| Year |
Citation |
Score |
| 2019 |
Merkel OM, Marsh LM, Garn H, Kissel T. Flow Cytometry-Based Cell Type-Specific Assessment of Target Regulation by Pulmonary siRNA Delivery. Methods in Molecular Biology (Clifton, N.J.). 1943: 365-375. PMID 30838629 DOI: 10.1007/978-1-4939-9092-4_24 |
0.581 |
|
| 2017 |
Beck-Broichsitter M, Bohr A, Aragão-Santiago L, Klingl A, Kissel T. Formulation and process considerations for the design of sildenafil-loaded polymeric microparticles by vibrational spray-drying. Pharmaceutical Development and Technology. 22: 691-698. PMID 26740242 DOI: 10.3109/10837450.2015.1098661 |
0.383 |
|
| 2016 |
Beck-Broichsitter M, Samsonova O, Nguyen J, Schmehl T, Seeger W, Kissel T. Influence of amine-modified poly(vinyl alcohol)s on vibrating-membrane nebulizer performance and lung toxicity. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 86: 34-40. PMID 26946442 DOI: 10.1016/J.Ejps.2016.02.023 |
0.701 |
|
| 2016 |
Beck-Broichsitter M, Stoisiek K, Bohr A, Aragão-Santiago L, Gessler T, Seeger W, Kissel T. Potential of the isolated lung technique for the examination of sildenafil absorption from lung-delivered poly(lactide-co-glycolide) microparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 226: 15-20. PMID 26849917 DOI: 10.1016/J.Jconrel.2016.01.057 |
0.35 |
|
| 2015 |
Liu L, Zheng M, Librizzi D, Renette T, Merkel O, Kissel T. Efficient and tumor targeted siRNA delivery mediated by polyethylenimine-graft-polycaprolactone-block-poly (ethylene glycol)-folate (PEI- PCL-PEG-Fol). Molecular Pharmaceutics. PMID 26641134 DOI: 10.1021/Acs.Molpharmaceut.5B00575 |
0.691 |
|
| 2015 |
Beck-Broichsitter M, Hecker A, Kosanovic D, Schmehl T, Gessler T, Weissmann N, Ghofrani HA, Kissel T, Seeger W, Schermuly RT. Prolonged vasodilatory response to nanoencapsulated sildenafil in pulmonary hypertension. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26393885 DOI: 10.1016/J.Nano.2015.08.009 |
0.314 |
|
| 2015 |
Beck-Broichsitter M, Paulus IE, Greiner A, Kissel T. Modified vibrating-mesh nozzles for advanced spray-drying applications. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 92: 96-101. PMID 25753195 DOI: 10.1016/J.Ejpb.2015.03.001 |
0.356 |
|
| 2015 |
Beck-Broichsitter M, Strehlow B, Kissel T. Direct fractionation of spray-dried polymeric microparticles by inertial impaction Powder Technology. 286: 311-317. DOI: 10.1016/J.Powtec.2015.08.033 |
0.32 |
|
| 2014 |
Ganas C, Weiß A, Nazarenus M, Rösler S, Kissel T, Rivera Gil P, Parak WJ. Biodegradable capsules as non-viral vectors for in vitro delivery of PEI/siRNA polyplexes for efficient gene silencing. Journal of Controlled Release : Official Journal of the Controlled Release Society. 196: 132-8. PMID 25451543 DOI: 10.1016/J.Jconrel.2014.10.006 |
0.404 |
|
| 2014 |
Merkel OM, Kissel T. Quo vadis polyplex? Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 415-23. PMID 24933599 DOI: 10.1016/J.Jconrel.2014.06.009 |
0.645 |
|
| 2014 |
Merkel OM, Rubinstein I, Kissel T. siRNA delivery to the lung: what's new? Advanced Drug Delivery Reviews. 75: 112-28. PMID 24907426 DOI: 10.1016/J.Addr.2014.05.018 |
0.605 |
|
| 2014 |
Hellmund M, Zhou H, Samsonova O, Welker P, Kissel T, Haag R. Functionalized polyglycerol amine nanogels as nanocarriers for DNA. Macromolecular Bioscience. 14: 1215-21. PMID 24863397 DOI: 10.1002/Mabi.201400144 |
0.395 |
|
| 2014 |
Endres T, Zheng M, Kılıç A, Turowska A, Beck-Broichsitter M, Renz H, Merkel OM, Kissel T. Amphiphilic biodegradable PEG-PCL-PEI triblock copolymers for FRET-capable in vitro and in vivo delivery of siRNA and quantum dots. Molecular Pharmaceutics. 11: 1273-81. PMID 24592902 DOI: 10.1021/Mp400744A |
0.655 |
|
| 2014 |
Beck-Broichsitter M, Dalla-Bona AC, Kissel T, Seeger W, Schmehl T. Polymer nanoparticle-based controlled pulmonary drug delivery. Methods in Molecular Biology (Clifton, N.J.). 1141: 133-45. PMID 24567136 DOI: 10.1007/978-1-4939-0363-4_8 |
0.39 |
|
| 2014 |
Chu D, Beck-Broichsitter M, Curdy C, Riebesehl B, Kissel T. Feasibility of macrophage mediated on-demand drug release from surface eroding poly(ethylene carbonate). International Journal of Pharmaceutics. 465: 1-4. PMID 24530387 DOI: 10.1016/J.Ijpharm.2014.02.005 |
0.355 |
|
| 2013 |
Chu D, Curdy C, Riebesehl B, Beck-Broichsitter M, Kissel T. In situ forming parenteral depot systems based on poly(ethylene carbonate): effect of polymer molecular weight on model protein release. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 85: 1245-9. PMID 23791717 DOI: 10.1016/J.Ejpb.2013.05.020 |
0.395 |
|
| 2013 |
Chu D, Curdy C, Riebesehl B, Zhang Y, Beck-Broichsitter M, Kissel T. Enzyme-responsive surface erosion of poly(ethylene carbonate) for controlled drug release. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 85: 1232-7. PMID 23639738 DOI: 10.1016/J.Ejpb.2013.04.011 |
0.382 |
|
| 2013 |
Schnieders J, Gbureck U, Germershaus O, Kratz M, Jones DB, Kissel T. Ex vivo human trabecular bone model for biocompatibility evaluation of calcium phosphate composites modified with spray dried biodegradable microspheres. Advanced Healthcare Materials. 2: 1361-9. PMID 23568426 DOI: 10.1002/Adhm.201200390 |
0.669 |
|
| 2013 |
Bege N, Renette T, Endres T, Beck-Broichsitter M, Hänggi D, Kissel T. In situ forming nimodipine depot system based on microparticles for the treatment of posthemorrhagic cerebral vasospasm. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 84: 99-105. PMID 23298622 DOI: 10.1016/J.Ejpb.2012.12.016 |
0.325 |
|
| 2013 |
Merkel OM, Marsh LM, Garn H, Kissel T. Flow cytometry-based cell type-specific assessment of target regulation by pulmonary siRNA delivery. Methods in Molecular Biology (Clifton, N.J.). 948: 263-73. PMID 23070776 DOI: 10.1007/978-1-62703-140-0_18 |
0.617 |
|
| 2013 |
Samsonova O, Glinca S, Biela A, Pfeiffer C, Dayyoub E, Sahin D, Klebe G, Kissel T. The use of isothermal titration calorimetry and molecular dynamics to show variability in DNA transfection performance. Acta Biomaterialia. 9: 4994-5002. PMID 23059414 DOI: 10.1016/J.Actbio.2012.10.006 |
0.418 |
|
| 2012 |
Zheng M, Pavan GM, Neeb M, Schaper AK, Danani A, Klebe G, Merkel OM, Kissel T. Targeting the blind spot of polycationic nanocarrier-based siRNA delivery. Acs Nano. 6: 9447-54. PMID 23036046 DOI: 10.1021/Nn301966R |
0.66 |
|
| 2012 |
Liu L, Patra A, Scherf U, Kissel T. Polyfluorene Nanoparticles Coated with Folate-Functionalized Triblock Copolymer: Effective Agents for Targeted Cell Imaging Macromolecular Bioscience. 12: 1384-1390. PMID 22926969 DOI: 10.1002/Mabi.201200144 |
0.355 |
|
| 2012 |
Beck-Broichsitter M, Kleimann P, Schmehl T, Betz T, Bakowsky U, Kissel T, Seeger W. Impact of lyoprotectants for the stabilization of biodegradable nanoparticles on the performance of air-jet, ultrasonic, and vibrating-mesh nebulizers. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 82: 272-80. PMID 22820646 DOI: 10.1016/J.Ejpb.2012.07.004 |
0.329 |
|
| 2012 |
Reul R, Nguyen J, Biela A, Marxer E, Bakowsky U, Klebe G, Kissel T. Biophysical and biological investigation of DNA nano-complexes with a non-toxic, biodegradable amine-modified hyperbranched polyester. International Journal of Pharmaceutics. 436: 97-105. PMID 22814220 DOI: 10.1016/J.Ijpharm.2012.06.065 |
0.678 |
|
| 2012 |
Zheng M, Librizzi D, Kılıç A, Liu Y, Renz H, Merkel OM, Kissel T. Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol) copolymers. Biomaterials. 33: 6551-8. PMID 22710127 DOI: 10.1016/J.Biomaterials.2012.05.055 |
0.67 |
|
| 2012 |
Renette T, Librizzi D, Endres T, Merkel O, Beck-Broichsitter M, Bege N, Petersen H, Curdy C, Kissel T. Poly(ethylene carbonate) nanoparticles as carrier system for chemotherapy showing prolonged in vivo circulation and anti-tumor efficacy. Macromolecular Bioscience. 12: 970-8. PMID 22648959 DOI: 10.1002/Mabi.201100499 |
0.625 |
|
| 2012 |
Debus H, Beck-Broichsitter M, Kissel T. Optimized preparation of pDNA/poly(ethylene imine) polyplexes using a microfluidic system. Lab On a Chip. 12: 2498-506. PMID 22552347 DOI: 10.1039/C2Lc40176B |
0.405 |
|
| 2012 |
Liu L, Zheng M, Renette T, Kissel T. Modular synthesis of folate conjugated ternary copolymers: polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate for targeted gene delivery. Bioconjugate Chemistry. 23: 1211-20. PMID 22548308 DOI: 10.1021/Bc300025D |
0.42 |
|
| 2012 |
Endres T, Zheng M, Beck-Broichsitter M, Samsonova O, Debus H, Kissel T. Optimising the self-assembly of siRNA loaded PEG-PCL-lPEI nano-carriers employing different preparation techniques. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 583-91. PMID 22525320 DOI: 10.1016/J.Jconrel.2012.04.013 |
