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Nuska Tschammer, Ph.D. - Publications

Affiliations: 
2007 University of Central Florida, Orlando, FL, United States 
Area:
Molecular Biology, Bioinformatics Biology
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kolarič A, Švajger U, Tomašič T, Brox R, Frank T, Minovski N, Tschammer N, Anderluh M. Insight into structural requirements for selective and/or dual CXCR3 and CXCR4 allosteric modulators. European Journal of Medicinal Chemistry. 154: 68-90. PMID 29777988 DOI: 10.1016/j.ejmech.2018.05.013  0.455
2018 Brox R, Milanos L, Saleh N, Baumeister P, Buschauer A, Hofmann D, Heinrich MR, Clark T, Tschammer N. Molecular mechanisms of biased and probe-dependent signaling at CXCR3 induced by negative allosteric modulators. Molecular Pharmacology. PMID 29343553 DOI: 10.1124/Mol.117.110296  0.473
2017 Thum S, Kokornaczyk AK, Seki T, De Maria M, Ortiz Zacarias NV, de Vries H, Weiss C, Koch M, Schepmann D, Kitamura M, Tschammer N, Heitman LH, Junker A, Wünsch B. Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold. European Journal of Medicinal Chemistry. 135: 401-413. PMID 28463783 DOI: 10.1016/J.Ejmech.2017.04.046  0.514
2016 Frank T, Reichel A, Larsen O, Stilp AC, Rosenkilde MM, Stamminger T, Ozawa T, Tschammer N. Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28. Cell Communication and Signaling : Ccs. 14: 31. PMID 27955674 DOI: 10.1186/s12964-016-0154-x  0.308
2016 Milanos L, Saleh N, Kling RC, Kaindl J, Tschammer N, Clark T. Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3. Angewandte Chemie (International Ed. in English). PMID 27862735 DOI: 10.1002/Anie.201607831  0.493
2016 Calmet P, De Maria M, Harté E, Lamb D, Serrano-Vega M, Jazayeri A, Tschammer N, Alves ID. Real time monitoring of membrane GPCR reconstitution by plasmon waveguide resonance: on the role of lipids. Scientific Reports. 6: 36181. PMID 27824122 DOI: 10.1038/srep36181  0.345
2016 Tabor A, Weisenburger S, Banerjee A, Purkayastha N, Kaindl JM, Hübner H, Wei L, Grömer TW, Kornhuber J, Tschammer N, Birdsall NJ, Mashanov GI, Sandoghdar V, Gmeiner P. Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level. Scientific Reports. 6: 33233. PMID 27615810 DOI: 10.1038/Srep33233  0.668
2016 Tschammer N. Allosteric Modulators of the Class A G Protein Coupled Receptors. Advances in Experimental Medicine and Biology. 917: 185-207. PMID 27236557 DOI: 10.1007/978-3-319-32805-8_9  0.471
2016 Admas TH, Bernat V, Heinrich MR, Tschammer N. Development of Photoactivatable Allosteric Modulators for the Chemokine Receptor CXCR3. Chemmedchem. 11: 575-84. PMID 26880380 DOI: 10.1002/Cmdc.201500573  0.761
2016 Milanos L, Brox R, Frank T, Poklukar G, Palmisano R, Waibel R, Einsiedel J, Dürr M, Ivanović-Burmazović I, Larsen O, Hjortø GM, Rosenkilde MM, Tschammer N. Discovery and Characterization of Biased Allosteric Agonists of the Chemokine Receptor CXCR3. Journal of Medicinal Chemistry. 59: 2222-43. PMID 26862767 DOI: 10.1021/acs.jmedchem.5b01965  0.437
2015 Bernat V, Brox R, Heinrich MR, Auberson YP, Tschammer N. Ligand-biased and probe-dependent modulation of chemokine receptor CXCR3 signaling by negative allosteric modulators. Chemmedchem. 10: 566-74. PMID 25655398 DOI: 10.1002/Cmdc.201402507  0.749
2015 Schmidt D, Bernat V, Brox R, Tschammer N, Kolb P. Identifying modulators of CXC receptors 3 and 4 with tailored selectivity using multi-target docking. Acs Chemical Biology. 10: 715-24. PMID 25398025 DOI: 10.1021/Cb500577J  0.759
2014 Bernat V, Admas TH, Brox R, Heinemann FW, Tschammer N. Boronic acids as probes for investigation of allosteric modulation of the chemokine receptor CXCR3. Acs Chemical Biology. 9: 2664-77. PMID 25233453 DOI: 10.1021/Cb500678C  0.745
2014 Tschammer N. Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? Bioorganic & Medicinal Chemistry Letters. 24: 3744-7. PMID 25052428 DOI: 10.1016/j.bmcl.2014.06.082  0.411
2014 Kling RC, Tschammer N, Lanig H, Clark T, Gmeiner P. Active-state model of a dopamine D2 receptor-Gαi complex stabilized by aripiprazole-type partial agonists. Plos One. 9: e100069. PMID 24932547 DOI: 10.1371/Journal.Pone.0100069  0.656
2014 Fehler SK, Maschauer S, Höfling SB, Bartuschat AL, Tschammer N, Hübner H, Gmeiner P, Prante O, Heinrich MR. Fast and efficient (18) F-labeling by [(18) f]fluorophenylazocarboxylic esters. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 370-5. PMID 24339325 DOI: 10.1002/chem.201303409  0.368
