Christopher P. Ptak, Ph.D. - Publications

Affiliations: 
2005 University of Virginia, Charlottesville, VA 
Area:
General Biophysics

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ptak CP, Peterson TA, Hopkins JB, Ahern CA, Shy ME, Piper RC. Homomeric interactions of the MPZ Ig domain and their relation to Charcot-Marie-Tooth disease. Brain : a Journal of Neurology. PMID 37542466 DOI: 10.1093/brain/awad258  0.307
2019 Yuan CL, Shi EY, Srinivasan J, Ptak CP, Oswald RE, Nowak LM. Modulation of AMPA Receptor Gating by the Anticonvulsant Drug, Perampanel. Acs Medicinal Chemistry Letters. 10: 237-242. PMID 30891119 DOI: 10.1021/Acsmedchemlett.8B00322  0.37
2019 Shi EY, Yuan CL, Sipple MT, Srinivasan J, Ptak CP, Oswald RE, Nowak LM. Noncompetitive antagonists induce cooperative AMPA receptor channel gating. The Journal of General Physiology. PMID 30622133 DOI: 10.1085/Jgp.201812209  0.448
2018 Ptak CP, Akif M, Hsieh CL, Devarajan A, He P, Xu Y, Oswald RE, Chang YF. Comparative screening of recombinant antigen thermostability for improved leptospirosis vaccine design. Biotechnology and Bioengineering. PMID 30418677 DOI: 10.1002/Bit.26864  0.382
2017 Goffin E, Drapier T, Larsen AP, Geubelle P, Ptak CP, Laulumaa S, Rovinskaja K, Gilissen J, Tullio P, Olsen L, Frydenvang K, Pirotte B, Hanson J, Oswald RE, Kastrup JS, et al. 7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. Journal of Medicinal Chemistry. PMID 29256599 DOI: 10.1021/Acs.Jmedchem.7B01323  0.369
2017 Hsieh CL, Ptak CP, Tseng A, Suguiura IMS, McDonough SP, Sritrakul T, Li T, Lin YP, Gillilan RE, Oswald R, Chang YF. Extended low-resolution structure of a Leptospira antigen offers high bactericidal antibody accessibility amenable to vaccine design. Elife. 6. PMID 29210669 DOI: 10.7554/Elife.30051  0.364
2016 Hsieh CL, Chang E, Tseng A, Ptak C, Wu LC, Su CL, McDonough SP, Lin YP, Chang YF. Leptospira Immunoglobulin-Like Protein B (LigB) Binds to Both the C-Terminal 23 Amino Acids of Fibrinogen αC Domain and Factor XIII: Insight into the Mechanism of LigB-Mediated Blockage of Fibrinogen α Chain Cross-Linking. Plos Neglected Tropical Diseases. 10: e0004974. PMID 27622634 DOI: 10.1371/Journal.Pntd.0004974  0.43
2016 Ptak CP, Ahmed AH, Oswald RE. Sensing Allosteric Modulator Binding to AMPA Receptors at the Glutamate-Binding Site Biophysical Journal. 110: 201a. DOI: 10.1016/J.Bpj.2015.11.1122  0.463
2015 Oswald RE, Ahmed AH, Ptak CP, Martinez M. AMPA Receptor Structure, Function, and Dynamics Biophysical Journal. 108: 335a-336a. DOI: 10.1016/J.Bpj.2014.11.1830  0.506
2014 Ptak CP, Hsieh CL, Lin YP, Maltsev AS, Raman R, Sharma Y, Oswald RE, Chang YF. NMR solution structure of the terminal immunoglobulin-like domain from the leptospira host-interacting outer membrane protein, LigB. Biochemistry. 53: 5249-60. PMID 25068811 DOI: 10.1021/Bi500669U  0.449
2014 Ptak CP, Hsieh CL, Weiland GA, Oswald RE. Role of stoichiometry in the dimer-stabilizing effect of AMPA receptor allosteric modulators. Acs Chemical Biology. 9: 128-33. PMID 24152170 DOI: 10.1021/Cb4007166  0.486
2013 Ahmed AH, Ptak CP, Fenwick MK, Hsieh CL, Weiland GA, Oswald RE. Dynamics of cleft closure of the GluA2 ligand-binding domain in the presence of full and partial agonists revealed by hydrogen-deuterium exchange. The Journal of Biological Chemistry. 288: 27658-66. PMID 23940029 DOI: 10.1074/Jbc.M113.495564  0.447
2013 Raman R, Ptak CP, Hsieh CL, Oswald RE, Chang YF, Sharma Y. The perturbation of tryptophan fluorescence by phenylalanine to alanine mutations identifies the hydrophobic core in a subset of bacterial Ig-like domains. Biochemistry. 52: 4589-91. PMID 23800025 DOI: 10.1021/Bi400128R  0.456
2013 Kuo CJ, Ptak CP, Hsieh CL, Akey BL, Chang YF. Elastin, a novel extracellular matrix protein adhering to mycobacterial antigen 85 complex. The Journal of Biological Chemistry. 288: 3886-96. PMID 23250738 DOI: 10.1074/Jbc.M112.415679  0.369
2013 Hsieh CL, Ptak CP, Maltsev AS, Oswald RE, Fu Chang Y. Structural Architecture of the Multi-Immunoglobulin-Like Domain Chain from Ligb Biophysical Journal. 104: 568a. DOI: 10.1016/J.Bpj.2012.11.3151  0.465
2013 Ptak CP, Healy LE, Hsieh CL, Oswald RE. Biophysical Studies on Glua2 Ligand-Binding Domain Dimerization in Solution Biophysical Journal. 104: 272a. DOI: 10.1016/J.Bpj.2012.11.1528  0.496
2012 Kuo CJ, Bell H, Hsieh CL, Ptak CP, Chang YF. Novel mycobacteria antigen 85 complex binding motif on fibronectin. The Journal of Biological Chemistry. 287: 1892-902. PMID 22128161 DOI: 10.1074/Jbc.M111.298687  0.425
2010 Ahmed AH, Ptak CP, Oswald RE. Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA. Biochemistry. 49: 2843-50. PMID 20199107 DOI: 10.1021/Bi1000678  0.43
2010 Ptak CP, Ahmed AH, Fenwick MK, Maltsev A, Oswald RE. Exploring the Role of Positive Allosteric Modulators in Stabilizing the GluR2 Ligand-Binding Domain Dimer Biophysical Journal. 98: 609a. DOI: 10.1016/J.Bpj.2009.12.3323  0.522
2009 Ptak CP, Ahmed AH, Oswald RE. Probing the allosteric modulator binding site of GluR2 with thiazide derivatives. Biochemistry. 48: 8594-602. PMID 19673491 DOI: 10.1021/Bi901127S  0.483
2005 Ptak CP, Cuello LG, Perozo E. Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces. Biochemistry. 44: 62-71. PMID 15628846 DOI: 10.1021/Bi048390F  0.549
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