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Eduardo Perozo - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Ion channels
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183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lau CHY, Flood E, Hunter MJ, Williams-Noonan BJ, Corbett KM, Ng CA, Bouwer JC, Stewart AG, Perozo E, Allen TW, Vandenberg JI. Potassium dependent structural changes in the selectivity filter of HERG potassium channels. Nature Communications. 15: 7470. PMID 39209832 DOI: 10.1038/s41467-024-51208-w  0.49
2023 Lin X, Haller PR, Bavi N, Faruk N, Perozo E, Sosnick TR. Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility. Elife. 12. PMID 38054956 DOI: 10.7554/eLife.89635  0.695
2023 Shen R, Roux B, Perozo E. Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP. The Journal of General Physiology. 156. PMID 38019193 DOI: 10.1085/jgp.202213311  0.645
2023 Erramilli SK, Dominik PK, Deneka D, Tokarz P, Kim SS, Reddy BG, Skrobek BM, Dalmas O, Perozo E, Kossiakoff AA. Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA. Journal of Molecular Biology. 168192. PMID 37394032 DOI: 10.1016/j.jmb.2023.168192  0.857
2023 Erramilli SK, Dominik PK, Deneka D, Tokarz P, Kim SS, Reddy BG, Skrobek BM, Dalmas O, Perozo E, Kossiakoff AA. Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA. Biorxiv : the Preprint Server For Biology. PMID 37205530 DOI: 10.1101/2023.05.07.539746  0.857
2023 Lin X, Haller P, Bavi N, Faruk N, Perozo E, Sosnick TR. Folding of Prestin's Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility. Biorxiv : the Preprint Server For Biology. PMID 36909622 DOI: 10.1101/2023.02.27.530320  0.682
2023 Park YC, Reddy B, Bavi N, Perozo E, Faraldo-Gómez JD. State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels. Elife. 12. PMID 36715097 DOI: 10.7554/eLife.81445  0.856
2022 Shen R, Meng Y, Roux B, Perozo E. Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206649119. PMID 36279472 DOI: 10.1073/pnas.2206649119  0.66
2022 Carrasquel-Ursulaez W, Segura I, Díaz-Franulic I, Echeverría F, Lorenzo-Ceballos Y, Espinoza N, Rojas M, Garate JA, Perozo E, Alvarez O, Gonzalez-Nilo FD, Latorre R. Mechanism of voltage sensing in Ca- and voltage-activated K (BK) channels. Proceedings of the National Academy of Sciences of the United States of America. 119: e2204620119. PMID 35704760 DOI: 10.1073/pnas.2204620119  0.609
2022 Zhao R, Shen R, Dai H, Perozo E, Goldstein SAN. Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120750119. PMID 35648818 DOI: 10.1073/pnas.2120750119  0.595
2021 Bavi N, Clark MD, Contreras GF, Shen R, Reddy BG, Milewski W, Perozo E. Prestin's conformational cycle underlies outer hair cell electromotility. Nature. PMID 34695838 DOI: 10.1038/s41586-021-04152-4  0.811
2021 Li J, Shen R, Rohaim A, Mendoza Uriarte R, Fajer M, Perozo E, Roux B. Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel. The Journal of General Physiology. 153. PMID 34357375 DOI: 10.1085/jgp.202112875  0.769
2021 Zhao R, Dai H, Arias RJ, De Blas GA, Orta G, Pavarotti MA, Shen R, Perozo E, Mayorga LS, Darszon A, Goldstein SAN. Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils. Nature Communications. 12: 3855. PMID 34158477 DOI: 10.1038/s41467-021-24145-1  0.586
2021 Li J, Shen R, Reddy B, Perozo E, Roux B. Mechanism of C-type inactivation in the hERG potassium channel. Science Advances. 7. PMID 33514547 DOI: 10.1126/sciadv.abd6203  0.834
2020 Clark MD, Contreras GF, Shen R, Perozo E. Electromechanical coupling in the hyperpolarization-activated K channel KAT1. Nature. PMID 32461693 DOI: 10.1038/S41586-020-2335-4  0.87
2020 Li J, Shen R, Hoon Koh Y, Perozo E, Roux B. Molecular Determinants of C-type Inactivation for the hERG Channel and Its Disease-associated Mutants Biophysical Journal. 118: 111a. DOI: 10.1016/J.Bpj.2019.11.755  0.703
2020 Lu A, Park S, Reddy B, Fei J, Perozo E. Using Fluorescence Microscopy to Characterize the Role of Mechanosensation in Cell Division Biophysical Journal. 118: 529a. DOI: 10.1016/J.Bpj.2019.11.2906  0.647
2020 Reddy B, Bavi N, Perozo E. Influence of the Lipid-Protein Interface on MSCS Mechanosensitive Channel Gating at High Resolutions Biophysical Journal. 118: 523a. DOI: 10.1016/J.Bpj.2019.11.2876  0.841
2020 Erramilli SK, Li T, Nosol K, Tokarz P, Dutka P, Dominik PK, Perozo E, Kossiakoff AA. Visualizing Conformational Changes of the Magnesium Channel Cora using Synthetic Antibodies Biophysical Journal. 118: 273a. DOI: 10.1016/J.Bpj.2019.11.1570  0.54
2020 Shen R, Roux B, Perozo E. The Energy Landscape of Voltage Sensing in Ci-VSP Biophysical Journal. 118: 269a. DOI: 10.1016/J.Bpj.2019.11.1550  0.599
2020 Contreras GF, Clark MD, Shen R, Perozo E. A Molecular Mechanism for Gating Polarity in Non-Domain-Swapped Kv Channels Biophysical Journal. 118: 260a-261a. DOI: 10.1016/J.Bpj.2019.11.1511  0.843
2019 Reddy B, Bavi N, Lu A, Park Y, Perozo E. Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS. Elife. 8. PMID 31880537 DOI: 10.2210/Pdb6Pwo/Pdb  0.853
