Robyn S. Klein, M.D. Ph.D. - Publications

Affiliations: 
Infectious Diseases Washington University School of Medicine, St. Louis, MO, United States 
Area:
Neuroimmunology

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ai S, Arutyunov A, Liu J, Hill JD, Jiang X, Klein RS. CCR2 limits inflammatory functions of CD8 TRM cells that impair recognition memory during recovery from WNV encephalitis. Biorxiv : the Preprint Server For Biology. PMID 39345540 DOI: 10.1101/2024.09.17.613307  0.517
2024 Vanderheiden A, Hill JD, Jiang X, Deppen B, Bamunuarachchi G, Soudani N, Joshi A, Cain MD, Boon ACM, Klein RS. Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice. Nature Immunology. 25: 1158-1171. PMID 38902519 DOI: 10.1038/s41590-024-01868-z  0.508
2023 Vanderheiden A, Hill J, Jiang X, Deppen B, Bamunuarachchi G, Soudani N, Joshi A, Cain MD, Boon ACM, Klein RS. Vaccination prevents IL-1β-mediated cognitive deficits after COVID-19. Research Square. PMID 37790551 DOI: 10.21203/rs.3.rs-3353171/v1  0.507
2023 Agner SC, Brier LM, Hill J, Liu E, Bice A, Rahn RM, Culver JP, Klein RS. Myeloid cell activation during Zika virus encephalitis predicts recovery of functional cortical connectivity. Biorxiv : the Preprint Server For Biology. PMID 37461558 DOI: 10.1101/2023.07.06.547991  0.534
2020 Ngwaga T, Kong L, Lin D, Schoborg C, Taylor LE, Mayer KH, Klein RS, Celentano DD, Sobel JD, Jamieson DJ, King CC, Tavis JE, Blackard JT. Diversity of the hepatitis C virus NS5B gene during HIV co-infection. Plos One. 15: e0237162. PMID 32750098 DOI: 10.1371/Journal.Pone.0237162  0.304
2020 Ai S, Klein RS. Update on T cells in the virally infected brain: friends and foes. Current Opinion in Neurology. PMID 32304440 DOI: 10.1097/Wco.0000000000000825  0.327
2020 Salimi H, Cain MD, Jiang X, Roth RA, Beatty WL, Sun C, Klimstra WB, Hou J, Klein RS. Encephalitic Alphaviruses Exploit Caveola-Mediated Transcytosis at the Blood-Brain Barrier for Central Nervous System Entry. Mbio. 11. PMID 32047126 DOI: 10.1128/Mbio.02731-19  0.387
2020 Williams JL, Manivasagam S, Smith BC, Sim J, Vollmer LL, Daniels BP, Russell JH, Klein RS. Astrocyte-T cell crosstalk regulates region-specific neuroinflammation. Glia. PMID 31961459 DOI: 10.1002/Glia.23783  0.326
2019 Cain MD, Salimi H, Diamond MS, Klein RS. Mechanisms of Pathogen Invasion into the Central Nervous System. Neuron. 103: 771-783. PMID 31487528 DOI: 10.1016/J.Neuron.2019.07.015  0.322
2019 Janowski AB, Klein RS, Wang D. Differential Infection of Neural Cells by Astroviruses. Mbio. 10. PMID 31289185 DOI: 10.1128/Mbio.01455-19  0.375
2019 Garber C, Soung A, Vollmer LL, Kanmogne M, Last A, Brown J, Klein RS. T cells promote microglia-mediated synaptic elimination and cognitive dysfunction during recovery from neuropathogenic flaviviruses. Nature Neuroscience. PMID 31235930 DOI: 10.1038/S41593-019-0427-Y  0.352
2019 Klein RS, Garber C, Funk KE, Salimi H, Soung A, Kanmogne M, Manivasagam S, Agner S, Cain M. Neuroinflammation During RNA Viral Infections. Annual Review of Immunology. 37: 73-95. PMID 31026414 DOI: 10.1146/Annurev-Immunol-042718-041417  0.359
2019 Santiago-Tirado FH, Klein RS, Doering TL. An In Vitro Brain Endothelial Model for Studies of Cryptococcal Transmigration into the Central Nervous System. Current Protocols in Microbiology. e78. PMID 30776307 DOI: 10.1002/Cpmc.78  0.325
2019 Funk KE, Klein RS. CSF1R antagonism limits local restimulation of antiviral CD8 T cells during viral encephalitis. Journal of Neuroinflammation. 16: 22. PMID 30704498 DOI: 10.1186/S12974-019-1397-4  0.35
2018 Soung A, Klein RS. Viral Encephalitis and Neurologic Diseases: Focus on Astrocytes. Trends in Molecular Medicine. PMID 30314877 DOI: 10.1016/J.Molmed.2018.09.001  0.364
