Boris D. Heifets, M.D., Ph.D. - Publications

Affiliations: 
Anesthesiology Stanford University, Palo Alto, CA 
Area:
synaptic transmission, electrophysiology

26/59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pomrenze MB, Vaillancourt S, Llorach P, Rijsketic DR, Casey AB, Gregory N, Salgado JS, Malenka RC, Heifets BD. Opioid receptor expressing neurons of the central amygdala gate behavioral effects of ketamine in mice. Biorxiv : the Preprint Server For Biology. PMID 38496451 DOI: 10.1101/2024.03.03.583196  0.777
2023 Hack LM, Zhang X, Heifets BD, Suppes T, van Roessel PJ, Yesavage JA, Gray NJ, Hilton R, Bertrand C, Rodriguez CI, Deisseroth K, Knutson B, Williams LM. Ketamine's acute effects on negative brain states are mediated through distinct altered states of consciousness in humans. Nature Communications. 14: 6631. PMID 37857620 DOI: 10.1038/s41467-023-42141-5  0.444
2023 Barbosa DAN, Gattas S, Salgado JS, Kuijper FM, Wang AR, Huang Y, Kakusa B, Leuze C, Luczak A, Rapp P, Malenka RC, Hermes D, Miller KJ, Heifets BD, Bohon C, et al. An orexigenic subnetwork within the human hippocampus. Nature. PMID 37648849 DOI: 10.1038/s41586-023-06459-w  0.478
2023 Rijsketic DR, Casey AB, Barbosa DAN, Zhang X, Hietamies TM, Ramirez-Ovalle G, Pomrenze MB, Halpern CH, Williams LM, Malenka RC, Heifets BD. UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37248402 DOI: 10.1038/s41386-023-01613-4  0.771
2023 Rijsketic DR, Casey AB, Barbosa DAN, Zhang X, Hietamies TM, Ramirez-Ovalle G, Pomrenze M, Halpern CH, Williams LM, Malenka RC, Heifets BD. UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice. Biorxiv : the Preprint Server For Biology. PMID 36865251 DOI: 10.1101/2023.02.19.528997  0.763
2022 Pomrenze MB, Cardozo Pinto DF, Neumann PA, Llorach P, Tucciarone JM, Morishita W, Eshel N, Heifets BD, Malenka RC. Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal. Neuron. PMID 36202097 DOI: 10.1016/j.neuron.2022.09.024  0.779
2022 Wu H, Kakusa B, Neuner S, Christoffel DJ, Heifets BD, Malenka RC, Halpern CH. Local accumbens in vivo imaging during deep brain stimulation reveals a strategy-dependent amelioration of hedonic feeding. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 34921100 DOI: 10.1073/pnas.2109269118  0.736
2021 Wu X, Morishita W, Beier KT, Heifets BD, Malenka RC. 5-HT modulation of a medial septal circuit tunes social memory stability. Nature. 599: 96-101. PMID 34616037 DOI: 10.1038/s41586-021-03956-8  0.475
2021 Walsh JJ, Llorach P, Cardozo Pinto DF, Wenderski W, Christoffel DJ, Salgado JS, Heifets BD, Crabtree GR, Malenka RC. Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34239048 DOI: 10.1038/s41386-021-01091-6  0.77
2021 Christoffel DJ, Walsh JJ, Hoerbelt P, Heifets BD, Llorach P, Lopez RC, Ramakrishnan C, Deisseroth K, Malenka RC. Selective filtering of excitatory inputs to nucleus accumbens by dopamine and serotonin. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34103400 DOI: 10.1073/pnas.2106648118  0.751
2021 Christoffel DJ, Walsh JJ, Heifets BD, Hoerbelt P, Neuner S, Sun G, Ravikumar VK, Wu H, Halpern CH, Malenka RC. Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nature Communications. 12: 2135. PMID 33837200 DOI: 10.1038/s41467-021-22430-7  0.748
2020 Heifets BD, Malenka RC. Better living through chemistry: MDMA's prosocial mechanism as a starting point for improved therapeutics. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32792684 DOI: 10.1038/s41386-020-00803-8  0.458
2020 Steinberg EE, Gore F, Heifets BD, Taylor MD, Norville ZC, Beier KT, Földy C, Lerner TN, Luo L, Deisseroth K, Malenka RC. Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning. Neuron. PMID 32294466 DOI: 10.1016/J.Neuron.2020.03.016  0.778
