john j. mullins - Publications

Affiliations: 
Centre for Cardiovascular Science University of Edinburgh, Edinburgh, Scotland, United Kingdom 

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jones NK, Stewart K, Czopek A, Menzies RI, Thomson A, Moran CM, Cairns C, Conway BR, Denby L, Livingstone DEW, Wiseman J, Hadoke PW, Webb DJ, Dhaun N, Dear JW, ... Mullins JJ, et al. Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11914. PMID 32200679 DOI: 10.1161/Hypertensionaha.119.14308  0.37
2020 Ward M, Assmus AM, Mullins LJ, Peter A, Mansley MK, Bradley M, Mullins J. Cell Plasticity in the Kidney Collecting Duct of Hsd11b2 KO Mice and Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08650  0.362
2020 Mullins LJ, Ivy J, Rakova N, Mueller D, Mullins J. Skin and Kidney Contribute to Salt‐Sensitive Hypertension in the SAME rat The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06478  0.339
2019 Lerman LO, Kurtz TW, Touyz RM, Ellison DH, Chade AR, Crowley SD, Mattson DL, Mullins JJ, Osborn J, Eirin A, Reckelhoff JF, Iadecola C, Coffman TM. Animal Models of Hypertension: A Scientific Statement From the American Heart Association. Hypertension (Dallas, Tex. : 1979). HYP0000000000000090. PMID 30866654 DOI: 10.1161/Hyp.0000000000000090  0.34
2018 Shaw I, Rider S, Mullins J, Hughes J, Péault B. Pericytes in the renal vasculature: roles in health and disease. Nature Reviews. Nephrology. PMID 29942044 DOI: 10.1038/S41581-018-0032-4  0.338
2017 Buckley C, Nelson RJ, Mullins LJ, Sharp MG, Fleming S, Kenyon CJ, Semprini S, Steppan D, Peti-Peterdi J, Kurtz A, Christian H, Mullins JJ. Phenotypic dissection of the mouse Ren-1(d) knockout by complementation with human renin. The Journal of Biological Chemistry. PMID 29123029 DOI: 10.1074/Jbc.Ra117.000160  0.362
2017 Menzies RI, Zhao X, Mullins LJ, Mullins JJ, Cairns C, Wrobel N, Dunbar DR, Bailey MA, Kenyon CJ. Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses. Endocrine Connections. PMID 28720595 DOI: 10.1530/Ec-17-0092  0.328
2017 Rider SA, Christian HC, Mullins LJ, Howarth AR, MacRae CA, Mullins JJ. Zebrafish mesonephric renin cells are functionally conserved and comprise of two distinct morphological populations. American Journal of Physiology. Renal Physiology. ajprenal.00608.2016. PMID 28179256 DOI: 10.1152/Ajprenal.00608.2016  0.38
2017 Buckley C, Dun AR, Peter A, Bellamy C, Gross KW, Duncan RR, Mullins JJ. Bimodal dynamics of granular organelles in primary renin-expressing cells revealed using TIRF microscopy. American Journal of Physiology. Renal Physiology. 312: F200-F209. PMID 28069661 DOI: 10.1152/Ajprenal.00384.2016  0.335
2016 Mullins LJ, Conway BR, Menzies RI, Denby L, Mullins JJ. Renal disease pathophysiology and treatment: contributions from the rat. Disease Models & Mechanisms. 9: 1419-1433. PMID 27935823 DOI: 10.1242/Dmm.027276  0.356
2016 Stefanska A, Kenyon C, Christian HC, Buckley C, Shaw I, Mullins JJ, Péault B. Human kidney pericytes produce renin. Kidney International. PMID 27678158 DOI: 10.1016/J.Kint.2016.07.035  0.321
2016 Evans LC, Ivy JR, Wyrwoll C, McNairn JA, Menzies RI, Christensen TH, Al-Dujaili EA, Kenyon CJ, Mullins JJ, Seckl JR, Holmes MC, Bailey MA. Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension. Circulation. PMID 26951843 DOI: 10.1161/Circulationaha.115.019341  0.377
2016 Featherstone K, Hey K, Momiji H, McNamara AV, Patist AL, Woodburn J, Spiller DG, Christian HC, McNeilly AS, Mullins JJ, Finkenstädt BF, Rand DA, White MR, Davis JR. Spatially coordinated dynamic gene transcription in living pituitary tissue. Elife. 5. PMID 26828110 DOI: 10.7554/Elife.08494  0.326
2015 McNamara AV, Adamson AD, Dunham LS, Semprini S, Spiller DG, McNeilly AS, Mullins JJ, Davis JR, White MR. Role of estrogen response element in the human prolactin gene: transcriptional response and timing. Molecular Endocrinology (Baltimore, Md.). me20151186. PMID 26691151 DOI: 10.1210/Me.2015-1186  0.303
2015 Rider SA, Mullins LJ, Verdon RF, MacRae CA, Mullins JJ. Renin expression in developing zebrafish is associated with angiogenesis and requires the Notch pathway and endothelium. American Journal of Physiology. Renal Physiology. 309: F531-9. PMID 26202224 DOI: 10.1152/Ajprenal.00247.2015  0.37
2015 Menzies RI, Howarth AR, Unwin RJ, Tam FW, Mullins JJ, Bailey MA. Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats. Kidney International. PMID 26108066 DOI: 10.1038/Ki.2015.182  0.385
2015 Mullins LJ, Kenyon CJ, Bailey MA, Conway BR, Diaz ME, Mullins JJ. Mineralocorticoid Excess or Glucocorticoid Insufficiency: Renal and Metabolic Phenotypes in a Rat Hsd11b2 Knockout Model. Hypertension. PMID 26077568 DOI: 10.1161/Hypertensionaha.115.05262  0.353
2015 Holland PR, Pannozzo MA, Bastin ME, McNeilly AD, Ferguson KJ, Caughey S, Jansen MA, Merrifield GD, Marshall I, Mullins JJ, Wardlaw JM, Sutherland C, Horsburgh K. Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 188-92. PMID 25407269 DOI: 10.1038/Jcbfm.2014.201  0.313
2015 Hunter RW, Ivy JR, Flatman PW, Kenyon CJ, Craigie E, Mullins LJ, Bailey MA, Mullins JJ. Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model. Journal of the American Society of Nephrology : Jasn. 26: 1537-48. PMID 25349206 DOI: 10.1681/Asn.2013060634  0.349
