in murine spinal cord slices. European Journal of Pharmacology. 562: 68-71. PMID 17331495 DOI: 10.1016/j.ejphar.2007.01.075  1
2007 Hussey MJ, Clarke GD, Ledent C, Hourani SM, Kitchen I. Reduced response to the formalin test and lowered spinal NMDA glutamate receptor binding in adenosine A2A receptor knockout mice. Pain. 129: 287-94. PMID 17134834 DOI: 10.1016/j.pain.2006.10.014  1
2006 Godfrey L, Yan L, Clarke GD, Ledent C, Kitchen I, Hourani SM. Modulation of paracetamol antinociception by caffeine and by selective adenosine A2 receptor antagonists in mice. European Journal of Pharmacology. 531: 80-6. PMID 16448647 DOI: 10.1016/j.ejphar.2005.12.004  1
2005 Godfrey L, Morselli A, Bennion P, Clarke GD, Hourani SM, Kitchen I. An investigation of binding sites for paracetamol in the mouse brain and spinal cord. European Journal of Pharmacology. 508: 99-106. PMID 15680259 DOI: 10.1016/j.ejphar.2004.11.061  1
2004 Kelly M, Bailey A, Ledent C, Kitchen I, Hourani S. Characterization of [3H]ZM 241385 binding in wild-type and adenosine A2A receptor knockout mice. European Journal of Pharmacology. 504: 55-9. PMID 15507221 DOI: 10.1016/j.ejphar.2004.09.052  0.56
2004 Bailey A, Weber D, Zimmer A, Zimmer AM, Hourani SM, Kitchen I. Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains of mice deficient in the preproenkephalin gene. Brain Research. 1025: 1-9. PMID 15464738 DOI: 10.1016/j.brainres.2004.06.088  1
2004 Hourani SM. Pharmacological approaches to studying platelet function: an overview. Methods in Molecular Biology (Clifton, N.J.). 273: 73-86. PMID 15308794 DOI: 10.1385/1-59259-783-1:073  1
2004 Bailey A, Davis L, Lesscher HM, Kelly MD, Ledent C, Hourani SM, Kitchen I. Enhanced morphine withdrawal and micro -opioid receptor G-protein coupling in A2A adenosine receptor knockout mice. Journal of Neurochemistry. 88: 827-34. PMID 14756803  1
2003 Bailey A, Hawkins RM, Hourani SM, Kitchen I. Quantitative autoradiography of adenosine receptors in brains of chronic naltrexone-treated mice. British Journal of Pharmacology. 139: 1187-95. PMID 12871838 DOI: 10.1038/sj.bjp.0705340  1
2002 Nicholls J, Hourani SM, Hall JM. Characterization of adenosine receptors mediating the vasodilator effects of adenosine receptor agonists in the microvasculature of the hamster cheek pouch in vivo. Autonomic & Autacoid Pharmacology. 22: 209-14. PMID 12656946 DOI: 10.1046/j.1474-8673.2002.00259.x  0.64
2002 Bailey A, Ledent C, Kelly M, Hourani SM, Kitchen I. Changes in spinal delta and kappa opioid systems in mice deficient in the A2A receptor gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9210-20. PMID 12417646  1
2002 Prentice DJ, Kelly MD, Ledent C, Hourani SM. Relaxation of the mouse isolated aorta and carotid artery in response to adenosine analogues in genetically-modified mice lacking the adenosine A(2A) receptor. Naunyn-Schmiedeberg's Archives of Pharmacology. 366: 127-33. PMID 12122499 DOI: 10.1007/s00210-002-0581-7  0.52
2002 Bailey A, Matthes H, Kieffer B, Slowe S, Hourani SM, Kitchen I. Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains and spinal cords of mice deficient in the mu-opioid receptor gene. Brain Research. 943: 68-79. PMID 12088840 DOI: 10.1016/S0006-8993(02)02536-2  1
2001 Hourani SM, Boon K, Fooks HM, Prentice DJ. Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues. British Journal of Pharmacology. 133: 833-40. PMID 11454656 DOI: 10.1038/sj.bjp.0704140  0.4
