Dale G. Deutsch - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 
Area:
Biochemistry, Cell Biology, Neuroscience Biology

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhou Y, Elmes MW, Sweeney J, Joseph O, Che J, Hsu HC, Li H, Deutsch DG, Ojima I, Kaczocha M, Rizzo RC. Identification of Fatty Acid Binding Protein 5 Inhibitors Through Similarity-based Screening. Biochemistry. PMID 31539229 DOI: 10.1021/acs.biochem.9b00625  1
2019 Kim J, Bogdan DM, Elmes MW, Awwa M, Yan S, Che J, Lee G, Deutsch DG, Rizzo RC, Kaczocha M, Ojima I. Incarvillateine produces antinociceptive and motor suppressive effects via adenosine receptor activation. Plos One. 14: e0218619. PMID 31237895 DOI: 10.1371/journal.pone.0218619  1
2019 Elmes MW, Prentis LE, McGoldrick LL, Giuliano CJ, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Studholme K, Deutsch DG, Rizzo RC, Glynn SE, Kaczocha M. FABP1 controls hepatic transport and biotransformation of Δ-THC. Scientific Reports. 9: 7588. PMID 31110286 DOI: 10.1038/s41598-019-44108-3  1
2018 Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, ... ... Deutsch DG, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. European Journal of Medicinal Chemistry. 154: 233-252. PMID 29803996 DOI: 10.1016/j.ejmech.2018.04.050  1
2018 Hamilton J, Koumas C, Clavin BH, Marion M, Figueiredo A, Gonzalez S, O'Rourke JR, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK. Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time. Behavioural Pharmacology. PMID 29570114 DOI: 10.1097/FBP.0000000000000402  1
2018 Haj-Dahmane S, Shen RY, Elmes MW, Studholme K, Kanjiya MP, Bogdan D, Thanos PK, Miyauchi JT, Tsirka SE, Deutsch DG, Kaczocha M. Fatty-acid-binding protein 5 controls retrograde endocannabinoid signaling at central glutamate synapses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531087 DOI: 10.1073/pnas.1721339115  1
2018 Hamilton J, Marion M, Figueiredo A, Clavin BH, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK. Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels. Synapse (New York, N.Y.). PMID 29457656 DOI: 10.1002/syn.22031  1
2017 Hsu HC, Tong S, Zhou Y, Elmes MW, Yan S, Kaczocha M, Deutsch DG, Rizzo RC, Ojima I, Li H. The antinociceptive agent SBFI-26 binds to anandamide transporters FABP5 and FABP7 at two different sites. Biochemistry. PMID 28632393 DOI: 10.1021/acs.biochem.7b00194  1
2017 Peng X, Studholme K, Kanjiya MP, Luk J, Bogdan D, Elmes MW, Carbonetti G, Tong S, Gary Teng YH, Rizzo RC, Li H, Deutsch DG, Ojima I, Rebecchi MJ, Puopolo M, et al. Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms. Molecular Pain. 13: 1744806917697007. PMID 28326944 DOI: 10.1177/1744806917697007  1
2016 Thanos PK, Clavin BH, Hamilton J, O'Rourke JR, Maher T, Koumas C, Miao E, Lankop J, Elhage A, Haj-Dahmane S, Deutsch D, Kaczocha M. Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26. Frontiers in Psychiatry. 7: 54. PMID 27092087 DOI: 10.3389/fpsyt.2016.00054  1
2015 Elmes MW, Kaczocha M, Berger WT, Leung K, Ralph BP, Wang L, Sweeney JM, Miyauchi JT, Tsirka SE, Ojima I, Deutsch DG. Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The Journal of Biological Chemistry. 290: 8711-21. PMID 25666611 DOI: 10.1074/jbc.M114.618447  1
