| Year |
Citation |
Score |
| 2017 |
Sealover NR, Felts B, Kuntz CP, Jarrard RE, Hockerman GH, Lamb PW, Barker EL, Henry LK. Corrigendum to "The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux" [Biochem. Pharmacol. 120 (2016) 46-55]. Biochemical Pharmacology. 147: 9. PMID 29195124 DOI: 10.1016/J.Bcp.2017.11.001 |
0.785 |
|
| 2016 |
Sealover NR, Felts B, Kuntz CP, Jarrard RE, Hockerman GH, Barker EL, Keith Henry L. The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux. Biochemical Pharmacology. PMID 27638414 DOI: 10.1016/J.Bcp.2016.09.006 |
0.808 |
|
| 2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, ... ... Barker EL, et al. The Concise Guide to PHARMACOLOGY 2013/14: overview. British Journal of Pharmacology. 170: 1449-58. PMID 24528237 DOI: 10.1111/Bph.12444 |
0.479 |
|
| 2010 |
Wenthur CJ, Rodríguez GJ, Kuntz CP, Barker EL. Conformational flexibility of transmembrane helix VII of the human serotonin transporter impacts ion dependence and transport. Biochemical Pharmacology. 80: 1418-26. PMID 20637736 DOI: 10.1016/J.Bcp.2010.07.005 |
0.652 |
|
| 2010 |
Placzek EA, Cooper BR, Placzek AT, Chester JA, Davisson VJ, Barker EL. Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide). Journal of Pharmaceutical and Biomedical Analysis. 53: 567-75. PMID 20417049 DOI: 10.1016/J.Jpba.2010.03.035 |
0.752 |
|
| 2010 |
Torres-Altoro MI, Kuntz CP, Nichols DE, Barker EL. Structural analysis of the extracellular entrance to the serotonin transporter permeation pathway. The Journal of Biological Chemistry. 285: 15369-79. PMID 20304925 DOI: 10.1074/jbc.M109.088138 |
0.495 |
|
| 2008 |
Placzek EA, Okamoto Y, Ueda N, Barker EL. Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. Journal of Neurochemistry. 107: 987-1000. PMID 18778304 DOI: 10.1111/J.1471-4159.2008.05659.X |
0.753 |
|
| 2008 |
Placzek EA, Okamoto Y, Ueda N, Barker EL. Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. Neuropharmacology. 55: 1095-104. PMID 18760289 DOI: 10.1016/J.Neuropharm.2008.07.047 |
0.741 |
|
| 2008 |
Torres-Altoro MI, White KJ, Rodríguez GJ, Nichols DE, Barker EL. Helix XI contributes to the entrance of the serotonin transporter permeation pathway. Protein Science : a Publication of the Protein Society. 17: 1761-70. PMID 18628241 DOI: 10.1110/Ps.036749.108 |
0.766 |
|
| 2008 |
McFarland MJ, Bardell TK, Yates ML, Placzek EA, Barker EL. RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells. Molecular Pharmacology. 74: 101-8. PMID 18436710 DOI: 10.1124/Mol.108.044834 |
0.749 |
|
| 2008 |
Walline CC, Nichols DE, Carroll FI, Barker EL. Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition. The Journal of Pharmacology and Experimental Therapeutics. 325: 791-800. PMID 18354055 DOI: 10.1124/jpet.108.136200 |
0.779 |
|
| 2007 |
Gallardo-Godoy A, Torres-Altoro MI, White KJ, Barker EL, Nichols DE. 1-Methylpyridinium-4-(4-phenylmethanethiosulfonate) iodide, MTS-MPP+, a novel scanning cysteine accessibility method (SCAM) reagent for monoamine transporter studies. Bioorganic & Medicinal Chemistry. 15: 305-11. PMID 17064910 DOI: 10.1016/J.Bmc.2006.09.058 |
0.705 |
|
| 2006 |
White KJ, Kiser PD, Nichols DE, Barker EL. Engineered zinc-binding sites confirm proximity and orientation of transmembrane helices I and III in the human serotonin transporter. Protein Science : a Publication of the Protein Society. 15: 2411-22. PMID 17008722 DOI: 10.1110/Ps.062386106 |
0.7 |
|
| 2006 |
McFarland MJ, Terebova EA, Barker EL. Detergent-resistant membrane microdomains in the disposition of the lipid signaling molecule anandamide. The Aaps Journal. 8: E95-100. PMID 16584138 DOI: 10.1208/Aapsj080111 |
0.598 |
|
| 2005 |
White KJ, Walline CC, Barker EL. Serotonin transporters: implications for antidepressant drug development. The Aaps Journal. 7: E421-33. PMID 16353921 DOI: 10.1208/Aapsj070242 |
0.763 |
|
| 2005 |
McFarland MJ, Barker EL. Lipid rafts: a nexus for endocannabinoid signaling? Life Sciences. 77: 1640-50. PMID 15978630 DOI: 10.1016/J.Lfs.2005.05.010 |
0.585 |
|
| 2004 |
McFarland MJ, Barker EL. Anandamide transport. Pharmacology & Therapeutics. 104: 117-35. PMID 15518883 DOI: 10.1016/j.pharmthera.2004.07.008 |
