Year |
Citation |
Score |
2016 |
Zhang Y, Mantravadi PK, Jobbagy S, Bao W, Koh JT. Antagonizing the Androgen Receptor with a Biomimetic Acyltransferase. Acs Chemical Biology. PMID 27548116 DOI: 10.1021/Acschembio.6B00659 |
0.768 |
|
2016 |
Cadieux CL, Wang H, Zhang Y, Koenig JA, Shih TM, McDonough J, Koh J, Cerasoli D. Probing the Activity of a Non-Oxime Reactivator for Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents. Chemico-Biological Interactions. PMID 27062893 DOI: 10.1016/J.Cbi.2016.04.002 |
0.736 |
|
2012 |
Ceo LM, Koh JT. Photocaged DNA provides new levels of transcription control. Chembiochem : a European Journal of Chemical Biology. 13: 511-3. PMID 22271631 DOI: 10.1002/Cbic.201100683 |
0.751 |
|
2010 |
Jain D, Koh JT. A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements. Bioorganic & Medicinal Chemistry Letters. 20: 5258-61. PMID 20659801 DOI: 10.1016/J.Bmcl.2010.06.151 |
0.77 |
|
2010 |
Sauers DJ, Temburni MK, Biggins JB, Ceo LM, Galileo DS, Koh JT. Light-activated gene expression directs segregation of co-cultured cells in vitro. Acs Chemical Biology. 5: 313-20. PMID 20050613 DOI: 10.1021/Cb9002305 |
0.642 |
|
2008 |
Hassan AQ, Koh JT. Selective chemical rescue of a thyroid-hormone-receptor mutant, TRbeta(H435Y), identified in pituitary carcinoma and resistance to thyroid hormone. Angewandte Chemie (International Ed. in English). 47: 7280-3. PMID 18683837 DOI: 10.1002/Anie.200801742 |
0.329 |
|
2008 |
Zheng J, Hashimoto A, Putnam M, Miller K, Koh JT. Development of a thyroid hormone receptor targeting conjugate. Bioconjugate Chemistry. 19: 1227-34. PMID 18507428 DOI: 10.1021/Bc8000326 |
0.788 |
|
2007 |
Koh JT, Zheng J. The new biomimetic chemistry: artificial transcription factors. Acs Chemical Biology. 2: 599-601. PMID 17894442 DOI: 10.1021/Cb700183S |
0.75 |
|
2007 |
Biggins JB, Hashimoto A, Koh JT. Photocaged agonist for an analogue-specific form of the vitamin D receptor. Chembiochem : a European Journal of Chemical Biology. 8: 799-803. PMID 17393546 DOI: 10.1002/Cbic.200600497 |
0.744 |
|
2007 |
Posner GH, Suh BC, Petersen KS, Dolan P, Agoston ES, Kensler TW, Koh JT, Peleg S. Difluoromethyl analogs of the natural hormone 1α,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation Journal of Steroid Biochemistry and Molecular Biology. 103: 213-221. PMID 17218093 DOI: 10.1016/J.Jsbmb.2006.12.024 |
0.326 |
|
2007 |
Biggins JB, Koh JT. Chemical biology of steroid and nuclear hormone receptors. Current Opinion in Chemical Biology. 11: 99-110. PMID 17188557 DOI: 10.1016/J.Cbpa.2006.10.042 |
0.723 |
|
2006 |
Fotos JS, Patel VP, Karin NJ, Temburni MK, Koh JT, Galileo DS. Automated time-lapse microscopy and high-resolution tracking of cell migration. Cytotechnology. 51: 7-19. PMID 19002890 DOI: 10.1007/S10616-006-9006-7 |
0.764 |
|
2006 |
Hassan AQ, Koh JT. A functionally orthogonal ligand-receptor pair created by targeting the allosteric mechanism of the thyroid hormone receptor. Journal of the American Chemical Society. 128: 8868-74. PMID 16819881 DOI: 10.1021/ja060760v |
0.332 |
|
2005 |
Link KH, Shi Y, Koh JT. Light activated recombination. Journal of the American Chemical Society. 127: 13088-9. PMID 16173704 DOI: 10.1021/Ja0531226 |
0.789 |
|
2005 |
Koh JT, Biggins JB. Ligand-receptor engineering and its application towards the complementation of genetic disease and target identification. Current Topics in Medicinal Chemistry. 5: 413-20. PMID 15892683 DOI: 10.2174/1568026053828420 |
0.681 |
|
2005 |
Hashimoto A, Shi Y, Drake K, Koh JT. Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRbeta(R320H): a tailor-made approach toward the treatment of resistance to thyroid hormone. Bioorganic & Medicinal Chemistry. 13: 3627-39. PMID 15862991 DOI: 10.1016/J.Bmc.2005.03.040 |
