| Year |
Citation |
Score |
| 2024 |
Gooding SW, Felth L, Foxall R, Rosa Z, Ireton K, Sall I, Gipoor J, Gaur A, King M, Dirks N, Whistler CA, Whistler JL. Deletion of arrestin-3 does not reduce drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration. Frontiers in Pharmacology. 15: 1438037. PMID 39391692 DOI: 10.3389/fphar.2024.1438037 |
0.84 |
|
| 2024 |
Dong C, Gowrishankar R, Jin Y, He XJ, Gupta A, Wang H, Sayar-Atasoy N, Flores RJ, Mahe K, Tjahjono N, Liang R, Marley A, Or Mizuno G, Lo DK, Sun Q, ... Whistler JL, et al. Unlocking opioid neuropeptide dynamics with genetically encoded biosensors. Nature Neuroscience. PMID 39009835 DOI: 10.1038/s41593-024-01697-1 |
0.654 |
|
| 2024 |
Gooding SW, Lewis E, Chau C, Sandhu S, Glienke J, Whistler JL. Nucleus accumbens sub-regions experience distinct dopamine release responses following acute and chronic morphine exposure. Biorxiv : the Preprint Server For Biology. PMID 39005415 DOI: 10.1101/2024.06.28.601282 |
0.795 |
|
| 2024 |
Sall IJ, Foxall R, Felth L, Maret S, Rosa Z, Gaur A, Calawa J, Pavlik N, Whistler J, Whistler CA. Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic voluntary morphine. Biorxiv : the Preprint Server For Biology. PMID 38659831 DOI: 10.1101/2024.04.15.589671 |
0.811 |
|
| 2024 |
Gooding SW, Felth L, Foxall R, Rosa Z, Ireton K, Sall I, Gipoor J, Gaur A, King M, Dirks N, Whistler CA, Whistler JL. Deletion of arrestin-3 does not improve compulsive drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration. Biorxiv : the Preprint Server For Biology. PMID 38562752 DOI: 10.1101/2023.03.30.534994 |
0.845 |
|
| 2023 |
Gooding SW, Whistler JL. A Balancing Act: Learning from the Past to Build a Future-Focused Opioid Strategy. Annual Review of Physiology. PMID 38029388 DOI: 10.1146/annurev-physiol-042022-015914 |
0.78 |
|
| 2023 |
Schamiloglu S, Lewis E, Keeshen CM, Hergarden AC, Bender KJ, Whistler JL. Arrestin-3 agonism at D3 dopamine receptors defines a subclass of second generation antipsychotics that promotes drug tolerance. Biological Psychiatry. PMID 36931452 DOI: 10.1016/j.biopsych.2023.03.006 |
0.811 |
|
| 2021 |
He L, Gooding SW, Lewis E, Felth LC, Gaur A, Whistler JL. Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34257415 DOI: 10.1038/s41386-021-01054-x |
0.846 |
|
| 2016 |
Johnson TA, Milan-Lobo L, Che T, Ferwerda M, Lambo E, McIntosh NL, Li F, He L, Lorig-Roach N, Crews P, Whistler JL. Identification of the first marine-derived opioid receptor "balanced" agonist with a signaling profile that resembles the endorphins. Acs Chemical Neuroscience. PMID 27744679 DOI: 10.1021/Acschemneuro.6B00167 |
0.676 |
|
| 2016 |
Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR. Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7925-35. PMID 27466337 DOI: 10.1523/Jneurosci.1493-16.2016 |
0.413 |
|
| 2016 |
Yang S, Ben-Shalom R, Ahn M, Liptak AT, van Rijn RM, Whistler JL, Bender KJ. β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment. Cell Reports. PMID 27452469 DOI: 10.1016/J.Celrep.2016.06.098 |
0.676 |
|
| 2016 |
Crowley NA, Bloodgood DW, Hardaway JA, Kendra AM, McCall JG, Al-Hasani R, McCall NM, Yu W, Schools ZL, Krashes MJ, Lowell BB, Whistler JL, Bruchas MR, Kash TL. Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit. Cell Reports. PMID 26997280 DOI: 10.1016/J.Celrep.2016.02.069 |
0.362 |
|
| 2014 |