2019 Rangl M, Schmandt N, Perozo E, Scheuring S. Real time dynamics of gating-related conformational changes in CorA. Elife. 8. PMID 31774394 DOI: 10.7554/eLife.47322  0.517
2019 Reddy B, Bavi N, Lu A, Park Y, Perozo E. Author response: Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS Elife. DOI: 10.7554/Elife.50486.Sa2  0.836
2019 Rangl M, Schmandt N, Perozo E, Scheuring S. Author response: Real time dynamics of Gating-Related conformational changes in CorA Elife. DOI: 10.7554/Elife.47322.Sa2  0.322
2019 Roux B, Song K, Hoon Koh Y, Perozo E, Sosnick TR. Structural Dynamics of Potassium Channel Monomer in a Membrane Environment and Tetrameric Assembly Biophysical Journal. 116: 461a. DOI: 10.1016/J.Bpj.2018.11.2490  0.622
2019 Reddy B, Lu A, Bavi N, Hsu A, Borgnia M, Perozo E. High-Resolution Structures of MscS in a Lipid Bilayer: Reinterpreting “Force from Lipids” Activation in Mechanosensitive Channels Biophysical Journal. 116: 459a. DOI: 10.1016/J.Bpj.2018.11.2479  0.845
2019 Song KC, Koh Y, Perozo E, Roux B, Sosnick TR. Controlling the Folding and Misfolding of Potassium Channels Biophysical Journal. 116: 301a. DOI: 10.1016/J.Bpj.2018.11.1630  0.633
2019 Clark MD, Contreras G, Shen R, Perozo E. Structural Basis for Electromechanical Coupling in a Hyperpolarization-Activated Ion Channel Biophysical Journal. 116: 15a. DOI: 10.1016/J.Bpj.2018.11.123  0.852
2019 Li J, Hoon Koh Y, Rohaim A, Perozo E, Roux B. Atomic-Level Characterization of C-Type Inactivation for Voltage-Gated Potassium Channels Shaker and hERG Biophysical Journal. 116: 14a-15a. DOI: 10.1016/J.Bpj.2018.11.121  0.616
2018 Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, Goldstein SAN. Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor. Proceedings of the National Academy of Sciences of the United States of America. PMID 30478045 DOI: 10.1073/pnas.1816189115  0.44
2018 Li J, Ostmeyer J, Cuello LG, Perozo E, Roux B. Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel. The Journal of General Physiology. PMID 30072373 DOI: 10.1085/Jgp.201812082  0.809
2018 Lau C, Hunter MJ, Stewart A, Perozo E, Vandenberg JI. Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy. The Journal of Physiology. PMID 29377132 DOI: 10.1113/JP274888  0.519
2018 Li J, Jostmey J, Perozo E, Roux B. A Universal Molecular Mechanism for C-type Inactivation in Potassium Channels Biophysical Journal. 114: 474a-475a. DOI: 10.1016/J.Bpj.2017.11.2611  0.618
2017 Bavi N, Martinac AD, Cortes DM, Bavi O, Ridone P, Nomura T, Hill AP, Martinac B, Perozo E. Structural Dynamics of the MscL C-terminal Domain. Scientific Reports. 7: 17229. PMID 29222414 DOI: 10.1016/J.Bpj.2016.11.2569  0.756
2017 Cuello LG, Cortes DM, Perozo E. The gating cycle of a K(+) channel at atomic resolution. Elife. 6. PMID 29165243 DOI: 10.7554/Elife.28032  0.765
2017 Li J, Ostmeyer J, Boulanger E, Rui H, Perozo E, Roux B. Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973956 DOI: 10.1073/Pnas.1706983114  0.673
2017 Vandenberg JI, Perozo E, Allen TW. Towards a Structural View of Drug Binding to hERG K(+) Channels. Trends in Pharmacological Sciences. PMID 28711156 DOI: 10.1016/J.Tips.2017.06.004  0.497
2017 Kratochvil HT, Maj M, Matulef K, Annen AW, Ostmeyer J, Perozo E, Roux B, Valiyaveetil FI, Zanni MT. Probing the effects of gating on the ion occupancy of the K(+) channel selectivity filter using 2D IR spectroscopy. Journal of the American Chemical Society. PMID 28472884 DOI: 10.1021/Jacs.7B01594  0.673
2017 Cuello LG, Cortes DM, Perozo E. Author response: The gating cycle of a K+ channel at atomic resolution Elife. DOI: 10.7554/Elife.28032.016  0.719
2017 Li J, Ostmeyer J, Perozo E, Roux B. Molecular Determinants of Structural Coupling between C-Type Inactivation and Inner Gate Opening in K + Channels Biophysical Journal. 112: 544a. DOI: 10.1016/J.Bpj.2016.11.2941  0.652
2017 Schmandt N, Milewski M, Perozo E. Contribution of Individual Pore Residues to Mg 2+ Permeation and Divalent Cation Selectivity in Cora Biophysical Journal. 112: 502a. DOI: 10.1016/J.BPJ.2016.11.2715  0.345
2017 Zhao R, Kennedy K, Li Q, Perozo E, Goldstein SA. Identification of Activating and Inhibiting Gating Modifier Toxins that Target the S3-S4 Loop of the Human Proton Channel, hHv1 Biophysical Journal. 112: 415a. DOI: 10.1016/J.BPJ.2016.11.2223  0.705
2017 Kennedy K, Zhao R, Li Q, Perozo E, De Blas GA, Pavarotti MA, Arias R, Mayorga LS, Goldstein SA. A Designer Peptide Toxin Isolated by Phage Display that Inhibits the Human Voltage-Gated Proton Channel, hHv1 Biophysical Journal. 112: 415a. DOI: 10.1016/J.BPJ.2016.11.2222  0.693
2016 Kratochvil HT, Carr JK, Matulef K, Annen AW, Li H, Maj M, Ostmeyer J, Serrano AL, Raghuraman H, Moran SD, Skinner JL, Perozo E, Roux B, Valiyaveetil FI, Zanni MT. Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy. Science (New York, N.Y.). 353: 1040-1044. PMID 27701114 DOI: 10.1126/Science.Aag1447  0.795
2016 Bavi N, Cox CD, Perozo E, Martinac B. Towards a structural blueprint for bilayer-mediated channel mechanosensitivity. Channels (Austin, Tex.). 0. PMID 27533603 DOI: 10.1080/19336950.2016.1224624  0.803