2000 Prentice DJ, Hourani SM. Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta. Naunyn-Schmiedeberg's Archives of Pharmacology. 362: 427-34. PMID 11111838 DOI: 10.1007/s002100000292  0.4
2000 Cusack NJ, Hourani SM. Platelet P2 receptors: from curiosity to clinical targets. Journal of the Autonomic Nervous System. 81: 37-43. PMID 10869698 DOI: 10.1016/S0165-1838(00)00151-X  1
1999 Peachey JA, Hourani SM, Kitchen I. Ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat distal colon. Naunyn-Schmiedeberg's Archives of Pharmacology. 359: 140-6. PMID 10048599  1
1998 Hourani SM, Bailey SJ, Johnson CR, Tennant JP. Effects of adenosine 5'-triphosphate, uridine 5'-triphosphate, adenosine 5'-tetraphosphate and diadenosine polyphosphates in guinea-pig taenia caeci and rat colon muscularis mucosae. Naunyn-Schmiedeberg's Archives of Pharmacology. 358: 464-73. PMID 9826069 DOI: 10.1007/PL00005279  0.64
1997 Nicholls J, Hourani SM. Characterization of adenosine receptors on rat ileum, ileal longitudinal muscle and muscularis mucosae. European Journal of Pharmacology. 338: 143-50. PMID 9455996 DOI: 10.1016/S0014-2999(97)81942-5  0.64
1997 Prentice DJ, Payne SL, Hourani SM. Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery. British Journal of Pharmacology. 122: 1509-15. PMID 9421303 DOI: 10.1038/sj.bjp.0701524  0.4
1997 Nicholls J, Skene DJ, Hourani SM. Use of a newly developed technique to isolate rat pinealocytes and study the effects of adenosine agonists on melatonin production. Journal of Pineal Research. 23: 164-8. PMID 9406988  0.64
1997 Brownhill VR, Hourani SM, Kitchen I. Ontogeny of P2-purinoceptors in the longitudinal muscle and muscularis mucosae of the rat isolated duodenum. British Journal of Pharmacology. 122: 225-32. PMID 9313929 DOI: 10.1038/sj.bjp.0701375  1
1997 Prentice DJ, Hourani SM. Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site. European Journal of Pharmacology. 323: 103-6. PMID 9105884 DOI: 10.1016/S0014-2999(97)00113-1  0.4
1997 Prentice DJ, Hourani SMO. Information in agonist curve shape for receptor classification Annals of the New York Academy of Sciences. 812: 234-235. DOI: 10.1111/j.1749-6632.1997.tb48187.x  0.4
1996 Brownhill VR, Hourani SM, Kitchen I. Differential ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat isolated duodenum. European Journal of Pharmacology. 317: 321-8. PMID 8997617 DOI: 10.1016/S0014-2999(96)00721-2  1
1996 Peachey JA, Hourani SM, Kitchen I. Differential development of adenosine A1 and A2b receptors in the rat duodenum. British Journal of Pharmacology. 119: 949-58. PMID 8922745  1
1996 Peachey JA, Brownhill VR, Hourani SM, Kitchen I. The ontogenetic profiles of the pre- and postjunctional adenosine receptors in the rat vas deferens. British Journal of Pharmacology. 117: 1105-10. PMID 8882603  1
1996 Prentice DJ, Hourani SM. Activation of multiple sites by adenosine analogues in the rat isolated aorta. British Journal of Pharmacology. 118: 1509-17. PMID 8832079  0.4
1996 Nicholls J, Brownhill VR, Hourani SM. Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae. British Journal of Pharmacology. 117: 170-4. PMID 8825359  1
1996 Brownhill VR, Hourani SM, Kitchen I. Differential distribution of adenosine A2 receptors in the epididymal and prostatic portions of the rat vas deferens. European Journal of Pharmacology. 303: 87-90. PMID 8804915 DOI: 10.1016/0014-2999(96)00077-5  1
1996 Brownhill VR, Hourani SM, Kitchen I. Selective enhancement by an adenosine A1 receptor agonist of agents inducing contraction of the rat vas deferens. Naunyn-Schmiedeberg's Archives of Pharmacology. 353: 499-504. PMID 8740142  1
