☰

Robert B. Sim - Publications

Affiliations: 
University of Leicester (UK) 
Tree Info Grants Similar researchers Related pubs Distance to... Nearest Nobel PubMed Report error

238/369 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Beirag N, Varghese PM, Neto MM, Al Aiyan A, Khan HA, Qablan M, Shamji MH, Sim RB, Temperton N, Kishore U. Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein. Viruses. 15. PMID 37376569 DOI: 10.3390/v15061269  0.554
2021 Varghese PM, Mukherjee S, Al-Mohanna FA, Saleh SM, Almajhdi FN, Beirag N, Alkahtani SH, Rajkumari R, Nal Rogier B, Sim RB, Idicula-Thomas S, Madan T, Murugaiah V, Kishore U. Human Properdin Released By Infiltrating Neutrophils Can Modulate Influenza A Virus Infection. Frontiers in Immunology. 12: 747654. PMID 34956182 DOI: 10.3389/fimmu.2021.747654  0.515
2021 Murugaiah V, Varghese PM, Beirag N, De Cordova S, Sim RB, Kishore U. Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses. Viruses. 13. PMID 34063241 DOI: 10.3390/v13050824  0.577
2020 Varghese PM, Murugaiah V, Beirag N, Temperton N, Khan HA, Alrokayan SH, Al-Ahdal MN, Nal B, Al-Mohanna FA, Sim RB, Kishore U. C4b Binding Protein Acts as an Innate Immune Effector Against Influenza A Virus. Frontiers in Immunology. 11: 585361. PMID 33488586 DOI: 10.3389/fimmu.2020.585361  0.544
2020 Murugaiah V, Varghese PM, Saleh SM, Tsolaki AG, Alrokayan SH, Khan HA, Collison KS, Sim RB, Nal B, Al-Mohanna FA, Kishore U. Complement-Independent Modulation of Influenza A Virus Infection by Factor H. Frontiers in Immunology. 11: 355. PMID 32269562 DOI: 10.3389/Fimmu.2020.00355  0.579
2019 DeCordova S, Abdelgany A, Murugaiah V, Pathan AA, Nayak A, Walker T, Shastri A, Alrokayan SH, Khan HA, Singh SK, De Pennington N, Sim RB, Kishore U. Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients. Immunobiology. PMID 31519376 DOI: 10.1016/J.Imbio.2019.07.006  0.59
2019 Ali YM, Sim RB, Schwaeble W, Sshabaan MA. Enterococcus faecalis escapes complement-mediated killing via recruitment of complement factor H. The Journal of Infectious Diseases. PMID 31058287 DOI: 10.1093/Infdis/Jiz226  0.322
2018 Mehmood A, Kouser L, Kaur A, Holmskov U, Al-Ahdal MN, Sim RB, Kishore U, Tsolaki AG. Complement Dependent and Independent Interaction Between Bovine Conglutinin and BCG: Implications in Bovine Tuberculosis. Frontiers in Immunology. 9: 3159. PMID 30804949 DOI: 10.3389/Fimmu.2018.03159  0.603
2018 Al-Mozaini MA, Tsolaki AG, Abdul-Aziz M, Abozaid SM, Al-Ahdal MN, Pathan AA, Murugaiah V, Makarov EM, Kaur A, Sim RB, Kishore U, Kouser L. Human Properdin Modulates Macrophage: BCG Interaction Thrombospondin Repeats 4 and 5. Frontiers in Immunology. 9: 533. PMID 29867915 DOI: 10.3389/Fimmu.2018.00533  0.568
2018 Kouser L, Paudyal B, Kaur A, Stenbeck G, Jones LA, Abozaid SM, Stover CM, Flahaut E, Sim RB, Kishore U. Human Properdin Opsonizes Nanoparticles and Triggers a Potent Pro-inflammatory Response by Macrophages without Involving Complement Activation. Frontiers in Immunology. 9: 131. PMID 29483907 DOI: 10.3389/Fimmu.2018.00131  0.56
2017 Pondman KM, Salvador-Morales C, Paudyal B, Sim RB, Kishore U. Interactions of the innate immune system with carbon nanotubes. Nanoscale Horizons. 2: 174-186. PMID 32260639 DOI: 10.1039/c6nh00227g  0.515
2017 Ferluga J, Kouser L, Murugaiah V, Sim RB, Kishore U. Potential influences of complement factor H in autoimmune inflammatory and thrombotic disorders. Molecular Immunology. PMID 28216098 DOI: 10.1016/J.Molimm.2017.01.015  0.607
2017 Yaseen S, Demopulos G, Dudler T, Yabuki M, Wood CL, Cummings WJ, Tjoelker LW, Fujita T, Sacks S, Garred P, Andrew P, Sim RB, Lachmann PJ, Wallis R, Lynch N, et al. Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28188176 DOI: 10.1096/Fj.201601306R  0.372
2016 Pondman KM, Paudyal B, Sim RB, Kaur A, Kouser L, Tsolaki AG, Jones LA, Salvador-Morales C, Khan HA, Ten Haken B, Stenbeck G, Kishore U. Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Nanoscale. PMID 27991644 DOI: 10.1039/C6Nr08807D  0.566
2016 Sim RB, Schwaeble W, Fujita T. Complement research in the 18th-21st centuries: Progress comes with new technology. Immunobiology. PMID 27371361 DOI: 10.1016/J.Imbio.2016.06.011  0.355
2016 Pondman KM, Tsolaki AG, Paudyal B, Shamji MH, Switzer A, Pathan AA, Abozaid SM, Ten Haken B, Stenbeck G, Sim RB, Kishore U. Complement Deposition on Nanoparticles Can Modulate Immune Responses by Macrophage, B and T Cells. Journal of Biomedical Nanotechnology. 12: 197-216. PMID 27301184  0.501
2016 Abdul-Aziz M, Tsolaki AG, Kouser L, Carroll MV, Al-Ahdal MN, Sim RB, Kishore U. Complement factor H interferes with Mycobacterium bovis BCG entry into macrophages and modulates the pro-inflammatory cytokine response. Immunobiology. PMID 27262511 DOI: 10.1016/J.Imbio.2016.05.011  0.597
2016 Kouser L, Abdul-Aziz M, Tsolaki AG, Singhal D, Schwaeble WJ, Urban BC, Khan HA, Sim RB, Kishore U. A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway. Molecular Immunology. 73: 76-87. PMID 27060503 DOI: 10.1016/J.Molimm.2016.03.005  0.623
2015 Sim RB, Ferluga J, Al-Rashidi H, Abbow H, Schwaeble W, Kishore U. Complement factor H in its alternative identity as adrenomedullin-binding protein 1. Molecular Immunology. 68: 45-8. PMID 26597206 DOI: 10.1016/J.Molimm.2015.06.006  0.6
2015 Pondman KM, Pednekar L, Paudyal B, Tsolaki AG, Kouser L, Khan HA, Shamji MH, Ten Haken B, Stenbeck G, Sim RB, Kishore U. Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26169151 DOI: 10.1016/J.Nano.2015.06.009  0.586
2014 Reid KB, Bentley DR, Campbell RD, Chung LP, Sim RB, Kristensen T, Tack BF. Complement system proteins which interact with C3b or C4b A superfamily of structurally related proteins. Immunology Today. 7: 230-4. PMID 25290405 DOI: 10.1016/0167-5699(86)90110-6  0.595
2014 Ferluga J, Kishore U, Sim RB. A potential anti-coagulant role of complement factor H. Molecular Immunology. 59: 188-93. PMID 24632373 DOI: 10.1016/J.Molimm.2014.02.012  0.559
2014 Pondman KM, Sobik M, Nayak A, Tsolaki AG, Jäkel A, Flahaut E, Hampel S, Ten Haken B, Sim RB, Kishore U. Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 1287-99. PMID 24607938 DOI: 10.1016/J.Nano.2014.02.010  0.588
2014 Yu BB, Moffatt BE, Fedorova M, Villiers CG, Arnold JN, Du E, Swinkels A, Li MC, Ryan A, Sim RB. Purification, quantification, and functional analysis of Complement Factor H. Methods in Molecular Biology (Clifton, N.J.). 1100: 207-23. PMID 24218262 DOI: 10.1007/978-1-62703-724-2_17  0.393
2014 Boyajyan A, Tsakanova G, Sim R. Collectins, C3 complement protein, annexin V and C- reactive protein in acute ischemic stroke: interrelation and implication to upregulated apoptosis and inflammation Inflammation and Cell Signaling. 1. DOI: 10.14800/Ics.82  0.325
2013 Ali YM, Kenawy HI, Muhammad A, Sim RB, Andrew PW, Schwaeble WJ. Human L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae. Plos One. 8: e82583. PMID 24349316 DOI: 10.1371/Journal.Pone.0082583  0.387
2013 Bajic G, Yatime L, Sim RB, Vorup-Jensen T, Andersen GR. Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3. Proceedings of the National Academy of Sciences of the United States of America. 110: 16426-31. PMID 24065820 DOI: 10.1073/Pnas.1311261110  0.311
2013 Jakel A, Qaseem AS, Kishore U, Sim RB. Ligands and receptors of lung surfactant proteins SP-A and SP-D. Frontiers in Bioscience (Landmark Edition). 18: 1129-40. PMID 23747872 DOI: 10.2741/4168  0.555
2013 Kouser L, Abdul-Aziz M, Nayak A, Stover CM, Sim RB, Kishore U. Properdin and factor h: opposing players on the alternative complement pathway "see-saw". Frontiers in Immunology. 4: 93. PMID 23630525 DOI: 10.3389/Fimmu.2013.00093  0.574
2013 Salvador-Morales C, Khan Z, Zamory J, Tran V, Cedeno A, Umanzor-Alvarez J, Kishore U, Sim RB. Acid-Treated Multi-Walled Carbon Nanotubes Coated with Lung Surfactant Protein SP-A Do Not Induce a Lung Inflammatory Response Journal of Advanced Microscopy Research. 8: 93-99. DOI: 10.1166/Jamr.2013.1143  0.515
2013 Nayak A, Pednekar L, Waters P, Sim RB, Kishore U. Factor H interferes with C1q–Aβ interaction, and dampens classical pathway activation and subsequent neuroinflammatory response Molecular Immunology. 56: 269-269. DOI: 10.1016/J.Molimm.2013.05.088  0.515
2012 Moreno-Indias I, Dodds AW, Argüello A, Castro N, Sim RB. The complement system of the goat: haemolytic assays and isolation of major proteins. Bmc Veterinary Research. 8: 91. PMID 22734447 DOI: 10.1186/1746-6148-8-91  0.308
2012 Kang YH, Urban BC, Sim RB, Kishore U. Human complement Factor H modulates C1q-mediated phagocytosis of apoptotic cells. Immunobiology. 217: 455-64. PMID 22088229 DOI: 10.1016/J.Imbio.2011.10.008  0.58
2012 Holm L, Ackland GL, Edwards MR, Breckenridge RA, Sim RB, Offer J. Chemical labelling of active serum thioester proteins for quantification. Immunobiology. 217: 256-64. PMID 21852021 DOI: 10.1016/J.Imbio.2011.07.021  0.37
