| Year |
Citation |
Score |
| 2023 |
Shafit-Zagardo B, Sidoli S, Goldman JE, DuBois JC, Corboy JR, Strittmatter SM, Guzik H, Edema U, Arackal AG, Botbol YM, Merheb E, Nagra RM, Graff S. TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury. Cells. 12. PMID 37443768 DOI: 10.3390/cells12131734 |
0.334 |
|
| 2019 |
DuBois JC, Ray AK, Gruber RC, Zhang Y, Aflakpui R, Macian-Juan F, Shafit-Zagardo B. Akt3-Mediated Protection Against Inflammatory Demyelinating Disease. Frontiers in Immunology. 10: 1738. PMID 31404142 DOI: 10.3389/Fimmu.2019.01738 |
0.792 |
|
| 2018 |
Mocholi E, Dowling SD, Botbol Y, Gruber RC, Ray AK, Vastert S, Shafit-Zagardo B, Coffer PJ, Macian F. Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy. Cell Reports. 24: 1136-1150. PMID 30067971 DOI: 10.1016/J.Celrep.2018.06.065 |
0.732 |
|
| 2018 |
Shafit-Zagardo B, Gruber RC, DuBois JC. The Role of TAM Family Receptors and Ligands in the Nervous System: From Development to Pathobiology. Pharmacology & Therapeutics. PMID 29514053 DOI: 10.1016/J.Pharmthera.2018.03.002 |
0.76 |
|
| 2017 |
Ray AK, DuBois JC, Gruber RC, Guzik HM, Gulinello ME, Perumal G, Raine C, Kozakiewicz L, Williamson J, Shafit-Zagardo B. Loss of Gas6 and Axl signaling results in extensive axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure. Glia. PMID 28925029 DOI: 10.1002/Glia.23214 |
0.776 |
|
| 2015 |
Gruber RC, LaRocca D, Minchenberg SB, Christophi GP, Hudson CA, Ray AK, Shafit-Zagardo B, Massa PT. The control of reactive oxygen species production by SHP-1 in oligodendrocytes. Glia. PMID 25919645 DOI: 10.1002/Glia.22842 |
0.775 |
|
| 2014 |
Gruber RC, Ray AK, Johndrow CT, Guzik H, Burek D, de Frutos PG, Shafit-Zagardo B. Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16320-35. PMID 25471571 DOI: 10.1523/Jneurosci.2449-14.2014 |
0.779 |
|
| 2014 |
O'Guin KN, Gruber RC, Raine CS, Guzik HM, Poulos BK, Shafit-Zagardo B. Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures. Asn Neuro. 6: e00135. PMID 24476104 DOI: 10.1042/An20130022 |
0.747 |
|
| 2013 |
Tsiperson V, Gruber RC, Goldberg MF, Jordan A, Weinger JG, Macian F, Shafit-Zagardo B. Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 190: 1528-39. PMID 23335751 DOI: 10.4049/Jimmunol.1201387 |
0.76 |
|
| 2012 |
Weinger JG, Davies P, Acker CM, Brosnan CF, Tsiperson V, Bayewitz A, Shafit-Zagardo B. Mice devoid of Tau have increased susceptibility to neuronal damage in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Journal of Neuropathology and Experimental Neurology. 71: 422-33. PMID 22487860 DOI: 10.1097/Nen.0B013E3182540D2E |
0.774 |
|
| 2011 |
Weinger JG, Brosnan CF, Loudig O, Goldberg MF, Macian F, Arnett HA, Prieto AL, Tsiperson V, Shafit-Zagardo B. Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 8: 49. PMID 21569627 DOI: 10.1186/1742-2094-8-49 |
0.781 |
|
| 2010 |
Tsiperson V, Li X, Schwartz GJ, Raine CS, Shafit-Zagardo B. GAS6 enhances repair following cuprizone-induced demyelination. Plos One. 5: e15748. PMID 21203420 DOI: 10.1371/Journal.Pone.0015748 |
