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Hans Leuenberger - Publications

Affiliations: 
1963-1971 Physics University of Basel, Basel, Basel-Stadt, Switzerland 
 1982-2006 Pharmaceutical Sciences University of Basel, Basel, Basel-Stadt, Switzerland 
Area:
Pharmaceutical Technology, Dosage Form Design, Application of Percolation Theory, Physical Pharmacy
Website:
www.ifiip.ch
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63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Leuenberger H, Leuenberger MN. Impact of the digital revolution on the future of pharmaceutical formulation science. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 87: 100-11. PMID 26876764 DOI: 10.1016/J.Ejps.2016.02.005  0.347
2013 Kimura G, Puchkov M, Leuenberger H. An attempt to calculate in silico disintegration time of tablets containing mefenamic acid, a low water-soluble drug. Journal of Pharmaceutical Sciences. 102: 2166-78. PMID 23613462 DOI: 10.1002/Jps.23541  0.342
2011 Hadžović E, Betz G, Hadžidedić S, El-Arini SK, Leuenberger H. Investigation of compressibility and compactibility parameters of roller compacted Theophylline and its binary mixtures. International Journal of Pharmaceutics. 416: 97-103. PMID 21704142 DOI: 10.1016/J.Ijpharm.2011.06.012  0.369
2010 Hadzović E, Betz G, Hadzidedić S, El-Arini SK, Leuenberger H. Roller compaction of different pseudopolymorphic forms of theophylline: Effect on compressibility and tablet properties. International Journal of Pharmaceutics. 396: 53-62. PMID 20600735 DOI: 10.1016/J.Ijpharm.2010.06.009  0.361
2010 Sehić S, Betz G, Hadzidedić S, El-Arini SK, Leuenberger H. Investigation of intrinsic dissolution behavior of different carbamazepine samples. International Journal of Pharmaceutics. 386: 77-90. PMID 19900519 DOI: 10.1016/J.Ijpharm.2009.10.051  0.329
2010 Pašić M, Betz G, Hadžidedić Š, El-Arini SK, Leuenberger H. Investigation and development of robust process for direct pelletization of lansoprazole in fluidized bed rotary processor using experimental design Journal of Drug Delivery Science and Technology. 20: 367-376. DOI: 10.1016/S1773-2247(10)50061-3  0.37
2009 Leuenberger H, Puchkov M, Krausbauer E, Betz G. Manufacturing pharmaceutical granules: Is the granulation end-point a myth? Powder Technology. 189: 141-148. DOI: 10.1016/J.Powtec.2008.04.005  0.357
2008 Krausbauer E, Puchkov M, Betz G, Leuenberger H. Rational estimation of the optimum amount of non-fibrous disintegrant applying percolation theory for binary fast disintegrating formulation. Journal of Pharmaceutical Sciences. 97: 529-41. PMID 17879295 DOI: 10.1002/Jps.21163  0.399
2007 Kimura G, Puchkov M, Betz G, Leuenberger H. Percolation theory and the role of maize starch as a disintegrant for a low water-soluble drug. Pharmaceutical Development and Technology. 12: 11-9. PMID 17484140 DOI: 10.1080/10837450601166494  0.383
2006 Leuenberger H. Pharmaceutical technology : Drug delivery, formulation, and process research Chimia. 60: 40-45. DOI: 10.2533/000942906777675092  0.342
2006 Leuenberger H, Plitzko M, Puchkov M. Spray Freeze Drying in a Fluidized Bed at Normal and Low Pressure Drying Technology. 24: 711-719. DOI: 10.1080/07373930600684932  0.348
2005 Hernandez-Perni G, Leuenberger H. The characterization of aprotic polar liquids and percolation phenomena in DMSO/water mixtures. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 61: 201-13. PMID 16061369 DOI: 10.1016/J.Ejpb.2005.05.008  0.32
2005 Iida K, Todo H, Okamoto H, Danjo K, Leuenberger H. Preparation of dry powder inhalation with lactose carrier particles surface-coated using a Wurster fluidized bed. Chemical & Pharmaceutical Bulletin. 53: 431-4. PMID 15802846 DOI: 10.1248/Cpb.53.431  0.322
