Year |
Citation |
Score |
2018 |
Ishii DN. Why clinical trials that reduce glucose levels fail to prevent complications in diabetic patients: Tests support an alternative hypothesis for pathogenesis Journal of Diabetes & Metabolism. 9. DOI: 10.4172/2155-6156-c4-086 |
0.381 |
|
2017 |
Ishii DN. WHY CLINICAL TRIALS SHOW THAT STRICT GLUCOSE REGULATION DOES NOT PREVENT DIABETIC COMPLICATIONS IN T2D: EVIDENCE SUPPORTING AN ALTERNATIVE HYPOTHESIS FOR PATHOGENESIS Pancreatic Disorders and Therapy. 7. DOI: 10.4172/2165-7092-C1-007 |
0.391 |
|
2016 |
Ishii DN. Insulin-like growth factors (IGFs) prevent diabetic peripheral neuropathy despite unabated hyperglycemia: Why hyperglycemia interventions fail in clinical trials? Journal of Diabetes & Metabolism. 7. DOI: 10.4172/2155-6156.C1.047 |
0.515 |
|
2012 |
Serbedžija P, Ishii DN. Insulin and insulin-like growth factor prevent brain atrophy and cognitive impairment in diabetic rats. Indian Journal of Endocrinology and Metabolism. 16: S601-10. PMID 23565496 DOI: 10.4103/2230-8210.105578 |
0.822 |
|
2012 |
Ishii D, Serbedzija P. P3-042: Pathogenesis of brain degeneration and cognitive impairment in diabetes: Implications for Alzheimer's disease Alzheimer's & Dementia. 8: P470-P470. DOI: 10.1016/j.jalz.2012.05.1260 |
0.772 |
|
2009 |
Serbedzija P, Madl JE, Ishii DN. Insulin and IGF-I prevent brain atrophy and DNA loss in diabetes. Brain Research. 1303: 179-94. PMID 19781531 DOI: 10.1016/j.brainres.2009.09.063 |
0.815 |
|
2006 |
Seigel GM, Lupien SB, Campbell LM, Ishii DN. Systemic IGF-I treatment inhibits cell death in diabetic rat retina. Journal of Diabetes and Its Complications. 20: 196-204. PMID 16632241 DOI: 10.1016/J.Jdiacomp.2005.06.007 |
0.766 |
|
2006 |
Lupien SB, Bluhm EJ, Ishii DN. Effect of IGF-I on DNA, RNA, and protein loss associated with brain atrophy and impaired learning in diabetic rats. Neurobiology of Disease. 21: 487-95. PMID 16181784 DOI: 10.1016/J.Nbd.2005.08.008 |
0.775 |
|
2003 |
Ishii DN, Lupien SB. Insulin-like growth factor replacement therapy for diabetic neuropathy: experimental basis. Experimental Diabesity Research. 4: 257-69. PMID 14668048 DOI: 10.1155/Edr.2003.257 |
0.781 |
|
2003 |
Lupien SB, Bluhm EJ, Ishii DN. Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. Journal of Neuroscience Research. 74: 512-23. PMID 14598295 DOI: 10.1002/Jnr.10791 |
0.784 |
|
2003 |
Kummer A, Pulford BE, Ishii DN, Seigel GM. Des(1-3)IGF-1 treatment normalizes type 1 IGF receptor and phospho-Akt (Thr 308) immunoreactivity in predegenerative retina of diabetic rats. International Journal of Experimental Diabesity Research. 4: 45-57. PMID 12745670 DOI: 10.1080/15438600303729 |
0.558 |
|
2002 |
Ferreira LD, Huey PU, Pulford BE, Ishii DN, Eckel RH. Sciatic nerve lipoprotein lipase is reduced in streptozotocin-induced diabetes and corrected by insulin. Endocrinology. 143: 1213-7. PMID 11897675 DOI: 10.1210/Endo.143.4.8723 |
0.506 |
|
2001 |
Pulford BE, Ishii DN. Uptake of Circulating Insulin-Like Growth Factors (IGFs) into Cerebrospinal Fluid Appears to Be Independent of the IGF Receptors as Well as IGF-Binding Proteins* * This work was supported by Centers for Disease Control and Prevention Grant R49/CCR811509. Endocrinology. 142: 213-220. PMID 28201223 DOI: 10.1210/endo.142.1.7894 |
0.318 |
|
2001 |
Nishiyama A, Ishii DN, Backx PH, Pulford BE, Birks BR, Tamkun MM. Altered K(+) channel gene expression in diabetic rat ventricle: isoform switching between Kv4.2 and Kv1.4. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1800-7. PMID 11557574 DOI: 10.1152/Ajpheart.2001.281.4.H1800 |
0.483 |
|
2001 |
Pulford BE, Ishii DN. Uptake of circulating insulin-like growth factors (IGFs) into cerebrospinal fluid appears to be independent of the IGF receptors as well as IGF-binding proteins. Endocrinology. 142: 213-20. PMID 11145584 DOI: 10.1210/Endo.142.1.7894 |
0.344 |
|
2000 |
Armstrong CS, Wuarin L, Ishii DN. Uptake of circulating insulin-like growth factor-I into the cerebrospinal fluid of normal and diabetic rats and normalization of IGF-II mRNA content in diabetic rat brain. Journal of Neuroscience Research. 59: 649-60. PMID 10686593 DOI: 10.1002/(SICI)1097-4547(20000301)59:5<649::AID-JNR8>3.0.CO;2-W |
