| Year |
Citation |
Score |
| 2020 |
Marden G, Wan Q, Wilks J, Nevin K, Feeney M, Wisniacki N, Trojanowski M, Bujor A, Stawski L, Trojanowska M. The role of the oncostatin M/OSM receptor β axis in activating dermal microvascular endothelial cells in systemic sclerosis. Arthritis Research & Therapy. 22: 179. PMID 32736577 DOI: 10.1186/S13075-020-02266-0 |
0.365 |
|
| 2020 |
Bujor AM, El Adili F, Parvez A, Marden G, Trojanowska M. Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory Effects. Frontiers in Immunology. 11: 800. PMID 32508810 DOI: 10.3389/fimmu.2020.00800 |
0.315 |
|
| 2020 |
Bujor AM, Adili FE, Parvez A, Marden G, Trojanowska M. Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory Effects. Frontiers in Immunology. 11: 800. DOI: 10.3389/Fimmu.2020.00800 |
0.427 |
|
| 2019 |
Huang M, Cai G, Baugh LM, Liu Z, Smith A, Watson M, Popovich D, Zhang T, Stawski LS, Trojanowska M, Georgakoudi I, Black LD, Pioli PA, Whitfield ML, Garlick J. Systemic Sclerosis Dermal Fibroblasts Induce Cutaneous Fibrosis Through LOXL4: New Evidence from 3D Skin-like Tissues. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31705627 DOI: 10.1002/Art.41163 |
0.414 |
|
| 2019 |
Hsu T, Nguyen-Tran HH, Trojanowska M. Active roles of dysfunctional vascular endothelium in fibrosis and cancer. Journal of Biomedical Science. 26: 86. PMID 31656195 DOI: 10.1186/S12929-019-0580-3 |
0.365 |
|
| 2018 |
Yamashita T, Asano Y, Saigusa R, Taniguchi T, Hirabayashi M, Miyagawa T, Nakamura K, Miura S, Yoshizaki A, Trojanowska M, Sato S. Cyclophosphamide pulse therapy normalizes vascular abnormalities in a mouse model of systemic sclerosis vasculopathy. The Journal of Investigative Dermatology. PMID 30508546 DOI: 10.1016/J.Jid.2018.11.016 |
0.348 |
|
| 2018 |
Saigusa R, Asano Y, Taniguchi T, Hirabayashi M, Nakamura K, Miura S, Yamashita T, Takahashi T, Ichimura Y, Toyama T, Yoshizaki A, Trojanowska M, Sato S. Fli1-haploinsufficient dermal fibroblasts promote skin-localized transdifferentiation of Th2-like regulatory T cells. Arthritis Research & Therapy. 20: 23. PMID 29415756 DOI: 10.1186/S13075-018-1521-3 |
0.331 |
|
| 2018 |
Stawski L, Marden G, Trojanowska M. The Activation of Human Dermal Microvascular Cells by Poly(I:C), Lipopolysaccharide, Imiquimod, and ODN2395 Is Mediated by the Fli1/FOXO3A Pathway. Journal of Immunology. 200: 248-259. PMID 29141862 DOI: 10.4049/Jimmunol.1601968 |
0.321 |
|
| 2017 |
Toyama T, Looney AP, Baker BM, Stawski L, Haines P, Simms R, Szymaniak AD, Varelas X, Trojanowska M. Therapeutic targeting of TAZ and YAP by dimethyl fumarate in systemic sclerosis fibrosis. The Journal of Investigative Dermatology. PMID 28870693 DOI: 10.1016/J.Jid.2017.08.024 |
0.4 |
|
| 2017 |
Makino K, Makino T, Stawski L, Lipson KE, Leask A, Trojanowska M. Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis. Arthritis Research & Therapy. 19: 134. PMID 28610597 DOI: 10.1186/S13075-017-1356-3 |
0.373 |
|
| 2017 |
Makino K, Makino T, Stawski L, Mantero JC, Lafyatis R, Simms R, Trojanowska M. Blockade of PDGF receptors by crenolanib has therapeutic effect in patient fibroblasts and in preclinical models of systemic sclerosis. The Journal of Investigative Dermatology. PMID 28433542 DOI: 10.1016/J.Jid.2017.03.032 |
0.439 |
|
| 2017 |
Grzegorzewska AP, Han R, Stawski L, Marden G, Iwamoto M, Trojanowska M. Synergistic Role of Endothelial ERG and FLI1 in Mediating Pulmonary Vascular Homeostasis. American Journal of Respiratory Cell and Molecular Biology. PMID 28248553 DOI: 10.1165/Rcmb.2016-0200Oc |
0.394 |
|
| 2017 |
Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, Ichimura Y, Toyama T, Taniguchi T, Akamata K, Noda S, Yoshizaki A, Tsuruta D, Trojanowska M, Sato S. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. The Journal of Experimental Medicine. PMID 28232470 DOI: 10.1084/Jem.20160247 |
0.41 |
|
| 2017 |
Grzegorzewska AP, Seta F, Han R, Czajka CA, Makino K, Stawski L, Isenberg JS, Browning JL, Trojanowska M. Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways. Scientific Reports. 7: 41605. PMID 28150703 DOI: 10.1038/Srep41605 |