0.388 |
|
| 2012 |
Endres T, Zheng M, Beck-Broichsitter M, Kissel T. Lyophilised ready-to-use formulations of PEG-PCL-PEI nano-carriers for siRNA delivery. International Journal of Pharmaceutics. 428: 121-4. PMID 22414387 DOI: 10.1016/J.Ijpharm.2012.03.003 |
0.403 |
|
| 2012 |
Benfer M, Reul R, Betz T, Kissel T. Folic acid-decorated nanocomposites prepared by a simple solvent displacement method. Macromolecular Bioscience. 12: 438-45. PMID 22351521 DOI: 10.1002/Mabi.201100344 |
0.365 |
|
| 2012 |
Bege N, Steinmüller SO, Kalinowski M, Reul R, Klaus S, Petersen H, Curdy C, Janek J, Kissel T. Drug eluting stents based on Poly(ethylene carbonate): optimization of the stent coating process. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 80: 562-70. PMID 22209978 DOI: 10.1016/J.Ejpb.2011.12.006 |
0.335 |
|
| 2012 |
Beck-Broichsitter M, Merkel OM, Kissel T. Controlled pulmonary drug and gene delivery using polymeric nano-carriers. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 214-24. PMID 22192571 DOI: 10.1016/J.Jconrel.2011.12.004 |
0.638 |
|
| 2012 |
Zhang Y, Zheng M, Kissel T, Agarwal S. Design and biophysical characterization of bioresponsive degradable poly(dimethylaminoethyl methacrylate) based polymers for in vitro DNA transfection. Biomacromolecules. 13: 313-22. PMID 22191470 DOI: 10.1021/Bm2015174 |
0.427 |
|
| 2012 |
Seidel N, Sitterberg J, Vornholt W, Bakowsky U, Keusgen M, Kissel T. Predicting protein instability in sustained protein delivery systems using spectral-phase interference. Biomaterials. 33: 1929-38. PMID 22136720 DOI: 10.1016/J.Biomaterials.2011.11.037 |
0.367 |
|
| 2012 |
Benfer M, Kissel T. Cellular uptake mechanism and knockdown activity of siRNA-loaded biodegradable DEAPA-PVA-g-PLGA nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 80: 247-56. PMID 22085653 DOI: 10.1016/J.Ejpb.2011.10.021 |
0.41 |
|
| 2012 |
Beck-Broichsitter M, Schweiger C, Schmehl T, Gessler T, Seeger W, Kissel T. Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 158: 329-35. PMID 22063006 DOI: 10.1016/J.Jconrel.2011.10.030 |
0.316 |
|
| 2012 |
Beck-Broichsitter M, Kleimann P, Gessler T, Seeger W, Kissel T, Schmehl T. Nebulization performance of biodegradable sildenafil-loaded nanoparticles using the Aeroneb Pro: formulation aspects and nanoparticle stability to nebulization. International Journal of Pharmaceutics. 422: 398-408. PMID 22001839 DOI: 10.1016/J.Ijpharm.2011.10.012 |
0.376 |
|
| 2012 |
Merkel OM, Zheng M, Debus H, Kissel T. Pulmonary gene delivery using polymeric nonviral vectors. Bioconjugate Chemistry. 23: 3-20. PMID 21999216 DOI: 10.1021/Bc200296Q |
0.657 |
|
| 2012 |
Weber ND, Merkel OM, Kissel T, Muñoz-Fernández MÁ. PEGylated poly(ethylene imine) copolymer-delivered siRNA inhibits HIV replication in vitro. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 55-63. PMID 21930169 DOI: 10.1016/J.Jconrel.2011.09.059 |
0.641 |
|
| 2012 |
Beck-Broichsitter M, Schmehl T, Gessler T, Seeger W, Kissel T. Development of a biodegradable nanoparticle platform for sildenafil: formulation optimization by factorial design analysis combined with application of charge-modified branched polyesters. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 469-77. PMID 21930166 DOI: 10.1016/J.Jconrel.2011.09.058 |
0.401 |
|
| 2012 |
Steele TW, Zhao X, Tarcha P, Kissel T. Factors influencing polycation/siRNA colloidal stability toward aerosol lung delivery. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 80: 14-24. PMID 21924355 DOI: 10.1016/J.Ejpb.2011.08.008 |
0.426 |
|
| 2012 |
Merkel OM, Kissel T. Nonviral pulmonary delivery of siRNA. Accounts of Chemical Research. 45: 961-70. PMID 21905687 DOI: 10.1021/Ar200110P |
0.662 |
|
| 2012 |
Zheng M, Liu Y, Samsonova O, Endres T, Merkel O, Kissel T. Amphiphilic and biodegradable hy-PEI-g-PCL-b-PEG copolymers efficiently mediate transgene expression depending on their graft density. International Journal of Pharmaceutics. 427: 80-7. PMID 21600970 DOI: 10.1016/J.Ijpharm.2011.05.017 |
0.668 |
|
| 2012 |
Zhang Y, Chu D, Zheng M, Kissel T, Agarwal S. Biocompatible and degradable poly(2-hydroxyethyl methacrylate) based polymers for biomedical applications Polymer Chemistry. 3: 2752-2759. DOI: 10.1039/C2Py20403G |
0.392 |
|
| 2011 |
Schnieders J, Gbureck U, Vorndran E, Schossig M, Kissel T. The effect of porosity on drug release kinetics from vancomycin microsphere/calcium phosphate cement composites. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 99: 391-8. PMID 21948487 DOI: 10.1002/Jbm.B.31910 |
0.336 |
|
| 2011 |
Trapani A, Denora N, Iacobellis G, Sitterberg J, Bakowsky U, Kissel T. Methotrexate-loaded chitosan- and glycol chitosan-based nanoparticles: a promising strategy for the administration of the anticancer drug to brain tumors. Aaps Pharmscitech. 12: 1302-11. PMID 21948322 DOI: 10.1208/S12249-011-9695-X |
0.331 |
|
| 2011 |
Endres TK, Beck-Broichsitter M, Samsonova O, Renette T, Kissel TH. Self-assembled biodegradable amphiphilic PEG-PCL-lPEI triblock copolymers at the borderline between micelles and nanoparticles designed for drug and gene delivery. Biomaterials. 32: 7721-31. PMID 21782238 DOI: 10.1016/j.biomaterials.2011.06.064 |
0.338 |
|
| 2011 |
Liu Y, Samsonova O, Sproat B, Merkel O, Kissel T. Biophysical characterization of hyper-branched polyethylenimine-graft-polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 153: 262-8. PMID 21549166 DOI: 10.1016/J.Jconrel.2011.04.017 |
0.685 |
|
| 2011 |
Bege N, Renette T, Jansch M, Reul R, Merkel O, Petersen H, Curdy C, Müller RH, Kissel T. Biodegradable poly(ethylene carbonate) nanoparticles as a promising drug delivery system with "stealth" potential. Macromolecular Bioscience. 11: 897-904. PMID 21472988 DOI: 10.1002/Mabi.201000496 |
0.641 |
|
| 2011 |
Merkel OM, Urbanics R, Bedocs P, Rozsnyay Z, Rosivall L, Toth M, Kissel T, Szebeni J. In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly(ethylene glycol) block copolymers. Biomaterials. 32: 4936-42. PMID 21459440 DOI: 10.1016/J.Biomaterials.2011.03.035 |
0.663 |
|
| 2011 |
Beyerle A, Long AS, White PA, Kissel T, Stoeger T. Poly(ethylene imine) nanocarriers do not induce mutations nor oxidative DNA damage in vitro in MutaMouse FE1 cells. Molecular Pharmaceutics. 8: 976-81. PMID 21446747 DOI: 10.1021/Mp1004492 |
0.373 |
|
| 2011 |
Zhao N, Roesler S, Kissel T. Synthesis of a new potential biodegradable disulfide containing poly(ethylene imine)-poly(ethylene glycol) copolymer cross-linked with click cluster for gene delivery. International Journal of Pharmaceutics. 411: 197-205. PMID 21439364 DOI: 10.1016/J.Ijpharm.2011.03.038 |
0.46 |
|
| 2011 |
Kim TI, Rothmund T, Kissel T, Kim SW. Bioreducible polymers with cell penetrating and endosome buffering functionality for gene delivery systems. Journal of Controlled Release : Official Journal of the Controlled Release Society. 152: 110-9. PMID 21352876 DOI: 10.1016/J.Jconrel.2011.02.013 |
0.406 |
|
| 2011 |
Merkel OM, Zheng M, Mintzer MA, Pavan GM, Librizzi D, Maly M, Höffken H, Danani A, Simanek EE, Kissel T. Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems. Journal of Controlled Release : Official Journal of the Controlled Release Society. 153: 23-33. PMID 21342661 DOI: 10.1016/J.Jconrel.2011.02.016 |
0.651 |
|
| 2011 |
Schweiger C, Pietzonka C, Heverhagen J, Kissel T. Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging. International Journal of Pharmaceutics. 408: 130-7. PMID 21315813 DOI: 10.1016/J.Ijpharm.2010.12.046 |
0.376 |
|
| 2011 |
Roesler S, Koch FP, Schmehl T, Weissmann N, Seeger W, Gessler T, Kissel T. Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery. The Journal of Gene Medicine. 13: 123-33. PMID 21308899 DOI: 10.1002/Jgm.1538 |
0.397 |
|
| 2011 |
Reul R, Renette T, Bege N, Kissel T. Nanoparticles for paclitaxel delivery: a comparative study of different types of dendritic polyesters and their degradation behavior. International Journal of Pharmaceutics. 407: 190-6. PMID 21256945 DOI: 10.1016/J.Ijpharm.2011.01.028 |
0.425 |
|
| 2011 |
Beyerle A, Braun A, Merkel O, Koch F, Kissel T, Stoeger T. Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice. Journal of Controlled Release : Official Journal of the Controlled Release Society. 151: 51-6. PMID 21223987 DOI: 10.1016/J.Jconrel.2010.12.017 |
0.644 |
|
| 2011 |
Merkel OM, Beyerle A, Beckmann BM, Zheng M, Hartmann RK, Stöger T, Kissel TH. Polymer-related off-target effects in non-viral siRNA delivery. Biomaterials. 32: 2388-98. PMID 21183213 DOI: 10.1016/J.Biomaterials.2010.11.081 |
0.634 |
|
| 2011 |