2012 Kishore U, Sim RB. Factor H as a regulator of the classical pathway activation. Immunobiology. 217: 162-8. PMID 21852018 DOI: 10.1016/J.Imbio.2011.07.024  0.603
2011 Roversi P, Johnson S, Caesar JJ, McLean F, Leath KJ, Tsiftsoglou SA, Morgan BP, Harris CL, Sim RB, Lea SM. Structures of the rat complement regulator CrrY. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 739-43. PMID 21795784 DOI: 10.1107/S1744309111016551  0.306
2011 Roversi P, Johnson S, Caesar JJ, McLean F, Leath KJ, Tsiftsoglou SA, Morgan BP, Harris CL, Sim RB, Lea SM. Structural basis for complement factor I control and its disease-associated sequence polymorphisms. Proceedings of the National Academy of Sciences of the United States of America. 108: 12839-44. PMID 21768352 DOI: 10.1073/pnas.1102167108  0.334
2011 Carroll MV, Sim RB. Complement in health and disease. Advanced Drug Delivery Reviews. 63: 965-75. PMID 21704094 DOI: 10.1016/J.Addr.2011.06.005  0.339
2011 Rybak-Smith MJ, Sim RB. Complement activation by carbon nanotubes. Advanced Drug Delivery Reviews. 63: 1031-41. PMID 21669239 DOI: 10.1016/J.Addr.2011.05.012  0.335
2011 Tan LA, Yang AC, Kishore U, Sim RB. Interactions of complement proteins C1q and factor H with lipid A and Escherichia coli: further evidence that factor H regulates the classical complement pathway. Protein & Cell. 2: 320-32. PMID 21574022 DOI: 10.1007/S13238-011-1029-Y  0.604
2011 Nilsson SC, Sim RB, Lea SM, Fremeaux-Bacchi V, Blom AM. Complement factor I in health and disease. Molecular Immunology. 48: 1611-20. PMID 21529951 DOI: 10.1016/J.Molimm.2011.04.004  0.37
2011 Díaz A, Casaravilla C, Allen JE, Sim RB, Ferreira AM. Understanding the laminated layer of larval Echinococcus II: immunology. Trends in Parasitology. 27: 264-73. PMID 21376669 DOI: 10.1016/J.Pt.2011.01.008  0.318
2011 Ilyas R, Wallis R, Soilleux EJ, Townsend P, Zehnder D, Tan BK, Sim RB, Lehnert H, Randeva HS, Mitchell DA. High glucose disrupts oligosaccharide recognition function via competitive inhibition: a potential mechanism for immune dysregulation in diabetes mellitus. Immunobiology. 216: 126-31. PMID 20674073 DOI: 10.1016/J.Imbio.2010.06.002  0.333
2010 Jäkel A, Clark H, Reid KB, Sim RB. Surface-bound myeloperoxidase is a ligand for recognition of late apoptotic neutrophils by human lung surfactant proteins A and D. Protein & Cell. 1: 563-72. PMID 21204009 DOI: 10.1007/S13238-010-0076-0  0.552
2010 Carroll MV, Sim RB, Bigi F, Jäkel A, Antrobus R, Mitchell DA. Identification of four novel DC-SIGN ligands on Mycobacterium bovis BCG. Protein & Cell. 1: 859-70. PMID 21203928 DOI: 10.1007/S13238-010-0101-3  0.349
2010 Tan LA, Yu B, Sim FC, Kishore U, Sim RB. Complement activation by phospholipids: the interplay of factor H and C1q. Protein & Cell. 1: 1033-49. PMID 21153520 DOI: 10.1007/S13238-010-0125-8  0.612
2010 Clark SJ, Perveen R, Hakobyan S, Morgan BP, Sim RB, Bishop PN, Day AJ. Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina. The Journal of Biological Chemistry. 285: 30192-202. PMID 20660596 DOI: 10.1074/Jbc.M110.103986  0.369
2010 Gulla KC, Gupta K, Krarup A, Gal P, Schwaeble WJ, Sim RB, O'Connor CD, Hajela K. Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot. Immunology. 129: 482-95. PMID 20002787 DOI: 10.1111/J.1365-2567.2009.03200.X  0.395
2010 Jäkel A, Clark H, Reid KB, Sim RB. The human lung surfactant proteins A (SP-A) and D (SP-D) interact with apoptotic target cells by different binding mechanisms. Immunobiology. 215: 551-8. PMID 19880212 DOI: 10.1016/J.Imbio.2009.09.005  0.557
2010 Nayak A, Waters P, Gadjeva M, Ferluga J, RK, Sim RB, Tsolaki A, Kishore U. Recombinant forms of monomeric and homotrimeric globular regions of human C1q as inhibitors of complement and microglia activation induced by beta-amyloid and familial dementia peptides Molecular Immunology. 47: 2284-2285. DOI: 10.1016/J.Molimm.2010.05.257  0.521
2009 Neyen C, Plüddemann A, Roversi P, Thomas B, Cai L, van der Westhuyzen DR, Sim RB, Gordon S. Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E. Biochemistry. 48: 11858-71. PMID 19911804 DOI: 10.1021/Bi9013769  0.324
2009 Kang YH, Tan LA, Carroll MV, Gentle ME, Sim RB. Target pattern recognition by complement proteins of the classical and alternative pathways. Advances in Experimental Medicine and Biology. 653: 117-28. PMID 19799115 DOI: 10.1007/978-1-4419-0901-5_8  0.336
2009 Cestari Idos S, Krarup A, Sim RB, Inal JM, Ramirez MI. Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi. Molecular Immunology. 47: 426-37. PMID 19783051 DOI: 10.1016/J.Molimm.2009.08.030  0.389
2009 Carroll MV, Lack N, Sim E, Krarup A, Sim RB. Multiple routes of complement activation by Mycobacterium bovis BCG. Molecular Immunology. 46: 3367-78. PMID 19698993 DOI: 10.1016/J.Molimm.2009.07.015  0.4
2009 Phillips AE, Toth J, Dodds AW, Girija UV, Furze CM, Pala E, Sim RB, Reid KB, Schwaeble WJ, Schmid R, Keeble AH, Wallis R. Analogous interactions in initiating complexes of the classical and lectin pathways of complement. Journal of Immunology (Baltimore, Md. : 1950). 182: 7708-17. PMID 19494295 DOI: 10.4049/Jimmunol.0900666  0.606
2009 Cole MA, Tully SE, Dodds AW, Arnold JN, Boldt GE, Sim RB, Offer J, Wentworth P. A chemical approach to immunoprotein engineering: chemoselective functionalization of thioester proteins in their native state. Chembiochem : a European Journal of Chemical Biology. 10: 1340-3. PMID 19402090 DOI: 10.1002/Cbic.200900168  0.335
2009 Schneider MC, Prosser BE, Caesar JJ, Kugelberg E, Li S, Zhang Q, Quoraishi S, Lovett JE, Deane JE, Sim RB, Roversi P, Johnson S, Tang CM, Lea SM. Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates. Nature. 458: 890-3. PMID 19225461 DOI: 10.1038/Nature07769  0.422
2009 Flores-Langarica A, Sebti Y, Mitchell DA, Sim RB, MacPherson GG. Scrapie pathogenesis: the role of complement C1q in scrapie agent uptake by conventional dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 1305-13. PMID 19155476 DOI: 10.4049/Jimmunol.182.3.1305  0.308
2009 Manukyan L, Boyajyan A, Arakelyan A, Ayvazyan V, Arakelova E, Sim R, Grigoryan G. Immunochemical composition of cryoglobulins generated in stroke. Journal of Clinical Immunology. 29: 274-81. PMID 18982431 DOI: 10.1007/S10875-008-9257-5  0.318
2008 Mahajan L, Madan T, Kamal N, Singh VK, Sim RB, Telang SD, Ramchand CN, Waters P, Kishore U, Sarma PU. Recombinant surfactant protein-D selectively increases apoptosis in eosinophils of allergic asthmatics and enhances uptake of apoptotic eosinophils by macrophages. International Immunology. 20: 993-1007. PMID 18628238 DOI: 10.1093/Intimm/Dxn058  0.539
2008 Salvador-Morales C, Basiuk EV, Basiuk VA, Green ML, Sim RB. Effects of covalent functionalization on the biocompatibility characteristics of multi-walled carbon nanotubes. Journal of Nanoscience and Nanotechnology. 8: 2347-56. PMID 18572648 DOI: 10.1166/Jnn.2008.090  0.35
2008 Mitchell DA, Ilyas R, Dodds AW, Sim RB. Enzyme-independent, orientation-selective conjugation of whole human complement C3 to protein surfaces. Journal of Immunological Methods. 337: 49-54. PMID 18572187 DOI: 10.1016/J.Jim.2008.05.011  0.389
2008 Krarup A, Mitchell DA, Sim RB. Recognition of acetylated oligosaccharides by human L-ficolin. Immunology Letters. 118: 152-6. PMID 18486240 DOI: 10.1016/J.Imlet.2008.03.014  0.313
2008 Krarup A, Gulla KC, Gál P, Hajela K, Sim RB. The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen. Biochimica Et Biophysica Acta. 1784: 1294-300. PMID 18456010 DOI: 10.1016/J.Bbapap.2008.03.020  0.417
2008 Irigoín F, Laich A, Ferreira AM, Fernández C, Sim RB, Díaz A. Resistance of the Echinococcus granulosus cyst wall to complement activation: analysis of the role of InsP6 deposits Parasite Immunology. 30: 354-364. PMID 18444958 DOI: 10.1111/J.1365-3024.2008.01034.X  0.425
2008 Boyajyan A, Khoyetsyan A, Tsakanova G, Sim RB. Cryoglobulins as indicators of upregulated immune response in schizophrenia. Clinical Biochemistry. 41: 355-60. PMID 18093542 DOI: 10.1016/J.Clinbiochem.2007.11.014  0.302
2008 Hummelshoj T, Fog LM, Madsen HO, Sim RB, Garred P. Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen). Molecular Immunology. 45: 1623-32. PMID 18006063 DOI: 10.1016/J.Molimm.2007.10.006  0.333
2008 Malhotra R, Lu J, Holmskov U, Sim RB. Collectins, collectin receptors and the lectin pathway of complement activation. Clinical and Experimental Immunology. 97: 4-9. PMID 8070142 DOI: 10.1111/J.1365-2249.1994.Tb06254.X  0.599
2007 Roumenina L, Bureeva S, Kantardjiev A, Karlinsky D, Andia-Pravdivy JE, Sim R, Kaplun A, Popov M, Kishore U, Atanasov B. Complement C1q-target proteins recognition is inhibited by electric moment effectors. Journal of Molecular Recognition : Jmr. 20: 405-15. PMID 17929239 DOI: 10.1002/Jmr.853  0.582
