Narayanaswamy Srinivasan - Publications

Affiliations: 
Indian Institute of Science, Bengaluru, Karnataka, India 
Area:
Computational biology, Structural biology

231 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Prabantu VM, Gadiyaram V, Vishveshwara S, Srinivasan N. Comparison of structural networks across homologous proteins. Proteins. PMID 38058245 DOI: 10.1002/prot.26650  0.372
2023 Parvathy J, Yazhini A, Srinivasan N, Sowdhamini R. Interfacial residues in protein-protein complexes are in the eyes of the beholder. Proteins. PMID 37982321 DOI: 10.1002/prot.26628  0.363
2023 Prabantu VM, Tandon H, Sandhya S, Sowdhamini R, Srinivasan N. The alteration of structural network upon transient association between proteins studied using graph theory. Proteins. PMID 37902388 DOI: 10.1002/prot.26606  0.355
2023 Sidhanta SPD, Sowdhamini R, Srinivasan N. Comparative analysis of permanent and transient domain-domain interactions in multi-domain proteins. Proteins. PMID 37828826 DOI: 10.1002/prot.26581  0.309
2022 Naveenkumar N, Prabantu VM, Vishwanath S, Sowdhamini R, Srinivasan N. Structures of distantly-related interacting protein homologues are less divergent than non-interacting homologues. Febs Open Bio. PMID 36148593 DOI: 10.1002/2211-5463.13492  0.381
2022 Prabantu VM, Gadiyaram V, Vishveshwara S, Srinivasan N. Understanding structural variability in proteins using protein structural networks. Current Research in Structural Biology. 4: 134-145. PMID 35586857 DOI: 10.1016/j.crstbi.2022.04.002  0.362
2022 Kumar G, Srinivasan N, Sandhya S. Profiles of Natural and Designed Protein-Like Sequences Effectively Bridge Protein Sequence Gaps: Implications in Distant Homology Detection. Methods in Molecular Biology (Clifton, N.J.). 2449: 149-167. PMID 35507261 DOI: 10.1007/978-1-0716-2095-3_5  0.357
2022 Kalmankar NV, Pavalam M, Indrakumar S, Srinivasan N, Sowdhamini R. DSDBASE 2.0: updated version of DiSulphide dataBASE, a database on disulphide bonds in proteins. Database : the Journal of Biological Databases and Curation. 2022. PMID 35230424 DOI: 10.1093/database/baac005  0.31
2021 Yazhini A, Srinivasan N, Sandhya S. Sequence Divergence and Functional Specializations of the Ancient Spliceosomal SF3b: Implications in Flexibility and Adaptations of the Multi-Protein Complex. Frontiers in Genetics. 12: 747344. PMID 35082828 DOI: 10.3389/fgene.2021.747344  0.371
2021 Yazhini A, Sandhya S, Srinivasan N. Rewards of divergence in sequences, 3-D structures and dynamics of yeast and human spliceosome SF3b complexes. Current Research in Structural Biology. 3: 133-145. PMID 35028595 DOI: 10.1016/j.crstbi.2021.05.003  0.347
2021 Paul A, Subhadarshini S, Srinivasan N. Pseudokinases repurpose flexibility signatures associated with the protein kinase fold for non-catalytic roles. Proteins. PMID 34708889 DOI: 10.1002/prot.26271  0.308
2021 Yazhini A, Sidhanta DSP, Srinivasan N. D614G substitution at the hinge region enhances the stability of trimeric SARS-CoV-2 spike protein. Bioinformation. 17: 439-445. PMID 34092964 DOI: 10.6026/97320630017439  0.306
2021 Yazhini A, Srinivasan N, Sandhya S. Signatures of conserved and unique molecular features in Afrotheria. Scientific Reports. 11: 1011. PMID 33441654 DOI: 10.1038/s41598-020-79559-6  0.375
2020 Prabantu VM, Naveenkumar N, Srinivasan N. Influence of Disease-Causing Mutations on Protein Structural Networks. Frontiers in Molecular Biosciences. 7: 620554. PMID 33778000 DOI: 10.3389/fmolb.2020.620554  0.315
2020 Tandon H, de Brevern AG, Srinivasan N. Transient association between proteins elicits alteration of dynamics at sites far away from interfaces. Structure (London, England : 1993). PMID 33306961 DOI: 10.1016/j.str.2020.11.015  0.354
2020 Tandon H, Melarkode Vattekatte A, Srinivasan N, Sandhya S. Molecular and Structural Basis of Cross-Reactivity in Toxin-Antitoxin Systems. Toxins. 12. PMID 32751054 DOI: 10.3390/Toxins12080481  0.353
2020 Kumar G, Srinivasan N, Sandhya S. Artificial protein sequences enable recognition of vicinal and distant protein functional relationships. Proteins. PMID 32725917 DOI: 10.1002/Prot.25986  0.481
2020 Paul A, Srinivasan N. Genome-wide and structural analyses of pseudokinases encoded in the genome of Arabidopsis thaliana provide functional insights. Proteins. PMID 32667690 DOI: 10.1002/Prot.25981  0.491
2020 Maitra A, Sarkar MC, Raheja H, Biswas NK, Chakraborti S, Singh AK, Ghosh S, Sarkar S, Patra S, Mondal RK, Ghosh T, Chatterjee A, Banu H, Majumdar A, Chinnaswamy S, ... Srinivasan N, et al. Mutations in SARS-CoV-2 viral RNA identified in Eastern India: Possible implications for the ongoing outbreak in India and impact on viral structure and host susceptibility. Journal of Biosciences. 45. PMID 32515358 DOI: 10.1007/S12038-020-00046-1  0.374
2020 Melarkode Vattekatte A, Narwani TJ, Floch A, Maljković M, Bisoo S, Shinada NK, Kranjc A, Gelly JC, Srinivasan N, Mitić N, de Brevern AG. Data set of intrinsically disordered proteins analysed at a local protein conformation level. Data in Brief. 29: 105383. PMID 32195305 DOI: 10.1016/J.Dib.2020.105383  0.422
2020 Yazhini A, Srinivasan N. How good are comparative models in the understanding of protein dynamics? Proteins. PMID 31999374 DOI: 10.1002/Prot.25879  0.397
2020 Melarkode Vattekatte A, Jairaj Narwani T, Floch A, Maljkovic M, Bisoo S, Shinada NK, Kranjc A, Gelly JC, Srinivasan N, Mitic N, de Brevern AG. A structural entropy index to analyse local conformations in Intrinsically Disordered Proteins. Journal of Structural Biology. 107464. PMID 31978465 DOI: 10.1016/J.Jsb.2020.107464  0.376
2019 Faure G, Joseph AP, Craveur P, Narwani TJ, Srinivasan N, Gelly JC, Rebehmed J, de Brevern AG. iPBAvizu: a PyMOL plugin for an efficient 3D protein structure superimposition approach. Source Code For Biology and Medicine. 14: 5. PMID 31700529 DOI: 10.1186/S13029-019-0075-3  0.457
2019 Ravikumar A, Ramakrishnan C, Srinivasan N. Stereochemical Assessment of (φ,ψ) Outliers in Protein Structures Using Bond Geometry-Specific Ramachandran Steric-Maps. Structure (London, England : 1993). PMID 31607615 DOI: 10.1016/J.Str.2019.09.009  0.347
2019 Janaki C, Malini M, Tyagi N, Srinivasan N. Unity and diversity among viral kinases. Gene. 144134. PMID 31589960 DOI: 10.1016/J.Gene.2019.144134  0.342
2019 Vetrivel I, de Brevern AG, Cadet F, Srinivasan N, Offmann B. Structural variations within proteins can be as large as variations observed across their homologues. Biochimie. PMID 31560932 DOI: 10.1016/J.Biochi.2019.09.013  0.48
2019 Naveenkumar N, Sowdhamini R, Srinivasan N. Specialized structural and functional roles of residues selectively conserved in subfamilies of the pleckstrin homology domain family. Febs Open Bio. PMID 31436855 DOI: 10.1002/2211-5463.12725  0.439
2019 Narwani TJ, Etchebest C, Craveur P, Léonard S, Rebehmed J, Srinivasan N, Bornot A, Gelly JC, de Brevern AG. in silico prediction of protein flexibility with local structure approach. Biochimie. PMID 31377194 DOI: 10.1016/J.Biochi.2019.07.025  0.41
2019 Jairaj Narwani T, Craveur P, Shinada NK, Floch A, Santuz H, Melarkode Vattekatte A, Srinivasan N, Rebehmed J, Gelly JC, Etchebest C, de Brevern AG. Discrete analyses of protein dynamics. Journal of Biomolecular Structure & Dynamics. 1-23. PMID 31361191 DOI: 10.1080/07391102.2019.1650112  0.411