Lebhardt T, Roesler S, Uusitalo HP, Kissel T. Surfactant-free redispersible nanoparticles in fast-dissolving composite microcarriers for dry-powder inhalation. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 78: 90-6. PMID 21145394 DOI: 10.1016/J.Ejpb.2010.12.002 |
0.338 |
|
| 2011 |
Beck-Broichsitter M, Ruppert C, Schmehl T, Guenther A, Betz T, Bakowsky U, Seeger W, Kissel T, Gessler T. Biophysical investigation of pulmonary surfactant surface properties upon contact with polymeric nanoparticles in vitro. Nanomedicine : Nanotechnology, Biology, and Medicine. 7: 341-50. PMID 21059405 DOI: 10.1016/J.Nano.2010.10.007 |
0.39 |
|
| 2011 |
Samsonova O, Pfeiffer C, Hellmund M, Merkel OM, Kissel T. Low Molecular Weight pDMAEMA-block-pHEMA Block-Copolymers Synthesized via RAFT-Polymerization: Potential Non-Viral Gene Delivery Agents? Polymers. 3: 693-718. DOI: 10.3390/Polym3020693 |
0.688 |
|
| 2010 |
Merkel OM, Mintzer MA, Simanek EE, Kissel T. Perfectly shaped siRNA delivery. Therapeutic Delivery. 1: 737-42. PMID 22834010 DOI: 10.4155/Tde.10.69 |
0.62 |
|
| 2010 |
Sun J, Bubel K, Chen F, Kissel T, Agarwal S, Greiner A. Nanofibers by green electrospinning of aqueous suspensions of biodegradable block copolyesters for applications in medicine, pharmacy and agriculture. Macromolecular Rapid Communications. 31: 2077-83. PMID 21567634 DOI: 10.1002/Marc.201000379 |
0.364 |
|
| 2010 |
Liu Y, Steele T, Kissel T. Degradation of Hyper-Branched Poly(ethylenimine)-graft-poly(caprolactone)-block-monomethoxyl-poly(ethylene glycol) as a Potential Gene Delivery Vector. Macromolecular Rapid Communications. 31: 1509-15. PMID 21567559 DOI: 10.1002/Marc.201000337 |
0.439 |
|
| 2010 |
Debus H, Baumhof P, Probst J, Kissel T. Delivery of messenger RNA using poly(ethylene imine)-poly(ethylene glycol)-copolymer blends for polyplex formation: biophysical characterization and in vitro transfection properties. Journal of Controlled Release : Official Journal of the Controlled Release Society. 148: 334-43. PMID 20854856 DOI: 10.1016/J.Jconrel.2010.09.007 |
0.427 |
|
| 2010 |
Nguyen J, Reul R, Roesler S, Dayyoub E, Schmehl T, Gessler T, Seeger W, Kissel TH. Amine-modified poly(vinyl alcohol)s as non-viral vectors for siRNA delivery: effects of the degree of amine substitution on physicochemical properties and knockdown efficiency. Pharmaceutical Research. 27: 2670-82. PMID 20848302 DOI: 10.1007/S11095-010-0266-8 |
0.655 |
|
| 2010 |
Beck-Broichsitter M, Thieme M, Nguyen J, Schmehl T, Gessler T, Seeger W, Agarwal S, Greiner A, Kissel T. Novel 'nano in nano' composites for sustained drug delivery: biodegradable nanoparticles encapsulated into nanofiber non-wovens. Macromolecular Bioscience. 10: 1527-35. PMID 20824691 DOI: 10.1002/Mabi.201000100 |
0.701 |
|
| 2010 |
Liu Y, Kemmer A, Keim K, Curdy C, Petersen H, Kissel T. Poly(ethylene carbonate) as a surface-eroding biomaterial for in situ forming parenteral drug delivery systems: a feasibility study. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 76: 222-9. PMID 20650316 DOI: 10.1016/J.Ejpb.2010.07.009 |
0.346 |
|
| 2010 |
Germershaus O, Pickaert G, Konrad J, Krüger U, Kissel T, Haag R. Imidazole and dimethyl aminopropyl-functionalized hyperbranched polymers for nucleic acid transfection. Macromolecular Bioscience. 10: 1055-62. PMID 20602422 DOI: 10.1002/Mabi.201000077 |
0.74 |
|
| 2010 |
Beck-Broichsitter M, Rytting E, Lebhardt T, Wang X, Kissel T. Preparation of nanoparticles by solvent displacement for drug delivery: a shift in the "ouzo region" upon drug loading. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 41: 244-53. PMID 20600881 DOI: 10.1016/J.Ejps.2010.06.007 |
0.407 |
|
| 2010 |
Merkel OM, Mintzer MA, Librizzi D, Samsonova O, Dicke T, Sproat B, Garn H, Barth PJ, Simanek EE, Kissel T. Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity. Molecular Pharmaceutics. 7: 969-83. PMID 20524664 DOI: 10.1021/Mp100101S |
0.664 |
|
| 2010 |
Beyerle A, Irmler M, Beckers J, Kissel T, Stoeger T. Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications. Molecular Pharmaceutics. 7: 727-37. PMID 20429563 DOI: 10.1021/Mp900278X |
0.383 |
|
| 2010 |
Richter A, Olbrich C, Krause M, Hoffmann J, Kissel T. Polymeric Micelles for parenteral delivery of Sagopilone: Physicochemical characterization, novel formulation approaches and their toxicity assessment in vitro as well as in vivo European Journal of Pharmaceutics and Biopharmaceutics. 75: 80-89. PMID 20188169 DOI: 10.1016/J.Ejpb.2010.02.010 |
0.402 |
|
| 2010 |
Pavan GM, Mintzer MA, Simanek EE, Merkel OM, Kissel T, Danani A. Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers. Biomacromolecules. 11: 721-30. PMID 20131771 DOI: 10.1021/Bm901298T |
0.585 |
|
| 2010 |
Richter A, Olbrich C, Krause M, Kissel T. Solubilization of Sagopilone, a poorly water-soluble anticancer drug, using polymeric micelles for parenteral delivery International Journal of Pharmaceutics. 389: 244-253. PMID 20100557 DOI: 10.1016/J.Ijpharm.2010.01.032 |
0.404 |
|
| 2010 |
Beyerle A, Merkel O, Stoeger T, Kissel T. PEGylation affects cytotoxicity and cell-compatibility of poly(ethylene imine) for lung application: structure-function relationships. Toxicology and Applied Pharmacology. 242: 146-54. PMID 19822165 DOI: 10.1016/J.Taap.2009.10.001 |
0.682 |
|
| 2010 |
Mao S, Sun W, Kissel T. Chitosan-based formulations for delivery of DNA and siRNA. Advanced Drug Delivery Reviews. 62: 12-27. PMID 19796660 DOI: 10.1016/J.Addr.2009.08.004 |
0.436 |
|
| 2010 |
Beck-Broichsitter M, Gauss J, Gessler T, Seeger W, Kissel T, Schmehl T. Pulmonary targeting with biodegradable salbutamol-loaded nanoparticles. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 23: 47-57. PMID 19778266 DOI: 10.1089/Jamp.2009.0759 |
0.373 |
|
| 2010 |
Rytting E, Bur M, Cartier R, Bouyssou T, Wang X, Krüger M, Lehr CM, Kissel T. In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 141: 101-7. PMID 19720096 DOI: 10.1016/J.Jconrel.2009.08.021 |
0.435 |
|
| 2010 |
Lebhardt T, Roesler S, Beck-Broichsitter M, Kissel T. Polymeric nanocarriers for drug delivery to the lung Journal of Drug Delivery Science and Technology. 20: 171-180. DOI: 10.1016/S1773-2247(10)50026-1 |
0.432 |
|
| 2010 |
Agarwal S, Ren L, Kissel T, Bege N. Synthetic Route and Characterization of Main Chain Ester‐Containing Hydrolytically Degradable Poly(N,N‐dimethylaminoethyl methacrylate)‐Based Polycations Macromolecular Chemistry and Physics. 211: 905-915. DOI: 10.1002/Macp.200900579 |
0.365 |
|
| 2009 |
Mintzer MA, Merkel OM, Kissel T, Simanek EE. Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency. New Journal of Chemistry = Nouveau Journal De Chimie. 33: 1918-1925. PMID 19960102 DOI: 10.1039/B908735D |
0.635 |
|
| 2009 |
Merkel OM, Mintzer MA, Sitterberg J, Bakowsky U, Simanek EE, Kissel T. Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity. Bioconjugate Chemistry. 20: 1799-806. PMID 19708683 DOI: 10.1021/Bc900243R |
0.671 |
|
| 2009 |
Nguyen J, Reul R, Betz T, Dayyoub E, Schmehl T, Gessler T, Bakowsky U, Seeger W, Kissel T. Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 140: 47-54. PMID 19666064 DOI: 10.1016/J.Jconrel.2009.07.017 |
0.702 |
|
| 2009 |
Reul R, Nguyen J, Kissel T. Amine-modified hyperbranched polyesters as non-toxic, biodegradable gene delivery systems. Biomaterials. 30: 5815-24. PMID 19615740 DOI: 10.1016/J.Biomaterials.2009.06.057 |
0.73 |
|
| 2009 |
Merkel OM, Beyerle A, Librizzi D, Pfestroff A, Behr TM, Sproat B, Barth PJ, Kissel T. Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance. Molecular Pharmaceutics. 6: 1246-60. PMID 19606864 DOI: 10.1021/Mp900107V |
0.668 |
|
| 2009 |
Kleemann E, Jekel N, Dailey LA, Roesler S, Fink L, Weissmann N, Schermuly R, Gessler T, Schmehl T, Roberts CJ, Seeger W, Kissel T. Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery. Journal of Drug Targeting. 17: 638-51. PMID 19589123 DOI: 10.1080/10611860903106414 |
0.448 |
|
| 2009 |
Trapani A, Sitterberg J, Bakowsky U, Kissel T. The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs. International Journal of Pharmaceutics. 375: 97-106. PMID 19481695 DOI: 10.1016/J.Ijpharm.2009.03.041 |
0.375 |
|
| 2009 |
Merkel OM, Germershaus O, Wada CK, Tarcha PJ, Merdan T, Kissel T. Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine). Bioconjugate Chemistry. 20: 1270-80. PMID 19476331 DOI: 10.1021/Bc9001695 |
0.802 |
|
| 2009 |
Merkel OM, Librizzi D, Pfestroff A, Schurrat T, Buyens K, Sanders NN, De Smedt SC, Béhé M, Kissel T. Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging. Journal of Controlled Release : Official Journal of the Controlled Release Society. 138: 148-59. PMID 19463870 DOI: 10.1016/J.Jconrel.2009.05.016 |
