| Year |
Citation |
Score |
| 2018 |
LeGuern C, Germana S. On the Elusive TCR Specificity of Thymic Regulatory T Cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30378738 DOI: 10.1111/Ajt.15165 |
0.433 |
|
| 2016 |
Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, Abdi R, Uehara M, Kim JI, Markmann JF, Tocco G, Benichou G. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Science Immunology. 1: aaf8759. PMID 28783676 DOI: 10.1126/sciimmunol.aaf8759 |
0.38 |
|
| 2016 |
Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, Abdi R, Uehara M, Kim JI, Markmann JF, Tocco G, Benichou G. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Science Immunology. 1. PMID 27942611 DOI: 10.1126/Sciimmunol.Aaf8759 |
0.47 |
|
| 2014 |
Scalea JR, Okumi M, Villani V, Shimizu A, Nishimura H, Gillon BC, Torabi R, Cormack T, Moran S, LeGuern C, Sachs DH, Yamada K. Abrogation of renal allograft tolerance in MGH miniature swine: the role of intra-graft and peripheral factors in long-term tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2001-10. PMID 25100613 DOI: 10.1111/Ajt.12816 |
0.446 |
|
| 2013 |
Kant CD, Akiyama Y, Tanaka K, Shea S, Connolly SE, Germana S, Winn HJ, LeGuern C, Tocco G, Benichou G. Primary vascularization of allografts governs their immunogenicity and susceptibility to tolerogenesis. Journal of Immunology (Baltimore, Md. : 1950). 191: 1948-56. PMID 23833234 DOI: 10.4049/Jimmunol.1202092 |
0.371 |
|
| 2012 |
Porcheray F, Devito J, Helou Y, Dargon I, Fraser JW, Nobecourt P, Ferdman J, Germana S, Girouard TC, Kawai T, Saidman SL, Wong W, Colvin RB, Leguern C, Zorn E. Expansion of polyreactive B cells cross-reactive to HLA and self in the blood of a patient with kidney graft rejection American Journal of Transplantation. 12: 2088-2097. PMID 22510337 DOI: 10.1111/J.1600-6143.2012.04053.X |
0.412 |
|
| 2011 |
Leguern C. Regulatory T cells for tolerance therapy: revisiting the concept. Critical Reviews in Immunology. 31: 189-207. PMID 21740350 DOI: 10.1615/Critrevimmunol.V31.I3.20 |
0.361 |
|
| 2010 |
LeGuern C, Akiyama Y, Germana S, Tanaka K, Fernandez L, Iwamoto Y, Houser S, Benichou G. Intracellular MHC class II controls regulatory tolerance to allogeneic transplants. Journal of Immunology (Baltimore, Md. : 1950). 184: 2394-400. PMID 20100928 DOI: 10.4049/Jimmunol.0803664 |
0.515 |
|
| 2008 |
Martins P, Germana S, LeGuern C. 128: Influence of MHC Class II Matching on Regulatory Tolerance to Heart Transplants The Journal of Heart and Lung Transplantation. 27: S105-S106. DOI: 10.1016/J.Healun.2007.11.134 |
0.465 |
|
| 2007 |
LeGuern C. Tolerogenic property of MHC class I and class II molecules: lessons from a gene therapy approach. Frontiers in Bioscience : a Journal and Virtual Library. 12: 3133-9. PMID 17485288 DOI: 10.2741/2301 |
0.573 |
|
| 2005 |
LeGuern C. Switching on immune regulation to prevent graft rejection. Transplantation. 79: 1308-9. PMID 15912096 DOI: 10.1097/01.Tp.0000159146.85824.5B |
0.319 |
|
| 2005 |
Down JD, LeGuern C. 738. Influence of the Major Histocompatibility Complex on Immunological Rejection of Skin Grafts Expressing a Gene Therapy Reporter Gene Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.278 |
0.41 |
|
| 2004 |
Matter-Reissmann UB, Sonntag KC, Gilli UO, Leguern C, Schneider MK, Seebach JD. Human Fas-ligand expression on porcine endothelial cells does not protect against xenogeneic natural killer cytotoxicity. Xenotransplantation. 11: 43-52. PMID 14962292 DOI: 10.1111/J.1399-3089.2004.00081.X |