2019 Kidwai S, Bouzeyen R, Chakraborti S, Khare N, Das S, Gosain TP, Behura A, Meena CL, Dhiman R, Essafi M, Bajaj A, Saini DK, Srinivasan N, Mahajan D, Singh R. NU-6027 inhibits growth of by targeting Protein Kinase D and Protein Kinase G. Antimicrobial Agents and Chemotherapy. PMID 31285226 DOI: 10.1128/Aac.00996-19  0.378
2019 Naveenkumar N, Kumar G, Sowdhamini R, Srinivasan N, Vishwanath S. Fold combinations in multi-domain proteins. Bioinformation. 15: 342-350. PMID 31249437 DOI: 10.6026/97320630015342  0.453
2019 Tandon H, Sharma A, Sandhya S, Srinivasan N, Singh R. Mycobacterium tuberculosis Rv0366c-Rv0367c encodes a non-canonical PezAT-like toxin-antitoxin pair. Scientific Reports. 9: 1163. PMID 30718534 DOI: 10.1038/S41598-018-37473-Y  0.36
2019 Jayashree S, Murugavel P, Sowdhamini R, Srinivasan N. Interface residues of transient protein-protein complexes have extensive intra-protein interactions apart from inter-protein interactions. Biology Direct. 14: 1. PMID 30646935 DOI: 10.1186/S13062-019-0232-2  0.463
2019 Chakraborti S, Ramakrishnan G, Srinivasan N. Repurposing Drugs Based on Evolutionary Relationships Between Targets of Approved Drugs and Proteins of Interest. Methods in Molecular Biology (Clifton, N.J.). 1903: 45-59. PMID 30547435 DOI: 10.1007/978-1-4939-8955-3_3  0.602
2018 Kalaivani R, Narwani TJ, de Brevern AG, Srinivasan N. Long-range molecular dynamics show that inactive forms of Protein Kinase A are more dynamic than active forms. Protein Science : a Publication of the Protein Society. PMID 30468265 DOI: 10.1002/Pro.3556  0.35
2018 Kumar G, Mudgal R, Srinivasan N, Sandhya S. Use of designed sequences in protein structure recognition. Biology Direct. 13: 8. PMID 29776380 DOI: 10.1186/S13062-018-0209-6  0.486
2018 Mehrotra P, Ami VKG, Srinivasan N. Clustering of multi-domain protein sequences. Proteins. PMID 29675880 DOI: 10.1002/Prot.25510  0.44
2018 Bhagavat R, Sankar S, Srinivasan N, Chandra N. An Augmented Pocketome: Detection and Analysis of Small-Molecule Binding Pockets in Proteins of Known 3D Structure. Structure (London, England : 1993). 26: 499-512.e2. PMID 29514079 DOI: 10.1016/J.Str.2018.02.001  0.459
2018 Kalaivani R, Reema R, Srinivasan N. Recognition of sites of functional specialisation in all known eukaryotic protein kinase families. Plos Computational Biology. 14: e1005975. PMID 29438395 DOI: 10.1371/Journal.Pcbi.1005975  0.354
2018 Vishwanath S, de Brevern AG, Srinivasan N. Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains. Plos Computational Biology. 14: e1006008. PMID 29432415 DOI: 10.1371/Journal.Pcbi.1006008  0.443
2017 Vetrivel I, Mahajan S, Tyagi M, Hoffmann L, Sanejouand YH, Srinivasan N, de Brevern AG, Cadet F, Offmann B. Knowledge-based prediction of protein backbone conformation using a structural alphabet. Plos One. 12: e0186215. PMID 29161266 DOI: 10.1371/Journal.Pone.0186215  0.489
2017 Bhagavat R, Kim HB, Kim CY, Terwilliger TC, Mehta D, Srinivasan N, Chandra N. A genome-wide structure-based survey of nucleotide binding proteins in M. tuberculosis. Scientific Reports. 7: 12489. PMID 28970579 DOI: 10.1038/S41598-017-12471-8  0.399
2017 Ramakrishnan G, Chandra N, Srinivasan N. Exploring anti-malarial potential of FDA approved drugs: an in silico approach. Malaria Journal. 16: 290. PMID 28720135 DOI: 10.1186/S12936-017-1937-2  0.575
2017 Hatti K, Mathiharan YK, Srinivasan N, Murthy MRN. Seeing but not believing: the structure of glycerol dehydrogenase initially assumed to be the structure of a survival protein from Salmonella typhimurium. Acta Crystallographica. Section D, Structural Biology. 73: 609-617. PMID 28695861 DOI: 10.1107/S2059798317007677  0.454
2017 Bhagavat R, Srinivasan N, Chandra N. Deciphering common recognition principles of nucleoside mono/di/and tri-phosphates binding in diverse proteins via structural matching of their binding sites. Proteins. PMID 28547747 DOI: 10.1002/Prot.25328  0.365
2017 Rakesh R, Krishnan R, Sattlegger E, Srinivasan N. Recognition of a structural domain (RWDBD) in Gcn1 proteins that interacts with the RWD domain containing proteins. Biology Direct. 12: 12. PMID 28526057 DOI: 10.1186/S13062-017-0184-3  0.467
2017 Mudgal R, Srinivasan N, Chandra N. Resolving protein structure-function-binding site relationships from a binding site similarity network perspective. Proteins. PMID 28342236 DOI: 10.1002/Prot.25293  0.41
2017 Mehrotra P, Ramakrishnan G, Dhandapani G, Srinivasan N, Madanan MG. Comparison of Leptospira interrogans and Leptospira biflexa genomes: analysis of potential leptospiral-host interactions. Molecular Biosystems. PMID 28294222 DOI: 10.1039/C6Mb00856A  0.635
2017 Hatti K, Biswas A, Choudhary S, Dadireddy V, Sekar K, Srinivasan N, Murthy MR. Structure determination of contaminant proteins using the MarathonMR procedure. Journal of Structural Biology. PMID 28167161 DOI: 10.1016/J.Jsb.2017.01.005  0.464
2017 Vishwanath S, Sukhwal A, Sowdhamini R, Srinivasan N. Specificity and stability of transient protein-protein interactions. Current Opinion in Structural Biology. 44: 77-86. PMID 28088083 DOI: 10.1016/J.Sbi.2016.12.010  0.428
2016 Hatti K, Gulati A, Srinivasan N, Murthy MR. Determination of crystal structures of proteins of unknown identity using a marathon molecular replacement procedure: structure of Stenotrophomonas maltophilia phosphate-binding protein. Acta Crystallographica. Section D, Structural Biology. 72: 1081-1089. PMID 27710929 DOI: 10.1107/S2059798316012419  0.386
2016 Rakesh R, Joseph AP, Bhaskara RM, Srinivasan N. Structural and mechanistic insights into human splicing factor SF3b complex derived using an integrated approach guided by the cryo-EM density maps. Rna Biology. 1-16. PMID 27618338 DOI: 10.1080/15476286.2016.1218590  0.393
2016 Joseph AP, Swapna LS, Rakesh R, Srinivasan N. Use of evolutionary information in the fitting of atomic level protein models in low resolution cryo-EM map of a protein assembly improves the accuracy of the fitting. Journal of Structural Biology. PMID 27444391 DOI: 10.1016/J.Jsb.2016.07.012  0.361
2016 Ramakrishnan G, Jain A, Chandra N, Srinivasan N. Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria. Biology Direct. 11: 27. PMID 27246835 DOI: 10.1186/S13062-016-0130-9  0.686
2016 Sudha G, Srinivasan N. Comparative analyses of quaternary arrangements in homo-oligomeric proteins in superfamilies: Functional implications. Proteins. PMID 27177429 DOI: 10.1002/Prot.25065  0.458
2016 Janaki C, Srinivasan N, Manoharan M. Classification of Protein Kinases Influenced by Conservation of Substrate Binding Residues. Methods in Molecular Biology (Clifton, N.J.). 1415: 301-13. PMID 27115639 DOI: 10.1007/978-1-4939-3572-7_15  0.344
2016 Rakesh R, Srinivasan N. Improving the Accuracy of Fitted Atomic Models in Cryo-EM Density Maps of Protein Assemblies Using Evolutionary Information from Aligned Homologous Proteins. Methods in Molecular Biology (Clifton, N.J.). 1415: 193-209. PMID 27115634 DOI: 10.1007/978-1-4939-3572-7_10  0.412
2016 Kalaivani R, de Brevern AG, Srinivasan N. Conservation of structural fluctuations in homologous protein kinases and its implications on functional sites. Proteins. PMID 27028938 DOI: 10.1002/Prot.25044  0.416