0.33 |
|
| 2017 |
Miura S, Asano Y, Saigusa R, Yamashita T, Nakamura K, Hirabayashi M, Miyagawa T, Yoshizaki A, Trojanowska M, Sato S. 305 Fli1 deficiency alters the phenotype of dermal dendritic cells, promoting the development of dermal fibrosis in bleomycin-treated mice Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.07.500 |
0.302 |
|
| 2017 |
Miyagawa T, Asano Y, Saigusa R, Nakamura K, Hirabayashi M, Yamashita T, Miura S, Taniguchi T, Yoshizaki A, Trojanowska M, Sato S. 298 Fli1-deficient adipocytes promote the spontaneous development of dermal fibrosis and vasculopathy mimicking systemic sclerosis through adipocytes-to-myofibroblast transdifferentiation and defective vasculogenesis Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.07.493 |
0.316 |
|
| 2017 |
Yamashita T, Asano Y, Yoshizaki A, Trojanowska M, Sato S. 892 The combination of bosentan with bFGF accelerates wound healing in endothelial cell-specific Fli1 knockout mice mimicking scleroderma vasculopathy Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.919 |
0.318 |
|
| 2017 |
Saigusa R, Asano Y, Yoshizaki A, Trojanowska M, Sato S. 005 Fli1-deficient B cells induce scleroderma-like vascular disorganization via activating pro-angiogenic gene program in dermal microvascular endothelial cells – A possible role in scleroderma vasculopathy Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.018 |
0.315 |
|
| 2016 |
Yamashita T, Asano Y, Taniguchi T, Nakamura K, Saigusa R, Miura S, Toyama T, Takahashi T, Ichimura Y, Yoshizaki A, Trojanowska M, Sato S. Glycyrrhizin ameliorates fibrosis, vasculopathy, and inflammation in animal models of systemic sclerosis. The Journal of Investigative Dermatology. PMID 27777101 DOI: 10.1016/J.Jid.2016.08.037 |
0.421 |
|
| 2016 |
Kartha VK, Stawski L, Han R, Haines P, Gallagher G, Noonan V, Kukuruzinska M, Monti S, Trojanowska M. PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas. Plos One. 11: e0154645. PMID 27128408 DOI: 10.1371/Journal.Pone.0154645 |
0.337 |
|
| 2015 |
Han R, Pacifici M, Iwamoto M, Trojanowska M. Endothelial Erg expression is required for embryogenesis and vascular integrity. Organogenesis. 11: 75-86. PMID 26061019 DOI: 10.1080/15476278.2015.1031435 |
0.336 |
|
| 2014 |
Stawski L, Haines P, Fine A, Rudnicka L, Trojanowska M. MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis. Plos One. 9: e109763. PMID 25302498 DOI: 10.1371/Journal.Pone.0109763 |
0.385 |
|
| 2014 |
Kudo H, Jinnin M, Asano Y, Trojanowska M, Nakayama W, Inoue K, Honda N, Kajihara I, Makino K, Fukushima S, Ihn H. Decreased interleukin-20 expression in scleroderma skin contributes to cutaneous fibrosis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 1636-47. PMID 24470401 DOI: 10.1002/Art.38380 |
0.337 |
|
| 2014 |
van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, ... ... Trojanowska M, et al. Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. The New England Journal of Medicine. 370: 433-43. PMID 24350901 DOI: 10.1056/Nejmoa1114576 |
0.353 |
|
| 2014 |
Farina A, Cirone M, York M, Lenna S, Padilla C, McLaughlin S, Faggioni A, Lafyatis R, Trojanowska M, Farina GA. Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma. The Journal of Investigative Dermatology. 134: 954-64. PMID 24129067 DOI: 10.1038/Jid.2013.423 |
0.408 |
|
| 2013 |
Asano Y, Trojanowska M. Fli1 represses transcription of the human α2(I) collagen gene by recruitment of the HDAC1/p300 complex. Plos One. 8. PMID 24058639 DOI: 10.1371/Journal.Pone.0074930 |
0.401 |
|
| 2013 |
Leach HG, Chrobak I, Han R, Trojanowska M. Endothelial cells recruit macrophages and contribute to a fibrotic milieu in bleomycin lung injury. American Journal of Respiratory Cell and Molecular Biology. 49: 1093-101. PMID 23885794 DOI: 10.1165/Rcmb.2013-0152Oc |
0.396 |
|
| 2013 |
Chan ES, Liu H, Fernandez P, Luna A, Perez-Aso M, Bujor AM, Trojanowska M, Cronstein BN. Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism. Arthritis Research & Therapy. 15: R58. PMID 23663495 DOI: 10.1186/Ar4229 |
