Simon Rousseau, Ph.D. - Publications

Affiliations: 
2000 Universite Laval (Canada) 
Area:
Cell Biology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Renteria AE, Endam Mfuna L, Adam D, Filali-Mouhim A, Maniakas A, Rousseau S, Brochiero E, Gallo S, Desrosiers M. Azithromycin Downregulates Gene Expression of IL-1β and Pathways Involving TMPRSS2 and TMPRSS11D Required by SARS-CoV-2. American Journal of Respiratory Cell and Molecular Biology. PMID 32857620 DOI: 10.1165/Rcmb.2020-0285Le  0.349
2020 Barnes BJ, Adrover JM, Baxter-Stoltzfus A, Borczuk A, Cools-Lartigue J, Crawford JM, Daßler-Plenker J, Guerci P, Huynh C, Knight JS, Loda M, Looney MR, McAllister F, Rayes R, Renaud S, ... Rousseau S, et al. Targeting potential drivers of COVID-19: Neutrophil extracellular traps. The Journal of Experimental Medicine. 217. PMID 32302401 DOI: 10.1084/Jem.20200652  0.339
2020 Jiang HY, Najmeh S, Martel G, MacFadden-Murphy E, Farias R, Savage P, Leone A, Roussel L, Cools-Lartigue J, Gowing S, Berube J, Giannias B, Bourdeau F, Chan CHF, Spicer JD, ... ... Rousseau S, et al. Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis. Protein & Cell. PMID 31956962 DOI: 10.1007/S13238-019-00687-5  0.4
2019 Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Goodwin-Wilson M, Jiang HY, Bourdeau F, Beauchamp A, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE. Gram-Negative Pneumonia Augments Non-Small Cell Lung Cancer Metastasis Through Host Toll-like Receptor 4 Activation. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 31382038 DOI: 10.1016/J.Jtho.2019.07.023  0.404
2019 Rayes RF, Mouhanna JG, Nicolau I, Bourdeau F, Giannias B, Rousseau S, Quail D, Walsh L, Sangwan V, Bertos N, Cools-Lartigue J, Ferri LE, Spicer JD. Primary tumors induce neutrophil extracellular traps with targetable metastasis promoting effects. Jci Insight. 5. PMID 31343990 DOI: 10.1172/Jci.Insight.128008  0.347
2019 Allakhverdi Z, Gaudet M, Plesa M, Mogas A, Rousseau S, Martin JG, Hamid Q. Effect of Azithromycin on EGFR Expression in Human Bronchial Epithelial Cells The Journal of Allergy and Clinical Immunology. 143. DOI: 10.1016/J.Jaci.2018.12.573  0.33
2017 Ruffin M, Roussel L, Maillé É, Rousseau S, Brochiero E. Vx-809/Vx-770 treatment reduces inflammatory response to Pseudomonas aeruginosa in primary differentiated cystic fibrosis bronchial epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29351441 DOI: 10.1152/Ajplung.00198.2017  0.412
2017 Mizutani M, Bérubé J, Ahlgren HG, Bernier J, Matouk E, Nguyen D, Rousseau S. Corticosteroid-resistant inflammatory signalling in Pseudomonas-infected bronchial cells. Erj Open Research. 3. PMID 28656134 DOI: 10.1183/23120541.00144-2016  0.401
2017 Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Jiang HY, Bourdeau F, Beauchamp A, Mancini U, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE. Gram-Positive Pneumonia Augments Non-Small Cell Lung Cancer Metastasis Via Host Toll-like Receptor 2 Activation. International Journal of Cancer. PMID 28401532 DOI: 10.1002/Ijc.30734  0.385
2017 Najmeh S, Cools-Lartigue J, Rayes RF, Gowing S, Vourtzoumis P, Bourdeau F, Giannias B, Berube J, Rousseau S, Ferri LE, Spicer JD. Neutrophil Extracellular Traps sequester circulating tumor cells via β1-integrin mediated interactions. International Journal of Cancer. PMID 28177522 DOI: 10.1002/Ijc.30635  0.34