Roed SN, Wismann P, Underwood CR, Kulahin N, Iversen H, Cappelen KA, Schäffer L, Lehtonen J, Hecksher-Soerensen J, Secher A, Mathiesen JM, Bräuner-Osborne H, Whistler JL, Knudsen SM, Waldhoer M. Real-time trafficking and signaling of the glucagon-like peptide-1 receptor. Molecular and Cellular Endocrinology. 382: 938-49. PMID 24275181 DOI: 10.1016/J.Mce.2013.11.010 |
0.73 |
|
| 2013 |
He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, ... Whistler JL, et al. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell. 154: 1085-99. PMID 23954414 DOI: 10.1016/J.Cell.2013.07.035 |
0.426 |
|
| 2013 |
Madhavan A, Argilli E, Bonci A, Whistler JL. Loss of D2 dopamine receptor function modulates cocaine-induced glutamatergic synaptic potentiation in the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12329-36. PMID 23884939 DOI: 10.1523/Jneurosci.0809-13.2013 |
0.643 |
|
| 2013 |
van Rijn RM, Defriel JN, Whistler JL. Pharmacological traits of delta opioid receptors: pitfalls or opportunities? Psychopharmacology. 228: 1-18. PMID 23649885 DOI: 10.1007/S00213-013-3129-2 |
0.756 |
|
| 2013 |
Milan-Lobo L, Enquist J, van Rijn RM, Whistler JL. Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism. Plos One. 8: e58362. PMID 23554887 DOI: 10.1371/Journal.Pone.0058362 |
0.849 |
|
| 2013 |
Harvey JH, van Rijn RM, Whistler JL. A FLIPR assay for evaluating agonists and antagonists of GPCR heterodimers. Methods in Molecular Biology (Clifton, N.J.). 995: 43-54. PMID 23494371 DOI: 10.1007/978-1-62703-345-9_4 |
0.676 |
|
| 2013 |
Goldsmith JR, Perez-Chanona E, Yadav PN, Whistler J, Roth B, Jobin C. Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling. The American Journal of Pathology. 182: 776-85. PMID 23291213 DOI: 10.1016/J.Ajpath.2012.11.021 |
0.407 |
|
| 2013 |
van Rijn RM, Harvey JH, Brissett DI, DeFriel JN, Whistler JL. Novel screening assay for the selective detection of G-protein-coupled receptor heteromer signaling. The Journal of Pharmacology and Experimental Therapeutics. 344: 179-88. PMID 23097213 DOI: 10.1124/Jpet.112.198655 |
0.763 |
|
| 2013 |
Tschische P, Madhavan A, Athiligam J, Milan-Lobo L, Thompson D, Wilbrecht L, Whistler JL. Trafficking of the D2 Dopamine Receptor Promotes Drug-Induced Changes in Neuronal and Behavioral Plasticity Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 97-98. DOI: 10.1016/B978-0-12-800044-1.00084-2 |
0.695 |
|
| 2012 |
Harvey JH, Long DH, England PM, Whistler JL. Tuned-Affinity Bivalent Ligands for the Characterization of Opioid Receptor Heteromers. Acs Medicinal Chemistry Letters. 3: 640-644. PMID 23585918 DOI: 10.1021/Ml300083P |
0.544 |
|
| 2012 |
Enquist J, Ferwerda M, Madhavan A, Hok D, Whistler JL. Chronic ethanol potentiates the effect of neuropeptide s in the basolateral amygdala and shows increased anxiolytic and anti-depressive effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2436-45. PMID 22739468 DOI: 10.1038/Npp.2012.102 |
0.76 |
|
| 2012 |
Albada HB, Wieberneit F, Dijkgraaf I, Harvey JH, Whistler JL, Stoll R, Metzler-Nolte N, Fish RH. The chemoselective reactions of tyrosine-containing G-protein-coupled receptor peptides with [Cp*Rh(H2O)3](OTf)2, including 2D NMR structures and the biological consequences. Journal of the American Chemical Society. 134: 10321-4. PMID 22671299 DOI: 10.1021/Ja303010K |
0.323 |
|
| 2012 |
