| Year |
Citation |
Score |
| 2023 |
Sagan SA, Moinfar Z, Moseley CE, Dandekar R, Spencer CM, Verkman AS, Ottersen OP, Sobel RA, Sidney J, Sette A, Anderson MS, Steinman L, Wilson MR, Sabatino JJ, Zamvil SS. T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306572120. PMID 37463205 DOI: 10.1073/pnas.2306572120 |
0.311 |
|
| 2020 |
Xiao S, Bod L, Pochet N, Kota SB, Hu D, Madi A, Kilpatrick J, Shi J, Ho A, Zhang H, Sobel R, Weiner HL, Strom TB, Quintana FJ, Joller N, et al. Checkpoint Receptor TIGIT Expressed on Tim-1 B Cells Regulates Tissue Inflammation. Cell Reports. 32: 107892. PMID 32668241 DOI: 10.1016/J.Celrep.2020.107892 |
0.356 |
|
| 2019 |
Sobel RA, Eaton MJ, Jaju PD, Lowry E, Hinojoza JR. Anti-Myelin Proteolipid Protein Peptide Monoclonal Antibodies Recognize Cell Surface Proteins on Developing Neurons and Inhibit Their Differentiation. Journal of Neuropathology and Experimental Neurology. 78: 819-843. PMID 31400116 DOI: 10.1093/Jnen/Nlz058 |
0.349 |
|
| 2019 |
Zhang X, Kiapour N, Kapoor S, Khan T, Thamilarasan M, Tao Y, Cohen S, Miller R, Sobel RA, Markovic-Plese S. IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). PMID 31341075 DOI: 10.4049/Jimmunol.1900311 |
0.331 |
|
| 2019 |
Graham KL, Werner BJ, Moyer KM, Patton AK, Krois CR, Yoo HS, Tverskoy M, LaJevic M, Napoli JL, Sobel RA, Zabel BA, Butcher EC. DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718413 DOI: 10.1073/Pnas.1817669116 |
0.405 |
|
| 2018 |
Meyer Zu Horste G, Przybylski D, Schramm MA, Wang C, Schnell A, Lee Y, Sobel R, Regev A, Kuchroo VK. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 48: 556-569.e7. PMID 29562202 DOI: 10.1016/J.Immuni.2018.03.008 |
0.372 |
|
| 2018 |
Dixon KO, Schorer M, Nevin J, Etminan Y, Amoozgar Z, Kondo T, Kurtulus S, Kassam N, Sobel RA, Fukumura D, Jain RK, Anderson AC, Kuchroo VK, Joller N. Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 29500245 DOI: 10.4049/Jimmunol.1700407 |
0.365 |
|
| 2017 |
Krishnan B, Massilamany C, Basavalingappa RH, Gangaplara A, Rajasekaran RA, Afzal MZ, Khalilzad-Sharghi V, Zhou Y, Riethoven JJ, Nandi SS, Mishra PK, Sobel RA, Strande JL, Steffen D, Reddy J. Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 29229678 DOI: 10.4049/Jimmunol.1701090 |
0.413 |
|
| 2017 |
Sagan SA, Cruz-Herranz A, Spencer CM, Ho PP, Steinman L, Green AJ, Sobel RA, Zamvil SS. Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4. Journal of Visualized Experiments : Jove. PMID 28872108 DOI: 10.3791/56185 |
0.429 |
|
| 2017 |
Cruz-Herranz A, Sagan SA, Sobel RA, Green AJ, Zamvil SS. T cells targeting neuromyelitis optica autoantigen aquaporin-4 cause paralysis and visual system injury. Journal of Nature and Science. 3. PMID 28748216 |
0.3 |
|
| 2016 |
Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, ... Sobel RA, et al. Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940915 DOI: 10.1073/Pnas.1617859114 |
0.435 |
|
| 2016 |
Basavalingappa RH, Massilamany C, Krishnan B, Gangaplara A, Kang G, Khalilzad-Sharghi V, Han Z, Othman S, Li Q, Riethoven JJ, Sobel RA, Steffen D, Reddy J. Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice. The American Journal of Pathology. 186: 3160-3175. PMID 27876151 DOI: 10.1016/J.Ajpath.2016.08.005 |
0.364 |
|
| 2016 |
Varrin-Doyer M, Pekarek KL, Spencer CM, Bernard CC, Sobel RA, Cree BA, Schulze-Topphoff U, Zamvil SS. Treatment of spontaneous EAE by laquinimod reduces Tfh, B cell aggregates, and disease progression. Neurology(R) Neuroimmunology & Neuroinflammation. 3: e272. PMID 27704036 DOI: 10.1212/Nxi.0000000000000272 |
0.354 |
|
| 2016 |
McArdel SL, Brown DR, Sobel RA, Sharpe AH. Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27581174 DOI: 10.4049/Jimmunol.1600706 |
0.308 |
|
| 2016 |
Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL. IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation. Brain : a Journal of Neurology. PMID 27246324 DOI: 10.1093/Brain/Aww113 |
0.405 |
|
| 2016 |
Schulze-Topphoff U, Varrin-Doyer M, Pekarek K, Spencer CM, Shetty A, Sagan SA, Cree BA, Sobel RA, Wipke BT, Steinman L, Scannevin RH, Zamvil SS. Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2. Proceedings of the National Academy of Sciences of the United States of America. PMID 27078105 DOI: 10.1073/Pnas.1603907113 |
0.404 |
|
| 2016 |
Lehmann-Horn K, Sagan SA, Winger RC, Spencer CM, Bernard CC, Sobel RA, Zamvil SS. CNS accumulation of regulatory B cells is VLA-4-dependent. Neurology® Neuroimmunology & Neuroinflammation. 3: e212. PMID 27027096 DOI: 10.1212/Nxi.0000000000000212 |
0.41 |
|
| 2015 |
Wang C, Yosef N, Gaublomme J, Wu C, Lee Y, Clish CB, Kaminski J, Xiao S, Zu Horste GM, Pawlak M, Kishi Y, Joller N, Karwacz K, Zhu C, Ordovas-Montanes M, ... ... Sobel RA, et al. CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity. Cell. PMID 26607793 DOI: 10.1016/J.Cell.2015.10.068 |
0.334 |
|
| 2015 |
Lee Y, Mitsdoerffer M, Xiao S, Gu G, Sobel RA, Kuchroo VK. IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. PMID 26413871 DOI: 10.1172/Jci75933 |
0.337 |
|
| 2015 |
Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH. Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. The Journal of Experimental Medicine. 212: 1603-21. PMID 26371185 DOI: 10.1084/Jem.20141030 |
0.384 |
|
| 2015 |
Lehmann-Horn K, Sagan SA, Bernard CC, Sobel RA, Zamvil SS. B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity. Annals of Neurology. 77: 902-8. PMID 25712734 DOI: 10.1002/Ana.24387 |
0.389 |
|
| 2015 |
Xiao S, Brooks CR, Sobel RA, Kuchroo VK. Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation. Journal of Immunology (Baltimore, Md. : 1950). 194: 1602-8. PMID 25582854 DOI: 10.4049/Jimmunol.1402632 |
0.329 |
|
| 2015 |
Peters A, Burkett PR, Sobel RA, Buckley CD, Watson SP, Bettelli E, Kuchroo VK. Podoplanin negatively regulates CD4+ effector T cell responses. The Journal of Clinical Investigation. 125: 129-40. PMID 25415436 DOI: 10.1172/Jci74685 |
0.403 |
|
| 2014 |
Graham KL, Zhang JV, Lewén S, Burke TM, Dang T, Zoudilova M, Sobel RA, Butcher EC, Zabel BA. A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. Plos One. 9: e112925. PMID 25437209 DOI: 10.1371/Journal.Pone.0112925 |
0.424 |
|
| 2014 |
Shetty A, Gupta SG, Varrin-Doyer M, Weber MS, Prod'homme T, Molnarfi N, Ji N, Nelson PA, Patarroyo JC, Schulze-Topphoff U, Fogal SE, Forsthuber T, Sobel RA, Bernard CC, Slavin AJ, et al. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE. Neurology® Neuroimmunology & Neuroinflammation. 1: e22. PMID 25340074 DOI: 10.1212/Nxi.0000000000000022 |
0.365 |
|
| 2014 |
Massilamany C, Marciano-Cabral F, Rocha-Azevedo Bd, Jamerson M, Gangaplara A, Steffen D, Zabad R, Illes Z, Sobel RA, Reddy J. SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens. Plos One. 9: e98506. PMID 24879066 DOI: 10.1371/Journal.Pone.0098506 |
0.426 |
|
| 2014 |
Wang D, Bhat R, Sobel RA, Huang W, Wang LX, Olsson T, Steinman L. Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Drug Development Research. 75: 172-88. PMID 24648292 DOI: 10.1002/Ddr.21169 |
0.371 |
|
| 2014 |
Varrin-doyer M, Topphoff US, Pekarek K, Sobel RA, Zamvil SS. Laquinimod prevents disability progression in a model of spontaneous chronic EAE and interferes with development of follicular helper T cells Journal of Neuroimmunology. 275: 209. DOI: 10.1016/J.Jneuroim.2014.08.562 |
0.344 |
|
| 2013 |
Molnarfi N, Schulze-Topphoff U, Weber MS, Patarroyo JC, Prod'homme T, Varrin-Doyer M, Shetty A, Linington C, Slavin AJ, Hidalgo J, Jenne DE, Wekerle H, Sobel RA, Bernard CC, Shlomchik MJ, et al. MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. The Journal of Experimental Medicine. 210: 2921-37. PMID 24323356 DOI: 10.1084/Jem.20130699 |
0.414 |
|
| 2013 |
Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, et al. Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nature Immunology. 14: 1166-72. PMID 24076635 DOI: 10.1038/Ni.2730 |
0.33 |
|
| 2013 |
Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Pekarek K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini SE. Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. The Journal of Experimental Medicine. 210: 1301-9. PMID 23797093 DOI: 10.1084/Jem.20121611 |
0.437 |
|
| 2012 |
Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Induction and molecular signature of pathogenic TH17 cells. Nature Immunology. 13: 991-9. PMID 22961052 DOI: 10.1038/Ni.2416 |
0.35 |
|
| 2012 |
Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, et al. Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion. Nature Medicine. 18: 1394-400. PMID 22863785 DOI: 10.1038/Nm.2871 |
0.405 |
|
| 2012 |
Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 12105-10. PMID 22773818 DOI: 10.1073/Pnas.1120914109 |
0.36 |
|
| 2012 |
Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, ... ... Sobel RA, et al. Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. The Journal of Experimental Medicine. 209: 1325-34. PMID 22734047 DOI: 10.1084/Jem.20101974 |
0.367 |
|
| 2012 |
Schulze-Topphoff U, Shetty A, Varrin-Doyer M, Molnarfi N, Sagan SA, Sobel RA, Nelson PA, Zamvil SS. Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity. Plos One. 7: e33797. PMID 22479444 DOI: 10.1371/Journal.Pone.0033797 |
0.451 |
|
| 2012 |
Anderson AC, Chandwaskar R, Lee DH, Sullivan JM, Solomon A, Rodriguez-Manzanet R, Greve B, Sobel RA, Kuchroo VK. A transgenic model of central nervous system autoimmunity mediated by CD4+ and CD8+ T and B cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 2084-92. PMID 22279107 DOI: 10.4049/Jimmunol.1102186 |
0.402 |
|
| 2012 |
Shetty A, Gupta S, Weber M, Molnarfi N, Forsthuber T, Sobel R, Bernard C, Slavin A, Zamvil S. T Cell Epitope 119-132, but Not 35-55, Is the Immunodominant Encephalitogenic Determinant of the CNS Autoantigen, Myelin Oligodendrocyte Glycoprotein (P05.118) Neurology. 78: P05.118-P05.118. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.118 |
0.396 |
|
| 2012 |
Nelson P, Varrin-Doyer M, Spencer C, Sagan S, Boyd C, Sobel R, Bennett J, Zamvil S. Aquaporin-4 Peptide-Specific T Cells Induce CNS Inflammation (P02.134) Neurology. 78: P02.134-P02.134. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.134 |