2018 Luo H, Winkelmann ER, Zhu S, Ru W, Mays E, Silvas JA, Vollmer LL, Gao J, Peng BH, Bopp NE, Cromer C, Shan C, Xie G, Li G, Tesh R, ... ... Klein RS, et al. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. The Journal of Clinical Investigation. PMID 30247157 DOI: 10.1172/Jci99902  0.38
2018 Agner SC, Klein RS. Viruses have multiple paths to central nervous system pathology. Current Opinion in Neurology. PMID 29561519 DOI: 10.1097/Wco.0000000000000556  0.345
2017 Klein RS. Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly. Cell Host & Microbe. 22: 9-11. PMID 28704657 DOI: 10.1016/J.Chom.2017.06.015  0.321
2017 Klein RS, Hunter CA. Protective and Pathological Immunity during Central Nervous System Infections. Immunity. 46: 891-909. PMID 28636958 DOI: 10.1016/J.Immuni.2017.06.012  0.325
2017 Cain MD, Salimi H, Gong Y, Yang L, Hamilton SL, Heffernan JR, Hou J, Miller MJ, Klein RS. Virus entry and replication in the brain precedes blood-brain barrier disruption during intranasal alphavirus infection. Journal of Neuroimmunology. PMID 28501330 DOI: 10.1016/J.Jneuroim.2017.04.008  0.369
2017 Klein RS, Voskuhl R, Segal BM, Dittel BN, Lane TE, Bethea JR, Carson MJ, Colton C, Rosi S, Anderson A, Piccio L, Goverman JM, Benveniste EN, Brown MA, Tiwari-Woodruff SK, et al. Speaking out about gender imbalance in invited speakers improves diversity. Nature Immunology. 18: 475-478. PMID 28418385 DOI: 10.1038/Ni.3707  0.463
2017 Daniels BP, Jujjavarapu H, Durrant DM, Williams JL, Green RR, White JP, Lazear HM, Gale M, Diamond MS, Klein RS. Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection. The Journal of Clinical Investigation. PMID 28134626 DOI: 10.1172/Jci88720  0.372
2017 Klein RS, Garber C, Howard N. Infectious immunity in the central nervous system and brain function. Nature Immunology. PMID 28092376 DOI: 10.1038/Ni.3656  0.345
2016 Vasek MJ, Garber C, Dorsey D, Durrant DM, Bollman B, Soung A, Yu J, Perez-Torres C, Frouin A, Wilton DK, Funk K, DeMasters BK, Jiang X, Bowen JR, Mennerick S, ... ... Klein RS, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 534: 538-543. PMID 27337340 DOI: 10.1038/Nature18283  0.335
2016 Salimi H, Cain MD, Klein RS. Encephalitic Arboviruses: Emergence, Clinical Presentation, and Neuropathogenesis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27220616 DOI: 10.1007/S13311-016-0443-5  0.344
2016 Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, Mysorekar IU, Diamond MS. Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell. PMID 27180225 DOI: 10.1016/J.Cell.2016.05.008  0.322
2016 Hou J, Baker LA, Zhou L, Klein RS. Viral interactions with the blood-brain barrier: old dog, new tricks. Tissue Barriers. 4: e1142492. PMID 27141421 DOI: 10.1080/21688370.2016.1142492  0.34
2015 Durrant DM, Daniels BP, Pasieka T, Dorsey D, Klein RS. CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system. Journal of Neuroinflammation. 12: 233. PMID 26667390 DOI: 10.1186/S12974-015-0447-9  0.382
2015 Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, Gorman MJ, Lemke G, Klein RS, Diamond MS. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. Nature Medicine. PMID 26523970 DOI: 10.1038/Nm.3974  0.352
2015 Daniels BP, Klein RS. Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System. Plos Pathogens. 11: e1005096. PMID 26379171 DOI: 10.1371/Journal.Ppat.1005096  0.355
2015 Lazear HM, Daniels BP, Pinto AK, Huang AC, Vick SC, Doyle SE, Gale M, Klein RS, Diamond MS. Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier. Science Translational Medicine. 7: 284ra59. PMID 25904743 DOI: 10.1126/Scitranslmed.Aaa4304  0.355
2015 Daniels BP, Klein RS. Viral sensing at the blood-brain barrier: new roles for innate immunity at the CNS vasculature. Clinical Pharmacology and Therapeutics. 97: 372-9. PMID 25670037 DOI: 10.1002/Cpt.75  0.357