2007 Prosser BE, Johnson S, Roversi P, Herbert AP, Blaum BS, Tyrrell J, Jowitt TA, Clark SJ, Tarelli E, Uhrín D, Barlow PN, Sim RB, Day AJ, Lea SM. Structural basis for complement factor H linked age-related macular degeneration. The Journal of Experimental Medicine. 204: 2277-83. PMID 17893204 DOI: 10.1084/Jem.20071069  0.359
2007 Krarup A, Wallis R, Presanis JS, Gál P, Sim RB. Simultaneous activation of complement and coagulation by MBL-associated serine protease 2. Plos One. 2: e623. PMID 17637839 DOI: 10.1371/Journal.Pone.0000623  0.418
2007 Prosser BE, Johnson S, Roversi P, Clark SJ, Tarelli E, Sim RB, Day AJ, Lea SM. Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6-8. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 480-3. PMID 17554167 DOI: 10.1107/S1744309107020052  0.363
2007 Sim RB, Kishore U, Villiers CL, Marche PN, Mitchell DA. C1q binding and complement activation by prions and amyloids. Immunobiology. 212: 355-62. PMID 17544820 DOI: 10.1016/J.Imbio.2007.04.001  0.57
2007 Ghai R, Waters P, Roumenina LT, Gadjeva M, Kojouharova MS, Reid KB, Sim RB, Kishore U. C1q and its growing family. Immunobiology. 212: 253-66. PMID 17544811 DOI: 10.1016/J.Imbio.2006.11.001  0.664
2007 Schneider MC, Exley RM, Ram S, Sim RB, Tang CM. Interactions between Neisseria meningitidis and the complement system. Trends in Microbiology. 15: 233-40. PMID 17398100 DOI: 10.1016/J.Tim.2007.03.005  0.349
2007 Fernando AN, Furtado PB, Clark SJ, Gilbert HE, Day AJ, Sim RB, Perkins SJ. Associative and structural properties of the region of complement factor H encompassing the Tyr402His disease-related polymorphism and its interactions with heparin. Journal of Molecular Biology. 368: 564-81. PMID 17362990 DOI: 10.1016/J.Jmb.2007.02.038  0.341
2007 Mitchell DA, Kirby L, Paulin SM, Villiers CL, Sim RB. Prion protein activates and fixes complement directly via the classical pathway: implications for the mechanism of scrapie agent propagation in lymphoid tissue. Molecular Immunology. 44: 2997-3004. PMID 17337056 DOI: 10.1016/J.Molimm.2006.12.027  0.386
2007 Sjöberg AP, Trouw LA, Clark SJ, Sjölander J, HeinegÃ¥rd D, Sim RB, Day AJ, Blom AM. The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. The Journal of Biological Chemistry. 282: 10894-900. PMID 17293598 DOI: 10.1074/Jbc.M610256200  0.427
2007 Wallis R, Dodds AW, Mitchell DA, Sim RB, Reid KB, Schwaeble WJ. Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway. The Journal of Biological Chemistry. 282: 7844-51. PMID 17204478 DOI: 10.1074/Jbc.M606326200  0.589
2007 Radcliffe CM, Arnold JN, Suter DM, Wormald MR, Harvey DJ, Royle L, Mimura Y, Kimura Y, Sim RB, Inogès S, Rodriguez-Calvillo M, Zabalegui N, de Cerio AL, Potter KN, Mockridge CI, et al. Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor. The Journal of Biological Chemistry. 282: 7405-15. PMID 17197448 DOI: 10.1074/Jbc.M602690200  0.351
2007 Brown KS, Keogh MJ, Tagiuri N, Grainge MJ, Presanis JS, Ryder SD, Irving WL, Ball JK, Sim RB, Hickling TP. Severe fibrosis in hepatitis C virus-infected patients is associated with increased activity of the mannan-binding lectin (MBL)/MBL-associated serine protease 1 (MASP-1) complex. Clinical and Experimental Immunology. 147: 90-8. PMID 17177967 DOI: 10.1111/J.1365-2249.2006.03264.X  0.316
2007 Arnold JN, Wormald MR, Sim RB, Rudd PM, Dwek RA. The impact of glycosylation on the biological function and structure of human immunoglobulins. Annual Review of Immunology. 25: 21-50. PMID 17029568 DOI: 10.1146/Annurev.Immunol.25.022106.141702  0.313
2007 Hummelshoj T, Thielens NM, Madsen HO, Arlaud GJ, Sim RB, Garred P. Molecular organization of human Ficolin-2. Molecular Immunology. 44: 401-11. PMID 16595153 DOI: 10.1016/J.Molimm.2006.02.023  0.406
2007 Nan R, Gor J, Sim RB, Perkins SJ. Evidence for a monomer-dimer equilibrium in native human Factor H Molecular Immunology. 44: 3986. DOI: 10.1016/J.Molimm.2007.06.200  0.324
2007 Clark SJ, Collinson LJ, Sim RB, Bishop PN, Day AJ. Investigation into the glycosaminoglycan-binding properties of the AMD- and non-disease associated complement factor H variants H384 and Y384 (H402Y) Molecular Immunology. 44: 3955. DOI: 10.1016/J.Molimm.2007.06.110  0.327
2007 Roversi P, Tsiftsoglou SA, Sim RB, Lea SM. Crystallographic studies of human complement factor I Molecular Immunology. 44: 233-234. DOI: 10.1016/J.Molimm.2006.07.203  0.302
2007 Prosser BE, Roversi P, Johnson S, Clark S, Sim RB, Tarelli E, Day AJ, Lea SM. Crystallographic studies of sugar binding by factor H domains 6-8 Molecular Immunology. 44: 230-231. DOI: 10.1016/J.Molimm.2006.07.195  0.346
2007 Krarup A, Hajela K, Wallis R, Presanis JS, Gal P, Sim RB. Mannan-binding lectin associated serine protease 2 (MASP-2) activates prothrombin directly and initiates low-level clotting Molecular Immunology. 44: 198. DOI: 10.1016/J.Molimm.2006.07.120  0.332
2007 Clark SJ, Higman VA, Mulloy B, Perkins SJ, Lea S, Day AJ, Sim RB. Characterisation of the CCP7 heparin-binding site in human complement factor H: Functional variation in AMD-associated allelic variant Molecular Immunology. 44: 161-161. DOI: 10.1016/J.Molimm.2006.07.038  0.347
2007 Salvador-Morales C, Townsend P, Flahaut E, Vénien-Bryan C, Vlandas A, Green MLH, Sim RB. Binding of pulmonary surfactant proteins to carbon nanotubes; potential for damage to lung immune defense mechanisms Carbon. 45: 607-617. DOI: 10.1016/J.Carbon.2006.10.011  0.306
2006 Sim RB, Clark H, Hajela K, Mayilyan KR. Collectins and host defence. Novartis Foundation Symposium. 279: 170-186. PMID 17278394 DOI: 10.1002/9780470035399.Ch14  0.395
2006 Tsiftsoglou SA, Arnold JN, Roversi P, Crispin MD, Radcliffe C, Lea SM, Dwek RA, Rudd PM, Sim RB. Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides. Biochimica Et Biophysica Acta. 1764: 1757-66. PMID 17055788 DOI: 10.1016/J.Bbapap.2006.09.007  0.324
2006 Mayilyan KR, Arnold JN, Presanis JS, Soghoyan AF, Sim RB. Increased complement classical and mannan-binding lectin pathway activities in schizophrenia. Neuroscience Letters. 404: 336-41. PMID 16860475 DOI: 10.1016/J.Neulet.2006.06.051  0.329
2006 Arnold JN, Dwek RA, Rudd PM, Sim RB. Mannan binding lectin and its interaction with immunoglobulins in health and in disease. Immunology Letters. 106: 103-10. PMID 16814399 DOI: 10.1016/J.Imlet.2006.05.007  0.404
2006 Clark SJ, Higman VA, Mulloy B, Perkins SJ, Lea SM, Sim RB, Day AJ. His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form. The Journal of Biological Chemistry. 281: 24713-20. PMID 16787919 DOI: 10.1074/Jbc.M605083200  0.386
2006 Schneider MC, Exley RM, Chan H, Feavers I, Kang YH, Sim RB, Tang CM. Functional significance of factor H binding to Neisseria meningitidis. Journal of Immunology (Baltimore, Md. : 1950). 176: 7566-75. PMID 16751403 DOI: 10.4049/Jimmunol.176.12.7566  0.416
2006 Lillegard JB, Sim RB, Thorkildson P, Gates MA, Kozel TR. Recognition of Candida albicans by mannan-binding lectin in vitro and in vivo. The Journal of Infectious Diseases. 193: 1589-97. PMID 16652289 DOI: 10.1086/503804  0.373
2006 Martinez-Pomares L, Wienke D, Stillion R, McKenzie EJ, Arnold JN, Harris J, McGreal E, Sim RB, Isacke CM, Gordon S. Carbohydrate-independent recognition of collagens by the macrophage mannose receptor. European Journal of Immunology. 36: 1074-82. PMID 16619293 DOI: 10.1002/Eji.200535685  0.355
2006 Boskovic J, Arnold JN, Stilion R, Gordon S, Sim RB, Rivera-Calzada A, Wienke D, Isacke CM, Martinez-Pomares L, Llorca O. Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor. The Journal of Biological Chemistry. 281: 8780-7. PMID 16452473 DOI: 10.1074/Jbc.M513277200  0.323
2006 Arnold JN, Wallis R, Willis AC, Harvey DJ, Royle L, Dwek RA, Rudd PM, Sim RB. Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family? The Journal of Biological Chemistry. 281: 6955-63. PMID 16407218 DOI: 10.1074/Jbc.M511432200  0.399
2006 Salvador-Morales C, Flahaut E, Sim E, Sloan J, Green ML, Sim RB. Complement activation and protein adsorption by carbon nanotubes. Molecular Immunology. 43: 193-201. PMID 16199256 DOI: 10.1016/J.Molimm.2005.02.006  0.321
2006 Mayilyan KR, Presanis JS, Arnold JN, Hajela K, Sim RB. Heterogeneity of MBL-MASP complexes. Molecular Immunology. 43: 1286-92. PMID 16102832 DOI: 10.1016/J.Molimm.2005.07.011  0.311
2005 Rooijakkers SH, Ruyken M, Roos A, Daha MR, Presanis JS, Sim RB, van Wamel WJ, van Kessel KP, van Strijp JA. Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases. Nature Immunology. 6: 920-7. PMID 16086019 DOI: 10.1038/Ni1235  0.41
2005 Gál P, Harmat V, Kocsis A, Bián T, Barna L, Ambrus G, Végh B, Balczer J, Sim RB, Náray-Szabó G, Závodszky P. A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations. The Journal of Biological Chemistry. 280: 33435-44. PMID 16040602 DOI: 10.1074/Jbc.M506051200  0.366