2016 Bavi N, Cortes DM, Cox CD, Rohde PR, Liu W, Deitmer JW, Bavi O, Strop P, Hill AP, Rees D, Corry B, Perozo E, Martinac B. The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels. Nature Communications. 7: 11984. PMID 27329693 DOI: 10.1038/Ncomms11984  0.819
2016 Medovoy D, Perozo E, Roux B. Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel. Biochimica Et Biophysica Acta. PMID 26896693 DOI: 10.1016/J.Bbamem.2016.02.019  0.832
2016 Matthies D, Dalmas O, Borgnia MJ, Dominik PK, Merk A, Rao P, Reddy BG, Islam S, Bartesaghi A, Perozo E, Subramaniam S. Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating. Cell. 164: 747-56. PMID 26871634 DOI: 10.1016/J.Cell.2015.12.055  0.833
2016 Shen R, Li Q, Medovoy D, Meng Y, Roux B, Perozo E. Computational Characterization of Conformational Transitions in the Voltage-Sensing Domain of Ci-VSP Biophysical Journal. 110: 106a. DOI: 10.1016/J.Bpj.2015.11.629  0.839
2016 Reddy B, Dominik P, Dalmas O, Kossiakoff T, Perozo E. Locking the Asymmetric open Conformation of MG2+ Channel Cora with a Synthetic Antibody Fragment Biophysical Journal. 110: 605a. DOI: 10.1016/J.Bpj.2015.11.3232  0.848
2016 Rotella C, Kilpatrick JI, Capponi S, Holmgren M, Bezanilla F, Perozo E, Jarvis SP. High Resolution Imaging Atomic Force Microscope Study of Interactions at the Membrane-Fluid Interface Biophysical Journal. 110: 580a-581a. DOI: 10.1016/J.Bpj.2015.11.3103  0.74
2016 Matthies D, Dalmas O, Borgnia M, Dominik P, Merk A, Rao P, Reddy B, Islam S, Bartesaghi A, Perozo E, Subramaniam S. Structures of the Mg2+ Channel Cora in the Open State by Cryo Electron Microscopy Biophysical Journal. 110: 291a. DOI: 10.1016/J.Bpj.2015.11.1574  0.836
2016 Matthies D, Dalmas O, Borgnia MJ, Dominik PK, Merk A, Rao P, Reddy BG, Islam S, Bartesaghi A, Perozo E, Subramaniam S. Single-Particle Cryo-EM Studies of a 200-kDa Magnesium Ion Channel Reveal Large Structural Changes Upon Gating Biophysical Journal. 110: 10a. DOI: 10.1016/J.Bpj.2015.11.109  0.843
2015 Dominik PK, Borowska MT, Dalmas O, Kim SS, Perozo E, Keenan RJ, Kossiakoff AA. Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs. Structure (London, England : 1993). PMID 26749445 DOI: 10.1016/J.Str.2015.11.014  0.73
2015 Li Q, Shen R, Treger JS, Wanderling SS, Milewski W, Siwowska K, Bezanilla F, Perozo E. Resting state of the human proton channel dimer in a lipid bilayer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26443860 DOI: 10.1073/Pnas.1515043112  0.868
2015 van der Cruijsen EA, Koers EJ, Sauvée C, Hulse RE, Weingarth M, Ouari O, Perozo E, Tordo P, Baldus M. Biomolecular DNP-Supported NMR Spectroscopy using Site-Directed Spin Labeling. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 12971-7. PMID 26315337 DOI: 10.1002/Chem.201501376  0.765
2015 Raghuraman H, Perozo E. Dynamics of the KcsA Selectivity Filter Probed using Intrinsic Tyrosine Fluorescence Biophysical Journal. 108: 118a-119a. DOI: 10.1016/J.Bpj.2014.11.664  0.755
2015 Li Q, Skalska J, Wanderling S, Perozo E. Lipid-Dependent Conformational Transitions in KvAP are Driven by Voltage Sensing Domain Biophysical Journal. 108: 426a. DOI: 10.1016/J.BPJ.2014.11.2331  0.487
2014 McGreevy R, Singharoy A, Li Q, Zhang J, Xu D, Perozo E, Schulten K. xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures. Acta Crystallographica. Section D, Biological Crystallography. 70: 2344-55. PMID 25195748 DOI: 10.1107/S1399004714013856  0.317
2014 Dalmas O, Sompornpisut P, Bezanilla F, Perozo E. Molecular mechanism of Mg2+-dependent gating in CorA. Nature Communications. 5: 3590. PMID 24694723 DOI: 10.1038/Ncomms4590  0.808
2014 Hulse RE, Sachleben JR, Wen PC, Moradi M, Tajkhorshid E, Perozo E. Conformational dynamics at the inner gate of KcsA during activation. Biochemistry. 53: 2557-9. PMID 24621378 DOI: 10.1021/Bi500168U  0.829
2014 Dalmas O, Sandtner W, Medovoy D, Frezza L, Bezanilla F, Perozo E. A repulsion mechanism explains magnesium permeation and selectivity in CorA. Proceedings of the National Academy of Sciences of the United States of America. 111: 3002-7. PMID 24516146 DOI: 10.1073/Pnas.1319054111  0.813
2014 Randich AM, Cuello LG, Wanderling SS, Perozo E. Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP. Biochemistry. 53: 1627-36. PMID 24490868 DOI: 10.1021/Bi4014243  0.862
2014 Li Q, Wanderling S, Paduch M, Medovoy D, Singharoy A, McGreevy R, Villalba-Galea CA, Hulse RE, Roux B, Schulten K, Kossiakoff A, Perozo E. Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. Nature Structural & Molecular Biology. 21: 244-52. PMID 24487958 DOI: 10.1038/Nsmb.2768  0.827
2014 Raghuraman H, Islam SM, Mukherjee S, Roux B, Perozo E. Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating. Proceedings of the National Academy of Sciences of the United States of America. 111: 1831-6. PMID 24429344 DOI: 10.1073/Pnas.1314875111  0.841