2014 Conway BR, Betz B, Sheldrake TA, Manning JR, Dunbar DR, Dobyns A, Hughes J, Mullins JJ. Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis. Nephrology (Carlton, Vic.). 19: 802-13. PMID 25196678 DOI: 10.1111/Nep.12335  0.347
2014 Heijnen BF, Pelkmans LP, Danser AH, Garrelds IM, Mullins JJ, De Mey JG, Struijker-Boudier HA, Janssen BJ. Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 15: 69-81. PMID 23462119 DOI: 10.1177/1470320313480537  0.352
2013 Menzies RI, Unwin RJ, Dash RK, Beard DA, Cowley AW, Carlson BE, Mullins JJ, Bailey MA. Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats. Frontiers in Physiology. 4: 305. PMID 24187541 DOI: 10.3389/Fphys.2013.00305  0.396
2013 Wilson KS, Matrone G, Livingstone DE, Al-Dujaili EA, Mullins JJ, Tucker CS, Hadoke PW, Kenyon CJ, Denvir MA. Physiological roles of glucocorticoids during early embryonic development of the zebrafish (Danio rerio). The Journal of Physiology. 591: 6209-20. PMID 24167225 DOI: 10.1113/Jphysiol.2013.256826  0.303
2013 Pannozzo MA, Holland PR, Scullion G, Talbot R, Mullins JJ, Horsburgh K. Controlled hypertension induces cerebrovascular and gene alterations in Cyp1a1-Ren2 transgenic rats. Journal of the American Society of Hypertension : Jash. 7: 411-9. PMID 24119481 DOI: 10.1016/J.Jash.2013.07.011  0.39
2013 Heijnen BF, Nelissen J, van Essen H, Fazzi GE, Cohen Tervaert JW, Peutz-Kootstra CJ, Mullins JJ, Schalkwijk CG, Janssen BJ, Struijker-Boudier HA. Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response. Plos One. 8: e57815. PMID 23469072 DOI: 10.1371/Journal.Pone.0057815  0.396
2013 Wilson KS, Matrone G, Tucker CS, Mullins JJ, Kenyon CJ, Hadoke PWF, Denvir MA. Glucocorticoids play a key role in maturation and structural organisation of the developing zebrafish cardiovascular system European Heart Journal. 34: P1444-P1444. DOI: 10.1093/Eurheartj/Eht308.P1444  0.307
2012 Craigie E, Evans LC, Mullins JJ, Bailey MA. Failure to downregulate the epithelial sodium channel causes salt sensitivity in Hsd11b2 heterozygote mice. Hypertension. 60: 684-90. PMID 22777941 DOI: 10.1161/Hypertensionaha.112.196410  0.356
2012 Evans LC, Livingstone DE, Kenyon CJ, Jansen MA, Dear JW, Mullins JJ, Bailey MA. A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice. American Journal of Physiology. Renal Physiology. 303: F494-502. PMID 22622456 DOI: 10.1152/Ajprenal.00165.2012  0.345
2012 Ashek A, Menzies RI, Mullins LJ, Bellamy CO, Harmar AJ, Kenyon CJ, Flatman PW, Mullins JJ, Bailey MA. Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat. Plos One. 7: e36311. PMID 22558431 DOI: 10.1371/Journal.Pone.0036311  0.387
2012 Peters BS, Dornaika R, Hosten N, Hadlich S, Mullins JJ, Peters J, Rettig R. Regression of cardiac hypertrophy in cyp1a1ren-2 transgenic rats. Journal of Magnetic Resonance Imaging : Jmri. 36: 373-8. PMID 22517449 DOI: 10.1002/Jmri.23661  0.336
2012 Semprini S, McNamara AV, Awais R, Featherstone K, Harper CV, McNeilly JR, Patist A, Rossi AG, Dransfield I, McNeilly AS, Davis JR, White MR, Mullins JJ. Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model. Endocrinology. 153: 2724-34. PMID 22495675 DOI: 10.1210/En.2011-1926  0.361
2012 Rider SA, Tucker CS, del-Pozo J, Rose KN, MacRae CA, Bailey MA, Mullins JJ. Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. The Journal of Physiology. 590: 1803-9. PMID 22331420 DOI: 10.1113/Jphysiol.2011.224352  0.304
2012 Conway BR, Rennie J, Bailey MA, Dunbar DR, Manning JR, Bellamy CO, Hughes J, Mullins JJ. Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 23: 405-11. PMID 22193383 DOI: 10.1681/Asn.2011060577  0.32
2012 Liskovykh MA, Chuykin IA, Ranjan A, Safina DA, Tolkunova EN, Minina YM, Zhdanova NS, Dyban PA, Mullins JJ, Kostyleva EI, Chikhirzhina EV, Bader M, Alenina N, Tomilin AN. Generation of rat-induced pluripotent stem cells: Reprogramming and culture medium Cell and Tissue Biology. 6: 115-121. DOI: 10.1134/S1990519X12020095  0.348
2011 Chang SP, Mullins JJ, Morley SD, West JD. Transition from organogenesis to stem cell maintenance in the mouse adrenal cortex. Organogenesis. 7: 267-80. PMID 22198434 DOI: 10.4161/Org.7.4.18060  0.301
2011 Liskovykh M, Chuykin I, Ranjan A, Safina D, Popova E, Tolkunova E, Mosienko V, Minina JM, Zhdanova NS, Mullins JJ, Bader M, Alenina N, Tomilin A. Derivation, characterization, and stable transfection of induced pluripotent stem cells from Fischer344 rats. Plos One. 6: e27345. PMID 22076153 DOI: 10.1371/Journal.Pone.0027345  0.353
2011 Heijnen BF, Peutz-Kootstra CJ, Mullins JJ, Janssen BJ, Struijker-Boudier HA. Transient renin-angiotensin system stimulation in an early stage of life causes sustained hypertension in rats. Journal of Hypertension. 29: 2369-80. PMID 22025236 DOI: 10.1097/Hjh.0B013E32834Cfcf4  0.368
2011 Featherstone K, Harper CV, McNamara A, Semprini S, Spiller DG, McNeilly J, McNeilly AS, Mullins JJ, White MR, Davis JR. Pulsatile patterns of pituitary hormone gene expression change during development. Journal of Cell Science. 124: 3484-91. PMID 21984812 DOI: 10.1242/Jcs.088500  0.341
2011 Chebotareva T, Taylor J, Mullins JJ, Wilmut I. Rat eggs cannot wait: Spontaneous exit from meiotic metaphase-II arrest. Molecular Reproduction and Development. 78: 795-807. PMID 21910153 DOI: 10.1002/Mrd.21385  0.31