2005 Arnold JN, Wormald MR, Suter DM, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, Sim RB. Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin. The Journal of Biological Chemistry. 280: 29080-7. PMID 15955802 DOI: 10.1074/Jbc.M504528200  0.375
2005 Tsiftsoglou SA, Willis AC, Li P, Chen X, Mitchell DA, Rao Z, Sim RB. The catalytically active serine protease domain of human complement factor I. Biochemistry. 44: 6239-49. PMID 15835912 DOI: 10.1021/Bi047680T  0.359
2005 Seelen MA, Roos A, Wieslander J, Mollnes TE, Sjöholm AG, Wurzner R, Loos M, Tedesco F, Sim RB, Garred P, Alexopoulos E, Turner MW, Daha MR. Functional analysis of the classical, alternative, and MBL pathways of the complement system: Standardization and validation of a simple ELISA Journal of Immunological Methods. 296: 187-198. PMID 15680163 DOI: 10.1016/J.Jim.2004.11.016  0.302
2005 Hakobyan S, Boyajyan A, Sim RB. Classical pathway complement activity in schizophrenia. Neuroscience Letters. 374: 35-7. PMID 15631892 DOI: 10.1016/J.Neulet.2004.10.024  0.319
2005 Lawrie CH, Sim RB, Nuttall PA. Investigation of the mechanisms of anti-complement activity in Ixodes ricinus ticks. Molecular Immunology. 42: 31-8. PMID 15488941 DOI: 10.1016/J.Molimm.2004.07.001  0.379
2004 Arnold JN, Radcliffe CM, Wormald MR, Royle L, Harvey DJ, Crispin M, Dwek RA, Sim RB, Rudd PM. The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin. Journal of Immunology (Baltimore, Md. : 1950). 173: 6831-40. PMID 15557177 DOI: 10.4049/Jimmunol.173.11.6831  0.404
2004 Kishore U, Gaboriaud C, Waters P, Shrive AK, Greenhough TJ, Reid KB, Sim RB, Arlaud GJ. C1q and tumor necrosis factor superfamily: modularity and versatility. Trends in Immunology. 25: 551-61. PMID 15364058 DOI: 10.1016/J.It.2004.08.006  0.676
2004 Tsiftsoglou SA, Sim RB. Human complement factor I does not require cofactors for cleavage of synthetic substrates. Journal of Immunology (Baltimore, Md. : 1950). 173: 367-75. PMID 15210795 DOI: 10.4049/Jimmunol.173.1.367  0.387
2004 Crispin MD, Ritchie GE, Critchley AJ, Morgan BP, Wilson IA, Dwek RA, Sim RB, Rudd PM. Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure. Febs Letters. 566: 270-4. PMID 15147907 DOI: 10.1016/J.Febslet.2004.04.045  0.377
2004 Kojouharova MS, Gadjeva MG, Tsacheva IG, Zlatarova A, Roumenina LT, Tchorbadjieva MI, Atanasov BP, Waters P, Urban BC, Sim RB, Reid KB, Kishore U. Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction. Journal of Immunology (Baltimore, Md. : 1950). 172: 4351-8. PMID 15034050 DOI: 10.4049/Jimmunol.172.7.4351  0.692
2004 Ferreira V, Valck C, Sánchez G, Gingras A, Tzima S, Molina MC, Sim R, Schwaeble W, Ferreira A. The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi. Journal of Immunology (Baltimore, Md. : 1950). 172: 3042-50. PMID 14978109 DOI: 10.4049/Jimmunol.172.5.3042  0.388
2004 Larsen F, Madsen HO, Sim RB, Koch C, Garred P. Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. Journal of Biological Chemistry. 279: 21302-21311. PMID 14764589 DOI: 10.1074/Jbc.M400520200  0.331
2004 Sim RB, Tsiftsoglou SA. Proteases of the complement system Biochemical Society Transactions. 32: 21-27. PMID 14748705 DOI: 10.1042/Bst0320021  0.439
2004 Presanis JS, Hajela K, Ambrus G, Gál P, Sim RB. Differential substrate and inhibitor profiles for human MASP-1 and MASP-2. Molecular Immunology. 40: 921-929. PMID 14725788 DOI: 10.1016/J.Molimm.2003.10.013  0.378
2004 Hickling TP, Clark HW, Malhotra R, Sim RB. Collectins and their role in lung immunity. Journal of Leukocyte Biology. 75: 27-33. PMID 12972515 DOI: 10.1189/Jlb.0703304  0.358
2003 Presanis JS, Kojima M, Sim RB. Biochemistry and genetics of mannan-binding lectin (MBL). Biochemical Society Transactions. 31: 748-752. PMID 12887296 DOI: 10.1042/Bst0310748  0.424
2003 Ambrus G, Gál P, Kojima M, Szilágyi K, Balczer J, Antal J, Gráf L, Laich A, Moffatt BE, Schwaeble W, Sim RB, Závodszky P. Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments. Journal of Immunology (Baltimore, Md. : 1950). 170: 1374-82. PMID 12538697 DOI: 10.4049/Jimmunol.170.3.1374  0.376
2002 Kojima M, Presanis JS, Sim RB. The mannose-binding lectin (MBL) route for activation of complement Advances in Experimental Medicine and Biology. 535: 229-250. PMID 14714899 DOI: 10.1007/978-1-4615-0065-0_15  0.426
2002 Dumestre-Perard C, Ponard D, Arlaud GJ, Monnier N, Sim RB, Colomb MG. Evaluation and clinical interest of mannan binding lectin function in human plasma. Molecular Immunology. 39: 465-473. PMID 12413698 DOI: 10.1016/S0161-5890(02)00119-0  0.397
2002 Hajela K, Kojima M, Ambrus G, Wong KH, Moffatt BE, Ferluga J, Hajela S, Gál P, Sim RB. The biological functions of MBL-associated serine proteases (MASPs). Immunobiology. 205: 467-75. PMID 12396008 DOI: 10.1078/0171-2985-00147  0.394
2002 Lynch NJ, Schneider H, Sim RB, Bickel U, Schwaeble WJ. In vivo pharmacokinetics of calreticulin S-domain, an inhibitor of the classical complement pathway International Immunopharmacology. 2: 415-422. PMID 11962721 DOI: 10.1016/S1567-5769(01)00165-5  0.328
2002 Ritchie GE, Moffatt BE, Sim RB, Morgan BP, Dwek RA, Rudd PM. Glycosylation and the complement system. Chemical Reviews. 102: 305-20-19. PMID 11841245 DOI: 10.1021/Cr990294A  0.319
2002 Chen XH, Tsiftsoglou SA, Li PY, Mitchell DA, Salamanca S, Rao Z, Sim RB. Activity studies on human complement factor I (FI) Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A118B  0.326
2002 Tan LA, Kishore U, Sim RB. Characterization of complement protein C1q binding to U937 myelomonocytic cells Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A118  0.58
2001 Ferreira AM, Diaz A, Fernandez C, Sim RB. Assessment of in vivo complement activation on the Echinococcus granulosus hydatid cyst wall Parasite Immunology. 23: 655-658. PMID 11737668 DOI: 10.1046/J.1365-3024.2001.00424.X  0.34
2001 Laich A, Sim RB. Complement C4bC2 complex formation: An investigation by surface plasmon resonance Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1544: 96-112. PMID 11341920 DOI: 10.1016/S0167-4838(00)00208-9  0.345
2000 Sim RB, Laich A. Serine proteases of the complement system Biochemical Society Transactions. 28: 545-550. PMID 11044372 DOI: 10.1042/Bst0280545  0.44
2000 Dı́az A, Ibarguren S, Breijo M, Willis AC, Sim RB. Host-derived annexin II at the host-parasite interface of the Echinococcus granulosus hydatid cyst. Molecular and Biochemical Parasitology. 110: 171-176. PMID 10989155 DOI: 10.1016/S0166-6851(00)00256-5  0.307
2000 Ferreira AM, Breijo M, Sim RB, Nieto A. Contribution of C5‐mediated mechanisms to host defence against Echinococcus granulosus hydatid infection Parasite Immunology. 22: 445-453. PMID 10972851 DOI: 10.1046/J.1365-3024.2000.00323.X  0.317
2000 Vorup-Jensen T, Petersen SV, Hansen AG, Poulsen K, Schwaeble W, Sim RB, Reid KB, Davis SJ, Thiel S, Jensenius JC. Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2. Journal of Immunology (Baltimore, Md. : 1950). 165: 2093-100. PMID 10925294 DOI: 10.4049/Jimmunol.165.4.2093  0.596
2000 Schäfer MK, Schwaeble WJ, Post C, Salvati P, Calabresi M, Sim RB, Petry F, Loos M, Weihe E. Complement C1q is dramatically up-regulated in brain microglia in response to transient global cerebral ischemia. Journal of Immunology (Baltimore, Md. : 1950). 164: 5446-52. PMID 10799911 DOI: 10.4049/Jimmunol.164.10.5446  0.307
2000 Inal JM, Sim RB. A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2 Febs Letters. 470: 131-134. PMID 10734221 DOI: 10.1016/S0014-5793(00)01304-1  0.432
2000 Hickling TP, Malhotra R, Bright H, Mcdowell W, Blair ED, Sim RB. Lung surfactant protein A provides a route of entry for respiratory syncytial virus into host cells. Viral Immunology. 13: 125-135. PMID 10733174 DOI: 10.1089/Vim.2000.13.125  0.312
2000 Ferreira AM, Irigoı́n F, Breijo M, Sim RB, Dı́az A. How Echinococcus granulosus Deals with Complement Parasitology Today. 16: 168-172. PMID 10725905 DOI: 10.1016/S0169-4758(99)01625-7  0.32
2000 Laich A, Moffatt B, Wong KHN, Hickling TP, Koch C, Sim RB. Purification of The Second Component of Human Complement, C2, by Antibody Affinity Chromatography Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A490B  0.338
1999 Wong NKH, Kojima M, Dobó J, Ambrus G, Sim RB. Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors. Molecular Immunology. 36: 853-861. PMID 10698339 DOI: 10.1016/S0161-5890(99)00106-6  0.351
1999 Hickling TP, Bright H, Wing K, Gower D, Martin SL, Sim RB, Malhotra R. A recombinant trimeric surfactant protein D carbohydrate recognition domain inhibits respiratory syncytial virus infection in vitro and in vivo. European Journal of Immunology. 29: 3478-84. PMID 10556802 DOI: 10.1002/(Sici)1521-4141(199911)29:11<3478::Aid-Immu3478>3.0.Co;2-W  0.332
