Year |
Citation |
Score |
2015 |
Liu L, Collier AC, Link JM, Domino KB, Mankoff DA, Eary JF, Spiekerman CF, Hsiao P, Deo AK, Unadkat JD. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1795-804. PMID 26354948 DOI: 10.1124/Dmd.114.058685 |
0.695 |
|
2014 |
Deo AK, Borson S, Link JM, Domino K, Eary JF, Ke B, Richards TL, Mankoff DA, Minoshima S, O'Sullivan F, Eyal S, Hsiao P, Maravilla K, Unadkat JD. Activity of P-Glycoprotein, a β-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1106-11. PMID 24842892 DOI: 10.2967/Jnumed.113.130161 |
0.508 |
|
2014 |
Hsiao P, Unadkat JD. Predicting the outer boundaries of P-glycoprotein (P-gp)-based drug interactions at the human blood-brain barrier based on rat studies. Molecular Pharmaceutics. 11: 436-44. PMID 24364805 DOI: 10.1021/Mp400396K |
0.721 |
|
2014 |
Lai Y, Hsiao P. Beyond the ITC White Paper: emerging sciences in drug transporters and opportunities for drug development. Current Pharmaceutical Design. 20: 1577-94. PMID 23789952 DOI: 10.2174/13816128113199990467 |
0.317 |
|
2012 |
Hsiao P, Unadkat JD. P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans. Molecular Pharmaceutics. 9: 629-33. PMID 22316009 DOI: 10.1021/Mp200563A |
0.691 |
|
2012 |
Deo A, Borson S, Link J, Eary J, Richards T, Mankoff D, Hsiao P, Minoshima S, Maravilla K, Unadkat J. Activity of P-glycoprotein, an ABC efflux transporter at the blood-brain barrier, is compromised in Alzheimer's disease Alzheimers & Dementia. 8: 698. DOI: 10.1016/J.Jalz.2012.05.1880 |
0.701 |
|
2010 |
Chung FS, Eyal S, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hsiao P, Unadkat JD. Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primate. British Journal of Pharmacology. 159: 394-404. PMID 20002098 DOI: 10.1111/J.1476-5381.2009.00538.X |
0.582 |
|
2009 |
Eyal S, Hsiao P, Unadkat JD. Drug interactions at the blood-brain barrier: fact or fantasy? Pharmacology & Therapeutics. 123: 80-104. PMID 19393264 DOI: 10.1016/J.Pharmthera.2009.03.017 |
0.658 |
|
2008 |
Hsiao P, Bui T, Ho RJ, Unadkat JD. In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 481-4. PMID 18057117 DOI: 10.1124/Dmd.107.018176 |
0.689 |
|
2006 |
Hsiao P, Sasongko L, Link JM, Mankoff DA, Muzi M, Collier AC, Unadkat JD. Verapamil P-glycoprotein transport across the rat blood-brain barrier: cyclosporine, a concentration inhibition analysis, and comparison with human data. The Journal of Pharmacology and Experimental Therapeutics. 317: 704-10. PMID 16415090 DOI: 10.1124/Jpet.105.097931 |
0.695 |
|
2006 |
Endres CJ, Hsiao P, Chung FS, Unadkat JD. The role of transporters in drug interactions. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 501-17. PMID 16364611 DOI: 10.1016/J.Ejps.2005.11.002 |
0.644 |
|
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