0.439 |
|
| 2009 |
Weinger JG, Omari KM, Marsden K, Raine CS, Shafit-Zagardo B. Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions. The American Journal of Pathology. 175: 283-93. PMID 19541935 DOI: 10.2353/Ajpath.2009.080807 |
0.75 |
|
| 2008 |
Hoehn HJ, Kress Y, Sohn A, Brosnan CF, Bourdon S, Shafit-Zagardo B. Axl-/- mice have delayed recovery and prolonged axonal damage following cuprizone toxicity. Brain Research. 1240: 1-11. PMID 18804096 DOI: 10.1016/J.Brainres.2008.08.076 |
0.422 |
|
| 2008 |
Weinger JG, Gohari P, Yan Y, Backer JM, Varnum B, Shafit-Zagardo B. In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation. Journal of Neurochemistry. 106: 134-46. PMID 18346204 DOI: 10.1111/J.1471-4159.2008.05343.X |
0.756 |
|
| 2008 |
Shafit-Zagardo B, Shankar SL, O'Guin K, McMorris FA, Stitt T, Varnum B, Basch RS. Gas6 enhances human oligodendrocyte viability and maturation Journal of Neurochemistry. 81: 46-48. DOI: 10.1046/J.1471-4159.81.S1.15_5.X |
0.451 |
|
| 2006 |
Shankar SL, O'Guin K, Kim M, Varnum B, Lemke G, Brosnan CF, Shafit-Zagardo B. Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5638-48. PMID 16723520 DOI: 10.1523/Jneurosci.5063-05.2006 |
0.416 |
|
| 2005 |
Zamora-Leon SP, Shafit-Zagardo B. Disruption of the actin network enhances MAP-2c and Fyn-induced process outgrowth. Cell Motility and the Cytoskeleton. 62: 110-23. PMID 16145685 DOI: 10.1002/Cm.20090 |
0.74 |
|
| 2005 |
Parashar B, Latha Shankar S, O'Guin K, Butler J, Vikram B, Shafit-Zagardo B. Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective Cox-2 inhibitor. Journal of Neuro-Oncology. 71: 141-8. PMID 15690129 DOI: 10.1007/S11060-004-1721-3 |
0.318 |
|
| 2005 |
Zamora-Leon SP, Bresnick A, Backer JM, Shafit-Zagardo B. Fyn phosphorylates human MAP-2c on tyrosine 67. The Journal of Biological Chemistry. 280: 1962-70. PMID 15536091 DOI: 10.1074/Jbc.M411380200 |
0.751 |
|
| 2004 |
Shankar SL, Krupski M, Parashar B, Okwuaka C, O'Guin K, Mani S, Shafit-Zagardo B. UCN-01 alters phosphorylation of Akt and GSK3beta and induces apoptosis in six independent human neuroblastoma cell lines. Journal of Neurochemistry. 90: 702-11. PMID 15255949 DOI: 10.1111/J.1471-4159.2004.02543.X |
0.36 |
|
| 2003 |
Shankar SL, O'Guin K, Cammer M, McMorris FA, Stitt TN, Basch RS, Varnum B, Shafit-Zagardo B. The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4208-18. PMID 12764109 DOI: 10.1523/Jneurosci.23-10-04208.2003 |
0.471 |
|
| 2002 |
Cosenza MA, Zhao ML, Shankar SL, Shafit-Zagardo B, Lee SC. Up-regulation of MAP2e-expressing oligodendrocytes in the white matter of patients with HIV-1 encephalitis. Neuropathology and Applied Neurobiology. 28: 480-8. PMID 12445164 DOI: 10.1046/J.1365-2990.2002.00420.X |
0.388 |
|
| 2002 |
John GR, Shankar SL, Shafit-Zagardo B, Massimi A, Lee SC, Raine CS, Brosnan CF. Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nature Medicine. 8: 1115-21. PMID 12357247 DOI: 10.1038/Nm781 |
0.377 |
|
| 2002 |