0.347 |
|
| 2012 |
Schulze Topphoff U, Shetty A, Varrin-Doyer M, Molnarfi N, Sagan S, Sobel R, Nelson P, Zamvil S. Laquinimod Promotes T Cell Immune Modulation in Central Nervous System Autoimmunity Via Type II (M2) Myeloid APC (P02.105) Neurology. 78: P02.105-P02.105. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P02.105 |
0.444 |
|
| 2011 |
Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity. 35: 986-96. PMID 22177922 DOI: 10.1016/J.Immuni.2011.10.015 |
0.4 |
|
| 2011 |
Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH. Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. Journal of Clinical Immunology. 31: 1010-20. PMID 21847523 DOI: 10.1007/S10875-011-9579-6 |
0.378 |
|
| 2010 |
Dunn SE, Bhat R, Straus DS, Sobel RA, Axtell R, Johnson A, Nguyen K, Mukundan L, Moshkova M, Dugas JC, Chawla A, Steinman L. Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. The Journal of Experimental Medicine. 207: 1599-608. PMID 20624891 DOI: 10.1084/Jem.20091663 |
0.386 |
|
| 2010 |
Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, Lee DH, Cornejo M, Nishi N, Yamauchi A, Quintana FJ, Sobel RA, Hirashima M, Kuchroo VK. Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 1383-92. PMID 20574007 DOI: 10.4049/Jimmunol.0903275 |
0.371 |
|
| 2010 |
Kim A, Joseph S, Khan A, Epstein CJ, Sobel R, Huang TT. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radical Biology & Medicine. 48: 1501-12. PMID 20188820 DOI: 10.1016/J.Freeradbiomed.2010.02.028 |
0.312 |
|
| 2009 |
Jäger A, Dardalhon V, Sobel RA, Bettelli E, Kuchroo VK. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. Journal of Immunology (Baltimore, Md. : 1950). 183: 7169-77. PMID 19890056 DOI: 10.4049/Jimmunol.0901906 |
0.403 |
|
| 2009 |
Graham KL, Zabel BA, Loghavi S, Zuniga LA, Ho PP, Sobel RA, Butcher EC. Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease. Journal of Immunology (Baltimore, Md. : 1950). 183: 6717-23. PMID 19864606 DOI: 10.4049/Jimmunol.0803435 |
0.418 |
|
| 2009 |
Araki M, Chung D, Liu S, Rainbow DB, Chamberlain G, Garner V, Hunter KM, Vijayakrishnan L, Peterson LB, Oukka M, Sharpe AH, Sobel R, Kuchroo VK, Wicker LS. Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 5146-57. PMID 19783679 DOI: 10.4049/Jimmunol.0802610 |
0.336 |
|
| 2009 |
Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 14948-53. PMID 19706421 DOI: 10.1073/Pnas.0903958106 |
0.389 |
|
| 2008 |
Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nature Immunology. 9: 1347-55. PMID 18997793 DOI: 10.1038/Ni.1677 |
0.331 |
|
| 2008 |
Rodriguez-Manzanet R, Meyers JH, Balasubramanian S, Slavik J, Kassam N, Dardalhon V, Greenfield EA, Anderson AC, Sobel RA, Hafler DA, Strom TB, Kuchroo VK. TIM-4 expressed on APCs induces T cell expansion and survival. Journal of Immunology (Baltimore, Md. : 1950). 180: 4706-13. PMID 18354194 DOI: 10.4049/Jimmunol.180.7.4706 |
0.37 |
|
| 2008 |
Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 451: 1076-81. PMID 18278032 DOI: 10.1038/Nature06559 |
0.332 |
|
| 2007 |
Illés Z, Waldner H, Reddy J, Anderson AC, Sobel RA, Kuchroo VK. Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background. International Immunology. 19: 1235-48. PMID 17804690 DOI: 10.1093/Intimm/Dxm094 |
0.388 |
|
| 2007 |
Weber MS, Prod'homme T, Youssef S, Dunn SE, Rundle CD, Lee L, Patarroyo JC, Stüve O, Sobel RA, Steinman L, Zamvil SS. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nature Medicine. 13: 935-43. PMID 17676050 DOI: 10.1038/Nm1620 |
0.406 |
|
| 2007 |
Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, et al. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. The Journal of Experimental Medicine. 204: 1691-702. PMID 17606630 DOI: 10.1084/Jem.20062498 |
0.371 |
|
| 2007 |
Greve B, Weissert R, Hamdi N, Bettelli E, Sobel RA, Coyle A, Kuchroo VK, Rajewsky K, Schmidt-Supprian M. I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 179-85. PMID 17579036 DOI: 10.4049/Jimmunol.179.1.179 |
0.424 |
|
| 2007 |
Ousman SS, Tomooka BH, van Noort JM, Wawrousek EF, O'Connor KC, Hafler DA, Sobel RA, Robinson WH, Steinman L. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature. 448: 474-9. PMID 17568699 DOI: 10.1038/Nature05935 |
0.431 |
|
| 2007 |
Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nature Medicine. 13: 423-31. PMID 17384649 DOI: 10.1038/Nm1564 |
0.412 |
|
| 2007 |
Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. The Journal of Experimental Medicine. 204: 321-30. PMID 17261635 DOI: 10.1084/Jem.20061839 |
0.383 |
|
| 2007 |
Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. The Journal of Clinical Investigation. 117: 438-47. PMID 17256058 DOI: 10.1172/Jci28844 |
0.387 |
|
| 2007 |
Sobel RA. Anti-viral T-cell immunity+anti-CNS autoantibody=a model for human acute disseminated encephalomyelitis or multiple sclerosis relapse? The American Journal of Pathology. 170: 436-8. PMID 17255311 DOI: 10.2353/Ajpath.2007.061098 |
0.428 |
|
| 2007 |
Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nature Immunology. 8: 74-83. PMID 17143274 DOI: 10.1038/Ni1415 |
0.395 |