Schröder R, Xue L, Konya V, Martini L, Kampitsch N, Whistler JL, Ulven T, Heinemann A, Pettipher R, Kostenis E. PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2. Plos One. 7: e33329. PMID 22442685 DOI: 10.1371/Journal.Pone.0033329 |
0.614 |
|
| 2012 |
Brissett DI, Whistler JL, van Rijn RM. Contribution of mu and delta opioid receptors to the pharmacological profile of kappa opioid receptor subtypes. European Journal of Pain (London, England). 16: 327-37. PMID 22337177 DOI: 10.1002/J.1532-2149.2011.00022.X |
0.795 |
|
| 2012 |
Whistler JL. Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence. 121: 189-204. PMID 22226706 DOI: 10.1016/J.Drugalcdep.2011.10.031 |
0.534 |
|
| 2012 |
Enquist J, Ferwerda M, Milan-Lobo L, Whistler JL. Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice. The Journal of Pharmacology and Experimental Therapeutics. 340: 386-92. PMID 22062352 DOI: 10.1124/Jpet.111.187583 |
0.831 |
|
| 2012 |
van Rijn RM, Brissett DI, Whistler JL. Distinctive modulation of ethanol place preference by delta opioid receptor-selective agonists. Drug and Alcohol Dependence. 122: 156-9. PMID 22018601 DOI: 10.1016/J.Drugalcdep.2011.09.024 |
0.687 |
|
| 2012 |
van Rijn RM, Brissett DI, Whistler JL. Emergence of functional spinal delta opioid receptors after chronic ethanol exposure. Biological Psychiatry. 71: 232-8. PMID 21889123 DOI: 10.1016/J.Biopsych.2011.07.015 |
0.737 |
|
| 2012 |
Kargl J, Balenga NA, Platzer W, Martini L, Whistler JL, Waldhoer M. The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55. British Journal of Pharmacology. 165: 2611-9. PMID 21718301 DOI: 10.1111/J.1476-5381.2011.01562.X |
0.819 |
|
| 2012 |
Goldsmith JR, Chanona EP, Yadav PN, Whistler JL, Roth B, Jobin C. Sa1939 Intestinal Epithelial Cell (IEC)-Derived Mu-Opioid Signaling is Protective Against Ischemia Reperfusion (I/R) Induced Injury Gastroenterology. 142: S-364. DOI: 10.1016/S0016-5085(12)61373-0 |
0.372 |
|
| 2011 |
Kühhorn J, Götz A, Hübner H, Thompson D, Whistler J, Gmeiner P. Development of a bivalent dopamine D₂ receptor agonist. Journal of Medicinal Chemistry. 54: 7911-9. PMID 21999579 DOI: 10.1021/Jm2009919 |
0.657 |
|
| 2011 |
Berger AC, Whistler JL. Morphine-induced mu opioid receptor trafficking enhances reward yet prevents compulsive drug use. Embo Molecular Medicine. 3: 385-97. PMID 21656686 DOI: 10.1002/Emmm.201100144 |
0.733 |
|
| 2011 |
He L, Whistler JL. Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosis. Plos One. 6: e19372. PMID 21602922 DOI: 10.1371/Journal.Pone.0019372 |
0.625 |
|
| 2011 |
Enquist J, Kim JA, Bartlett S, Ferwerda M, Whistler JL. A novel knock-in mouse reveals mechanistically distinct forms of morphine tolerance. The Journal of Pharmacology and Experimental Therapeutics. 338: 633-40. PMID 21562138 DOI: 10.1124/Jpet.111.179754 |
0.83 |
|
| 2011 |
Milan-Lobo L, Whistler JL. Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor trafficking. The Journal of Pharmacology and Experimental Therapeutics. 337: 868-75. PMID 21422164 DOI: 10.1124/Jpet.111.179093 |
0.655 |
|
| 2011 |
Tschammer N, Elsner J, Goetz A, Ehrlich K, Schuster S, Ruberg M, Kühhorn J, Thompson D, Whistler J, Hübner H, Gmeiner P. Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. Journal of Medicinal Chemistry. 54: 2477-91. PMID 21388142 DOI: 10.1021/Jm101639T |
0.628 |
|
| 2011 |
Thompson D, Whistler JL. Trafficking properties of the D5 dopamine receptor. Traffic (Copenhagen, Denmark). 12: 644-56. PMID 21348911 DOI: 10.1111/J.1600-0854.2011.01179.X |