2015 Cantoni C, Bollman B, Licastro D, Xie M, Mikesell R, Schmidt R, Yuede CM, Galimberti D, Olivecrona G, Klein RS, Cross AH, Otero K, Piccio L. TREM2 regulates microglial cell activation in response to demyelination in vivo. Acta Neuropathologica. 129: 429-47. PMID 25631124 DOI: 10.1007/S00401-015-1388-1  0.533
2014 Durrant DM, Daniels BP, Klein RS. IL-1R1 signaling regulates CXCL12-mediated T cell localization and fate within the central nervous system during West Nile Virus encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 193: 4095-106. PMID 25200953 DOI: 10.4049/Jimmunol.1401192  0.357
2014 Daniels BP, Holman DW, Cruz-Orengo L, Jujjavarapu H, Durrant DM, Klein RS. Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals. Mbio. 5: e01476-14. PMID 25161189 DOI: 10.1128/Mbio.01476-14  0.339
2014 Williams JL, Holman DW, Klein RS. Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers. Frontiers in Cellular Neuroscience. 8: 154. PMID 24920943 DOI: 10.3389/Fncel.2014.00154  0.323
2014 Cruz-Orengo L, Daniels BP, Dorsey D, Basak SA, Grajales-Reyes JG, McCandless EE, Piccio L, Schmidt RE, Cross AH, Crosby SD, Klein RS. Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. The Journal of Clinical Investigation. 124: 2571-84. PMID 24812668 DOI: 10.1172/Jci73408  0.731
2014 Sun T, Vasek MJ, Klein RS. Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone. Plos One. 9: e96442. PMID 24802239 DOI: 10.1371/Journal.Pone.0096442  0.344
2014 Reddy AS, Patel JR, Vogler C, Klein RS, Sands MS. Central nervous system pathology progresses independently of KC and CXCR2 in globoid-cell leukodystrophy. Plos One. 8: e64647. PMID 23755134 DOI: 10.1371/Journal.Pone.0064647  0.315
2013 Cross AH, Klein RS. Comment: assessing humoral immunocompetence after alemtuzumab treatment in MS. Neurology. 81: 875. PMID 23925764 DOI: 10.1212/Wnl.0B013E3182A352C6  0.504
2013 Durrant DM, Robinette ML, Klein RS. IL-1R1 is required for dendritic cell-mediated T cell reactivation within the CNS during West Nile virus encephalitis. The Journal of Experimental Medicine. 210: 503-16. PMID 23460727 DOI: 10.1084/Jem.20121897  0.341
2013 Daniels BP, Cruz-Orengo L, Pasieka TJ, Couraud PO, Romero IA, Weksler B, Cooper JA, Doering TL, Klein RS. Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier. Journal of Neuroscience Methods. 212: 173-9. PMID 23068604 DOI: 10.1016/J.Jneumeth.2012.10.001  0.309
2012 Cross AH, Klein RS, Piccio L. Rituximab combination therapy in relapsing multiple sclerosis. Therapeutic Advances in Neurological Disorders. 5: 311-9. PMID 23139702 DOI: 10.1177/1756285612461165  0.519
2012 Patel JR, Williams JL, Muccigrosso MM, Liu L, Sun T, Rubin JB, Klein RS. Astrocyte TNFR2 is required for CXCL12-mediated regulation of oligodendrocyte progenitor proliferation and differentiation within the adult CNS. Acta Neuropathologica. 124: 847-60. PMID 22933014 DOI: 10.1007/S00401-012-1034-0  0.311
2012 Szretter KJ, Daniels BP, Cho H, Gainey MD, Yokoyama WM, Gale M, Virgin HW, Klein RS, Sen GC, Diamond MS. 2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. Plos Pathogens. 8: e1002698. PMID 22589727 DOI: 10.1371/Journal.Ppat.1002698  0.367
2011 Wang Y, Wang Q, Haldar JP, Yeh FC, Xie M, Sun P, Tu TW, Trinkaus K, Klein RS, Cross AH, Song SK. Quantification of increased cellularity during inflammatory demyelination. Brain : a Journal of Neurology. 134: 3590-601. PMID 22171354 DOI: 10.1093/Brain/Awr307  0.47
2011 Schoenfisch AL, Dollard SC, Amin M, Gardner LI, Klein RS, Mayer K, Rompalo A, Sobel JD, Cannon MJ. Cytomegalovirus (CMV) shedding is highly correlated with markers of immunosuppression in CMV-seropositive women. Journal of Medical Microbiology. 60: 768-74. PMID 21393456 DOI: 10.1099/Jmm.0.027771-0  0.334