|
| 2007 |
Lee L, Burge M, Ho P, Sobel R, Shizuru J. Purified MHC-Matched Hematopoietic Stem Cell Transplantation Following Total Lymphoid Irradiation and Anti-Thymocyte Globulin (TLI+ATG) Blocks EAE Pathogenesis. Blood. 110: 3259-3259. DOI: 10.1182/Blood.V110.11.3259.3259 |
0.396 |
|
| 2007 |
Manzanet RR, Hartt-Meyers J, Slavik J, Dardalhon V, Kassam N, Greenfield EA, Sobel RA, Strom TB, Hafler DA, Kuchroo VK. Tim-4 Expressed on Antigen-presenting Cells Induces T Cell Expansion and Survival Clinical Immunology. 123: S124-S125. DOI: 10.1016/J.Clim.2007.03.533 |
0.354 |
|
| 2007 |
Dunn S, Ousman S, Sobel R, Baranzini S, Zuniga L, Youssef S, Oksenberg J, Steinman L. Peroxisome Poliferator-activated Receptor-α (PPARα) Expression in T Cells Mediates Gender Differences in Development of T Cell-mediated Autoimmunity Clinical Immunology. 123: S74. DOI: 10.1016/J.Clim.2007.03.390 |
0.343 |
|
| 2007 |
Korn T, Oukka M, Reddy J, Bettelli E, Awasthi A, Sobel R, Wucherpfennig K, Kuchroo V. Myelin-specific Regulatory T Cells Accumulate in the Central Nervous System, but Fail to Suppress Pathogenic Effector T Cells at the Peak of Autoimmune Inflammation Clinical Immunology. 123: S152-S153. DOI: 10.1016/J.Clim.2007.03.073 |
0.402 |
|
| 2006 |
Bettelli E, Baeten D, Jäger A, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. The Journal of Clinical Investigation. 116: 2393-402. PMID 16955141 DOI: 10.1172/Jci28334 |
0.418 |
|
| 2006 |
Waldner H, Sobel RA, Price N, Kuchroo VK. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 5455-62. PMID 16622013 DOI: 10.4049/Jimmunol.176.9.5455 |
0.35 |
|
| 2006 |
Stüve O, Youssef S, Weber MS, Nessler S, von Büdingen HC, Hemmer B, Prod'homme T, Sobel RA, Steinman L, Zamvil SS. Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity. The Journal of Clinical Investigation. 116: 1037-44. PMID 16543951 DOI: 10.1172/Jci25805 |
0.338 |
|
| 2006 |
Greenfield EA, Reddy J, Lees A, Dyer CA, Koul O, Nguyen K, Bell S, Kassam N, Hinojoza J, Eaton MJ, Lees MB, Kuchroo VK, Sobel RA. Monoclonal antibodies to distinct regions of human myelin proteolipid protein simultaneously recognize central nervous system myelin and neurons of many vertebrate species. Journal of Neuroscience Research. 83: 415-31. PMID 16416423 DOI: 10.1002/Jnr.20748 |
0.311 |
|
| 2006 |
Kanter JL, Narayana S, Ho PP, Catz I, Warren KG, Sobel RA, Steinman L, Robinson WH. Lipid microarrays identify key mediators of autoimmune brain inflammation. Nature Medicine. 12: 138-43. PMID 16341241 DOI: 10.1038/Nm1344 |
0.359 |
|
| 2006 |
Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Anderson A, Zhang Z, Gutierrez C, Sobel R, Umetsu D, Yagita H, Akiba H, Sayegh M, DeKruyff R, Khoury S, et al. TIM-1 Plays a Crucial Role in the Expansion of Autopathogneic T-Cells and Regulation of Autoimmunity Clinical Immunology. 119: S44-S45. DOI: 10.1016/J.Clim.2006.04.412 |
0.342 |
|
| 2005 |
Miyamoto K, Kingsley CI, Zhang X, Jabs C, Izikson L, Sobel RA, Weiner HL, Kuchroo VK, Sharpe AH. The ICOS molecule plays a crucial role in the development of mucosal tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 7341-7. PMID 16301640 DOI: 10.4049/Jimmunol.175.11.7341 |
0.41 |
|
| 2005 |
Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science (New York, N.Y.). 310: 850-5. PMID 16272121 DOI: 10.1126/Science.1117634 |
0.403 |
|
| 2005 |
Ho PP, Fontoura P, Platten M, Sobel RA, DeVoss JJ, Lee LY, Kidd BA, Tomooka BH, Capers J, Agrawal A, Gupta R, Zernik J, Yee MK, Lee BJ, Garren H, et al. A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 175: 6226-34. PMID 16237121 DOI: 10.4049/Jimmunol.175.9.6226 |
0.327 |
|
| 2005 |
Reddy J, Waldner H, Zhang X, Illes Z, Wucherpfennig KW, Sobel RA, Kuchroo VK. Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 5591-5. PMID 16237044 DOI: 10.4049/Jimmunol.175.9.5591 |
0.38 |
|
| 2005 |
Zhang Y, Da RR, Hilgenberg LG, Tourtellotte WW, Sobel RA, Smith MA, Olek M, Nagra R, Sudhir G, van den Noort S, Qin Y. Clonal expansion of IgA-positive plasma cells and axon-reactive antibodies in MS lesions. Journal of Neuroimmunology. 167: 120-30. PMID 16099056 DOI: 10.1016/J.Jneuroim.2005.05.006 |
0.314 |
|
| 2005 |
Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, Zheng XX, Strom TB, Kuchroo VK. Tim-2 regulates T helper type 2 responses and autoimmunity. The Journal of Experimental Medicine. 202: 437-44. PMID 16043519 DOI: 10.1084/Jem.20050308 |
0.38 |
|
| 2005 |
Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R, Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. Journal of Immunology (Baltimore, Md. : 1950). 175: 1558-65. PMID 16034094 DOI: 10.4049/Jimmunol.175.3.1558 |
0.332 |
|
| 2005 |
Zhang Y, Da RR, Guo W, Ren HM, Hilgenberg LG, Sobel RA, Tourtellotte WW, Smith MA, Olek M, Gupta S, Robertson RT, Nagra R, Van Den Noort S, Qin Y. Axon reactive B cells clonally expanded in the cerebrospinal fluid of patients with multiple sclerosis. Journal of Clinical Immunology. 25: 254-64. PMID 15981091 DOI: 10.1007/S10875-005-4083-5 |
0.311 |
|
| 2004 |
