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Katie I. Amssoms, Dr. - Publications

Affiliations: 
2002 Universitaire Instelling Antwerpen (Belgium) 
Area:
Pharmaceutical Chemistry, Pharmacology, Organic Chemistry
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4/23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, et al. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. Journal of Medicinal Chemistry. 52: 4099-102. PMID 19507864 DOI: 10.1021/jm9005548  0.314
2005 Verschueren WG, Dierynck I, Amssoms KI, Hu L, Boonants PM, Pille GM, Daeyaert FF, Hertogs K, Surleraux DL, Wigerinck PB. Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase. Journal of Medicinal Chemistry. 48: 1930-40. PMID 15771437 DOI: 10.1021/jm049559q  0.368
2002 Amssoms K, Oza SL, Augustyns K, Yamani A, Lambeir AM, Bal G, Van der Veken P, Fairlamb AH, Haemers A. Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 2: substitution of the glycine part. Bioorganic & Medicinal Chemistry Letters. 12: 2703-5. PMID 12217358 DOI: 10.1016/S0960-894X(02)00538-3  0.464
2002 Amssoms K, Oza SL, Ravaschino E, Yamani A, Lambeir A, Rajan P, Bal G, Rodriguez J, Fairlamb AH, Augustyns K, Haemers A. Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 1: Substitution of the glycine carboxylic acid group. Bioorganic & Medicinal Chemistry Letters. 12: 2553-6. PMID 12182858 DOI: 10.1016/S0960-894X(02)00489-4  0.463
Low-probability matches (unlikely to be authored by this person)
2012 McGowan D, Vendeville S, Lin TI, Tahri A, Hu L, Cummings MD, Amssoms K, Berke JM, Canard M, Cleiren E, Dehertogh P, Last S, Fransen E, Van Der Helm E, Van den Steen I, et al. Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series. Bioorganic & Medicinal Chemistry Letters. 22: 4431-6. PMID 22542193 DOI: 10.1016/j.bmcl.2012.03.097  0.28
2018 Embrechts W, Herschke F, Pauwels F, Stoops B, Last S, Pieters S, Pande V, Pille G, Amssoms K, Smyej I, Dhuyvetter D, Scholliers A, Mostmans W, Van Dijck K, Van Schoubroeck B, et al. 2,4-Diaminoquinazolines as Dual Toll Like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus. Journal of Medicinal Chemistry. PMID 29965759 DOI: 10.1021/Acs.Jmedchem.8B00643  0.239
2013 Kesteleyn B, Amssoms K, Schepens W, Hache G, Verschueren W, Van De Vreken W, Rombauts K, Meurs G, Sterkens P, Stoops B, Baert L, Austin N, Wegner J, Masungi C, Dierynck I, et al. Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application. Bioorganic & Medicinal Chemistry Letters. 23: 310-7. PMID 23177258 DOI: 10.1016/j.bmcl.2012.10.095  0.233
2012 Vendeville S, Lin TI, Hu L, Tahri A, McGowan D, Cummings MD, Amssoms K, Canard M, Last S, Van den Steen I, Devogelaere B, Rouan MC, Vijgen L, Berke JM, Dehertogh P, et al. Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055. Bioorganic & Medicinal Chemistry Letters. 22: 4437-43. PMID 22633687 DOI: 10.1016/j.bmcl.2012.04.113  0.218
2014 Cummings MD, Lin TI, Hu L, Tahri A, McGowan D, Amssoms K, Last S, Devogelaere B, Rouan MC, Vijgen L, Berke JM, Dehertogh P, Fransen E, Cleiren E, van der Helm L, et al. Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase. Journal of Medicinal Chemistry. 57: 1880-92. PMID 24144360 DOI: 10.1021/jm401396p  0.213
2009 McGowan D, Nyanguile O, Cummings MD, Vendeville S, Vandyck K, Van den Broeck W, Boutton CW, De Bondt H, Quirynen L, Amssoms K, Bonfanti JF, Last S, Rombauts K, Tahri A, Hu L, et al. 1,5-Benzodiazepine inhibitors of HCV NS5B polymerase. Bioorganic & Medicinal Chemistry Letters. 19: 2492-6. PMID 19342234 DOI: 10.1016/j.bmcl.2009.03.035  0.17
2012 Cummings MD, Lin TI, Hu L, Tahri A, McGowan D, Amssoms K, Last S, Devogelaere B, Rouan MC, Vijgen L, Berke JM, Dehertogh P, Fransen E, Cleiren E, van der Helm L, et al. Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties. Angewandte Chemie (International Ed. in English). 51: 4637-40. PMID 22473861 DOI: 10.1002/anie.201200110  0.155