2014 Li Q, Wanderling S, Sompornpisut P, Perozo E. Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain. Nature Structural & Molecular Biology. 21: 160-6. PMID 24413055 DOI: 10.1038/Nsmb.2747  0.753
2014 Raghuraman H, Islam SM, Mukherjee S, Roux B, Perozo E. Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 5 (1831-1836) DOI: 10.1073/pnas.1314875111) Proceedings of the National Academy of Sciences of the United States of America. 111: 4644. DOI: 10.1073/pnas.1402205111  0.551
2014 Li Q, Wanderling S, Perozo E. The Resting State of Human Proton Channel from Functional and Structural Determinations Biophysical Journal. 106: 745a. DOI: 10.1016/J.BPJ.2013.11.4103  0.529
2014 Hulse RE, Sachleben JR, Perozo E. Ion-Selectivity Filter Interactions in KCSA from 1D 87Rb+ NMR Biophysical Journal. 106: 540a. DOI: 10.1016/J.Bpj.2013.11.3010  0.802
2014 Randich AM, Vargas E, Wanderling SS, Perozo E. Structural Basis of Lipid-Driven Conformational Changes in the Hyperpolarization-Activated Potassium Channel MVP Biophysical Journal. 106: 437a. DOI: 10.1016/J.Bpj.2013.11.2463  0.866
2014 Perozo E, Li Q, Wanderlin S. Structural Basis of Voltage-Dependent Gating in Ci-VSP Biophysical Journal. 106: 241a. DOI: 10.1016/J.BPJ.2013.11.1412  0.473
2014 Cuello LG, Cortes DM, Perozo E. A Structural Driven Kinetic Cycle for KcsA Gating Biophysical Journal. 106: 16a. DOI: 10.1016/J.Bpj.2013.11.140  0.717
2013 Ostmeyer J, Chakrapani S, Pan AC, Perozo E, Roux B. Recovery from slow inactivation in K+ channels is controlled by water molecules. Nature. 501: 121-4. PMID 23892782 DOI: 10.1038/Nature12395  0.774
2013 van der Cruijsen EA, Nand D, Weingarth M, Prokofyev A, Hornig S, Cukkemane AA, Bonvin AM, Becker S, Hulse RE, Perozo E, Pongs O, Baldus M. Importance of lipid-pore loop interface for potassium channel structure and function. Proceedings of the National Academy of Sciences of the United States of America. 110: 13008-13. PMID 23882077 DOI: 10.1073/Pnas.1305563110  0.859
2013 White EA, Raghuraman H, Perozo E, Glotzer M. Binding of the CYK-4 subunit of the centralspindlin complex induces a large scale conformational change in the kinesin subunit. The Journal of Biological Chemistry. 288: 19785-95. PMID 23720745 DOI: 10.1074/Jbc.M113.463695  0.697
2013 Hulse RE, Henzler-Wildman K, Perozo E. Dynamics of Conformational Transitions during KcsA Gating from EPR and Solution NMR Experiments Biophysical Journal. 104: 128a. DOI: 10.1016/J.Bpj.2012.11.734  0.801
2013 Medovoy D, Li Q, Perozo E, Roux B. The Energetic Landscape of the Putative Voltage-Driven Conformational Transition in Ci-VSP Biophysical Journal. 104: 124a. DOI: 10.1016/J.Bpj.2012.11.714  0.811
2013 Bourdeau RW, Perozo E. Reversible Gating of the NaK Channel by Changes in Redox Potential Biophysical Journal. 104: 542a. DOI: 10.1016/J.Bpj.2012.11.3005  0.844
2013 Randich AM, Wanderling S, Perozo E. Structural Analysis of S4-S5 Linker Architecture in Depolarization and Hyperpolarization activated K+ Channels Biophysical Journal. 104: 467a. DOI: 10.1016/J.Bpj.2012.11.2580  0.852
2013 Ostmeyer JL, Chakrapani S, Perozo E, Roux B. Rate of Recovery from Slow Inactivation in K+ Channels Controlled by Buried Water Molecules Biophysical Journal. 104: 25a-26a. DOI: 10.1016/J.Bpj.2012.11.174  0.755
2013 Wen P, Moradi M, Hulse RE, Perozo E, Tajkhorshid E. Conformational Transition of KcsA Gating and the Mechanism of its pH-Dependence Biophysical Journal. 104: 25a. DOI: 10.1016/J.Bpj.2012.11.173  0.856
2012 Vargas E, Yarov-Yarovoy V, Khalili-Araghi F, Catterall WA, Klein ML, Tarek M, Lindahl E, Schulten K, Perozo E, Bezanilla F, Roux B. An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations. The Journal of General Physiology. 140: 587-94. PMID 23183694 DOI: 10.1085/Jgp.201210873  0.738
2012 Li Q, Jogini V, Wanderling S, Cortes DM, Perozo E. Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP. Biochemistry. 51: 8132-42. PMID 22989304 DOI: 10.1021/Bi300980Q  0.772
2012 Dalmas O, Hyde HC, Hulse RE, Perozo E. Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate. Journal of the American Chemical Society. 134: 16360-9. PMID 22946877 DOI: 10.1021/Ja3069038  0.829
2012 Raghuraman H, Cordero-Morales JF, Jogini V, Pan AC, Kollewe A, Roux B, Perozo E. Mechanism of Cd2+ coordination during slow inactivation in potassium channels. Structure (London, England : 1993). 20: 1332-42. PMID 22771214 DOI: 10.1016/J.Str.2012.03.027  0.842
2012 Raghuraman H, Li Q, Wanderling S, Villalba-Galea CA, Perozo E. Structural Dynamics in the Resting and Activated States of the Voltage Sensor of Ci-VSP from Dipolar Distance Measurements Biophysical Journal. 102: 685a. DOI: 10.1016/J.Bpj.2011.11.3724  0.734
2012 Medovoy D, Cuello LCG, Perozo E, Roux B. A Three-Ion Selectivity Filter Potential Energy Landscape of a Putative Open-Conductive KcsA Biophysical Journal. 102: 676a-677a. DOI: 10.1016/J.Bpj.2011.11.3680  0.841
2012 Randich AM, Perozo E. A Random Mutagenesis Approach to Probing Electromechanical Coupling in the Hyperpolarization-Activated Channel MVP Biophysical Journal. 102: 529a. DOI: 10.1016/J.Bpj.2011.11.2892  0.854