0.661 |
|
| 2009 |
Beyerle A, Höbel S, Czubayko F, Schulz H, Kissel T, Aigner A, Stoeger T. In vitro cytotoxic and immunomodulatory profiling of low molecular weight polyethylenimines for pulmonary application. Toxicology in Vitro : An International Journal Published in Association With Bibra. 23: 500-8. PMID 19444927 DOI: 10.1016/J.Tiv.2009.01.001 |
0.363 |
|
| 2009 |
Jintapattanakit A, Junyaprasert VB, Kissel T. The role of mucoadhesion of trimethyl chitosan and PEGylated trimethyl chitosan nanocomplexes in insulin uptake. Journal of Pharmaceutical Sciences. 98: 4818-30. PMID 19408295 DOI: 10.1002/Jps.21783 |
0.32 |
|
| 2009 |
Malek A, Merkel O, Fink L, Czubayko F, Kissel T, Aigner A. In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes. Toxicology and Applied Pharmacology. 236: 97-108. PMID 19371615 DOI: 10.1016/J.Taap.2009.01.014 |
0.627 |
|
| 2009 |
Merkel OM, Librizzi D, Pfestroff A, Schurrat T, Béhé M, Kissel T. In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure. Bioconjugate Chemistry. 20: 174-82. PMID 19093855 DOI: 10.1021/Bc800408G |
0.598 |
|
| 2009 |
Beck-Broichsitter M, Gauss J, Packhaeuser CB, Lahnstein K, Schmehl T, Seeger W, Kissel T, Gessler T. Pulmonary drug delivery with aerosolizable nanoparticles in an ex vivo lung model. International Journal of Pharmaceutics. 367: 169-78. PMID 18848609 DOI: 10.1016/J.Ijpharm.2008.09.017 |
0.378 |
|
| 2009 |
Packhaeuser CB, Lahnstein K, Sitterberg J, Schmehl T, Gessler T, Bakowsky U, Seeger W, Kissel T. Stabilization of aerosolizable nano-carriers by freeze-drying. Pharmaceutical Research. 26: 129-38. PMID 18841449 DOI: 10.1007/S11095-008-9714-0 |
0.314 |
|
| 2009 |
Cai C, Mao S, Germershaus O, Schaper A, Rytting E, Chen D, Kissel T. Influence of morphology and drug distribution on the release process of FITC-dextran-loaded microspheres prepared with different types of PLGA. Journal of Microencapsulation. 26: 334-45. PMID 18720198 DOI: 10.1080/02652040802354707 |
0.716 |
|
| 2009 |
Agarwal S, Kumar R, Kissel T, Reul R. Synthesis of Degradable Materials Based on Caprolactone and Vinyl Acetate Units Using Radical Chemistry Polymer Journal. 41: 650-660. DOI: 10.1295/Polymj.Pj2009091 |
0.35 |
|
| 2009 |
Liu Y, Nguyen J, Steele T, Merkel O, Kissel T. A new synthesis method and degradation of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymers (hy-PEI-g-PCL-b-mPEG) as potential DNA delivery vectors Polymer. 50: 3895-3904. DOI: 10.1016/J.Polymer.2009.06.043 |
0.775 |
|
| 2008 |
Nguyen J, Xie X, Neu M, Dumitrascu R, Reul R, Sitterberg J, Bakowsky U, Schermuly R, Fink L, Schmehl T, Gessler T, Seeger W, Kissel T. Effects of cell-penetrating peptides and pegylation on transfection efficiency of polyethylenimine in mouse lungs. The Journal of Gene Medicine. 10: 1236-46. PMID 18780309 DOI: 10.1002/Jgm.1255 |
0.651 |
|
| 2008 |
Mei D, Mao S, Sun W, Wang Y, Kissel T. Effect of chitosan structure properties and molecular weight on the intranasal absorption of tetramethylpyrazine phosphate in rats. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 70: 874-81. PMID 18656537 DOI: 10.1016/J.Ejpb.2008.06.031 |
0.344 |
|
| 2008 |
Nguyen J, Steele TW, Merkel O, Reul R, Kissel T. Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 132: 243-51. PMID 18619502 DOI: 10.1016/J.Jconrel.2008.06.010 |
0.769 |
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| 2008 |
Jintapattanakit A, Mao S, Kissel T, Junyaprasert VB. Physicochemical properties and biocompatibility of N-trimethyl chitosan: effect of quaternization and dimethylation. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 70: 563-71. PMID 18602467 DOI: 10.1016/J.Ejpb.2008.06.002 |
0.357 |
|
| 2008 |
Rytting E, Nguyen J, Wang X, Kissel T. Biodegradable polymeric nanocarriers for pulmonary drug delivery. Expert Opinion On Drug Delivery. 5: 629-39. PMID 18532919 DOI: 10.1517/17425247.5.6.629 |
0.669 |
|
| 2008 |
Maretschek S, Greiner A, Kissel T. Electrospun biodegradable nanofiber nonwovens for controlled release of proteins. Journal of Controlled Release : Official Journal of the Controlled Release Society. 127: 180-7. PMID 18314212 DOI: 10.1016/J.Jconrel.2008.01.011 |
0.354 |
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| 2008 |
Sun W, Mao S, Mei D, Kissel T. Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and enoxaparin. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 69: 417-25. PMID 18294825 DOI: 10.1016/J.Ejpb.2008.01.016 |
0.412 |
|
| 2008 |
Unger F, Wittmar M, Morell F, Kissel T. Branched polyesters based on poly[vinyl-3-(dialkylamino)alkylcarbamate-co-vinyl acetate-co-vinyl alcohol]-graft-poly(D,L-lactide-co-glycolide): effects of polymer structure on in vitro degradation behaviour. Biomaterials. 29: 2007-14. PMID 18262641 DOI: 10.1016/J.Biomaterials.2007.12.027 |
0.413 |
|
| 2008 |
Germershaus O, Neu M, Behe M, Kissel T. HER2 targeted polyplexes: The effect of polyplex composition and conjugation chemistry on in vitro and in vivo characteristics Bioconjugate Chemistry. 19: 244-253. PMID 18034452 DOI: 10.1021/Bc700311N |
0.732 |
|
| 2008 |
Germershaus O, Mao S, Sitterberg J, Bakowsky U, Kissel T. Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro. Journal of Controlled Release : Official Journal of the Controlled Release Society. 125: 145-54. PMID 18023906 DOI: 10.1016/J.Jconrel.2007.10.013 |
0.75 |
|
| 2008 |
Cai C, Bakowsky U, Rytting E, Schaper AK, Kissel T. Charged nanoparticles as protein delivery systems: a feasibility study using lysozyme as model protein. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 69: 31-42. PMID 18023160 DOI: 10.1016/J.Ejpb.2007.10.005 |
0.408 |
|
| 2008 |
Beyerle A, Merkel O, Schulz H, Kissel T, Stöger T. Nanohale – Cytotoxic and proinflammatory evaluation of various PEI particles on lung target cells Pneumologie. 62. DOI: 10.1055/S-2008-1074269 |
0.588 |
|
| 2008 |
Nguyen J, Xie X, Neu M, Reul R, Dumitrascu R, Schermuly R, Fink L, Schmehl T, Gessler T, Seeger W, Kissel T. Nanohale – Nicht-virale Vektoren für den pulmonalen Gentransfer Pneumologie. 62. DOI: 10.1055/S-2008-1074268 |
0.605 |
|
| 2008 |
Malek A, Aigner A, Merkel O, Czubayko F, Kissel T. Nanohale – PEI(-PEG)/siRNA nanoscale complexes, inducing RNA interference (RNAi), for systemic and local siRNA delivery to the lung Pneumologie. 62. DOI: 10.1055/S-2008-1074267 |
0.612 |
|
| 2008 |
Wang X, Xie X, Cai C, Rytting E, Steele T, Kissel T. Biodegradable branched polyesters poly(vinyl sulfonate-covinyl alcohol)-graft poly(D,L-lactic-coglycolic acid) as a negatively charged polyelectrolyte platform for drug delivery: Synthesis and characterization Macromolecules. 41: 2791-2799. DOI: 10.1021/Ma702705S |
0.42 |
|
| 2007 |
Neu M, Germershaus O, Behe M, Kissel T. Bioreversibly crosslinked polyplexes of PEI and high molecular weight PEG show extended circulation times in vivo Journal of Controlled Release. 124: 69-80. PMID 17897749 DOI: 10.1016/J.Jconrel.2007.08.009 |
0.754 |
|
| 2007 |
Mao S, Augsten C, Mäder K, Kissel T. Characterization of chitosan and its derivatives using asymmetrical flow field-flow-fractionation: a comparison with traditional methods. Journal of Pharmaceutical and Biomedical Analysis. 45: 736-41. PMID 17890038 DOI: 10.1016/J.Jpba.2007.08.012 |
0.313 |
|
| 2007 |
Mao S, Shi Y, Li L, Xu J, Schaper A, Kissel T. Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 68: 214-23. PMID 17651954 DOI: 10.1016/J.Ejpb.2007.06.008 |
0.387 |
|
| 2007 |
Jintapattanakit A, Junyaprasert VB, Mao S, Sitterberg J, Bakowsky U, Kissel T. Peroral delivery of insulin using chitosan derivatives: a comparative study of polyelectrolyte nanocomplexes and nanoparticles. International Journal of Pharmaceutics. 342: 240-9. PMID 17597316 DOI: 10.1016/J.Ijpharm.2007.05.015 |
0.36 |
|
| 2007 |
Westedt U, Kalinowski M, Wittmar M, Merdan T, Unger F, Fuchs J, Schäller S, Bakowsky U, Kissel T. Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment. Journal of Controlled Release : Official Journal of the Controlled Release Society. 119: 41-51. PMID 17346845 DOI: 10.1016/J.Jconrel.2007.01.009 |
0.405 |
|
| 2007 |
Neu M, Germershaus O, Mao S, Voigt KH, Behe M, Kissel T. Crosslinked nanocarriers based upon poly(ethylene imine) for systemic plasmid delivery: in vitro characterization and in vivo studies in mice. Journal of Controlled Release : Official Journal of the Controlled Release Society. 118: 370-80. PMID 17316863 DOI: 10.1016/J.Jconrel.2007.01.007 |
0.74 |
|
| 2007 |
Unger F, Westedt U, Hanefeld P, Wombacher R, Zimmermann S, Greiner A, Ausborn M, Kissel T. Poly(ethylene carbonate): A thermoelastic and biodegradable biomaterial for drug eluting stent coatings? Journal of Controlled Release. 117: 312-321. PMID 17207879 DOI: 10.1016/J.Jconrel.2006.11.003 |
