| Year |
Citation |
Score |
| 2023 |
Rodriguez JB, Szajnman SH. An updated review of chemical compounds with anti-Toxoplasma gondii activity. European Journal of Medicinal Chemistry. 262: 115885. PMID 37871407 DOI: 10.1016/j.ejmech.2023.115885 |
0.729 |
|
| 2023 |
Sonego JM, De Diego SI, Szajnman SH, Gallo-Rodriguez C, Rodriguez JB. Organoselenium compounds. Chemistry and applications in organic synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). e202300030. PMID 37378970 DOI: 10.1002/chem.202300030 |
0.789 |
|
| 2020 |
Castillo AF, Orlando UD, Maloberti PM, Prada JG, Dattilo MA, Solano AR, Bigi MM, Ríos Medrano MA, Torres MT, Indo S, Caroca G, Contreras HR, Marelli BE, Salinas FJ, Salvetti NR, et al. New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis. Cellular and Molecular Life Sciences : Cmls. PMID 33068124 DOI: 10.1007/s00018-020-03679-5 |
0.681 |
|
| 2020 |
Szajnman SH, Rodriguez JB, Chao MN, Cattaneo M, Sanchez Gonzalez J, Bonesi SM. Synthetic and Mechanistic Studies on 2,3-Dihydrobenzo[b][1,4]-oxaselenines Formation from Selenocyanates Synthesis. 52: 1643-1658. DOI: 10.1055/s-0039-1690800 |
0.779 |
|
| 2019 |
Galaka T, Falcone BN, Li C, Szajnman SH, Moreno SNJ, Docampo R, Rodriguez JB. Synthesis and biological evaluation of 1-alkylaminomethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii. Bioorganic & Medicinal Chemistry. PMID 31296439 DOI: 10.1016/J.Bmc.2019.07.004 |
0.816 |
|
| 2019 |
Chao MN, Lorenzo-Ocampo MV, Szajnman SH, Docampo R, Rodriguez JB. Further insights of selenium-containing analogues of WC-9 against Trypanosoma cruzi. Bioorganic & Medicinal Chemistry. PMID 30808607 DOI: 10.1016/J.Bmc.2019.02.039 |
0.828 |
|
| 2018 |
Falcone BN, Grayson MN, Rodriguez JB. Mechanistic Insights into a Chiral Phosphoric Acid-Catalyzed Asymmetric Pinacol Rearrangement. The Journal of Organic Chemistry. PMID 30433780 DOI: 10.1021/acs.joc.8b02812 |
0.766 |
|
| 2017 |
Chao MN, Storey M, Li C, Rodríguez MG, Di Salvo F, Szajnman SH, Moreno SNJ, Docampo R, Rodriguez JB. Selenium-containing analogues of WC-9 are extremely potent inhibitors of Trypanosoma cruzi proliferation. Bioorganic & Medicinal Chemistry. PMID 29107437 DOI: 10.1016/J.Bmc.2017.10.016 |
0.848 |
|
| 2017 |
Li ZH, Li C, Szajnman SH, Rodriguez JB, Moreno SNJ. Synergistic Activity between Statins and Bisphosphonates against Acute Experimental Toxoplasmosis. Antimicrobial Agents and Chemotherapy. PMID 28559264 DOI: 10.1128/AAC.02628-16 |
0.768 |
|
| 2017 |
Galaka T, Ferrer Casal M, Storey M, Li C, Chao MN, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Antiparasitic Activity of Sulfur- and Fluorine-Containing Bisphosphonates against Trypanosomatids and Apicomplexan Parasites. Molecules (Basel, Switzerland). 22. PMID 28054995 DOI: 10.3390/Molecules22010082 |
0.809 |
|
| 2016 |
Szajnman SH, Galaka T, Li ZH, Li C, Howell NM, Chao MN, Striepen B, Muralidharan V, Moreno SN, Rodriguez JB. 1. In Vitro and In Vivo Activity of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites. Antimicrobial Agents and Chemotherapy. PMID 27895021 DOI: 10.1128/AAC.01590-16 |
0.8 |
|
| 2016 |
Chao MN, Li C, Storey M, Falcone BN, Szajnman SH, Bonesi SM, Docampo R, Moreno SN, Rodriguez JB. Activity of Fluorine-Containing Analogues of WC-9 and Structurally Related Analogues against Two Intracellular Parasites: Trypanosoma cruzi and Toxoplasma gondii. Chemmedchem. PMID 27886451 DOI: 10.1002/Cmdc.201600505 |
0.82 |
|
| 2016 |