1999 Dı́az A, Irigoı́n F, Ferreira F, Sim RB. Control of host complement activation by the Echinococcus granulosus hydatid cyst. Immunopharmacology. 42: 91-98. PMID 10408370 DOI: 10.1016/S0162-3109(99)00023-5  0.338
1999 Williams SC, Hinshelwood J, Perkins SJ, Sim RB. Production and functional activity of a recombinant von Willebrand factor-A domain from human complement factor B. Biochemical Journal. 342: 625-632. DOI: 10.1042/Bj3420625  0.358
1999 Malhotra R, Ward M, Sim RB, Bird MI. Identification of human complement Factor H as a ligand for L-selectin. Biochemical Journal. 341: 61-69. DOI: 10.1042/Bj3410061  0.353
1998 Ullman CG, Chamberlain D, Ansari A, Emery VC, Haris PI, Sim RB, Perkins SJ. Human complement factor I: Its expression by insect cells and its biochemical and structural characterisation Molecular Immunology. 35: 503-512. PMID 9809578 DOI: 10.1016/S0161-5890(98)00052-2  0.368
1998 Hickling TP, Sim RB, Malhotra R. Induction of TNF-α release from human buffy coat cells by Pseudomonas aeruginosa is reduced by lung surfactant protein A Febs Letters. 437: 65-69. PMID 9804173 DOI: 10.1016/S0014-5793(98)01200-9  0.305
1998 Sim RB, Moestrup SK, Stuart GR, Lynch NJ, Lu J, Schwaeble WJ, Malhotra R. Interaction of C1q and the Collectins with the Potential Receptors Calreticulin (cClqR/Collectin Receptor) and Megalin Immunobiology. 199: 208-224. PMID 9777407 DOI: 10.1016/S0171-2985(98)80028-4  0.559
1998 Vorup-Jensen T, Davis S, Poulsen K, Schwaeble W, Stover C, Sim R, Reid K, Petersen S, Thiel S, Jensenius J. Studies of recombinant MBL and MASP-2: Is MASP-2 self-activating? Molecular Immunology. 35: 409. DOI: 10.1016/S0161-5890(98)90847-1  0.421
1998 Malhotra R, Ward M, Sim RB, Lipscombe RJ, Bird MI. Human complement factor H is an L-selectin ligand Molecular Immunology. 35: 376. DOI: 10.1016/S0161-5890(98)90713-1  0.302
1998 Ferluga J, Yu B-, Guerin J, Jackson J, Sim RB. Similarities between complement factor H and β2 glycoprotein 1: Phospholipid binding and autoantibodies Molecular Immunology. 35: 375. DOI: 10.1016/S0161-5890(98)90711-8  0.339
1998 Hickling TP, Malhotra R, Sim RB. Human lung surfactant protein A exists in several different oligomeric states: oligomer size distribution varies between patient groups. Molecular Medicine. 4: 266-275. DOI: 10.1007/Bf03401923  0.352
1998 He S, Sim RB, Whaley K. Mechanism of Action of Anti-C1-Inhibitor Autoantibodies: Prevention of the Formation of Stable C1s-C1-inh Complexes Molecular Medicine. 4: 119-128. DOI: 10.1007/Bf03401735  0.304
1997 Stuart GR, Lynch NJ, Day AJ, Schwaeble WJ, Sim RB. The C1q and collectin binding site within C1q receptor (cell surface calreticulin). Immunopharmacology. 38: 73-80. PMID 9476117 DOI: 10.1016/S0162-3109(97)00076-3  0.365
1997 Soames CJ, Sim RB. Interactions between human complement components factor H, factor I and C3b Biochemical Journal. 326: 553-561. PMID 9291131 DOI: 10.1042/Bj3260553  0.39
1997 He S, Yang J-, Tsang S, Sim RB, Whaley K. Role of the distal hinge region of C1-inhibitor in the regulation of C1s activity Febs Letters. 412: 506-510. PMID 9276455 DOI: 10.1016/S0014-5793(97)00803-X  0.33
1997 He S, Sim RB, Whaley K. A secondary C1s interaction site on C1-inhibitor is essential for formation of a stable enzyme-inhibitor complex Febs Letters. 405: 42-46. PMID 9094421 DOI: 10.1016/S0014-5793(96)01529-3  0.344
1997 Wallace EM, Perkins SJ, Sim RB, Willis AC, Feighery C, Jackson J. Degradation of C1-Inhibitor by Plasmin: Implications for the Control of Inflammatory Processes Molecular Medicine. 3: 385-396. DOI: 10.1007/Bf03401685  0.321
1996 Irigoín F, Würzner R, Sim RB, Ferreira AM. Comparison of complement activation in vitro by different Echinococcus granulosus extracts. Parasite Immunology. 18: 371-375. PMID 9229390 DOI: 10.1046/J.1365-3024.1996.D01-112.X  0.348
1996 Stuart GR, Lynch NJ, Lu J, Geick A, Moffatt BE, Sim RB, Schwaeble WJ. Localisation of the C1q binding site within C1q receptor/calreticulin. Febs Letters. 397: 245-9. PMID 8955356 DOI: 10.1016/S0014-5793(96)01156-8  0.582
1996 Stuart GR, Sim RB, Malhotra R. Characterization of radioiodinated lung surfactant protein A (SP-A) and the effects of oxidation of SP-A quaternary structure and activity Experimental Lung Research. 22: 467-487. PMID 8872089 DOI: 10.3109/01902149609046036  0.328
1996 Fijen CA, Kuijper EJ, Te Bulte M, van de Heuvel MM, Holdrinet AC, Sim RB, Daha MR, Dankert J. Heterozygous and homozygous factor H deficiency states in a Dutch family. Clinical and Experimental Immunology. 105: 511-6. PMID 8809142 DOI: 10.1046/J.1365-2249.1996.D01-777.X  0.37
1996 Moestrup SK, Birn H, Fischer PB, Petersen CM, Verroust PJ, Sim RB, Christensen EI, Nexo E. Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 93: 8612-8617. PMID 8710919 DOI: 10.1073/Pnas.93.16.8612  0.31
1996 Soames CJ, Day AJ, Sim RB. Prediction from sequence comparisons of residues of factor H involved in the interaction with complement component C3b Biochemical Journal. 315: 523-531. PMID 8615824 DOI: 10.1042/Bj3150523  0.386
1995 Soames CJ, Sim RB. An investigation of the interaction between human complement factor H and C3b Biochemical Society Transactions. 23. PMID 7758768 DOI: 10.1042/Bst023053S  0.424
1995 Ullman CG, Haris PI, Smith KF, Sim RB, Emery VC, Perkins SJ. β-Sheet secondary structure of an LDL receptor domain from complement factor I by consensus structure predictions and spectroscopy Febs Letters. 371: 199-203. PMID 7672128 DOI: 10.1016/0014-5793(95)00916-W  0.306
1995 Kertesz Z, Yu B, Steinkasserer A, Haupt H, Benham A, Sim RB. Characterization of binding of human beta 2-glycoprotein I to cardiolipin. Biochemical Journal. 310: 315-321. PMID 7646462 DOI: 10.1042/Bj3100315  0.314
1995 Schelenz S, Malhotra R, Sim RB, Holmskov U, Bancroft GJ. Binding of host collectins to the pathogenic yeast Cryptococcus neoformans: human surfactant protein D acts as an agglutinin for acapsular yeast cells. Infection and Immunity. 63: 3360-6. PMID 7642263 DOI: 10.1128/Iai.63.9.3360-3366.1995  0.41
1995 Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB. Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nature Medicine. 1: 237-43. PMID 7585040 DOI: 10.1038/Nm0395-237  0.353
1994 Williams SC, Sim RB. Binding sites involved in the formation of the C3(H2O)-factor B complex of the alternative pathway of complement Biochemical Society Transactions. 22. PMID 8206227 DOI: 10.1042/Bst022002S  0.429
1994 Holmskov U, Malhotra R, Sim RB, Jensenius JC. Collectins: collagenous C-type lectins of the innate immune defense system Immunology Today. 15: 67-74. PMID 8155265 DOI: 10.1016/0167-5699(94)90136-8  0.409
1994 Perkins SJ, Smith KF, Williams SC, Haris PI, Chapman D, Sim RB. The secondary structure of the von Willebrand factor type A domain in factor B of human complement by Fourier transform infrared spectroscopy. Its occurrence in collagen types VI, VII, XII and XIV, the integrins and other proteins by averaged structure predictions. Journal of Molecular Biology. 238: 104-119. PMID 8145250 DOI: 10.1006/Jmbi.1994.1271  0.31
1994 Malhotra R, Haurum JS, Thiel S, Sim RB. Binding of human collectins (SP-A and MBP) to influenza virus. Biochemical Journal. 304: 455-461. PMID 7998980 DOI: 10.1042/Bj3040455  0.338
1993 Bakács T, Végh Z, Merry AH, Sim RB, Varga L, Kertész Z, Tusnády G, Klein E. Interactions in the complement-mediated lysis of blood group AB erythrocytes sensitized simultaneously with anti-A and anti-B monoclonal antibodies. Immunology Letters. 35: 219-228. PMID 8514333 DOI: 10.1016/0165-2478(93)90186-6  0.323
1993 Peerschke EI, Malhotra R, Ghebrehiwet B, Reid KB, Willis AC, Sim RB. Isolation of a human endothelial cell C1q receptor (C1qR). Journal of Leukocyte Biology. 53: 179-84. PMID 8445329 DOI: 10.1002/Jlb.53.2.179  0.55
1993 Williams SC, Sim RB. Dye-ligand affinity purification of human complement factor B and β2 glycoprotein I Journal of Immunological Methods. 157: 25-30. PMID 8423369 DOI: 10.1016/0022-1759(93)90066-G  0.331
1993 Malhotra R, Haurum J, Thiel S, Jensenius JC, Sim RB. Pollen grains bind to lung alveolar type II cells (A549) via lung surfactant protein A (SP-A) Bioscience Reports. 13: 79-90. PMID 8374060 DOI: 10.1007/Bf01145960  0.342
1993 Barlow PN, Steinkasserer A, Norman DG, Kieffer B, Wiles AP, Sim RB, Campbell ID. Solution structure of a pair of complement modules by nuclear magnetic resonance. Journal of Molecular Biology. 232: 268-84. PMID 8331663 DOI: 10.1006/Jmbi.1993.1381  0.313
1993 Malhotra R, Laursen SB, Willis AC, Sim RB. Localization of the receptor-binding site in the collectin family of proteins Biochemical Journal. 293: 15-19. PMID 8328957 DOI: 10.1042/Bj2930015  0.359
1993 Lu J, Willis AC, Sim RB. A calreticulin-like protein co-purifies with a '60 kD' component of Ro/SSA, but is not recognized by antibodies in Sjogren's syndrome sera Clinical and Experimental Immunology. 94: 429-434. PMID 8252803 DOI: 10.1111/J.1365-2249.1993.Tb08213.X  0.564
