| Year |
Citation |
Score |
| 2022 |
Soave C, Ducker C, Kim S, Strahl T, Rosati R, Huang Y, Shaw P, Ratnam M. Identification of ELK1 interacting peptide segments in the androgen receptor. The Biochemical Journal. PMID 35781489 DOI: 10.1042/BCJ20220297 |
0.379 |
|
| 2020 |
Rosati R, Oppat K, Huang Y, Kim S, Ratnam M. Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models. Bmc Cancer. 20: 512. PMID 32493230 DOI: 10.1186/s12885-020-07002-0 |
0.308 |
|
| 2019 |
Pardy L, Rosati R, Soave C, Huang Y, Kim S, Ratnam M. The ternary complex factor protein ELK1 is an independent prognosticator of disease recurrence in prostate cancer. The Prostate. PMID 31794091 DOI: 10.1002/pros.23932 |
0.385 |
|
| 2018 |
Patki M, McFall T, Rosati R, Huang Y, Malysa A, Polin L, Fielder A, Wilson MR, Lonardo F, Back J, Li J, Matherly LH, Bepler G, Ratnam M. Chronic p27 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor. Scientific Reports. 8: 16006. PMID 30375484 DOI: 10.1038/S41598-018-34475-8 |
0.735 |
|
| 2018 |
Rosati R, Polin LA, Ducker C, Li J, Bao X, Selvakumar D, Kim S, Xhabija B, Larsen M, McFall T, Huang Y, Kidder BL, Fribley A, Saxton J, Kakuta H, ... ... Ratnam M, et al. Strategy for Tumor Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30185422 DOI: 10.1158/1078-0432.Ccr-18-0982 |
0.464 |
|
| 2018 |
Frontera ED, Khansa RM, Schalk DL, Leakan LE, Guerin-Edbauer TJ, Ratnam M, Gorski DH, Speyer CL. IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells. Breast Cancer Research and Treatment. PMID 30155754 DOI: 10.1007/s10549-018-4941-5 |
0.314 |
|
| 2016 |
Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, Kidder BL, Shaw PE, Ratnam M. The Amino-terminal Domain of the Androgen Receptor Co-opts ERK Docking Sites in ELK1 to Induce Sustained Gene Activation that Supports Prostate Cancer Cell Growth. The Journal of Biological Chemistry. PMID 27793987 DOI: 10.1074/Jbc.M116.745596 |
0.793 |
|
| 2016 |
Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z. Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease HSP90 and the Androgen Receptor Levels and Inhibit Viability in Enzalutamide Resistant C4-2 Prostate Cancer Cells. Molecular Pharmacology. PMID 27382012 DOI: 10.1124/Mol.116.103416 |
0.77 |
|
| 2016 |
Patki M, Huang Y, Ratnam M. Restoration of the cellular secretory milieu overrides androgen dependence of in vivo generated castration resistant prostate cancer cells overexpressing the androgen receptor. Biochemical and Biophysical Research Communications. PMID 27179779 DOI: 10.1016/J.Bbrc.2016.05.058 |
0.807 |
|
| 2015 |
McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. Oncotarget. 6: 33146-64. PMID 26356672 DOI: 10.18632/Oncotarget.5082 |
0.752 |
|
| 2015 |
Patki M, Salazar Md, Trumbly R, Ratnam M. Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells. Biochemical and Biophysical Research Communications. 457: 404-11. PMID 25582774 DOI: 10.1016/J.Bbrc.2015.01.004 |
0.746 |
|
| 2015 |
McFall T, Patki M, Rosati R, Ratnam M. Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges Oncotarget. 6: 33146-33164. DOI: 10.18632/oncotarget.5082 |
0.756 |
|
| 2015 |