0.675 |
|
| 2011 |
Thompson D, Whistler JL. Dopamine D(3) receptors are down-regulated following heterologous endocytosis by a specific interaction with G protein-coupled receptor-associated sorting protein-1. The Journal of Biological Chemistry. 286: 1598-608. PMID 21030592 DOI: 10.1074/Jbc.M110.158345 |
0.625 |
|
| 2011 |
Kargl J, Balenga NA, Whistler JL, Waldhoer M. The G protein-coupled receptor-associated protein 1 (GASP-1) regulates rimonabant-induced downregulation of GPR55 Bmc Pharmacology. 11: A57. DOI: 10.1186/1471-2210-11-S2-A57 |
0.791 |
|
| 2010 |
Kargl J, Balenga N, Platzer W, Martini L, Whistler J, Waldhoer M. The trafficking of GPR55 is regulated by the G protein-coupled receptor-associated sorting protein 1 Bmc Pharmacology. 10: 1-1. PMID 21092347 DOI: 10.1186/1471-2210-10-S1-A1 |
0.838 |
|
| 2010 |
Madhavan A, Bonci A, Whistler JL. Opioid-Induced GABA potentiation after chronic morphine attenuates the rewarding effects of opioids in the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14029-35. PMID 20962224 DOI: 10.1523/Jneurosci.3366-10.2010 |
0.696 |
|
| 2010 |
Moser E, Kargl J, Whistler JL, Waldhoer M, Tschische P. G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors. Pharmacology. 86: 22-9. PMID 20693822 DOI: 10.1159/000314161 |
0.774 |
|
| 2010 |
van Rijn RM, Brissett DI, Whistler JL. Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety. The Journal of Pharmacology and Experimental Therapeutics. 335: 133-9. PMID 20605909 DOI: 10.1124/Jpet.110.170969 |
0.663 |
|
| 2010 |
Thompson D, Martini L, Whistler JL. Altered ratio of D1 and D2 dopamine receptors in mouse striatum is associated with behavioral sensitization to cocaine. Plos One. 5: e11038. PMID 20543951 DOI: 10.1371/Journal.Pone.0011038 |
0.7 |
|
| 2010 |
Berger AC, Whistler JL. How to design an opioid drug that causes reduced tolerance and dependence. Annals of Neurology. 67: 559-69. PMID 20437553 DOI: 10.1002/Ana.22002 |
0.753 |
|
| 2010 |
Bonde MM, Yao R, Ma JN, Madabushi S, Haunsø S, Burstein ES, Whistler JL, Sheikh SP, Lichtarge O, Hansen JL. An angiotensin II type 1 receptor activation switch patch revealed through evolutionary trace analysis. Biochemical Pharmacology. 80: 86-94. PMID 20227396 DOI: 10.1016/J.Bcp.2010.03.006 |
0.506 |
|
| 2010 |
Madhavan A, He L, Stuber GD, Bonci A, Whistler JL. micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3276-86. PMID 20203187 DOI: 10.1523/Jneurosci.4634-09.2010 |
0.726 |
|
| 2010 |
Martini L, Thompson D, Kharazia V, Whistler JL. Differential regulation of behavioral tolerance to WIN55,212-2 by GASP1. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1363-73. PMID 20164830 DOI: 10.1038/Npp.2010.6 |
0.862 |
|
| 2010 |
Henstridge CM, Balenga NA, Schröder R, Kargl JK, Platzer W, Martini L, Arthur S, Penman J, Whistler JL, Kostenis E, Waldhoer M, Irving AJ. GPR55 ligands promote receptor coupling to multiple signalling pathways. British Journal of Pharmacology. 160: 604-14. PMID 20136841 DOI: 10.1111/J.1476-5381.2009.00625.X |
0.781 |
|
| 2010 |
Tschische P, Moser E, Thompson D, Vischer HF, Parzmair GP, Pommer V, Platzer W, Schwarzbraun T, Schaider H, Smit MJ, Martini L, Whistler JL, Waldhoer M. The G-protein coupled receptor associated sorting protein GASP-1 regulates the signalling and trafficking of the viral chemokine receptor US28. Traffic (Copenhagen, Denmark). 11: 660-74. PMID 20102549 DOI: 10.1111/J.1600-0854.2010.01045.X |