Rodriguez JB, Falcone BN, Szajnman SH. Detection and treatment of Trypanosoma cruzi: a patent review (2011-2015). Expert Opinion On Therapeutic Patents. PMID 27376456 DOI: 10.1080/13543776.2016.1209487 |
0.788 |
|
| 2016 |
Rodriguez JB. WC-9 a Lead Drug with Great Prospects for American Trypanosomiasis and Toxoplasmosis. Mini Reviews in Medicinal Chemistry. PMID 27290911 DOI: 10.2174/1389557516666160611015034 |
0.431 |
|
| 2016 |
Rodriguez JB, Falcone BN, Szajnman SH. Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase. Expert Opinion On Drug Discovery. 11: 307-20. PMID 26781029 DOI: 10.1517/17460441.2016.1143814 |
0.794 |
|
| 2016 |
Rodriguez JB, Falcone BN, Szajnman SH. Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase Expert Opinion On Drug Discovery. 11: 307-320. DOI: 10.1517/17460441.2016.1143814 |
0.791 |
|
| 2015 |
Chao MN, Matiuzzi CE, Storey M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors of Trypanosoma cruzi and Toxoplasma gondii. Chemmedchem. 10: 1094-108. PMID 25914175 DOI: 10.1002/Cmdc.201500100 |
0.849 |
|
| 2014 |
Lai DH, Poropat E, Pravia C, Landoni M, Couto AS, Rojo FG, Fuchs AG, Dubin M, Elingold I, Rodríguez JB, Ferella M, Esteva MI, Bontempi EJ, Lukes J. Solanesyl diphosphate synthase, an enzyme of the ubiquinone synthetic pathway, is required throughout the life cycle of Trypanosoma brucei. Eukaryotic Cell. 13: 320-8. PMID 24376001 DOI: 10.1128/EC.00271-13 |
0.332 |
|
| 2014 |
Ferrer-Casal M, Li C, Galizzi M, Stortz CA, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase. Bioorganic & Medicinal Chemistry. 22: 398-405. PMID 24300918 DOI: 10.1016/J.Bmc.2013.11.010 |
0.835 |
|
| 2014 |
Ferrer-Casal M, Barboza AP, Szajnman SH, Rodriguez JB. ChemInform Abstract: 1,3-Dipolar Cycloadditions of the Versatile Intermediate Tetraethyl Vinylidenebisphosphonate. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201406159 |
0.76 |
|
| 2013 |
Elicio PD, Chao MN, Galizzi M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents. European Journal of Medicinal Chemistry. 69: 480-9. PMID 24090919 DOI: 10.1016/J.Ejmech.2013.09.009 |
0.847 |
|
| 2013 |
Recher M, Barboza AP, Li ZH, Galizzi M, Ferrer-Casal M, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents. European Journal of Medicinal Chemistry. 60: 431-40. PMID 23318904 DOI: 10.1016/J.Ejmech.2012.12.015 |
0.818 |
|
| 2013 |
Szajnman S, Rodriguez J, Ferrer-Casal M, Barboza A. 1,3-Dipolar Cycloadditions of the Versatile Intermediate Tetraethyl Vinylidenebisphosphonate Synthesis. 45: 2397-2404. DOI: 10.1055/S-0033-1338498 |
0.76 |
|
| 2012 |
Aripirala S, Szajnman SH, Jakoncic J, Rodriguez JB, Docampo R, Gabelli SB, Amzel LM. Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. Journal of Medicinal Chemistry. 55: 6445-54. PMID 22715997 DOI: 10.1021/Jm300425Y |
0.784 |
|
| 2012 |
Rodrígues-Poveda CA, González-Pacanowska D, Szajnman SH, Rodríguez JB. 2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase. Antimicrobial Agents and Chemotherapy. 56: 4483-6. PMID 22585217 DOI: 10.1128/AAC.00796-12 |
0.775 |
|
| 2012 |
Rodriguez JB, Szajnman SH. New antibacterials for the treatment of toxoplasmosis; a patent review. Expert Opinion On Therapeutic Patents. 22: 311-33. PMID 22404108 DOI: 10.1517/13543776.2012.668886 |
0.706 |
|
| 2012 |
Szajnman SH, Rosso VS, Malayil L, Smith A, Moreno SN, Docampo R, Rodriguez JB. 1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase. Organic & Biomolecular Chemistry. 10: 1424-33. PMID 22215028 DOI: 10.1039/C1Ob06602A |
0.818 |
|
| 2011 |