1996 Hourani SMO, Welford LA, Cusack NJ. Effects of 2-methylthioadenosine 5'-β,γ-methylenetriphosphonate and 2-ethylthioadenosine 5'-monophosphate on human platelet activation induced by adenosine 5'-diphosphate Drug Development Research. 38: 12-23. DOI: 10.1002/(SICI)1098-2299(199605)38:1<12::AID-DDR2>3.0.CO;2-O  1
1995 Bailey SJ, Hourani SM. Effects of suramin on contractions of the guinea-pig vas deferens induced by analogues of adenosine 5'-triphosphate. British Journal of Pharmacology. 114: 1125-32. PMID 7620701  0.64
1994 Bailey SJ, Hourani SM. Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladder. British Journal of Pharmacology. 112: 219-25. PMID 8032645  0.64
1994 Peachey JA, Hourani SM, Kitchen I. The binding of 1,3-[3H]-dipropyl-8-cyclopentylxanthine to adenosine A1 receptors in rat smooth muscle preparations. British Journal of Pharmacology. 113: 1249-56. PMID 7889280  1
1993 Hourani SM, Nicholls J, Lee BS, Halfhide EJ, Kitchen I. Characterization and ontogeny of P1-purinoceptors on rat vas deferens. British Journal of Pharmacology. 108: 754-8. PMID 8467361  1
1993 Hourani SM, Johnson CR, Bailey SJ. Desensitization of the P2-purinoceptors on the rat colon muscularis mucosae. British Journal of Pharmacology. 110: 501-5. PMID 8220915  0.64
1992 Nicholls J, Hourani SM, Kitchen I. Characterization of P1-purinoceptors on rat duodenum and urinary bladder. British Journal of Pharmacology. 105: 639-42. PMID 1628151  1
1992 Bailey SJ, Hickman D, Hourani SM. Characterization of the P1-purinoceptors mediating contraction of the rat colon muscularis mucosae. British Journal of Pharmacology. 105: 400-4. PMID 1559130  0.64
1992 Bailey SJ, Hourani SM. Effects of purines on the longitudinal muscle of the rat colon. British Journal of Pharmacology. 105: 885-92. PMID 1504717  0.64
1991 Hourani SM, Cusack NJ. Pharmacological receptors on blood platelets. Pharmacological Reviews. 43: 243-98. PMID 1956953  1
1991 Hourani SM, Bailey SJ, Nicholls J, Kitchen I. Direct effects of adenylyl 5'-(beta,gamma-methylene)diphosphonate, a stable ATP analogue, on relaxant P1-purinoceptors in smooth muscle. British Journal of Pharmacology. 104: 685-90. PMID 1797327  1
1991 Hourani SMO, Bailey SJ, Nicholls J, Kitchen I. AMPPCP acts via P1 and not P2 receptors in some isolated smooth muscle preparations Nucleosides and Nucleotides. 10: 1203-1205. DOI: 10.1080/07328319108047276  1
1991 Cusack NJ, Hourani SMO. Design, syntheses and pharmacology of ATP analogues selective for subtypes of P2-purinoceptors Nucleosides and Nucleotides. 10: 1019-1028. DOI: 10.1080/07328319108047239  1
1990 Cusack NJ, Hourani SM. Subtypes of P2-purinoceptors. Studies using analogues of ATP. Annals of the New York Academy of Sciences. 603: 172-81. PMID 2291519  1
1990 Nicholls J, Hourani SM, Kitchen I. The ontogeny of purinoceptors in rat urinary bladder and duodenum. British Journal of Pharmacology. 100: 874-8. PMID 2207506  1
1990 Bailey SJ, Hourani SM. A study of the purinoceptors mediating contraction in the rat colon. British Journal of Pharmacology. 100: 753-6. PMID 1698498  0.64
1988 Hourani SM, Welford LA, Loizou GD, Cusak NJ. Adenosine 5'-(2-fluorodiphosphate) is a selective agonist at P2-purinoceptors mediating relaxation of smooth muscle. European Journal of Pharmacology. 147: 131-6. PMID 3371408 DOI: 10.1016/0014-2999(88)90642-5  0.96