Patki M, D'Alincourt Salazar M, Trumbly R, Ratnam M. Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells Biochemical and Biophysical Research Communications. 457: 404-411. DOI: 10.1016/j.bbrc.2015.01.004 |
0.761 |
|
| 2014 |
Patki M, Gadgeel S, Huang Y, McFall T, Shields AF, Matherly LH, Bepler G, Ratnam M. Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 519-526. PMID 24736075 DOI: 10.1097/Jto.0000000000000111 |
0.743 |
|
| 2014 |
Shen M, Zhang Z, Ratnam M, Dou QP. The interplay of AMP-activated protein kinase and androgen receptor in prostate cancer cells. Journal of Cellular Physiology. 229: 688-95. PMID 24129850 DOI: 10.1002/jcp.24494 |
0.47 |
|
| 2013 |
Patki M, Chari V, Sivakumaran S, Gonit M, Trumbly R, Ratnam M. The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells Journal of Biological Chemistry. 288: 11047-11065. PMID 23426362 DOI: 10.1074/Jbc.M112.438473 |
0.719 |
|
| 2013 |
Ratnam M, Patki M, Gonit M, Trumbly R. Mechanisms of ARE-independent gene activation by the androgen receptor in prostate cancer cells: Potential targets for better intervention strategies Androgen-Responsive Genes in Prostate Cancer: Regulation, Function and Clinical Applications. 2147483647: 85-100. DOI: 10.1007/978-1-4614-6182-1_6 |
0.79 |
|
| 2011 |
Gonit M, Zhang J, d'Alincourt Salazar M, Cui H, Shatnawi A, Trumbly R, Ratnam M. Hormone depletion-insensitivity of prostate cancer cells is supported by the AR without binding to classical response elements Molecular Endocrinology. 25: 621-634. PMID 21330406 DOI: 10.1210/Me.2010-0409 |
0.836 |
|
| 2011 |
Salazar MD, Ratnam M, Patki M, Kisovic I, Trumbly R, Iman M. During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein Breast Cancer Research. 13. PMID 21299862 DOI: 10.1186/Bcr2827 |
0.76 |
|
| 2010 |
Sivakumaran S, Zhang J, Kelley KM, Gonit M, Hao H, Ratnam M. Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα. The Journal of Steroid Biochemistry and Molecular Biology. 122: 333-40. PMID 20817090 DOI: 10.1016/j.jsbmb.2010.08.008 |
0.741 |
|
| 2010 |
Zhang J, Gonit M, Salazar MD, Shatnawi A, Shemshedini L, Trumbly R, Ratnam M. C/EBPα redirects androgen receptor signaling through a unique bimodal interaction Oncogene. 29: 723-738. PMID 19901962 DOI: 10.1038/Onc.2009.373 |
0.826 |
|
| 2009 |
Elnakat H, Gonit M, Salazar MDA, Zhang J, Basrur V, Gunning W, Kamen B, Ratnam M. Regulation of folate receptor internalization by protein kinase C Biochemistry. 48: 8249-8260. PMID 19639961 DOI: 10.1021/Bi900565T |
0.792 |
|
| 2008 |
Zhang J, Wilkinson JE, Gonit M, Keck R, Selman S, Ratnam M. Expression and sub-cellular localization of the CCAAT/enhancer binding protein α in relation to postnatal development and malignancy of the prostate Prostate. 68: 1206-1214. PMID 18481268 DOI: 10.1002/Pros.20779 |
0.812 |
|
| 2007 |
Lu Y, Wu J, Wu J, Gonit M, Yang X, Lee A, Xiang G, Li H, Liu S, Marcucci G, Ratnam M, Lee RJ. Role of formulation composition in folate receptor-targeted liposomal doxorubicin delivery to acute myelogenous leukemia cells. Molecular Pharmaceutics. 4: 707-12. PMID 17708654 DOI: 10.1021/mp070058l |
0.765 |
|
| 2007 |