2016 Das M, Bhosale M, Wadhwa N, Ahmed SM, Bhaskarla C, Kumar A, Srinivasan N, Nandi D. Importance of Amino Acids, Gln-119 and Tyr-376, in the S1 Pocket of Escherichia coli Peptidase N in Determining Substrate Specificity. Protein and Peptide Letters. PMID 26927617 DOI: 10.2174/0929866523666160301122553  0.355
2016 Sandhya S, Mudgal R, Kumar G, Sowdhamini R, Srinivasan N. Protein sequence design and its applications. Current Opinion in Structural Biology. 37: 71-80. PMID 26773478 DOI: 10.1016/J.Sbi.2015.12.004  0.417
2015 Ramakrishnan G, Srinivasan N, Padmapriya P, Natarajan V. Homology-Based Prediction of Potential Protein-Protein Interactions between Human Erythrocytes and Plasmodium falciparum. Bioinformatics and Biology Insights. 9: 195-206. PMID 26740742 DOI: 10.4137/Bbi.S31880  0.643
2015 Ramakrishnan G, Chandra NR, Srinivasan N. Recognizing drug targets using evolutionary information: implications for repurposing FDA-approved drugs against Mycobacterium tuberculosis H37Rv. Molecular Biosystems. PMID 26429199 DOI: 10.1039/C5Mb00476D  0.601
2015 Sudha G, Singh P, Swapna LS, Srinivasan N. Weak conservation of structural features in the interfaces of homologous transient protein-protein complexes. Protein Science : a Publication of the Protein Society. 24: 1856-73. PMID 26311309 DOI: 10.1002/Pro.2792  0.452
2015 Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ, Craik DJ, Finn RD, Gloriam D, Haft DH, Henrissat B, Holliday GL, Isberg V, Kaas Q, Landsman D, ... ... Srinivasan N, et al. Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database : the Journal of Biological Databases and Curation. 2015: bav063. PMID 26284514 DOI: 10.1093/Database/Bav063  0.374
2015 Lakshmi B, Mishra M, Srinivasan N, Archunan G. Structure-Based Phylogenetic Analysis of the Lipocalin Superfamily. Plos One. 10: e0135507. PMID 26263546 DOI: 10.1371/Journal.Pone.0135507  0.452
2015 Mudgal R, Sandhya S, Chandra N, Srinivasan N. De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods. Biology Direct. 10: 38. PMID 26228684 DOI: 10.1186/S13062-015-0069-2  0.454
2015 Sudha G, Naveenkumar N, Srinivasan N. Evolutionary and structural analyses of heterodimeric proteins composed of subunits with same fold. Proteins. 83: 1766-86. PMID 26148218 DOI: 10.1002/Prot.24849  0.477
2015 Metri R, Hariharaputran S, Ramakrishnan G, Anand P, Raghavender US, Ochoa-Montaño B, Higueruelo AP, Sowdhamini R, Chandra NR, Blundell TL, Srinivasan N. SInCRe-structural interactome computational resource for Mycobacterium tuberculosis. Database : the Journal of Biological Databases and Curation. 2015. PMID 26130660 DOI: 10.1093/Database/Bav060  0.8
2015 Mehrotra P, Bhaskara RM, Gnanavel M, Rakshambikai R, Martin J, Srinivasan N. 168 Classification of protein sequences with special references to multi-domain systems. Journal of Biomolecular Structure & Dynamics. 33: 110. PMID 26103379 DOI: 10.1080/07391102.2015.1032805  0.409
2015 Srinivasan N, Mudgal R, Kumar G, Chandra NR, Sowdhamini R, Sandhya S. 161 Bridging the islands of protein families in sequence space using artificial sequences. Journal of Biomolecular Structure & Dynamics. 33: 103-4. PMID 26103370 DOI: 10.1080/07391102.2015.1032798  0.37
2015 Craveur P, Joseph AP, Esque J, Narwani TJ, Noël F, Shinada N, Goguet M, Leonard S, Poulain P, Bertrand O, Faure G, Rebehmed J, Ghozlane A, Swapna LS, Bhaskara RM, ... ... Srinivasan N, et al. Protein flexibility in the light of structural alphabets. Frontiers in Molecular Biosciences. 2: 20. PMID 26075209 DOI: 10.3389/Fmolb.2015.00020  0.498
2015 Holliday GL, Bairoch A, Bagos PG, Chatonnet A, Craik DJ, Finn RD, Henrissat B, Landsman D, Manning G, Nagano N, O'Donovan C, Pruitt KD, Rawlings ND, Saier M, Sowdhamini R, ... ... Srinivasan N, et al. Key challenges for the creation and maintenance of specialist protein resources. Proteins. 83: 1005-13. PMID 25820941 DOI: 10.1002/Prot.24803  0.426
2015 Bhat P, Shwetha S, Sharma DK, Joseph AP, Srinivasan N, Das S. The beta hairpin structure within ribosomal protein S5 mediates interplay between domains II and IV and regulates HCV IRES function. Nucleic Acids Research. 43: 2888-901. PMID 25712089 DOI: 10.1093/Nar/Gkv110  0.356
2015 Kalaivani R, Srinivasan N. A Gaussian network model study suggests that structural fluctuations are higher for inactive states than active states of protein kinases. Molecular Biosystems. 11: 1079-95. PMID 25635939 DOI: 10.1039/C4Mb00675E  0.39
2015 Ramakrishnan G, Ochoa-Montaño B, Raghavender US, Mudgal R, Joshi AG, Chandra NR, Sowdhamini R, Blundell TL, Srinivasan N. Enriching the annotation of Mycobacterium tuberculosis H37Rv proteome using remote homology detection approaches: insights into structure and function. Tuberculosis (Edinburgh, Scotland). 95: 14-25. PMID 25467293 DOI: 10.1016/J.Tube.2014.10.009  0.736
2015 Mahajan S, de Brevern AG, Sanejouand YH, Srinivasan N, Offmann B. Use of a structural alphabet to find compatible folds for amino acid sequences. Protein Science : a Publication of the Protein Society. 24: 145-53. PMID 25297700 DOI: 10.1002/Pro.2581  0.472
2015 Mudgal R, Sandhya S, Kumar G, Sowdhamini R, Chandra NR, Srinivasan N. NrichD database: sequence databases enriched with computationally designed protein-like sequences aid in remote homology detection. Nucleic Acids Research. 43: D300-5. PMID 25262355 DOI: 10.1093/Nar/Gku888  0.426
2015 Rakshambikai R, Manoharan M, Gnanavel M, Srinivasan N. Typical and atypical domain combinations in human protein kinases: Functions, disease causing mutations and conservation in other primates Rsc Advances. 5: 25132-25148. DOI: 10.1039/C4Ra11685B  0.365
2015 Sudha G, Naveenkumar N, Srinivasan N. Evolutionary and structural analyses of heterodimeric proteins composed of subunits with same fold Proteins: Structure, Function and Bioinformatics. 83: 1766-1786. DOI: 10.1002/prot.24849  0.38
2014 Ramakrishnan G, Chandra NR, Srinivasan N. From workstations to workbenches: Towards predicting physicochemically viable protein-protein interactions across a host and a pathogen. Iubmb Life. 66: 759-74. PMID 25512108 DOI: 10.1002/Iub.1331  0.687
2014 Gnanavel M, Mehrotra P, Rakshambikai R, Martin J, Srinivasan N, Bhaskara RM. CLAP: a web-server for automatic classification of proteins with special reference to multi-domain proteins. Bmc Bioinformatics. 15: 343. PMID 25282152 DOI: 10.1186/1471-2105-15-343  0.499
2014 Joseph AP, Bhat P, Das S, Srinivasan N. Re-analysis of cryoEM data on HCV IRES bound to 40S subunit of human ribosome integrated with recent structural information suggests new contact regions between ribosomal proteins and HCV RNA. Rna Biology. 11: 891-905. PMID 25268799 DOI: 10.4161/Rna.29545  0.412
2014 Rakshambikai R, Gnanavel M, Srinivasan N. Hybrid and rogue kinases encoded in the genomes of model eukaryotes. Plos One. 9: e107956. PMID 25255313 DOI: 10.1371/Journal.Pone.0107956  0.346
2014 Vishwanath S, Srinivasan N. Chemical specificity and conformational flexibility in proteinase-inhibitor interaction: scaffolds for promiscuous binding. Progress in Biophysics and Molecular Biology. 116: 151-7. PMID 25151636 DOI: 10.1016/J.Pbiomolbio.2014.08.003  0.509
2014 Sudha G, Nussinov R, Srinivasan N. An overview of recent advances in structural bioinformatics of protein-protein interactions and a guide to their principles. Progress in Biophysics and Molecular Biology. 116: 141-50. PMID 25077409 DOI: 10.1016/J.Pbiomolbio.2014.07.004  0.49