2017 Rammal A, Tewfik M, Rousseau S. Differences in RANTES and IL-6 levels among chronic rhinosinusitis patients with predominant gram-negative and gram-positive infection. Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-Rhino-Laryngologie Et De Chirurgie Cervico-Faciale. 46: 7. PMID 28095898 DOI: 10.1186/S40463-016-0183-X  0.308
2017 Roussel L, Rousseau S. Exposure of airway epithelial cells to Pseudomonas aeruginosa biofilm-derived quorum sensing molecules decrease the activity of the anti-oxidant response element bound by NRF2. Biochemical and Biophysical Research Communications. PMID 28062182 DOI: 10.1016/J.Bbrc.2017.01.009  0.433
2016 Roussel L, LaFayette S, Nguyen D, Baglole CJ, Rousseau S. Differential Contribution of the Aryl-Hydrocarbon Receptor and Toll-Like Receptor Pathways to IL-8 Expression in Normal and Cystic Fibrosis Airway Epithelial Cells Exposed to Pseudomonas aeruginosa. Frontiers in Cell and Developmental Biology. 4: 148. PMID 28066767 DOI: 10.3389/Fcell.2016.00148  0.423
2016 MacFadden-Murphy E, Roussel L, Martel G, Bérubé J, Rousseau S. Decreasing SMPD1 activity in BEAS-2B bronchial airway epithelial cells results in increased NRF2 activity, cytokine synthesis and neutrophil recruitment. Biochemical and Biophysical Research Communications. PMID 27865842 DOI: 10.1016/J.Bbrc.2016.11.087  0.421
2016 Schnúr A, Hegyi P, Rousseau S, Lukacs GL, Veit G. Epithelial Anion Transport as Modulator of Chemokine Signaling. Mediators of Inflammation. 2016: 7596531. PMID 27382190 DOI: 10.1155/2016/7596531  0.365
2016 Rousseau S, Martel G. Gain-of-Function Mutations in the Toll-Like Receptor Pathway: TPL2-Mediated ERK1/ERK2 MAPK Activation, a Path to Tumorigenesis in Lymphoid Neoplasms? Frontiers in Cell and Developmental Biology. 4: 50. PMID 27303665 DOI: 10.3389/Fcell.2016.00050  0.415
2016 Ruffin M, Bilodeau C, Maillé É, LaFayette SL, McKay GA, Trinh NT, Beaudoin T, Desrosiers MY, Rousseau S, Nguyen D, Brochiero E. Quorum-sensing inhibition abrogates the deleterious impact of Pseudomonas aeruginosa on airway epithelial repair. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27178322 DOI: 10.1096/Fj.201500166R  0.385
2016 Vourtzoumis P, Seth R, Rayes R, Najmeh S, Cools-Lartigue J, Giannias B, Beauchemin N, Rousseau S, Blumberg R, Spicer JD, Ferri LE. Abstract LB-078: The role of CEACAM1 in neutrophil extracellular Trap mediated cancer metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-078  0.371
2015 Farias R, Rousseau S. The TAK1→IKKβ→TPL2→MKK1/MKK2 Signaling Cascade Regulates IL-33 Expression in Cystic Fibrosis Airway Epithelial Cells Following Infection by Pseudomonas aeruginosa. Frontiers in Cell and Developmental Biology. 3: 87. PMID 26793709 DOI: 10.3389/Fcell.2015.00087  0.422
2015 Dauletbaev N, Das M, Cammisano M, Chen H, Singh S, Kooi C, Leigh R, Beaudoin T, Rousseau S, Lands LC. Rhinovirus Load Is High despite Preserved Interferon-β Response in Cystic Fibrosis Bronchial Epithelial Cells. Plos One. 10: e0143129. PMID 26599098 DOI: 10.1371/Journal.Pone.0143129  0.375
2015 LaFayette SL, Houle D, Beaudoin T, Wojewodka G, Radzioch D, Hoffman LR, Burns JL, Dandekar AA, Smalley NE, Chandler JR, Zlosnik JE, Speert DP, Bernier J, Matouk E, Brochiero E, ... Rousseau S, et al. Cystic fibrosis-adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses. Science Advances. 1. PMID 26457326 DOI: 10.1126/Sciadv.1500199  0.388