2014 Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I. Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. Plos One. 9: e94200. PMID 24705380 DOI: 10.1371/journal.pone.0094200  1
2014 Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, Deutsch D, Li H. Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. Acta Crystallographica. Section D, Biological Crystallography. 70: 290-8. PMID 24531463 DOI: 10.1107/S1399004713026795  1
2013 Leung K, Elmes MW, Glaser ST, Deutsch DG, Kaczocha M. Role of FAAH-like anandamide transporter in anandamide inactivation. Plos One. 8: e79355. PMID 24223930 DOI: 10.1371/journal.pone.0079355  1
2013 Tsuboi K, Ikematsu N, Uyama T, Deutsch DG, Tokumura A, Ueda N. Biosynthetic pathways of bioactive N-acylethanolamines in brain. Cns & Neurological Disorders Drug Targets. 12: 7-16. PMID 23394527 DOI: 10.2174/1871527311312010005  1
2012 Berger WT, Ralph BP, Kaczocha M, Sun J, Balius TE, Rizzo RC, Haj-Dahmane S, Ojima I, Deutsch DG. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. Plos One. 7: e50968. PMID 23236415 DOI: 10.1371/journal.pone.0050968  1
2012 Kaczocha M, Lin Q, Nelson LD, McKinney MK, Cravatt BF, London E, Deutsch DG. Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. Acs Chemical Neuroscience. 3: 364-8. PMID 22860204 DOI: 10.1021/cn300001w  1
2012 Kaczocha M, Vivieca S, Sun J, Glaser ST, Deutsch DG. Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors. The Journal of Biological Chemistry. 287: 3415-24. PMID 22170058 DOI: 10.1074/jbc.M111.304907  1
2011 Tsuboi K, Okamoto Y, Ikematsu N, Inoue M, Shimizu Y, Uyama T, Wang J, Deutsch DG, Burns MP, Ulloa NM, Tokumura A, Ueda N. Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. Biochimica Et Biophysica Acta. 1811: 565-77. PMID 21801852 DOI: 10.1016/j.bbalip.2011.07.009  1
2011 Wellner N, Tsuboi K, Madsen AN, Holst B, Diep TA, Nakao M, Tokumura A, Burns MP, Deutsch DG, Ueda N, Hansen HS. Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice. Biochimica Et Biophysica Acta. 1811: 508-12. PMID 21723414 DOI: 10.1016/j.bbalip.2011.06.020  1
2011 Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG. Endocannabinoid tone versus constitutive activity of cannabinoid receptors. British Journal of Pharmacology. 163: 1329-43. PMID 21545414 DOI: 10.1111/j.1476-5381.2011.01364.x  1
2011 Izzo AA, Deutsch DG. Unique pathway for anandamide synthesis and liver regeneration. Proceedings of the National Academy of Sciences of the United States of America. 108: 6339-40. PMID 21490298 DOI: 10.1073/pnas.1103566108  1
2011 Shohami E, Cohen-Yeshurun A, Magid L, Algali M, Mechoulam R. Endocannabinoids and traumatic brain injury British Journal of Pharmacology. 163: 1402-1410. DOI: 10.1111/bph.2011.163  1
2010 Ulloa NM, Deutsch DG. Assessment of a spectrophotometric assay for monoacylglycerol lipase activity. The Aaps Journal. 12: 197-201. PMID 20186507 DOI: 10.1208/s12248-010-9180-6  1
2010 Kaczocha M, Glaser ST, Chae J, Brown DA, Deutsch DG. Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. The Journal of Biological Chemistry. 285: 2796-806. PMID 19926788 DOI: 10.1074/jbc.M109.058461  1
2009 Kaczocha M, Glaser ST, Deutsch DG. Identification of intracellular carriers for the endocannabinoid anandamide. Proceedings of the National Academy of Sciences of the United States of America. 106: 6375-80. PMID 19307565 DOI: 10.1073/pnas.0901515106  1