2005 Leuenberger H, Lanz M. Pharmaceutical powder technology — from art to science: the challenge of the FDA's Process Analytical Technology initiative Advanced Powder Technology. 16: 3-25. DOI: 10.1163/1568552053166683  0.32
2004 von Orelli J, Leuenberger H. Search for technological reasons to develop a capsule or a tablet formulation with respect to wettability and dissolution. International Journal of Pharmaceutics. 287: 135-45. PMID 15541920 DOI: 10.1016/J.Ijpharm.2004.09.006  0.35
2004 Betz G, Bürgin PJ, Leuenberger H. Power consumption measurement and temperature recording during granulation. International Journal of Pharmaceutics. 272: 137-49. PMID 15019077 DOI: 10.1016/J.Ijpharm.2003.12.005  0.332
2004 Werani J, Grünberg M, Ober C, Leuenberger H. Semicontinuous granulation - The process of choice for the production of pharmaceutical granules? Powder Technology. 140: 163-168. DOI: 10.1016/J.Powtec.2004.01.021  0.308
2003 Betz G, Junker-Bürgin P, Leuenberger H. Batch and continuous processing in the production of pharmaceutical granules. Pharmaceutical Development and Technology. 8: 289-97. PMID 12901694 DOI: 10.1081/Pdt-120022157  0.351
2003 Betz G, Bürgin PJ, Leuenberger H. Power consumption profile analysis and tensile strength measurements during moist agglomeration. International Journal of Pharmaceutics. 252: 11-25. PMID 12550777 DOI: 10.1016/S0378-5173(02)00601-4  0.336
2003 Iida K, Hayakawa Y, Okamoto H, Danjo K, Leuenberger H. Preparation of dry powder inhalation by surface treatment of lactose carrier particles. Chemical & Pharmaceutical Bulletin. 51: 1-5. PMID 12520118 DOI: 10.1248/Cpb.51.1  0.332
2003 Leuenberger H. Scale-up in the 4th dimension in the field of granulation and drying or how to avoid classical scale-up Powder Technology. 130: 225-230. DOI: 10.1016/S0032-5910(02)00270-X  0.31
2002 Stengele A, Rey S, Leuenberger H. A novel approach to the characterization of polar liquids. Part 2: binary mixtures. International Journal of Pharmaceutics. 241: 231-40. PMID 12100851 DOI: 10.1016/S0378-5173(02)00233-8  0.328
2002 Leuenberger H. Spray freeze-drying - the process of choice for low water soluble drugs? Journal of Nanoparticle Research. 4: 111-119. DOI: 10.1023/A:1020135603052  0.387
2001 Leuenberger H. New trends in the production of pharmaceutical granules: the classical batch concept and the problem of scale-up. European Journal of Pharmaceutics and Biopharmaceutics. 52: 279-288. PMID 11677070 DOI: 10.1016/S0939-6411(01)00200-4  0.347
2001 Iida K, Hayakawa Y, Okamoto H, Danjo K, Leuenberger H. Evaluation of flow properties of dry powder inhalation of salbutamol sulfate with lactose carrier. Chemical & Pharmaceutical Bulletin. 49: 1326-1330. PMID 11605663 DOI: 10.1248/Cpb.49.1326  0.376
2001 Stengele A, Rey S, Leuenberger H. A novel approach to the characterization of polar liquids. Part 1: pure liquids. International Journal of Pharmaceutics. 225: 123-134. PMID 11489560 DOI: 10.1016/S0378-5173(01)00771-2  0.319
2001 Mann A, Kiefer M, Leuenberger H. Thermal sterilization of heat‐sensitive products using high‐temperature short‐time sterilization Journal of Pharmaceutical Sciences. 90: 275-287. PMID 11170021 DOI: 10.1002/1520-6017(200103)90:3<275::Aid-Jps3>3.0.Co;2-I  0.314
2000 Kuentz M, Leuenberger H. A new theoretical approach to tablet strength of a binary mixture consisting of a well and a poorly compactable substance. European Journal of Pharmaceutics and Biopharmaceutics. 49: 151-159. PMID 10704898 DOI: 10.1016/S0939-6411(99)00078-8  0.426
2000 Iida K, Leuenberger H, Fueg L, Muller-WALZ R, Okamoto H, Danjo K. Effect of mixing of fine carrier particles on dry powder inhalation property of salbutamol sulfate (SS) Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan. 120: 113-119. PMID 10655787 DOI: 10.1248/Yakushi1947.120.1_113  0.347