0.813 |
|
| 2010 |
van Rijn RM, Whistler JL, Waldhoer M. Opioid-receptor-heteromer-specific trafficking and pharmacology. Current Opinion in Pharmacology. 10: 73-9. PMID 19846340 DOI: 10.1016/J.Coph.2009.09.007 |
0.862 |
|
| 2009 |
Moser E, Tschische P, Platzer W, Pommer V, Thompson D, Schaider H, Martini L, Whistler J, Waldhoer M. The targeting of US28 is dependent on GASP-1 Bmc Pharmacology. 9: 1-1. PMID 25410016 DOI: 10.1186/1471-2210-9-S2-A1 |
0.751 |
|
| 2009 |
He L, Kim JA, Whistler JL. Biomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant mu-opioid receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4327-34. PMID 19679639 DOI: 10.1096/Fj.09-133223 |
0.646 |
|
| 2009 |
van Rijn RM, Whistler JL. The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intake. Biological Psychiatry. 66: 777-84. PMID 19576572 DOI: 10.1016/J.Biopsych.2009.05.019 |
0.776 |
|
| 2009 |
Ravindranathan A, Joslyn G, Robertson M, Schuckit MA, Whistler JL, White RL. Functional characterization of human variants of the mu-opioid receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 106: 10811-6. PMID 19528663 DOI: 10.1073/Pnas.0904509106 |
0.615 |
|
| 2009 |
He L, Kim J, Ou C, McFadden W, van Rijn RM, Whistler JL. Methadone antinociception is dependent on peripheral opioid receptors. The Journal of Pain : Official Journal of the American Pain Society. 10: 369-79. PMID 19327642 DOI: 10.1016/J.Jpain.2008.09.011 |
0.755 |
|
| 2009 |
Wallace MJ, Newton PM, McMahon T, Connolly J, Huibers A, Whistler J, Messing RO. PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1733-42. PMID 19158669 DOI: 10.1038/Npp.2008.230 |
0.512 |
|
| 2009 |
Schröder R, Merten N, Mathiesen JM, Martini L, Kruljac-Letunic A, Krop F, Blaukat A, Fang Y, Tran E, Ulven T, Drewke C, Whistler J, Pardo L, Gomeza J, Kostenis E. The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. The Journal of Biological Chemistry. 284: 1324-36. PMID 19010788 DOI: 10.1074/Jbc.M806867200 |
0.689 |
|
| 2009 |
Kargl J, Balenga N, Martini L, Whistler J, Waldhoer M. Interactions of the G protein-coupled receptor-associated sorting proteins (GASP) 1 and 2 with the novel cannabinoid receptor GPR55 Bmc Pharmacology. 9: A5. DOI: 10.1186/1471-2210-9-S2-A5 |
0.792 |
|
| 2009 |
Tschische P, Moser E, Thompson D, Platzer W, Vischer H, Smit MJ, Schaider H, Martini L, Whistler J, Waldhoer M. The sorting protein GASP-1 regulates the constitutive signaling capacity of the virally encoded chemokine receptor US28 Bmc Pharmacology. 9: A4. DOI: 10.1186/1471-2210-9-S2-A4 |
0.771 |
|
| 2008 |
van Rijn RM, Whistler JL. The only way is up: preventing opioid tolerance by promoting cell surface expression of MOR-DOR heterodimers? Molecular Interventions. 8: 277-80. PMID 19144899 DOI: 10.1124/Mi.8.6.4 |
0.692 |
|
| 2008 |
Kim JA, Bartlett S, He L, Nielsen CK, Chang AM, Kharazia V, Waldhoer M, Ou CJ, Taylor S, Ferwerda M, Cado D, Whistler JL. Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence. Current Biology : Cb. 18: 129-35. PMID 18207746 DOI: 10.1016/J.Cub.2007.12.057 |
0.863 |
|
| 2008 |
Xia YF, He L, Whistler JL, Hjelmstad GO. Acute amphetamine exposure selectively desensitizes kappa-opioid receptors in the nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 892-900. PMID 17551543 DOI: 10.1038/Sj.Npp.1301463 |