Blaser BW, Gonit M, Qi H, Shatnawi A, Guimond M, Lee RJ, Ratnam M. Induction of folate receptor type β in a bone marrow engraftment model of acute myelogenous leukemia [22] Leukemia. 21: 2233-2235. PMID 17554378 DOI: 10.1038/Sj.Leu.2404786 |
0.749 |
|
| 2006 |
Elnakat H, Ratnam M. Role of folate receptor genes in reproduction and related cancers Frontiers in Bioscience. 11: 506-519. PMID 16146749 DOI: 10.2741/1815 |
0.37 |
|
| 2005 |
Tran T, Shatnawi A, Zheng X, Kelley KM, Ratnam M. Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: a promising means to improved tumor detection and targeting. Cancer Research. 65: 4431-41. PMID 15899836 DOI: 10.1158/0008-5472.CAN-04-2890 |
0.315 |
|
| 2004 |
Elnakat H, Ratnam M. Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Advanced Drug Delivery Reviews. 56: 1067-84. PMID 15094207 DOI: 10.1016/j.addr.2004.01.001 |
0.305 |
|
| 1987 |
Lindstrom J, Criado M, Ratnam M, Whiting P, Ralston S, Rivier J, Sarin V, Sargent P. Using monoclonal antibodies to determine the structures of acetylcholine receptors from electric organs, muscles, and neurons Annals of the New York Academy of Sciences. 505: 208-225. PMID 2446548 DOI: 10.1111/J.1749-6632.1987.Tb51293.X |
0.407 |
|
| 1986 |
Ratnam M, Gullick W, Spiess J, Wan K, Criado M, Lindstrom J. Structural heterogeneity of the alpha subunits of the nicotinic acetylcholine receptor in relation to agonist affinity alkylation and antagonist binding. Biochemistry. 25: 4268-75. PMID 3756139 DOI: 10.1021/Bi00363A014 |
0.43 |
|
| 1986 |
Ratnam M, Sargent PB, Sarin V, Fox JL, Nguyen DL, Rivier J, Criado M, Lindstrom J. Location of antigenic determinants on primary sequences of subunits of nicotinic acetylcholine receptor by peptide mapping. Biochemistry. 25: 2621-32. PMID 2424498 DOI: 10.1021/Bi00357A051 |
0.438 |
|
| 1985 |
Lindstrom J, Hochschwender S, Wan K, Ratnam M, Criado M. Use of monoclonal antibodies in exploring the structure of the acetylcholine receptor Biochemical Society Transactions. 13: 14-16. PMID 3996735 DOI: 10.1042/Bst0130014 |
0.437 |
|
| 1984 |
Ratnam M, Lindstrom J. Structural features of the nicotinic acetylcholine receptor revealed by antibodies to synthetic peptides. Biochemical and Biophysical Research Communications. 122: 1225-1233. PMID 6206851 DOI: 10.1016/0006-291X(84)91223-3 |
0.481 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2007 |
Hao H, d'Alincourt-Salazar M, Kelley KM, Shatnawi A, Mukherjee S, Shah YM, Ratnam M. Estrogen-induced and TAFII30-mediated gene repression by direct recruitment of the estrogen receptor and co-repressors to the core promoter and its reversal by tamoxifen. Oncogene. 26: 7872-84. PMID 17599049 DOI: 10.1038/sj.onc.1210592 |
0.297 |
|
| 2022 |
Ducker C, Ratnam M, Shaw PE, Layfield R. Comparative analysis of protein expression systems and PTM landscape in the study of transcription factor ELK-1. Protein Expression and Purification. 203: 106216. PMID 36528218 DOI: 10.1016/j.pep.2022.106216 |
0.294 |
|
| 2023 |
Soave C, Ducker C, Islam N, Kim S, Yurgelevic S, Nicely NI, Pardy L, Huang Y, Shaw P, Auner G, Dickson A, Ratnam M. . Molecular Pharmacology. PMID 36720643 DOI: 10.1124/molpharm.122.000589 |
0.292 |
|
| 2013 |
Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE. Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proceedings of the National Academy of Sciences of the United States of America. 110: 15180-8. PMID 23934049 DOI: 10.1073/Pnas.1308827110 |
0.288 |
|
| 2003 |
Kelley KM, Rowan BG, Ratnam M. Modulation of the folate receptor alpha gene by the estrogen receptor: mechanism and implications in tumor targeting. Cancer Research. 63: 2820-8. PMID 12782587 |
0.286 |
|
| 2020 |
Purrington KS, Gorski D, Simon MS, Hastert TA, Kim S, Rosati R, Schwartz AG, Ratnam M. Racial differences in estrogen receptor staining levels and implications for treatment and survival among estrogen receptor positive, HER2-negative invasive breast cancers. Breast Cancer Research and Treatment. PMID 32236827 DOI: 10.1007/s10549-020-05607-4 |
0.283 |
|
| 2007 |
Shatnawi A, Tran T, Ratnam M. R5020 and RU486 act as progesterone receptor agonists to enhance Sp1/Sp4-dependent gene transcription by an indirect mechanism Molecular Endocrinology. 21: 635-650. PMID 17192405 DOI: 10.1210/me.2006-0274 |
0.28 |
|
| 2021 |
Block CJ, Mitchell AV, Wu L, Glassbrook J, Craig D, Chen W, Dyson G, DeGracia D, Polin L, Ratnam M, Gibson H, Wu G. RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA. Oncogene. PMID 34608266 DOI: 10.1038/s41388-021-02030-x |
0.27 |
|
| 2019 |
Block CJ, Dyson G, Campeanu IJ, Watza D, Ratnam M, Wu G. A stroma-corrected ZEB1 transcriptional signature is inversely associated with antitumor immune activity in breast cancer. Scientific Reports. 9: 17807. PMID 31780722 DOI: 10.1038/s41598-019-54282-z |
0.267 |
|
| 2019 |
Farran B, Albayrak S, Abrams J, Tainsky MA, Levin NK, Morris R, Matherly LH, Ratnam M, Winer I. Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance. Cancer Medicine. PMID 30761774 DOI: 10.1002/Cam4.1944 |
0.258 |
|
| 2003 |
Hao H, Qi H, Ratnam M. Modulation of the folate receptor type beta gene by coordinate actions of retinoic acid receptors at activator Sp1/ets and repressor AP-1 sites. Blood. 101: 4551-60. PMID 12543860 DOI: 10.1182/blood-2002-10-3174 |
0.254 |
|
| 2006 |
Qi H, Ratnam M. Synergistic induction of folate receptor β by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: Mechanism and utility in enhancing selective growth inhibition by antifolates Cancer Research. 66: 5875-5882. PMID 16740727 DOI: 10.1158/0008-5472.CAN-05-4048 |
0.252 |
|
| 2007 |
Salazar MDA, Ratnam M. The folate receptor: What does it promise in tissue-targeted therapeutics? Cancer and Metastasis Reviews. 26: 141-152. PMID 17333345 DOI: 10.1007/s10555-007-9048-0 |
0.252 |
|
| 1994 |
Ross JF, Chaudhuri PK, Ratnam M. Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications. Cancer. 73: 2432-43. PMID 7513252 DOI: 10.1002/1097-0142(19940501)73:9<2432::aid-cncr2820730929>3.0.co;2-s |
0.249 |
|
| 1999 |
Wu M, Gunning W, Ratnam M. Expression of folate receptor type alpha in relation to cell type, malignancy, and differentiation in ovary, uterus, and cervix. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 8: 775-82. PMID 10498396 |
0.246 |
|
| 1997 |