2000 Kuentz M, Leuenberger H. A new model for the hardness of a compacted particle system, applied to tablets of pharmaceutical polymers Powder Technology. 111: 145-153. DOI: 10.1016/S0032-5910(00)00250-3  0.383
1999 Siegmund C, Leuenberger H. Percolation theory, conductivity and dissolution of hydrophilic suppository bases (PEG systems). International Journal of Pharmaceutics. 189: 187-196. PMID 10536247 DOI: 10.1016/S0378-5173(99)00246-X  0.301
1999 Iida K, Leuenberger H, Fueg L, Muller-WALZ R, Danjo K. Effect of separation characteristics between salbutamol sulfate (SS) particles and model carrier excipients on dry powder for inhalation Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan. 119: 752-762. PMID 10518459 DOI: 10.1248/Yakushi1947.119.10_752  0.362
1999 Kuentz M, Leuenberger H, Kolb M. Fracture in disordered media and tensile strength of microcrystalline cellulose tablets at low relative densities. International Journal of Pharmaceutics. 182: 243-255. PMID 10341313 DOI: 10.1016/S0378-5173(99)00081-2  0.348
1999 Leuenberger H. The application of percolation theory in powder technology Advanced Powder Technology. 10: 323-352. DOI: 10.1163/156855299X00190  0.326
1998 Bourquin J, Schmidli H, Hoogevest Pv, Leuenberger H. Pitfalls of artificial neural networks (ANN) modelling technique for data sets containing outlier measurements using a study on mixture properties of a direct compressed dosage form European Journal of Pharmaceutical Sciences. 7: 17-28. PMID 9845774 DOI: 10.1016/S0928-0987(97)10027-6  0.336
1998 El-Arini SK, Giron D, Leuenberger H. Solubility Properties of Racemic Praziquantel and Its Enantiomers Pharmaceutical Development and Technology. 3: 557-564. PMID 9834959 DOI: 10.3109/10837459809028638  0.33
1998 Bourquin J, Schmidli H, Hoogevest Pv, Leuenberger H. Comparison of artificial neural networks (ANN) with classical modelling techniques using different experimental designs and data from a galenical study on a solid dosage form. European Journal of Pharmaceutical Sciences. 6: 287-300. PMID 9795084 DOI: 10.1016/S0928-0987(97)10025-2  0.316
1998 El-Arini SK, Leuenberger H. Dissolution properties of praziquantel–PVP systems Pharmaceutica Acta Helvetiae. 73: 89-94. PMID 9700937 DOI: 10.1016/S0031-6865(97)00051-4  0.359
1998 Kuentz M, Leuenberger H. Modified Young's Modulus of Microcrystalline Cellulose Tablets and the Directed Continuum Percolation Model Pharmaceutical Development and Technology. 3: 13-19. PMID 9532596 DOI: 10.3109/10837459809028475  0.351
1997 Frederiksen L, Anton K, Van Hoogevest P, Keller HR, Leuenberger H. Preparation of liposomes encapsulating water-soluble compounds using supercritical carbon dioxide Journal of Pharmaceutical Sciences. 86: 921-928. PMID 9269870 DOI: 10.1021/Js960403Q  0.304
1997 Leuenberger H, Ineichen L. Percolation theory and physics of compression European Journal of Pharmaceutics and Biopharmaceutics. 44: 269-272. DOI: 10.1016/S0939-6411(97)00130-6  0.356
1996 El-Arini SK, Leuenberger H. Dissolution Properties of Praziquantel-β-cyclodextrin Systems Pharmaceutical Development and Technology. 1: 307-315. PMID 9552314 DOI: 10.3109/10837459609022600  0.356
1996 Müller BG, Leuenberger H, Kissel T. Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique. Pharmaceutical Research. 13: 32-37. PMID 8668675 DOI: 10.1023/A:1016064930502  0.365
1996 Caraballo I, Millán M, Rabasco AM, Leuenberger H. Zero-order release periods in inert matrices. Influence of the distance to the percolation threshold Pharmaceutica Acta Helvetiae. 71: 335-339. DOI: 10.1016/S0031-6865(96)00023-4  0.37
1996 Caraballo I, Fernández-Arévalo M, Millán M, Rabasco AM, Leuenberger H. Study of percolation thresholds in ternary tablets International Journal of Pharmaceutics. 139: 177-186. DOI: 10.1016/0378-5173(96)04603-0  0.354
1995 Ei-Arini SK, Leuenberger H. Modelling of drug release from polymer matrices: Effect of drug loading International Journal of Pharmaceutics. 121: 141-148. DOI: 10.1016/0378-5173(94)00418-5  0.35