1993 Perkins SJ, Smith KF, Sim RB. Molecular modelling of the domain structure of factor I of human complement by X-ray and neutron solution scattering. Biochemical Journal. 295: 101-108. PMID 8216202 DOI: 10.1042/Bj2950101  0.314
1993 Kunnath-Muglia LM, Chang GH, Sim RB, Day AJ, Ezekowitz RA. Characterization of Xenopus laevis complement factor I structure--conservation of modular structure except for an unusual insert not present in human factor I. Molecular Immunology. 30: 1249-56. PMID 7692240 DOI: 10.1016/0161-5890(93)90040-I  0.329
1992 Malhotra R, Haurum J, Thiel S, Sim RB. Interaction of C1q receptor with lung surfactant protein A. European Journal of Immunology. 22: 1437-1445. PMID 1601034 DOI: 10.1002/Eji.1830220616  0.351
1992 Barlow PN, Norman DG, Steinkasserer A, Horne TJ, Pearce J, Driscoll PC, Sim RB, Campbell ID. Solution structure of the fifth repeat of factor H: a second example of the complement control protein module. Biochemistry. 31: 3626-34. PMID 1533152 DOI: 10.1021/Bi00129A011  0.316
1992 Julen N, Dauchel H, Lemercier C, Sim RB, Fontaine M, Ripoche J. In vitro biosynthesis of complement factor I by human endothelial cells. European Journal of Immunology. 22: 213-217. PMID 1530917 DOI: 10.1002/Eji.1830220131  0.356
1992 Steinkasserer A, Barlow PN, Willis AC, Kertesz Z, Campbell ID, Sim RB, Norman DG. Activity, disulphide mapping and structural modelling of the fifth domain of human beta 2-glycoprotein I. Febs Letters. 313: 193-7. PMID 1426288 DOI: 10.1016/0014-5793(92)81442-O  0.305
1991 Norman DG, Barlow PN, Baron M, Day AJ, Sim RB, Campbell ID. Three-dimensional structure of a complement control protein module in solution. Journal of Molecular Biology. 219: 717-25. PMID 1829116 DOI: 10.1016/0022-2836(91)90666-T  0.3
1991 Perkins SJ, Nealis AS, Sim RB. Oligomeric domain structure of human complement factor H by X-ray and neutron solution scattering. Biochemistry. 30: 2847-2857. PMID 1826087 DOI: 10.1021/Bi00225A017  0.34
1991 Barlow PN, Baron M, Norman DG, Day AJ, Willis AC, Sim RB, Campbell ID. Secondary structure of a complement control protein module by two-dimensional 1H NMR. Biochemistry. 30: 997-1004. PMID 1824927 DOI: 10.1021/Bi00218A016  0.325
1991 Sim RB, Reid KBM. C1: Molecular interactions with activating systems Immunology Today. 12: 307-311. PMID 1755942 DOI: 10.1016/0167-5699(91)90004-D  0.337
1990 Sim RB, Perkins SJ. Molecular modelling of C3 and its ligands Current Topics in Microbiology and Immunology. 153: 209-222. PMID 2404695 DOI: 10.1007/978-3-642-74977-3_11  0.324
1990 Malhotra R, Thiel S, Reid KB, Sim RB. Human leukocyte C1q receptor binds other soluble proteins with collagen domains. The Journal of Experimental Medicine. 172: 955-9. PMID 2388038 DOI: 10.1084/Jem.172.3.955  0.571
1990 MALHOTRA R, SIM RB, REID KBM. Interaction of C1q, and other proteins containing collagen-like domains, with the C1q receptor Biochemical Society Transactions. 18: 1145-1148. DOI: 10.1042/Bst0181145  0.324
1989 Malhotra R, Sim RB. Chemical and hydrodynamic characterization of the human leucocyte receptor for complement subcomponent C1q Biochemical Journal. 262: 625-631. PMID 2803272 DOI: 10.1042/Bj2620625  0.321
1989 Jackson J, Sim RB, Whaley K, Feighery C. Autoantibody facilitated cleavage of C1-inhibitor in autoimmune angioedema. Journal of Clinical Investigation. 83: 698-707. PMID 2536404 DOI: 10.1172/Jci113934  0.342
1989 Fontaine M, Demares MJ, Koistinen V, Day AJ, Davrinche C, Sim RB, Ripoche J. Truncated forms of human complement factor H. Biochemical Journal. 258: 927-930. PMID 2525027 DOI: 10.1042/Bj2580927  0.315
1989 Merry AH, Rawlinson VI, Uchikawa M, Daha MR, Sim RB. Studies on the sensitivity to complement-mediated lysis of erythrocytes (Inab phenotype) with a deficiency of DAF (decay accelerating factor). British Journal of Haematology. 73: 248-53. PMID 2479410 DOI: 10.1111/J.1365-2141.1989.Tb00260.X  0.323
1988 Cooper GJ, Willis AC, Clark A, Turner RC, Sim RB, Reid KB. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proceedings of the National Academy of Sciences of the United States of America. 84: 8628-32. PMID 3317417 DOI: 10.1073/Pnas.84.23.8628  0.485
1988 Hing S, Day AJ, Linton SJ, Ripoche J, Sim RB, Reid KBM, Solomon E. Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes Annals of Human Genetics. 52: 117-122. PMID 2977721 DOI: 10.1111/J.1469-1809.1988.Tb01086.X  0.357
1988 Ripoche J, Mitchell JA, Erdei A, Madin C, Moffatt B, Mokoena T, Gordon S, Sim RB. Interferon gamma induces synthesis of complement alternative pathway proteins by human endothelial cells in culture. The Journal of Experimental Medicine. 168: 1917-22. PMID 2972796 DOI: 10.1084/Jem.168.5.1917  0.351
1988 Ripoche J, Erdei A, Gilbert D, Salihi AA, Sim RB, Fontaine M. Two populations of complement factor H differ in their ability to bind to cell surfaces Biochemical Journal. 253: 475-480. PMID 2972274 DOI: 10.1042/Bj2530475  0.377
1988 Ripoche J, Day AJ, Harris TJR, Sim RB. The complete amino acid sequence of human complement factor H. Biochemical Journal. 249: 593-602. PMID 2963625 DOI: 10.1042/Bj2490593  0.319
1988 Day AJ, Willis AC, Ripoche J, Sim RB. Sequence polymorphism of human complement factor H Immunogenetics. 27: 211-214. PMID 2962936 DOI: 10.1007/Bf00346588  0.327
1988 Campbell RD, Law SKA, Reid KBM, Sim RB. Structure, Organization , And Regulation Of The Complement Genes Annual Review of Immunology. 6: 161-195. PMID 2898251 DOI: 10.1146/Annurev.Iy.06.040188.001113  0.404
1987 Sim RB, Malhotra V, Day AJ, Erdei A. Structure and specificity of complement receptors Immunology Letters. 14: 183-190. PMID 3552967 DOI: 10.1016/0165-2478(87)90099-X  0.399
1987 Adams SE, Mellor J, Gull K, Sim RB, Tuite MF, Kingsman SM, Kingsman AJ. The functions and relationships of Ty-VLP proteins in yeast reflect those of mammalian retroviral proteins. Cell. 49: 111-119. PMID 3030564 DOI: 10.1016/0092-8674(87)90761-6  0.301
1987 Erdei A, Sim RB. Complement factor H-binding protein of Raji cells and tonsil B lymphocytes Biochemical Journal. 246: 149-156. PMID 2960319 DOI: 10.1042/Bj2460149  0.369
1987 Catterall CF, Lyons A, Sim RB, Day AJ, Harris TJR. Characterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones. Biochemical Journal. 242: 849-856. PMID 2954545 DOI: 10.1042/Bj2420849  0.326
1987 Day AJ, Ripoche J, Lyons A, McIntosh B, Harris TJR, Sim RB. Sequence analysis of a cDNA clone encoding the C-terminal end of human complement factor H Bioscience Reports. 7: 201-207. PMID 2889480 DOI: 10.1007/Bf01124790  0.323
1986 Malhotra V, Hogg N, Sim RB. Ligand binding by the p150,95 antigen of U937 monocytic cells: Properties in common with complement receptor type 3 (CR3) European Journal of Immunology. 16: 1117-1123. PMID 3530784 DOI: 10.1002/Eji.1830160915  0.339
1986 Ripoche J, Day AJ, Willis AC, Belt KT, Campbell RD, Sim RB. Partial characterization of human complement factor H by protein and cDNA sequencing: homology with other complement and non-complement proteins. Bioscience Reports. 6: 65-72. PMID 2938641 DOI: 10.1007/Bf01145180  0.395
1986 Folkersen J, Teisner B, Eggertsen G, Sim RB. Immunoblotting analysis of the peptide chain structure of the physiological breakdown products of the third component of human complement Electrophoresis. 7: 379-386. DOI: 10.1002/Elps.1150070807  0.361
1985 Micklem KJ, Sim RB. Isolation of complement-fragment-iC3b-binding proteins by affinity chromatography. The identification of p150,95 as an iC3b-binding protein Biochemical Journal. 231: 233-236. PMID 4062888 DOI: 10.1042/Bj2310233  0.355
1985 Blackwell JM, Ezekowitz RAB, Roberts MB, Channon JY, Sim RB, Gordon S. Macrophage complement and lectin-like receptors bind Leishmania in the absence of serum. Journal of Experimental Medicine. 162: 324-331. PMID 3891904 DOI: 10.1084/Jem.162.1.324  0.361
1985 Micklem K, Sim E, Sim RB. The generation of active fragments of complement receptor type 2 by trypsin digestion Febs Letters. 189: 195-201. PMID 3876241 DOI: 10.1016/0014-5793(85)81022-X  0.327
1985 Sim RB. Large-scale isolation of complement receptor type 1 (CR1) from human erythrocytes. Proteolytic fragmentation studies Biochemical Journal. 232: 883-889. PMID 2936334 DOI: 10.1042/Bj2320883  0.35
1985 Alsenz J, Schulz TF, Lambris JD, Sim RB, Dierich MP. Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H Biochemical Journal. 232: 841-850. PMID 2936333 DOI: 10.1042/Bj2320841  0.359
1985 Ezekowitz RAB, Sim RB, Macpherson GG, Gordon S. Interaction of human monocytes, macrophages, and polymorphonuclear leukocytes with zymosan in vitro. Role of type 3 complement receptors and macrophage-derived complement. Journal of Clinical Investigation. 76: 2368-2376. PMID 2934410 DOI: 10.1172/Jci112249  0.403