Wu M, Fan J, Gunning W, Ratnam M. Clustering of GPI-anchored folate receptor independent of both cross-linking and association with caveolin. The Journal of Membrane Biology. 159: 137-47. PMID 9307440 DOI: 10.1007/s002329900277 |
0.243 |
|
| 2017 |
Albano-Aluquin S, Malysz J, Aluquin VR, Ratnam M, Olsen N. An immunohistochemical analysis of folate receptor beta expression and distribution in giant cell arteritis - a pilot study. American Journal of Clinical and Experimental Immunology. 6: 107-114. PMID 29348986 |
0.24 |
|
| 2017 |
McFall T, McKnight B, Rosati R, Kim S, Huang Y, Viola-Villegas N, Ratnam M. Progesterone Receptor A Promotes Invasiveness and Metastasis of Luminal Breast Cancer by Suppressing Regulation of Critical Micro RNAs by Estrogen. The Journal of Biological Chemistry. PMID 29162724 DOI: 10.1074/jbc.M117.812438 |
0.238 |
|
| 2000 |
Wang H, Zheng X, Behm FG, Ratnam M. Differentiation-independent retinoid induction of folate receptor type beta, a potential tumor target in myeloid leukemia. Blood. 96: 3529-36. PMID 11071651 |
0.238 |
|
| 1994 |
Shen F, Ross JF, Wang X, Ratnam M. Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity. Biochemistry. 33: 1209-15. PMID 8110752 DOI: 10.1021/BI00171A021 |
0.235 |
|
| 2003 |
Ratnam M, Hao H, Zheng X, Wang H, Qi H, Lee R, Pan X. Receptor induction and targeted drug delivery: a new antileukaemia strategy. Expert Opinion On Biological Therapy. 3: 563-74. PMID 12831362 DOI: 10.1517/14712598.3.4.563 |
0.235 |
|
| 2013 |
Jetson R, Malik N, Luniwal A, Chari V, Ratnam M, Erhardt P. Practical synthesis of a chromene analog for use as a retinoic acid receptor alpha antagonist lead compound European Journal of Medicinal Chemistry. 63: 104-108. PMID 23474897 DOI: 10.1016/J.Ejmech.2013.02.012 |
0.224 |
|
| 1996 |
Wang X, Jansen G, Fan J, Kohler WJ, Ross JF, Schornagel J, Ratnam M. Variant GPI structure in relation to membrane-associated functions of a murine folate receptor. Biochemistry. 35: 16305-12. PMID 8973205 DOI: 10.1021/bi961098q |
0.221 |
|
| 2020 |
Samaniego R, Domínguez-Soto Á, Ratnam M, Matsuyama T, Sánchez-Mateos P, Corbí ÁL, Puig-Kröger A. Folate Receptor β (FRβ) Expression in Tissue-Resident and Tumor-Associated Macrophages Associates with and Depends on the Expression of PU.1. Cells. 9. PMID 32532019 DOI: 10.3390/cells9061445 |
0.22 |
|
| 1998 |
Wang H, Ross JF, Ratnam M. Structure and regulation of a polymorphic gene encoding folate receptor type gamma/gamma'. Nucleic Acids Research. 26: 2132-42. PMID 9547271 DOI: 10.1093/nar/26.9.2132 |
0.219 |
|
| 2022 |
Parajuli P, Rosati R, Mamdani H, Wright RE, Hussain Z, Naeem A, Dzinic S, Polin L, Gavande NS, Ratnam M. Senescence-associated secretory proteins induced in lung adenocarcinoma by extended treatment with dexamethasone enhance migration and activation of lymphocytes. Cancer Immunology, Immunotherapy : Cii. PMID 36434273 DOI: 10.1007/s00262-022-03332-z |
0.211 |
|
| 1999 |
Ross JF, Wang H, Behm FG, Mathew P, Wu M, Booth R, Ratnam M. Folate receptor type beta is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia. Cancer. 85: 348-57. PMID 10023702 DOI: 10.1002/(sici)1097-0142(19990115)85:2<348::aid-cncr12>3.0.co;2-4 |
0.208 |
|
| 2016 |