2014 Lakshmi B, Sinduja C, Archunan G, Srinivasan N. Ramachandran analysis of conserved glycyl residues in homologous proteins of known structure. Protein Science : a Publication of the Protein Society. 23: 843-50. PMID 24687432 DOI: 10.1002/Pro.2468  0.462
2014 Bhaskara RM, Mehrotra P, Rakshambikai R, Gnanavel M, Martin J, Srinivasan N. The relationship between classification of multi-domain proteins using an alignment-free approach and their functions: a case study with immunoglobulins. Molecular Biosystems. 10: 1082-93. PMID 24572770 DOI: 10.1039/C3Mb70443B  0.474
2014 Rakshambikai R, Srinivasan N, Gadkari RA. Repertoire of protein kinases encoded in the genome of zebrafish shows remarkably large population of PIM kinases. Journal of Bioinformatics and Computational Biology. 12: 1350014. PMID 24467753 DOI: 10.1142/S0219720013500145  0.325
2014 Bhaskara RM, Padhi A, Srinivasan N. Accurate prediction of interfacial residues in two-domain proteins using evolutionary information: implications for three-dimensional modeling. Proteins. 82: 1219-34. PMID 24375512 DOI: 10.1002/Prot.24486  0.443
2014 Mudgal R, Sowdhamini R, Chandra N, Srinivasan N, Sandhya S. Filling-in void and sparse regions in protein sequence space by protein-like artificial sequences enables remarkable enhancement in remote homology detection capability. Journal of Molecular Biology. 426: 962-79. PMID 24316367 DOI: 10.1016/J.Jmb.2013.11.026  0.448
2014 Lakshmi B, Ramakrishnan C, Archunan G, Sowdhamini R, Srinivasan N. Investigations of Ramachandran disallowed conformations in protein domain families. International Journal of Biological Macromolecules. 63: 119-25. PMID 24184732 DOI: 10.1016/J.Ijbiomac.2013.10.032  0.485
2014 Mahajan S, de Brevern AG, Offmann B, Srinivasan N. Correlation between local structural dynamics of proteins inferred from NMR ensembles and evolutionary dynamics of homologues of known structure. Journal of Biomolecular Structure & Dynamics. 32: 751-8. PMID 23730714 DOI: 10.1080/07391102.2013.789989  0.433
2014 Léonard S, Joseph AP, Srinivasan N, Gelly JC, de Brevern AG. mulPBA: an efficient multiple protein structure alignment method based on a structural alphabet. Journal of Biomolecular Structure & Dynamics. 32: 661-8. PMID 23659291 DOI: 10.1080/07391102.2013.787026  0.456
2014 Joseph AP, Gelly J, Leonard S, Craveur P, Esque J, Faure G, Rebehmed J, Etchebest C, Srinivasan N, de Brevern AG. Efficient Protein Structure Alignment Methods Based on a Structural Alphabet Biophysical Journal. 106: 54a. DOI: 10.1016/J.Bpj.2013.11.381  0.465
2013 Rakshambikai R, Srinivasan N, Nishant KT. Structural insights into Saccharomyces cerevisiae Msh4-Msh5 complex function using homology modeling. Plos One. 8: e78753. PMID 24244354 DOI: 10.1371/Journal.Pone.0078753  0.377
2013 Vendra VP, Agarwal G, Chandani S, Talla V, Srinivasan N, Balasubramanian D. Structural integrity of the Greek key motif in βγ-crystallins is vital for central eye lens transparency. Plos One. 8: e70336. PMID 23936409 DOI: 10.1371/Journal.Pone.0070336  0.328
2013 Mahajan S, Agarwal G, Iftekhar M, Offmann B, de Brevern AG, Srinivasan N. DoSA: Database of Structural Alignments. Database : the Journal of Biological Databases and Curation. 2013: bat048. PMID 23846594 DOI: 10.1093/Database/Bat048  0.5
2013 Hansen AM, Chaerkady R, Sharma J, Díaz-Mejía JJ, Tyagi N, Renuse S, Jacob HK, Pinto SM, Sahasrabuddhe NA, Kim MS, Delanghe B, Srinivasan N, Emili A, Kaper JB, Pandey A. The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence. Plos Pathogens. 9: e1003403. PMID 23785281 DOI: 10.1371/Journal.Ppat.1003403  0.35
2013 Tyagi N, Srinivasan N. Recognition of nontrivial remote homology relationships involving proteins of Helicobacter pylori: implications for function recognition. Methods in Molecular Biology (Clifton, N.J.). 993: 155-75. PMID 23568470 DOI: 10.1007/978-1-62703-342-8_11  0.444
2013 Kaushik S, Mutt E, Chellappan A, Sankaran S, Srinivasan N, Sowdhamini R. Improved detection of remote homologues using cascade PSI-BLAST: influence of neighbouring protein families on sequence coverage. Plos One. 8: e56449. PMID 23437136 DOI: 10.1371/Journal.Pone.0056449  0.404
2013 Gabriel N, Hareendran S, Sen D, Gadkari RA, Sudha G, Selot R, Hussain M, Dhaksnamoorthy R, Samuel R, Srinivasan N, Srivastava A, Jayandharan GR. Bioengineering of AAV2 capsid at specific serine, threonine, or lysine residues improves its transduction efficiency in vitro and in vivo. Human Gene Therapy Methods. 24: 80-93. PMID 23379478 DOI: 10.1089/Hgtb.2012.194  0.361
2013 Bhaskara RM, de Brevern AG, Srinivasan N. Understanding the role of domain-domain linkers in the spatial orientation of domains in multi-domain proteins. Journal of Biomolecular Structure & Dynamics. 31: 1467-80. PMID 23249395 DOI: 10.1080/07391102.2012.743438  0.381
2012 Swapna LS, Srinivasan N, Robertson DL, Lovell SC. The origins of the evolutionary signal used to predict protein-protein interactions. Bmc Evolutionary Biology. 12: 238. PMID 23217198 DOI: 10.1186/1471-2148-12-238  0.453
2012 Sudha G, Yamunadevi S, Tyagi N, Das S, Srinivasan N. Structural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR. Bmc Structural Biology. 12: 28. PMID 23148689 DOI: 10.1186/1472-6807-12-28  0.373
2012 Joseph AP, Valadié H, Srinivasan N, de Brevern AG. Local structural differences in homologous proteins: specificities in different SCOP classes. Plos One. 7: e38805. PMID 22745680 DOI: 10.1371/Journal.Pone.0038805  0.469
2012 Sandhya S, Mudgal R, Jayadev C, Abhinandan KR, Sowdhamini R, Srinivasan N. Cascaded walks in protein sequence space: use of artificial sequences in remote homology detection between natural proteins. Molecular Biosystems. 8: 2076-84. PMID 22692068 DOI: 10.1039/C2Mb25113B  0.412
2012 Joseph AP, Srinivasan N, de Brevern AG. Progressive structure-based alignment of homologous proteins: Adopting sequence comparison strategies. Biochimie. 94: 2025-34. PMID 22676903 DOI: 10.1016/J.Biochi.2012.05.028  0.48
2012 Rakshambikai R, Yamunadevi S, Anamika K, Tyagi N, Srinivasan N. Repertoire of Protein Kinases Encoded in the Genome of Takifugu rubripes. Comparative and Functional Genomics. 2012: 258284. PMID 22666085 DOI: 10.1155/2012/258284  0.408
2012 Swapna LS, Srikeerthana K, Srinivasan N. Extent of structural asymmetry in homodimeric proteins: prevalence and relevance. Plos One. 7: e36688. PMID 22629324 DOI: 10.1371/Journal.Pone.0036688  0.385
2012 Swapna LS, Mahajan S, de Brevern AG, Srinivasan N. Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins. Bmc Structural Biology. 12: 6. PMID 22554255 DOI: 10.1186/1472-6807-12-6  0.479
2012 Swapna LS, Bhaskara RM, Sharma J, Srinivasan N. Roles of residues in the interface of transient protein-protein complexes before complexation. Scientific Reports. 2: 334. PMID 22451863 DOI: 10.1038/Srep00334  0.495
2012 Chawla B, Kumar RR, Tyagi N, Subramanian G, Srinivasan N, Park MH, Madhubala R. A unique modification of the eukaryotic initiation factor 5A shows the presence of the complete hypusine pathway in Leishmania donovani. Plos One. 7: e33138. PMID 22438895 DOI: 10.1371/Journal.Pone.0033138  0.404
2012 Gadkari RA, Srinivasan N. Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces. Plos One. 7: e31445. PMID 22384024 DOI: 10.1371/Journal.Pone.0031445  0.476