0.337 |
|
| 2013 |
Ghatnekar A, Chrobak I, Reese C, Stawski L, Seta F, Wirrig E, Paez-Cortez J, Markiewicz M, Asano Y, Harley R, Silver R, Feghali-Bostwick C, Trojanowska M. Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension. The American Journal of Pathology. 182: 2391-406. PMID 23583651 DOI: 10.1016/J.Ajpath.2013.02.039 |
0.758 |
|
| 2013 |
Lenna S, Chrobak I, Farina GA, Rodriguez-Pascual F, Lamas S, Lafyatis R, Scorza R, Trojanowska M. HLA-B35 and dsRNA Induce Endothelin-1 via Activation of ATF4 in Human Microvascular Endothelial Cells Plos One. 8. PMID 23441162 DOI: 10.1371/Journal.Pone.0056123 |
0.345 |
|
| 2013 |
Lenna S, Farina AG, Martyanov V, Christmann RB, Wood TA, Farber HW, Scorza R, Whitfield ML, Lafyatis R, Trojanowska M. Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension. Arthritis and Rheumatism. 65: 1357-66. PMID 23400395 DOI: 10.1002/Art.37891 |
0.328 |
|
| 2013 |
Chrobak I, Lenna S, Stawski L, Trojanowska M. Interferon-γ Promotes Vascular Remodeling in Human Microvascular Endothelial Cells by Upregulating Endothelin (ET)-1 and Transforming Growth Factor (TGF) β2 Journal of Cellular Physiology. 228: 1774-1783. PMID 23359533 DOI: 10.1002/Jcp.24337 |
0.315 |
|
| 2013 |
Markiewicz M, Znoyko S, Stawski L, Ghatnekar A, Gilkeson G, Trojanowska M. A role for estrogen receptor-α and estrogen receptor-β in collagen biosynthesis in mouse skin. The Journal of Investigative Dermatology. 133: 120-7. PMID 22895361 DOI: 10.1038/Jid.2012.264 |
0.779 |
|
| 2012 |
Bujor AM, Haines P, Padilla C, Christmann RB, Junie M, Sampaio-Barros PD, Lafyatis R, Trojanowska M. Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1 International Journal of Molecular Medicine. 30: 1473-1480. PMID 23041765 DOI: 10.3892/Ijmm.2012.1150 |
0.458 |
|
| 2012 |
Stawski L, Han R, Bujor AM, Trojanowska M. Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis. Arthritis Research & Therapy. 14: R194. PMID 22913887 DOI: 10.1186/Ar4028 |
0.398 |
|
| 2012 |
Nakerakanti S, Trojanowska M. The Role of TGF-β Receptors in Fibrosis. The Open Rheumatology Journal. 6: 156-162. PMID 22802914 DOI: 10.2174/1874312901206010156 |
0.414 |
|
| 2012 |
Trojanowska M. Mediators of fibrosis. The Open Rheumatology Journal. 6: 70-71. PMID 22802903 DOI: 10.2174/1874312901206010070 |
0.43 |
|
| 2012 |
Samuel GH, Lenna S, Bujor AM, Lafyatis R, Trojanowska M. Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis Journal of Dermatological Science. 67: 166-172. PMID 22771321 DOI: 10.1016/J.Jdermsci.2012.06.001 |
0.763 |
|
| 2012 |
Maring JA, Trojanowska M, Dijke Pt. Role of Endoglin in Fibrosis and Scleroderma International Review of Cell and Molecular Biology. 297: 295-308. PMID 22608563 DOI: 10.1016/B978-0-12-394308-8.00008-X |
0.43 |
|
| 2012 |
Haines P, Hant FN, Lafyatis R, Trojanowska M, Bujor AM. Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation Journal of Cellular and Molecular Medicine. 16: 2238-2246. PMID 22277251 DOI: 10.1111/J.1582-4934.2012.01537.X |
0.499 |
|
| 2011 |
Haines P, Samuel GH, Cohen H, Trojanowska M, Bujor AM. Caveolin-1 is a negative regulator of MMP-1 gene expression in human dermal fibroblasts via inhibition of Erk1/2/Ets1 signaling pathway. Journal of Dermatological Science. 64: 210-6. PMID 21925842 DOI: 10.1016/J.Jdermsci.2011.08.005 |
0.784 |
|
| 2011 |
Nakerakanti SS, Bujor AM, Trojanowska M. CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling network. Plos One. 6. PMID 21760921 DOI: 10.1371/Journal.Pone.0021911 |
0.464 |
|
| 2011 |
Hattori T, Stawski L, Nakerakanti SS, Trojanowska M. Fli1 Is a Negative Regulator of Estrogen Receptor α in Dermal Fibroblasts Journal of Investigative Dermatology. 131: 1469-1476. PMID 21451544 DOI: 10.1038/Jid.2011.63 |
0.496 |
|
| 2011 |
Morris E, Chrobak I, Bujor A, Hant F, Mummery C, Ten Dijke P, Trojanowska M. Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts. Journal of Cellular Physiology. 226: 3340-8. PMID 21344387 DOI: 10.1002/Jcp.22690 |
0.512 |
|
| 2011 |