Holowatyj AN, Ruterbusch JJ, Ratnam M, Gorski DH, Cote ML. HER2 status and disparities in luminal breast cancers. Cancer Medicine. PMID 27250116 DOI: 10.1002/Cam4.757 |
0.206 |
|
| 1992 |
Wang X, Shen F, Freisheim JH, Gentry LE, Ratnam M. Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates. Biochemical Pharmacology. 44: 1898-901. PMID 1449544 DOI: 10.1016/0006-2952(92)90089-2 |
0.202 |
|
| 1995 |
Shen F, Wu M, Ross JF, Miller D, Ratnam M. Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: protein characterization and cell type specificity. Biochemistry. 34: 5660-5. PMID 7727426 DOI: 10.1021/bi00016a042 |
0.197 |
|
| 1997 |
Shen F, Wang H, Zheng X, Ratnam M. Expression levels of functional folate receptors alpha and beta are related to the number of N-glycosylated sites. The Biochemical Journal. 327: 759-64. PMID 9581553 DOI: 10.1042/bj3270759 |
0.196 |
|
| 2018 |
McHugh C, Thipparthi MR, Lawhorn-Crews JM, Polin L, Gadgeel S, Akoury J, Mangner TJ, Douglas KA, Li J, Ratnam M, Shields AF. Utilizing radiolabeled 3'-deoxy-3'-[F]fluorothymidine with positron emission tomography to monitor the effect of dexamethasone on non-small cell lung cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29674424 DOI: 10.2967/Jnumed.117.207258 |
0.194 |
|
| 2009 |
Van Der Heijden JW, Oerlemans R, Dijkmans BAC, Qi H, Van Der Laken CJ, Lems WF, Jackman AL, Kraan MC, Tak PP, Ratnam M, Jansen G. Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients Arthritis and Rheumatism. 60: 12-21. PMID 19116913 DOI: 10.1002/art.24219 |
0.191 |
|
| 2002 |
Pan XQ, Zheng X, Shi G, Wang H, Ratnam M, Lee RJ. Strategy for the treatment of acute myelogenous leukemia based on folate receptor beta-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid. Blood. 100: 594-602. PMID 12091353 DOI: 10.1182/BLOOD.V100.2.594 |
0.19 |
|
| 2019 |
Albano-Aluquin S, Malysz J, Kidacki M, Ratnam M, Olsen NJ. An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis. Journal of Visualized Experiments : Jove. PMID 30799840 DOI: 10.3791/58713 |
0.189 |
|
| 2003 |
Kelley KM, Wang H, Ratnam M. Dual regulation of ets-activated gene expression by SP1. Gene. 307: 87-97. PMID 12706891 DOI: 10.1016/S0378-1119(03)00445-1 |
0.179 |
|
| 1997 |
Wang J, Shen F, Yan W, Wu M, Ratnam M. Proteolysis of the carboxyl-terminal GPI signal independent of GPI modification as a mechanism for selective protein secretion. Biochemistry. 36: 14583-92. PMID 9398177 DOI: 10.1021/bi970845w |
0.174 |
|
| 2003 |
Zheng X, Kelley K, Elnakat H, Yan W, Dorn T, Ratnam M. mRNA instability in the nucleus due to a novel open reading frame element is a major determinant of the narrow tissue specificity of folate receptor alpha. Molecular and Cellular Biology. 23: 2202-12. PMID 12612090 DOI: 10.1128/MCB.23.6.2202-2212.2003 |
0.171 |
|
| 1992 |
Freisheim JH, Ratnam M, McAlinden TP, Prasad KM, Williams FE, Westerhof GR, Schornagel JH, Jansen G. Molecular events in the membrane transport of methotrexate in human CCRF-CEM leukemia cell lines. Advances in Enzyme Regulation. 32: 17-31. PMID 1323203 DOI: 10.1016/0065-2571(92)90006-L |
0.171 |
|
| 2010 |