2011 Cruz-Orengo L, Holman DW, Dorsey D, Zhou L, Zhang P, Wright M, McCandless EE, Patel JR, Luker GD, Littman DR, Russell JH, Klein RS. CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity. The Journal of Experimental Medicine. 208: 327-39. PMID 21300915 DOI: 10.1084/Jem.20102010  0.332
2011 Holman DW, Klein RS, Ransohoff RM. The blood-brain barrier, chemokines and multiple sclerosis. Biochimica Et Biophysica Acta. 1812: 220-30. PMID 20692338 DOI: 10.1016/J.Bbadis.2010.07.019  0.319
2010 Szretter KJ, Daffis S, Patel J, Suthar MS, Klein RS, Gale M, Diamond MS. The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system. Journal of Virology. 84: 12125-38. PMID 20881045 DOI: 10.1128/Jvi.01026-10  0.362
2010 Piccio L, Naismith RT, Trinkaus K, Klein RS, Parks BJ, Lyons JA, Cross AH. Changes in B- and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis. Archives of Neurology. 67: 707-14. PMID 20558389 DOI: 10.1001/Archneurol.2010.99  0.489
2010 Patel JR, McCandless EE, Dorsey D, Klein RS. CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proceedings of the National Academy of Sciences of the United States of America. 107: 11062-7. PMID 20534485 DOI: 10.1073/Pnas.1006301107  0.326
2010 Theiler RN, Farr SL, Karon JM, Paramsothy P, Viscidi R, Duerr A, Cu-Uvin S, Sobel J, Shah K, Klein RS, Jamieson DJ. High-risk human papillomavirus reactivation in human immunodeficiency virus-infected women: risk factors for cervical viral shedding. Obstetrics and Gynecology. 115: 1150-8. PMID 20502284 DOI: 10.1097/Aog.0B013E3181E00927  0.322
2009 Floris-Moore M, Fayad ZA, Berman JW, Mani V, Schoenbaum EE, Klein RS, Weinshelbaum KB, Fuster V, Howard AA, Lo Y, Schecter AD. Association of HIV viral load with monocyte chemoattractant protein-1 and atherosclerosis burden measured by magnetic resonance imaging. Aids (London, England). 23: 941-9. PMID 19318907 DOI: 10.1097/Qad.0B013E328329C76B  0.349
2008 McCandless EE, Zhang B, Diamond MS, Klein RS. CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proceedings of the National Academy of Sciences of the United States of America. 105: 11270-5. PMID 18678898 DOI: 10.1073/Pnas.0800898105  0.37
2008 Shrestha B, Zhang B, Purtha WE, Klein RS, Diamond MS. Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system. Journal of Virology. 82: 8956-64. PMID 18632856 DOI: 10.1128/Jvi.01118-08  0.303
2008 Wiener M, Lo Y, Klein RS. Abnormal thyroid function in older men with or at risk for HIV infection. Hiv Medicine. 9: 544-9. PMID 18554308 DOI: 10.1111/J.1468-1293.2008.00601.X  0.316
2008 Klein RS, Diamond MS. Immunological headgear: antiviral immune responses protect against neuroinvasive West Nile virus. Trends in Molecular Medicine. 14: 286-94. PMID 18539532 DOI: 10.1016/J.Molmed.2008.05.004  0.309
2008 McCandless EE, Piccio L, Woerner BM, Schmidt RE, Rubin JB, Cross AH, Klein RS. Pathological expression of CXCL12 at the blood-brain barrier correlates with severity of multiple sclerosis. The American Journal of Pathology. 172: 799-808. PMID 18276777 DOI: 10.2353/Ajpath.2008.070918  0.521
2008 Zhang B, Chan YK, Lu B, Diamond MS, Klein RS. CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. Journal of Immunology (Baltimore, Md. : 1950). 180: 2641-9. PMID 18250476 DOI: 10.4049/Jimmunol.180.4.2641  0.384
2008 Klein RS. A moving target: the multiple roles of CCR5 in infectious diseases. The Journal of Infectious Diseases. 197: 183-6. PMID 18179384 DOI: 10.1086/524692  0.324
2007 McCandless EE, Klein RS. Molecular targets for disrupting leukocyte trafficking during multiple sclerosis. Expert Reviews in Molecular Medicine. 9: 1-19. PMID 17637110 DOI: 10.1017/S1462399407000397  0.339