Bujor AM, Asano Y, Haines P, Lafyatis R, Trojanowska M. The c-Abl tyrosine kinase controls protein kinase Cδ-induced Fli-1 phosphorylation in human dermal fibroblasts. Arthritis & Rheumatism. 63: 1729-1737. PMID 21321929 DOI: 10.1002/Art.30284 |
0.517 |
|
| 2011 |
Markiewicz M, Nakerakanti SS, Kapanadze B, Ghatnekar A, Trojanowska M. Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells. Microcirculation (New York, N.Y. : 1994). 18: 1-11. PMID 21166920 DOI: 10.1111/J.1549-8719.2010.00058.X |
0.762 |
|
| 2010 |
Samuel GH, Bujor AM, Nakerakanti SS, Hant FN, Trojanowska M. Autocrine transforming growth factor β signaling regulates extracellular signal-regulated kinase 1/2 phosphorylation via modulation of protein phosphatase 2A expression in scleroderma fibroblasts. Fibrogenesis & Tissue Repair. 3: 25. PMID 21134273 DOI: 10.1186/1755-1536-3-25 |
0.786 |
|
| 2010 |
Asano Y, Bujor AM, Trojanowska M. The impact of Fli1 deficiency on the pathogenesis of systemic sclerosis Journal of Dermatological Science. 59: 153-162. PMID 20663647 DOI: 10.1016/J.Jdermsci.2010.06.008 |
0.396 |
|
| 2010 |
Trojanowska M. Cellular and molecular aspects of vascular dysfunction in systemic sclerosis Nature Reviews Rheumatology. 6: 453-460. PMID 20585340 DOI: 10.1038/Nrrheum.2010.102 |
0.339 |
|
| 2010 |
Lenna S, Townsend DM, Tan FK, Kapanadze B, Markiewicz M, Trojanowska M, Scorza R. HLA-B35 Upregulates Endothelin-1 and Downregulates Endothelial Nitric Oxide Synthase via Endoplasmic Reticulum Stress Response in Endothelial Cells Journal of Immunology. 184: 4654-4661. PMID 20335527 DOI: 10.4049/Jimmunol.0903188 |
0.324 |
|
| 2010 |
Bu S, Asano Y, Bujor A, Highland K, Hant F, Trojanowska M. Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels. Arthritis & Rheumatism. 62: 2117-2126. PMID 20309867 DOI: 10.1002/Art.27463 |
0.414 |
|
| 2010 |
Asano Y, Stawski L, Hant F, Highland K, Silver R, Szalai G, Watson DK, Trojanowska M. Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy. The American Journal of Pathology. 176: 1983-98. PMID 20228226 DOI: 10.2353/Ajpath.2010.090593 |
0.414 |
|
| 2010 |
Bujor AM, Nakerakanti S, Morris E, Hant FN, Trojanowska M. Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts. Experimental Dermatology. 19: 347-354. PMID 20201953 DOI: 10.1111/J.1600-0625.2010.01065.X |
0.428 |
|
| 2009 |
Trojanowska M. Noncanonical transforming growth factor β signaling in scleroderma fibrosis Current Opinion in Rheumatology. 21: 623-629. PMID 19713852 DOI: 10.1097/Bor.0B013E32833038Ce |
0.4 |
|
| 2009 |
Kapanadze B, Morris E, Smith E, Trojanowska M. Establishment and characterization of scleroderma fibroblast clonal cell lines by introduction of the hTERT gene Journal of Cellular and Molecular Medicine. 14: 1156-1165. PMID 19432820 DOI: 10.1111/J.1582-4934.2009.00773.X |
0.444 |
|
| 2009 |
Asano Y, Trojanowska M. Phosphorylation of Fli1 at Threonine 312 by Protein Kinase C δ Promotes Its Interaction with p300/CREB-Binding Protein-Associated Factor and Subsequent Acetylation in Response to Transforming Growth Factor β Molecular and Cellular Biology. 29: 1882-1894. PMID 19158279 DOI: 10.1128/Mcb.01320-08 |
0.442 |
|
| 2009 |
Asano Y, Markiewicz M, Kubo M, Szalai G, Watson DK, Trojanowska M. Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin Molecular and Cellular Biology. 29: 425-434. PMID 19001092 DOI: 10.1128/Mcb.01278-08 |
0.423 |
|
| 2008 |
Trojanowska M. Role of PDGF in fibrotic diseases and systemic sclerosis Rheumatology. 47. PMID 18784131 DOI: 10.1093/Rheumatology/Ken265 |
0.435 |
|
| 2008 |
Pannu J, Asano Y, Nakerakanti S, Smith E, Jablonska S, Blaszczyk M, ten Dijke P, Trojanowska M. Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate. Arthritis and Rheumatism. 58: 2528-37. PMID 18668566 DOI: 10.1002/Art.23698 |
0.347 |
|
| 2008 |
Bu S, Kapanadze B, Hsu T, Trojanowska M. Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway. The Journal of Biological Chemistry. 283: 19593-602. PMID 18482992 DOI: 10.1074/Jbc.M802417200 |
0.43 |
|
| 2008 |
Bujor AM, Pannu J, Bu S, Smith EA, Muise-Helmericks RC, Trojanowska M. Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts. The Journal of Investigative Dermatology. 128: 1906-14. PMID 18323784 DOI: 10.1038/Jid.2008.39 |