2019 Heifets BD, Salgado JS, Taylor MD, Hoerbelt P, Cardozo Pinto DF, Steinberg EE, Walsh JJ, Sze JY, Malenka RC. Distinct neural mechanisms for the prosocial and rewarding properties of MDMA. Science Translational Medicine. 11. PMID 31826983 DOI: 10.1126/Scitranslmed.Aaw6435  0.76
2019 Heifets BD, Malenka RC. Disruptive Psychopharmacology. Jama Psychiatry. PMID 31241740 DOI: 10.1001/jamapsychiatry.2019.1145  0.416
2018 Walsh JJ, Christoffel DJ, Heifets BD, Ben-Dor GA, Selimbeyoglu A, Hung LW, Deisseroth K, Malenka RC. 5-HT release in nucleus accumbens rescues social deficits in mouse autism model. Nature. PMID 30089910 DOI: 10.1038/S41586-018-0416-4  0.772
2018 Hoerbelt P, Heifets BD. Native System and Cultured Cell Electrophysiology for Investigating Anesthetic Mechanisms. Methods in Enzymology. 602: 301-338. PMID 29588037 DOI: 10.1016/Bs.Mie.2018.01.012  0.762
2018 Beier K, Kim C, Hoerbelt P, Hung LW, Heifets B, DeLoach K, Mosca T, Neuner S, Deisseroth K, Luo L, Malenka R. T273. A Critical Role for the Globus Pallidus in Cocaine-Triggered Plasticity Revealed Byrabies Activity Screen Biological Psychiatry. 83: S235-S236. DOI: 10.1016/J.Biopsych.2018.02.610  0.733
2017 Beier KT, Kim CK, Hoerbelt P, Hung LW, Heifets BD, DeLoach KE, Mosca TJ, Neuner S, Deisseroth K, Luo L, Malenka RC. Rabies screen reveals GPe control of cocaine-triggered plasticity. Nature. PMID 28902833 DOI: 10.1038/Nature23888  0.766
2016 Heifets BD, Malenka RC. MDMA as a Probe and Treatment for Social Behaviors. Cell. 166: 269-72. PMID 27419864 DOI: 10.1016/j.cell.2016.06.045  0.502
2014 Schwartz N, Temkin P, Jurado S, Lim BK, Heifets BD, Polepalli JS, Malenka RC. Chronic pain. Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens. Science (New York, N.Y.). 345: 535-42. PMID 25082697 DOI: 10.1126/Science.1253994  0.703
2009 Heifets BD, Castillo PE. Endocannabinoid signaling and long-term synaptic plasticity. Annual Review of Physiology. 71: 283-306. PMID 19575681 DOI: 10.1146/annurev.physiol.010908.163149  0.506
2008 Heifets BD, Chevaleyre V, Castillo PE. Interneuron activity controls endocannabinoid-mediated presynaptic plasticity through calcineurin. Proceedings of the National Academy of Sciences of the United States of America. 105: 10250-5. PMID 18632563 DOI: 10.1073/pnas.0711880105  0.503
2007 Chevaleyre V, Heifets BD, Kaeser PS, Südhof TC, Purpura DP, Castillo PE. Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alpha. Neuron. 54: 801-12. PMID 17553427 DOI: 10.1016/j.neuron.2007.05.020  0.501
2007 Chevaleyre V, Heifets BD, Kaeser PS, Südhof TC, Castillo PE. Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α (DOI:10.1016/j.neuron.2007.05.020) Neuron. 55: 169. DOI: 10.1016/j.neuron.2007.06.024  0.494
2002 Gold SJ, Heifets BD, Pudiak CM, Potts BW, Nestler EJ. Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures. Journal of Neurochemistry. 82: 828-38. PMID 12358788 DOI: 10.1046/J.1471-4159.2002.01002.X  0.416
Low-probability matches (unlikely to be authored by this person)
2019 Cayla NS, Dagne BA, Wu Y, Lu Y, Rodriguez L, Davies DL, Gross ER, Heifets BD, Davies MF, MacIver MB, Bertaccini EJ. A newly developed anesthetic based on a unique chemical core. Proceedings of the National Academy of Sciences of the United States of America. PMID 31308218 DOI: 10.1073/Pnas.1822076116  0.296
2019 Williams NR, Heifets BD, Bentzley BS, Blasey C, Sudheimer KD, Hawkins J, Lyons DM, Schatzberg AF. Attenuation of antidepressant and antisuicidal effects of ketamine by opioid receptor antagonism. Molecular Psychiatry. PMID 31467392 DOI: 10.1038/S41380-019-0503-4  0.29