0.332 |
|
| 2007 |
Mao S, Xu J, Cai C, Germershaus O, Schaper A, Kissel T. Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres. International Journal of Pharmaceutics. 334: 137-48. PMID 17196348 DOI: 10.1016/J.Ijpharm.2006.10.036 |
0.724 |
|
| 2007 |
Unger F, Wittmar M, Kissel T. Branched polyesters based on poly[vinyl-3-(dialkylamino)alkylcarbamate-co-vinyl acetate-co-vinyl alcohol]-graft-poly(d,l-lactide-co-glycolide): effects of polymer structure on cytotoxicity. Biomaterials. 28: 1610-1619. PMID 17196250 DOI: 10.1016/J.Biomaterials.2006.12.002 |
0.43 |
|
| 2007 |
Simon M, Behrens I, Dailey LA, Wittmar M, Kissel T. Nanosized insulin-complexes based on biodegradable amine-modified graft polyesters poly[vinyl-3-(diethylamino)-propylcarbamate-co-(vinyl acetate)-co-(vinyl alcohol)]-graft-poly(l-lactic acid): Protection against enzymatic degradation, interaction with Caco-2 cell monolayers, peptide transport and cytotoxicity European Journal of Pharmaceutics and Biopharmaceutics. 66: 165-172. PMID 17150341 DOI: 10.1016/J.Ejpb.2006.10.009 |
0.364 |
|
| 2006 |
Neu M, Sitterberg J, Bakowsky U, Kissel T. Stabilized nanocarriers for plasmids based upon cross-linked poly(ethylene imine) Biomacromolecules. 7: 3428-3438. PMID 17154471 DOI: 10.1021/Bm060788Z |
0.366 |
|
| 2006 |
Anabousi S, Kleemann E, Bakowsky U, Kissel T, Schmehl T, Gessler T, Seeger W, Lehr CM, Ehrhardt C. Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant. Journal of Nanoscience and Nanotechnology. 6: 3010-6. PMID 17048512 DOI: 10.1166/Jnn.2006.461 |
0.345 |
|
| 2006 |
Mao S, Neu M, Germershaus O, Merkel O, Sitterberg J, Bakowsky U, Kissel T. Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes. Bioconjugate Chemistry. 17: 1209-18. PMID 16984130 DOI: 10.1021/Bc060129J |
0.785 |
|
| 2006 |
Germershaus O, Merdan T, Bakowsky U, Behe M, Kissel T. Trastuzumab-polyethylenimine-polyethylene glycol conjugates for targeting Her2-expressing tumors. Bioconjugate Chemistry. 17: 1190-9. PMID 16984128 DOI: 10.1021/Bc0601119 |
0.744 |
|
| 2006 |
Hanefeld P, Westedt U, Wombacher R, Kissel T, Schaper A, Wendorff JH, Greiner A. Coating of poly(p-xylylene) by PLA-PEO-PLA triblock copolymers with excellent polymer-polymer adhesion for stent applications. Biomacromolecules. 7: 2086-90. PMID 16827574 DOI: 10.1021/Bm050642K |
0.362 |
|
| 2006 |
Schnieders J, Gbureck U, Thull R, Kissel T. Controlled release of gentamicin from calcium phosphate-poly(lactic acid-co-glycolic acid) composite bone cement. Biomaterials. 27: 4239-49. PMID 16620958 DOI: 10.1016/J.Biomaterials.2006.03.032 |
0.344 |
|
| 2006 |
Mao S, Bakowsky U, Jintapattanakit A, Kissel T. Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin. Journal of Pharmaceutical Sciences. 95: 1035-48. PMID 16565978 DOI: 10.1002/Jps.20520 |
0.359 |
|
| 2006 |
Dailey LA, Jekel N, Fink L, Gessler T, Schmehl T, Wittmar M, Kissel T, Seeger W. Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung. Toxicology and Applied Pharmacology. 215: 100-108. PMID 16551473 DOI: 10.1016/J.Taap.2006.01.016 |
0.395 |
|
| 2006 |
Oster CG, Wittmar M, Bakowsky U, Kissel T. DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method. Journal of Controlled Release : Official Journal of the Controlled Release Society. 111: 371-81. PMID 16499988 DOI: 10.1016/J.Jconrel.2005.12.004 |
0.394 |
|
| 2006 |
Westedt U, Wittmar M, Hellwig M, Hanefeld P, Greiner A, Schaper AK, Kissel T. Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings. Journal of Controlled Release : Official Journal of the Controlled Release Society. 111: 235-46. PMID 16466824 DOI: 10.1016/J.Jconrel.2005.12.012 |
0.376 |
|
| 2006 |
Wittmar M, Unger aF, Kissel T. Biodegradable Brushlike Branched Polyesters Containing a Charge-Modified Poly(vinyl alcohol) Backbone as a Platform for Drug Delivery Systems: Synthesis and Characterization Macromolecules. 39: 1417-1424. DOI: 10.1021/Ma051837N |
0.41 |
|
| 2005 |
Dailey LA, Kissel T. New poly(lactic-co-glycolic acid) derivatives: Modular polymers with tailored properties. Drug Discovery Today. Technologies. 2: 7-13. PMID 24981749 DOI: 10.1016/J.Ddtec.2005.05.017 |
0.426 |
|
| 2005 |
Kleemann E, Neu M, Jekel N, Fink L, Schmehl T, Gessler T, Seeger W, Kissel T. Nano-carriers for DNA delivery to the lung based upon a TAT-derived peptide covalently coupled to PEG-PEI. Journal of Controlled Release. 109: 299-316. PMID 16298009 DOI: 10.1016/J.Jconrel.2005.09.036 |
0.401 |
|
| 2005 |
Wittmar M, Ellis JS, Morell F, Unger F, Schumacher JC, Roberts CJ, Tendler SJ, Davies MC, Kissel T. Biophysical and transfection studies of an amine-modified poly(vinyl alcohol) for gene delivery. Bioconjugate Chemistry. 16: 1390-8. PMID 16287235 DOI: 10.1021/Bc0500995 |
0.439 |
|
| 2005 |
Mao S, Germershaus O, Fischer D, Linn T, Schnepf R, Kissel T. Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells. Pharmaceutical Research. 22: 2058-68. PMID 16170693 DOI: 10.1007/S11095-005-8175-Y |
0.761 |
|
| 2005 |
Simon M, Wittmar M, Kissel T, Linn T. Insulin containing nanocomplexes formed by self-assembly from biodegradable amine-modified poly(vinyl alcohol)-graft-poly(l-lactide): Bioavailability and nasal tolerability in rats Pharmaceutical Research. 22: 1879-1886. PMID 16132341 DOI: 10.1007/S11095-005-7676-Z |
0.336 |
|
| 2005 |
Merdan T, Kunath K, Petersen H, Bakowsky U, Voigt KH, Kopecek J, Kissel T. PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice. Bioconjugate Chemistry. 16: 785-92. PMID 16029019 DOI: 10.1021/Bc049743Q |
0.42 |
|
| 2005 |
Neu M, Fischer D, Kissel T. Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives Journal of Gene Medicine. 7: 992-1009. PMID 15920783 DOI: 10.1002/Jgm.773 |
0.689 |
|
| 2005 |
Mao S, Shuai X, Unger F, Wittmar M, Xie X, Kissel T. Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers. Biomaterials. 26: 6343-56. PMID 15913769 DOI: 10.1016/J.Biomaterials.2005.03.036 |
0.455 |
|
| 2005 |
Oster CG, Kim N, Grode L, Barbu-Tudoran L, Schaper AK, Kaufmann SHE, Kissel T. Cationic microparticles consisting of poly(lactide-co-glycolide) and polyethylenimine as carriers systems for parental DNA vaccination Journal of Controlled Release. 104: 359-377. PMID 15907586 DOI: 10.1016/J.Jconrel.2005.02.004 |
0.376 |
|
| 2005 |
Zeng J, Aigner A, Czubayko F, Kissel T, Wendorff JH, Greiner A. Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. Biomacromolecules. 6: 1484-8. PMID 15877368 DOI: 10.1021/Bm0492576 |
0.339 |
|
| 2005 |
Shuai X, Merdan T, Unger F, Kissel T. Supramolecular gene delivery vectors showing enhanced transgene expression and good biocompatibility Bioconjugate Chemistry. 16: 322-329. PMID 15769085 DOI: 10.1021/Bc0498471 |
0.444 |
|
| 2005 |
Dailey LA, Wittmar M, Kissel T. The role of branched polyesters and their modifications in the development of modern drug delivery vehicles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 101: 137-49. PMID 15588900 DOI: 10.1016/J.Jconrel.2004.09.003 |
0.424 |
|
| 2005 |
Dailey LA, Kleemann E, Merdan T, Petersen H, Schmehl T, Gessler T, Hänze J, Seeger W, Kissel T. Modified polyethylenimines as non viral gene delivery systems for aerosol therapy: effects of nebulization on cellular uptake and transfection efficiency. Journal of Controlled Release : Official Journal of the Controlled Release Society. 100: 425-36. PMID 15567507 DOI: 10.1016/J.Jconrel.2004.08.031 |
0.402 |
|
| 2005 |
Kissel T. Lipospheres in Drug Targets and Delivery, Claudio Nastruzzi (Ed.). CRC Press, Boca Raton, FL (2005), 208 pp €169,95, ISBN: 0-8493-1692-8 European Journal of Pharmaceutics and Biopharmaceutics. 61. DOI: 10.1016/J.Ejpb.2005.04.001 |
0.3 |
|
| 2004 |
Kleemann E, Dailey LA, Abdelhady HG, Gessler T, Schmehl T, Roberts CJ, Davies MC, Seeger W, Kissel T. Modified polyethylenimines as non-viral gene delivery systems for aerosol gene therapy: investigations of the complex structure and stability during air-jet and ultrasonic nebulization. Journal of Controlled Release. 100: 437-450. PMID 15567508 DOI: 10.1016/J.Jconrel.2004.09.005 |
0.382 |
|
| 2004 |
Fischer D, Osburg B, Petersen H, Kissel T, Bickel U. Effect of poly(ethylene imine) molecular weight and pegylation on organ distribution and pharmacokinetics of polyplexes with oligodeoxynucleotides in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 983-92. PMID 15319340 |
0.612 |
|
| 2004 |
Packhaeuser CB, Schnieders J, Oster CG, Kissel T. In situ forming parenteral drug delivery systems: an overview European Journal of Pharmaceutics and Biopharmaceutics. 58: 445-455. PMID 15296966 DOI: 10.1016/J.Ejpb.2004.03.003 |