Li H, Lu Y, Piao L, Wu J, Liu S, Marcucci G, Ratnam M, Lee RJ. Targeting human clonogenic acute myelogenous leukemia cells via folate conjugated liposomes combined with receptor modulation by all-trans retinoic acid International Journal of Pharmaceutics. 402: 57-63. PMID 20883757 DOI: 10.1016/j.ijpharm.2010.09.019 |
0.167 |
|
| 2016 |
Wilson MR, Hou Z, Yang S, Polin L, Kushner J, White K, Huang J, Ratnam M, Gangjee A, Matherly LH. Targeting Non-Squamous Non-Small Cell Lung Cancer Via the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]Pyrimidine Thienoyl Antifolates. Molecular Pharmacology. PMID 26837243 DOI: 10.1124/Mol.115.102798 |
0.162 |
|
| 1986 |
Ratnam M, Nguyen DL, Rivier J, Sargent PB, Lindstrom J. Transmembrane topography of nicotinic acetylcholine receptor: immunochemical tests contradict theoretical predictions based on hydrophobicity profiles. Biochemistry. 25: 2633-43. PMID 3718969 |
0.159 |
|
| 1999 |
Wang J, Maziarz K, Ratnam M. Recognition of the carboxyl-terminal signal for GPI modification requires translocation of its hydrophobic domain across the ER membrane. Journal of Molecular Biology. 286: 1303-10. PMID 10064698 DOI: 10.1006/jmbi.1999.2584 |
0.151 |
|
| 1999 |
Maziarz KM, Monaco HL, Shen F, Ratnam M. Complete mapping of divergent amino acids responsible for differential ligand binding of folate receptors alpha and beta. The Journal of Biological Chemistry. 274: 11086-91. PMID 10196192 DOI: 10.1074/jbc.274.16.11086 |
0.146 |
|
| 1989 |
Freisheim JH, Price EM, Ratnam M. Folate coenzyme and antifolate transport proteins in normal and neoplastic cells. Advances in Enzyme Regulation. 29: 13-26. PMID 2561247 DOI: 10.1016/0065-2571(89)90091-5 |
0.145 |
|
| 1998 |
Yan W, Shen F, Dillon B, Ratnam M. The hydrophobic domains in the carboxyl-terminal signal for GPI modification and in the amino-terminal leader peptide have similar structural requirements. Journal of Molecular Biology. 275: 25-33. PMID 9451436 DOI: 10.1006/jmbi.1997.1447 |
0.143 |
|
| 1988 |
Freisheim JH, Ratnam M, Smith PL, Delcamp TJ, Price EM. Photoaffinity analogues of methotrexate as folate antagonist binding probes. Advances in Enzyme Regulation. 27: 15-29. PMID 3250227 DOI: 10.1016/0065-2571(88)90006-4 |
0.137 |
|
| 1997 |
Shen F, Zheng X, Wang J, Ratnam M. Identification of amino acid residues that determine the differential ligand specificities of folate receptors alpha and beta. Biochemistry. 36: 6157-63. PMID 9166787 DOI: 10.1021/bi9626564 |
0.135 |
|
| 1995 |
Yan W, Ratnam M. Preferred sites of glycosylphosphatidylinositol modification in folate receptors and constraints in the primary structure of the hydrophobic portion of the signal. Biochemistry. 34: 14594-600. PMID 7578066 DOI: 10.1021/bi00044a039 |
0.127 |
|
| 2002 |
Wang J, Gunning W, Kelley KM, Ratnam M. Evidence for segregation of heterologous GPI-anchored proteins into separate lipid rafts within the plasma membrane. The Journal of Membrane Biology. 189: 35-43. PMID 12202950 DOI: 10.1007/s00232-002-1002-z |
0.125 |
|
| 2009 |
Puig-Kröger A, Sierra-Filardi E, DomÃnguez-Soto A, Samaniego R, Corcuera MT, Gómez-Aguado F, Ratnam M, Sánchez-Mateos P, Corbà AL. Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages. Cancer Research. 69: 9395-403. PMID 19951991 DOI: 10.1158/0008-5472.CAN-09-2050 |