0.321 |
|
| 2004 |
Houser SL, McMorrow IM, Leguern C, Schwarze ML, Fuchimoto Y, Sachs DH, Madsen JC. Histomorphometric comparison of cardiac allograft vasculopathy in miniature swine Journal of Heart and Lung Transplantation. 23: 50-60. PMID 14734127 DOI: 10.1016/S1053-2498(03)00065-2 |
0.401 |
|
| 2004 |
LeGuern C. Potential role of major histocompatibility complex class II peptides in regulatory tolerance to vascularized grafts. Transplantation. 77: S35-7. PMID 14726769 DOI: 10.1097/01.Tp.0000106472.91343.8D |
0.468 |
|
| 2003 |
LeGuern C. Regulation of T-cell functions by MHC class II self-presentation. Trends in Immunology. 24: 633-8. PMID 14644136 DOI: 10.1016/J.It.2003.10.010 |
0.468 |
|
| 2003 |
Lima B, Gleit ZL, Cameron AM, Germana S, Murphy MC, Consorti R, Chang Q, Down JD, LeGuern C, Sachs DH, Huang CA. Engraftment of quiescent progenitors and conversion to full chimerism after nonmyelosuppressive conditioning and hematopoietic cell transplantation in miniature swine. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 9: 571-82. PMID 14506659 DOI: 10.1016/S1083-8791(03)00227-1 |
0.448 |
|
| 2003 |
Shimada H, Germana S, Hayashi H, Sachs DH, LeGuern C. Expression of MHC class II DQ alpha/beta heterodimers from recombinant polycistronic retroviral genomes. Surgery Today. 33: 183-9. PMID 12658383 DOI: 10.1007/S005950300041 |
0.397 |
|
| 2003 |
Andersson G, Illigens BM, Johnson KW, Calderhead D, LeGuern C, Benichou G, White-Scharf ME, Down JD. Nonmyeloablative conditioning is sufficient to allow engraftment of EGFP-expressing bone marrow and subsequent acceptance of EGFP-transgenic skin grafts in mice. Blood. 101: 4305-12. PMID 12576326 DOI: 10.1182/Blood-2002-06-1649 |
0.481 |
|
| 2002 |
Haller GW, Lima B, Kunisaki SM, Germana S, Leguern C, Huang CA, Sachs DH. MHC alloantigens elicit secondary, but not primary, indirect in vitro proliferative responses. Journal of Immunology (Baltimore, Md. : 1950). 169: 3613-21. PMID 12244152 DOI: 10.4049/Jimmunol.169.7.3613 |
0.429 |
|
| 2002 |
Denaro M, Kolber-Simonds D, Schad V, Muthukumar S, Germana S, White-Scharf ME, Banerjee PT, LeGuern C, Andersson G. Expression of xenogeneic MHC class II molecules in HLA-DR+ and -DR- cells: Influence of retrovirus vector design and cellular context Xenotransplantation. 9: 115-124. PMID 11897004 DOI: 10.1034/J.1399-3089.2002.1O038.X |
0.538 |
|
| 2002 |
McMorrow IM, Narayan K, Sachs DH, LeGuern C. New intra-renal graft genes associated with tolerance or rejection. Kidney International. 61: S85-93. PMID 11841619 DOI: 10.1046/J.1523-1755.2002.0610S1085.X |
0.473 |
|
| 2001 |
Baron C, McMorrow I, Sachs DH, LeGuern C. Persistence of dominant T cell clones in accepted solid organ transplants. Journal of Immunology (Baltimore, Md. : 1950). 167: 4154-60. PMID 11591735 DOI: 10.4049/Jimmunol.167.8.4154 |
0.489 |
|
| 2001 |
Seebach JD, Schneider MK, Comrack CA, LeGuern A, Kolb SA, Knolle PA, Germana S, DerSimonian H, LeGuern C, Sachs DH. Immortalized bone-marrow derived pig endothelial cells. Xenotransplantation. 8: 48-61. PMID 11208191 DOI: 10.1034/J.1399-3089.2001.00075.X |
0.394 |
|
| 2001 |
Baron C, Sachs DH, LeGuern C. A particular TCR beta variable region used by T cells infiltrating kidney transplants. Journal of Immunology (Baltimore, Md. : 1950). 166: 2589-96. PMID 11160320 DOI: 10.4049/Jimmunol.166.4.2589 |
0.462 |
|
| 2001 |