Fontoura P, Ho PP, DeVoss J, Zheng B, Lee BJ, Kidd BA, Garren H, Sobel RA, Robinson WH, Tessier-Lavigne M, Steinman L. Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 6981-92. PMID 15557195 DOI: 10.4049/Jimmunol.173.11.6981 |
0.394 |
|
| 2004 |
Reddy J, Illes Z, Zhang X, Encinas J, Pyrdol J, Nicholson L, Sobel RA, Wucherpfennig KW, Kuchroo VK. Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 101: 15434-9. PMID 15492218 DOI: 10.1073/Pnas.0404444101 |
0.368 |
|
| 2004 |
Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, Klemm M, Kuchroo VK, Freeman GJ, Sharpe AH. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 10691-6. PMID 15249675 DOI: 10.1073/Pnas.0307252101 |
0.309 |
|
| 2004 |
Anderson AC, Reddy J, Nazareno R, Sobel RA, Nicholson LB, Kuchroo VK. IL-10 plays an important role in the homeostatic regulation of the autoreactive repertoire in naive mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 828-34. PMID 15240669 DOI: 10.4049/Jimmunol.173.2.828 |
0.407 |
|
| 2004 |
Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 200: 79-87. PMID 15238607 DOI: 10.1084/Jem.20031819 |
0.414 |
|
| 2004 |
Greve B, Reddy J, Waldner HP, Sobel RA, Kuchroo VK. Dissimilar background genes control susceptibility to autoimmune disease in the context of different MHC haplotypes: NOD.H-2(s) congenic mice are relatively resistant to both experimental autoimmune encephalomyelitis and type I diabetes. European Journal of Immunology. 34: 1828-38. PMID 15214031 DOI: 10.1002/Eji.200425116 |
0.365 |
|
| 2004 |
Greve B, Vijayakrishnan L, Kubal A, Sobel RA, Peterson LB, Wicker LS, Kuchroo VK. The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 157-63. PMID 15210770 DOI: 10.4049/Jimmunol.173.1.157 |
0.376 |
|
| 2004 |
Maffei CM, Mirels LF, Sobel RA, Clemons KV, Stevens DA. Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis. Infection and Immunity. 72: 2338-49. PMID 15039359 DOI: 10.1128/Iai.72.4.2338-2349.2004 |
0.326 |
|
| 2004 |
Klein RS, Izikson L, Means T, Gibson HD, Lin E, Sobel RA, Weiner HL, Luster AD. IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 172: 550-9. PMID 14688366 DOI: 10.4049/Jimmunol.172.1.550 |
0.432 |
|
| 2003 |
Chang TT, Sobel RA, Wei T, Ransohoff RM, Kuchroo VK, Sharpe AH. Recovery from EAE is associated with decreased survival of encephalitogenic T cells in the CNS of B7-1/B7-2-deficient mice. European Journal of Immunology. 33: 2022-2032. PMID 12884869 DOI: 10.1002/Eji.200323180 |
0.369 |
|
| 2003 |
Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of Experimental Medicine. 197: 1073-81. PMID 12732654 DOI: 10.1084/Jem.20021603 |
0.38 |
|
| 2003 |
Pedotti R, DeVoss JJ, Youssef S, Mitchell D, Wedemeyer J, Madanat R, Garren H, Fontoura P, Tsai M, Galli SJ, Sobel RA, Steinman L. Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proceedings of the National Academy of Sciences of the United States of America. 100: 1867-72. PMID 12576552 DOI: 10.1073/Pnas.252777399 |
0.386 |
|
| 2003 |
Kamberi P, Sobel RA, Clemons KV, Stevens DA, Pappagianis D, Williams PL. A murine model of coccidioidal meningitis. The Journal of Infectious Diseases. 187: 453-60. PMID 12552429 DOI: 10.1086/367961 |
0.304 |
|
| 2002 |
Youssef S, Stüve O, Patarroyo JC, Ruiz PJ, Radosevich JL, Hur EM, Bravo M, Mitchell DJ, Sobel RA, Steinman L, Zamvil SS. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 420: 78-84. PMID 12422218 DOI: 10.1038/Nature01158 |
0.396 |
|
| 2002 |
Jabs C, Greve B, Chang TT, Sobel RA, Sharpe AH, Kuchroo VK. Genetic background determines the requirement for B7 costimulation in induction of autoimmunity. European Journal of Immunology. 32: 2687-97. PMID 12207354 DOI: 10.1002/1521-4141(200209)32:9<2687::Aid-Immu2687>3.0.Co;2-1 |
0.322 |
|
| 2002 |
Chiller TM, Luque JC, Sobel RA, Farrokhshad K, Clemons KV, Stevens DA. Development of a murine model of cerebral aspergillosis. The Journal of Infectious Diseases. 186: 574-7. PMID 12195389 DOI: 10.1086/341567 |
0.334 |
|
| 2002 |
Kuruganti PA, Hinojoza JR, Eaton MJ, Ehmann UK, Sobel RA. Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules-implications for multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 61: 710-24. PMID 12152786 DOI: 10.1093/Jnen/61.8.710 |
0.332 |
|
| 2002 |
Hurwitz AA, Sullivan TJ, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 3013-7. PMID 11867713 DOI: 10.1073/Pnas.042684699 |
0.42 |
|
| 2002 |
Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 415: 536-41. PMID 11823861 DOI: 10.1038/415536A |
0.391 |
|
| 2001 |
Sobel RA, Ahmed AS. White matter extracellular matrix chondroitin sulfate/dermatan sulfate proteoglycans in multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 60: 1198-207. PMID 11764092 DOI: 10.1093/Jnen/60.12.1198 |
0.326 |
|
| 2001 |
Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (New York, N.Y.). 294: 1731-5. PMID 11721059 DOI: 10.1126/Science.1062960 |
0.405 |
|
| 2001 |
Greer JM, Denis B, Sobel RA, Trifilieff E. Thiopalmitoylation of myelin proteolipid protein epitopes enhances immunogenicity and encephalitogenicity. Journal of Immunology (Baltimore, Md. : 1950). 166: 6907-13. PMID 11359852 DOI: 10.4049/Jimmunol.166.11.6907 |