1985 Malhotra V, Sim RB. Expression of complement factor H on the cell surface of the human monocytic cell line U937 European Journal of Immunology. 15: 935-941. PMID 2412838 DOI: 10.1002/Eji.1830150913  0.352
1984 Cooper PD, Sim RB. Substances that can trigger activation of the alternative pathway of complement have anti-melanoma activity in mice International Journal of Cancer. 33: 683-687. PMID 6724743 DOI: 10.1002/Ijc.2910330520  0.338
1984 Ezekowitz RAB, Sim RB, Hill M, Gordon S. Local opsonization by secreted macrophage complement components. Role of receptors for complement in uptake of zymosan. Journal of Experimental Medicine. 159: 244-260. PMID 6319531 DOI: 10.1084/Jem.159.1.244  0.357
1984 Micklem KJ, Sim RB, Sim E. Analysis of C3-receptor activity on human B-lymphocytes and isolation of the complement receptor type 2 (CR2) Biochemical Journal. 224: 75-86. PMID 6239618 DOI: 10.1042/Bj2240075  0.357
1984 Fontaine M, Sim RB. Localisation of a group of antigenic sites in complement component C3, and identification of a new fragmentation pattern Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 789: 119-127. PMID 6206896 DOI: 10.1016/0167-4838(84)90195-X  0.338
1983 Sim E, Sim RB. Enzymic assay of C3b receptor on intact cells and solubilized cells Biochemical Journal. 210: 567-576. PMID 6222733 DOI: 10.1042/Bj2100567  0.358
1983 Sim RB, Sim E. Autolytic fragmentation of complement components C3 and C4 and its relationship to covalent binding activity Annals of the New York Academy of Sciences. 259-276. PMID 6202197 DOI: 10.1111/J.1749-6632.1983.Tb18114.X  0.385
1983 Sim E, Palmer MS, Puklavec M, Sim RB. Monoclonal antibodies against the complement control protein Factor H (β<inf>1</inf> H) Bioscience Reports. 3: 1119-1131. PMID 6199050 DOI: 10.1007/Bf01120205  0.367
1981 Sim E, Sim RB. Binding of fluid-phase complement components C3 and C3b to human lymphocytes Biochemical Journal. 198: 509-518. PMID 7326019 DOI: 10.1042/Bj1980509  0.392
1981 Sim RB, Twose TM, Paterson DS, Sim E. The covalent-binding reaction of complement component C3 Biochemical Journal. 193: 115-127. PMID 7305916 DOI: 10.1042/Bj1930115  0.382
1981 Davies SG, Sim RB. Intramolecular general acid catalysis in the binding reactions of α2 and complement components C3 and C4 Bioscience Reports. 1: 461-468. PMID 6170356 DOI: 10.1007/Bf01121579  0.377
1981 Whitehead AS, Sim RB, Bodmer WF. A monoclonal antibody against human complement component C3: the production of C3 by human cells in vitro. European Journal of Immunology. 11: 140-6. PMID 6163641 DOI: 10.1002/Eji.1830110215  0.355
1980 Sim RB, Arlaud GJ, Colomb MG. Kinetics of reaction of human C1-inhibitor with the human complement system proteases C1r and C1s Biochimica Et Biophysica Acta. 612: 433-449. PMID 6245704 DOI: 10.1016/0005-2744(80)90126-6  0.34
1979 Sim RB, Reboul A, Arlaud GJ, Villiers CL, Colomb MG. Interaction of 125I-labelled complement subcomponents C-1r and C-1s with protease inhibitors in plasma. Febs Letters. 97: 111-115. PMID 761607 DOI: 10.1016/0014-5793(79)80063-0  0.301
1979 Arlaud GJ, Reboul A, Sim RB, Colomb MG. Interaction of C1-inhibitor with the C1r and C1s subcomponents in human C1 Biochimica Et Biophysica Acta. 576: 151-162. PMID 760802 DOI: 10.1016/0005-2795(79)90494-X  0.357
1979 Sim RB, Arlaud GJ, Colomb MG. C1 inhibitor-dependent dissociation of human complement component C1 bound to immune complexes. Biochemical Journal. 179: 449-457. PMID 475762 DOI: 10.1042/Bj1790449A  0.352
1978 Dodds AW, Sim RB, Porter RR, Kerr MA. Activation of the first component of human complement (C1) by antibody-antigen aggregates. The Biochemical Journal. 175: 383-90. PMID 743203 DOI: 10.1042/Bj1750383  0.578
1977 Sim RB, Porter RR, Reid KB, Gigli I. The structure and enzymic activities of the C1r and C1s subcomponents of C1, the first component of human serum complement. The Biochemical Journal. 163: 219-27. PMID 869924 DOI: 10.1042/Bj1630219  0.667
1977 Reid KB, Sim RB, Faiers AP. Inhibition of the reconstitution of the haemolytic activity of the first component of human complement by a pepsin-derived fragment of subcomponent C1q. The Biochemical Journal. 161: 239-45. PMID 322655 DOI: 10.1042/Bj1610239  0.578
1976 Sim RB, Porter RR. Isolation and comparison of the proenzyme and activated forms of the human serum complement subcomponents C1r and C1s. Biochemical Society Transactions. 4: 127-9. PMID 1001616 DOI: 10.1042/Bst0040127  0.58
1976 Gigli I, Porter RR, Sim RB. The unactivated form of the first component of human complement, C1. The Biochemical Journal. 157: 541-8. PMID 985398 DOI: 10.1042/Bj1570541  0.594
Low-probability matches (unlikely to be authored by this person)
2005 Arnold JN, Royle L, Dwek RA, Rudd PM, Sim RB. Human immunoglobulin glycosylation and the lectin pathway of complement activation. Advances in Experimental Medicine and Biology. 564: 27-43. PMID 16400805 DOI: 10.1007/0-387-25515-X_9  0.3
1988 Perkins SJ, Haris PI, Sim RB, Chapman D. A study of the structure of human complement component factor H by Fourier transform infrared spectroscopy and secondary structure averaging methods. Biochemistry. 27: 4004-4012. PMID 2970865 DOI: 10.1021/Bi00411A017  0.299
2008 Breijo M, Anesetti G, Martínez L, Sim RB, Ferreira AM. Echinococcus granulosus: the establishment of the metacestode is associated with control of complement-mediated early inflammation. Experimental Parasitology. 118: 188-96. PMID 17905232 DOI: 10.1016/J.Exppara.2007.07.014  0.297
2000 Schwaeble WJ, Stover CM, Hanson S, Weiss EH, Sim RB. Genomic organisation of the human complement regulatory component factor H Immunopharmacology. 49: 13. DOI: 10.1016/S0162-3109(00)80029-6  0.297
2011 Rybak-Smith MJ, Tripisciano C, Borowiak-Palen E, Lamprecht C, Sim RB. Effect of functionalization of carbon nanotubes with psychosine on complement activation and protein adsorption. Journal of Biomedical Nanotechnology. 7: 830-9. PMID 22416583 DOI: 10.1166/Jbn.2011.1347  0.296
1987 Corton JM, Dobbie D, Gardner B, Merry AH, Sim RB. Monoclonal antibodies against complement component C3 Biochemical Society Transactions. 15: 653-654. DOI: 10.1042/Bst0150653  0.295
2000 Kojima M, Sim RB. Regulation of human MBL-MASPs by C1-inhibitor and α2-macroglobulin Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A492A  0.295
1997 Wong N, Sim RB. Comparison of the complement system protein complexes formed by C1q and MBL Biochemical Society Transactions. 25. PMID 9056939 DOI: 10.1042/Bst025041S  0.295
1985 Folkersen J, Sim RB, Sottrup-Jensen L, Svehag S. Application of the immunoblotting technique to the study of single protein species in complex biological fluids: A model study with alpha‐2‐macroglobulin Electrophoresis. 6: 227-234. DOI: 10.1002/Elps.1150060506  0.294
1993 Perkins SJ, Nealis AS, Smith KF, Sim RB. Solution structures of important multidomain proteins of the complement system by X-ray and neutron scattering Journal De Physique Iv. 3: 261-264. DOI: 10.1051/Jp4:1993851  0.293
1986 Jepsen HH, Svehag SE, Jensenius JC, Sim RB. Release of Immune Complexes bound to Erythrocyte Complement Receptor (CR1), with Particular Reference to the Role of Factor I Scandinavian Journal of Immunology. 24: 205-213. PMID 2944215 DOI: 10.1111/J.1365-3083.1986.Tb02087.X  0.291
1998 Ferreira AM, Breijo M, Sim RB, Nieto A. Contribution of C5-mediated mechanisms to host defense against the parasite Echinococcus granulosus Molecular Immunology. 35: 345. DOI: 10.1016/S0161-5890(98)90592-2  0.29
1997 Wong N, Sim RB. MBL circulates in human serum in a high molecular weight form that resembles a C1 complex Immunology Letters. 56: 112. DOI: 10.1016/S0165-2478(97)85447-8  0.289
2007 Brown KS, Ryder SD, Irving WL, Sim RB, Hickling TP. Mannan binding lectin and viral hepatitis. Immunology Letters. 108: 34-44. PMID 17157924 DOI: 10.1016/J.Imlet.2006.10.006  0.289
1999 Tedesco F, Fischetti F, Pausa M, Dobrina A, Sim RB, Daha MR. Complement-endothelial cell interactions: pathophysiological implications. Molecular Immunology. 36: 261-8. PMID 10403479 DOI: 10.1016/S0161-5890(99)90054-8  0.289
1991 Reid M, Mallinson G, Sim R, Poole J, Pausch V, Merry A, Liew Y, Tanner M. Biochemical studies on red blood cells from a patient with the Inab phenotype (decay-accelerating factor deficiency). Blood. 78: 3291-3297. DOI: 10.1182/Blood.V78.12.3291.Bloodjournal78123291  0.289
2009 Carlisle RC, Di Y, Cerny AM, Sonnen AF, Sim RB, Green NK, Subr V, Ulbrich K, Gilbert RJ, Fisher KD, Finberg RW, Seymour LW. Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1. Blood. 113: 1909-18. PMID 19131551 DOI: 10.1182/Blood-2008-09-178459  0.289
2005 Suckale J, Sim RB, Dodds AW. Evolution of innate immune systems*. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 33: 177-83. PMID 21638572 DOI: 10.1002/Bmb.2005.494033032466  0.288