2011 Howard CG, Mullins JJ, Mitchell KD. Direct renin inhibition with aliskiren normalizes blood pressure in Cyp1a1-Ren2 transgenic rats with inducible angiotensin ii-dependent malignant hypertension. The American Journal of the Medical Sciences. 341: 383-7. PMID 21358304 DOI: 10.1097/Maj.0B013E31820Fa8Da  0.413
2011 Bailey MA, Craigie E, Livingstone DE, Kotelevtsev YV, Al-Dujaili EA, Kenyon CJ, Mullins JJ. Hsd11b2 haploinsufficiency in mice causes salt sensitivity of blood pressure. Hypertension. 57: 515-20. PMID 21282561 DOI: 10.1161/Hypertensionaha.110.163782  0.34
2011 Deuchar GA, McLean D, Hadoke PW, Brownstein DG, Webb DJ, Mullins JJ, Chapman K, Seckl JR, Kotelevtsev YV. 11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. Endocrinology. 152: 236-46. PMID 21106873 DOI: 10.1210/En.2010-0925  0.319
2011 Prieto MC, Williams DE, Liu L, Kavanagh KL, Mullins JJ, Mitchell KD. Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension. American Journal of Physiology. Renal Physiology. 300: F581-8. PMID 21068087 DOI: 10.1152/Ajprenal.00433.2010  0.427
2010 Meek S, Buehr M, Sutherland L, Thomson A, Mullins JJ, Smith AJ, Burdon T. Efficient gene targeting by homologous recombination in rat embryonic stem cells. Plos One. 5: e14225. PMID 21151976 DOI: 10.1371/Journal.Pone.0014225  0.351
2010 Milani CJ, Kobori H, Mullins JJ, Mitchell KD. Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. The American Journal of the Medical Sciences. 340: 389-94. PMID 20724906 DOI: 10.1097/Maj.0B013E3181Eabd28  0.323
2010 Manning JR, Bailey MA, Soares DC, Dunbar DR, Mullins JJ. In silico structure-function analysis of pathological variation in the HSD11B2 gene sequence. Physiological Genomics. 42: 319-30. PMID 20571110 DOI: 10.1152/Physiolgenomics.00053.2010  0.315
2010 Campbell DJ, Karam H, Bruneval P, Mullins JJ, Ménard J. Increased dietary NaCl potentiates the effects of elevated prorenin levels on blood pressure and organ disease. Journal of Hypertension. 28: 1429-37. PMID 20453664 DOI: 10.1097/Hjh.0B013E3283391F13  0.382
2010 Howard CG, Mullins JJ, Mitchell KD. Transient induction of ANG II-dependent malignant hypertension causes sustained elevation of blood pressure and augmentation of the pressor response to ANG II in CYP1A1-REN2 transgenic rats. The American Journal of the Medical Sciences. 339: 543-8. PMID 20375689 DOI: 10.1097/Maj.0B013E3181D82A62  0.364
2010 Williams DE, Prieto MC, Mullins JJ, Navar LG, Mitchell KD. AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet. The American Journal of the Medical Sciences. 339: 356-61. PMID 20224314 DOI: 10.1097/Maj.0B013E3181D2B0A8  0.376
2010 Harper CV, Featherstone K, Semprini S, Friedrichsen S, McNeilly J, Paszek P, Spiller DG, McNeilly AS, Mullins JJ, Davis JR, White MR. Dynamic organisation of prolactin gene expression in living pituitary tissue. Journal of Cell Science. 123: 424-30. PMID 20130141 DOI: 10.1242/Jcs.060434  0.348
2010 Husková Z, Vanourková Z, Erbanová M, Thumová M, Opocenský M, Mullins JJ, Kramer HJ, Bürgelová M, Cervenka L. Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats. Journal of Hypertension. 28: 495-509. PMID 19927008 DOI: 10.1097/Hjh.0B013E3283345D69  0.369
2010 Dunbar DR, Khaled H, Evans LC, Al-Dujaili EA, Mullins LJ, Mullins JJ, Kenyon CJ, Bailey MA. Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney. Physiological Genomics. 40: 158-66. PMID 19920212 DOI: 10.1152/Physiolgenomics.00088.2009  0.384
2010 Peters BS, Kuttler B, Beineke A, Lorenz G, Thiele A, Nicolai O, Rettig R, Mullins JJ, Peters J. The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats. Journal of Cellular and Molecular Medicine. 14: 1318-27. PMID 19432815 DOI: 10.1111/J.1582-4934.2009.00778.X  0.358
2009 Campbell DJ, Karam H, Ménard J, Bruneval P, Mullins JJ. Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver. Hypertension. 54: 1248-53. PMID 19841286 DOI: 10.1161/Hypertensionaha.109.138495  0.391
2009 Bailey MA, Mullins JJ, Kenyon CJ. Mineralocorticoid and glucocorticoid receptors stimulate epithelial sodium channel activity in a mouse model of Cushing syndrome. Hypertension. 54: 890-6. PMID 19635986 DOI: 10.1161/Hypertensionaha.109.134973  0.359
2009 Carter RN, Paterson JM, Tworowska U, Stenvers DJ, Mullins JJ, Seckl JR, Holmes MC. Hypothalamic-pituitary-adrenal axis abnormalities in response to deletion of 11beta-HSD1 is strain-dependent. Journal of Neuroendocrinology. 21: 879-87. PMID 19602102 DOI: 10.1111/J.1365-2826.2009.01899.X  0.314
2009 Erbanová M, Thumová M, Husková Z, Vanecková I, Vanourková Z, Mullins JJ, Kramer HJ, Bürgelová M, Rakusan D, Cervenka L. Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats. Journal of Hypertension. 27: 575-86. PMID 19330918 DOI: 10.1097/Hjh.0B013E32831Cbd5A  0.389
2009 Liu X, Bellamy CO, Bailey MA, Mullins LJ, Dunbar DR, Kenyon CJ, Brooker G, Kantachuvesiri S, Maratou K, Ashek A, Clark AF, Fleming S, Mullins JJ. Angiotensin-converting enzyme is a modifier of hypertensive end organ damage. The Journal of Biological Chemistry. 284: 15564-72. PMID 19307186 DOI: 10.1074/Jbc.M806584200  0.375