2012 Amarnath S, Kawli T, Mohanty S, Srinivasan N, Nanjundiah V. Pleiotropic roles of a ribosomal protein in Dictyostelium discoideum. Plos One. 7: e30644. PMID 22363460 DOI: 10.1371/Journal.Pone.0030644  0.424
2012 Swapna LS, Rekha N, Srinivasan N. Accommodation of profound sequence differences at the interfaces of eubacterial RNA polymerase multi-protein assembly. Bioinformation. 8: 6-12. PMID 22359428 DOI: 10.6026/97320630008006  0.36
2012 Joseph AP, Srinivasan N, de Brevern AG. Cis-trans peptide variations in structurally similar proteins. Amino Acids. 43: 1369-81. PMID 22227866 DOI: 10.1007/S00726-011-1211-9  0.391
2011 Bhaskara RM, Srinivasan N. Stability of domain structures in multi-domain proteins. Scientific Reports. 1: 40. PMID 22355559 DOI: 10.1038/Srep00040  0.368
2011 Krishnadev O, Srinivasan N. AlignHUSH: alignment of HMMs using structure and hydrophobicity information. Bmc Bioinformatics. 12: 275. PMID 21729312 DOI: 10.1186/1471-2105-12-275  0.437
2011 Gelly JC, Joseph AP, Srinivasan N, de Brevern AG. iPBA: a tool for protein structure comparison using sequence alignment strategies. Nucleic Acids Research. 39: W18-23. PMID 21586582 DOI: 10.1093/Nar/Gkr333  0.447
2011 Joseph AP, Srinivasan N, de Brevern AG. Improvement of protein structure comparison using a structural alphabet. Biochimie. 93: 1434-45. PMID 21569819 DOI: 10.1016/J.Biochi.2011.04.010  0.503
2011 Agarwal G, Mahajan S, Srinivasan N, de Brevern AG. Identification of local conformational similarity in structurally variable regions of homologous proteins using protein blocks. Plos One. 6: e17826. PMID 21445259 DOI: 10.1371/Journal.Pone.0017826  0.49
2011 Krishnadev O, Srinivasan N. Prediction of protein-protein interactions between human host and a pathogen and its application to three pathogenic bacteria. International Journal of Biological Macromolecules. 48: 613-9. PMID 21310175 DOI: 10.1016/J.Ijbiomac.2011.01.030  0.415
2011 Srinivasan N, Agarwal G, Bhaskara RM, Gadkari R, Krishnadev O, Lakshmi B, Mahajan S, Mohanty S, Mudgal R, Rakshambikai R, Sandhya S, Sudha G, Swapna L, Tyagi N. Influence of Genomic and Other Biological Data Sets in the Understanding of Protein Structures, Functions and Interactions International Journal of Knowledge Discovery in Bioinformatics. 2: 24-44. DOI: 10.4018/Jkdb.2011010102  0.502
2010 Joseph AP, Agarwal G, Mahajan S, Gelly JC, Swapna LS, Offmann B, Cadet F, Bornot A, Tyagi M, Valadié H, Schneider B, Etchebest C, Srinivasan N, De Brevern AG. A short survey on protein blocks. Biophysical Reviews. 2: 137-147. PMID 21731588 DOI: 10.1007/S12551-010-0036-1  0.463
2010 Martin J, Anamika K, Srinivasan N. Classification of protein kinases on the basis of both kinase and non-kinase regions. Plos One. 5: e12460. PMID 20856812 DOI: 10.1371/Journal.Pone.0012460  0.428
2010 Gadkari RA, Srinivasan N. Prediction of protein-protein interactions in dengue virus coat proteins guided by low resolution cryoEM structures. Bmc Structural Biology. 10: 17. PMID 20550721 DOI: 10.1186/1472-6807-10-17  0.437
2010 Tyagi N, Anamika K, Srinivasan N. A framework for classification of prokaryotic protein kinases. Plos One. 5: e10608. PMID 20520783 DOI: 10.1371/Journal.Pone.0010608  0.411
2010 Aggarwal P, Das Gupta M, Joseph AP, Chatterjee N, Srinivasan N, Nath U. Identification of specific DNA binding residues in the TCP family of transcription factors in Arabidopsis. The Plant Cell. 22: 1174-89. PMID 20363772 DOI: 10.1105/Tpc.109.066647  0.35
2010 Deshmukh K, Anamika K, Srinivasan N. Evolution of domain combinations in protein kinases and its implications for functional diversity. Progress in Biophysics and Molecular Biology. 102: 1-15. PMID 20026163 DOI: 10.1016/J.Pbiomolbio.2009.12.009  0.44
2010 Kandathil AJ, Joseph AP, Kannangai R, Srinivasan N, Abraham OC, Pulimood SA, Sridharan G. HIV reverse transcriptase: structural interpretation of drug resistant genetic variants from India. Bioinformation. 4: 36-45. PMID 20011151 DOI: 10.6026/97320630004036  0.347
2010 Chawla B, Jhingran A, Singh S, Tyagi N, Park MH, Srinivasan N, Roberts SC, Madhubala R. Identification and characterization of a novel deoxyhypusine synthase in Leishmania donovani. The Journal of Biological Chemistry. 285: 453-63. PMID 19880510 DOI: 10.1074/Jbc.M109.048850  0.382
2010 Krishnadev O, Bisht S, Srinivasan N. Prediction of Protein-Protein Interactions Between Human Host and Two Mycobacterial Organisms International Journal of Knowledge Discovery in Bioinformatics. 1: 1-13. DOI: 10.4018/Jkdb.2010100201  0.452
2009 Anamika K, Garnier N, Srinivasan N. Functional diversity of human protein kinase splice variants marks significant expansion of human kinome. Bmc Genomics. 10: 622. PMID 20028505 DOI: 10.1186/1471-2164-10-622  0.391
2009 Tyagi N, Krishnadev O, Srinivasan N. Prediction of protein-protein interactions between Helicobacter pylori and a human host. Molecular Biosystems. 5: 1630-5. PMID 20023722 DOI: 10.1039/B906543C  0.389
2009 Anamika K, Abhinandan KR, Deshmukh K, Srinivasan N. Classification of nonenzymatic homologues of protein kinases. Comparative and Functional Genomics. 365637. PMID 19809514 DOI: 10.1155/2009/365637  0.484
2009 Mohanty S, Srinivasan N. Identification of "missing" metabolic proteins of Plasmodium falciparum: a bioinformatics approach. Protein and Peptide Letters. 16: 961-8. PMID 19689423 DOI: 10.2174/092986609788923257  0.431
2009 Roy A, Srinivasan N, Gowri VS. Molecular and structural basis of drift in the functions of closely-related homologous enzyme domains: implications for function annotation based on homology searches and structural genomics. In Silico Biology. 9: S41-55. PMID 19537164 DOI: 10.3233/Isb-2009-0379  0.451
2009 Kumar A, Bhosale M, Reddy S, Srinivasan N, Nandi D. Importance of non-conserved distal carboxyl terminal amino acids in two peptidases belonging to the M1 family: Thermoplasma acidophilum Tricorn interacting factor F2 and Escherichia coli Peptidase N. Biochimie. 91: 1145-55. PMID 19527767 DOI: 10.1016/J.Biochi.2009.06.002  0.37
2009 Tyagi N, Swapna LS, Mohanty S, Agarwal G, Gowri VS, Anamika K, Priya ML, Krishnadev O, Srinivasan N. Evolutionary divergence of Plasmodium falciparum: sequences, protein-protein interactions, pathways and processes. Infectious Disorders Drug Targets. 9: 257-71. PMID 19519480 DOI: 10.2174/1871526510909030257  0.457
2009 Agarwal G, Rajavel M, Gopal B, Srinivasan N. Structure-based phylogeny as a diagnostic for functional characterization of proteins with a cupin fold. Plos One. 4: e5736. PMID 19478949 DOI: 10.1371/Journal.Pone.0005736  0.482
2009 Kandathil AJ, Joseph AP, Kannangai R, Srinivasan N, Abraham OC, Pulimood SA, Sridharan G. Structural basis of drug resistance by genetic variants of HIV type 1 clade c protease from India. Aids Research and Human Retroviruses. 25: 511-9. PMID 19400736 DOI: 10.1089/Aid.2008.0102  0.349
2009 Kumar A, Reddy S, Srinivasan N, Nandi D. Interaction between two residues in the inter-domain interface of Escherichia coli peptidase N modulates catalytic activity. Protein and Peptide Letters. 16: 415-22. PMID 19356140 DOI: 10.2174/092986609787848081  0.349
2009 Sandhya S, Rani SS, Pankaj B, Govind MK, Offmann B, Srinivasan N, Sowdhamini R. Length variations amongst protein domain superfamilies and consequences on structure and function. Plos One. 4: e4981. PMID 19333395 DOI: 10.1371/Journal.Pone.0004981  0.454