0.362 |
|
| 2001 |
Encinas JA, Lees MB, Sobel RA, Symonowicz C, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK. Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis. International Immunology. 13: 257-64. PMID 11222494 DOI: 10.1093/Intimm/13.3.257 |
0.312 |
|
| 2000 |
Clemons KV, Grunig G, Sobel RA, Mirels LF, Rennick DM, Stevens DA. Role of IL-10 in invasive aspergillosis: increased resistance of IL-10 gene knockout mice to lethal systemic aspergillosis. Clinical and Experimental Immunology. 122: 186-91. PMID 11091273 DOI: 10.1046/J.1365-2249.2000.01382.X |
0.302 |
|
| 2000 |
Kuhns MS, Epshteyn V, Sobel RA, Allison JP. Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 12711-6. PMID 11050166 DOI: 10.1073/Pnas.220423597 |
0.387 |
|
| 2000 |
Clemons KV, Darbonne WC, Curnutte JT, Sobel RA, Stevens DA. Experimental histoplasmosis in mice treated with anti-murine interferon-gamma antibody and in interferon-gamma gene knockout mice. Microbes and Infection / Institut Pasteur. 2: 997-1001. PMID 10967280 DOI: 10.1016/S1286-4579(00)01253-3 |
0.317 |
|
| 2000 |
Sobel RA. Genetic and epigenetic influence on EAE phenotypes induced with different encephalitogenic peptides. Journal of Neuroimmunology. 108: 45-52. PMID 10900336 DOI: 10.1016/S0165-5728(99)00270-2 |
0.336 |
|
| 2000 |
Waldner H, Whitters MJ, Sobel RA, Collins M, Kuchroo VK. Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 3412-7. PMID 10737797 DOI: 10.1073/Pnas.97.7.3412 |
0.422 |
|
| 2000 |
Smith-Norowitz TA, Sobel RA, Mokhtarian F. B cells and antibodies in the pathogenesis of myelin injury in Semliki Forest Virus encephalomyelitis. Cellular Immunology. 200: 27-35. PMID 10716880 DOI: 10.1006/Cimm.2000.1613 |
0.382 |
|
| 1999 |
Chang TT, Jabs C, Sobel RA, Kuchroo VK, Sharpe AH. Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 190: 733-40. PMID 10477557 DOI: 10.1084/Jem.190.5.733 |
0.392 |
|
| 1999 |
Adler H, Beland JL, Del-Pan NC, Kobzik L, Sobel RA, Rimm IJ. In the absence of T cells, natural killer cells protect from mortality due to HSV-1 encephalitis. Journal of Neuroimmunology. 93: 208-13. PMID 10378885 DOI: 10.1016/S0165-5728(98)00236-7 |
0.377 |
|
| 1999 |
Beland JL, Sobel RA, Adler H, Del-Pan NC, Rimm IJ. B cell-deficient mice have increased susceptibility to HSV-1 encephalomyelitis and mortality. Journal of Neuroimmunology. 94: 122-6. PMID 10376944 DOI: 10.1016/S0165-5728(98)00238-0 |
0.35 |
|
| 1999 |
Mokhtarian F, Zhang Z, Shi Y, Gonzales E, Sobel RA. Molecular mimicry between a viral peptide and a myelin oligodendrocyte glycoprotein peptide induces autoimmune demyelinating disease in mice. Journal of Neuroimmunology. 95: 43-54. PMID 10229114 DOI: 10.1016/S0165-5728(98)00254-9 |
0.348 |
|
| 1999 |
van der Maesen K, Hinojoza JR, Sobel RA. Endothelial cell class II major histocompatibility complex molecule expression in stereotactic brain biopsies of patients with acute inflammatory/demyelinating conditions. Journal of Neuropathology and Experimental Neurology. 58: 346-58. PMID 10218630 DOI: 10.1097/00005072-199904000-00005 |
0.337 |
|
| 1998 |
Carrizosa AM, Nicholson LB, Farzan M, Southwood S, Sette A, Sobel RA, Kuchroo VK. Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen. Journal of Immunology (Baltimore, Md. : 1950). 161: 3307-14. PMID 9759846 DOI: 10.1016/S0165-5728(98)91376-5 |
0.368 |
|
| 1998 |
Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 161: 3299-306. PMID 9759845 DOI: 10.1016/S0165-5728(98)91500-4 |
0.313 |
|
| 1998 |
Sobel RA. The extracellular matrix in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 57: 205-17. PMID 9600212 DOI: 10.1097/00005072-199803000-00001 |
0.325 |
|
| 1998 |
Santambrogio L, Lees MB, Sobel RA. Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS. Journal of Neuroimmunology. 81: 1-13. PMID 9521600 DOI: 10.1016/S0165-5728(97)00138-0 |
0.396 |
|
| 1998 |
Smith ME, van der Maesen K, Somera FP, Sobel RA. Effects of phorbol myristate acetate (PMA) on functions of macrophages and microglia in vitro. Neurochemical Research. 23: 427-34. PMID 9482257 DOI: 10.1023/A:1022478005243 |
0.318 |
|
| 1998 |
Mokhtarian F, Sobel R, Zhang Z, Shi Y, Gonzales E. Molecular mimicry between a viral peptide and a myelin peptide induced autoimmune demyelinating disease in mice Journal of Neuroimmunology. 90: 36. DOI: 10.1016/S0165-5728(98)91394-7 |
0.309 |
|
| 1997 |
Gilles FH, Sobel EL, Leviton A, Tavaré CJ, Hedley-Whyte ET, Rorke L, Adelman L, Sobel R. Quantitative histologic factors for grouping childhood infratentorial neuroglial tumors. Pediatric Pathology & Laboratory Medicine : Journal of the Society For Pediatric Pathology, Affiliated With the International Paediatric Pathology Association. 17: 809-34. PMID 9267891 DOI: 10.1080/107710497174499 |
0.43 |
|
| 1997 |
Greer JM, Klinguer C, Trifilieff E, Sobel RA, Lees MB. Encephalitogenicity of murine, but not bovine, DM20 in SJL mice is due to a single amino acid difference in the immunodominant encephalitogenic epitope. Neurochemical Research. 22: 541-7. PMID 9130268 DOI: 10.1023/A:1027336516785 |