2009 Semprini S, Friedrichsen S, Harper CV, McNeilly JR, Adamson AD, Spiller DG, Kotelevtseva N, Brooker G, Brownstein DG, McNeilly AS, White MR, Davis JR, Mullins JJ. Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model. Molecular Endocrinology (Baltimore, Md.). 23: 529-38. PMID 19147700 DOI: 10.1210/Me.2008-0399  0.384
2009 Mullins LJ, Peter A, Wrobel N, McNeilly JR, McNeilly AS, Al-Dujaili EA, Brownstein DG, Mullins JJ, Kenyon CJ. Cyp11b1 null mouse, a model of congenital adrenal hyperplasia. The Journal of Biological Chemistry. 284: 3925-34. PMID 19029289 DOI: 10.1074/Jbc.M805081200  0.352
2009 Chebotareva T, Mullins J, Wilmut I. 234 MECHANISMS OF SPONTANEOUS ACTIVATION IN RAT OOCYTES Reproduction, Fertility and Development. 21: 215. DOI: 10.1071/Rdv21N1Ab234  0.308
2008 Aitman TJ, Critser JK, Cuppen E, Dominiczak A, Fernandez-Suarez XM, Flint J, Gauguier D, Geurts AM, Gould M, Harris PC, Holmdahl R, Hubner N, Izsvák Z, Jacob HJ, Kuramoto T, ... ... Mullins J, et al. Progress and prospects in rat genetics: a community view. Nature Genetics. 40: 516-22. PMID 18443588 DOI: 10.1038/Ng.147  0.343
2008 Peters B, Grisk O, Becher B, Wanka H, Kuttler B, Lüdemann J, Lorenz G, Rettig R, Mullins JJ, Peters J. Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. Journal of Hypertension. 26: 102-9. PMID 18090546 DOI: 10.1097/Hjh.0B013E3282F0Ab66  0.359
2008 Bailey MA, Paterson JM, Hadoke PW, Wrobel N, Bellamy CO, Brownstein DG, Seckl JR, Mullins JJ. A switch in the mechanism of hypertension in the syndrome of apparent mineralocorticoid excess. Journal of the American Society of Nephrology : Jasn. 19: 47-58. PMID 18032795 DOI: 10.1681/Asn.2007040401  0.386
2008 Adamson AD, Friedrichsen S, Semprini S, Harper CV, Mullins JJ, White MR, Davis JR. Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling. Endocrinology. 149: 687-94. PMID 18006630 DOI: 10.1210/En.2007-1066  0.313
2008 Patterson ME, Mullins JJ, Mitchell KD. Renoprotective effects of neuronal NOS-derived nitric oxide and cyclooxygenase-2 metabolites in transgenic rats with inducible malignant hypertension. American Journal of Physiology. Renal Physiology. 294: F205-11. PMID 17977909 DOI: 10.1152/Ajprenal.00150.2007  0.331
2007 Ortiz RM, Graciano ML, Mullins JJ, Mitchell KD. Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats American Journal of Physiology - Renal Physiology. 293. PMID 17715265 DOI: 10.1152/Ajprenal.00124.2007  0.321
2007 Graciano ML, Mouton CR, Patterson ME, Seth DM, Mullins JJ, Mitchell KD. Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. American Journal of Physiology. Renal Physiology. 292: F1858-66. PMID 17344186 DOI: 10.1152/Ajprenal.00469.2006  0.404
2006 Mitchell KD, Bagatell SJ, Miller CS, Mouton CR, Seth DM, Mullins JJ. Genetic clamping of renin gene expression induces hypertension and elevation of intrarenal Ang II levels of graded severity in Cyp1a1-Ren2 transgenic rats. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 7: 74-86. PMID 17083061 DOI: 10.3317/Jraas.2006.013  0.411
2006 Vanourková Z, Kramer HJ, Husková Z, Vanecková I, Opocenský M, Chábová VC, Tesar V, Skaroupková P, Thumová M, Dohnalová M, Mullins JJ, Cervenka L. AT1 receptor blockade is superior to conventional triple therapy in protecting against end-organ damage in Cyp1a1-Ren-2 transgenic rats with inducible hypertension. Journal of Hypertension. 24: 2465-72. PMID 17082731 DOI: 10.1097/01.Hjh.0000251909.00923.22  0.398
2006 Barton M, Mullins JJ, Bailey MA, Kretzler M. Role of endothelin receptors for renal protection and survival in hypertension: waiting for clinical trials. Hypertension. 48: 834-7. PMID 17015776 DOI: 10.1161/01.Hyp.0000245138.09687.8A  0.395
2006 Mullins JJ, Mullins LJ, Dunbar DR, Brammar WJ, Gross KW, Morley SD. Identification of a human ortholog of the mouse Dcpp gene locus, encoding a novel member of the CSP-1/Dcpp salivary protein family. Physiological Genomics. 28: 129-40. PMID 16954406 DOI: 10.1152/Physiolgenomics.00153.2006  0.603
2006 Gilmour JS, Coutinho AE, Cailhier JF, Man TY, Clay M, Thomas G, Harris HJ, Mullins JJ, Seckl JR, Savill JS, Chapman KE. Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes. Journal of Immunology (Baltimore, Md. : 1950). 176: 7605-11. PMID 16751407 DOI: 10.4049/Jimmunol.176.12.7605  0.301
2006 Opay AL, Mouton CR, Mullins JJ, Mitchell KD. Cyclooxygenase-2 inhibition normalizes arterial blood pressure in CYP1A1-REN2 transgenic rats with inducible ANG II-dependent malignant hypertension American Journal of Physiology - Renal Physiology. 291. PMID 16622181 DOI: 10.1152/Ajprenal.00032.2006  0.366
2006 Mullins LJ, Bailey MA, Mullins JJ. Hypertension, kidney, and transgenics: a fresh perspective. Physiological Reviews. 86: 709-46. PMID 16601272 DOI: 10.1152/Physrev.00016.2005  0.391
2006 Heerkens EH, Shaw L, Ryding A, Brooker G, Mullins JJ, Austin C, Ohanian V, Heagerty AM. alphaV integrins are necessary for eutrophic inward remodeling of small arteries in hypertension. Hypertension (Dallas, Tex. : 1979). 47: 281-7. PMID 16380536 DOI: 10.1161/01.Hyp.0000198428.45132.02  0.356
2006 Friedrichsen S, Harper CV, Semprini S, Wilding M, Adamson AD, Spiller DG, Nelson G, Mullins JJ, White MR, Davis JR. Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling. Endocrinology. 147: 773-81. PMID 16254029 DOI: 10.1210/En.2005-0967  0.304