Sonntag KC, Emery DW, Yasumoto A, Haller G, Germana S, Sablinski T, Shimizu A, Yamada K, Shimada H, Arn S, Sachs DH, LeGuern C. Tolerance to solid organ transplants through transfer of MHC class II genes Journal of Clinical Investigation. 107: 65-71. PMID 11134181 DOI: 10.1172/Jci11015 |
0.561 |
|
| 2001 |
Sonntag KC, Nebhard N, Haller GW, Yasumoto A, Sachs DH, LeGuern C. Assessment of transduction rates of porcine bone marrow. Journal of Hematotherapy & Stem Cell Research. 9: 721-6. PMID 11091496 DOI: 10.1089/15258160050196768 |
0.359 |
|
| 2000 |
Sonntag KC, Haller GW, Giauffret D, Germana S, Reeves SA, Levy J, Sachs DH, LeGuern C. Regulated expression of an MHC class II gene from a promoter-inducible retrovirus Human Gene Therapy. 11: 1961-1969. PMID 11020796 DOI: 10.1089/10430340050143390 |
0.559 |
|
| 2000 |
Salmon H, Johnson I, Germana S, Haller GW, Sachs DH, Leguern C. Dendritic cells enriched from swine thymus co-express CD1, CD2 and major histocompatibility complex class II and actively stimulate alloreactive T lymphocytes. Scandinavian Journal of Immunology. 52: 164-72. PMID 10931384 DOI: 10.1046/J.1365-3083.2000.00768.X |
0.332 |
|
| 2000 |
Gojo S, Cooper DK, Iacomini J, LeGuern C. Gene therapy and transplantation. Transplantation. 69: 1995-9. PMID 10852583 DOI: 10.1097/00007890-200005270-00001 |
0.408 |
|
| 2000 |
Gojo S, Shimizu A, Ierino FL, Banerjee PT, Cooper DK, LeGuern C, Sachs DH. Xenogeneic and allogeneic skin grafting after retrovirus-mediated SLA class II DR gene transfer in baboons. Transplantation Proceedings. 32: 289-90. PMID 10715420 DOI: 10.1016/S0041-1345(99)00960-4 |
0.478 |
|
| 1999 |
Shimada H, Germana S, Sonntag KC, Banerjee P, Moore D, Sachs DH, LeGuern C. MHC class II alpha/beta heterodimeric cell surface molecules expressed from a single proviral genome. Human Gene Therapy. 10: 2397-405. PMID 10515459 DOI: 10.1089/10430349950017040 |
0.68 |
|
| 1999 |
Shimada H, Alexander RC, Germana S, Sachs DH, Leguern C. Recombinant retrovirus vectors for the expression of MHC class II heterodimers Surgery Today. 29: 533-541. PMID 10385368 DOI: 10.1007/Bf02482348 |
0.531 |
|
| 1999 |
Seebach JD, Pazmany L, Waneck GL, Minja F, Germana S, LeGuern C, Sachs DH. HLA-G expression on porcine endothelial cells protects partially against direct human NK cytotoxicity but not against ADCC. Transplantation Proceedings. 31: 1864-5. PMID 10371975 DOI: 10.1016/S0041-1345(99)00190-6 |
0.354 |
|
| 1999 |
Ierino FL, Gojo S, Banerjee PT, Giovino M, Xu Y, Gere J, Kaynor C, Awwad M, Monroy R, Rembert J, Hatch T, Foley A, Kozlowski T, Yamada K, Neethling FA, ... ... LeGuern C, et al. Transfer of swine major histocompatibility complex class II genes into autologous bone marrow cells of baboons for the induction of tolerance across xenogeneic barriers. Transplantation. 67: 1119-28. PMID 10232561 DOI: 10.1097/00007890-199904270-00006 |
0.506 |
|
| 1999 |
Haller GW, Kunisaki SM, Germana S, LeGuern C, Sachs DH. MLR RESPONSES TO ALLOGENEIC MHC CLASS II PEPTIDES REQUIRES PRIMING OF THE RESPONDER Transplantation. 67: S42. DOI: 10.1097/00007890-199904150-00169 |
0.385 |
|
| 1998 |
Emery DW, Shimada H, Germana S, Sachs DH, LeGuern C. Transfer of porcine MHC DRα into IEα-deficient murine bone marrow results in reduced IE-restricted Vβ usage Transplantation. 66: 1081-1088. PMID 9808495 DOI: 10.1097/00007890-199810270-00019 |
0.546 |
|
| 1997 |