2006 Hermann A, Kaczocha M, Deutsch DG. 2-Arachidonoylglycerol (2-AG) membrane transport: history and outlook. The Aaps Journal. 8: E409-12. PMID 16808043 DOI: 10.1007/978-0-387-76678-2_43  1
2006 Kaczocha M, Hermann A, Glaser ST, Bojesen IN, Deutsch DG. Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. The Journal of Biological Chemistry. 281: 9066-75. PMID 16461355 DOI: 10.1074/jbc.M509721200  1
2005 Glaser ST, Deutsch DG, Studholme KM, Zimov S, Yazulla S. Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide. Visual Neuroscience. 22: 693-705. PMID 16469181 DOI: 10.1017/S0952523805226020  1
2005 Mechoulam R, Deutsch DG. Toward an anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America. 102: 17541-2. PMID 16314567 DOI: 10.1073/pnas.0508644102  1
2005 Deutsch DG. Design of on-target FAAH inhibitors. Chemistry & Biology. 12: 1157-8. PMID 16298293 DOI: 10.1016/j.chembiol.2005.11.001  1
2005 Glaser ST, Kaczocha M, Deutsch DG. Anandamide transport: a critical review. Life Sciences. 77: 1584-604. PMID 15979096 DOI: 10.1016/j.lfs.2005.05.007  1
2003 Glaser ST, Abumrad NA, Fatade F, Kaczocha M, Studholme KM, Deutsch DG. Evidence against the presence of an anandamide transporter. Proceedings of the National Academy of Sciences of the United States of America. 100: 4269-74. PMID 12655057 DOI: 10.1073/pnas.0730816100  1
2002 Deutsch DG, Ueda N, Yamamoto S. The fatty acid amide hydrolase (FAAH). Prostaglandins, Leukotrienes, and Essential Fatty Acids. 66: 201-10. PMID 12052036 DOI: 10.1054/plef.2001.0358  1
2001 Puffenbarger RA, Kapulina O, Howell JM, Deutsch DG. Characterization of the 5'-sequence of the mouse fatty acid amide hydrolase. Neuroscience Letters. 314: 21-4. PMID 11698137 DOI: 10.1016/S0304-3940(01)02274-1  1
2001 Day TA, Rakhshan F, Deutsch DG, Barker EL. Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. Molecular Pharmacology. 59: 1369-75. PMID 11353795  1
2001 Deutsch DG, Glaser ST, Howell JM, Kunz JS, Puffenbarger RA, Hillard CJ, Abumrad N. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. The Journal of Biological Chemistry. 276: 6967-73. PMID 11118429 DOI: 10.1074/jbc.M003161200  1
2000 Ueda N, Puffenbarger RA, Yamamoto S, Deutsch DG. The fatty acid amide hydrolase (FAAH). Chemistry and Physics of Lipids. 108: 107-21. PMID 11106785 DOI: 10.1016/S0009-3084(00)00190-0  1
2000 Stefano GB, Bilfinger TV, Rialas CM, Deutsch DG. 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 42: 317-22. PMID 10987990 DOI: 10.1006/phrs.2000.0702  1
2000 Martin BR, Beletskaya I, Patrick G, Jefferson R, Winckler R, Deutsch DG, Di Marzo V, Dasse O, Mahadevan A, Razdan RK. Cannabinoid properties of methylfluorophosphonate analogs. The Journal of Pharmacology and Experimental Therapeutics. 294: 1209-18. PMID 10945879  1
1999 Yazulla S, Studholme KM, McIntosh HH, Deutsch DG. Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina. The Journal of Comparative Neurology. 415: 80-90. PMID 10540359 DOI: 10.1002/(SICI)1096-9861(19991206)415:1<80::AID-CNE6>3.0.CO;2-H  1
1999 Omeir RL, Arreaza G, Deutsch DG. Identification of two serine residues involved in catalysis by fatty acid amide hydrolase. Biochemical and Biophysical Research Communications. 264: 316-20. PMID 10529361 DOI: 10.1006/bbrc.1999.1524  1