2005 Ye P, Kenyon CJ, MacKenzie SM, Jong AS, Miller C, Gray GA, Wallace A, Ryding AS, Mullins JJ, McBride MW, Graham D, Fraser R, Connell JM, Davies E. The aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) genes are not expressed in the rat heart. Endocrinology. 146: 5287-93. PMID 16179417 DOI: 10.1210/En.2005-0370  0.376
2005 Paterson JM, Seckl JR, Mullins JJ. Genetic manipulation of 11beta-hydroxysteroid dehydrogenases in mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R642-52. PMID 16105819 DOI: 10.1152/Ajpregu.00017.2005  0.309
2005 Mitchell KD, Mullins JJ. Enhanced tubuloglomerular feedback in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. American Journal of Physiology. Renal Physiology. 289: F1210-6. PMID 16033920 DOI: 10.1152/Ajprenal.00461.2004  0.38
2005 Patterson ME, Mouton CR, Mullins JJ, Mitchell KD. Interactive effects of superoxide anion and nitric oxide on blood pressure and renal hemodynamics in transgenic rats with inducible malignant hypertension. American Journal of Physiology. Renal Physiology. 289: F754-9. PMID 15900020 DOI: 10.1152/Ajprenal.00419.2004  0.367
2005 Howard LL, Patterson ME, Mullins JJ, Mitchell KD. Salt-sensitive hypertension develops after transient induction of ANG II-dependent hypertension in Cyp1a1-Ren2 transgenic rats. American Journal of Physiology. Renal Physiology. 288: F810-5. PMID 15585671 DOI: 10.1152/Ajprenal.00148.2004  0.363
2005 Patterson ME, Mouton CR, Mullins JJ, Mitchell KD. 428 INTERACTIVE EFFECTS OF NEURONAL NITRIC OXIDE SYNTHASE AND CYCLOOXYGENASE-2 ON RENAL HEMODYNAMICS IN CYP1A1-REN2 TRANSGENIC RATS WITH MALIGNANT HYPERTENSION Journal of Investigative Medicine. 53: S329.3-S329. DOI: 10.2310/6650.2005.00006.427  0.378
2005 Opay AL, Mullins JJ, Mitchell KD. 207 BLOOD PRESSURE AND RENAL FUNCTIONAL RESPONSES TO COX-1 AND COX-2 INHIBITION IN CYP1A1-REN2 RATS WITH INDUCIBLE MALIGNANT HYPERTENSION Journal of Investigative Medicine. 53: S289.2-S289. DOI: 10.2310/6650.2005.00006.206  0.396
2005 Kelly PAT, Ferrington L, Mullins JJ. Altered cerebrovascular control in response to hypertension in a novel transgenic rat model of malignant hypertension Journal of Cerebral Blood Flow and Metabolism. 25. DOI: 10.1038/Sj.Jcbfm.9591524.0536  0.378
2004 Pall GS, Wallis J, Axton R, Brownstein DG, Gautier P, Buerger K, Mulford C, Mullins JJ, Forrester LM. A novel transmembrane MSP-containing protein that plays a role in right ventricle development. Genomics. 84: 1051-9. PMID 15533722 DOI: 10.1016/J.Ygeno.2004.08.017  0.316
2004 Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR, Mullins JJ. Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 7088-93. PMID 15118095 DOI: 10.1073/Pnas.0305524101  0.313
2004 Mullins LJ, Mullins JJ. Large transgenes reveal their secrets. Focus on "differential expression of the closely linked KISS1, REN, and FLJ10761 genes in transgenic mice". Physiological Genomics. 17: 1-3. PMID 15020719 DOI: 10.1152/Physiolgenomics.00019.2004  0.313
2004 Collidge TA, Lammie GA, Fleming S, Mullins JJ. The role of the renin-angiotensin system in malignant vascular injury affecting the systemic and cerebral circulations. Progress in Biophysics and Molecular Biology. 84: 301-19. PMID 14769441 DOI: 10.1016/J.Pbiomolbio.2003.11.003  0.369
2003 Holmes MC, Yau JL, Kotelevtsev Y, Mullins JJ, Seckl JR. 11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles. Annals of the New York Academy of Sciences. 1007: 357-66. PMID 14993069 DOI: 10.1196/Annals.1286.035  0.307
2003 Christy C, Hadoke PW, Paterson JM, Mullins JJ, Seckl JR, Walker BR. 11beta-hydroxysteroid dehydrogenase type 2 in mouse aorta: localization and influence on response to glucocorticoids. Hypertension (Dallas, Tex. : 1979). 42: 580-7. PMID 12925564 DOI: 10.1161/01.Hyp.0000088855.06598.5B  0.335
2003 Patek CE, Fleming S, Miles CG, Bellamy CO, Ladomery M, Spraggon L, Mullins J, Hastie ND, Hooper ML. Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis. Human Molecular Genetics. 12: 2379-94. PMID 12915483 DOI: 10.1093/Hmg/Ddg240  0.351
2003 Masuzaki H, Yamamoto H, Kenyon CJ, Elmquist JK, Morton NM, Paterson JM, Shinyama H, Sharp MG, Fleming S, Mullins JJ, Seckl JR, Flier JS. Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. The Journal of Clinical Investigation. 112: 83-90. PMID 12840062 DOI: 10.1172/Jci17845  0.352
2003 Pybus R, Barnard E, Estibeiro P, Mullins J, MacLeod N. Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related. Neurobiology of Disease. 12: 212-24. PMID 12742741 DOI: 10.1016/S0969-9961(03)00016-0  0.307
2003 Mullins LJ, Mullins J. Current successes and limitations of using genetic modification for blood pressure research. Pflugers Archiv : European Journal of Physiology. 445: 491-4. PMID 12548394 DOI: 10.1007/S00424-002-0968-9  0.391
2003 Buehr M, Nichols J, Stenhouse F, Mountford P, Greenhalgh CJ, Kantachuvesiri S, Brooker G, Mullins J, Smith AG. Rapid loss of Oct-4 and pluripotency in cultured rodent blastocysts and derivative cell lines. Biology of Reproduction. 68: 222-9. PMID 12493717 DOI: 10.1095/Biolreprod.102.006197  0.316
