Eric L. Barker - Publications

Affiliations: 
Purdue University, West Lafayette, IN, United States 
Area:
serotonin

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Barker EL. Editorial. Pharmacological Reviews. 68: 1-2. PMID 26589412 DOI: 10.1124/pr.115.012039  1
2013 Zohrabi-Kalantari V, Jarrahian A, Bissantz C, Bergstrom DE, Barker EL, Link A. 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 9: 881-8. PMID 23157226 DOI: 10.2174/1573406411309060013  1
2011 Sun L, Li HM, Seufferheld MJ, Walters KR, Margam VM, Jannasch A, Diaz N, Riley CP, Sun W, Li YF, Muir WM, Xie J, Wu J, Zhang F, Chen JY, ... Barker EL, et al. Systems-scale analysis reveals pathways involved in cellular response to methamphetamine. Plos One. 6: e18215. PMID 21533132 DOI: 10.1371/journal.pone.0018215  1
2010 Powers MS, Barrenha GD, Mlinac NS, Barker EL, Chester JA. Effects of the novel endocannabinoid uptake inhibitor, LY2183240, on fear-potentiated startle and alcohol-seeking behaviors in mice selectively bred for high alcohol preference. Psychopharmacology. 212: 571-83. PMID 20838777 DOI: 10.1007/s00213-010-1997-2  1
2010 Wenthur CJ, Rodríguez GJ, Kuntz CP, Barker EL. Conformational flexibility of transmembrane helix VII of the human serotonin transporter impacts ion dependence and transport. Biochemical Pharmacology. 80: 1418-26. PMID 20637736 DOI: 10.1016/j.bcp.2010.07.005  1
2010 Bardell TK, Barker EL. Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. Neurochemistry International. 57: 76-83. PMID 20466028 DOI: 10.1016/j.neuint.2010.05.002  1
2010 Placzek EA, Cooper BR, Placzek AT, Chester JA, Davisson VJ, Barker EL. Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide). Journal of Pharmaceutical and Biomedical Analysis. 53: 567-75. PMID 20417049 DOI: 10.1016/j.jpba.2010.03.035  1
2010 Torres-Altoro MI, Kuntz CP, Nichols DE, Barker EL. Structural analysis of the extracellular entrance to the serotonin transporter permeation pathway. The Journal of Biological Chemistry. 285: 15369-79. PMID 20304925 DOI: 10.1074/jbc.M109.088138  1
2009 Yates ML, Barker EL. Organized trafficking of anandamide and related lipids. Vitamins and Hormones. 81: 25-53. PMID 19647107 DOI: 10.1016/S0083-6729(09)81002-9  1
2009 Yates ML, Barker EL. Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. Molecular Pharmacology. 76: 11-7. PMID 19389920 DOI: 10.1124/mol.109.055251  1
2008 Placzek EA, Okamoto Y, Ueda N, Barker EL. Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. Journal of Neurochemistry. 107: 987-1000. PMID 18778304 DOI: 10.1111/j.1471-4159.2008.05659.x  1
2008 Placzek EA, Okamoto Y, Ueda N, Barker EL. Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. Neuropharmacology. 55: 1095-104. PMID 18760289 DOI: 10.1016/j.neuropharm.2008.07.047  1
2008 Torres-Altoro MI, White KJ, Rodríguez GJ, Nichols DE, Barker EL. Helix XI contributes to the entrance of the serotonin transporter permeation pathway. Protein Science : a Publication of the Protein Society. 17: 1761-70. PMID 18628241 DOI: 10.1110/ps.036749.108  1
2008 McFarland MJ, Bardell TK, Yates ML, Placzek EA, Barker EL. RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells. Molecular Pharmacology. 74: 101-8. PMID 18436710 DOI: 10.1124/mol.108.044834  1
2008 Walline CC, Nichols DE, Carroll FI, Barker EL. Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition. The Journal of Pharmacology and Experimental Therapeutics. 325: 791-800. PMID 18354055 DOI: 10.1124/jpet.108.136200  1
2007 Gallardo-Godoy A, Torres-Altoro MI, White KJ, Barker EL, Nichols DE. 1-Methylpyridinium-4-(4-phenylmethanethiosulfonate) iodide, MTS-MPP+, a novel scanning cysteine accessibility method (SCAM) reagent for monoamine transporter studies. Bioorganic & Medicinal Chemistry. 15: 305-11. PMID 17064910 DOI: 10.1016/j.bmc.2006.09.058  1
2006 White KJ, Kiser PD, Nichols DE, Barker EL. Engineered zinc-binding sites confirm proximity and orientation of transmembrane helices I and III in the human serotonin transporter. Protein Science : a Publication of the Protein Society. 15: 2411-22. PMID 17008722 DOI: 10.1110/ps.062386106  1
2006 McFarland MJ, Terebova EA, Barker EL. Detergent-resistant membrane microdomains in the disposition of the lipid signaling molecule anandamide. The Aaps Journal. 8: E95-100. PMID 16584138 DOI: 10.1208/aapsj080111  1
2005 White KJ, Walline CC, Barker EL. Serotonin transporters: implications for antidepressant drug development. The Aaps Journal. 7: E421-33. PMID 16353921 DOI: 10.1208/aapsj070242  1
2005 McFarland MJ, Barker EL. Lipid rafts: a nexus for endocannabinoid signaling? Life Sciences. 77: 1640-50. PMID 15978630 DOI: 10.1016/j.lfs.2005.05.010  1
2004 McFarland MJ, Barker EL. Anandamide transport. Pharmacology & Therapeutics. 104: 117-35. PMID 15518883 DOI: 10.1016/j.pharmthera.2004.07.008  1