2012 Cuello LG, Cortes DM, Perozo E. Role of Structural Water in the Stabilization of the KcsA C-Type Inactivated Selectivity Filter: Evidence from High-Resolution Structures Biophysical Journal. 102: 529a. DOI: 10.1016/J.Bpj.2011.11.2891  0.743
2012 Li Q, Wanderling S, Villalba-Galea CA, Perozo E. The Resting and Activated Conformations of the Voltage Sensor of Ci-VSP from Functional and Solvent Accessibility Determinations Biophysical Journal. 102: 36a. DOI: 10.1016/J.BPJ.2011.11.224  0.469
2012 Dalmas O, Hyde HC, Perozo E. Distance Determination in Multimeric Membrane Protein by Symmetry Constrained Analysis of Double Electron-Electron Resonance Spectroscopy Biophysical Journal. 102: 405a. DOI: 10.1016/J.Bpj.2011.11.2212  0.822
2012 Sompornpisut P, Dalmas O, Perozo E. The Open Conformation of the Mg2+ Channel CorA from Solvent Accessibility and Distance Constraints Biophysical Journal. 102: 338a. DOI: 10.1016/J.Bpj.2011.11.1853  0.842
2011 Torbeev VY, Raghuraman H, Hamelberg D, Tonelli M, Westler WM, Perozo E, Kent SB. Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proceedings of the National Academy of Sciences of the United States of America. 108: 20982-7. PMID 22158985 DOI: 10.1073/Pnas.1111202108  0.685
2011 Pan AC, Cuello LG, Perozo E, Roux B. Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations. The Journal of General Physiology. 138: 571-80. PMID 22124115 DOI: 10.1085/Jgp.201110670  0.816
2011 Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M. Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway. The Journal of Biological Chemistry. 286: 39091-9. PMID 21908602 DOI: 10.1074/Jbc.M111.292060  0.861
2011 Uysal S, Cuello LG, Cortes DM, Koide S, Kossiakoff AA, Perozo E. Mechanism of activation gating in the full-length KcsA K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 108: 11896-9. PMID 21730186 DOI: 10.1073/Pnas.1105112108  0.786
2011 Cordero-Morales JF, Jogini V, Chakrapani S, Perozo E. A multipoint hydrogen-bond network underlying KcsA C-type inactivation. Biophysical Journal. 100: 2387-93. PMID 21575572 DOI: 10.1016/J.Bpj.2011.01.073  0.849
2011 Chakrapani S, Cordero-Morales JF, Jogini V, Pan AC, Cortes DM, Roux B, Perozo E. On the structural basis of modal gating behavior in K(+) channels. Nature Structural & Molecular Biology. 18: 67-74. PMID 21186363 DOI: 10.1038/Nsmb.1968  0.86
2011 Cordero-Morales JF, Jogini V, Vasquez V, Bourdeau RW, Yu H, Roux B, Tristani-Firouzi M, Perozo E. Engineering the hERG1 Selectivity Filter into the NaK Pore Domain Biophysical Journal. 100: 584a. DOI: 10.1016/J.Bpj.2010.12.3372  0.827
2011 Bourdeau RW, Vasquez V, Cordero-Morales JF, Perozo E. A Functional Analysis of NaK at the Single Channel Level Biophysical Journal. 100: 583a-584a. DOI: 10.1016/J.Bpj.2010.12.3371  0.862
2011 Cordero-Morales JF, Jogini V, Lewis A, Vasquez V, Medovoy D, Tristani-Firouzi M, Perozo E. Structural Basis of an Inherited hERG1 Long QT Mutant Biophysical Journal. 100: 426a. DOI: 10.1016/J.Bpj.2010.12.2517  0.825
2011 Dalmas O, Perozo E. Structural Rearrangements Underlying Mg2+ Dependent Gating in Cora Biophysical Journal. 100: 272a. DOI: 10.1016/J.Bpj.2010.12.1696  0.778
2010 Hulse RE, Li Q, Perozo E. Up a hydrophobic creek with a short paddle. Cell. 142: 515-6. PMID 20723752 DOI: 10.1016/J.Cell.2010.08.005  0.816
2010 Dalmas O, Cuello LG, Jogini V, Cortes DM, Roux B, Perozo E. Structural dynamics of the magnesium-bound conformation of CorA in a lipid bilayer. Structure (London, England : 1993). 18: 868-78. PMID 20637423 DOI: 10.1016/J.Str.2010.04.009  0.816
2010 Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DG, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B, Perozo E. Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 466: 272-5. PMID 20613845 DOI: 10.1038/Nature09136  0.865
2010 Cuello LG, Jogini V, Cortes DM, Perozo E. Structural mechanism of C-type inactivation in K(+) channels. Nature. 466: 203-8. PMID 20613835 DOI: 10.1038/Nature09153  0.87
2010 Chakrapani S, Sompornpisut P, Intharathep P, Roux B, Perozo E. The activated state of a sodium channel voltage sensor in a membrane environment. Proceedings of the National Academy of Sciences of the United States of America. 107: 5435-40. PMID 20207950 DOI: 10.1073/Pnas.0914109107  0.861
2010 Cuello LG, Jogini V, Cortes DM, Sompornpisut A, Purdy MD, Wiener MC, Perozo E. Design and characterization of a constitutively open KcsA. Febs Letters. 584: 1133-8. PMID 20153331 DOI: 10.1016/J.Febslet.2010.02.015  0.829
2010 Cuello LG, Cortes DM, Jogini V, Sompornpisut A, Perozo E. A molecular mechanism for proton-dependent gating in KcsA. Febs Letters. 584: 1126-32. PMID 20138880 DOI: 10.1016/J.Febslet.2010.02.003  0.815
2010 Dalmas O, Sandtner W, Santos JS, Frezza L, Cuello LG, Bezanilla F, Perozo E. Analysis of CorA-Catalyzed Mg2+ Selective Currents in Xenopus Oocytes Biophysical Journal. 98: 705a. DOI: 10.1016/J.Bpj.2009.12.3869  0.808