2002 Peters J, Farrenkopf R, Clausmeyer S, Zimmer J, Kantachuvesiri S, Sharp MG, Mullins JJ. Functional significance of prorenin internalization in the rat heart. Circulation Research. 90: 1135-41. PMID 12039805 DOI: 10.1161/01.Res.0000019242.51541.99  0.361
2002 Mullins LJ, Brooker G, Mullins JJ. Transgenesis in the rat. Methods in Molecular Biology (Clifton, N.J.). 180: 255-70. PMID 11873653 DOI: 10.1385/1-59259-178-7:255  0.303
2001 Hadoke PW, Christy C, Kotelevtsev YV, Williams BC, Kenyon CJ, Seckl JR, Mullins JJ, Walker BR. Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11beta-hydroxysteroid dehydrogenase. Circulation. 104: 2832-7. PMID 11733403 DOI: 10.1161/Hc4801.100077  0.304
2001 Ryding ADS, Sharp MGF, Mullins JJ. Conditional transgenic technologies. Journal of Endocrinology. 171: 1-14. PMID 11572785 DOI: 10.1677/Joe.0.1710001  0.315
2001 Kantachuvesiri S, Fleming S, Peters J, Peters B, Brooker G, Lammie AG, McGrath I, Kotelevtsev Y, Mullins JJ. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease. Journal of Biological Chemistry. 276: 36727-36733. PMID 11448960 DOI: 10.1074/Jbc.M103296200  0.355
2001 Yau JL, Noble J, Kenyon CJ, Hibberd C, Kotelevtsev Y, Mullins JJ, Seckl JR. Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proceedings of the National Academy of Sciences of the United States of America. 98: 4716-21. PMID 11274359 DOI: 10.1073/Pnas.071562698  0.3
2001 Holmes MC, Kotelevtsev Y, Mullins JJ, Seckl JR. Phenotypic analysis of mice bearing targeted deletions of 11beta-hydroxysteroid dehydrogenases 1 and 2 genes. Molecular and Cellular Endocrinology. 171: 15-20. PMID 11165006 DOI: 10.1016/S0303-7207(00)00386-5  0.311
2000 Mullins LJ, Payne CM, Kotelevtseva N, Brooker G, Fleming S, Harris S, Mullins JJ. Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus. The Journal of Biological Chemistry. 275: 40378-84. PMID 10995772 DOI: 10.1074/Jbc.M007315200  0.355
1999 Payne CM, Mullins LJ, Mullins JJ. Manipulating large genomic clones via in vivo recombination in bacteria. Journal of Human Hypertension. 13: 845-8. PMID 10618675 DOI: 10.1038/Sj.Jhh.1000921  0.343
1999 Kantachuvesiri S, Haley CS, Fleming S, Kurian K, Whitworth CE, Wenham P, Kotelevtsev Y, Mullins JJ. Genetic mapping of modifier loci affecting malignant hypertension in TGRmRen2 rats. Kidney International. 56: 414-20. PMID 10432379 DOI: 10.1046/J.1523-1755.1999.00571.X  0.325
1999 Brosnan MJ, Devlin AM, Clark JS, Mullins JJ, Dominiczak AF. Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27. American Journal of Hypertension. 12: 724-31. PMID 10411370 DOI: 10.1016/S0895-7061(99)00021-7  0.363
1999 Kotelevtsev Y, Brown RW, Fleming S, Kenyon C, Edwards CR, Seckl JR, Mullins JJ. Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2. The Journal of Clinical Investigation. 103: 683-9. PMID 10074485 DOI: 10.1172/Jci4445  0.349
1999 Jacinto SM, Mullins JJ, Mitchell KD. Enhanced renal vascular responsiveness to angiotensin II in hypertensive ren-2 transgenic rats American Journal of Physiology - Renal Physiology. 276. PMID 9950963 DOI: 10.1152/Ajprenal.1999.276.2.F315  0.32
1999 Montgomery HE, Kiernan LA, Whitworth CE, Fleming S, Unger T, Gohlke P, Mullins JJ, McEwan JR. Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27. Journal of Hypertension. 16: 635-43. PMID 9797175 DOI: 10.1097/00004872-199816050-00011  0.342
1998 McClive P, Pall G, Newton K, Lee M, Mullins J, Forrester L. Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 212: 267-76. PMID 9626501 DOI: 10.1002/(Sici)1097-0177(199806)212:2<267::Aid-Aja11>3.0.Co;2-1  0.335
1998 Flynn P, Lawn R, Mullins J, Weissberg P. Transgenic Rats Expressing Human Apolipoprotein(a) Clinical Science. 94: 7P-7P. DOI: 10.1042/Cs094007Pa  0.344
1997 Kotelevtsev Y, Holmes MC, Burchell A, Houston PM, Schmoll D, Jamieson P, Best R, Brown R, Edwards CR, Seckl JR, Mullins JJ. 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proceedings of the National Academy of Sciences of the United States of America. 94: 14924-9. PMID 9405715 DOI: 10.1073/Pnas.94.26.14924  0.312
1997 Clark AF, Sharp MGF, Morley SD, Fleming S, Peters J, Mullins JJ. Renin-1 Is Essential for Normal Renal Juxtaglomerular Cell Granulation and Macula Densa Morphology Journal of Biological Chemistry. 272: 18185-18190. PMID 9218454 DOI: 10.1074/Jbc.272.29.18185  0.383
1996 McNeilly JR, Brown P, Mullins J, Clark AJ, McNeilly AS. Characterization of the ovine LHβ-subunit gene: the promoter is regulated by GnRH and gonadal steroids in transgenic mice Journal of Endocrinology. 151: 481-489. PMID 8994393 DOI: 10.1677/Joe.0.1510481  0.317
1996 Morley SD, Viard I, Parker KL, Mullins JJ. Adrenocortical-specific transgene expression directed by steroid hydroxylase gene promoters. Endocrine Research. 22: 631-9. PMID 8969922 DOI: 10.1080/07435809609043757  0.333
1996 Sharp MGF, Fettes D, Brooker G, Clark AF, Peters J, Fleming S, Mullins JJ. Targeted Inactivation of the Ren-2 Gene in Mice Hypertension. 28: 1126-1131. PMID 8952610 DOI: 10.1161/01.Hyp.28.6.1126  0.382
1996 Véniant M, Ménard J, Bruneval P, Morley S, Gonzales MF, Mullins J. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. The Journal of Clinical Investigation. 98: 1966-70. PMID 8903314 DOI: 10.1172/Jci119000  0.419