2014 Kralj A, Kurt E, Tschammer N, Heinrich MR. Synthesis and biological evaluation of biphenyl amides that modulate the US28 receptor. Chemmedchem. 9: 151-68. PMID 24265151 DOI: 10.1002/cmdc.201300369  0.37
2013 Kralj A, Nguyen MT, Tschammer N, Ocampo N, Gesiotto Q, Heinrich MR, Phanstiel O. Development of flavonoid-based inverse agonists of the key signaling receptor US28 of human cytomegalovirus. Journal of Medicinal Chemistry. 56: 5019-32. PMID 23768434 DOI: 10.1021/jm4003457  0.42
2013 Sanna F, Ortner B, Hübner H, Löber S, Tschammer N, Gmeiner P. Discovery of dopamine D₄ receptor antagonists with planar chirality. Bioorganic & Medicinal Chemistry. 21: 1680-4. PMID 23428965 DOI: 10.1016/j.bmc.2013.01.065  0.608
2012 Bernat V, Heinrich MR, Baumeister P, Buschauer A, Tschammer N. Synthesis and application of the first radioligand targeting the allosteric binding pocket of chemokine receptor CXCR3. Chemmedchem. 7: 1481-9. PMID 22689503 DOI: 10.1002/Cmdc.201200184  0.759
2011 Koschatzky S, Tschammer N, Gmeiner P. Cross-receptor interactions between dopamine D2L and neurotensin NTS1 receptors modulate binding affinities of dopaminergics. Acs Chemical Neuroscience. 2: 308-16. PMID 22778874 DOI: 10.1021/cn200020y  0.649
2011 Kralj A, Wetzel A, Mahmoudian S, Stamminger T, Tschammer N, Heinrich MR. Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus. Bioorganic & Medicinal Chemistry Letters. 21: 5446-50. PMID 21784633 DOI: 10.1016/j.bmcl.2011.06.120  0.403
2011 Einsiedel J, Held C, Hervet M, Plomer M, Tschammer N, Hübner H, Gmeiner P. Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics. Journal of Medicinal Chemistry. 54: 2915-23. PMID 21446649 DOI: 10.1021/jm200006c  0.63
2011 Tschammer N, Elsner J, Goetz A, Ehrlich K, Schuster S, Ruberg M, Kühhorn J, Thompson D, Whistler J, Hübner H, Gmeiner P. Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. Journal of Medicinal Chemistry. 54: 2477-91. PMID 21388142 DOI: 10.1021/Jm101639T  0.672
2011 Löber S, Hübner H, Tschammer N, Gmeiner P. Recent advances in the search for D3- and D4-selective drugs: probes, models and candidates. Trends in Pharmacological Sciences. 32: 148-57. PMID 21232805 DOI: 10.1016/j.tips.2010.12.003  0.562
2011 Tschammer N, Bollinger S, Kenakin T, Gmeiner P. Histidine 6.55 is a major determinant of ligand-biased signaling in dopamine D2L receptor. Molecular Pharmacology. 79: 575-85. PMID 21163968 DOI: 10.1124/mol.110.068106  0.658
2010 Tschammer N, Dörfler M, Hübner H, Gmeiner P. Engineering a GPCR-ligand pair that simulates the activation of D(2L) by Dopamine. Acs Chemical Neuroscience. 1: 25-35. PMID 22778805 DOI: 10.1021/cn900001b  0.659
2010 Kittipatarin C, Tschammer N, Khaled AR. The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to interleukin-7. Immunology Letters. 131: 170-81. PMID 20433867 DOI: 10.1016/J.Imlet.2010.04.007  0.567
2010 Kittipatarin C, Tschammer N, Khaled AR. SS2-6 The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to Interleukin-7 Cytokine. 52: 14-14. DOI: 10.1016/J.Cyto.2010.07.061  0.362
2009 Ehrlich K, Götz A, Bollinger S, Tschammer N, Bettinetti L, Härterich S, Hübner H, Lanig H, Gmeiner P. Dopamine D2, D3, and D4 selective phenylpiperazines as molecular probes to explore the origins of subtype specific receptor binding. Journal of Medicinal Chemistry. 52: 4923-35. PMID 19606869 DOI: 10.1021/jm900690y  0.577
2009 Löber S, Tschammer N, Hübner H, Melis MR, Argiolas A, Gmeiner P. The azulene framework as a novel arene bioisostere: design of potent dopamine D4 receptor ligands inducing penile erection. Chemmedchem. 4: 325-8. PMID 19185034 DOI: 10.1002/cmdc.200800395  0.612
2008 Dörfler M, Tschammer N, Hamperl K, Hübner H, Gmeiner P. Novel D3 selective dopaminergics incorporating enyne units as nonaromatic catechol bioisosteres: synthesis, bioactivity, and mutagenesis studies. Journal of Medicinal Chemistry. 51: 6829-38. PMID 18834111 DOI: 10.1021/jm800895v  0.584
2008 Kaur N, Delcros JG, Imran J, Khaled A, Chehtane M, Tschammer N, Martin B, Phanstiel O. A comparison of chloroambucil- and xylene-containing polyamines leads to improved ligands for accessing the polyamine transport system. Journal of Medicinal Chemistry. 51: 1393-401. PMID 18281932 DOI: 10.1021/jm070794t  0.594
2007 Tschammer N, Selby TL, Khaled AR. 154 The Membrane-binding Activity of the Apoptotic Protein, BAX, is Regulated Through Novel Intermolecular Interactions Cytokine. 39: 42-43. DOI: 10.1016/J.Cyto.2007.07.159  0.623
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