2007 Sitati E, McCandless EE, Klein RS, Diamond MS. CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile virus encephalitis. Journal of Virology. 81: 9801-11. PMID 17626103 DOI: 10.1128/Jvi.00941-07  0.305
2006 McCandless EE, Wang Q, Woerner BM, Harper JM, Klein RS. CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 177: 8053-64. PMID 17114479 DOI: 10.4049/Jimmunol.177.11.8053  0.336
2006 Diamond MS, Klein RS. A genetic basis for human susceptibility to West Nile virus. Trends in Microbiology. 14: 287-9. PMID 16750369 DOI: 10.1016/J.Tim.2006.05.004  0.354
2006 Gimenez MA, Sim J, Archambault AS, Klein RS, Russell JH. A tumor necrosis factor receptor 1-dependent conversation between central nervous system-specific T cells and the central nervous system is required for inflammatory infiltration of the spinal cord. The American Journal of Pathology. 168: 1200-9. PMID 16565495 DOI: 10.2353/Ajpath.2006.050332  0.316
2006 Duerr A, Paramsothy P, Jamieson DJ, Heilig CM, Klein RS, Cu-Uvin S, Schuman P, Anderson JR. Effect of HIV infection on atypical squamous cells of undetermined significance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 42: 855-61. PMID 16477565 DOI: 10.1086/500404  0.31
2006 Kim JH, Budde MD, Liang HF, Klein RS, Russell JH, Cross AH, Song SK. Detecting axon damage in spinal cord from a mouse model of multiple sclerosis. Neurobiology of Disease. 21: 626-32. PMID 16298135 DOI: 10.1016/J.Nbd.2005.09.009  0.475
2005 Klein RS, Lin E, Zhang B, Luster AD, Tollett J, Samuel MA, Engle M, Diamond MS. Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis. Journal of Virology. 79: 11457-66. PMID 16103196 DOI: 10.1128/Jvi.79.17.11457-11466.2005  0.566
2005 Klein RS, Rubin JB, Luster AD. Chemokines and Central Nervous System Physiology Current Topics in Membranes. 55: 159-187. DOI: 10.1016/S1063-5823(04)55007-X  0.319
2004 Diamond MS, Klein RS. West Nile virus: crossing the blood-brain barrier. Nature Medicine. 10: 1294-5. PMID 15580248 DOI: 10.1038/Nm1204-1294  0.303
2004 Klein RS, Rubin JB. Immune and nervous system CXCL12 and CXCR4: parallel roles in patterning and plasticity. Trends in Immunology. 25: 306-14. PMID 15145320 DOI: 10.1016/J.It.2004.04.002  0.323
2004 Klein RS. Regulation of neuroinflammation: the role of CXCL10 in lymphocyte infiltration during autoimmune encephalomyelitis. Journal of Cellular Biochemistry. 92: 213-22. PMID 15108349 DOI: 10.1002/Jcb.20052  0.336
2004 Klein RS, Izikson L, Means T, Gibson HD, Lin E, Sobel RA, Weiner HL, Luster AD. IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 172: 550-9. PMID 14688366 DOI: 10.4049/Jimmunol.172.1.550  0.556
2003 Smith DK, Gardner LI, Phelps R, Hamburger ME, Carpenter C, Klein RS, Rompalo A, Schuman P, Holmberg SD. Mortality rates and causes of death in a cohort of HIV-infected and uninfected women, 1993-1999. Journal of Urban Health : Bulletin of the New York Academy of Medicine. 80: 676-88. PMID 14709715 DOI: 10.1093/Jurban/Jtg074  0.301
2003 Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, Schmidt K, Kieran MW, Luster AD, Segal RA. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proceedings of the National Academy of Sciences of the United States of America. 100: 13513-8. PMID 14595012 DOI: 10.1073/Pnas.2235846100  0.508
2003 Jones CY, Hogan JW, Snyder B, Klein RS, Rompalo A, Schuman P, Carpenter CC. Overweight and human immunodeficiency virus (HIV) progression in women: associations HIV disease progression and changes in body mass index in women in the HIV epidemiology research study cohort. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: S69-80. PMID 12942377 DOI: 10.1086/375889  0.32