Suzuki SO, Kitai R, Llena J, Lee SC, Goldman JE, Shafit-Zagardo B. MAP-2e, a novel MAP-2 isoform, is expressed in gliomas and delineates tumor architecture and patterns of infiltration. Journal of Neuropathology and Experimental Neurology. 61: 403-12. PMID 12025943 DOI: 10.1093/Jnen/61.5.403 |
0.376 |
|
| 2001 |
Shankar SL, Mani S, O'Guin KN, Kandimalla ER, Agrawal S, Shafit-Zagardo B. Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways. Journal of Neurochemistry. 79: 426-36. PMID 11677271 DOI: 10.1046/J.1471-4159.2001.00596.X |
0.307 |
|
| 2001 |
Zamora-Leon SP, Lee G, Davies P, Shafit-Zagardo B. Binding of Fyn to MAP-2c through an SH3 binding domain. Regulation of the interaction by ERK2. The Journal of Biological Chemistry. 276: 39950-8. PMID 11546790 DOI: 10.1074/Jbc.M107807200 |
0.751 |
|
| 2000 |
Shafit-Zagardo B, Davies P, Rockwood J, Kress Y, Lee SC. Novel microtubule-associated protein-2 isoform is expressed early in human oligodendrocyte maturation. Glia. 29: 233-45. PMID 10642750 DOI: 10.1002/(Sici)1098-1136(20000201)29:3<233::Aid-Glia5>3.0.Co;2-U |
0.471 |
|
| 1999 |
Shafit-Zagardo B, Kress Y, Zhao ML, Lee SC. A novel microtubule-associated protein-2 expressed in oligodendrocytes in multiple sclerosis lesions. Journal of Neurochemistry. 73: 2531-7. PMID 10582615 DOI: 10.1046/J.1471-4159.1999.0732531.X |
0.452 |
|
| 1998 |
Kalcheva N, Rockwood JM, Kress Y, Steiner A, Shafit-Zagardo B. Molecular and functional characteristics of MAP-2a: ability of MAP-2a versus MAP-2b to induce stable microtubules in COS cells. Cell Motility and the Cytoskeleton. 40: 272-85. PMID 9678670 DOI: 10.1002/(Sici)1097-0169(1998)40:3<272::Aid-Cm6>3.0.Co;2-F |
0.344 |
|
| 1998 |
Shafit-Zagardo B, Kalcheva N. Making sense of the multiple MAP-2 transcripts and their role in the neuron. Molecular Neurobiology. 16: 149-62. PMID 9588626 DOI: 10.1007/Bf02740642 |
0.394 |
|
| 1997 |
Shafit-Zagardo B, Kalcheva N, Dickson D, Davies P, Kress Y. Distribution and subcellular localization of high-molecular-weight microtubule-associated protein-2 expressing exon 8 in brain and spinal cord. Journal of Neurochemistry. 68: 862-73. PMID 9003079 DOI: 10.1046/J.1471-4159.1997.68020862.X |
0.397 |
|
| 1997 |
Kalcheva N, Weidenheim KM, Kress Y, Shafit-Zagardo B. Expression of microtubule-associated protein-2a and other novel microtubule-associated protein-2 transcripts in human fetal spinal cord. Journal of Neurochemistry. 68: 383-91. PMID 8978750 DOI: 10.1046/J.1471-4159.1997.68010383.X |
0.394 |
|
| 1995 |
Albala JS, Kress Y, Liu WK, Weidenheim K, Yen SH, Shafit-Zagardo B. Human microtubule-associated protein-2c localizes to dendrites and axons in fetal spinal motor neurons. Journal of Neurochemistry. 64: 2480-90. PMID 7760027 DOI: 10.1046/J.1471-4159.1995.64062480.X |
0.318 |
|
| 1995 |
Kalcheva N, Shafit-Zagardo B. Three unique 5' untranslated regions are spliced to common coding exons of high- and low-molecular-weight microtubule-associated protein-2. Journal of Neurochemistry. 65: 1472-80. PMID 7561840 DOI: 10.1046/J.1471-4159.1995.65041472.X |
0.343 |
|
| 1995 |