0.512 |
|
1996 |
Wuarin L, Namdev R, Burns JG, Fei ZJ, Ishii DN. Brain insulin-like growth factor-II mRNA content is reduced in insulin-dependent and non-insulin-dependent diabetes mellitus. Journal of Neurochemistry. 67: 742-51. PMID 8764603 DOI: 10.1046/J.1471-4159.1996.67020742.X |
0.621 |
|
1996 |
Zhuang HX, Snyder CK, Pu SF, Ishii DN. Insulin-like growth factors reverse or arrest diabetic neuropathy: effects on hyperalgesia and impaired nerve regeneration in rats. Experimental Neurology. 140: 198-205. PMID 8690062 DOI: 10.1006/exnr.1996.0129 |
0.648 |
|
1995 |
Wuarin L, Guertin DM, Ishii DN. Early reduction in insulin-like growth factor gene expression in diabetic nerve. Experimental Neurology. 130: 106-14. PMID 7821385 DOI: 10.1006/exnr.1994.1189 |
0.552 |
|
1995 |
Ishii DN, Lupien SB. Insulin-like growth factors protect against diabetic neuropathy: effects on sensory nerve regeneration in rats. Journal of Neuroscience Research. 40: 138-44. PMID 7714922 DOI: 10.1002/Jnr.490400116 |
0.761 |
|
1995 |
Ishii DN. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy. Brain Research. Brain Research Reviews. 20: 47-67. PMID 7711767 DOI: 10.1016/0165-0173(94)00005-A |
0.609 |
|
1993 |
Ishii DN. Insulin and related neurotrophic factors in diabetic neuropathy. Diabetic Medicine : a Journal of the British Diabetic Association. 14S-15S. PMID 8334835 DOI: 10.1111/j.1464-5491.1993.tb00190.x |
0.577 |
|
1993 |
Glazner GW, Lupien S, Miller JA, Ishii DN. Insulin-like growth factor II increases the rate of sciatic nerve regeneration in rats Neuroscience. 54: 791-797. PMID 8332262 DOI: 10.1016/0306-4522(93)90248-E |
0.362 |
|
1993 |
Ishii DN, Glazner GW, Whalen LR. Regulation of peripheral nerve regeneration by insulin-like growth factors. Annals of the New York Academy of Sciences. 692: 172-82. PMID 8215021 DOI: 10.1111/j.1749-6632.1993.tb26215.x |
0.316 |
|
1992 |
Ishii DN, Wang C, Li Y. Second messengers mediating gene expression essential to neurite formation directed by insulin and insulin-like growth factors. Advances in Experimental Medicine and Biology. 293: 361-78. PMID 1767737 DOI: 10.1007/978-1-4684-5949-4_32 |
0.345 |
|
1992 |
Wang C, Li Y, Wible B, Angelides KJ, Ishii DN. Effects of insulin and insulin-like growth factors on neurofilament mRNA and tubulin mRNA content in human neuroblastoma SH-SY5Y cells. Brain Research. Molecular Brain Research. 13: 289-300. PMID 1320719 DOI: 10.1016/0169-328X(92)90212-T |
0.322 |
|
1989 |
Fernyhough P, Mill JF, Roberts JL, Ishii DN. Stabilization of tubulin mRNAs by insulin and insulin-like growth factor I during neurite formation. Brain Research. Molecular Brain Research. 6: 109-20. PMID 2693875 DOI: 10.1016/0169-328X(89)90044-2 |
0.301 |
|
1988 |
Recio-Pinto E, Ishii DN. Insulin and related growth factors: effects on the nervous system and mechanism for neurite growth and regeneration. Neurochemistry International. 12: 397-414. PMID 20501244 DOI: 10.1016/0197-0186(88)90021-6 |
0.335 |
|
1988 |
Recio-Pinto E, Ishii DN. Insulin and insulinlike growth factor receptors regulating neurite formation in cultured human neuroblastoma cells. Journal of Neuroscience Research. 19: 312-20. PMID 3288762 DOI: 10.1002/jnr.490190306 |
0.342 |
|
1986 |
Recio-Pinto E, Rechler MM, Ishii DN. Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1211-9. PMID 3519887 |
0.34 |
|
1985 |
Mill JF, Chao MV, Ishii DN. Insulin, insulin-like growth factor II, and nerve growth factor effects on tubulin mRNA levels and neurite formation. Proceedings of the National Academy of Sciences of the United States of America. 82: 7126-30. PMID 3901011 DOI: 10.1073/Pnas.82.20.7126 |
0.354 |
|
1984 |
Recio-Pinto E, Ishii DN. Effects of insulin, insulin-like growth factor-II and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells. Brain Research. 302: 323-34. PMID 6329460 DOI: 10.1016/0006-8993(84)90246-4 |
0.359 |
|
1984 |
Recio-Pinto E, Lang FF, Ishii DN. Insulin and insulin-like growth factor II permit nerve growth factor binding and the neurite formation response in cultured human neuroblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2562-6. PMID 6326132 DOI: 10.1073/Pnas.81.8.2562 |
0.374 |
|
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