2015 Sarill M, Zago M, Sheridan JA, Nair P, Matthews J, Gomez A, Roussel L, Rousseau S, Hamid Q, Eidelman DH, Baglole CJ. The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1. Free Radical Biology & Medicine. 89: 342-357. PMID 26408075 DOI: 10.1016/J.Freeradbiomed.2015.08.007  0.374
2015 Chekabab SM, Silverman RJ, Lafayette SL, Luo Y, Rousseau S, Nguyen D. Staphylococcus aureus Inhibits IL-8 Responses Induced by Pseudomonas aeruginosa in Airway Epithelial Cells. Plos One. 10: e0137753. PMID 26360879 DOI: 10.1371/Journal.Pone.0137753  0.449
2015 Dauletbaev N, Herscovitch K, Das M, Chen H, Bernier J, Matouk E, Bérubé J, Rousseau S, Lands LC. Down-regulation of IL-8 by high-dose vitamin D is specific to hyperinflammatory macrophages and involves mechanisms beyond up-regulation of DUSP1. British Journal of Pharmacology. 172: 4757-71. PMID 26178144 DOI: 10.1111/Bph.13249  0.328
2015 Trinh NT, Bilodeau C, Maillé É, Ruffin M, Quintal MC, Desrosiers MY, Rousseau S, Brochiero E. Deleterious impact of Pseudomonas aeruginosa on cystic fibrosis transmembrane conductance regulator function and rescue in airway epithelial cells. The European Respiratory Journal. 45: 1590-602. PMID 25792634 DOI: 10.1183/09031936.00076214  0.398
2015 Tiedje C, Lubas M, Tehrani M, Menon MB, Ronkina N, Rousseau S, Cohen P, Kotlyarov A, Gaestel M. p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex. Rna (New York, N.Y.). 21: 262-78. PMID 25525152 DOI: 10.1261/Rna.048090.114  0.31
2015 McGovern TK, Goldberger M, Allard B, Farahnak S, Hamamoto Y, O'Sullivan M, Hirota N, Martel G, Rousseau S, Martin JG. Neutrophils mediate airway hyperresponsiveness after chlorine-induced airway injury in the mouse. American Journal of Respiratory Cell and Molecular Biology. 52: 513-22. PMID 25192041 DOI: 10.1165/Rcmb.2013-0430Oc  0.39
2015 Chow SC, Gowing SD, Cools-Lartigue JJ, Chen CB, Berube J, Yoon HW, Chan CH, Rousseau MC, Bourdeau F, Giannias B, Roussel L, Qureshi ST, Rousseau S, Ferri LE. Gram negative bacteria increase non-small cell lung cancer metastasis via Toll-like receptor 4 activation and mitogen-activated protein kinase phosphorylation. International Journal of Cancer. Journal International Du Cancer. 136: 1341-50. PMID 25082668 DOI: 10.1002/Ijc.29111  0.425
2015 Jiang H, Najmeh S, Berube J, Leone A, Savage P, Giannias B, Rousseau S, Park M, Ferri LE. Abstract 3162: NOD1 augments cancer cell metastatic potential through p38 MAP kinase activation Immunology. 75: 3162-3162. DOI: 10.1158/1538-7445.Am2015-3162  0.361
2015 Dauletbaev N, Das M, Cammisano M, Kooi C, Leigh R, Beaudoin T, Rousseau S, Lands L. 125 Viral load is high despite preserved interferon-β response in rhinovirus-infected CF cells Journal of Cystic Fibrosis. 14: S89. DOI: 10.1016/S1569-1993(15)30302-7  0.383
2014 Al-Alwan LA, Chang Y, Rousseau S, Martin JG, Eidelman DH, Hamid Q. CXCL1 inhibits airway smooth muscle cell migration through the decoy receptor Duffy antigen receptor for chemokines. Journal of Immunology (Baltimore, Md. : 1950). 193: 1416-26. PMID 24981451 DOI: 10.4049/Jimmunol.1302860  0.426
2014 Jaworska J, Coulombe F, Downey J, Tzelepis F, Shalaby K, Tattoli I, Berube J, Rousseau S, Martin JG, Girardin SE, McCullers JA, Divangahi M. NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein. Proceedings of the National Academy of Sciences of the United States of America. 111: E2110-9. PMID 24799673 DOI: 10.1073/Pnas.1322118111  0.321