0.617 |
|
2005 |
Shi Y, Ye H, Link KH, Putnam MC, Hubner I, Dowdell S, Koh JT. Mutant-selective thyromimetics for the chemical rescue of thyroid hormone receptor mutants associated with resistance to thyroid hormone. Biochemistry. 44: 4612-26. PMID 15779888 DOI: 10.1021/Bi0482349 |
0.758 |
|
2005 |
Koh J. Spatial control of protein synthesis Chemistry and Biology. 12: 613-614. DOI: 10.1016/J.Chembiol.2005.06.006 |
0.305 |
|
2004 |
Link KH, Cruz FG, Ye HF, O'reilly KE, Dowdell S, Koh JT. Photo-caged agonists of the nuclear receptors RARgamma and TRbeta provide unique time-dependent gene expression profiles for light-activated gene patterning. Bioorganic & Medicinal Chemistry. 12: 5949-59. PMID 15498671 DOI: 10.1016/J.Bmc.2004.08.022 |
0.799 |
|
2004 |
Shi Y, Koh JT. Light-activated transcription and repression by using photocaged SERMs. Chembiochem : a European Journal of Chemical Biology. 5: 788-96. PMID 15174161 DOI: 10.1002/Cbic.200300823 |
0.661 |
|
2002 |
Swann SL, Bergh JJ, Farach-Carson MC, Koh JT. Rational design of vitamin D3 analogues which selectively restore activity to a vitamin D receptor mutant associated with rickets. Organic Letters. 4: 3863-6. PMID 12599478 DOI: 10.1021/ol0266931 |
0.746 |
|
2002 |
Swann SL, Bergh J, Farach-Carson MC, Ocasio CA, Koh JT. Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor. Journal of the American Chemical Society. 124: 13795-805. PMID 12431109 DOI: 10.1021/Ja0268377 |
0.775 |
|
2002 |
Shi Y, Koh JT. Functionally orthogonal ligand-receptor pairs for the selective regulation of gene expression generated by manipulation of charged residues at the ligand-receptor interface of ER alpha and ER beta. Journal of the American Chemical Society. 124: 6921-8. PMID 12059215 DOI: 10.1021/Ja016897X |
0.572 |
|
2002 |
Koh JT. Engineering selectivity and discrimination into ligand-receptor interfaces. Chemistry & Biology. 9: 17-23. PMID 11841935 DOI: 10.1016/S1074-5521(02)00087-X |
0.374 |
|
2001 |
Ye HF, O'Reilly KE, Koh JT. A subtype-selective thyromimetic designed to bind a mutant thyroid hormone receptor implicated in resistance to thyroid hormone. Journal of the American Chemical Society. 123: 1521-2. PMID 11456736 |
0.58 |
|
2001 |
Shi Y, Koh JT. Selective regulation of gene expression by an orthogonal estrogen receptor-ligand pair created by polar-group exchange. Chemistry & Biology. 8: 501-10. PMID 11358696 DOI: 10.1016/S1074-5521(01)00028-X |
0.654 |
|
2000 |
Xu W, Springfield SA, Koh JT. Highly efficient synthesis of 1-thioglycosides in solution and solid phase using iminophosphorane bases. Carbohydrate Research. 325: 169-76. PMID 10795807 DOI: 10.1016/S0008-6215(99)00327-4 |
0.707 |
|
1999 |
Koh JT, Putnam M, Tomic-Canic M, McDaniel CM. Selective regulation of gene expression using rationally-modified retinoic acid receptors [16] Journal of the American Chemical Society. 121: 1984-1985. DOI: 10.1021/Ja983988U |
0.672 |
|
1997 |
Koh JT, Cornish VW, Schultz PG. An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis. Biochemistry. 36: 11314-22. PMID 9298950 DOI: 10.1021/Bi9707685 |
0.598 |
|
1996 |
Norman TC, Gray NS, Koh JT, Schultz PG. A Structure-Based Library Approach to Kinase Inhibitors Journal of the American Chemical Society. 118: 7430-7431. DOI: 10.1021/Ja9614934 |
0.659 |
|
1994 |
Koh JT, Delaude L, Breslow R. Geometric Control of a Pyridoxal-Catalyzed Aldol Condensation Journal of the American Chemical Society. 116: 11234-11240. DOI: 10.1021/Ja00104A004 |
0.435 |
|
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