0.653 |
|
| 2008 |
Kargl J, Balenga N, Martini L, Whistler J, Waldhoer M. Interactions of the G protein-coupled receptor-associated sorting proteins (GASP) 1 and 2 with the novel cannabinoid receptor GPR55 Bmc Pharmacology. 8: A16. DOI: 10.1186/1471-2210-9-S2-A5 |
0.829 |
|
| 2008 |
Tschische P, Whistler J, Thompson D, Martini L, Waldhoer M. The role of GASP in the post-endocytic sorting and signaling of virally encoded chemokine receptor US28 Bmc Pharmacology. 8: A3. DOI: 10.1186/1471-2210-8-S1-A3 |
0.836 |
|
| 2007 |
Martini L, Whistler JL. The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence. Current Opinion in Neurobiology. 17: 556-64. PMID 18068348 DOI: 10.1016/J.Conb.2007.10.004 |
0.793 |
|
| 2007 |
Thompson D, Pusch M, Whistler JL. Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors. The Journal of Biological Chemistry. 282: 29178-85. PMID 17635908 DOI: 10.1074/Jbc.M704014200 |
0.709 |
|
| 2007 |
Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. A molecular basis of analgesic tolerance to cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4165-77. PMID 17428994 DOI: 10.1523/Jneurosci.5648-06.2007 |
0.742 |
|
| 2007 |
Lasek AW, Janak PH, He L, Whistler JL, Heberlein U. Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice. Genes, Brain, and Behavior. 6: 728-35. PMID 17428267 DOI: 10.1111/J.1601-183X.2007.00303.X |
0.423 |
|
| 2007 |
He L, Whistler JL. The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain. Pharmacology. 79: 193-202. PMID 17356311 DOI: 10.1159/000100893 |
0.649 |
|
| 2007 |
Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, Lee JH, Freissmuth C, Whistler JL. Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 802-11. PMID 17197383 DOI: 10.1096/Fj.06-7132Com |
0.853 |
|
| 2007 |
Enquist J, Skröder C, Whistler JL, Leeb-Lundberg LM. Kinins promote B2 receptor endocytosis and delay constitutive B1 receptor endocytosis. Molecular Pharmacology. 71: 494-507. PMID 17110500 DOI: 10.1124/Mol.106.030858 |
0.843 |
|
| 2007 |
Thallinger C, Poeppl W, Pratscher B, Mayerhofer M, Valent P, He L, Whistler JL, Koseler A, Ilcol YO, Ulus IH, Ortega-Varela LF, Herrera JE, Caram-Salas NL, Rocha-González HI, Granados-Soto V, et al. Subject Index Vol. 79, 2007 Pharmacology. 79: 260-264. DOI: 10.1159/000103508 |
0.312 |
|
| 2005 |
Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL. Dopamine responsiveness is regulated by targeted sorting of D2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 102: 11521-6. PMID 16049099 DOI: 10.1073/Pnas.0502418102 |
0.809 |
|
| 2005 |
He L, Whistler JL. An opiate cocktail that reduces morphine tolerance and dependence. Current Biology : Cb. 15: 1028-33. PMID 15936273 DOI: 10.1016/J.Cub.2005.04.052 |
0.682 |
|
| 2005 |
Waldhoer M, Fong J, Jones RM, Lunzer MM, Sharma SK, Kostenis E, Portoghese PS, Whistler JL. A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers. Proceedings of the National Academy of Sciences of the United States of America. 102: 9050-5. PMID 15932946 DOI: 10.1073/Pnas.0501112102 |
0.804 |
|
| 2005 |
Kostenis E, Martini L, Ellis J, Waldhoer M, Heydorn A, Rosenkilde MM, Norregaard PK, Jorgensen R, Whistler JL, Milligan G. A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity. The Journal of Pharmacology and Experimental Therapeutics. 313: 78-87. PMID 15615862 DOI: 10.1124/Jpet.104.080424 |
0.787 |
|
| 2004 |