2003 Schuman P, Ohmit SE, Klein RS, Duerr A, Cu-Uvin S, Jamieson DJ, Anderson J, Shah KV. Longitudinal study of cervical squamous intraepithelial lesions in human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative women. The Journal of Infectious Diseases. 188: 128-36. PMID 12825181 DOI: 10.1086/375783  0.309
2003 Ohmit SE, Sobel JD, Schuman P, Duerr A, Mayer K, Rompalo A, Klein RS. Longitudinal study of mucosal Candida species colonization and candidiasis among human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative women. The Journal of Infectious Diseases. 188: 118-27. PMID 12825180 DOI: 10.1086/375746  0.31
2003 Stover CT, Smith DK, Schmid DS, Pellett PE, Stewart JA, Klein RS, Mayer K, Vlahov D, Schuman P, Cannon MJ. Prevalence of and risk factors for viral infections among human immunodeficiency virus (HIV)-infected and high-risk HIV-uninfected women. The Journal of Infectious Diseases. 187: 1388-96. PMID 12717619 DOI: 10.1086/374649  0.352
2003 Duerr A, Heilig CM, Meikle SF, Cu-Uvin S, Klein RS, Rompalo A, Sobel JD. Incident and persistent vulvovaginal candidiasis among human immunodeficiency virus-infected women: Risk factors and severity. Obstetrics and Gynecology. 101: 548-56. PMID 12636961 DOI: 10.1016/S0029-7844(02)02729-1  0.344
2002 Shah SS, McGowan JP, Smith C, Blum S, Klein RS. Comorbid conditions, treatment, and health maintenance in older persons with human immunodeficiency virus infection in New York City. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 35: 1238-43. PMID 12410484 DOI: 10.1086/343048  0.305
2002 Park JC, Buono D, Smith DK, Peipert JF, Sobel J, Rompalo A, Klein RS. Urinary tract infections in women with or at risk for human immunodeficiency virus infection. American Journal of Obstetrics and Gynecology. 187: 581-8. PMID 12237631 DOI: 10.1067/Mob.2002.125894  0.323
2002 Izikson L, Klein RS, Luster AD, Weiner HL. Targeting monocyte recruitment in CNS autoimmune disease. Clinical Immunology (Orlando, Fla.). 103: 125-31. PMID 12027417 DOI: 10.1006/Clim.2001.5167  0.538
2002 Borghesani PR, Peyrin JM, Klein R, Rubin J, Carter AR, Schwartz PM, Luster A, Corfas G, Segal RA. BDNF stimulates migration of cerebellar granule cells. Development (Cambridge, England). 129: 1435-42. PMID 11880352  0.447
2001 Phelps RM, Smith DK, Heilig CM, Gardner LI, Carpenter CC, Klein RS, Jamieson DJ, Vlahov D, Schuman P, Holmberg SD. Cancer incidence in women with or at risk for HIV. International Journal of Cancer. Journal International Du Cancer. 94: 753-7. PMID 11745473 DOI: 10.1002/Ijc.1528  0.308
2001 Jamieson DJ, Duerr A, Klein RS, Paramsothy P, Brown W, Cu-Uvin S, Rompalo A, Sobel J. Longitudinal analysis of bacterial vaginosis: findings from the HIV epidemiology research study. Obstetrics and Gynecology. 98: 656-63. PMID 11576584 DOI: 10.1016/S0029-7844(01)01525-3  0.308
2001 Duerr A, Kieke B, Warren D, Shah K, Burk R, Peipert JF, Schuman P, Klein RS. Human papillomavirus-associated cervical cytologic abnormalities among women with or at risk of infection with human immunodeficiency virus. American Journal of Obstetrics and Gynecology. 184: 584-90. PMID 11262457 DOI: 10.1067/Mob.2001.111791  0.307
2001 Sobel JD, Ohmit SE, Schuman P, Klein RS, Mayer K, Duerr A, Vazquez JA, Rampalo A. The evolution of Candida species and fluconazole susceptibility among oral and vaginal isolates recovered from human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative women. The Journal of Infectious Diseases. 183: 286-93. PMID 11204125 DOI: 10.1086/317936  0.306
2000 Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. The Journal of Experimental Medicine. 192: 1075-80. PMID 11015448 DOI: 10.1084/Jem.192.7.1075  0.333