0.476 |
|
| 2008 |
Chintalapudi MR, Markiewicz M, Kose N, Dammai V, Champion KJ, Hoda RS, Trojanowska M, Hsu T. Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells. Carcinogenesis. 29: 696-703. PMID 18212329 DOI: 10.1093/Carcin/Bgn019 |
0.401 |
|
| 2008 |
Ghatnekar A, Trojanowska M. GATA-6 is a novel transcriptional repressor of the human Tenascin-C gene expression in fibroblasts. Biochimica Et Biophysica Acta. 1779: 145-51. PMID 18177748 DOI: 10.1016/J.Bbagrm.2007.11.012 |
0.771 |
|
| 2007 |
Asano Y, Czuwara J, Trojanowska M. Transforming Growth Factor-β Regulates DNA Binding Activity of Transcription Factor Fli1 by p300/CREB-binding Protein-associated Factor-dependent Acetylation Journal of Biological Chemistry. 282: 34672-34683. PMID 17884818 DOI: 10.1074/Jbc.M703907200 |
0.469 |
|
| 2007 |
Mayes MD, Trojanowska M. Genetic factors in systemic sclerosis Arthritis Research & Therapy. 9: 1-7. PMID 17767743 DOI: 10.1186/Ar2189 |
0.37 |
|
| 2007 |
Markiewicz M, Asano Y, Znoyko S, Gong Y, Watson DK, Trojanowska M. Distinct effects of gonadectomy in male and female mice on collagen fibrillogenesis in the skin Journal of Dermatological Science. 47: 217-226. PMID 17601707 DOI: 10.1016/J.Jdermsci.2007.05.008 |
0.442 |
|
| 2007 |
Pannu J, Nakerakanti S, Smith E, ten Dijke P, Trojanowska M. Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways. The Journal of Biological Chemistry. 282: 10405-13. PMID 17317656 DOI: 10.1074/Jbc.M611742200 |
0.481 |
|
| 2006 |
Pannu J, Gardner H, Shearstone JR, Smith E, Trojanowska M. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma. Arthritis and Rheumatism. 54: 3011-21. PMID 16947635 DOI: 10.1002/Art.22063 |
0.485 |
|
| 2006 |
Nakerakanti SS, Kapanadze B, Yamasaki M, Markiewicz M, Trojanowska M. Fli1 and Ets1 Have Distinct Roles in Connective Tissue Growth Factor/CCN2 Gene Regulation and Induction of the Profibrotic Gene Program Journal of Biological Chemistry. 281: 25259-25269. PMID 16829517 DOI: 10.1074/Jbc.M600466200 |
0.486 |
|
| 2006 |
Gardner H, Shearstone JR, Bandaru R, Crowell T, Lynes M, Trojanowska M, Pannu J, Smith E, Jablonska S, Blaszczyk M, Tan FK, Mayes MD. Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts. Arthritis and Rheumatism. 54: 1961-73. PMID 16736506 DOI: 10.1002/Art.21894 |
0.364 |
|
| 2006 |
Jinnin M, Ihn H, Asano Y, Yamane K, Trojanowska M, Tamaki K. Upregulation of tenascin-C expression by IL-13 in human dermal fibroblasts via the phosphoinositide 3-kinase/Akt and the protein kinase C signaling pathways. Journal of Investigative Dermatology. 126: 551-560. PMID 16374482 DOI: 10.1038/Sj.Jid.5700090 |
0.325 |
|
| 2006 |
Znoyko I, Trojanowska M, Reuben A. Collagen binding alpha2beta1 and alpha1beta1 integrins play contrasting roles in regulation of Ets-1 expression in human liver myofibroblasts. Molecular and Cellular Biochemistry. 282: 89-99. PMID 16317516 DOI: 10.1007/S11010-006-1400-0 |
0.435 |
|
| 2006 |
Sohn M, Tan Y, Wang B, Klein RL, Trojanowska M, Jaffa AA. Mechanisms of low-density lipoprotein-induced expression of connective tissue growth factor in human aortic endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 290: H1624-34. PMID 16272194 DOI: 10.1152/Ajpheart.01233.2004 |
0.35 |
|
| 2006 |
Jinnin M, Ihn H, Asano Y, Yamane K, Trojanowska M, Tamaki K. Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors. Journal of Cellular Physiology. 206: 718-727. PMID 16245312 DOI: 10.1002/Jcp.20527 |
0.411 |
|
| 2005 |
Bu S, Yamanaka M, Pei H, Bielawska A, Bielawski J, Hannun YA, Obeid L, Trojanowska M. Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 184-6. PMID 16278291 DOI: 10.1096/Fj.05-4646Fje |
0.417 |
|
| 2005 |
Znoyko I, Sohara N, Spicer SS, Trojanowska M, Reuben A. Expression of oncostatin M and its receptors in normal and cirrhotic human liver. Journal of Hepatology. 43: 893-900. PMID 16169119 DOI: 10.1016/J.Jhep.2005.04.020 |
0.321 |
|
| 2005 |
Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta. Arthritis and Rheumatism. 52: 1248-58. PMID 15818659 DOI: 10.1002/Art.20996 |
0.408 |
|
| 2005 |
Tourkina E, Gooz P, Pannu J, Bonner M, Scholz D, Hacker S, Silver RM, Trojanowska M, Hoffman S. Opposing effects of protein kinase Calpha and protein kinase Cepsilon on collagen expression by human lung fibroblasts are mediated via MEK/ERK and caveolin-1 signaling. The Journal of Biological Chemistry. 280: 13879-87. PMID 15691837 DOI: 10.1074/Jbc.M412551200 |
0.422 |
|
| 2004 |
Pannu J, Trojanowska M. Recent advances in fibroblast signaling and biology in scleroderma. Current Opinion in Rheumatology. 16: 739-45. PMID 15577613 DOI: 10.1097/01.Bor.0000137894.63091.1A |
0.388 |
|
| 2004 |
Sato M, Shegogue D, Hatamochi A, Yamazaki S, Trojanowska M. Lysophosphatidic acid inhibits TGF-β-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts Matrix Biology. 23: 353-361. PMID 15533756 DOI: 10.1016/J.Matbio.2004.07.005 |
0.806 |
|
| 2004 |
Yamanaka M, Shegogue D, Pei H, Bu S, Bielawska A, Bielawski J, Pettus B, Hannun YA, Obeid L, Trojanowska M. Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation. The Journal of Biological Chemistry. 279: 53994-4001. PMID 15485866 DOI: 10.1074/Jbc.M410144200 |
0.793 |
|
| 2004 |
Pannu J, Gore-Hyer E, Yamanaka M, Smith EA, Rubinchik S, Dong JY, Jablonska S, Blaszczyk M, Trojanowska M. An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma. Arthritis and Rheumatism. 50: 1566-77. PMID 15146427 DOI: 10.1002/Art.20225 |
0.428 |
|
| 2004 |
Shegogue DA, Trojanowska M. Mammalian Target of Rapamycin Positively Regulates Collagen Type I Production via a Phosphatidylinositol 3-Kinase-independent Pathway Journal of Biological Chemistry. 279: 23166-23175. PMID 15047702 DOI: 10.1074/Jbc.M401238200 |
0.787 |
|
| 2004 |
Jinnin M, Ihn H, Asano Y, Yamane K, Trojanowska M, Tamaki K. Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1. Oncogene. 23: 1656-1667. PMID 15001984 DOI: 10.1038/Sj.Onc.1207064 |
0.43 |
|
| 2003 |
Kubo M, Czuwara-Ladykowska J, Moussa O, Markiewicz M, Smith E, Silver RM, Jablonska S, Blaszczyk M, Watson DK, Trojanowska M. Persistent Down-Regulation of Fli1, a Suppressor of Collagen Transcription, in Fibrotic Scleroderma Skin American Journal of Pathology. 163: 571-581. PMID 12875977 DOI: 10.1016/S0002-9440(10)63685-1 |
0.425 |
|
| 2003 |
Atamas SP, Luzina IG, Choi J, Tsymbalyuk N, Carbonetti NH, Singh IS, Trojanowska M, Jimenez SA, White B. Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 29: 743-9. PMID 12805086 DOI: 10.1165/Rcmb.2003-0078Oc |
0.4 |
|
| 2003 |
Gore-Hyer E, Pannu J, Smith EA, Grotendorst G, Trojanowska M. Selective stimulation of collagen synthesis in the presence of costimulatory insulin signaling by connective tissue growth factor in scleroderma fibroblasts. Arthritis and Rheumatism. 48: 798-806. PMID 12632435 DOI: 10.1002/Art.10953 |
0.396 |
|
| 2003 |
Sato M, Markiewicz M, Yamanaka M, Bielawska A, Mao C, Obeid LM, Hannun YA, Trojanowska M. Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators. The Journal of Biological Chemistry. 278: 9276-82. PMID 12515830 DOI: 10.1074/Jbc.M211529200 |
0.448 |
|
| 2002 |
Gore-Hyer E, Shegogue D, Markiewicz M, Lo S, Hazen-Martin D, Greene EL, Grotendorst G, Trojanowska M. TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells. American Journal of Physiology. Renal Physiology. 283: F707-16. PMID 12217862 DOI: 10.1152/Ajprenal.00007.2002 |
0.786 |
|
| 2002 |
Czuwara-Ladykowska J, Sementchenko VI, Watson DK, Trojanowska M. Ets1 is an effector of the transforming growth factor β (TGF-β) signaling pathway and an antagonist of the profibrotic effects of TGF-β Journal of Biological Chemistry. 277: 20399-20408. PMID 11919190 DOI: 10.1074/Jbc.M200206200 |
0.437 |
|
| 2002 |
Sato M, Shegogue D, Gore EA, Smith EA, McDermott PJ, Trojanowska M. Role of p38 MAPK in Transforming Growth Factor β Stimulation of Collagen Production by Scleroderma and Healthy Dermal Fibroblasts Journal of Investigative Dermatology. 118: 704-711. PMID 11918720 DOI: 10.1046/J.1523-1747.2002.01719.X |
0.798 |
|
| 2002 |
