Clinton E. Canal - Publications

Affiliations: 
University of Illinois, Urbana, IL, United States 
Area:
Amygdala, Memory Modulation, Norepinephrine, Dopamine, Serotonin

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Canal CE, Felsing DE, Liu Y, Zhu W, Wood JT, Perry CK, Vemula R, Booth RG. An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models. Acs Chemical Neuroscience. PMID 26011730 DOI: 10.1021/acschemneuro.5b00099  1
2015 Sakhuja R, Kondabolu K, Córdova-Sintjago T, Travers S, Vincek AS, Kim MS, Abboud KA, Fang L, Sun Z, Canal CE, Booth RG. Novel 4-substituted-N,N-dimethyltetrahydronaphthalen-2-amines: synthesis, affinity, and in silico docking studies at serotonin 5-HT2-type and histamine H1 G protein-coupled receptors. Bioorganic & Medicinal Chemistry. 23: 1588-600. PMID 25703249 DOI: 10.1016/j.bmc.2015.01.060  1
2014 Canal CE, Morgan D, Felsing D, Kondabolu K, Rowland NE, Robertson KL, Sakhuja R, Booth RG. A novel aminotetralin-type serotonin (5-HT) 2C receptor-specific agonist and 5-HT2A competitive antagonist/5-HT2B inverse agonist with preclinical efficacy for psychoses. The Journal of Pharmacology and Experimental Therapeutics. 349: 310-8. PMID 24563531 DOI: 10.1124/jpet.113.212373  1
2013 Canal CE, Cordova-Sintjago T, Liu Y, Kim MS, Morgan D, Booth RG. Molecular pharmacology and ligand docking studies reveal a single amino acid difference between mouse and human serotonin 5-HT2A receptors that impacts behavioral translation of novel 4-phenyl-2-dimethylaminotetralin ligands. The Journal of Pharmacology and Experimental Therapeutics. 347: 705-16. PMID 24080681 DOI: 10.1124/jpet.113.208637  1
2013 Canal CE, Booth RG, Morgan D. Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model. Neuropharmacology. 70: 112-21. PMID 23353901 DOI: 10.1016/j.neuropharm.2013.01.007  1
2012 Córdova-Sintjago T, Sakhuja R, Kondabolu K, Canal CE, Booth RG. Molecular Determinants for Ligand Binding at Serotonin 5-HT2A and 5-HT2C GPCRs: Experimental Affinity Results Analyzed by Molecular Modeling and Ligand Docking Studies. International Journal of Quantum Chemistry. 112: 3807-3814. PMID 23913978 DOI: 10.1002/qua.24237  1
2012 Canal CE, Morgan D. Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model. Drug Testing and Analysis. 4: 556-76. PMID 22517680 DOI: 10.1002/dta.1333  1
2012 Córdova-Sintjago T, Villa N, Canal C, Booth R. Human serotonin 5-HT2C G protein-coupled receptor homology model from the β2 adrenoceptor structure: Ligand docking and mutagenesis studies International Journal of Quantum Chemistry. 112: 140-149. DOI: 10.1002/qua.23231  1
2011 Canal CE, Cordova-Sintjago TC, Villa NY, Fang LJ, Booth RG. Drug discovery targeting human 5-HT(2C) receptors: residues S3.36 and Y7.43 impact ligand-binding pocket structure via hydrogen bond formation. European Journal of Pharmacology. 673: 1-12. PMID 22020288 DOI: 10.1016/j.ejphar.2011.10.006  1
2011 Sadowski RN, Canal CE, Gold PE. Lidocaine attenuates anisomycin-induced amnesia and release of norepinephrine in the amygdala. Neurobiology of Learning and Memory. 96: 136-42. PMID 21453778 DOI: 10.1016/j.nlm.2011.03.007  1
2010 Olaghere da Silva UB, Morabito MV, Canal CE, Airey DC, Emeson RB, Sanders-Bush E. Impact of RNA editing on functions of the serotonin 2C receptor in vivo. Frontiers in Neuroscience. 4: 26. PMID 20582266 DOI: 10.3389/neuro.23.001.2010  1
2010 Canal CE, Olaghere da Silva UB, Gresch PJ, Watt EE, Sanders-Bush E, Airey DC. The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen. Psychopharmacology. 209: 163-74. PMID 20165943 DOI: 10.1007/s00213-010-1784-0  1
2009 Canal CE, Mahautmr KC, Cao C, Sanders-Bush E, Airey DC. RNA editing of the serotonin 2C receptor and expression of Galpha(q) protein: genetic mouse models do not support a role for regulation or compensation. Journal of Neurochemistry. 108: 1136-42. PMID 19154337 DOI: 10.1111/j.1471-4159.2008.05852.x  1
2008 Canal CE, Chang Q, Gold PE. Intra-amygdala injections of CREB antisense impair inhibitory avoidance memory: role of norepinephrine and acetylcholine. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 677-86. PMID 18772255 DOI: 10.1101/lm.904308  1
2007 Canal CE, Gold PE. Different temporal profiles of amnesia after intra-hippocampus and intra-amygdala infusions of anisomycin. Behavioral Neuroscience. 121: 732-41. PMID 17663598 DOI: 10.1037/0735-7044.121.4.732  1
2007 Canal CE, Chang Q, Gold PE. Amnesia produced by altered release of neurotransmitters after intraamygdala injections of a protein synthesis inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 104: 12500-5. PMID 17640910 DOI: 10.1073/pnas.0705195104  1
2006 McNay EC, Canal CE, Sherwin RS, Gold PE. Modulation of memory with septal injections of morphine and glucose: effects on extracellular glucose levels in the hippocampus. Physiology & Behavior. 87: 298-303. PMID 16343563 DOI: 10.1016/j.physbeh.2005.10.016  1
2005 Canal CE, Stutz SJ, Gold PE. Glucose injections into the dorsal hippocampus or dorsolateral striatum of rats prior to T-maze training: modulation of learning rates and strategy selection. Learning & Memory (Cold Spring Harbor, N.Y.). 12: 367-74. PMID 16027177 DOI: 10.1101/lm.88205  1
2005 Canal CE, McNay EC, Gold PE. Increases in extracellular fluid glucose levels in the rat hippocampus following an anesthetic dose of pentobarbital or ketamine-xylazine: an in vivo microdialysis study. Physiology & Behavior. 84: 245-50. PMID 15708776 DOI: 10.1016/j.physbeh.2004.11.009  1
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