| Year |
Citation |
Score |
| 2018 |
El-Mesallamy HO, El Magdoub HM, Chapman JM, Hamdy NM, Schaalan MF, Hammad LN, Berger SH. Biomolecular study of human thymidylate synthase conformer-selective inhibitors: New chemotherapeutic approach. Plos One. 13: e0193810. PMID 29538414 DOI: 10.1371/Journal.Pone.0193810 |
0.633 |
|
| 2013 |
Yousef AM, Shomaf M, Berger S, Ababneh N, Bobali Y, Ali D, Al-Hasan S, Diab O, Ismail S. Allele and genotype frequencies of the polymorphic methylenetetrahydrofolate reductase and colorectal cancer among Jordanian population. Asian Pacific Journal of Cancer Prevention : Apjcp. 14: 4559-65. PMID 24083702 DOI: 10.7314/Apjcp.2013.14.8.4559 |
0.609 |
|
| 2011 |
Luo B, Johnson SR, Lebioda L, Berger SH. Evolution of metamorphism in thymidylate synthases within the primate lineages. Journal of Molecular Evolution. 72: 306-14. PMID 21318388 DOI: 10.1007/S00239-011-9433-8 |
0.735 |
|
| 2011 |
Luo B, Repalli J, Yousef AM, Johnson SR, Lebioda L, Berger SH. Human thymidylate synthase with loop 181-197 stabilized in an inactive conformation: ligand interactions, phosphorylation, and inhibition profiles. Protein Science : a Publication of the Protein Society. 20: 87-94. PMID 21064161 DOI: 10.1002/Pro.539 |
0.639 |
|
| 2011 |
Repalli J, Chapman J, McInnes C, Berger SH. Abstract 1348: The discovery of novel inhibitors that downregulate human thymidylate synthase Cancer Research. 71: 1348-1348. DOI: 10.1158/1538-7445.Am2011-1348 |
0.728 |
|
| 2010 |
Huang X, Gibson LM, Bell BJ, Lovelace LL, Peña MM, Berger FG, Berger SH, Lebioda L. Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry. 49: 2475-82. PMID 20151707 DOI: 10.1021/Bi901457E |
0.576 |
|
| 2010 |
Repalli J, Robinson MR, Gumina G, Berger SH. Abstract 5508: Screening Of Novel Thymidylate Synthase Inhibitors Cancer Research. 70: 5508-5508. DOI: 10.1158/1538-7445.Am10-5508 |
0.715 |
|
| 2010 |
Luo B, Berger SH. Abstract 2670: CONFORMATIONAL PLASTICITY OF HUMAN THYMIDYLATE SYNTHASE Cancer Research. 70: 2670-2670. DOI: 10.1158/1538-7445.Am10-2670 |
0.614 |
|
| 2009 |
Lovelace LL, Johnson SR, Gibson LM, Bell BJ, Berger SH, Lebioda L. Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation. Protein Science : a Publication of the Protein Society. 18: 1628-36. PMID 19569192 DOI: 10.1002/Pro.171 |
0.711 |
|
| 2006 |
You S, Ohmori M, Peña MM, Nassri B, Quiton J, Al-Assad ZA, Liu L, Wood PA, Berger SH, Liu Z, Wyatt MD, Price RL, Berger FG, Hrushesky WJ. Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice. International Journal of Experimental Pathology. 87: 227-36. PMID 16709231 DOI: 10.1111/J.1365-2613.2006.00477.X |
0.597 |
|
| 2005 |
Li L, Connor EE, Berger SH, Wyatt MD. Determination of apoptosis, uracil incorporation, DNA strand breaks, and sister chromatid exchanges under conditions of thymidylate deprivation in a model of BER deficiency. Biochemical Pharmacology. 70: 1458-68. PMID 16191427 DOI: 10.1016/J.Bcp.2005.08.016 |
0.336 |
|
| 2004 |
Berger SH, Berger FG, Lebioda L. Effects of ligand binding and conformational switching on intracellular stability of human thymidylate synthase. Biochimica Et Biophysica Acta. 1696: 15-22. PMID 14726200 DOI: 10.1016/J.Bbapap.2003.09.005 |
0.59 |
|
| 2001 |
Yousef AM, Davis RA, Sticca RP, Berger SH. Structural analysis of cDNA encoding thymidylate synthase in hepatic metastases of human colorectal tumors. International Journal of Colorectal Disease. 16: 318-25. PMID 11686531 DOI: 10.1007/S003840100319 |
0.631 |
|
| 2001 |
Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L. Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug. Biochemistry. 40: 1897-902. PMID 11329255 DOI: 10.1021/Bi002413I |
0.379 |
|
| 2001 |
Phan J, Steadman DJ, Koli S, Ding WC, Minor W, Dunlap RB, Berger SH, Lebioda L. Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors. The Journal of Biological Chemistry. 276: 14170-7. PMID 11278511 DOI: 10.1074/Jbc.M009493200 |
0.577 |
|
| 2000 |
Phan J, Mahdavian E, Nivens MC, Minor W, Berger S, Spencer HT, Dunlap RB, Lebioda L. Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry. 39: 6969-78. PMID 10841779 DOI: 10.1021/Bi000367G |
0.377 |
|
| 1999 |
Hoganson DK, Williams AW, Berger SH. Isolation and characterization of a thymidylate synthase-deficient human colon tumor cell line. Biochemical Pharmacology. 58: 1529-37. PMID 10535743 DOI: 10.1016/S0006-2952(99)00237-3 |
0.32 |
|
| 1999 |
Zapf JW, Zhao PS, Steadman DJ, Berger SH. Genetic complementation and resistance to 5-fluoro-2'-deoxyuridine in thymidine auxotrophs expressing a highly defective mutant of human thymidylate synthase. Biochemical Pharmacology. 58: 973-81. PMID 10509749 DOI: 10.1016/S0006-2952(99)00187-2 |
0.41 |
|
| 1999 |
Steadman DJ, Spencer HT, Dunlap RB, Berger SH. Substitution at residue 214 of human thymidylate synthase alters nucleotide binding and isomerization of ligand-protein complexes. Biochemistry. 38: 5582-7. PMID 10220346 DOI: 10.1021/bi982910n |
0.454 |
|
| 1993 |
Hughey CT, Barbour KW, Berger FG, Berger SH. Genetic variation in thymidylate synthase confers resistance to 5-fluorodeoxyuridine. Advances in Experimental Medicine and Biology. 339: 67-76. PMID 8178730 DOI: 10.1007/978-1-4615-2488-5_8 |
0.389 |
|
| 1988 |
Berger SH, Davis ST, Barbour KW, Berger FG. The role of thymidylate synthase in the response to fluoropyrimidine-folinic acid combinations. Advances in Experimental Medicine and Biology. 244: 59-69. PMID 2977716 DOI: 10.1007/978-1-4684-5607-3_6 |
0.329 |
|
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