1987 Cusack NJ, Hourani SM, Loizou GD, Welford LA. Pharmacological effects of isopolar phosphonate analogues of ATP on P2-purinoceptors in guinea-pig taenia coli and urinary bladder. British Journal of Pharmacology. 90: 791-5. PMID 3580709  1
1987 Welford LA, Cusack NJ, Hourani SM. The structure-activity relationships of ectonucleotidases and of excitatory P2-purinoceptors: evidence that dephosphorylation of ATP analogues reduces pharmacological potency. European Journal of Pharmacology. 141: 123-30. PMID 2822441 DOI: 10.1016/0014-2999(87)90418-3  1
1986 Hourani SM, Loizou GD, Cusack NJ. Pharmacological effects of L-AMP-PCP on ATP receptors in smooth muscle. European Journal of Pharmacology. 131: 99-103. PMID 3816951 DOI: 10.1016/0014-2999(86)90521-2  1
1986 Welford LA, Cusack NJ, Hourani SM. ATP analogues and the guinea-pig taenia coli: a comparison of the structure-activity relationships of ectonucleotidases with those of the P2-purinoceptor. European Journal of Pharmacology. 129: 217-24. PMID 3023103 DOI: 10.1016/0014-2999(86)90431-0  1
1985 Cusack NJ, Hourani SM, Welford LA. Characterisation of ADP receptors. Advances in Experimental Medicine and Biology. 192: 29-39. PMID 3010670  1
1985 Hourani SM, Welford LA, Cusack NJ. L-AMP-PCP, an ATP receptor agonist in guinea-pig bladder, is inactive on taenia coli. European Journal of Pharmacology. 108: 197-200. PMID 2984024 DOI: 10.1016/0014-2999(85)90726-5  1
1984 Cusack NJ, Hourani SM. Some pharmacological and biochemical interactions of the enantiomers of adenylyl 5'-(beta, gamma-methylene)-diphosphonate with the guinea-pig urinary bladder. British Journal of Pharmacology. 82: 155-9. PMID 6547360  1
1982 Cusack NJ, Hourani SM. Specific but noncompetitive inhibition by 2-alkylthio analogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. British Journal of Pharmacology. 75: 397-400. PMID 7186826  1
1982 Cusack NJ, Hourani SM. Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate. British Journal of Pharmacology. 77: 329-33. PMID 7139191  1
1982 Cusack NJ, Hourani SM. Differential inhibition by adenosine or by prostaglandin E1 of human platelet aggregation induced by adenosine 5'-O-(1-thiodiphosphate) and adenosine 5'-O-(2-thiodiphosphate). British Journal of Pharmacology. 75: 257-9. PMID 6892270  1
1982 Cusack NJ, Hourani SM. Adenosine 5-diphosphate antagonists and human platelets: no evidence that aggregation and inhibition of stimulated adenylate cyclase are mediated by different receptors. British Journal of Pharmacology. 76: 221-7. PMID 6282375  1
1981 Cusack NJ, Hourani SM. 5'-N-ethylcarboxamidoadenosine: a potent inhibitor of human platelet aggregation. British Journal of Pharmacology. 72: 443-7. PMID 7260485  1
1981 Cusack NJ, Hourani SM. Effects of RP and SP diastereoisomers of adenosine 5'-O-(1-thiodiphosphate) on human platelets. British Journal of Pharmacology. 73: 409-12. PMID 7236993  1
1981 Cusack NJ, Hourani SM. Partial agonist behaviour of adenosine 5'-O-(2-thiodiphosphate) on human platelets. British Journal of Pharmacology. 73: 405-8. PMID 7236992  1
1981 Cusack NJ, Hourani SMO. 5'-N-ethylcarboxamidoadenosine (NECA) is a potent stereospecific inhibitor of human platelet aggregation Thrombosis and Haemostasis. 46: No. 0451.  1
1981 Cusack NJ, Hourani SMO. Adenosine 5'-O-(2-thiodiphosphate) (ADP-β-S) is a partial agonist at the ADP receptor of human platelets Thrombosis and Haemostasis. 46: No. 0064.  1
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