1995 Leuenberger H, Bonny JD, Kolb M. Percolation effects in matrix-type controlled drug release systems International Journal of Pharmaceutics. 115: 217-224. DOI: 10.1016/0378-5173(94)00266-8  0.369
1994 Isele U, Hoogevest PV, Hilfiker R, Capraro H, Schieweck K, Leuenberger H. Large‐Scale Production of Liposomes Containing Monomeric Zinc Phthalocyanine by Controlled Dilution of Organic Solvents Journal of Pharmaceutical Sciences. 83: 1608-1616. PMID 7891283 DOI: 10.1002/Jps.2600831117  0.3
1994 Caraballo I, Fernandez-Arevalo M, Holgado MA, Rabasco AM, Leuenberger H. Study of the release mechanism of carteolol inert matrix tablets on the basis of percolation theory International Journal of Pharmaceutics. 109: 229-236. DOI: 10.1016/0378-5173(94)90385-9  0.317
1994 Bausch A, Leuenberger H. Wet spherical agglomeration of proteins as a new method to prepare parenteral fast soluble dosage forms International Journal of Pharmaceutics. 101: 63-70. DOI: 10.1016/0378-5173(94)90076-0  0.315
1994 Luginbühl R, Leuenberger H. Use of percolation theory to interpret water uptake, disintegration time and intrinsic dissolution rate of tablets consisting of binary mixtures Pharmaceutica Acta Helvetiae. 69: 127-134. DOI: 10.1016/0031-6865(94)90013-2  0.334
1993 Leu R, Leuenberger H. The application of percolation theory to the compaction of pharmaceutical powders International Journal of Pharmaceutics. 90: 213-219. DOI: 10.1016/0378-5173(93)90193-J  0.334
1993 Bonny JD, Leuenberger H. Matrix type controlled release systems II. Percolation effects in non-swellable matrices Pharmaceutica Acta Helvetiae. 68: 25-33. DOI: 10.1016/0031-6865(93)90005-Q  0.375
1992 Leuenberger H, Leu R. Formation of a Tablet: A Site and Bond Percolation Phenomenon Journal of Pharmaceutical Sciences. 81: 976-982. PMID 1432623 DOI: 10.1002/Jps.2600811004  0.344
1992 Leuenberger H, Leu R, Bonny JD. Application of Percolation Theory and Fractal Geometry to Tablet Compaction Drug Development and Industrial Pharmacy. 18: 723-766. DOI: 10.3109/03639049209058559  0.366
1991 Mumenthaler M, Leuenberger H. Atmospheric spray-freeze drying: a suitable alternative in freeze-drying technology International Journal of Pharmaceutics. 72: 97-110. DOI: 10.1016/0378-5173(91)90047-R  0.352
1990 Blattner D, Kolb M, Leuenberger H. Percolation Theory and Compactibility of Binary Powder Systems Pharmaceutical Research. 7: 113-117. PMID 2308890 DOI: 10.1023/A:1015864415693  0.367
1989 Leuenberger H, Bonny JD, Lerk CF, Vromans H. Relation between crushing strength and internal specific surface area of lactose compacts International Journal of Pharmaceutics. 52: 91-100. DOI: 10.1016/0378-5173(89)90282-2  0.322
1989 Usteri M, Leuenberger H. Agglomeration of binary mixtures in a high-speed mixer International Journal of Pharmaceutics. 55: 135-141. DOI: 10.1016/0378-5173(89)90034-3  0.372
1988 Holman LE, Leuenberger H. The relationship between solid fraction and mechanical properties of compacts — the percolation theory model approach International Journal of Pharmaceutics. 46: 35-44. DOI: 10.1016/0378-5173(88)90007-5  0.351
1986 Leuenberger H, Rohera BD. Fundamentals of Powder Compression. II. The Compression of Binary Powder Mixtures. Pharmaceutical Research. 3: 65-74. PMID 24271463 DOI: 10.1023/A:1016333101427  0.353
1986 Leuenberger H, Rohera BD. Fundamentals of Powder Compression. I. The Compactibility and Compressibility of Pharmaceutical Powders Pharmaceutical Research. 3: 12-22. PMID 24271352 DOI: 10.1023/A:1016364613722  0.365
1982 Leuenberger H. The compressibility and compactibility of powder systems International Journal of Pharmaceutics. 12: 41-55. DOI: 10.1016/0378-5173(82)90132-6  0.32
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