Molinas MF, De Candia A, Szajnman SH, Rodríguez JB, Martí M, Pereira M, Teixeira M, Todorovic S, Murgida DH. Electron transfer dynamics of Rhodothermus marinus caa3 cytochrome c domains on biomimetic films. Physical Chemistry Chemical Physics : Pccp. 13: 18088-98. PMID 21922088 DOI: 10.1039/C1Cp21925A |
0.636 |
|
| 2011 |
Rosso VS, Szajnman SH, Malayil L, Galizzi M, Moreno SN, Docampo R, Rodriguez JB. Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorganic & Medicinal Chemistry. 19: 2211-7. PMID 21419634 DOI: 10.1016/J.Bmc.2011.02.037 |
0.812 |
|
| 2010 |
Elhalem E, Pujol CA, Damonte EB, Rodriguez JB. Synthesis and biological evaluation of N-thia-carba-thymidine as an antiherpetic agent Tetrahedron. 66: 3332-3340. DOI: 10.1016/J.TET.2010.02.092 |
0.773 |
|
| 2010 |
Szajnman SH, Bailey BN, Docampo R, Rodriguez JB. ChemInform Abstract: Bisphosphonates Derived from Fatty Acids Are Potent Growth Inhibitors of Trypanosoma cruzi. Cheminform. 32: no-no. DOI: 10.1002/CHIN.200127218 |
0.72 |
|
| 2010 |
Szajnman SH, Yan W, Bailey BN, Docampo R, Elhalem E, Rodriguez JB. ChemInform Abstract: Design and Synthesis of Aryloxyethyl Thiocyanate Derivatives as Potent Inhibitors of Trypanosoma cruzi Proliferation. Cheminform. 31: no-no. DOI: 10.1002/chin.200029071 |
0.812 |
|
| 2010 |
Comin MJ, Pujol CA, Damonte EB, Rodriguez JB. ChemInform Abstract: Synthesis of C-5′-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200010208 |
0.63 |
|
| 2010 |
SCHVARTZAPEL AJ, ZHONG L, DOCAMPO R, RODRIGUEZ JB, GROS EG. ChemInform Abstract: Design, Synthesis, and Biological Evaluation of New Growth Inhibitors of Trypanosoma cruzi (Epimastigotes). Cheminform. 28: no-no. DOI: 10.1002/chin.199745219 |
0.804 |
|
| 2008 |
Szajnman SH, García Liñares GE, Li ZH, Jiang C, Galizzi M, Bontempi EJ, Ferella M, Moreno SN, Docampo R, Rodriguez JB. Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorganic & Medicinal Chemistry. 16: 3283-90. PMID 18096393 DOI: 10.1016/j.bmc.2007.12.010 |
0.817 |
|
| 2007 |
Liñares GG, Gismondi S, Codesido NO, Moreno SN, Docampo R, Rodriguez JB. Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation. Bioorganic & Medicinal Chemistry Letters. 17: 5068-71. PMID 17643987 DOI: 10.1016/J.Bmcl.2007.07.012 |
0.84 |
|
| 2006 |
Liñares GE, Ravaschino EL, Rodriguez JB. Progresses in the field of drug design to combat tropical protozoan parasitic diseases. Current Medicinal Chemistry. 13: 335-60. PMID 16475941 |
0.809 |
|
| 2006 |
Ravaschino EL, Docampo R, Rodriguez JB. Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis. Journal of Medicinal Chemistry. 49: 426-35. PMID 16392828 DOI: 10.1021/Jm050922I |
0.843 |
|
| 2006 |
Elhalem E, Comin MJ, Rodriguez JB. Synthesis of Conformationally Locked Carbocyclic Nucleosides Built on a Thiabicyclo[3.1.0]hexane System as a Pseudosugar Surrogate European Journal of Organic Chemistry. 2006: 4473-4482. DOI: 10.1002/EJOC.200600488 |
0.788 |
|
| 2005 |
Szajnman SH, Ravaschino EL, Docampo R, Rodriguez JB. Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase. Bioorganic & Medicinal Chemistry Letters. 15: 4685-90. PMID 16143525 DOI: 10.1016/J.Bmcl.2005.07.060 |
0.829 |
|
| 2005 |
Elhalem E, Comin MJ, Leitofuter J, García-Liñares G, Rodriguez JB. Synthetic studies toward the preparation of (4R,5R)-(−)-3-[(benzyloxy)methyl]-4,5-O-isopropylidene-cyclopenten-2-one: an important synthetic intermediate for carbanucleosides Tetrahedron: Asymmetry. 16: 425-431. DOI: 10.1016/J.TETASY.2004.11.069 |
0.753 |
|
| 2005 |
Szajnman SH, García Liñares G, Moro P, Rodriguez JB. New Insights into the Chemistry ofgem-Bis(phosphonates): Unexpected Rearrangement of Michael-Type Acceptors European Journal of Organic Chemistry. 2005: 3687-3696. DOI: 10.1002/EJOC.200500097 |