2000 Klein RS, Arnsten JH, Sobel JD. Oropharyngeal Candida colonization and human immunodeficiency virus type 1 infection. The Journal of Infectious Diseases. 181: 812-3. PMID 10669393 DOI: 10.1086/315290  0.313
1999 Distabile P, Dubler NN, Solomon L, Klein RS. Self-reported legal needs of women with or at risk for HIV infection. The Her Study Group. Journal of Urban Health : Bulletin of the New York Academy of Medicine. 76: 435-47. PMID 10609593 DOI: 10.1007/Bf02351501  0.324
1999 Cu-Uvin S, Hogan JW, Warren D, Klein RS, Peipert J, Schuman P, Holmberg S, Anderson J, Schoenbaum E, Vlahov D, Mayer KH. Prevalence of lower genital tract infections among human immunodeficiency virus (HIV)-seropositive and high-risk HIV-seronegative women. HIV Epidemiology Research Study Group. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 29: 1145-50. PMID 10524955 DOI: 10.1086/313434  0.332
1999 Klein RS, Flanigan T, Schuman P, Smith D, Vlahov D. Criteria for assessing cutaneous anergy in women with or at risk for HIV infection. HIV Epidemiologic Research Study Group. The Journal of Allergy and Clinical Immunology. 103: 93-8. PMID 9893191 DOI: 10.1016/S0091-6749(99)70531-2  0.305
1998 Schuman P, Sobel JD, Ohmit SE, Mayer KH, Carpenter CC, Rompalo A, Duerr A, Smith DK, Warren D, Klein RS. Mucosal candidal colonization and candidiasis in women with or at risk for human immunodeficiency virus infection. HIV Epidemiology Research Study (HERS) Group. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 27: 1161-7. PMID 9827263 DOI: 10.1086/514979  0.311
1998 Klein RS, Gourevitch MN. Overview of HIV and AIDS: biology and epidemiology of the virus. Gastrointestinal Endoscopy Clinics of North America. 8: 751-67. PMID 9730930 DOI: 10.1016/S1052-5157(18)30230-7  0.354
1998 Small CB, McGowan JP, Klein RS, Schnipper SM, Chang CJ, Rosenstreich DL. Serum IgE levels in patients with human immunodeficiency virus infection. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 81: 75-80. PMID 9690576 DOI: 10.1016/S1081-1206(10)63112-2  0.339
1998 Schuman P, Ohmit SE, Sobel JD, Mayer KH, Greene V, Rompalo A, Klein RS. Oral lesions among women living with or at risk for HIV infection. HIV Epidemiology Research Study (HERS) Group. The American Journal of Medicine. 104: 559-64. PMID 9674719 DOI: 10.1016/S0002-9343(98)00110-7  0.314
1997 Holbrook KA, Klein RS, Hartel D, Elliott DA, Barsky TB, Rothschild LH, Lowy FD. Staphylococcus aureus nasal colonization in HIV-seropositive and HIV-seronegative drug users. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 16: 301-6. PMID 9402078 DOI: 10.1097/00042560-199712010-00012  0.315
1997 Alpert PL, Munsiff SS, Gourevitch MN, Greenberg B, Klein RS. A prospective study of tuberculosis and human immunodeficiency virus infection: clinical manifestations and factors associated with survival. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 24: 661-8. PMID 9145741 DOI: 10.1093/Clind/24.4.661  0.335
1996 Gourevitch MN, Hartel D, Schoenbaum EE, Klein RS. Lack of association of induration size with HIV infection among drug users reacting to tuberculin. American Journal of Respiratory and Critical Care Medicine. 154: 1029-33. PMID 8887602 DOI: 10.1164/Ajrccm.154.4.8887602  0.303
1996 Hershow RC, Galai N, Fukuda K, Graber J, Vlahov D, Rezza G, Klein RS, Des Jarlais DC, Vitek C, Khabbaz R, Freels S, Zuckerman R, Pezzotti P, Kaplan JE. An international collaborative study of the effects of coinfection with human T-lymphotropic virus type II on human immunodeficiency virus type 1 disease progression in injection drug users. The Journal of Infectious Diseases. 174: 309-17. PMID 8699060 DOI: 10.1093/Infdis/174.2.309  0.355