0.34 |
|
| 1997 |
Hurwitz AA, Sullivan TJ, Krummel MF, Sobel RA, Allison JP. Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. Journal of Neuroimmunology. 73: 57-62. PMID 9058759 DOI: 10.1016/S0165-5728(96)00168-3 |
0.352 |
|
| 1996 |
Mokhtarian F, Wesselingh SL, Choi S, Maeda A, Griffin DE, Sobel RA, Grob D. Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis. Journal of Neuroimmunology. 66: 11-22. PMID 8964904 DOI: 10.1016/0165-5728(95)00181-6 |
0.362 |
|
| 1996 |
al-Sabbagh A, Nelson PA, Akselband Y, Sobel RA, Weiner HL. Antigen-driven peripheral immune tolerance: suppression of experimental autoimmmune encephalomyelitis and collagen-induced arthritis by aerosol administration of myelin basic protein or type II collagen. Cellular Immunology. 171: 111-9. PMID 8660845 DOI: 10.1006/Cimm.1996.0180 |
0.375 |
|
| 1995 |
Sobel RA. The pathology of multiple sclerosis. Neurologic Clinics. 13: 1-21. PMID 7739499 DOI: 10.1016/S0733-8619(18)30059-8 |
0.355 |
|
| 1995 |
Nicholson LB, Greer JM, Sobel RA, Lees MB, Kuchroo VK. An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis. Immunity. 3: 397-405. PMID 7584131 DOI: 10.1016/1074-7613(95)90169-8 |
0.369 |
|
| 1995 |
Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80: 707-18. PMID 7534215 DOI: 10.1016/0092-8674(95)90349-6 |
0.356 |
|
| 1995 |
Sobel RA, Chen M, Maeda A, Hinojoza JR. Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 54: 202-13. PMID 7533209 DOI: 10.1097/00005072-199503000-00007 |
0.325 |
|
| 1994 |
Kuchroo VK, Collins M, al-Sabbagh A, Sobel RA, Whitters MJ, Zamvil SS, Dorf ME, Hafler DA, Seidman JG, Weiner HL. T cell receptor (TCR) usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with TCR V beta 8.2 transgenic mice. The Journal of Experimental Medicine. 179: 1659-64. PMID 8163944 DOI: 10.1084/Jem.179.5.1659 |
0.433 |
|
| 1994 |
Sobel RA, Greer JM, Kuchroo VK. Minireview: autoimmune responses to myelin proteolipid protein. Neurochemical Research. 19: 915-21. PMID 7528354 DOI: 10.1007/Bf00968701 |
0.373 |
|
| 1993 |
Centeno BA, Louis DN, Kupsky WJ, Preffer FI, Sobel RA. The AgNOR technique, PCNA immunohistochemistry, and DNA ploidy in the evaluation of choroid plexus biopsy specimens. American Journal of Clinical Pathology. 100: 690-6. PMID 7902669 DOI: 10.1093/Ajcp/100.6.690 |
0.45 |
|
| 1993 |
Miller A, Zhang ZJ, Sobel RA, al-Sabbagh A, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. VI. Suppression of adoptively transferred disease and differential effects of oral vs. intravenous tolerization. Journal of Neuroimmunology. 46: 73-82. PMID 7689596 DOI: 10.1016/0165-5728(93)90235-Q |
0.352 |
|
| 1993 |
Abromson-Leeman S, Hayashi M, Martin C, Sobel R, al-Sabbagh A, Weiner H, Dorf ME. T cell responses to myelin basic protein in experimental autoimmune encephalomyelitis-resistant BALB/c mice. Journal of Neuroimmunology. 45: 89-101. PMID 7687253 DOI: 10.1016/0165-5728(93)90168-X |
0.433 |
|
| 1993 |
Greer J, Kuchroo V, Sobel R, Lees M. A second encephalitogenic PLP epitope for SJL mice Journal of Neuroimmunology. 43: 206. DOI: 10.1016/0165-5728(93)90108-B |
0.308 |
|
| 1992 |
Gilles FH, Sobel E, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman LS, Sobel RA. Epidemiology of seizures in children with brain tumors. The Childhood Brain Tumor Consortium. Journal of Neuro-Oncology. 12: 53-68. PMID 1541979 DOI: 10.1007/Bf00172457 |
0.476 |
|
| 1992 |
Gilles FH, Sobel EL, Leviton A, Hedley-Whyte ET, Tavare CJ, Adelman L, Sobel RA. Temporal trends among childhood brain tumor biopsies. The Childhood Brain Tumor Consortium. Journal of Neuro-Oncology. 13: 137-49. PMID 1432031 DOI: 10.1007/Bf00172763 |
0.493 |
|
| 1992 |
Tuohy VK, Sobel RA, Lu Z, Laursen RA, Lees MB. Myelin proteolipid protein: minimum sequence requirements for active induction of autoimmune encephalomyelitis in SWR/J and SJL/J mice. Journal of Neuroimmunology. 39: 67-74. PMID 1377711 DOI: 10.1016/0165-5728(92)90175-K |
0.344 |
|
| 1991 |
Zamaroczy D, Schluesener HJ, Jolesz FA, Sobel RA, Colucci VM, Weiner HL, Sandor T. Differentiation of experimental white matter lesions using multiparametric magnetic resonance measurements. Investigative Radiology. 26: 317-24. PMID 2032819 DOI: 10.1097/00004424-199104000-00007 |
0.321 |
|
| 1991 |
Louis DN, Hamilton AJ, Sobel RA, Ojemann RG. Pseudopsammomatous meningioma with elevated serum carcinoembryonic antigen: a true secretory meningioma. Case report. Journal of Neurosurgery. 74: 129-32. PMID 1984492 DOI: 10.3171/Jns.1991.74.1.0129 |
0.463 |
|
| 1991 |
Weiner HL, Zhang ZJ, Khoury SJ, Miller A, al-Sabbagh A, Brod SA, Lider O, Higgins P, Sobel R, Nussenblatt RB. Antigen-driven peripheral immune tolerance. Suppression of organ-specific autoimmune diseases by oral administration of autoantigens. Annals of the New York Academy of Sciences. 636: 227-32. PMID 1793212 DOI: 10.1111/J.1749-6632.1991.Tb33454.X |
0.309 |
|
| 1991 |
Kuchroo VK, Sobel RA, Yamamura T, Greenfield E, Dorf ME, Lees MB. Induction of experimental allergic encephalomyelitis by myelin proteolipid-protein-specific T cell clones and synthetic peptides. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 59: 305-12. PMID 1716908 DOI: 10.1159/000163668 |