2010 Pan AC, Chakrapani S, Jogini V, Cuello LG, Cortes DM, Perozo E, Roux B. The Importance of Ion Binding for Potassium Channel Inactivation and Recovery Biophysical Journal. 98: 621a. DOI: 10.1016/J.Bpj.2009.12.3400  0.859
2010 Chakrapani S, Jogini V, Perozo E. Effect of Altered Ion Occupancy on Permeation and Inactivation Gating in K+ Channel Biophysical Journal. 98: 520a. DOI: 10.1016/J.BPJ.2009.12.2828  0.853
2010 Cuello LG, Cortes DM, Perozo E. An Engineered Cysteine-Bridge Locks KcsA Inner Bundle Gate in Its Open Conformation Biophysical Journal. 98: 314a. DOI: 10.1016/J.Bpj.2009.12.1706  0.794
2010 Raghuraman H, Perozo E. Gating-Related Conformational Changes in the Outer Vestibule of KcsA: a Fluorescence and Pulsed-Epr Analysis Biophysical Journal. 98: 314a. DOI: 10.1016/J.Bpj.2009.12.1705  0.804
2010 Cuello LG, Cortes DM, Perozo E. High-Resolution Crystallographic Analysis of the Kcsa Gating Cycle from Cysteine-Trapped Open Channels Biophysical Journal. 98: 314a. DOI: 10.1016/J.Bpj.2009.12.1704  0.787
2009 Takacs Z, Toups M, Kollewe A, Johnson E, Cuello LG, Driessens G, Biancalana M, Koide A, Ponte CG, Perozo E, Gajewski TF, Suarez-Kurtz G, Koide S, Goldstein SA. A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library. Proceedings of the National Academy of Sciences of the United States of America. 106: 22211-6. PMID 20007782 DOI: 10.1073/Pnas.0910123106  0.808
2009 Vásquez V, Perozo E. Structural biology: A channel with a twist. Nature. 461: 47-9. PMID 19727188 DOI: 10.1038/461047A  0.795
2009 Uysal S, Vásquez V, Tereshko V, Esaki K, Fellouse FA, Sidhu SS, Koide S, Perozo E, Kossiakoff A. Crystal structure of full-length KcsA in its closed conformation. Proceedings of the National Academy of Sciences of the United States of America. 106: 6644-9. PMID 19346472 DOI: 10.1073/Pnas.0810663106  0.783
2009 Torbeev VY, Raghuraman H, Mandal K, Senapati S, Perozo E, Kent SB. Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy. Journal of the American Chemical Society. 131: 884-5. PMID 19117390 DOI: 10.1021/Ja806526Z  0.668
2009 Goetz BA, Perozo E, Locher KP. Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking. Febs Letters. 583: 266-70. PMID 19101549 DOI: 10.1016/J.Febslet.2008.12.020  0.372
2009 Cordero-Morales JF, Jogini V, Lewis A, Vasquez V, Tristani-Firouzi M, Perozo E. On the Nature of hERG Inactivation using KcsA, Shaker and Kv1.2 as Structural and Functional Models Biophysical Journal. 96: 188a-189a. DOI: 10.1016/J.Bpj.2008.12.885  0.875
2009 Chakrapani S, Jogini V, Cuello LG, Cortes M, Perozo E. On the Structure-Function correlates of Ion Occupancy and modulation of C-type Inactivation Biophysical Journal. 96: 657a. DOI: 10.1016/J.Bpj.2008.12.3471  0.868
2009 Cuello LG, Chakrapani S, Cortes DM, Dalmas O, Perozo E. Influence Of The Kcsa C-terminal Domain In The Coupling Between Activation And Inactivation Gates Biophysical Journal. 96: 657a. DOI: 10.1016/J.Bpj.2008.12.3470  0.867
2009 Pan AC, Jogini V, Cuello LG, Cortes D, Perozo E, Roux B. Free Energy Landscape for the Inactivation of the KcsA Potassium Channel Biophysical Journal. 96: 657a. DOI: 10.1016/J.Bpj.2008.12.3469  0.862
2009 Raghuraman H, Cordero-Morales JF, Jogini V, Perozo E. Gating-related Structural Dynamics in the Outer Vestibule of KcsA: A Functional and Spectroscopic Analysis Biophysical Journal. 96: 394a. DOI: 10.1016/J.Bpj.2008.12.2932  0.834
2009 Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DG, Cordero-Morales JF, Chakrapani S, Roux B, Perozo E. Structural Basis For The Coupling Between Activation And Inactivation Gating In Potassium Channels Biophysical Journal. 96: 381a. DOI: 10.1016/J.Bpj.2008.12.2852  0.872
2009 Uysal S, Cuello LG, Jogini V, Cortes DM, Koide S, Perozo E, Kossiakoff A. Crystal Structure Of Full-length Kcsa Trapped In Open Conformation Reveals That C-terminal Domain Fine Tunes Activation And Coupled Inactivation Biophysical Journal. 96: 370a. DOI: 10.1016/J.Bpj.2008.12.1994  0.835
2008 Vásquez V, Sotomayor M, Cordero-Morales J, Schulten K, Perozo E. A structural mechanism for MscS gating in lipid bilayers. Science (New York, N.Y.). 321: 1210-4. PMID 18755978 DOI: 10.1126/Science.1159674  0.858
2008 Sompornpisut P, Roux B, Perozo E. Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data. Biophysical Journal. 95: 5349-61. PMID 18676641 DOI: 10.1529/Biophysj.108.142984  0.74
2008 Vásquez V, Sotomayor M, Cortes DM, Roux B, Schulten K, Perozo E. Three-dimensional architecture of membrane-embedded MscS in the closed conformation. Journal of Molecular Biology. 378: 55-70. PMID 18343404 DOI: 10.1016/J.Jmb.2007.10.086  0.785
2008 Chakrapani S, Cuello LG, Cortes DM, Perozo E. Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer. Structure (London, England : 1993). 16: 398-409. PMID 18334215 DOI: 10.1016/J.Str.2007.12.015  0.811
2007 Chakrapani S, Cordero-Morales JF, Perozo E. A quantitative description of KcsA gating II: single-channel currents. The Journal of General Physiology. 130: 479-96. PMID 17938231 DOI: 10.1085/Jgp.200709844  0.831