Emery DW, Sablinski T, Shimada H, Germana S, Gianello P, Foley A, Shulman S, Arn S, Fishman J, Lorf T, Nickeleit V, Colvin RB, Sachs DH, LeGuern C. Expression of an allogeneic MHC DRB transgene, through retroviral transduction of bone marrow, induces specific reduction of alloreactivity Transplantation. 64: 1414-1423. PMID 9392304 DOI: 10.1097/00007890-199711270-00007 |
0.566 |
|
| 1997 |
Mayfield RS, Hayashi H, Sawada T, Bergen K, LeGuern C, Sykes M, Sachs DH, Iacomini J. The mechanism of specific prolongation of class I-mismatched skin grafts induced by retroviral gene therapy. European Journal of Immunology. 27: 1177-81. PMID 9174608 DOI: 10.1002/Eji.1830270519 |
0.477 |
|
| 1997 |
Giangrande I, Yamada K, Germana S, Sachs D, LeGuern C. Tolerant cells infiltrating class I mismatched swine kidney allografts lack the CD4 single positive subset and down regulate TCR gene expression. Transplantation Proceedings. 29: 1164. PMID 9123254 DOI: 10.1016/S0041-1345(96)00513-1 |
0.437 |
|
| 1997 |
Hayashi H, Mayfield RS, Sawada T, Germana S, Sykes M, Iacomini J, Sachs DH, LeGuern C. Role of the thymus in donor specific hyporesponsiveness induced by retroviral transduction of bone marrow using an MHC class I gene. Transplantation Proceedings. 29: 1133. PMID 9123234 DOI: 10.1016/S0041-1345(96)00467-8 |
0.48 |
|
| 1997 |
Yasumoto A, Yamada K, Sablinski T, LeGuern C, Sykes M, Sachs DH. Mechanism of tolerance following class II gene transduction of autologous swine bone marrow. Transplantation Proceedings. 29: 1132. PMID 9123233 DOI: 10.1016/S0041-1345(96)00466-6 |
0.461 |
|
| 1997 |
Germana S, Shimada H, Sachs DH, LeGuern C. Retroviral vectors transfer functional MHC class II heterodimers into bone marrow: a genetic approach to tolerance induction. Transplantation Proceedings. 29: 1129. PMID 9123230 DOI: 10.1016/S0041-1345(96)00463-0 |
0.433 |
|
| 1997 |
Giangrande I, Yamada K, Arn S, Lorf T, Sachs DH, LeGuern C. Selective increase in CD4-positive graft-infiltrating mononuclear cells among the infiltrates in class I disparate kidney grafts undergoing rejection. Transplantation. 63: 722-8. PMID 9075845 DOI: 10.1097/00007890-199703150-00019 |
0.376 |
|
| 1997 |
Blancho G, Gianello PR, Lorf T, Germana S, Giangrande I, Mourad G, Colvin RB, Sachs DH, LeGuern C. Molecular and cellular events implicated in local tolerance to kidney allografts in miniature swine. Transplantation. 63: 26-33. PMID 9000656 DOI: 10.1097/00007890-199701150-00006 |
0.433 |
|
| 1997 |
Banerjee PT, Ierino FL, Kaynor GC, Giovino M, Hawley R, Rosa MD, LeGuern C, Sachs DH, Monroy R. Expression of swine MHC class II genes in a cynomolgus monkey: Retro virus-mediated gene therapy in a preclinical transplantation model Xenotransplantation. 4: 174-185. DOI: 10.1111/J.1399-3089.1997.Tb00181.X |
0.581 |
|
| 1997 |
Banerjee PT, Kaynor GC, Muthukumar S, Denaro M, Shimada H, Zhu S, Rosa MD, Sachs DH, LeGuern C. A polycistronic retrovirus vector for expression of swine MHC class II DRaα/β heterodimers Xenotransplantation. 4: 161-173. DOI: 10.1111/J.1399-3089.1997.Tb00180.X |
0.472 |
|
| 1996 |
Hayashi H, LeGuern C, Sachs DH, Sykes M. Long-term engraftment of precultured post-5-fluorouracil allogeneic marrow in mice conditioned with a nonmyeloablative regimen: relevance for a gene therapy approach to tolerance induction. Transplant Immunology. 4: 86-90. PMID 8762020 DOI: 10.1016/S0966-3274(96)80044-X |
0.464 |
|
| 1995 |