0.67 |
|
| 2004 |
McFarland MJ, Porter AC, Rakhshan FR, Rawat DS, Gibbs RA, Barker EL. A role for caveolae/lipid rafts in the uptake and recycling of the endogenous cannabinoid anandamide. The Journal of Biological Chemistry. 279: 41991-7. PMID 15292270 DOI: 10.1074/Jbc.M407250200 |
0.679 |
|
| 2004 |
Saldaña SN, Barker EL. Temperature and 3,4-methylenedioxymethamphetamine alter human serotonin transporter-mediated dopamine uptake. Neuroscience Letters. 354: 209-12. PMID 14700733 DOI: 10.1016/j.neulet.2003.10.032 |
0.375 |
|
| 2004 |
Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL. Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics. 308: 679-87. PMID 14593087 DOI: 10.1124/Jpet.103.057836 |
0.72 |
|
| 2003 |
Roman DL, Walline CC, Rodriguez GJ, Barker EL. Interactions of antidepressants with the serotonin transporter: a contemporary molecular analysis. European Journal of Pharmacology. 479: 53-63. PMID 14612137 DOI: 10.1016/J.Ejphar.2003.08.056 |
0.778 |
|
| 2003 |
Rodríguez GJ, Roman DL, White KJ, Nichols DE, Barker EL. Distinct recognition of substrates by the human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics. 306: 338-46. PMID 12682215 DOI: 10.1124/Jpet.103.048751 |
0.809 |
|
| 2003 |
Kurrasch-Orbaugh DM, Watts VJ, Barker EL, Nichols DE. Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves. The Journal of Pharmacology and Experimental Therapeutics. 304: 229-37. PMID 12490596 DOI: 10.1124/Jpet.102.042184 |
0.369 |
|
| 2001 |
Day TA, Rakhshan F, Deutsch DG, Barker EL. Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. Molecular Pharmacology. 59: 1369-75. PMID 11353795 DOI: 10.1124/Mol.59.6.1369 |
0.473 |
|
| 2001 |
Adkins EM, Barker EL, Blakely RD. Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition. Molecular Pharmacology. 59: 514-23. PMID 11179447 DOI: 10.1124/Mol.59.3.514 |
0.805 |
|
| 2000 |
Blair JB, Kurrasch-Orbaugh D, Marona-Lewicka D, Cumbay MG, Watts VJ, Barker EL, Nichols DE. Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines. Journal of Medicinal Chemistry. 43: 4701-10. PMID 11101361 DOI: 10.1021/Jm000339W |
0.374 |
|
| 2000 |
Rakhshan F, Day TA, Blakely RD, Barker EL. Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells. The Journal of Pharmacology and Experimental Therapeutics. 292: 960-7. PMID 10688610 |
0.579 |
|
| 1999 |
Barker EL, Moore KR, Rakhshan F, Blakely RD. Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4705-17. PMID 10366604 DOI: 10.1523/Jneurosci.19-12-04705.1999 |
0.645 |
|
| 1998 |
Barker EL, Blakely RD. Structural determinants of neurotransmitter transport using cross-species chimeras: studies on serotonin transporter. Methods in Enzymology. 296: 475-98. PMID 9779469 DOI: 10.1016/S0076-6879(98)96035-9 |
0.655 |
|
| 1998 |
Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB, Blakely RD. High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol. The Journal of Biological Chemistry. 273: 19459-68. PMID 9677366 DOI: 10.1074/Jbc.273.31.19459 |
0.81 |
|
| 1998 |
Justice JB, Danek KS, Kable JW, Barker EL, Blakely RD. Voltammetric approaches to kinetics and mechanism of the norepinephrine transporter. Advances in Pharmacology (San Diego, Calif.). 42: 191-4. PMID 9327876 DOI: 10.1016/S1054-3589(08)60725-5 |
0.587 |
|
| 1996 |
Barker EL, Blakely RD. Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter. Molecular Pharmacology. 50: 957-65. PMID 8863842 |
0.585 |
|
| 1994 |
Demchyshyn LL, Pristupa ZB, Sugamori KS, Barker EL, Blakely RD, Wolfgang WJ, Forte MA, Niznik HB. Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 91: 5158-62. PMID 8197200 DOI: 10.1073/Pnas.91.11.5158 |
0.669 |
|
| 1994 |
Barker EL, Kimmel HL, Blakely RD. Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands. Molecular Pharmacology. 46: 799-807. PMID 7969065 |
0.594 |
|
| 1991 |
Barker EL, Burris KD, Sanders-Bush E. Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain Research. 552: 330-2. PMID 1655172 DOI: 10.1016/0006-8993(91)90099-H |
0.422 |
|
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