2007 Chakrapani S, Cordero-Morales JF, Perozo E. A quantitative description of KcsA gating I: macroscopic currents. The Journal of General Physiology. 130: 465-78. PMID 17938230 DOI: 10.1085/Jgp.200709843  0.845
2007 Cordero-Morales JF, Jogini V, Lewis A, Vásquez V, Cortes DM, Roux B, Perozo E. Molecular driving forces determining potassium channel slow inactivation. Nature Structural & Molecular Biology. 14: 1062-9. PMID 17922012 DOI: 10.1038/Nsmb1309  0.865
2007 Hvorup RN, Goetz BA, Niederer M, Hollenstein K, Perozo E, Locher KP. Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF. Science (New York, N.Y.). 317: 1387-90. PMID 17673622 DOI: 10.1126/Science.1145950  0.337
2007 Vásquez V, Cortes DM, Furukawa H, Perozo E. An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis. Biochemistry. 46: 6766-73. PMID 17500538 DOI: 10.1021/Bi700322K  0.782
2007 Chakrapani S, Perozo E. How to gate an ion channel: lessons from MthK. Nature Structural & Molecular Biology. 14: 180-2. PMID 17334406 DOI: 10.1038/nsmb0307-180  0.74
2007 Sotomayor M, Vásquez V, Perozo E, Schulten K. Ion conduction through MscS as determined by electrophysiology and simulation. Biophysical Journal. 92: 886-902. PMID 17114233 DOI: 10.1529/Biophysj.106.095232  0.781
2007 Perozo E, Cortes D, Vasquez V, Wu J, Pornthep S, Martinac B. 3.2. Lipid–protein interactions and the gating of prokaryotic mechanosensitive channels Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 148: S13-S14. DOI: 10.1016/J.Cbpa.2007.06.035  0.783
2006 Blunck R, Cordero-Morales JF, Cuello LG, Perozo E, Bezanilla F. Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. The Journal of General Physiology. 128: 569-81. PMID 17043150 DOI: 10.1085/Jgp.200609638  0.861
2006 Cordero-Morales JF, Cuello LG, Zhao Y, Jogini V, Cortes DM, Roux B, Perozo E. Molecular determinants of gating at the potassium-channel selectivity filter. Nature Structural & Molecular Biology. 13: 311-8. PMID 16532009 DOI: 10.1038/Nsmb1069  0.869
2006 Cordero-Morales JF, Cuello LG, Perozo E. Voltage-dependent gating at the KcsA selectivity filter. Nature Structural & Molecular Biology. 13: 319-22. PMID 16532008 DOI: 10.1038/Nsmb1070  0.842
2006 Perozo E. Gating prokaryotic mechanosensitive channels. Nature Reviews. Molecular Cell Biology. 7: 109-19. PMID 16493417 DOI: 10.1038/nrm1833  0.459
2006 Zhao Y, Jogini V, Perozo E, Roux B. S3h1-1 Molecular Determinants of Gating at the K^+ Channel Selectivity Filter, Probed by Protein Crystallography and Molecular Dynamics Simulations(S3-h1: "Structural Aspects of Channel and Transporter Proteins",Symposia,Abstract,Meeting Program of EABS & BSJ 2006) Seibutsu Butsuri. 46: S139. DOI: 10.2142/Biophys.46.S139_3  0.64
2005 Sale K, Song L, Liu YS, Perozo E, Fajer P. Explicit treatment of spin labels in modeling of distance constraints from dipolar EPR and DEER. Journal of the American Chemical Society. 127: 9334-5. PMID 15984837 DOI: 10.1021/Ja051652W  0.709
2005 Ptak CP, Cuello LG, Perozo E. Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces. Biochemistry. 44: 62-71. PMID 15628846 DOI: 10.1021/Bi048390F  0.82
2004 Cuello LG, Cortes DM, Perozo E. Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer. Science (New York, N.Y.). 306: 491-5. PMID 15486302 DOI: 10.1126/Science.1101373  0.764
2003 Perozo E, Rees DC. Structure and mechanism in prokaryotic mechanosensitive channels. Current Opinion in Structural Biology. 13: 432-42. PMID 12948773 DOI: 10.1016/S0959-440X(03)00106-4  0.575
2003 Bezanilla F, Perozo E. The voltage sensor and the gate in ion channels. Advances in Protein Chemistry. 63: 211-41. PMID 12629972 DOI: 10.1016/S0065-3233(03)63009-3  0.696
2002 Bezanilla F, Perozo E. Structural biology. Force and voltage sensors in one structure. Science (New York, N.Y.). 298: 1562-3. PMID 12446894 DOI: 10.1126/Science.1079369  0.655
2002 Perozo E, Cortes DM, Sompornpisut P, Kloda A, Martinac B. Open channel structure of MscL and the gating mechanism of mechanosensitive channels. Nature. 418: 942-8. PMID 12198539 DOI: 10.1038/Nature00992  0.772
2002 Li J, Xu Q, Cortes DM, Perozo E, Laskey A, Karlin A. Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides. Proceedings of the National Academy of Sciences of the United States of America. 99: 11605-10. PMID 12189213 DOI: 10.1073/Pnas.192439299  0.384
2002 Perozo E. New structural perspectives on K(+) channel gating. Structure (London, England : 1993). 10: 1027-9. PMID 12176380 DOI: 10.1016/S0969-2126(02)00812-2  0.563
2002 Perozo E, Kloda A, Cortes DM, Martinac B. Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating. Nature Structural Biology. 9: 696-703. PMID 12172537 DOI: 10.1038/Nsb827  0.557
2002 Perozo E, Cuello LG, Cortes DM, Liu YS, Sompornpisut P. EPR approaches to ion channel structure and function. Novartis Foundation Symposium. 245: 146-58; discussion 1. PMID 12027005 DOI: 10.1002/0470868759.Ch10  0.841
2001 Sompornpisut P, Liu YS, Perozo E. Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations. Biophysical Journal. 81: 2530-46. PMID 11606268 DOI: 10.1016/S0006-3495(01)75898-5  0.826