0.362 |
|
| 1991 |
Brod SA, al-Sabbagh A, Sobel RA, Hafler DA, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin antigens: IV. Suppression of chronic relapsing disease in the Lewis rat and strain 13 guinea pig. Annals of Neurology. 29: 615-22. PMID 1716432 DOI: 10.1002/Ana.410290608 |
0.358 |
|
| 1991 |
Kuchroo VK, Sobel RA, Laning JC, Greenfield E, Ju S, Dorf ME, Lees MB. Heterogeneity of T cell clones specific for an encephalitogenic determinant of myelin proteolipid protein (PLP) Journal of Neuroimmunology. 35: 44. DOI: 10.1016/0165-5728(91)90913-R |
0.366 |
|
| 1991 |
Sobel RA, Kuchroo VK, Wang Y, Dorf ME, Lees MB. Heterogeneous T cell receptor (TcR) Vβs of acute experimental allergic encephalomyelitis (EAE) induced with a myelin proteolipid protein (PLP) peptide and peptide-specific T cell clones Journal of Neuroimmunology. 35: 43. DOI: 10.1016/0165-5728(91)90912-Q |
0.359 |
|
| 1990 |
Sobel RA, Tuohy VK, Lu ZJ, Laursen RA, Lees MB. Acute experimental allergic encephalomyelitis in SJL/J mice induced by a synthetic peptide of myelin proteolipid protein. Journal of Neuropathology and Experimental Neurology. 49: 468-79. PMID 2273404 DOI: 10.1097/00005072-199009000-00002 |
0.367 |
|
| 1990 |
Lampson LA, Kushner PD, Sobel RA. Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Annals of Neurology. 28: 365-72. PMID 2241118 DOI: 10.1002/Ana.410280311 |
0.36 |
|
| 1989 |
Sobel RA. T-lymphocyte subsets in the multiple sclerosis lesion. Research in Immunology. 140: 208-11; discussion 2. PMID 2500682 DOI: 10.1016/0923-2494(89)90088-6 |
0.327 |
|
| 1989 |
Schluesener HJ, Lider O, Sobel RA. Induction of hyperacute brain inflammation and demyelination by activated encephalitogenic T cells and a monoclonal antibody specific for a myelin/oligodendrocyte glycoprotein. Autoimmunity. 2: 265-73. PMID 2491610 DOI: 10.3109/08916938909014690 |
0.387 |
|
| 1988 |
Sobel RA, Ames MB. Major histocompatibility complex molecule expression in the human central nervous system: immunohistochemical analysis of 40 patients. Journal of Neuropathology and Experimental Neurology. 47: 19-28. PMID 3119782 DOI: 10.1097/00005072-198801000-00003 |
0.319 |
|
| 1988 |
Sobel RA, Hafler DA, Castro EE, Morimoto C, Weiner HL. Immunohistochemical analysis of suppressor-inducer and helper-inducer T cells in multiple sclerosis brain tissue. Annals of the New York Academy of Sciences. 540: 306-8. PMID 2905121 DOI: 10.1016/0165-5728(87)90382-1 |
0.36 |
|
| 1988 |
Schluesener HJ, Sobel RA, Weiner HL. Demyelinating experimental allergic encephalomyelitis (EAE) in the rat: treatment with a monoclonal antibody against activated T cells. Journal of Neuroimmunology. 18: 341-51. PMID 2454946 DOI: 10.1016/0165-5728(88)90055-0 |
0.361 |
|
| 1987 |
Sobel RA, Natale JM, Schneeberger EE. The immunopathology of acute experimental allergic encephalomyelitis. IV. An ultrastructural immunocytochemical study of class II major histocompatibility complex molecule (Ia) expression. Journal of Neuropathology and Experimental Neurology. 46: 239-49. PMID 3549982 DOI: 10.1097/00005072-198705000-00001 |
0.376 |
|
| 1987 |
Scott CF, Lambert JM, Goldmacher VS, Blatter WA, Sobel R, Schlossman SF, Benacerraf B. The pharmacokinetics and toxicity of murine monoclonal antibodies and of gelonin conjugates of these antibodies. International Journal of Immunopharmacology. 9: 211-25. PMID 3495503 DOI: 10.1016/0192-0561(87)90096-8 |
0.322 |
|
| 1987 |
McKee AC, Lewandrowski KB, Sobel RA. THE NEUROPATHOLOGY OF THE SMITH-LEMLI-OPITZ SYNDROME–CASE REPORT Journal of Neuropathology and Experimental Neurology. 46: 386. DOI: 10.1097/00005072-198705000-00169 |
0.363 |
|
| 1987 |
Tuohy V, Sobel R, Lees M. EAE induced by myelin proteolipid apoprotein (PLP) in various strains of mice Journal of Neuroimmunology. 16: 174. DOI: 10.1016/0165-5728(87)90400-0 |
0.31 |
|
| 1986 |
Yankner BA, Skolnik PR, Shoukimas GM, Gabuzda DH, Sobel RA, Ho DD. Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system. Annals of Neurology. 20: 362-4. PMID 3639720 DOI: 10.1002/Ana.410200316 |
0.303 |
|
| 1986 |
Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Rota TR, Sobel RA. Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Annals of Neurology. 20: 289-95. PMID 3532930 DOI: 10.1002/Ana.410200304 |
0.309 |
|
| 1986 |
van der Veen RC, Sobel RA, Lees MB. Chronic experimental allergic encephalomyelitis and antibody responses in rabbits immunized with bovine proteolipid apoprotein. Journal of Neuroimmunology. 11: 321-33. PMID 2423554 DOI: 10.1016/0165-5728(86)90085-8 |
0.323 |
|
| 1984 |
Sobel RA, Blanchette BW, Colvin RB. 97 CHRONIC EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (cEAE) FOLLOWS ANTI-T CELL MONOCLONAL ANTIBODY MODULATION OF ACUTE F.AE (aEAE) IN ADULT GUINEA PIGS (GP) Journal of Neuropathology and Experimental Neurology. 43: 325. DOI: 10.1097/00005072-198405000-00106 |
0.302 |
|
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