1996 Lantelme P, Lo M, Mullins JJ, Gharib C, Bizollon CA, Sassard J. Comparison between chronic converting enzyme inhibition and AT1 blockade in mRen2 transgenic rats. Journal of Cardiovascular Pharmacology. 27: 476-81. PMID 8847862 DOI: 10.1097/00005344-199604000-00004  0.364
1996 Plass C, Shibata H, Kalcheva I, Mullins L, Kotelevtseva N, Mullins J, Kato R, Sasaki H, Hirotsune S, Okazaki Y, Held WA, Hayashizaki Y, Chapman VM. Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nature Genetics. 14: 106-9. PMID 8782830 DOI: 10.1038/Ng0996-106  0.305
1996 Clark AF, Sharp MGF, Mullins JJ. Gene targeting and its application to basic hypertension research. Clinical Science. 90: 435-446. PMID 8697712 DOI: 10.1042/Cs0900435  0.3
1996 Mullins LJ, Mullins JJ. Transgenesis in the rat and larger mammals. The Journal of Clinical Investigation. 97: 1557-60. PMID 8601618 DOI: 10.1172/Jci118579  0.309
1996 Kotelevtsev Y, Jamieson P, Best R, Stewart F, Edwards CRW, Seckl J, Mullins J. Inactivation of 11β-Hydroxysteroid dehydrogenase type 1 by gene targeting in mice Endocrine Research. 22: 791-792. DOI: 10.1080/07435809609043777  0.308
1995 Véniant M, Whitworth CE, Ménard J, Sharp MG, Gonzales MF, Bruneval P, Mullins JJ. Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats. American Journal of Hypertension. 8: 1167-76. PMID 8998250 DOI: 10.1016/0895-7061(95)00254-5  0.374
1995 Gardiner SM, March JE, Kemp PA, Mullins JJ, Bennett T. Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen-2)27), hypertensive rats. British Journal of Pharmacology. 116: 2237-44. PMID 8564254 DOI: 10.1111/J.1476-5381.1995.Tb15059.X  0.389
1995 Rajan V, Chapman KE, Lyons V, Jamieson P, Mullins JJ, Edwards CR, Seckl JR. Cloning, sequencing and tissue-distribution of mouse 11 beta-hydroxysteroid dehydrogenase-1 cDNA. The Journal of Steroid Biochemistry and Molecular Biology. 52: 141-7. PMID 7873449 DOI: 10.1016/0960-0760(94)00159-J  0.307
1995 Mitchell KD, Mullins JJ. ANG II dependence of tubuloglomerular feedback responsiveness in hypertensive ren-2 transgenic rats American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268. PMID 7771510 DOI: 10.1152/Ajprenal.1995.268.5.F821  0.326
1995 Whitworth CE, Fleming S, Kotelevtsev Y, Manson L, Brooker GA, Cumming AD, Mullins JJ. A genetic model of malignant phase hypertension in rats. Kidney International. 47: 529-35. PMID 7723238 DOI: 10.1038/Ki.1995.66  0.348
1995 Morley SD, Viard I, Parker KL, Mullins JJ. Adrenal-specific transgene expression and derivation of conditionally immortal rat adrenocortical cell lines. Endocrine Research. 21: 353-7. PMID 7588398 DOI: 10.3109/07435809509030451  0.333
1995 Sharpe RM, Maguire SM, Saunders PT, Millar MR, Russell LD, Ganten D, Bachmann S, Mullins L, Mullins JJ. Infertility in a transgenic rat due to impairment of cytoplasmic elimination and sperm release from the Sertoli cells. Biology of Reproduction. 53: 214-26. PMID 7492673 DOI: 10.1095/Biolreprod53.2.214  0.372
1995 Whitworth CE, Veniant MM, Firth JD, Cumming AD, Mullins JJ. Endothelin in the kidney in malignant phase hypertension. Hypertension. 26: 925-31. PMID 7490150 DOI: 10.1161/01.Hyp.26.6.925  0.401
1994 Mullins JJ, Mullins LJ. Transgenes, hypotheses, and hypertension. Hypertension (Dallas, Tex. : 1979). 23: 428-30. PMID 8144211 DOI: 10.1161/01.Hyp.23.4.428  0.351
1994 Kock K, Morley SD, Mullins JJ, Schmale H. Denatonium bitter tasting among transgenic mice expressing rat von Ebner's gland protein Physiology & Behavior. 56: 1173-1177. PMID 7878087 DOI: 10.1016/0031-9384(94)90362-X  0.358
1994 Whitworth CE, Fleming S, Cumming AD, Morton JJ, Burns NJ, Williams BC, Mullins JJ. Spontaneous development of malignant phase hypertension in transgenic Ren-2 rats. Kidney International. 46: 1528-32. PMID 7699997 DOI: 10.1038/Ki.1994.437  0.37
1994 Mullins J, Ogg D, Barrett G, Peters J, Whitworth C. Redesigning transgenics — extrarenal expression of mouse ren-2 prorenin Regulatory Peptides. 53: 137. DOI: 10.1016/0167-0115(94)90616-5  0.312
1993 Peters J, Münter K, Bader M, Hackenthal E, Mullins JJ, Ganten D. Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II, and calcium. The Journal of Clinical Investigation. 91: 742-7. PMID 8383701 DOI: 10.1172/Jci116292  0.395
1993 Zhao Y, Bader M, Kreutz R, Fernandez-Alfonso M, Zimmermann F, Ganten U, Metzger R, Ganten D, Mullins JJ, Peters J. Ontogenetic regulation of mouse Ren-2d renin gene in transgenic hypertensive rats, TGR(mREN2)27. The American Journal of Physiology. 265: E699-707. PMID 8238495 DOI: 10.1152/ajpendo.1993.265.5.E699  0.327
1993 Barrett G, Mullins JJ. Transgenic animal models of cardiovascular disease. Current Opinion in Biotechnology. 3: 637-40. PMID 1369120 DOI: 10.1016/0958-1669(92)90008-7  0.351
1993 Lantelme P, Lo M, Mullins JJ, Sassard J. 111 Angiotensin II type 2 receptors are involved in urine concentration in transgenic (mRen-2) rats Journal of Hypertension. 11: S445. DOI: 10.1097/00004872-199312050-00279  0.319
1993 Linger T, Ganten D, Johnston CI, Lever AF, Mullins JJ, Sassard J, van Zwieten PA. Do transgenic techniques help us to understand hypertension? Journal of Hypertension. 11: S374???S379. DOI: 10.1097/00004872-199312050-00166  0.304