2001 Liu YS, Sompornpisut P, Perozo E. Structure of the KcsA channel intracellular gate in the open state. Nature Structural Biology. 8: 883-7. PMID 11573095 DOI: 10.1038/Nsb1001-883  0.873
2001 Perozo E, Kloda A, Cortes DM, Martinac B. Site-directed spin-labeling analysis of reconstituted Mscl in the closed state. The Journal of General Physiology. 118: 193-206. PMID 11479346 DOI: 10.1085/jgp.118.2.193  0.376
2001 Cortes DM, Cuello LG, Perozo E. Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. The Journal of General Physiology. 117: 165-80. PMID 11158168 DOI: 10.1085/Jgp.117.2.165  0.735
2000 Perozo E. Structure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis. The Journal of General Physiology. 115: 29-32. PMID 10613916 DOI: 10.1085/jgp.115.1.29  0.579
2000 Perozo E, Liu Y, Cortes DM, Cuello LG. Structural Basis of Activation Gating in K+ Channels Biochemical Society Transactions. 28: A135-A135. DOI: 10.1042/BST028A135B  0.742
1999 Perozo E, Cortes DM, Cuello LG. Structural rearrangements underlying K+-channel activation gating. Science (New York, N.Y.). 285: 73-8. PMID 10390363 DOI: 10.1126/Science.285.5424.73  0.759
1998 Perozo E. Shedding light on voltage-dependent gating. The Journal of General Physiology. 112: 373-6. PMID 9758857 DOI: 10.1085/jgp.112.4.373  0.508
1998 Perozo E, Cortes DM, Cuello LG. Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nature Structural Biology. 5: 459-69. PMID 9628484 DOI: 10.1038/Nsb0698-459  0.783
1998 Cuello LG, Romero JG, Cortes DM, Perozo E. pH-dependent gating in the Streptomyces lividans K+ channel. Biochemistry. 37: 3229-36. PMID 9536962 DOI: 10.1021/Bi972997X  0.853
1998 Tatulian SA, Cortes DM, Perozo E. Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy. Febs Letters. 423: 205-12. PMID 9512358 DOI: 10.1016/S0014-5793(98)00091-X  0.524
1997 Cortes DM, Perozo E. Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability. Biochemistry. 36: 10343-52. PMID 9254634 DOI: 10.1021/bi971018y  0.447
1994 Santacruz-Toloza L, Perozo E, Papazian DM. Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system. Biochemistry. 33: 1295-9. PMID 8312246 DOI: 10.1021/Bi00172A002  0.554
1994 Perozo E, Santacruz-Toloza L, Stefani E, Bezanilla F, Papazian DM. S4 mutations alter gating currents of Shaker K channels. Biophysical Journal. 66: 345-54. PMID 8161688 DOI: 10.1016/S0006-3495(94)80783-0  0.68
1994 Stefani E, Toro L, Perozo E, Bezanilla F. Gating of Shaker K+ channels: I. Ionic and gating currents. Biophysical Journal. 66: 996-1010. PMID 8038403 DOI: 10.1016/S0006-3495(94)80881-1  0.645
1994 Bezanilla F, Perozo E, Stefani E. Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophysical Journal. 66: 1011-21. PMID 8038375 DOI: 10.1016/S0006-3495(94)80882-3  0.666
1994 Bogomolni RA, Stoeckenius W, Szundi I, Perozo E, Olson KD, Spudich JL. Removal of transducer HtrI allows electrogenic proton translocation by sensory rhodopsin I. Proceedings of the National Academy of Sciences of the United States of America. 91: 10188-92. PMID 7937859 DOI: 10.1073/Pnas.91.21.10188  0.311
1994 Caputo C, Perozo E, Bezanilla F. Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS). Pflã¼Gers Archiv : European Journal of Physiology. 428: 315-22. PMID 7816554 DOI: 10.1007/Bf00724513  0.634
1993 Perozo E, Hubbell WL. Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source. Biochemistry. 32: 10471-8. PMID 8399193 DOI: 10.1021/Bi00090A025  0.62
1993 Perozo E, MacKinnon R, Bezanilla F, Stefani E. Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels. Neuron. 11: 353-8. PMID 8352943 DOI: 10.1016/0896-6273(93)90190-3  0.725
1992 Perozo E, Papazian DM, Stefani E, Bezanilla F. Gating currents in Shaker K+ channels. Implications for activation and inactivation models. Biophysical Journal. 62: 160-8; discussion 16. PMID 1600094 DOI: 10.1016/S0006-3495(92)81802-7  0.692
1991 Bezanilla F, Perozo E, Papazian DM, Stefani E. Molecular basis of gating charge immobilization in Shaker potassium channels. Science (New York, N.Y.). 254: 679-83. PMID 1948047 DOI: 10.1126/Science.1948047  0.692
1991 Perozo E, Jong DS, Bezanilla F. Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions. The Journal of General Physiology. 98: 19-34. PMID 1940848 DOI: 10.1085/Jgp.98.1.19  0.646
1991 Perozo E, Vandenberg CA, Jong DS, Bezanilla F. Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions. The Journal of General Physiology. 98: 1-17. PMID 1940846 DOI: 10.1085/Jgp.98.1.1  0.692
1991 Perozo E, Bezanilla F. Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis. Journal of Bioenergetics and Biomembranes. 23: 599-613. PMID 1917910 DOI: 10.1007/Bf00785813  0.682
1990 Perozo E, Bezanilla F. Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions. Neuron. 5: 685-90. PMID 2223093 DOI: 10.1016/0896-6273(90)90222-2  0.665
1989 Perozo E, Bezanilla F, Dipolo R. Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation. The Journal of General Physiology. 93: 1195-218. PMID 2769224 DOI: 10.1085/Jgp.93.6.1195  0.737
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