Trojanowska M. Molecular aspects of scleroderma. Frontiers in Bioscience : a Journal and Virtual Library. 7: d608-18. PMID 11861221 DOI: 10.2741/A798 |
0.363 |
|
| 2002 |
Sohara N, Trojanowska M, Reuben A. Oncostatin M stimulates tissue inhibitor of metalloproteinase-1 via a MEK-sensitive mechanism in human myofibroblasts Journal of Hepatology. 36: 191-199. PMID 11830330 DOI: 10.1016/S0168-8278(01)00265-3 |
0.383 |
|
| 2002 |
Trojanowska M. Molecular aspects of scleroderma. Frontiers in Bioscience. 7. DOI: 10.2741/Trojan |
0.467 |
|
| 2002 |
Sohara N, Znoyko I, Levy MT, Trojanowska M, Reuben A. Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate Journal of Hepatology. 37: 214-221. DOI: 10.1016/S0168-8278(02)00103-4 |
0.392 |
|
| 2001 |
Czuwara-Ladykowska J, Gore EA, Shegogue DA, Smith EA, Trojanowska M. Differential regulation of transforming growth factor-beta receptors type I and II by platelet-derived growth factor in human dermal fibroblasts. The British Journal of Dermatology. 145: 569-75. PMID 11703282 DOI: 10.1046/J.1365-2133.2001.04443.X |
0.779 |
|
| 2001 |
Czuwara-Ladykowska J, Makiela B, Smith EA, Trojanowska M, Rudnicka L. The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis Arthritis Research & Therapy. 3: 311-318. PMID 11549373 DOI: 10.1186/Ar321 |
0.407 |
|
| 2001 |
Ihn H, Ihn Y, Trojanowska M. Spl Phosphorylation Induced by Serum Stimulates the Human α2(I) Collagen Gene Expression Journal of Investigative Dermatology. 117: 301-308. PMID 11511308 DOI: 10.1046/J.0022-202X.2001.01371.X |
0.343 |
|
| 2001 |
Czuwara-Ladykowska J, Shirasaki F, Jackers P, Watson DK, Trojanowska M. Fli-1 Inhibits Collagen Type I Production in Dermal Fibroblasts via an Sp1-dependent Pathway Journal of Biological Chemistry. 276: 20839-20848. PMID 11278621 DOI: 10.1074/Jbc.M010133200 |
0.401 |
|
| 2000 |
Trojanowska M. Ets factors and regulation of the extracellular matrix Oncogene. 19: 6464-6471. PMID 11175362 DOI: 10.1038/Sj.Onc.1204043 |
0.379 |
|
| 2000 |
Douillet CD, Velarde V, Christopher JT, Mayfield RK, Trojanowska ME, Jaffa AA. Mechanisms by which bradykinin promotes fibrosis in vascular smooth muscle cells: role of TGF-beta and MAPK. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2829-37. PMID 11087238 DOI: 10.1152/Ajpheart.2000.279.6.H2829 |
0.408 |
|
| 2000 |
Chen SJ, Yuan W, Lo S, Trojanowska M, Varga J. Interaction of Smad3 with a proximal smad-binding element of the human α2(I) procollagen gene promoter required for transcriptional activation by TGF-β Journal of Cellular Physiology. 183: 381-392. PMID 10797313 DOI: 10.1002/(Sici)1097-4652(200006)183:3<381::Aid-Jcp11>3.0.Co;2-O |
0.444 |
|
| 2000 |
Levy MT, Trojanowska M, Reuben A. Oncostatin M: A cytokine upregulated in human cirrhosis, increases collagen production by human hepatic stellate cells Journal of Hepatology. 32: 218-226. PMID 10707861 DOI: 10.1016/S0168-8278(00)80066-5 |
0.377 |
|
| 2000 |
Sohara N, Trojanowska M, Reuben A. Oncostatin M (OSM) stimulates tissue inhibitor of metalloproteinase-1 (TIMP1) via a MEK-sensitive mechanism in human hepatic stellate cells (hHSCs) Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86101-6 |
0.303 |
|
| 1999 |
Shirasaki F, Makhluf HA, LeRoy C, Watson DK, Trojanowska M. Ets transcription factors cooperate with Sp1 to activate the human Tenascin-C promoter Oncogene. 18: 7755-7764. PMID 10618716 DOI: 10.1038/Sj.Onc.1203360 |
0.378 |
|
| 1999 |
Chen SJ, Yuan W, Mori Y, Levenson A, Trojanowska M, Varga J. Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3 Journal of Investigative Dermatology. 112: 49-57. PMID 9886263 DOI: 10.1046/J.1523-1747.1999.00477.X |
0.453 |
|
| 1998 |
Kawakami T, Ihn H, Xu W, Smith E, LeRoy C, Trojanowska M. Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype Journal of Investigative Dermatology. 110: 47-51. PMID 9424086 DOI: 10.1046/J.1523-1747.1998.00073.X |
0.443 |
|
| 1997 |
Ihn H, LeRoy EC, Trojanowska M. Oncostatin M Stimulates Transcription of the Human α2(I) Collagen Gene via the Sp1/Sp3-binding Site Journal of Biological Chemistry. 272: 24666-24672. PMID 9305936 DOI: 10.1074/Jbc.272.39.24666 |