2014 Martel G, Rousseau S. TPL2 signalling: from Toll-like receptors-mediated ERK1/ERK2 activation to Cystic Fibrosis lung disease. The International Journal of Biochemistry & Cell Biology. 52: 146-51. PMID 24530836 DOI: 10.1016/J.Biocel.2014.02.002  0.461
2014 Zago M, Rico de Souza A, Hecht E, Rousseau S, Hamid Q, Eidelman DH, Baglole CJ. The NF-κB family member RelB regulates microRNA miR-146a to suppress cigarette smoke-induced COX-2 protein expression in lung fibroblasts Toxicology Letters. 226: 107-116. PMID 24472607 DOI: 10.1016/J.Toxlet.2014.01.020  0.3
2014 Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Giannias B, Rousseau S, Qureshi ST, Ferri LE. Abstract 1963: Toll-like receptor activation in bacterial pneumonia increases lung cancer cell adhesion and metastasis formation Cancer Research. 74: 1963-1963. DOI: 10.1158/1538-7445.Am2014-1963  0.38
2013 Martel G, Roussel L, Rousseau S. The protein kinases TPL2 and EGFR contribute to ERK1/ERK2 hyper-activation in CFTRΔF508-expressing airway epithelial cells exposed to Pseudomonas aeruginosa. Biochemical and Biophysical Research Communications. PMID 24513215 DOI: 10.1016/J.Bbrc.2013.10.030  0.448
2013 Martel G, Roussel L, Rousseau S. The protein kinases TPL2 and EGFR contribute to ERK1/ERK2 hyperactivation in CFTRΔF508-expressing airway epithelial cells exposed to Pseudomonas aeruginosa. Biochemical and Biophysical Research Communications. 441: 689-92. PMID 24404585  0.319
2013 Zago M, Sheridan JA, Nair P, Rico de Souza A, Gallouzi IE, Rousseau S, Di Marco S, Hamid Q, Eidelman DH, Baglole CJ. Aryl hydrocarbon receptor-dependent retention of nuclear HuR suppresses cigarette smoke-induced cyclooxygenase-2 expression independent of DNA-binding. Plos One. 8: e74953. PMID 24086407 DOI: 10.1371/Journal.Pone.0074953  0.357
2013 Al-Alwan LA, Chang Y, Mogas A, Halayko AJ, Baglole CJ, Martin JG, Rousseau S, Eidelman DH, Hamid Q. Differential roles of CXCL2 and CXCL3 and their receptors in regulating normal and asthmatic airway smooth muscle cell migration. Journal of Immunology (Baltimore, Md. : 1950). 191: 2731-41. PMID 23904157 DOI: 10.4049/Jimmunol.1203421  0.439
2013 Rousseau MC, Hsu RY, Spicer JD, McDonald B, Chan CH, Perera RM, Giannias B, Chow SC, Rousseau S, Law S, Ferri LE. Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory ability of human esophageal cancer cells in a selectin-dependent manner. Surgery. 154: 69-77. PMID 23809486 DOI: 10.1016/J.Surg.2013.03.006  0.336
2013 Martel G, Bérubé J, Rousseau S. The protein kinase TPL2 is essential for ERK1/ERK2 activation and cytokine gene expression in airway epithelial cells exposed to pathogen-associated molecular patterns (PAMPs). Plos One. 8: e59116. PMID 23527104 DOI: 10.1371/Journal.Pone.0059116  0.488
2013 Beaudoin T, LaFayette S, Roussel L, Bérubé J, Desrosiers M, Nguyen D, Rousseau S. The level of p38α mitogen-activated protein kinase activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa. The Journal of Infectious Diseases. 207: 1544-55. PMID 23402824 DOI: 10.1093/Infdis/Jit059  0.446
2013 Roussel L, Farias R, Rousseau S. IL-33 is expressed in epithelia from patients with cystic fibrosis and potentiates neutrophil recruitment. The Journal of Allergy and Clinical Immunology. 131: 913-6. PMID 23219168 DOI: 10.1016/J.Jaci.2012.10.019  0.334
2012 Beaudoin T, Lafayette S, Nguyen D, Rousseau S. Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells. Biochemical and Biophysical Research Communications. 428: 150-4. PMID 23068105 DOI: 10.1016/J.Bbrc.2012.10.030  0.444