1999 Arreaza G, Deutsch DG. Deletion of a proline-rich region and a transmembrane domain in fatty acid amide hydrolase. Febs Letters. 454: 57-60. PMID 10413095 DOI: 10.1016/S0014-5793(99)00774-7  1
1999 Fimiani C, Mattocks D, Cavani F, Salzet M, Deutsch DG, Pryor S, Bilfinger TV, Stefano GB. Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. Cellular Signalling. 11: 189-93. PMID 10353693 DOI: 10.1016/S0898-6568(98)00060-6  1
1998 Tsou K, Nogueron MI, Muthian S, Sañudo-Pena MC, Hillard CJ, Deutsch DG, Walker JM. Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry. Neuroscience Letters. 254: 137-40. PMID 10214976 DOI: 10.1016/S0304-3940(98)00700-9  1
1998 Di Marzo V, Deutsch DG. Biochemistry of the endogenous ligands of cannabinoid receptors. Neurobiology of Disease. 5: 386-404. PMID 9974173 DOI: 10.1006/nbdi.1998.0214  1
1998 Bilfinger TV, Salzet M, Fimiani C, Deutsch DG, Tramu G, Stefano GB. Pharmacological evidence for anandamide amidase in human cardiac and vascular tissues. International Journal of Cardiology. 64: S15-22. PMID 9687088 DOI: 10.1016/S0167-5273(98)00031-X  1
1998 Stefano GB, Rialas CM, Deutsch DG, Salzet M. Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues. Brain Research. 793: 341-5. PMID 9630717 DOI: 10.1016/S0006-8993(98)00273-X  1
1997 Arreaza G, Devane WA, Omeir RL, Sajnani G, Kunz J, Cravatt BF, Deutsch DG. The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine. Neuroscience Letters. 234: 59-62. PMID 9347946 DOI: 10.1016/S0304-3940(97)00673-3  1
1997 Deutsch DG, Goligorsky MS, Schmid PC, Krebsbach RJ, Schmid HH, Das SK, Dey SK, Arreaza G, Thorup C, Stefano G, Moore LC. Production and physiological actions of anandamide in the vasculature of the rat kidney. The Journal of Clinical Investigation. 100: 1538-46. PMID 9294122 DOI: 10.1172/JCI119677  1
1997 Deutsch DG, Makriyannis A. Inhibitors of anandamide breakdown. Nida Research Monograph. 173: 65-84. PMID 9260184  1
1997 Deutsch DG, Lin S, Hill WA, Morse KL, Salehani D, Arreaza G, Omeir RL, Makriyannis A. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. Biochemical and Biophysical Research Communications. 231: 217-21. PMID 9070252 DOI: 10.1006/bbrc.1997.6072  1
1997 Deutsch DG, Omeir R, Arreaza G, Salehani D, Prestwich GD, Huang Z, Howlett A. Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase. Biochemical Pharmacology. 53: 255-60. PMID 9065728 DOI: 10.1016/S0006-2952(96)00830-1  1
1997 Thorup C, Goligorsky MS, Deutsch DG, Moore LC. Anandamide vasodilates rat juxtaglomerular afferent arterioles via enhanced nitric oxide (NO) production Faseb Journal. 11: A86.  1
1995 Omeir RL, Chin S, Hong Y, Ahern DG, Deutsch DG. Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase. Life Sciences. 56: 1999-2005. PMID 7776824 DOI: 10.1016/0024-3205(95)00181-5  1
1994 Koutek B, Prestwich GD, Howlett AC, Chin SA, Salehani D, Akhavan N, Deutsch DG. Inhibitors of arachidonoyl ethanolamide hydrolysis. The Journal of Biological Chemistry. 269: 22937-40. PMID 8083191  1
1993 Deutsch DG, Chin SA. Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochemical Pharmacology. 46: 791-6. PMID 8373432 DOI: 10.1016/0006-2952(93)90486-G  1
1993 Tombler ER, Deutsch DG. Spectrofluorometric assay for hybridization of oligodeoxynucleotides using ethidium dimer. Biotechniques. 15: 1060-4. PMID 8292339  1