2009 Gadkari RA, Varughese D, Srinivasan N. Recognition of interaction interface residues in low-resolution structures of protein assemblies solely from the positions of C(alpha) atoms. Plos One. 4: e4476. PMID 19214247 DOI: 10.1371/Journal.Pone.0004476  0.393
2009 Rath J, Gowri VS, Chauhan SC, Padmanabhan PK, Srinivasan N, Madhubala R. A glutathione-specific aldose reductase of Leishmania donovani and its potential implications for methylglyoxal detoxification pathway. Gene. 429: 1-9. PMID 18983902 DOI: 10.1016/J.Gene.2008.09.037  0.426
2009 Ramakrishnan C, Srinivasan N, Prashanth D. Conformation of glycyl residues in globular proteins International Journal of Peptide and Protein Research. 29: 629-637. PMID 3610477 DOI: 10.1111/J.1399-3011.1987.Tb02293.X  0.336
2008 Thangudu RR, Manoharan M, Srinivasan N, Cadet F, Sowdhamini R, Offmann B. Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families. Bmc Structural Biology. 8: 55. PMID 19111067 DOI: 10.1186/1472-6807-8-55  0.512
2008 Anamika K, Martin J, Srinivasan N. Comparative kinomics of human and chimpanzee reveal unique kinship and functional diversity generated by new domain combinations. Bmc Genomics. 9: 625. PMID 19105813 DOI: 10.1186/1471-2164-9-625  0.36
2008 Sandhya S, Pankaj B, Govind MK, Offmann B, Srinivasan N, Sowdhamini R. CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations. Bmc Structural Biology. 8: 28. PMID 18513436 DOI: 10.1186/1472-6807-8-28  0.488
2008 Pantakani DV, Swapna LS, Srinivasan N, Mannan AU. Spastin oligomerizes into a hexamer and the mutant spastin (E442Q) redistribute the wild-type spastin into filamentous microtubule. Journal of Neurochemistry. 106: 613-24. PMID 18410514 DOI: 10.1111/J.1471-4159.2008.05414.X  0.464
2008 Tyagi M, de Brevern AG, Srinivasan N, Offmann B. Protein structure mining using a structural alphabet. Proteins. 71: 920-37. PMID 18004784 DOI: 10.1002/Prot.21776  0.483
2008 Anamika K, Bhattacharya A, Srinivasan N. Analysis of the protein kinome of Entamoeba histolytica. Proteins. 71: 995-1006. PMID 18004777 DOI: 10.1002/Prot.21790  0.407
2007 Gowri VS, Anamika K, Gore S, Srinivasan N. Analysis on sliding helices and strands in protein structural comparisons: a case study with protein kinases. Journal of Biosciences. 32: 921-8. PMID 17914234 DOI: 10.1007/S12038-007-0092-2  0.488
2007 Ramakrishnan C, Lakshmi B, Kurien A, Devipriya D, Srinivasan N. Structural compromise of disallowed conformations in peptide and protein structures. Protein and Peptide Letters. 14: 672-82. PMID 17897093 DOI: 10.2174/092986607781483921  0.35
2007 Anamika K, Srinivasan N. Comparative kinomics of Plasmodium organisms: unity in diversity. Protein and Peptide Letters. 14: 509-17. PMID 17627589 DOI: 10.2174/092986607780989949  0.366
2007 Tina KG, Bhadra R, Srinivasan N. PIC: Protein Interactions Calculator. Nucleic Acids Research. 35: W473-6. PMID 17584791 DOI: 10.1093/Nar/Gkm423  0.414
2007 Balaji S, Srinivasan N. Comparison of sequence-based and structure-based phylogenetic trees of homologous proteins: Inferences on protein evolution. Journal of Biosciences. 32: 83-96. PMID 17426382 DOI: 10.1007/S12038-007-0008-1  0.502
2007 Gowri VS, Tina KG, Krishnadev O, Srinivasan N. Strategies for the effective identification of remotely related sequences in multiple PSSM search approach. Proteins. 67: 789-94. PMID 17380509 DOI: 10.1002/Prot.21356  0.313
2007 Thangudu RR, Sharma P, Srinivasan N, Offmann B. Analycys: a database for conservation and conformation of disulphide bonds in homologous protein domains. Proteins. 67: 255-61. PMID 17285632 DOI: 10.1002/Prot.21318  0.455
2006 Talla V, Narayanan C, Srinivasan N, Balasubramanian D. Mutation causing self-aggregation in human gammaC-crystallin leading to congenital cataract. Investigative Ophthalmology & Visual Science. 47: 5212-7. PMID 17122105 DOI: 10.1167/Iovs.06-0427  0.692
2006 Tyagi M, Gowri VS, Srinivasan N, de Brevern AG, Offmann B. A substitution matrix for structural alphabet based on structural alignment of homologous proteins and its applications. Proteins. 65: 32-9. PMID 16894618 DOI: 10.1002/Prot.21087  0.507
2006 Pugalenthi G, Shameer K, Srinivasan N, Sowdhamini R. HARMONY: a server for the assessment of protein structures. Nucleic Acids Research. 34: W231-4. PMID 16844999 DOI: 10.1093/Nar/Gkl314  0.462
2006 Bhadra R, Sandhya S, Abhinandan KR, Chakrabarti S, Sowdhamini R, Srinivasan N. Cascade PSI-BLAST web server: a remote homology search tool for relating protein domains. Nucleic Acids Research. 34: W143-6. PMID 16844978 DOI: 10.1093/Nar/Gkl157  0.437
2006 Tyagi M, Sharma P, Swamy CS, Cadet F, Srinivasan N, de Brevern AG, Offmann B. Protein Block Expert (PBE): a web-based protein structure analysis server using a structural alphabet. Nucleic Acids Research. 34: W119-23. PMID 16844973 DOI: 10.1093/Nar/Gkl199  0.497
2006 Krupa A, Anamika, Srinivasan N. Genome-wide comparative analyses of domain organisation of repertoires of protein kinases of Arabidopsis thaliana and Oryza sativa. Gene. 380: 1-13. PMID 16843620 DOI: 10.1016/J.Gene.2006.05.016  0.391
2006 Sharma K, Gupta M, Krupa A, Srinivasan N, Singh Y. EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis. The Febs Journal. 273: 2711-21. PMID 16817899 DOI: 10.1111/J.1742-4658.2006.05289.X  0.353
2006 Gowri VS, Krishnadev O, Swamy CS, Srinivasan N. MulPSSM: a database of multiple position-specific scoring matrices of protein domain families. Nucleic Acids Research. 34: D243-6. PMID 16381855 DOI: 10.1093/Nar/Gkj043  0.406
2006 Rekha N, Machado SM, Narayanan C, Krupa A, Srinivasan N. Interaction interfaces of protein domains are not topologically equivalent across families within superfamilies: Implications for metabolic and signaling pathways. Proteins. 58: 339-53. PMID 15562516 DOI: 10.1002/Prot.20319  0.472
2006 Srinivasan N, Krupa A. A genomic perspective of protein kinases in Plasmodium falciparum. Proteins. 58: 180-9. PMID 15515182 DOI: 10.1002/Prot.20278  0.424
2005 Padmanabhan PK, Mukherjee A, Singh S, Chattopadhyaya S, Gowri VS, Myler PJ, Srinivasan N, Madhubala R. Glyoxalase I from Leishmania donovani: a potential target for anti-parasite drug. Biochemical and Biophysical Research Communications. 337: 1237-48. PMID 16236261 DOI: 10.1016/J.Bbrc.2005.09.179  0.383
2005 Sandhya S, Chakrabarti S, Abhinandan KR, Sowdhamini R, Srinivasan N. Assessment of a rigorous transitive profile based search method to detect remotely similar proteins. Journal of Biomolecular Structure & Dynamics. 23: 283-98. PMID 16218755 DOI: 10.1080/07391102.2005.10507066  0.38
2005 Krupa A, Srinivasan N. Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes Bmc Genomics. 6. PMID 16171520 DOI: 10.1186/1471-2164-6-129  0.356
2005 De S, Krishnadev O, Srinivasan N, Rekha N. Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different. Bmc Structural Biology. 5: 15. PMID 16105176 DOI: 10.1186/1472-6807-5-15  0.408
2005 Krishnadev O, Rekha N, Pandit SB, Abhiman S, Mohanty S, Swapna LS, Gore S, Srinivasan N. PRODOC: a resource for the comparison of tethered protein domain architectures with in-built information on remotely related domain families. Nucleic Acids Research. 33: W126-9. PMID 15980440 DOI: 10.1093/Nar/Gki474  0.453
2005 Anand B, Gowri VS, Srinivasan N. Use of multiple profiles corresponding to a sequence alignment enables effective detection of remote homologues. Bioinformatics (Oxford, England). 21: 2821-6. PMID 15817691 DOI: 10.1093/Bioinformatics/Bti432  0.348
