Ross C. Gruber - Publications

Affiliations: 
Sanofi, Bridgewater, NJ, United States 
Area:
Neuroinflammation and Multiple Sclerosis

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, LaMorte M, Gruber R, Keane A, Loring P, Guo L, Xia TH, Zhang B, Orning P, Lien E, et al. RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis. Cell Reports. 35: 109112. PMID 33979622 DOI: 10.1016/j.celrep.2021.109112  0.33
2019 DuBois JC, Ray AK, Gruber RC, Zhang Y, Aflakpui R, Macian-Juan F, Shafit-Zagardo B. Akt3-Mediated Protection Against Inflammatory Demyelinating Disease. Frontiers in Immunology. 10: 1738. PMID 31404142 DOI: 10.3389/Fimmu.2019.01738  0.746
2018 Mocholi E, Dowling SD, Botbol Y, Gruber RC, Ray AK, Vastert S, Shafit-Zagardo B, Coffer PJ, Macian F. Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy. Cell Reports. 24: 1136-1150. PMID 30067971 DOI: 10.1016/J.Celrep.2018.06.065  0.63
2018 Shafit-Zagardo B, Gruber RC, DuBois JC. The Role of TAM Family Receptors and Ligands in the Nervous System: From Development to Pathobiology. Pharmacology & Therapeutics. PMID 29514053 DOI: 10.1016/J.Pharmthera.2018.03.002  0.663
2017 Ray AK, DuBois JC, Gruber RC, Guzik HM, Gulinello ME, Perumal G, Raine C, Kozakiewicz L, Williamson J, Shafit-Zagardo B. Loss of Gas6 and Axl signaling results in extensive axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure. Glia. PMID 28925029 DOI: 10.1002/Glia.23214  0.727
2015 Gruber RC, LaRocca D, Minchenberg SB, Christophi GP, Hudson CA, Ray AK, Shafit-Zagardo B, Massa PT. The control of reactive oxygen species production by SHP-1 in oligodendrocytes. Glia. PMID 25919645 DOI: 10.1002/Glia.22842  0.764
2014 Gruber RC, Ray AK, Johndrow CT, Guzik H, Burek D, de Frutos PG, Shafit-Zagardo B. Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16320-35. PMID 25471571 DOI: 10.1523/Jneurosci.2449-14.2014  0.74
2014 O'Guin KN, Gruber RC, Raine CS, Guzik HM, Poulos BK, Shafit-Zagardo B. Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures. Asn Neuro. 6: e00135. PMID 24476104 DOI: 10.1042/An20130022  0.653
2013 Tsiperson V, Gruber RC, Goldberg MF, Jordan A, Weinger JG, Macian F, Shafit-Zagardo B. Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 190: 1528-39. PMID 23335751 DOI: 10.4049/Jimmunol.1201387  0.739
2012 Christophi GP, Gruber RC, Panos M, Christophi RL, Jubelt B, Massa PT. Interleukin-33 upregulation in peripheral leukocytes and CNS of multiple sclerosis patients. Clinical Immunology (Orlando, Fla.). 142: 308-19. PMID 22189043 DOI: 10.1016/J.Clim.2011.11.007  0.648
2011 Christophi GP, Christophi JA, Gruber RC, Mihai C, Mejico LJ, Massa PT, Jubelt B. Quantitative differences in the immunomodulatory effects of Rebif and Avonex in IFN-β 1a treated multiple sclerosis patients. Journal of the Neurological Sciences. 307: 41-5. PMID 21658727 DOI: 10.1016/J.Jns.2011.05.024  0.643
2009 Christophi GP, Panos M, Hudson CA, Christophi RL, Gruber RC, Mersich AT, Blystone SD, Jubelt B, Massa PT. Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 742-59. PMID 19398961 DOI: 10.1038/Labinvest.2009.32  0.717
2009 Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT. Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease. Journal of Virology. 83: 522-39. PMID 18987138 DOI: 10.1016/J.Cyto.2008.07.131  0.734
2008 Hudson CA, Christophi GP, Gruber RC, Wilmore JR, Lawrence DA, Massa PT. Induction of IL-33 expression and activity in central nervous system glia. Journal of Leukocyte Biology. 84: 631-43. PMID 18552204 DOI: 10.1189/Jlb.1207830  0.646
2008 Christophi GP, Hudson CA, Gruber R, Christophi CP, Massa PT. Promoter-specific induction of the phosphatase SHP-1 by viral infection and cytokines in CNS glia. Journal of Neurochemistry. 105: 2511-23. PMID 18331586 DOI: 10.1111/J.1471-4159.2008.05337.X  0.715
2008 Christophi GP, Hudson CA, Gruber RC, Christophi CP, Mihai C, Mejico LJ, Jubelt B, Massa PT. SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 243-55. PMID 18209728 DOI: 10.1038/Labinvest.3700720  0.684
2008 Hudson CA, Wilmore JR, Christophi GP, Gruber RC, Massa PT. Direct Induction of Arginase I and Cytokines by IL‐33 in CNS Glia The Faseb Journal. 22: 432-432. DOI: 10.1096/Fasebj.22.2_Supplement.432  0.686
2006 Hudson CA, Christophi GP, Cao L, Gruber RC, Massa PT. Regulation of avoidant behaviors and pain by the anti-inflammatory tyrosine phosphatase SHP-1. Neuron Glia Biology. 2: 235-46. PMID 18250891 DOI: 10.1017/S1740925X07000476  0.692
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