2018 Williams NR, Heifets BD, Blasey C, Sudheimer K, Pannu J, Pankow H, Hawkins J, Birnbaum J, Lyons DM, Rodriguez CI, Schatzberg AF. Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism. The American Journal of Psychiatry. appiajp201818020138. PMID 30153752 DOI: 10.1176/Appi.Ajp.2018.18020138  0.289
2013 Heifets BD, Smith SM, Leong MS. Acute cardiovascular toxicity of low-dose intrathecal ziconotide. Pain Medicine (Malden, Mass.). 14: 1807-9. PMID 23855951 DOI: 10.1111/pme.12196  0.28
2019 Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF. Interpreting Ketamine's Opioid Receptor Dependent Effect: Response to Sanacora. The American Journal of Psychiatry. 176: 249-250. PMID 30818991 DOI: 10.1176/Appi.Ajp.2018.18091061R  0.275
2019 Heifets BD, Williams NR, Bentzley BS, Schatzberg AF. Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect. Jama Psychiatry. PMID 31042274 DOI: 10.1001/Jamapsychiatry.2019.0766  0.271
2019 Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF. Rigorous Translational Models Are Key to Studying Ketamine's Antidepressant Mechanism: Response to Wang and Kaplin. The American Journal of Psychiatry. 176: 412. PMID 31039633 DOI: 10.1176/Appi.Ajp.2019.19010044R  0.246
2019 Williams N, Heifets B, Bentzley B, Blasey C, Sudheimer K, Lyons D, Schatzberg A. O19. Attenuation of Anti-Suicidal Effects of Ketamine by Opioid Receptor Antagonism Biological Psychiatry. 85: S113. DOI: 10.1016/J.Biopsych.2019.03.284  0.246
2002 Woodruff-Pak DS, Green JT, Pak JT, Heifets B, Pak MH. The effect of scopolamine in older rabbits tested in the 750 ms delay eyeblink classical conditioning procedure. Integrative Physiological and Behavioral Science : the Official Journal of the Pavlovian Society. 37: 103-13. PMID 12186305 DOI: 10.1007/Bf02688823  0.224
2019 Heifets BD, Williams NR, Blasey C, Sudheimer K, Rodriguez CI, Schatzberg AF. Target Population, Dose, and Timing Considerations for Understanding Naltrexone's Subjective Effect: Response to Amiaz. The American Journal of Psychiatry. 176: 251-252. PMID 30818989 DOI: 10.1176/Appi.Ajp.2018.18111231R  0.215
2023 Heifets BD, Olson DE. Therapeutic mechanisms of psychedelics and entactogens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37488282 DOI: 10.1038/s41386-023-01666-5  0.209
1999 Witkin JM, Gasior M, Heifets B, Tortella FC. Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine. The Journal of Pharmacology and Experimental Therapeutics. 289: 703-11. PMID 10215643  0.196
2018 Heifets BD, Tanaka P, Burbridge MA. Fluid management concepts for severe neurological illness: an overview. Current Opinion in Anaesthesiology. PMID 30015638 DOI: 10.1097/ACO.0000000000000629  0.189
2001 Mendelson J, Herbst E, Heifets B, Baggott M, Jacob P, Everhart ET, Jones RT. The effect of route of cocaine administration on cocaethylene formation Clinical Pharmacology and Therapeutics. 69: P29.  0.183
2000 Baggott M, Heifets B, Jones RT, Mendelson J, Sferios E, Zehnder J. Chemical analysis of ecstasy pills. Jama. 284: 2190. PMID 11056589 DOI: 10.1001/Jama.284.17.2190  0.182
2020 De Gregorio D, Aguilar-Valles A, Preller KH, Heifets BD, Hibicke M, Mitchell J, Gobbi G. Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33257322 DOI: 10.1523/JNEUROSCI.1659-20.2020  0.136
2024 Hack LM, Sikka P, Zhou K, Kawai M, Chow HS, Heifets B. Reduction in Trauma-Related Symptoms After Anesthetic-Induced Intra-Operative Dreaming. The American Journal of Psychiatry. appiajp20230698. PMID 38476046 DOI: 10.1176/appi.ajp.20230698  0.12
2024 Szigeti B, Heifets BD. Expectancy Effects in Psychedelic Trials. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 38387698 DOI: 10.1016/j.bpsc.2024.02.004  0.12