1991 Deutsch DG, Tombler ER, March JE, Lo SH, Adesnik M. Potentiation of the inductive effect of phenobarbital on cytochrome P450 mRNAs by cannabidiol. Biochemical Pharmacology. 42: 2048-53. PMID 1741782 DOI: 10.1016/0006-2952(91)90608-8  1
1989 Duncan WP, Deutsch DG. The use of GC/IR/MS for high-confidence identification of drugs. Clinical Chemistry. 35: 1279-81. PMID 2758572  1
1988 Fand I, McNally WP, Koul O, Yonekura Y, Som P, Brill AB, Deutsch DG. Whole-body autoradiographic localization of [3H]phencyclidine and its metabolites in mice. Toxicology and Applied Pharmacology. 93: 421-32. PMID 3368921 DOI: 10.1016/0041-008X(88)90045-2  1
1986 Koul O, March JE, Sarma R, Griffiths C, Deutsch DG. Effect of phencyclidine on the metabolism of individual brain proteins. Journal of Neurochemistry. 46: 470-4. PMID 3941317 DOI: 10.1111/j.1471-4159.1986.tb12991.x  1
1986 Soo VA, Bergert RJ, Deutsch DG. Screening and quantification of hypnotic sedatives in serum by capillary gas chromatography with a nitrogen-phosphorus detector, and confirmation by capillary gas chromatography-mass spectrometry. Clinical Chemistry. 32: 325-8. PMID 2867839  1
1984 Deutsch DG, Koul O, Kersten RS. Phencyclidine and analogues: effects on brain protein synthesis. Journal of Neurochemistry. 42: 407-11. PMID 6693876 DOI: 10.1111/j.1471-4159.1984.tb02692.x  1
1983 Deutsch DG, Kineiko R, Garcia-Soto M. Effect of chronic phencyclidine administration upon blood biochemical profiles in rats. Substance and Alcohol Actions/Misuse. 4: 401-3. PMID 6687096  1
1980 Deutsch DG, Schechter N, Brecha N, Quitschke W, Schulman P, Cane M, Gazzaniga MS, Simpson MV. Analysis of protein levels and synthesis after learning in the split-brain pigeon. Brain Research. 198: 135-45. PMID 7407580 DOI: 10.1016/0006-8993(80)90349-2  1
1979 Schechter N, Francis A, Deutsch DG, Gazzaniga MS. Recovery of tectal nicotinic-cholinergic receptor sites during optic nerve degeneration in goldfish. Brain Research. 166: 57-64. PMID 421155 DOI: 10.1016/0006-8993(79)90649-8  1
1979 Deutsch DG, Sogard M. Observation of human low density lipoproteins in the STEM and FE-CTEM Micron (1969). 10: 25-28. DOI: 10.1016/0047-7206(79)90016-5  1
1978 Deutsch DG, Heinrikson RL, Foreman J, Scanu AM. Studies of the cyanogen bromide fragments of the apoprotein of human serum low density lipoproteins. Biochimica Et Biophysica Acta. 529: 342-50. PMID 207346 DOI: 10.1016/0005-2760(78)90077-2  1
1976 Deutsch DG. Effect of prolonged 100 degrees C heat treatment in sodium dodecyl sulfate upon peptide bond cleavage. Analytical Biochemistry. 71: 300-3. PMID 1275231 DOI: 10.1016/0003-2697(76)90040-3  1
1974 Chibber BA, Deutsch DG, Mertz ET. Affinity chromatography of plasminogen. Methods in Enzymology. 34: 424-32. PMID 4449462 DOI: 10.1016/S0076-6879(74)34051-7  1
1973 Deutsch DG, Fogleman DJ, Von Kaulla KN. Isolation of lipids from plasma by affinity chromatography. Biochemical and Biophysical Research Communications. 50: 758-64. PMID 4689076 DOI: 10.1016/0006-291X(73)91309-0  1
1972 Deutsch DG, Mertz ET. Activation of plasminogen with insoluble derivatives of urokinase. Journal of Medicine. 3: 224-30. PMID 4508564  1
1970 Deutsch DG, Mertz ET. Plasminogen: purification from human plasma by affinity chromatography. Science (New York, N.Y.). 170: 1095-6. PMID 5475635  1
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