2011 Roussel L, Robins S, Schachter A, Bérubé J, Hamid Q, Rousseau S. Steroids and extracellular signal-regulated kinase 1/2 activity suppress activating transcription factor 3 expression in patients with severe asthma. The Journal of Allergy and Clinical Immunology. 127: 1632-4. PMID 21514952 DOI: 10.1016/J.Jaci.2011.03.034  0.373
2011 Robins S, Roussel L, Schachter A, Risse PA, Mogas AK, Olivenstein R, Martin JG, Hamid Q, Rousseau S. Steroid-insensitive ERK1/2 activity drives CXCL8 synthesis and neutrophilia by airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 45: 984-90. PMID 21493783 DOI: 10.1165/Rcmb.2010-0450Oc  0.364
2011 Hsu RY, Chan CH, Spicer JD, Rousseau MC, Giannias B, Rousseau S, Ferri LE. LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. Cancer Research. 71: 1989-98. PMID 21363926 DOI: 10.1158/0008-5472.Can-10-2833  0.335
2011 Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid Q, Eidelman DH. TH17 cytokines induce human airway smooth muscle cell migration. The Journal of Allergy and Clinical Immunology. 127: 1046-53.e1-2. PMID 21345484 DOI: 10.1016/J.Jaci.2010.12.1117  0.383
2011 Roussel L, Martel G, Bérubé J, Rousseau S. P. aeruginosa drives CXCL8 synthesis via redundant toll-like receptors and NADPH oxidase in CFTR∆F508 airway epithelial cells. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 10: 107-13. PMID 21176887 DOI: 10.1016/J.Jcf.2010.11.005  0.423
2011 Desrosiers M, Mfuna-Endam L, Divoy C, Filali-Mouhim A, Tessier M, Mongrain V, Berthiamue Y, Rousseau S. Bioinformatic Analysis Of Epithelial Cell Gene Expression In Chronic Rhinosinusitis Identifies Constitutive Differences Between CRSwNP And CRSsNP The Journal of Allergy and Clinical Immunology. 127. DOI: 10.1016/J.Jaci.2010.12.1070  0.313
2010 Sabio G, Cerezo-Guisado MI, Del Reino P, Iñesta-Vaquera FA, Rousseau S, Arthur JS, Campbell DG, Centeno F, Cuenda A. p38gamma regulates interaction of nuclear PSF and RNA with the tumour-suppressor hDlg in response to osmotic shock. Journal of Cell Science. 123: 2596-604. PMID 20605917 DOI: 10.1242/Jcs.066514  0.34
2010 Bérubé J, Roussel L, Nattagh L, Rousseau S. Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa. The Journal of Biological Chemistry. 285: 22299-307. PMID 20460375 DOI: 10.1074/Jbc.M109.098566  0.438
2010 Roussel L, Houle F, Chan C, Yao Y, Bérubé J, Olivenstein R, Martin JG, Huot J, Hamid Q, Ferri L, Rousseau S. IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. Journal of Immunology (Baltimore, Md. : 1950). 184: 4531-7. PMID 20228195 DOI: 10.4049/Jimmunol.0903162  0.609
2010 Côté MC, Lavoie JR, Houle F, Poirier A, Rousseau S, Huot J. Regulation of vascular endothelial growth factor-induced endothelial cell migration by LIM kinase 1-mediated phosphorylation of annexin 1. The Journal of Biological Chemistry. 285: 8013-21. PMID 20061392 DOI: 10.1074/Jbc.M109.098665  0.618
2010 Roussel L, Rousseau S. IL-17 primes airway epithelial cells lacking functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) to increase NOD1 responses. Biochemical and Biophysical Research Communications. 391: 505-9. PMID 19931506 DOI: 10.1016/J.Bbrc.2009.11.088  0.401
2010 Hsu RY, Chan CH, Spicer JD, Rousseau MC, Perera R, Giannias B, Rousseau S, Ferri LE. Abstract 5279: LPS-TLR4 binding increases metastatic potential of colorectal cancer cells Cancer Research. 70: 5279-5279. DOI: 10.1158/1538-7445.Am10-5279  0.343