2004 McFarland MJ, Porter AC, Rakhshan FR, Rawat DS, Gibbs RA, Barker EL. A role for caveolae/lipid rafts in the uptake and recycling of the endogenous cannabinoid anandamide. The Journal of Biological Chemistry. 279: 41991-7. PMID 15292270 DOI: 10.1074/jbc.M407250200  1
2004 Saldaña SN, Barker EL. Temperature and 3,4-methylenedioxymethamphetamine alter human serotonin transporter-mediated dopamine uptake. Neuroscience Letters. 354: 209-12. PMID 14700733 DOI: 10.1016/j.neulet.2003.10.032  1
2004 Jarrahian A, Watts VJ, Barker EL. D2 dopamine receptors modulate Galpha-subunit coupling of the CB1 cannabinoid receptor. The Journal of Pharmacology and Experimental Therapeutics. 308: 880-6. PMID 14634050 DOI: 10.1124/jpet.103.057620  1
2004 Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL. Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics. 308: 679-87. PMID 14593087 DOI: 10.1124/jpet.103.057836  1
2003 Roman DL, Walline CC, Rodriguez GJ, Barker EL. Interactions of antidepressants with the serotonin transporter: a contemporary molecular analysis. European Journal of Pharmacology. 479: 53-63. PMID 14612137 DOI: 10.1016/j.ejphar.2003.08.056  1
2003 Burdette JE, Liu J, Chen SN, Fabricant DS, Piersen CE, Barker EL, Pezzuto JM, Mesecar A, Van Breemen RB, Farnsworth NR, Bolton JL. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. Journal of Agricultural and Food Chemistry. 51: 5661-70. PMID 12952416 DOI: 10.1021/jf034264r  1
2003 Rodríguez GJ, Roman DL, White KJ, Nichols DE, Barker EL. Distinct recognition of substrates by the human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics. 306: 338-46. PMID 12682215 DOI: 10.1124/jpet.103.048751  1
2003 Kurrasch-Orbaugh DM, Watts VJ, Barker EL, Nichols DE. Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves. The Journal of Pharmacology and Experimental Therapeutics. 304: 229-37. PMID 12490596 DOI: 10.1124/jpet.102.042184  1
2001 Day TA, Rakhshan F, Deutsch DG, Barker EL. Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. Molecular Pharmacology. 59: 1369-75. PMID 11353795  1
2001 Adkins EM, Barker EL, Blakely RD. Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition. Molecular Pharmacology. 59: 514-23. PMID 11179447  1
2000 Blair JB, Kurrasch-Orbaugh D, Marona-Lewicka D, Cumbay MG, Watts VJ, Barker EL, Nichols DE. Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines. Journal of Medicinal Chemistry. 43: 4701-10. PMID 11101361 DOI: 10.1021/jm000339w  1
2000 Rakhshan F, Day TA, Blakely RD, Barker EL. Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells. The Journal of Pharmacology and Experimental Therapeutics. 292: 960-7. PMID 10688610  1
1999 Barker EL, Moore KR, Rakhshan F, Blakely RD. Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4705-17. PMID 10366604  1
1998 Barker EL, Blakely RD. Structural determinants of neurotransmitter transport using cross-species chimeras: studies on serotonin transporter. Methods in Enzymology. 296: 475-98. PMID 9779469 DOI: 10.1016/S0076-6879(98)96035-9  1
1998 Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB, Blakely RD. High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol. The Journal of Biological Chemistry. 273: 19459-68. PMID 9677366 DOI: 10.1074/jbc.273.31.19459  1
1998 Justice JB, Danek KS, Kable JW, Barker EL, Blakely RD. Voltammetric approaches to kinetics and mechanism of the norepinephrine transporter. Advances in Pharmacology (San Diego, Calif.). 42: 191-4. PMID 9327876 DOI: 10.1016/S1054-3589(08)60725-5  1
1996 Barker EL, Blakely RD. Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter. Molecular Pharmacology. 50: 957-65. PMID 8863842  1
1996 Canton H, Emeson RB, Barker EL, Backstrom JR, Lu JT, Chang MS, Sanders-Bush E. Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing. Molecular Pharmacology. 50: 799-807. PMID 8863824  1
1994 Demchyshyn LL, Pristupa ZB, Sugamori KS, Barker EL, Blakely RD, Wolfgang WJ, Forte MA, Niznik HB. Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 91: 5158-62. PMID 8197200  1
1994 Barker EL, Kimmel HL, Blakely RD. Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands. Molecular Pharmacology. 46: 799-807. PMID 7969065  1
1994 Barker EL, Westphal RS, Schmidt D, Sanders-Bush E. Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands. The Journal of Biological Chemistry. 269: 11687-90. PMID 7909313  1
1993 Barker EL, Sanders-Bush E. 5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Molecular Pharmacology. 44: 725-30. PMID 8232222  1
1991 Barker EL, Burris KD, Sanders-Bush E. Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain Research. 552: 330-2. PMID 1655172 DOI: 10.1016/0006-8993(91)90099-H  1
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