0.335 |
|
| 2004 |
Mao S, Shuai X, Unger F, Simon M, Bi D, Kissel T. The depolymerization of chitosan: Effects on physicochemical and biological properties International Journal of Pharmaceutics. 281: 45-54. PMID 15288342 DOI: 10.1016/J.Ijpharm.2004.05.019 |
0.361 |
|
| 2004 |
Fischer D, Dautzenberg H, Kunath K, Kissel T. Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and in vitro activity. International Journal of Pharmaceutics. 280: 253-69. PMID 15265564 DOI: 10.1016/J.Ijpharm.2004.05.018 |
0.671 |
|
| 2004 |
Brus C, Petersen H, Aigner A, Czubayko F, Kissel T. Physicochemical and biological characterization of polyethylenimine-graft-poly(ethylene glycol) block copolymers as a delivery system for oligonucleotides and ribozymes. Bioconjugate Chemistry. 15: 677-684. PMID 15264853 DOI: 10.1021/Bc034160M |
0.431 |
|
| 2004 |
Schliecker G, Schmidt C, Fuchs S, Kissel T. Characterization and in vitro degradation of poly(2,3-(1,4-diethyl tartrate)-co-2,3-isopropyliden tartrate). Journal of Controlled Release. 98: 11-23. PMID 15245885 DOI: 10.1016/J.Jconrel.2004.03.035 |
0.4 |
|
| 2004 |
Oster CG, Wittmar M, Unger F, Barbu-Tudoran L, Schaper AK, Kissel T. Design of amine-modified graft polyesters for effective gene delivery using DNA-loaded nanoparticles. Pharmaceutical Research. 21: 927-931. PMID 15212155 DOI: 10.1023/B:Pham.0000029279.50733.55 |
0.377 |
|
| 2004 |
Westedt U, Barbu-Tudoran L, Schaper AK, Kalinowski M, Alfke H, Kissel T. Effects of different application parameters on penetration characteristics and arterial vessel wall integrity after local nanoparticle delivery using a porous balloon catheter European Journal of Pharmaceutics and Biopharmaceutics. 58: 161-168. PMID 15207550 DOI: 10.1016/J.Ejpb.2004.03.009 |
0.343 |
|
| 2004 |
Winzenburg G, Schmidt C, Fuchs S, Kissel T. Biodegradable polymers and their potential use in parenteral veterinary drug delivery systems. Advanced Drug Delivery Reviews. 56: 1453-1466. PMID 15191792 DOI: 10.1016/J.Addr.2004.02.008 |
0.354 |
|
| 2004 |
Shuai X, Merdan T, Schaper AK, Xi F, Kissel T. Core-cross-linked polymeric micelles as paclitaxel carriers Bioconjugate Chemistry. 15: 441-448. PMID 15149170 DOI: 10.1021/Bc034113U |
0.398 |
|
| 2004 |
Brus C, Petersen H, Aigner A, Czubayko F, Kissel T. Efficiency of polyethylenimines and polyethylenimine-graft-poly (ethylene glycol) block copolymers to protect oligonucleotides against enzymatic degradation. European Journal of Pharmaceutics and Biopharmaceutics. 57: 427-430. PMID 15093589 DOI: 10.1016/J.Ejpb.2004.02.004 |
0.448 |
|
| 2004 |
Brus C, Kleemann E, Aigner A, Czubayko F, Kissel T. Stabilization of oligonucleotide–polyethylenimine complexes by freeze-drying: physicochemical and biological characterization Journal of Controlled Release. 95: 119-131. PMID 15013239 DOI: 10.1016/J.Jconrel.2003.10.021 |
0.343 |
|
| 2004 |
Vila A, Sánchez A, Janes K, Behrens I, Kissel T, Vila Jato JL, Alonso MJ. Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 57: 123-31. PMID 14729088 DOI: 10.1016/J.Ejpb.2003.09.006 |
0.342 |
|
| 2004 |
Schliecker G, Schmidt C, Fuchs S, Ehinger A, Sandow J, Kissel T. In vitro and in vivo correlation of buserelin release from biodegradable implants using statistical moment analysis Journal of Controlled Release. 94: 25-37. PMID 14684269 DOI: 10.1016/J.Jconrel.2003.09.003 |
0.332 |
|
| 2003 |
Dailey LA, Kleemann E, Wittmar M, Gessler T, Schmehl T, Roberts C, Seeger W, Kissel T. Surfactant-free, biodegradable nanoparticles for aerosol therapy based on the branched polyesters, DEAPA-PVAL-g-PLGA. Pharmaceutical Research. 20: 2011-2020. PMID 14725368 DOI: 10.1023/B:Pham.0000008051.94834.10 |
0.358 |
|
| 2003 |
Dadsetan M, Christenson EM, Unger F, Ausborn M, Kissel T, Hiltner A, Anderson JM. In vivo biocompatibility and biodegradation of poly(ethylene carbonate). Journal of Controlled Release : Official Journal of the Controlled Release Society. 93: 259-70. PMID 14644576 DOI: 10.1016/J.Jconrel.2003.08.010 |
0.31 |
|
| 2003 |
Schliecker G, Schmidt C, Fuchs S, Wombacher R, Kissel T. Hydrolytic degradation of poly(lactide-co-glycolide) films: effect of oligomers on degradation rate and crystallinity. International Journal of Pharmaceutics. 266: 39-49. PMID 14559392 DOI: 10.1016/S0378-5173(03)00379-X |
0.306 |
|
| 2003 |
Merdan T, Callahan J, Petersen H, Kunath K, Bakowsky U, Kopecková P, Kissel T, Kopecek J. Pegylated polyethylenimine-Fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells. Bioconjugate Chemistry. 14: 989-96. PMID 13129403 DOI: 10.1021/Bc0340767 |
0.404 |
|
| 2003 |
Kunath K, Merdan T, Hegener O, Häberlein H, Kissel T. Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. Journal of Gene Medicine. 5: 588-599. PMID 12825198 DOI: 10.1002/Jgm.382 |
0.442 |
|
| 2003 |
Schliecker G, Schmidt C, Fuchs S, Kissel T. Characterization of a homologous series of D,L-lactic acid oligomers; a mechanistic study on the degradation kinetics in vitro. Biomaterials. 24: 3835-44. PMID 12818556 DOI: 10.1016/S0142-9612(03)00243-6 |
0.332 |
|
| 2003 |
Kunath K, von Harpe A, Fischer D, Petersen H, Bickel U, Voigt K, Kissel T. Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 89: 113-25. PMID 12695067 DOI: 10.1016/S0168-3659(03)00076-2 |
0.665 |
|
| 2003 |
Kunath K, von Harpe A, Fischer D, Kissel T. Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency. Journal of Controlled Release : Official Journal of the Controlled Release Society. 88: 159-72. PMID 12586513 DOI: 10.1016/S0168-3659(02)00458-3 |
0.676 |
|
| 2003 |
Fischer D, Li Y, Ahlemeyer B, Krieglstein J, Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials. 24: 1121-31. PMID 12527253 DOI: 10.1016/S0142-9612(02)00445-3 |
0.68 |
|
| 2003 |
Dailey LA, Schmehl T, Gessler T, Wittmar M, Grimminger F, Seeger W, Kissel T. Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features. Journal of Controlled Release. 86: 131-144. PMID 12490379 DOI: 10.1016/S0168-3659(02)00370-X |
0.327 |
|
| 2003 |
Shuai X, Merdan T, Unger F, Wittmar M, Kissel T. Novel biodegradable ternary copolymers hy-PEI-g-PCL-b-PEG: Synthesis, characterization, and potential as efficient nonviral gene delivery vectors Macromolecules. 36: 5751-5759. DOI: 10.1021/Ma034390W |
0.488 |
|
| 2002 |
Westedt U, Barbu-Tudoran L, Schaper AK, Kalinowski M, Alfke H, Kissel T. Deposition of nanoparticles in the arterial vessel by porous balloon catheters: localization by confocal laser scanning microscopy and transmission electron microscopy. Aaps Pharmsci. 4: 206-211. PMID 12646012 DOI: 10.1208/Ps040441 |
0.331 |
|
| 2002 |
Brus C, Santi P, Colombo P, Kissel T. Distribution and quantification of polyethylenimine oligodeoxynucleotide complexes in human skin after iontophoretic delivery using confocal scanning laser microscopy Journal of Controlled Release. 84: 171-181. PMID 12468220 DOI: 10.1016/S0168-3659(02)00295-X |
0.323 |
|
| 2002 |
Eigner A, Fischer D, Merdan T, Brus C, Kissel T, Czubayko F. Delivery of unmodified bioactive ribozymes by an RNA stabilizing polyethylenimine LMW PEI efficiently down regulates gene expression Gene Therapy. 9: 1700-1707. PMID 12457284 DOI: 10.1038/Sj.Gt.3301839 |
0.321 |
|
| 2002 |
Behrens I, Pena AIV, Alonso MJ, Kissel T. Comparative Uptake Studies of Bioadhesive and Non-Bioadhesive Nanoparticles in Human Intestinal Cell Lines and Rats: The Effect of Mucus on Particle Adsorption and Transport Pharmaceutical Research. 19: 1185-1193. PMID 12240945 DOI: 10.1023/A:1019854327540 |
0.311 |
|
| 2002 |
Jung T, Kamm W, Breitenbach A, Klebe G, Kissel T. Loading of tetanus toxoid to biodegradable nanoparticles from branched poly(sulfobutyl-polyvinyl alcohol)-g-(lactide-co-glycolide) nanoparticles by protein adsorption: a mechanistic study. Pharmaceutical Research. 19: 1105-1113. PMID 12240935 DOI: 10.1023/A:1019833822997 |
0.306 |
|
| 2002 |
Fischer D, von Harpe A, Kunath K, Petersen H, Li Y, Kissel T. Copolymers of ethylene imine and N-(2-hydroxyethyl)-ethylene imine as tools to study effects of polymer structure on physicochemical and biological properties of DNA complexes. Bioconjugate Chemistry. 13: 1124-33. PMID 12236795 DOI: 10.1021/Bc025550W |
0.702 |
|
| 2002 |
Petersen H, Kunath K, Martin AL, Stolnik S, Roberts CJ, Davies MC, Kissel T. Star-shaped poly(ethylene glycol)-block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines. Biomacromolecules. 3: 926-936. PMID 12217037 DOI: 10.1021/Bm025539Z |
0.367 |
|
| 2002 |
Merdan T, Kopecek J, Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Advanced Drug Delivery Reviews. 54: 715-58. PMID 12204600 DOI: 10.1016/S0169-409X(02)00046-7 |
