| Year |
Citation |
Score |
| 2018 |
Volpe DA, Qosa H. Challenges with the precise prediction of ABC-transporter interactions for improved drug discovery. Expert Opinion On Drug Discovery. 13: 697-707. PMID 29943645 DOI: 10.1080/17460441.2018.1493454 |
0.354 |
|
| 2016 |
Qosa H, Kaddoumi A. Effect of mouse strain as a background for Alzheimer's disease models on the clearance of amyloid-β. Journal of Systems and Integrative Neuroscience. 2: 135-140. PMID 27478623 DOI: 10.15761/JSIN.1000123 |
0.655 |
|
| 2016 |
Qosa H, Mohamed LA, Alqahtani S, Abuasal BS, Hill RA, Kaddoumi A. Transporters as Drug Targets in Neurological Diseases. Clinical Pharmacology and Therapeutics. PMID 27447939 DOI: 10.1002/Cpt.435 |
0.597 |
|
| 2016 |
Qosa H, Mohamed LA, Al Rihani SB, Batarseh YS, Duong QV, Keller JN, Kaddoumi A. High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity. Journal of Alzheimer's Disease : Jad. PMID 27392852 DOI: 10.3233/Jad-151179 |
0.665 |
|
| 2016 |
Qosa H, Lichter J, Sarlo M, Markandaiah SS, McAvoy K, Richard JP, Jablonski MR, Maragakis NJ, Pasinelli P, Trotti D. Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis. Glia. PMID 27158936 DOI: 10.1002/Glia.23003 |
0.395 |
|
| 2015 |
Qosa H, Batarseh YS, Mohyeldin MM, El Sayed KA, Keller JN, Kaddoumi A. Oleocanthal Enhances Amyloid-β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model. Acs Chemical Neuroscience. PMID 26348065 DOI: 10.1021/Acschemneuro.5B00190 |
0.71 |
|
| 2015 |
Qosa H, Mohamed LA, Batarseh YS, Alqahtani S, Ibrahim B, LeVine H, Keller JN, Kaddoumi A. Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice. The Journal of Nutritional Biochemistry. PMID 26344778 DOI: 10.1016/J.Jnutbio.2015.07.022 |
0.689 |
|
| 2015 |
Qosa H, Miller DS, Pasinelli P, Trotti D. Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders. Brain Research. PMID 26187753 DOI: 10.1016/J.Brainres.2015.07.005 |
0.433 |
|
| 2015 |
Alqahtani S, Qosa H, Primeaux B, Kaddoumi A. Orlistat limits cholesterol intestinal absorption by Niemann-pick C1-like 1 (NPC1L1) inhibition. European Journal of Pharmacology. 762: 263-9. PMID 26048312 DOI: 10.1016/J.Ejphar.2015.05.060 |
0.572 |
|
| 2015 |
Mohamed LA, Qosa H, Kaddoumi A. Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats. Acs Chemical Neuroscience. 6: 725-36. PMID 25782004 DOI: 10.1021/Acschemneuro.5B00040 |
0.709 |
|
| 2014 |
Qosa H, LeVine H, Keller JN, Kaddoumi A. Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model. Biochimica Et Biophysica Acta. 1842: 1806-15. PMID 24997450 DOI: 10.1016/J.Bbadis.2014.06.029 |
0.696 |
|
| 2014 |
Qosa H, Abuasal BS, Romero IA, Weksler B, Couraud PO, Keller JN, Kaddoumi A. Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling. Neuropharmacology. 79: 668-78. PMID 24467845 DOI: 10.1016/J.Neuropharm.2014.01.023 |
0.707 |
|
| 2013 |
Abuznait AH, Qosa H, Busnena BA, El Sayed KA, Kaddoumi A. Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies. Acs Chemical Neuroscience. 4: 973-82. PMID 23414128 DOI: 10.1021/Cn400024Q |
0.716 |
|
| 2012 |
Abuasal BS, Qosa H, Sylvester PW, Kaddoumi A. Comparison of the intestinal absorption and bioavailability of γ-tocotrienol and α-tocopherol: in vitro, in situ and in vivo studies. Biopharmaceutics & Drug Disposition. 33: 246-56. PMID 22528033 DOI: 10.1002/Bdd.1790 |
0.564 |
|
| 2012 |
Qosa H, Abuznait AH, Hill RA, Kaddoumi A. Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 151-65. PMID 22504320 DOI: 10.3233/Jad-2012-120319 |
0.709 |
|
| 2011 |
Abuznait AH, Qosa H, O'Connell ND, Akbarian-Tefaghi J, Sylvester PW, El Sayed KA, Kaddoumi A. Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 49: 2765-72. PMID 21851848 DOI: 10.1016/J.Fct.2011.08.004 |
0.574 |
|
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