2016 Murphy DJ, Amssoms K, Pille G, Clarke A, O'Hara M, van Roey J, Malcolm RK. Sustained release of the candidate antiretroviral peptides T-1249 and JNJ54310516-AFP from a rod insert vaginal ring. Drug Delivery and Translational Research. 6: 234-42. PMID 26787615 DOI: 10.1007/s13346-015-0273-8  0.153
2015 Meeus J, Scurr DJ, Amssoms K, Wuyts K, Annaert P, Davies MC, Roberts CJ, Van den Mooter G. In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor. Journal of Controlled Release : Official Journal of the Controlled Release Society. 199: 1-9. PMID 25485732 DOI: 10.1016/j.jconrel.2014.11.020  0.143
2012 Devogelaere B, Berke JM, Vijgen L, Dehertogh P, Fransen E, Cleiren E, van der Helm L, Nyanguile O, Tahri A, Amssoms K, Lenz O, Cummings MD, Clayton RF, Vendeville S, Raboisson P, et al. TMC647055, a potent nonnucleoside hepatitis C virus NS5B polymerase inhibitor with cross-genotypic coverage. Antimicrobial Agents and Chemotherapy. 56: 4676-84. PMID 22710121 DOI: 10.1128/AAC.00245-12  0.127
2012 Meeus J, Chen X, Scurr DJ, Ciarnelli V, Amssoms K, Roberts CJ, Davies MC, van Den Mooter G. Nanoscale surface characterization and miscibility study of a spray-dried injectable polymeric matrix consisting of poly(lactic-co-glycolic acid) and polyvinylpyrrolidone. Journal of Pharmaceutical Sciences. 101: 3473-85. PMID 22447580 DOI: 10.1002/jps.23131  0.12
2018 Beugeling M, Grasmeijer N, Born PA, van der Meulen M, van der Kooij RS, Schwengle K, Baert L, Amssoms K, Frijlink HW, Hinrichs WLJ. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts. International Journal of Pharmaceutics. 551: 195-202. PMID 30223077 DOI: 10.1016/j.ijpharm.2018.09.025  0.108
2013 Meeus J, Scurr DJ, Amssoms K, Davies MC, Roberts CJ, Van den Mooter G. Surface characteristics of spray-dried microspheres consisting of PLGA and PVP: relating the influence of heat and humidity to the thermal characteristics of these polymers. Molecular Pharmaceutics. 10: 3213-24. PMID 23844639 DOI: 10.1021/mp400263d  0.099
2018 Amssoms K, Born PA, Beugeling M, De Clerck B, Van Gulck E, Hinrichs WLJ, Frijlink HW, Grasmeijer N, Kraus G, Sutmuller R, Simmen K, Baert L. Ovalbumin-containing core-shell implants suitable to obtain a delayed IgG1 antibody response in support of a biphasic pulsatile release profile in mice. Plos One. 13: e0202961. PMID 30161264 DOI: 10.1371/journal.pone.0202961  0.074
2014 Meeus J, Scurr DJ, Chen X, Amssoms K, Davies MC, Roberts CJ, Van den Mooter G. Combination of (M)DSC and surface analysis to study the phase behaviour and drug distribution of ternary solid dispersions. Pharmaceutical Research. 32: 1407-16. PMID 25319105 DOI: 10.1007/s11095-014-1543-8  0.074
2012 Nischang M, Sutmuller R, Gers-Huber G, Audigé A, Li D, Rochat MA, Baenziger S, Hofer U, Schlaepfer E, Regenass S, Amssoms K, Stoops B, Van Cauwenberge A, Boden D, Kraus G, et al. Humanized mice recapitulate key features of HIV-1 infection: a novel concept using long-acting anti-retroviral drugs for treating HIV-1. Plos One. 7: e38853. PMID 22719966 DOI: 10.1371/journal.pone.0038853  0.069
2014 Meeus J, Scurr DJ, Appeltans B, Amssoms K, Annaert P, Davies MC, Roberts CJ, Van den Mooter G. Influence of formulation composition and process on the characteristics and in vitro release from PLGA-based sustained release injectables. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 90: 22-9. PMID 25448071 DOI: 10.1016/j.ejpb.2014.11.009  0.066
2015 Meeus J, Lenaerts M, Scurr DJ, Amssoms K, Davies MC, Roberts CJ, Van Den Mooter G. The influence of spray-drying parameters on phase behavior, drug distribution, and in vitro release of injectable microspheres for sustained release. Journal of Pharmaceutical Sciences. 104: 1451-60. PMID 25648704 DOI: 10.1002/jps.24361  0.065
2019 Beugeling M, Amssoms K, Cox F, De Clerck B, Van Gulck E, Verwoerd JA, Kraus G, Roymans D, Baert L, Frijlink HW, Hinrichs WLJ. Development of a Stable Respiratory Syncytial Virus Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a Delayed Release in Mice: A Proof of Concept Study. Pharmaceutics. 11. PMID 31623333 DOI: 10.3390/pharmaceutics11100510  0.037
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