Kalcheva N, Albala J, O'Guin K, Rubino H, Garner C, Shafit-Zagardo B. Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms. Proceedings of the National Academy of Sciences of the United States of America. 92: 10894-8. PMID 7479905 DOI: 10.1073/Pnas.92.24.10894 |
0.381 |
|
| 1994 |
Kalcheva N, Albala JS, Binder LI, Shafit-Zagardo B. Localization of specific epitopes on human microtubule-associated protein 2. Journal of Neurochemistry. 63: 2336-41. PMID 7525876 DOI: 10.1046/J.1471-4159.1994.63062336.X |
0.375 |
|
| 1993 |
Shafit-Zagardo B, Sharma N, Berman JW, Bornstein MB, Brosnan CF. CSF-1 expression is upregulated in astrocyte cultures by IL-1 and TNF and affects microglial proliferation and morphology in organotypic cultures. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 11: 189-98. PMID 8328300 DOI: 10.1016/0736-5748(93)90078-R |
0.313 |
|
| 1993 |
Albala JS, Kalcheva N, Shafit-Zagardo B. Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2). Gene. 136: 377-8. PMID 8294038 DOI: 10.1016/0378-1119(93)90502-T |
0.341 |
|
| 1990 |
Aquino DA, Shafit-Zagardo B, Brosnan CF, Norton WT. Expression of glial fibrillary acidic protein and neurofilament mRNA in gliosis induced by experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 54: 1398-404. PMID 1690269 DOI: 10.1111/J.1471-4159.1990.Tb01975.X |
0.313 |
|
| 1989 |
Rubino HM, Dammerman M, Shafit-Zagardo B, Erlichman J. Localization and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2. Neuron. 3: 631-8. PMID 2701845 DOI: 10.1016/0896-6273(89)90273-0 |
0.413 |
|
| 1989 |
Dammerman M, Yen SH, Shafit-Zagardo B. Sequence of a human MAP‐2 region sharing epitopes with Alzheimer neurofibrillary tangles Journal of Neuroscience Research. 24: 487-495. PMID 2481044 DOI: 10.1002/Jnr.490240405 |
0.369 |
|
| 1988 |
Shafit-Zagardo B, Peterson C, Goldman JE. Rapid increases in glial fibrillary acidic protein mRNA and protein levels in the copper-deficient, brindled mouse. Journal of Neurochemistry. 51: 1258-66. PMID 3047319 DOI: 10.1111/J.1471-4159.1988.Tb03095.X |
0.317 |
|
| 1988 |
Shafit-Zagardo B, Kume-Iwaki A, Goldman JE. Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase C-dependent mechanisms. Glia. 1: 346-54. PMID 2465997 DOI: 10.1002/Glia.440010507 |
0.368 |
|
| 1988 |
Dammerman M, Goldstein M, Yen SHC, Shafit-Zagardo B. Isolation and characterization of cDNA clones encoding epitopes shared with Alzheimer neurofibrillary tangles. Journal of Neuroscience Research. 19: 43-51. PMID 2449545 DOI: 10.1002/Jnr.490190107 |
0.364 |
|
| 1987 |
Shafit-Zagardo B, Peterson C, Goldman JE. INCREASES IN GFAP AND GFAP mRNA IN BRINDLED MOUSE CNS. Journal of Neuropathology and Experimental Neurology. 46: 361. DOI: 10.1097/00005072-198705000-00095 |
0.312 |
|
| 1980 |
Shafit-Zagardo B, Devine EA, Desnick RJ. Electrophoretic separation of neutral and acid beta-glucosidase isozymes in human tissues. Biochimica Et Biophysica Acta. 614: 459-65. PMID 6773581 DOI: 10.1016/0005-2744(80)90235-1 |
0.32 |
|
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