1992 Bachmann S, Peters J, Engler E, Ganten D, Mullins J. Transgenic rats carrying the mouse renin gene--morphological characterization of a low-renin hypertension model. Kidney International. 41: 24-36. PMID 1593860 DOI: 10.1038/Ki.1992.4  0.434
1992 Barrett GL, Mullins JJ. Strategies towards a transgenic model of essential hypertension. Biochemical Pharmacology. 43: 925-30. PMID 1532493 DOI: 10.1016/0006-2952(92)90594-9  0.388
1992 Sander M, Bader M, Djavidani B, Maser-Gluth C, Vecsei P, Mullins J, Ganten D, Peters J. The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27. Endocrinology. 131: 807-14. PMID 1322284 DOI: 10.1210/Endo.131.2.1322284  0.38
1992 Kimura S, Mullins JJ, Bunnemann B, Metzger R, Hilgenfeldt U, Zimmermann F, Jacob H, Fuxe K, Ganten D, Kaling M. High blood pressure in transgenic mice carrying the rat angiotensinogen gene. The Embo Journal. 11: 821-827. DOI: 10.1002/J.1460-2075.1992.Tb05119.X  0.419
1991 Ganten D, Lindpaintner K, Ganten U, Peters J, Zimmermann F, Bader M, Mullins J. Transgenic rats: new animal models in hypertension research. Invited lecture. Hypertension (Dallas, Tex. : 1979). 17: 843-55. PMID 2045167 DOI: 10.1161/01.Hyp.17.6.843  0.35
1991 Ganten D, Takahashi S, Lindpaintner K, Mullins J. Genetic basis of hypertension. The renin-angiotensin paradigm. Hypertension. 18. PMID 1937672 DOI: 10.1161/01.Hyp.18.5_Suppl.Iii109  0.31
1991 Mullins L, Mullins J. Transgenic approaches to modification of cell and tissue function. Current Opinion in Cell Biology. 3: 192-198. PMID 1883613 DOI: 10.1016/0955-0674(91)90138-O  0.314
1991 Feldmer M, Kaling M, Takahashi S, Mullins JJ, Ganten D. Glucocorticoid- and estrogen-responsive elements in the 5'-flanking region of the rat angiotensinogen gene. Journal of Hypertension. 9: 1005-1012. PMID 1661757 DOI: 10.1097/00004872-199111000-00005  0.318
1991 Sander M, Bader M, Djavidani B, Lee M, Ganten U, Peters J, Mullins J, Vecsei P, Ganten D. 139. Characterization of the hypertensive transgenic rat: role of the adrenal gland Journal of Hypertension. 9. DOI: 10.1097/00004872-199112000-00330  0.386
1991 Lee M, Boehm M, Bader M, Bachmann S, Zimmerman F, Mullins J, Ganten D. 87. High sensitivity to angiotensin converting enzyme inhibition in hypertensive transgenic rats carrying the renin gene of the mouse Journal of Hypertension. 9: S459. DOI: 10.1097/00004872-199112000-00278  0.395
1991 Kaling M, Bunnemann B, Mullins J, Wernicke G, Ganten D. 81. Requirements for expression of the angiotensin gene in tissue cell and transgenic animals Journal of Hypertension. 9: S456. DOI: 10.1097/00004872-199112000-00272  0.36
1991 Feldmer M, Kaling M, Mullins JJ, Ganten D. 48. Glucocorticoid- and estrogen-responsive elements in the 5-region of the rat angiotensinogen gene Journal of Hypertension. 9. DOI: 10.1097/00004872-199112000-00239  0.322
1991 Chung O, Schips T, Qadri F, Ganten D, Mullins J, Unger T. 23. The transgenic mRen2 rat Journal of Hypertension. 9: S431. DOI: 10.1097/00004872-199112000-00214  0.334
1990 Mullins JJ, Peters J, Ganten D. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature. 344: 541-4. PMID 2181319 DOI: 10.1038/344541A0  0.427
1990 Sigmund CD, Jones CA, Mullins JJ, Kim U, Gross KW. Expression of murine renin genes in subcutaneous connective tissue. Proceedings of the National Academy of Sciences of the United States of America. 87: 7993-7. PMID 2172970 DOI: 10.1073/Pnas.87.20.7993  0.341
1990 Sigmund CD, Jones CA, Fabian JR, Mullins JJ, Gross KW. Tissue and cell specific expression of a renin promoter-reporter gene construct in transgenic mice. Biochemical and Biophysical Research Communications. 170: 344-50. PMID 1695507 DOI: 10.1016/0006-291X(90)91280-6  0.366
1990 Ganten D, Mullins J, Peters J, Zhao Y, Bachmann S, Lee M, Munter K. Establishment of transgenic animals bearing additional genes of the renin angiotensin system European Journal of Pharmacology. 183: 1304. DOI: 10.1016/0014-2999(90)94415-T  0.362
1989 Mullins JJ, Sigmund CD, Kane-Haas C, Wu CZ, Pacholec F, Zeng Q, Gross KW. Studies on the regulation of renin genes using transgenic mice. Clinical and Experimental Hypertension. Part a, Theory and Practice. 10: 1157-67. PMID 3066526 DOI: 10.1080/07300077.1988.11878808  0.359
1989 Held WA, Mullins JJ, Kuhn NJ, Gallagher JF, Gu GD, Gross KW. T antigen expression and tumorigenesis in transgenic mice containing a mouse major urinary protein/SV40 T antigen hybrid gene. The Embo Journal. 8: 183-191. DOI: 10.1002/J.1460-2075.1989.Tb03363.X  0.338
1987 Mullins JJ, Zeng Q, Gross KW. Mapping of the mouse atrial natriuretic factor gene. Evidence for tight linkage to the Fv-1 locus. Hypertension. 9: 518-521. PMID 2883119 DOI: 10.1161/01.Hyp.9.5.518  0.314
1985 Craig AG, Mullins JJ, McTurk P, Brammar WJ. A mouse gene family associated with a major submaxillary-gland glycoprotein. The Biochemical Journal. 225: 657-63. PMID 3977853  0.564
1984 Windass JD, Mullins JJ, Beecroft LJ, George H, Meacock PA, Williams BR, Brammar WJ. Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands. Nucleic Acids Research. 12: 1361-76. PMID 6546617  0.534
1982 Mullins JJ, Burt DW, Windass JD, McTurk P, George H, Brammar WJ. Molecular cloning of two distinct renin genes from the DBA/2 mouse. The Embo Journal. 1: 1461-6. PMID 6327270  0.582
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