Heydorn A, Søndergaard BP, Ersbøll B, Holst B, Nielsen FC, Haft CR, Whistler J, Schwartz TW. A library of 7TM receptor C-terminal tails: Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP) Journal of Biological Chemistry. 279: 54291-54303. PMID 15452121 DOI: 10.1074/Jbc.M406169200 |
0.555 |
|
| 2004 |
Waldhoer M, Bartlett SE, Whistler JL. Opioid receptors. Annual Review of Biochemistry. 73: 953-90. PMID 15189164 DOI: 10.1146/annurev.biochem.73.011303.073940 |
0.794 |
|
| 2003 |
Waldhoer M, Casarosa P, Rosenkilde MM, Smit MJ, Leurs R, Whistler JL, Schwartz TW. The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis. The Journal of Biological Chemistry. 278: 19473-82. PMID 12646575 DOI: 10.1074/Jbc.M213179200 |
0.781 |
|
| 2002 |
Bartlett SE, Whistler JL. The near-death experience of delta opioid receptors leads to new drug targets. Molecular Interventions. 2: 134-6. PMID 14993372 DOI: 10.1124/Mi.2.3.134 |
0.535 |
|
| 2002 |
Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, Bourne HR. Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic (Copenhagen, Denmark). 3: 866-77. PMID 12453150 DOI: 10.1034/J.1600-0854.2002.31203.X |
0.714 |
|
| 2002 |
Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M. Modulation of postendocytic sorting of G protein-coupled receptors. Science (New York, N.Y.). 297: 615-20. PMID 12142540 DOI: 10.1126/Science.1073308 |
0.857 |
|
| 2002 |
Alvarez VA, Arttamangkul S, Dang V, Salem A, Whistler JL, Von Zastrow M, Grandy DK, Williams JT. mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5769-76. PMID 12097530 DOI: 10.1523/Jneurosci.22-13-05769.2002 |
0.741 |
|
| 2002 |
He L, Fong J, von Zastrow M, Whistler JL. Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization. Cell. 108: 271-82. PMID 11832216 DOI: 10.1016/S0092-8674(02)00613-X |
0.755 |
|
| 2001 |
Finn AK, Whistler JL. Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal. Neuron. 32: 829-39. PMID 11738029 DOI: 10.1016/S0896-6273(01)00517-7 |
0.873 |
|
| 2001 |
Whistler JL, Tsao P, von Zastrow M. A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes. The Journal of Biological Chemistry. 276: 34331-8. PMID 11443128 DOI: 10.1074/Jbc.M104627200 |
0.847 |
|
| 2001 |
Ungless MA, Whistler JL, Malenka RC, Bonci A. Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature. 411: 583-7. PMID 11385572 DOI: 10.1038/35079077 |
0.317 |
|
| 2000 |
Whistler J, Beattie E, von Zastrow M. Tales from the crypt: evidence for heptahelical receptor signaling in the endocytic pathway. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe1. PMID 11752604 DOI: 10.1126/Stke.2000.47.Pe1 |
0.685 |
|
| 1999 |
Whistler JL, Chuang HH, Chu P, Jan LY, von Zastrow M. Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron. 23: 737-46. PMID 10482240 DOI: 10.1016/S0896-6273(01)80032-5 |
0.747 |
|
| 1999 |
Whistler JL, von Zastrow M. Dissociation of functional roles of dynamin in receptor-mediated endocytosis and mitogenic signal transduction. The Journal of Biological Chemistry. 274: 24575-8. PMID 10455121 DOI: 10.1074/Jbc.274.35.24575 |
0.729 |
|
| 1998 |
Whistler JL, von Zastrow M. Morphine-activated opioid receptors elude desensitization by beta-arrestin. Proceedings of the National Academy of Sciences of the United States of America. 95: 9914-9. PMID 9707575 DOI: 10.1073/Pnas.95.17.9914 |
0.772 |
|
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