0.365 |
|
| 1997 |
Ihn H, Trojanowska M. Sp3 is a transcriptional activator of the human α2(I) collagen gene Nucleic Acids Research. 25: 3712-3717. PMID 9278495 DOI: 10.1093/Nar/25.18.3712 |
0.319 |
|
| 1996 |
Makhluf HA, Stepniakowska J, Hoffman S, Smith E, LeRoy EC, Trojanowska M. IL-4 upregulates tenascin synthesis in scleroderma and healthy skin fibroblasts. Journal of Investigative Dermatology. 107: 856-859. PMID 8941674 DOI: 10.1111/1523-1747.Ep12331160 |
0.368 |
|
| 1995 |
Tamaki T, Tamaki K, LeRoy EC, Trojanowska M. 113 Characterization of a gc-rich region containing Sp1 binding site(S) as a constitutive responsive element of the α2(I) collagen gene in human fibroblasts Journal of Dermatological Science. 10: 81. DOI: 10.1016/0923-1811(95)93826-M |
0.304 |
|
| 1995 |
Ohnishi K, Tamaki T, LeRoy EC, Trojanowska M. 103 Human collagen α2(1) promoter is constitutively regulated by CAAT binding factor CBF Journal of Dermatological Science. 10: 80. DOI: 10.1016/0923-1811(95)93817-K |
0.349 |
|
| 1994 |
Trojanowska M, Tamaki T, Ichiki Y, LeRoy EC. Transcriptional regulation of human collagen α2(I) promoter in human fibroblasts Matrix Biology. 14: 381. DOI: 10.1016/0945-053X(94)90095-7 |
0.348 |
|
| 1994 |
Ichiki Y, Trojanowska M, Leroy EC. Basic FGF inhibits collagen α2(I) gene expression in scleroderma and normal fibroblasts Journal of Dermatological Science. 8: 74. DOI: 10.1016/0923-1811(94)90437-5 |
0.376 |
|
| 1993 |
Feldman SR, Trojanowska M, Smith EA, Leroy EC. Differential Responses of Human Papillary and Reticular Fibroblasts to Growth Factors The American Journal of the Medical Sciences. 305: 203-207. PMID 8475944 DOI: 10.1097/00000441-199304000-00002 |
0.434 |
|
| 1992 |
Kikuchi K, Hartl CW, Smith EA, LeRoy EC, Trojanowska M. Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: Insensitivity to TGFβ1 stimulation Biochemical and Biophysical Research Communications. 187: 45-50. PMID 1520334 DOI: 10.1016/S0006-291X(05)81456-1 |
0.44 |
|
| 1992 |
Kikuchi K, Yamakage A, Smith EA, LeRoy EC, Trojanowska M. Differential Modulation of bFGF Receptors by TGF-β in Adult Skin, Scleroderma Skin, and Newborn Foreskin Fibroblasts Journal of Investigative Dermatology. 99: 201-205. PMID 1321201 DOI: 10.1111/1523-1747.Ep12650432 |
0.416 |
|
| 1992 |
Yamakage A, Kikuchi K, Smith EA, LeRoy EC, Trojanowska M. Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts. Journal of Experimental Medicine. 175: 1227-1234. PMID 1314885 DOI: 10.1084/Jem.175.5.1227 |
0.392 |
|
| 1992 |
Kikuchi K, LeRoy EC, Trojanowska M. Differential modulation of bFGF receptors by TGF-beta in adult skin, scleroderma skin, and newborn foreskin fibroblasts. Journal of Dermatology. 19: 660-663. PMID 1293150 DOI: 10.1111/J.1346-8138.1992.Tb03754.X |
0.336 |
|
| 1990 |
Ishikawa O, Yamakage A, LeRoy EC, Trojanowska M. Persistent effect of TGF-β1 on extracellular matrix gene expression in human dermal fibroblasts Biochemical and Biophysical Research Communications. 169: 232-238. PMID 2350346 DOI: 10.1016/0006-291X(90)91458-5 |
0.43 |
|
| 1990 |
Ishikawa O, LeRoy EC, Trojanowska M. Mitogenic effect of transforming growth factor β1 on human fibroblasts involves the induction of platelet-derived growth factor α receptors Journal of Cellular Physiology. 145: 181-186. PMID 2170429 DOI: 10.1002/Jcp.1041450124 |
0.425 |
|
| 1987 |
Takehara K, Grotendorst GR, Trojanowska M, Leroy EC. Abscorbate Effects on Type I Procollagen Synthesis by Human Adult Skin Fibroblasts: Different Migration Positions of Type I Procollagen Chains on SDS Polyacrylamide Gel after Incubation with Ascorbate Collagen and Related Research. 6: 455-466. PMID 3581751 DOI: 10.1016/S0174-173X(87)80045-6 |
0.339 |
|
| 1987 |
Miller ES, Karam J, Dawson M, Trojanowska M, Gauss P, Gold L. Translational repression: biological activity of plasmid-encoded bacteriophage T4 RegA protein. Journal of Molecular Biology. 194: 397-410. PMID 3498046 DOI: 10.1016/0022-2836(87)90670-X |
0.311 |
|
| Show low-probability matches. |