0.667 |
|
| 2004 |
Gao ZG, Jeong LS, Moon HR, Kim HO, Choi WJ, Shin DH, Elhalem E, Comin MJ, Melman N, Mamedova L, Gross AS, Rodriguez JB, Jacobson KA. Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety. Biochemical Pharmacology. 67: 893-901. PMID 15104242 DOI: 10.1016/J.Bcp.2003.10.006 |
0.769 |
|
| 2004 |
Comin MJ, Elhalem E, Rodriguez JB. Cerium ammonium nitrate: a new catalyst for regioselective protection of glycols Tetrahedron. 60: 11851-11860. DOI: 10.1016/J.TET.2004.09.097 |
0.755 |
|
| 2003 |
Szajnman SH, Montalvetti A, Wang Y, Docampo R, Rodriguez JB. Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase Bioorganic and Medicinal Chemistry Letters. 13: 3231-3235. PMID 12951099 DOI: 10.1016/S0960-894X(03)00663-2 |
0.783 |
|
| 2003 |
Urbina JA, Concepcion JL, Montalvetti A, Rodriguez JB, Docampo R. Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease. Antimicrobial Agents and Chemotherapy. 47: 2047-50. PMID 12760897 DOI: 10.1128/Aac.47.6.2047-2050.2003 |
0.607 |
|
| 2003 |
Rodríguez JB, Comin MJ. New progresses in the enantioselective synthesis and biological properties of carbocyclic nucleosides. Mini Reviews in Medicinal Chemistry. 3: 95-114. PMID 12570843 DOI: 10.2174/1389557033405331 |
0.786 |
|
| 2003 |
Comin MJ, Rodriguez JB, Russ P, Marquez VE. Synthesis of conformationally locked carbocyclic nucleosides built on an oxabicyclo[3.1.0]hexane system Tetrahedron. 59: 295-301. DOI: 10.1016/S0040-4020(02)01528-4 |
0.67 |
|
| 2003 |
Rodriguez JB, Comin MJ. New Progresses in the Enantioselective Synthesis and Biological Properties of Carbocyclic Nucleosides Cheminform. 34. DOI: 10.1002/CHIN.200336234 |
0.672 |
|
| 2002 |
Elhalem E, Bailey BN, Docampo R, Ujváry I, Szajnman SH, Rodriguez JB. Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi. Journal of Medicinal Chemistry. 45: 3984-99. PMID 12190320 DOI: 10.1021/Jm0201518 |
0.847 |
|
| 2002 |
Amssoms K, Oza SL, Ravaschino E, Yamani A, Lambeir A, Rajan P, Bal G, Rodriguez J, Fairlamb AH, Augustyns K, Haemers A. Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 1: Substitution of the glycine carboxylic acid group. Bioorganic & Medicinal Chemistry Letters. 12: 2553-6. PMID 12182858 DOI: 10.1016/S0960-894X(02)00489-4 |
0.803 |
|
| 2002 |
Comin MJ, Leitofuter J, Rodrı́guez JB. Enantioselective synthesis of (+)-neplanocin F Tetrahedron. 58: 3129-3136. DOI: 10.1016/S0040-4020(02)00287-9 |
0.621 |
|
| 2000 |
Comin MJ, Rodriguez JB. ChemInform Abstract: First Synthesis of (-)-Neplanocin C. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200042214 |
0.638 |
|
| 1996 |
Rodriguez JB, Zhong L, Docampo R, Gros EG. Biological evaluation of two potent inhibitors of Trypanosoma cruzi epimastigotes against the intracellular form of the parasite Bioorganic and Medicinal Chemistry Letters. 6: 2783-2786. DOI: 10.1016/S0960-894X(96)00517-3 |
0.558 |
|
| 1995 |
Schvartzapel AJ, Fichera L, Esteva M, Rodriguez JB, Gros EG. Design, synthesis, and anti‐ Trypanosoma cruzi evaluation of a new class of cell‐growth inhibitors structurally related to Fenoxycarb Helvetica Chimica Acta. 78: 1207-1214. DOI: 10.1002/hlca.19950780513 |
0.828 |
|
| 1990 |
Stoka AM, Rodriguez JB, Rivas C, Grosb EG, Seguraa EL. Biological Activity of Synthetic Juvenile Hormone Analogues (JHA) for Trypanosoma cruzi Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences. 45: 96-98. DOI: 10.1515/znb-1990-0119 |
0.35 |
|
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