2009 Bérubé J, Bourdon C, Yao Y, Rousseau S. Distinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells. Cellular Signalling. 21: 448-56. PMID 19121387 DOI: 10.1016/J.Cellsig.2008.12.001  0.439
2008 Rousseau S, Papoutsopoulou M, Symons A, Cook D, Lucocq JM, Prescott AR, O'Garra A, Ley SC, Cohen P. TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. Journal of Cell Science. 121: 149-54. PMID 18187448 DOI: 10.1242/Jcs.018671  0.346
2008 Yang HT, Cohen P, Rousseau S. IL-1β-stimulated activation of ERK1/2 and p38α MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-α in HeLa cells Cellular Signalling. 20: 375-380. PMID 18065201 DOI: 10.1016/J.Cellsig.2007.10.025  0.402
2007 Cuenda A, Rousseau S. p38 MAP-kinases pathway regulation, function and role in human diseases. Biochimica Et Biophysica Acta. 1773: 1358-75. PMID 17481747 DOI: 10.1016/J.Bbamcr.2007.03.010  0.427
2006 Morton S, Yang HT, Moleleki N, Campbell DG, Cohen P, Rousseau S. Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ. The Biochemical Journal. 399: 265-73. PMID 16848763 DOI: 10.1042/Bj20060681  0.393
2006 Rousseau S, Dolado I, Beardmore V, Shpiro N, Marquez R, Nebreda AR, Arthur JS, Case LM, Tessier-Lavigne M, Gaestel M, Cuenda A, Cohen P. CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway. Cellular Signalling. 18: 1897-905. PMID 16574378 DOI: 10.1016/J.Cellsig.2006.02.006  0.444
2005 Buxadé M, Parra JL, Rousseau S, Shpiro N, Marquez R, Morrice N, Bain J, Espel E, Proud CG. The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1. Immunity. 23: 177-89. PMID 16111636 DOI: 10.1016/J.Immuni.2005.06.009  0.413
2005 Rousseau S, Peggie M, Campbell DG, Nebredaf AR, Cohen P. Nogo-B is a new physiological substrate for MAPKAP-K2 Biochemical Journal. 391: 433-440. PMID 16095439 DOI: 10.1042/Bj20050935  0.367
2003 Houle F, Rousseau S, Morrice N, Luc M, Mongrain S, Turner CE, Tanaka S, Moreau P, Huot J. Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing. Molecular Biology of the Cell. 14: 1418-32. PMID 12686598 DOI: 10.1091/Mbc.E02-04-0235  0.6
2002 Rousseau S, Morrice N, Peggie M, Campbell DG, Gaestel M, Cohen P. Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs. The Embo Journal. 21: 6505-14. PMID 12456657 DOI: 10.1093/Emboj/Cdf639  0.362
2000 Rousseau S, Houle F, Huot J. Integrating the VEGF signals leading to actin-based motility in vascular endothelial cells Trends in Cardiovascular Medicine. 10: 321-327. PMID 11369257 DOI: 10.1016/S1050-1738(01)00072-X  0.557
2000 Rousseau S, Houle F, Kotanides H, Witte L, Waltenberger J, Landry J, Huot J. Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase. The Journal of Biological Chemistry. 275: 10661-72. PMID 10744763 DOI: 10.1074/Jbc.275.14.10661  0.62
1999 Giroux S, Tremblay M, Bernard D, Cardin-Girard JF, Aubry S, Larouche L, Rousseau S, Huot J, Landry J, Jeannotte L, Charron J. Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta. Current Biology : Cb. 9: 369-72. PMID 10209122 DOI: 10.1016/S0960-9822(99)80164-X  0.615
1998 Huot J, Houle F, Rousseau S, Deschesnes RG, Shah GM, Landry J. SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis. The Journal of Cell Biology. 143: 1361-73. PMID 9832563 DOI: 10.1083/Jcb.143.5.1361  0.6
1997 Rousseau S, Houle F, Landry J, Huot J. P38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells Oncogene. 15: 2169-2177. PMID 9393975 DOI: 10.1038/Sj.Onc.1201380  0.63
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