0.124 |
|
| 2004 |
Pan XQ, Lee RJ, Ratnam M. Penetration into solid tumor tissue of fluorescent latex microspheres: a mimic of liposome particles. Anticancer Research. 24: 3005-8. PMID 15517908 |
0.114 |
|
| 2012 |
Jaiswal N, Saraswat S, Ratnam M, Isailovic D. Analysis of folate binding protein N-linked glycans by mass spectrometry. Journal of Proteome Research. 11: 1551-60. PMID 22191536 DOI: 10.1021/Pr2006044 |
0.11 |
|
| 1989 |
Ratnam M, Marquardt H, Duhring JL, Freisheim JH. Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA. Biochemistry. 28: 8249-54. PMID 2605182 DOI: 10.1021/bi00446a042 |
0.101 |
|
| 1990 |
Tan XH, Huang SM, Ratnam M, Thompson PD, Freisheim JH. The importance of loop region residues 40-46 in human dihydrofolate reductase as revealed by site-directed mutagenesis. The Journal of Biological Chemistry. 265: 8027-32. PMID 2186034 |
0.099 |
|
| 1989 |
Freisheim JH, Ratnam M, Price EM. Photoaffinity and immunological probes of methotrexate transport proteins in drug-sensitive and -resistant leukemia cells. Progress in Clinical and Biological Research. 292: 453-60. PMID 2726921 |
0.099 |
|
| 1993 |
Williams FE, Ratnam M, McAlinden TP, Jansen G, Schornagel JH, Freisheim JH. Transformation of an L-cell line with the DNA coding for the reduced-folate/methotrexate transporter protein from a CCRF-CEM human leukemia cell line. Advances in Experimental Medicine and Biology. 338: 779-82. PMID 8304228 DOI: 10.1007/978-1-4615-2960-6_163 |
0.09 |
|
| 1989 |
Ratnam S, Ratnam M, Cotton RG, Jennings IG, Freisheim JH. Anti-idiotypic antibodies elicited by pterin recognize active site epitopes in dihydrofolate reductases and dihydropteridine reductase. Archives of Biochemistry and Biophysics. 275: 344-53. PMID 2480746 DOI: 10.1016/0003-9861(89)90381-0 |
0.071 |
|
| 1988 |
Ratnam M, Tan X, Prendergast NJ, Smith PL, Freisheim JH. Ligand-induced structural constraints in human dihydrofolate reductase revealed by peptide-specific antibodies Biochemistry. 27: 4800-4804. PMID 3048392 DOI: 10.1021/BI00413A033 |
0.069 |
|
| 1990 |
Tan XH, Ratnam M, Huang SM, Smith PL, Freisheim JH. Mapping the antigenic epitopes of human dihydrofolate reductase by systematic synthesis of peptides on solid supports. The Journal of Biological Chemistry. 265: 8022-6. PMID 1692321 |
0.069 |
|
| 1996 |
Gossett LS, Habeck LL, Gates SB, Andis SL, Worzalla JF, Schultz RM, Mendelsonn LG, Kohler W, Ratnam M, Grindey GB, Shih C. Synthesis and biological evaluation of a new series of dihydrofolate reductase inhibitors based on the 4-(2,6-diamino-5-pyrimidinyl)alkyl-L-glutamic acid structure Bioorganic & Medicinal Chemistry Letters. 6: 473-476. DOI: 10.1016/0960-894X(96)00053-4 |
0.02 |
|
| 2013 |
Jansen G, Weijers K, Blits M, Van Der Heijden J, Gent Y, Al M, Van Der Laken C, Molthoff C, Verweij C, Voskuijl A, Lems W, Scheper R, Peters G, Ratnam M, Aassaraf Y, et al. Folates and antifolates in rheumatoid arthritis Pteridines. 24: 21-26. DOI: 10.1515/pterid-2013-0012 |
0.01 |
|
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