Blancho G, Gianello P, Germana S, Baetscher M, Sachs DH, LeGuern C. Molecular identification of porcine interleukin 10: regulation of expression in a kidney allograft model. Proceedings of the National Academy of Sciences of the United States of America. 92: 2800-4. PMID 7708727 DOI: 10.1073/Pnas.92.7.2800 |
0.315 |
|
| 1995 |
LeGuern C, Shimada H, Emery DW, Germana S, Shafer GE, Sachs DH. Retrovirus-mediated transfer of MHC class II cDNA into swine bone marrow cells Journal of Molecular Medicine. 73: 269-278. PMID 7583449 DOI: 10.1007/Bf00231613 |
0.468 |
|
| 1993 |
Emery D, Shafer G, Karson E, Sachs D, LeGuern C. Retrovirus-mediated transfer and expression of an allogeneic major histocompatibility complex class II DRB cDNA in swine bone marrow cultures Blood. 81: 2460-2465. DOI: 10.1182/Blood.V81.9.2460.Bloodjournal8192460 |
0.462 |
|
| 1992 |
Marche PN, Laverrière A, LeGuern C, Kindt TJ. A gene remnant in the rabbit MHC related to HLA-DR alpha. Research in Immunology. 142: 525-32. PMID 1812548 DOI: 10.1016/0923-2494(91)90097-3 |
0.42 |
|
| 1991 |
Gustafsson K, Germana S, Hirsch F, Pratt K, LeGuern C, Sachs DH. Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related mammalian species. Proceedings of the National Academy of Sciences of the United States of America. 87: 9798-802. PMID 2124703 DOI: 10.1073/Pnas.87.24.9798 |
0.396 |
|
| 1991 |
Shafer GE, Emery DW, Gustafsson K, Germana S, French Anderson W, Sachs DH, Leguern C. Expression of a swine class II gene in murine bone marrow hematopoietic cells by retroviral-mediated gene transfer Proceedings of the National Academy of Sciences of the United States of America. 88: 9760-9764. PMID 1946400 DOI: 10.1073/Pnas.88.21.9760 |
0.474 |
|
| 1990 |
Hirsch F, Sachs DH, Gustafsson K, Pratt K, Germana S, LeGuern C. Class II genes of miniature swine. III. Characterization of an expressed pig class II gene homologous to HLA-DQA. Immunogenetics. 31: 52-6. PMID 2298465 DOI: 10.1007/Bf00702489 |
0.465 |
|
| 1990 |
Pratt K, Sachs DH, Germana S, el-Gamil M, Hirsch F, Gustafsson K, LeGuern C. Class II genes of miniature swine. II. Molecular identification and characterization of B (beta) genes from the SLAc haplotype. Immunogenetics. 31: 1-6. PMID 2298461 DOI: 10.1007/Bf00702482 |
0.404 |
|
| 1989 |
Laverriere A, Kulaga H, Kindt TJ, LeGuern C, Marche PN. A rabbit class II MHC gene with strong similarities to HLA-DRA. Immunogenetics. 30: 137-40. PMID 2759665 DOI: 10.1007/Bf02421545 |
0.42 |
|
| 1989 |
Marche PN, Rebiere MC, Laverrière A, English DW, LeGuern C, Kindt TJ. Definition of rabbit class I and class II MHC gene haplotypes using molecular typing procedures. Immunogenetics. 29: 273-6. PMID 2564845 DOI: 10.1007/BF00717913 |
0.345 |
|
| 1989 |
Jouvin-Marche E, Morgado MG, Leguern C, Voegtle D, Bonhomme F, Cazenave PA. The mouse Igh-1a and Igh-1b H chain constant regions are derived from two distinct isotypic genes. Immunogenetics. 29: 92-7. PMID 2563358 DOI: 10.1007/Bf00395856 |
0.324 |
|
| 1987 |
LeGuern C, Weissman JD, Marche PN, Jouvin-Marche E, Laverrière A, Bagnato MR, Kindt TJ. Sequence determination of a transcribed rabbit class II gene with homology to HLA-DQ alpha. Immunogenetics. 25: 104-9. PMID 3493213 DOI: 10.1007/Bf00364275 |
0.431 |
|
| 1985 |
LeGuern C, Marche PN, Kindt TJ. Molecular evidence for five distinct MHC class II alpha genes in the rabbit. Immunogenetics. 22: 141-8. PMID 3861576 DOI: 10.1007/Bf00563511 |
0.456 |
|
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