2005 Pandit SB, Balaji S, Srinivasan N. Structural and functional characterization of gene products encoded in the human genome by homology detection. Iubmb Life. 56: 317-31. PMID 15370880 DOI: 10.1080/15216540400006105  0.465
2004 Shenoy AR, Sivakumar K, Krupa A, Srinivasan N, Visweswariah SS. A survey of nucleotide cyclases in actinobacteria: unique domain organization and expansion of the class III cyclase family in Mycobacterium tuberculosis. Comparative and Functional Genomics. 5: 17-38. PMID 18629044 DOI: 10.1002/Cfg.349  0.324
2004 Namboori S, Srinivasan N, Pandit SB. Recognition of remotely related structural homologues using sequence profiles of aligned homologous protein structures. In Silico Biology. 4: 445-60. PMID 15506994  0.371
2004 Namboori S, Mhatre N, Sujatha S, Srinivasan N, Pandit SB. Enhanced functional and structural domain assignments using remote similarity detection procedures for proteins encoded in the genome of Mycobacterium tuberculosis H37Rv. Journal of Biosciences. 29: 245-59. PMID 15381846 DOI: 10.1007/Bf02702607  0.496
2004 Krupa A, Preethi G, Srinivasan N. Structural modes of stabilization of permissive phosphorylation sites in protein kinases: distinct strategies in Ser/Thr and Tyr kinases. Journal of Molecular Biology. 339: 1025-1039. PMID 15178245 DOI: 10.1016/J.Jmb.2004.04.043  0.416
2004 Pandit SB, Bhadra R, Gowri VS, Balaji S, Anand B, Srinivasan N. SUPFAM: a database of sequence superfamilies of protein domains. Bmc Bioinformatics. 5: 28. PMID 15113407 DOI: 10.1186/1471-2105-5-28  0.448
2004 Singh SR, Rekha N, Pillai B, Singh V, Naorem A, Sampath V, Srinivasan N, Sadhale PP. Domainal organization of the lower eukaryotic homologs of the yeast RNA polymerase II core subunit Rpb7 reflects functional conservation Nucleic Acids Research. 32: 201-210. PMID 14704357 DOI: 10.1093/Nar/Gkh163  0.334
2004 Krupa A, Abhinandan KR, Srinivasan N. KinG: a database of protein kinases in genomes. Nucleic Acids Research. 32: D153-5. PMID 14681382 DOI: 10.1093/Nar/Gkh019  0.415
2004 Balaji S, Aruna S, Srinivasan N. Tolerance to the substitution of buried apolar residues by charged residues in the homologous protein structures. Proteins. 53: 783-91. PMID 14635121 DOI: 10.1002/Prot.10416  0.367
2004 Praseeda M, Pradeep KK, Krupa A, Krishna SS, Leena S, Kumar RR, Cheriyan J, Mayadevi M, Srinivasan N, Omkumar RV. Influence of a mutation in the ATP-binding region of Ca2+/calmodulin-dependent protein kinase II on its interaction with peptide substrates. The Biochemical Journal. 378: 391-7. PMID 14558884 DOI: 10.1042/Bj20030741  0.367
2003 Sampath V, Rekha N, Srinivasan N, Sadhale P. The Conserved and Non-conserved Regions of Rpb4 Are Involved in Multiple Phenotypes in Saccharomyces cerevisiae Journal of Biological Chemistry. 278: 51566-51576. PMID 14530281 DOI: 10.1074/Jbc.M305863200  0.352
2003 Sandhya S, Kishore S, Sowdhamini R, Srinivasan N. Effective detection of remote homologues by searching in sequence dataset of a protein domain fold. Febs Letters. 552: 225-30. PMID 14527691 DOI: 10.1016/S0014-5793(03)00929-3  0.384
2003 Pandit SB, Srinivasan N. Survey for g-proteins in the prokaryotic genomes: prediction of functional roles based on classification. Proteins. 52: 585-97. PMID 12910458 DOI: 10.1002/Prot.10420  0.448
2003 Eswar N, Ramakrishnan C, Srinivasan N. Stranded in isolation: structural role of isolated extended strands in proteins. Protein Engineering. 16: 331-339. PMID 12826724 DOI: 10.1093/Protein/Gzg046  0.347
2003 Shenoy AR, Srinivasan N, Subramaniam M, Visweswariah SS. Mutational analysis of the Mycobacterium tuberculosis Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerization. Febs Letters. 545: 253-9. PMID 12804785 DOI: 10.1016/S0014-5793(03)00580-5  0.345
2003 Rekha N, Srinivasan N. Structural basis of regulation and substrate specificity of protein kinase CK2 deduced from the modeling of protein-protein interactions. Bmc Structural Biology. 3: 4. PMID 12740046 DOI: 10.1186/1472-6807-3-4  0.416
2003 Sopory S, Balaji S, Srinivasan N, Visweswariah SS. Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5. Febs Letters. 539: 161-6. PMID 12650945 DOI: 10.1016/S0014-5793(03)00219-9  0.349
2003 Pudi R, Abhiman S, Srinivasan N, Das S. Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen. The Journal of Biological Chemistry. 278: 12231-40. PMID 12540850 DOI: 10.1074/Jbc.M210287200  0.336
2003 Gowri VS, Pandit SB, Karthik PS, Srinivasan N, Balaji S. Integration of related sequences with protein three-dimensional structural families in an updated version of PALI database. Nucleic Acids Research. 31: 486-8. PMID 12520058 DOI: 10.1093/Nar/Gkg063  0.435
2003 Krupa A, Sandhya K, Srinivasan N, Jonnalagadda S. A conserved domain in prokaryotic bifunctional FAD synthetases can potentially catalyze nucleotide transfer Trends in Biochemical Sciences. 28: 9-12. PMID 12517446 DOI: 10.1016/S0968-0004(02)00009-9  0.358
2003 Gupta S, Pandit SB, Srinivasan N, Chatterji D. Proteomics analysis of carbon-starved Mycobacterium smegmatis: induction of Dps-like protein. Protein Engineering. 15: 503-12. PMID 12082169 DOI: 10.1093/Protein/15.6.503  0.425
2002 Krupa A, Srinivasan N. The repertoire of protein kinases encoded in the draft version of the human genome: atypical variations and uncommon domain combinations Genome Biology. 3. PMID 12537555 DOI: 10.1186/Gb-2002-3-12-Research0066  0.383
2002 Eswar N, Nagarajaram H, Ramakrishnan C, Srinivasan N. Influence of Solvent Molecules on the Stereochemical Code of Glycyl Residues in Proteins Proteins. 49: 326-334. PMID 12360522 DOI: 10.1002/Prot.10226  0.348
2002 Sehrawat S, Srinivasan N, Gopinathan KP. Functional characterization and structural modelling of late gene expression factor 4 from Bombyx mori nucleopolyhedrovirus. The Biochemical Journal. 368: 159-69. PMID 12169097 DOI: 10.1042/Bj20020456  0.44
2002 Krupa A, Srinivasan N. Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases Protein Science. 11: 1580-1584. PMID 12021457 DOI: 10.1110/Ps.3560102  0.425
2002 Shenoy AR, Srinivasan N, Visweswariah SS. The ascent of nucleotide cyclases: conservation and evolution of a theme. Journal of Biosciences. 27: 85-91. PMID 11937677 DOI: 10.1007/Bf02703763  0.327
2002 Pandit SB, Gosar D, Abhiman S, Sujatha S, Dixit SS, Mhatre NS, Sowdhamini R, Srinivasan N. SUPFAM--a database of potential protein superfamily relationships derived by comparing sequence-based and structure-based families: implications for structural genomics and function annotation in genomes. Nucleic Acids Research. 30: 289-93. PMID 11752317 DOI: 10.1093/Nar/30.1.289  0.485
2001 Bhandari R, Srinivasan N, Mahaboobi M, Ghanekar Y, Suguna K, Visweswariah SS. Functional inactivation of the human guanylyl cyclase C receptor: modeling and mutation of the protein kinase-like domain. Biochemistry. 40: 9196-9206. PMID 11478887 DOI: 10.1021/Bi002595G  0.367
2001 Balaji S, Srinivasan N. Use of a database of structural alignments and phylogenetic trees in investigating the relationship between sequence and structural variability among homologous proteins Protein Engineering. 14: 219-226. PMID 11391013 DOI: 10.1093/Protein/14.4.219  0.454