0.361 |
|
| 2002 |
Kunath K, von Harpe A, Petersen H, Fischer D, Voigt K, Kissel T, Bickel U. The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kappaB decoy in mice. Pharmaceutical Research. 19: 810-7. PMID 12134951 DOI: 10.1023/A:1016152831963 |
0.646 |
|
| 2002 |
Petersen H, Fechner PM, Martin AL, Kunath K, Stolnik S, Roberts CJ, Fischer D, Davies MC, Kissel T. Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. Bioconjugate Chemistry. 13: 845-54. PMID 12121141 DOI: 10.1021/Bc025529V |
0.694 |
|
| 2002 |
Petersen H, Merdan T, Kunath K, Fischer D, Kissel T. Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery. Bioconjugate Chemistry. 13: 812-21. PMID 12121137 DOI: 10.1021/Bc0255135 |
0.682 |
|
| 2002 |
Merdan T, Kunath K, Fischer D, Kopecek J, Kissel T. Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments. Pharmaceutical Research. 19: 140-6. PMID 11883640 DOI: 10.1023/A:1014212630566 |
0.62 |
|
| 2002 |
Jung T, Koneberg R, Hungerer KD, Kissel T. Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblock-copolymers: immune response in mice. International Journal of Pharmaceutics. 234: 75-90. PMID 11839439 DOI: 10.1016/S0378-5173(01)00957-7 |
0.322 |
|
| 2002 |
Kissel T, Li Y, Unger F. AbA-triblock copolymers from biodegradable polyester A-blocks and hydrophilic poly(ethylene oxide) B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins Advanced Drug Delivery Reviews. 54: 99-134. PMID 11755708 DOI: 10.1016/S0169-409X(01)00244-7 |
0.406 |
|
| 2002 |
Petersen H, Martin AL, Stolnik S, Roberts CJ, Davies MC, Kissel T. The macrostopper route: A new synthesis concept leading exclusively to diblock copolymers with enhanced DNA condensation potential Macromolecules. 35: 9854-9856. DOI: 10.1021/Ma025625R |
0.315 |
|
| 2002 |
Petersen H, Fechner PM, Fischer D, Kissel T. Synthesis, Characterization, and Biocompatibility of Polyethylenimine-graft-poly(ethylene glycol) Block Copolymers Macromolecules. 35: 6867-6874. DOI: 10.1021/Ma012060A |
0.68 |
|
| 2001 |
Fischer D, Bieber T, Brüsselbach S, Elsässer H, Kissel T. Cationized human serum albumin as a non-viral vector system for gene delivery? Characterization of complex formation with plasmid DNA and transfection efficiency. International Journal of Pharmaceutics. 225: 97-111. PMID 11489558 DOI: 10.1016/S0378-5173(01)00765-7 |
0.675 |
|
| 2001 |
Jung T, Kamm W, Breitenbach A, Hungerer K, Hundt E, Kissel T. Tetanus toxoid loaded nanoparticles from sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide): evaluation of antibody response after oral and nasal application in mice. Pharmaceutical Research. 18: 352-360. PMID 11442276 DOI: 10.1023/A:1011063232257 |
0.316 |
|
| 2001 |
Fischer D, Kissel T. Histochemical characterization of primary capillary endothelial cells from porcine brains using monoclonal antibodies and fluorescein isothiocyanate-labelled lectins: implications for drug delivery European Journal of Pharmaceutics and Biopharmaceutics. 52: 1-11. PMID 11438418 DOI: 10.1016/S0939-6411(01)00159-X |
0.602 |
|
| 2001 |
Witt C, Kissel T. Morphological characterization of microspheres, films and implants prepared from poly(lactide-co-glycolide) and ABA triblock copolymers: is the erosion controlled by degradation, swelling or diffusion? European Journal of Pharmaceutics and Biopharmaceutics. 51: 171-181. PMID 11343880 DOI: 10.1016/S0939-6411(01)00130-8 |
0.34 |
|
| 2001 |
Pistel KF, Breitenbach A, Zange-Volland R, Kissel T. Brush-like branched biodegradable polyesters, part III. Protein release from microspheres of poly(vinyl alcohol)-graft-poly(D,L-lactic-co-glycolic acid). Journal of Controlled Release. 73: 7-20. PMID 11337055 DOI: 10.1016/S0168-3659(01)00231-0 |
0.435 |
|
| 2001 |
De Jaeghere F, Allémann E, Feijen J, Kissel T, Doelker E, Gurny R. Freeze-drying and lyopreservation of diblock and triblock poly(lactic acid)-poly(ethylene oxide) (PLA-PEO) copolymer nanoparticles. Pharmaceutical Development and Technology. 5: 473-83. PMID 11109247 DOI: 10.1081/Pdt-100102031 |
0.365 |
|
| 2001 |
von Harpe A, Petersen H, Li Y, Kissel T. Characterization of commercially available and synthesized polyethylenimines for gene delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 69: 309-22. PMID 11064137 DOI: 10.1016/S0168-3659(00)00317-5 |
0.4 |
|
| 2001 |
Kissel T. Submicron Emulsions in Drug Targeting and Delivery Journal of Controlled Release. 75: 227-228. DOI: 10.1016/S0168-3659(01)00384-4 |
0.321 |
|
| 2000 |
Ahlemeyer B, Fischer D, Kissel T, Krieglstein J. Staurosporine-induced apoptosis in cultured chick embryonic neurons is reduced by polyethylenimine of low molecular weight used as a coating substrate. Neuroscience Research. 37: 245-53. PMID 10958973 DOI: 10.1016/S0168-0102(00)00128-0 |
0.583 |
|
| 2000 |
De Jaeghere F, Allemann E, Feijen J, Kissel T, Doelker E, Gurny R. Cellular uptake of PEO surface-modified nanoparticles: evaluation of nanoparticles made of PLA:PEO diblock and triblock copolymers. Journal of Drug Targeting. 8: 143-53. PMID 10938524 DOI: 10.3109/10611860008996860 |
0.384 |
|
| 2000 |
Jung T, Kamm W, Breitenbach A, Kaiserling E, Xiao JX, Kissel T. Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake? European Journal of Pharmaceutics and Biopharmaceutics. 50: 147-160. PMID 10840198 DOI: 10.1016/S0939-6411(00)00084-9 |
0.408 |
|
| 2000 |
Jung T, Breitenbach A, Kissel T. Sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres. Journal of Controlled Release. 67: 157-169. PMID 10825550 DOI: 10.1016/S0168-3659(00)00201-7 |
0.362 |
|
| 2000 |
Kamm W, Jonczyk A, Jung T, Luckenbach G, Raddatz P, Kissel T. Evaluation of absorption enhancement for a potent cyclopeptidic ανβ3-antagonist in a human intestinal cell line (Caco-2) European Journal of Pharmaceutical Sciences. 10: 205-214. PMID 10767598 DOI: 10.1016/S0928-0987(99)00092-5 |
0.342 |
|
| 2000 |
Witt C, Mäder K, Kissel T. The degradation, swelling and erosion properties of biodegradable implants prepared by extrusion or compression moulding of poly(lactide-co-glycolide) and ABA triblock copolymers. Biomaterials. 21: 931-938. PMID 10735470 DOI: 10.1016/S0142-9612(99)00262-8 |
0.417 |
|
| 2000 |
Breitenbach A, Li YX, Kissel T. Branched biodegradable polyesters for parenteral drug delivery systems. Journal of Controlled Release. 64: 167-178. PMID 10640655 DOI: 10.1016/S0168-3659(99)00134-0 |
0.437 |
|
| 2000 |
Breitenbach A, Mohr D, Kissel T. Biodegradable semi-crystalline comb polyesters influence the microsphere production by means of a supercritical fluid extraction technique (ASES). Journal of Controlled Release : Official Journal of the Controlled Release Society. 63: 53-68. PMID 10640580 DOI: 10.1016/S0168-3659(99)00173-X |
0.381 |
|
| 2000 |
Breitenbach A, Pistel KF, Kissel T. Biodegradable comb polyesters. Part II. Erosion and release properties of poly(vinyl alcohol)-g-poly(lactic-co-glycolic acid) Polymer. 41: 4781-4792. DOI: 10.1016/S0032-3861(99)00710-7 |
0.419 |
|
| 1999 |
Mohr D, Wolff M, Kissel T. Gamma irradiation for terminal sterilization of 17beta-estradiol loaded poly-(D,L-lactide-co-glycolide) microparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 61: 203-17. PMID 10469916 DOI: 10.1016/S0168-3659(99)00118-2 |
0.388 |
|
| 1999 |
Fischer D, Bieber T, Li Y, Elsässer H, Kissel T. A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity Pharmaceutical Research. 16: 1273-1279. PMID 10468031 DOI: 10.1023/A:1014861900478 |
0.658 |
|
| 1999 |
Bittner B, Witt C, Mäder K, Kissel T. Degradation and protein release properties of microspheres prepared from biodegradable poly(lactide-co-glycolide) and ABA triblock copolymers: influence of buffer media on polymer erosion and bovine serum albumin release. Journal of Controlled Release. 60: 297-309. PMID 10425335 DOI: 10.1016/S0168-3659(99)00085-1 |
0.42 |
|
| 1999 |
Pistel KF, Bittner B, Koll H, Winter G, Kissel T. Biodegradable recombinant human erythropoietin loaded microspheres prepared from linear and star-branched block copolymers: influence of encapsulation technique and polymer composition on particle characteristics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 59: 309-25. PMID 10332063 DOI: 10.1016/S0168-3659(99)00008-5 |
0.423 |
|
| 1999 |
Bittner B, Mäder K, Kroll C, Borchert H-, Kissel T. Tetracycline-HCl-loaded poly(dl-lactide-co-glycolide) microspheres prepared by a spray drying technique: influence of γ-irradiation on radical formation and polymer degradation Journal of Controlled Release. 59: 23-32. PMID 10210719 DOI: 10.1016/S0168-3659(98)00170-9 |
0.378 |
|
| 1999 |