1994 Ho GY, Burk RD, Fleming I, Klein RS. Risk of genital human papillomavirus infection in women with human immunodeficiency virus-induced immunosuppression. International Journal of Cancer. Journal International Du Cancer. 56: 788-92. PMID 8119767 DOI: 10.1002/Ijc.2910560605  0.318
1994 Klein RS, Ho GY, Vermund SH, Fleming I, Burk RD. Risk factors for squamous intraepithelial lesions on Pap smear in women at risk for human immunodeficiency virus infection. The Journal of Infectious Diseases. 170: 1404-9. PMID 7995978 DOI: 10.1093/Infdis/170.6.1404  0.302
1993 Klein RS, Fricker LD. Differential effects of a phorbol ester on carboxypeptidase E in cultured astrocytes and AtT-20 cells, a neuroendocrine cell line. Journal of Neurochemistry. 60: 1615-25. PMID 8473886 DOI: 10.1111/J.1471-4159.1993.Tb13383.X  0.545
1992 Klein RS, Das B, Fricker LD. Secretion of carboxypeptidase E from cultured astrocytes and from AtT-20 cells, a neuroendocrine cell line: implications for neuropeptide biosynthesis. Journal of Neurochemistry. 58: 2011-8. PMID 1573389 DOI: 10.1111/J.1471-4159.1992.Tb10941.X  0.532
1992 Klein RS, Fricker LD. Heterogeneous expression of carboxypeptidase E and proenkephalin mRNAs by cultured astrocytes. Brain Research. 569: 300-10. PMID 1540832 DOI: 10.1016/0006-8993(92)90643-N  0.523
1992 Klein RS, Fricker LD. Cultured astrocytes express mRNA for peptidylglycine-alpha-amidating monooxygenase, a neuropeptide processing enzyme. Brain Research. 596: 202-8. PMID 1467983 DOI: 10.1016/0006-8993(92)91548-S  0.517
1991 Fricker LD, Das B, Klein RS, Greene D, Jung YK. Regulation of carboxypeptidase E (enkephalin convertase). Nida Research Monograph. 111: 171-87. PMID 1775180  0.424
1991 Vermund SH, Kelley KF, Klein RS, Feingold AR, Schreiber K, Munk G, Burk RD. High risk of human papillomavirus infection and cervical squamous intraepithelial lesions among women with symptomatic human immunodeficiency virus infection. American Journal of Obstetrics and Gynecology. 165: 392-400. PMID 1651648 DOI: 10.1016/0002-9378(91)90101-V  0.31
1989 Schoenbaum EE, Hartel D, Selwyn PA, Klein RS, Davenny K, Rogers M, Feiner C, Friedland G. Risk factors for human immunodeficiency virus infection in intravenous drug users. The New England Journal of Medicine. 321: 874-9. PMID 2770823 DOI: 10.1056/NEJM198909283211306  0.31
1989 Klein RS. Prophylaxis of opportunistic infections in individuals infected with HIV. Aids (London, England). 3: S161-73. PMID 2514733 DOI: 10.1097/00002030-198901001-00024  0.323
1988 Antony MA, Brandt LJ, Klein RS, Bernstein LH. Infectious diarrhea in patients with AIDS. Digestive Diseases and Sciences. 33: 1141-6. PMID 3409800 DOI: 10.1007/Bf01535791  0.324
1986 Friedland GH, Saltzman BR, Rogers MF, Kahl PA, Lesser ML, Mayers MM, Klein RS. Lack of transmission of HTLV-III/LAV infection to household contacts of patients with AIDS or AIDS-related complex with oral candidiasis. The New England Journal of Medicine. 314: 344-9. PMID 3456076 DOI: 10.1056/Nejm198602063140604  0.313
1986 Saltzman BR, Motyl MR, Friedland GH, McKitrick JC, Klein RS. Mycobacterium tuberculosis bacteremia in the acquired immunodeficiency syndrome. Jama. 256: 390-1. PMID 3088290 DOI: 10.1001/Jama.1986.03380030092036  0.311
1983 Small CB, Klein RS, Friedland GH, Moll B, Emeson EE, Spigland I. Community-acquired opportunistic infections and defective cellular immunity in heterosexual drug abusers and homosexual men. The American Journal of Medicine. 74: 433-41. PMID 6219579 DOI: 10.1016/0002-9343(83)90970-1  0.354
1982 Moll B, Emeson EE, Small CB, Friedland GH, Klein RS, Spigland I. Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections. Clinical Immunology and Immunopathology. 25: 417-23. PMID 6218947 DOI: 10.1016/0090-1229(82)90206-9  0.305
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