2001 Sujatha S, Balaji S, Srinivasan N. PALI: A database of alignments and phylogeny of homologous protein structures Bioinformatics. 17: 375-376. PMID 11301310 DOI: 10.1093/Bioinformatics/17.4.375  0.488
2001 Balaji S, Sujatha S, Kumar SS, Srinivasan N. PALI-a database of Phylogeny and ALIgnment of homologous protein structures. Nucleic Acids Research. 29: 61-5. PMID 11125050 DOI: 10.1093/Nar/29.1.61  0.473
2000 Vijayachandra K, Guruprasad M, Bhandari R, Manjunath UH, Somesh BP, Srinivasan N, Suguna K, Visweswariah SS. Biochemical characterization of the intracellular domain of the human guanylyl cyclase C receptor provides evidence for a catalytically active homotrimer. Biochemistry. 39: 16075-83. PMID 11123935 DOI: 10.1021/Bi0013849  0.425
2000 Lindsey-Boltz LA, Chawla G, Srinivasan N, Vijayraghavan U, Garcia-Blanco MA. The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function. Rna (New York, N.Y.). 6: 1289-305. PMID 10999606 DOI: 10.1017/S1355838200000327  0.393
1999 Walker AR, Davison PA, Bolognesi-Winfield AC, James CM, Srinivasan N, Blundell TL, Esch JJ, Marks MD, Gray JC. The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein. The Plant Cell. 11: 1337-50. PMID 10402433 DOI: 10.1105/Tpc.11.7.1337  0.544
1999 Srinivasan N, Antonelli M, Jacob G, Korn I, Romero F, Jedlicki A, Dhanaraj V, Sayed MF, Blundell TL, Allende CC, Allende JE. Structural interpretation of site-directed mutagenesis and specificity of the catalytic subunit of protein kinase CK2 using comparative modelling. Protein Engineering. 12: 119-27. PMID 10195283 DOI: 10.1093/Protein/12.2.119  0.528
1999 Korn I, Gutkind S, Srinivasan N, Blundell TL, Allende CC, Allende JE. Interactions of protein kinase CK2 subunits. Molecular and Cellular Biochemistry. 191: 75-83. PMID 10094395 DOI: 10.1007/978-1-4419-8624-5_10  0.356
1998 Sowdhamini R, Burke DF, Deane C, Huang JF, Mizuguchi K, Nagarajaram HA, Overington JP, Srinivasan N, Steward RE, Blundell TL. Protein three-dimensional structural databases: domains, structurally aligned homologues and superfamilies. Acta Crystallographica. Section D, Biological Crystallography. 54: 1168-77. PMID 10089493 DOI: 10.1107/S0907444998007148  0.753
1998 Sowdhamini R, Burke DF, Huang JF, Mizuguchi K, Nagarajaram HA, Srinivasan N, Steward RE, Blundell TL. CAMPASS: a database of structurally aligned protein superfamilies. Structure (London, England : 1993). 6: 1087-94. PMID 9753697 DOI: 10.1016/S0969-2126(98)00110-5  0.489
1997 Topham CM, Srinivasan N, Blundell TL. Prediction of the stability of protein mutants based on structural environment-dependent amino acid substitution and propensity tables. Protein Engineering. 10: 7-21. PMID 9051729 DOI: 10.1093/Protein/10.1.7  0.535
1997 Robinson C, Kalsheker NA, Srinivasan N, King CM, Garrod DR, Thompson PJ, Stewart G. On the potential significance of the enzymatic activity of mite allergens to immunogenicity. Clues to structure and function revealed by molecular characterization Clinical & Experimental Allergy. 27: 10-21. DOI: 10.1111/J.1365-2222.1997.Tb00667.X  0.335
1996 Blundell TL, Srinivasan N. Symmetry, stability, and dynamics of multidomain and multicomponent protein systems Proceedings of the National Academy of Sciences of the United States of America. 93: 14243-14248. PMID 8962033 DOI: 10.1073/Pnas.93.25.14243  0.533
1996 Srinivasan N, Bax B, Blundell TL, Parker PJ. Structural aspects of the functional modules in human protein kinase- Cα deduced from comparative analyses Proteins: Structure, Function and Genetics. 26: 217-235. PMID 8916229 DOI: 10.1002/(Sici)1097-0134(199610)26:2<217::Aid-Prot11>3.0.Co;2-S  0.562
1996 Introna M, Alles V, Castellano M, Picardi G, De Gioia L, Bottazzai B, Peri G, Breviario F, Salmona M, De Gregorio L, Dragani T, Srinivasan N, Blundell T, Hamilton T, Mantovani A. Cloning of mouse ptx3, a new member of the pentraxin gene family expressed at extrahepatic sites Blood. 87: 1862-1872. DOI: 10.1182/Blood.V87.5.1862.Bloodjournal8751862  0.535
1995 Srinivasan N, Anuradha VS, Ramakrishnan C, Sowdhamini R, Balaram P. Conformational characteristics of asparaginyl residues in proteins. International Journal of Peptide and Protein Research. 44: 112-22. PMID 7982754 DOI: 10.1111/J.1399-3011.1994.Tb00565.X  0.34
1995 Srinivasan N, White HE, Emsley J, Wood SP, Pepys MB, Blundell TL. Comparative analyses of pentraxins: implications for protomer assembly and ligand binding. Structure (London, England : 1993). 2: 1017-27. PMID 7881902 DOI: 10.1016/S0969-2126(94)00105-7  0.492
1995 May AC, Johnson MS, Rufino SD, Wako H, Zhu ZY, Sowdhamini R, Srinivasan N, Rodionov MA, Blundell TL. The recognition of protein structure and function from sequence: adding value to genome data. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 344: 373-81. PMID 7800707 DOI: 10.1098/Rstb.1994.0076  0.582
1995 Sowdhamini R, Srinivasan N, Guruprasad K, Rufino S, Dhanaraj V, Wood S, Emsley J, White H, Blundell T. Protein three-dimensional structure and molecular recognition: a story of soft locks and keys Pharmaceutica Acta Helvetiae. 69: 185-192. DOI: 10.1016/0031-6865(95)00002-Q  0.558
1994 Johnson MS, Srinivasan N, Sowdhamini R, Blundell TL. Knowledge-based protein modeling. Critical Reviews in Biochemistry and Molecular Biology. 29: 1-68. PMID 8143488 DOI: 10.3109/10409239409086797  0.589
1994 Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP. Structure of pentameric human serum amyloid P component. Nature. 367: 338-45. PMID 8114934 DOI: 10.1038/367338A0  0.464
1994 Topham CM, Srinivasan N, Thorpe CJ, Overington JP, Kalsheker NA. Comparative modelling of major house dust mite allergen Der p I: structure validation using an extended environmental amino acid propensity table. Protein Engineering. 7: 869-94. PMID 7971950 DOI: 10.1093/Protein/7.7.869  0.646
1994 Zarina S, Slingsby C, Jaenicke R, Zaidi ZH, Driessen H, Srinivasan N. Three-dimensional model and quaternary structure of the human eye lens protein gamma S-crystallin based on beta- and gamma-crystallin X-ray coordinates and ultracentrifugation. Protein Science : a Publication of the Protein Society. 3: 1840-6. PMID 7849599 DOI: 10.1002/Pro.5560031023  0.357
1994 Donate LE, Srinivasan N, Sowdhamini R, Gherardi E, Blundell TL, Aparicio S. Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP). Protein Science. 3: 2378-2394. PMID 7756992 DOI: 10.1002/Pro.5560031222  0.371
1993 Srinivasan N, Blundell TL. An evaluation of the performance of an automated procedure for comparative modelling of protein tertiary structure Protein Engineering, Design and Selection. 6: 501-512. PMID 8415577 DOI: 10.1093/Protein/6.5.501  0.554
1992 Sowdhamini R, Srinivasan N, Ramakrishnan C, Balaram P. Orthogonal beta beta motifs in proteins. Journal of Molecular Biology. 223: 845-51. PMID 1538399 DOI: 10.1016/0022-2836(92)90246-G  0.346
1991 Srinivasan N, Sowdhamini R, Ramakrishnan C, Balaram P. Conformations of disulfide bridges in proteins. International Journal of Peptide and Protein Research. 36: 147-55. PMID 2272751 DOI: 10.1111/J.1399-3011.1990.Tb00958.X  0.347
1989 Sowdhamini R, Srinivasan N, Shoichet B, Santi DV, Ramakrishnan C, Balaram P. Stereochemical modeling of disulfide bridges. Criteria for introduction into proteins by site-directed mutagenesis Protein Engineering. 3: 95-103. PMID 2594728 DOI: 10.1093/Protein/3.2.95  0.387
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