2023 Lii TR, Smith AE, Flohr JR, Okada RL, Nyongesa CA, Cianfichi LJ, Hack LM, Schatzberg AF, Heifets BD. Randomized trial of ketamine masked by surgical anesthesia in patients with depression. Nature Mental Health. 1: 876-886. PMID 38188539 DOI: 10.1038/s44220-023-00140-x  0.089
2002 Pak JT, Green JT, Heifets B, Pak MH, Woodruff-Pak DS. Nefiracetam ameliorates associative learning impairment in the scopolamine-injected older rabbit Medical Science Monitor. 8: BR105-BR112. PMID 11951055  0.088
2023 Hietamies TM, McInnes LA, Klise AJ, Worley MJ, Qian JJ, Williams LM, Heifets BD, Levine SP. The effects of ketamine on symptoms of depression and anxiety in real-world care settings: A retrospective controlled analysis. Journal of Affective Disorders. PMID 37201900 DOI: 10.1016/j.jad.2023.04.141  0.081
2022 Aday JS, Heifets BD, Pratscher SD, Bradley E, Rosen R, Woolley JD. Great Expectations: recommendations for improving the methodological rigor of psychedelic clinical trials. Psychopharmacology. PMID 35359159 DOI: 10.1007/s00213-022-06123-7  0.063
2022 Chow HS, Hack LM, Kawai M, Heifets BD. Anesthetic-Induced Intraoperative Dream Associated With Remission of a Psychiatric Disorder: A Case Report. A&a Practice. 16: e01613. PMID 35952341 DOI: 10.1213/XAA.0000000000001613  0.063
2022 McInnes LA, Qian JJ, Gargeya RS, DeBattista C, Heifets BD. A retrospective analysis of ketamine intravenous therapy for depression in real-world care settings. Journal of Affective Disorders. PMID 35027209 DOI: 10.1016/j.jad.2021.12.097  0.058
2022 Reese M, Heifets BD, Berger M. Intraoperative Anesthetic Probes of Brain Health: Ketamine as a Canary in the Coal Mine? Anesthesia and Analgesia. 135: 679-682. PMID 36108180 DOI: 10.1213/ANE.0000000000005965  0.058
2024 Verdonk F, Cambriel A, Hedou J, Ganio E, Bellan G, Gaudilliere D, Einhaus J, Sabayev M, Stelzer IA, Feyaerts D, Bonham AT, Ando K, Choisy B, Drover D, Heifets B, et al. An immune signature of postoperative cognitive decline in elderly patients. Biorxiv : the Preprint Server For Biology. PMID 38496400 DOI: 10.1101/2024.03.02.582845  0.057
2023 Lii TR, Smith AE, Flohr JR, Okada RL, Nyongesa CA, Cianfichi LJ, Hack LM, Schatzberg AF, Heifets BD. Trial of Ketamine Masked by Surgical Anesthesia in Depressed Patients. Medrxiv : the Preprint Server For Health Sciences. PMID 37205558 DOI: 10.1101/2023.04.28.23289210  0.056
2021 Heifets BD, Bentzley BS, Williams N, Schatzberg AF. Unraveling the opioid actions of S-ketamine and R-ketamine: comment on Bonaventura et al. Molecular Psychiatry. PMID 34006965 DOI: 10.1038/s41380-021-01167-1  0.055
2022 Bombardieri AM, Heifets BD, Treggiari M, Albers GW, Steinberg GK, Heit JJ. Cervical sympathectomy to treat cerebral vasospasm: a scoping review. Regional Anesthesia and Pain Medicine. PMID 36424089 DOI: 10.1136/rapm-2022-103999  0.043
2018 Heifets BD, Crawford E, Jackson E, Brodt J, Jaffe RA, Burbridge MA. Case Report of an Awake Craniotomy in a Patient With Eisenmenger Syndrome. A&a Practice. 10: 219-222. PMID 29708913 DOI: 10.1213/XAA.0000000000000664  0.021
2017 Heifets BD, Crawford E, Jackson E, Brodt J, Jaffe RA, Burbridge MA. Case Report of an Awake Craniotomy in a Patient With Eisenmenger Syndrome. A & a Case Reports. PMID 29135526 DOI: 10.1213/XAA.0000000000000664  0.021
2023 Ruiz Colón GD, Ohkuma R, Pendharkar AV, Heifets BD, Li G, Lu A, Gephart MH, Ratliff JK. A Protocol for Reducing Intensive Care Utilization After Craniotomy: A 3-Year Assessment. Neurosurgery. PMID 36639854 DOI: 10.1227/neu.0000000000002337  0.016
2020 Heifets BD. Piercing the Ketamine Cloud. Anesthesiology. PMID 32946552 DOI: 10.1097/ALN.0000000000003562  0.01
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