Graulich W, Nettelbeck DM, Fischer D, Kissel T, Müller R. Cell type specificity of the human endoglin promoter Gene. 227: 55-62. PMID 9931433 DOI: 10.1016/S0378-1119(98)00585-X |
0.607 |
|
| 1999 |
Schäfer O, Brink-Spalink F, Smarsly B, Schmidt C, Wendorff JH, Witt C, Kissel T, Greiner A. Synthesis and properties ofω-phenylalkyl-substituted poly(p-xylylene)s prepared by base-induced 1,6-dehydrohalogenation Macromolecular Chemistry and Physics. 200: 1942-1949. DOI: 10.1002/(Sici)1521-3935(19990801)200:8<1942::Aid-Macp1942>3.0.Co;2-H |
0.317 |
|
| 1998 |
Roser M, Fischer D, Kissel T. Surface-modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats European Journal of Pharmaceutics and Biopharmaceutics. 46: 255-263. PMID 9885296 DOI: 10.1016/S0939-6411(98)00038-1 |
0.633 |
|
| 1998 |
Zange R, Li Y, Kissel T. Biocompatibility testing of ABA triblock copolymers consisting of poly(L-lactic-co-glycolic acid) A blocks attached to a central poly(ethylene oxide) B block under in vitro conditions using different L929 mouse fibroblasts cell culture models. Journal of Controlled Release. 56: 249-258. PMID 9801448 DOI: 10.1016/S0168-3659(98)00093-5 |
0.408 |
|
| 1998 |
Kriwet B, Walter E, Kissel T. Synthesis of bioadhesive poly(acrylic acid) nano- and microparticles using an inverse emulsion polymerization method for the entrapment of hydrophilic drug candidates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 56: 149-58. PMID 9801438 DOI: 10.1016/S0168-3659(98)00078-9 |
0.398 |
|
| 1998 |
Morlock M, Kissel T, Li YX, Koll H, Winter G. Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: protein stabilization and in-vitro release properties. Journal of Controlled Release : Official Journal of the Controlled Release Society. 56: 105-15. PMID 9801434 DOI: 10.1016/S0168-3659(98)00070-4 |
0.419 |
|
| 1998 |
Lück M, Pistel K, Li Y, Blunk T, Müller RH, Kissel T. Plasma protein adsorption on biodegradable microspheres consisting of poly(d,l-lactide-co-glycolide), poly(l-lactide) or ABA triblock copolymers containing poly(oxyethylene): Influence of production method and polymer composition Journal of Controlled Release. 55: 107-120. PMID 9795026 DOI: 10.1016/S0168-3659(98)00030-3 |
0.348 |
|
| 1998 |
Kissel T, Werner U. Nasal delivery of peptides: an in vitro cell culture model for the investigation of transport and metabolism in human nasal epithelium Journal of Controlled Release. 53: 195-203. PMID 9741927 DOI: 10.1016/S0168-3659(97)00253-8 |
0.323 |
|
| 1998 |
Bittner B, Morlock M, Koll H, Winter G, Kissel T. Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co-glycolide) microspheres: influence of the encapsulation technique and polymer purity on microsphere characteristics. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fã¼R Pharmazeutische Verfahrenstechnik E.V. 45: 295-305. PMID 9653634 DOI: 10.1016/S0939-6411(98)00012-5 |
0.375 |
|
| 1998 |
Bittner B, Ronneberger B, Zange R, Volland C, Anderson JM, Kissel T. Bovine serum albumin loaded poly(lactide-co-glycolide) microspheres: the influence of polymer purity on particle characteristics. Journal of Microencapsulation. 15: 495-514. PMID 9651871 DOI: 10.3109/02652049809006876 |
0.426 |
|
| 1998 |
Mäder K, Bittner B, Li Y, Wohlauf W, Kissel T. Monitoring microviscosity and microacidity of the albumin microenvironment inside degrading microparticles from poly(lactide-co-glycolide) (PLG) or ABA-triblock polymers containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethyleneoxide) B blocks Pharmaceutical Research. 15: 787-793. PMID 9619791 DOI: 10.1023/A:1011939607573 |
0.397 |
|
| 1998 |
Li Y, Kissel T. Synthesis, characteristics and in vitro degradation of star-block copolymers consisting of l-lactide, glycolide and branched multi-arm poly(ethylene oxide) Polymer. 39: 4421-4427. DOI: 10.1016/S0032-3861(97)10362-7 |
0.385 |
|
| 1998 |
Breitenbach A, Kissel T. Biodegradable comb polyesters: Part 1 synthesis, characterization and structural analysis of poly(lactide) and poly(lactide-coglycolide) grafted onto water-soluble poly(vinyl alcohol) as backbone Polymer. 39: 3261-3271. DOI: 10.1016/S0032-3861(97)10077-5 |
0.392 |
|
| 1998 |
Li Y, Volland C, Kissel T. Biodegradable brush-like graft polymers from poly(D,L-lactide) or poly(D,L-lactide-coglycolide) and charge-modified, hydrophilic dextrans as backbone—in-vitro degradation and controlled releases of hydrophilic macromolecules Polymer. 39: 3087-3097. DOI: 10.1016/S0032-3861(97)10048-9 |
0.423 |
|
| 1997 |
Schartel B, Volland C, Li YX, Wendorff JW, Kissel T. Dielectric and thermodynamic properties of biodegradable poly(D,L-lactide-co-glycolide) and the effect on the micro-encapsulation and release of captopril. Journal of Microencapsulation. 14: 475-488. PMID 9229347 DOI: 10.3109/02652049709033832 |
0.319 |
|
| 1997 |
Shard AG, Davies MC, Li YX, Volland C, Kissel T. XPS and SSIMS Analysis Revealing Surface Segregation and Short-Range Order in Solid Films of Block Copolymers of PEO and PLGA Macromolecules. 30: 3051-3057. DOI: 10.1021/Ma9519021 |
0.312 |
|
| 1997 |
Zange R, Kissel T. Comparative in vitro biocompatibility testing of polycyanoacrylates and poly(d,l-lactide-co-glycolide) using different mouse fibroblast (L929) biocompatibility test models European Journal of Pharmaceutics and Biopharmaceutics. 44: 149-157. DOI: 10.1016/S0939-6411(97)00082-9 |
0.363 |
|
| 1997 |
Morlock M, Koll H, Winter G, Kissel T. Microencapsulation of rh-erythropoietin, using biodegradable poly(d,l-lactide-co-glycolide): protein stability and the effects of stabilizing excipients European Journal of Pharmaceutics and Biopharmaceutics. 43: 29-36. DOI: 10.1016/S0939-6411(96)00017-3 |
0.353 |
|
| 1997 |
Ronneberger B, Kissel T, Anderson JM. Biocompatibility of ABA triblock copolymer microparticles consisting of poly(l-lactic-co-glycolic-acid) A-blocks attached to central poly(oxyethylene) B-blocks in rats after intramuscular injection European Journal of Pharmaceutics and Biopharmaceutics. 43: 19-28. DOI: 10.1016/S0939-6411(96)00006-9 |
0.367 |
|
| 1997 |
Li Y, Nothnagel J, Kissel T. Biodegradable brush-like graft polymers from poly(d,l-lactide) or poly(d,l-lactide-co-glycolide) and charge-modified, hydrophilic dextrans as backbone—Synthesis, characterization and in vitro degradation properties Polymer. 38: 6197-6206. DOI: 10.1016/S0032-3861(97)00178-X |
0.4 |
|
| 1996 |
Fricker G, Fahr A, Beglinger C, Kissel T, Reiter G, Drewe J. Permeation enhancement of octreotide by specific bile salts in rats and human subjects: in vitro, in vivo correlations. British Journal of Pharmacology. 117: 217-23. PMID 8825366 DOI: 10.1111/J.1476-5381.1996.Tb15177.X |
0.31 |
|
| 1996 |
Müller BG, Leuenberger H, Kissel T. Albumin nanospheres as carriers for passive drug targeting: an optimized manufacturing technique. Pharmaceutical Research. 13: 32-37. PMID 8668675 DOI: 10.1023/A:1016064930502 |
0.335 |
|
| 1996 |
Oechslein CR, Fricker G, Kissel T. Nasal delivery of octreotide: Absorption enhancement by particulate carrier systems International Journal of Pharmaceutics. 139: 25-32. DOI: 10.1016/0378-5173(96)04569-3 |
0.322 |
|
| 1996 |
Kissel T, Li YX, Volland C, Görich S, Koneberg R. Parenteral protein delivery systems using biodegradable polyesters of ABA block structure, containing hydrophobic poly(lactide-co-glycolide) A blocks and hydrophilic poly(ethylene oxide) B blocks Journal of Controlled Release. 39: 315-326. DOI: 10.1016/0168-3659(95)00163-8 |
0.401 |
|
| 1994 |
Youxin L, Volland C, Kissel T. In-vitro degradation and bovine serum albumin release of the ABA triblock copolymers consisting of poly (L(+) lactic acid), or poly(L(+) lactic acid-co-glycolic acid) A-blocks attached to central polyoxyethylene B-blocks Journal of Controlled Release. 32: 121-128. DOI: 10.1016/0168-3659(94)90050-7 |
0.377 |
|
| 1994 |
Volland C, Wolff M, Kissel T. The influence of terminal gamma-sterilization on captopril containing poly(d,l-lactide-co-glycolide) microspheres Journal of Controlled Release. 31: 293-305. DOI: 10.1016/0168-3659(94)90012-4 |
0.414 |
|
| 1993 |
Youxin L, Kissel T. Synthesis and properties of biodegradable ABA triblock copolymers consisting of poly(l-lactic acid) or poly (l-lactic-co-glycolic acid) A-blocks attached to central poly ( oxyethylene ) B-blocks Journal of Controlled Release. 27: 247-257. DOI: 10.1016/0168-3659(93)90155-X |
0.39 |
|
| 1992 |
Kissel T, Drewe J, Bantle S, Rummelt A, Beglinger C. Tolerability and absorption enhancement of intranasally administered octreotide by sodium taurodihydrofusidate in healthy subjects. Pharmaceutical Research. 9: 52-57. PMID 1589410 DOI: 10.1023/A:1018927710280 |
0.303 |
|
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