1994 Sim RB, Malhotra R. Interactions of carbohydrates and lectins with complement Biochemical Society Transactions. 22: 106-111. PMID 8206200 DOI: 10.1042/Bst0220106  0.287
2000 Sim RB, Merry T, Rudd PM. Glycosylation of C1 Inhibitor Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A336B  0.287
1987 Ripoche J, Day AJ, Moffatt B, Sim RB. mRNA coding for a truncated form of human complement factor H Biochemical Society Transactions. 15: 651-652. DOI: 10.1042/Bst0150651  0.287
2011 Abuhammad A, Lack N, Schweichler J, Staunton D, Sim RB, Sim E. Improvement of the expression and purification of Mycobacterium tuberculosis arylamine N-acetyltransferase (TBNAT) a potential target for novel anti-tubercular agents. Protein Expression and Purification. 80: 246-52. PMID 21767648 DOI: 10.1016/J.Pep.2011.06.021  0.286
2009 Carroll MV, Krarup A, Sim E, Sim RB. Complement activation by Mycobacterium bovis BCG Molecular Immunology. 46: 2834. DOI: 10.1016/J.Molimm.2009.05.231  0.286
2001 Hajela K, Sim RB. Activity and regulation of human MBL associated serine protease1(MASP-1) Biochemical Society Transactions. 29. DOI: 10.1042/Bst029A129C  0.285
2008 Sheikh MA, Potter JA, Johnson KA, Sim RB, Boyd EF, Taylor GL. Crystal structure of VC1805, a conserved hypothetical protein from a Vibrio cholerae pathogenicity island, reveals homology to human p32. Proteins. 71: 1563-71. PMID 18300248 DOI: 10.1002/Prot.21993  0.284
1996 Whaley K, Sim RB, He S. Autoimmune C1-inhibitor deficiency Clinical and Experimental Immunology. 106: 423-426. PMID 8973607 DOI: 10.1046/J.1365-2249.1996.D01-879.X  0.284
2007 Prosser B, Johnson S, Roversi P, Herbert A, Blaum BS, Uhrin D, Tyrrell J, Clark S, Tarelli E, Barlow P, Sim RB, Day A, Lea SM. Towards a structural basis for complement factor H linked age-related macular degeneration Molecular Immunology. 44: 3930-3931. DOI: 10.1016/J.Molimm.2007.06.055  0.284
2010 Brown KS, Keogh MJ, Owsianka AM, Adair R, Patel AH, Arnold JN, Ball JK, Sim RB, Tarr AW, Hickling TP. Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry. Protein & Cell. 1: 664-74. PMID 21203938 DOI: 10.1007/S13238-010-0088-9  0.283
2008 Mayilyan KR, Dodds AW, Boyajyan AS, Soghoyan AF, Sim RB. Complement C4B protein in schizophrenia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 9: 225-30. PMID 17853297 DOI: 10.1080/15622970701227803  0.283
1984 MALHOTRA V, SIM RB. Role of complement receptor CR1 in the breakdown of soluble and zymosan-bound C3b Biochemical Society Transactions. 12: 781-782. DOI: 10.1042/Bst0120781  0.282
1979 Arlaud GJ, Sim RB, Duplaa A, Colomb MG. Differential elution of Clq, Cl̄r and Cl̄s from human CT bound to immune aggregates. use in the rapid purification of Cl̄ sub-components Molecular Immunology. 16: 445-450. PMID 40870 DOI: 10.1016/0161-5890(79)90069-5  0.281
2000 Irigoín F, Ferreira F, Laich A, Fernández C, Ferreira A, Sim RB, Díaz A. Characterization of an inhibitor of complement activation from the parasite Echinococcus granulosus Immunopharmacology. 49: 75. DOI: 10.1016/S0162-3109(00)80223-4  0.281
1990 Perkins SJ, Nealis AS, Sim RB. Molecular modeling of human complement component C4 and its fragments by X-ray and neutron solution scattering. Biochemistry. 29: 1167-1175. PMID 2322556 DOI: 10.1021/Bi00457A011  0.281
1997 Stuart GR, Lynch N, Schwaeble W, Sim RB. Localisation of the collectin binding site within C1q-receptor (collectin receptor) Immunology Letters. 56: 19. DOI: 10.1016/S0165-2478(97)85074-2  0.281
1988 Brazier DM, Merry AH, Sim RB. Serological and immunochemical assessment of anti-complement monoclonal antibodies Revue FrançAise De Transfusion Et Immuno-HéMatologie. 31: 369-376. PMID 3212316 DOI: 10.1016/S0338-4535(88)80124-7  0.28
1986 Perkins SJ, Sim RB. Molecular modelling of human complement component C3 and its fragments by solution scattering European Journal of Biochemistry / Febs. 157: 155-168. PMID 3486762 DOI: 10.1111/J.1432-1033.1986.Tb09652.X  0.28
2000 Trinder PKE, Hickling TP, Sim RB, Brackertz D, Loos M, Maeurer MJ. Humoral autoreactivity directed against surfactant protein-A (SP-A) in rheumatoid arthritis synovial fluids Clinical and Experimental Immunology. 120: 183-187. PMID 10759781 DOI: 10.1046/J.1365-2249.2000.01185.X  0.278
1989 Merry AH, Rawlinson VI, Uchikawa M, Watts MJ, Sim RB. Lack of abnormal sensitivity to complement-mediated lysis in erythrocytes deficient only in decay accelerating factor Biochemical Society Transactions. 17: 514-514. DOI: 10.1042/Bst0170514  0.276
1998 Vanderplasschen A, Mathew E, Hollinshead M, Sim RB, Smith GL. Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope Proceedings of the National Academy of Sciences of the United States of America. 95: 7544-7549. PMID 9636186 DOI: 10.1073/Pnas.95.13.7544  0.275
2007 Krarup A, Girija UV, Mitchell DA, Smith DF, Sim RB. Investigation of L-ficolin binding specificity Molecular Immunology. 44: 3959. DOI: 10.1016/J.Molimm.2007.06.119  0.274
2000 Clark HW, Reid KBM, Sim RB. Collectins and innate immunity in the lung. Microbes and Infection. 2: 273-278. PMID 10758403 DOI: 10.1016/S1286-4579(00)00301-4  0.273
2000 Tedesco F, Fischetti F, Pausa M, Dobrina A, Sim RB, Daha MR. Complement-endothelial cell interactions: pathophysiological implications: [Mol. Immunol. (1999) 36(4-5) 261-268] Molecular Immunology. 37. PMID 10781839 DOI: 10.1016/S0161-5890(00)00036-5  0.271
1995 Malhotra R, Sim RB. Collectins and viral infection Trends in Microbiology. 3: 240-244. PMID 7648033 DOI: 10.1016/S0966-842X(00)88932-5  0.27
2007 Shu X, Clark SJ, Dodds AW, Slingsby F, Day AJ, Sim RB, Wright AF. C1QTNF5, which is mutated in late-onset retinal macular degeneration, interacts with complement factor H Molecular Immunology. 44: 240. DOI: 10.1016/J.Molimm.2006.07.219  0.268
1991 Steinkasserer A, Estaller C, Weiss EH, Sim RB, Day AJ. Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I. Biochemical Journal. 277: 387-391. PMID 1650181 DOI: 10.1042/Bj2770387  0.268
1993 Sim RB, Kölble K, McAleer MA, Dominguez O, Dee VM. Genetics and deficiencies of the soluble regulatory proteins of the complement system. International Reviews of Immunology. 10: 65-86. PMID 8340678 DOI: 10.3109/08830189309051172  0.267
1979 Sim E, Sim RB. Hydrodynamic parameters of the detergent-solubilised hydrogenase from Paracoccus denitrificans European Journal of Biochemistry. 97: 119-126. PMID 477660 DOI: 10.1111/J.1432-1033.1979.Tb13092.X  0.267
2007 Carroll MV, Lack N, Sim E, Sim RB. Complement interaction with Mycobacterium bovis BCG Molecular Immunology. 44: 3975-3976. DOI: 10.1016/J.Molimm.2007.06.174  0.267
2002 Irigoín F, Ferreira F, Fernández C, Sim RB, Díaz A. myo-Inositol hexakisphosphate is a major component of an extracellular structure in the parasitic cestode Echinococcus granulosus. The Biochemical Journal. 362: 297-304. PMID 11853537 DOI: 10.1042/0264-6021:3620297  0.266
2003 Garred P, Nielsen MA, Kurtzhals JAL, Malhotra R, Madsen HO, Goka BQ, Akanmori BD, Sim RB, Hviid L. Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes. Infection and Immunity. 71: 5245-5253. PMID 12933871 DOI: 10.1128/Iai.71.9.5245-5253.2003  0.265
2007 Gulla KC, Willis AC, Hajela K, Sim RB. Ficolin-MASPs in complement and coagulation pathways Molecular Immunology. 44: 3957. DOI: 10.1016/J.Molimm.2007.06.114  0.264
2007 Schneider MC, Prosser B, Kugelberg E, Sim RB, Lea S, Tang CM. Interactions between factor H and Neisseria meningitidis Molecular Immunology. 44: 3980. DOI: 10.1016/J.Molimm.2007.06.184  0.263
1993 Perkins SJ, Smith KF, Kilpatrick JM, Volanakis JE, Sim RB. Modelling of the serine-proteinase fold by X-ray and neutron scattering and sedimentation analyses: occurrence of the fold in factor D of the complement system Biochemical Journal. 295: 87-99. PMID 8216242 DOI: 10.1042/Bj2950087  0.262
1998 Díaz A, Irigoín F, Ferreira F, Sim RB. A heat-stable inhibitor of factor B activation from the parasite Echinococcus granulosus Molecular Immunology. 35: 345. DOI: 10.1016/S0161-5890(98)90591-0  0.262
1981 Sim E, Wood AB, Hsiung LM, Sim RB. Pattern of degradation of human complement fragment, C3b. Febs Letters. 132: 55-60. PMID 6457754 DOI: 10.1016/0014-5793(81)80426-7  0.261
1991 Steinkasserer A, Koelble K, Sim RB. Length variation within intron 2 of the human IL-1 receptor antagonist protein gene (IL1RN) Nucleic Acids Research. 19: 5095. PMID 1833721 DOI: 10.1093/Nar/19.18.5095  0.261
2007 Fernando AN, Gilbert HE, Clark SJ, Day AJ, Sim RB, Perkins SJ. The AMD disease-associated His384Tyr polymorphism of factor H is predicted to be exposed in the bent solution structure of SCR 6–8 Molecular Immunology. 44: 168-169. DOI: 10.1016/J.Molimm.2006.07.054  0.261
2000 Díaz A, Willis AC, Sim RB. Expression of the proteinase specialized in bone resorption, cathepsin K, in granulomatous inflammation. Molecular Medicine. 6: 648-659. DOI: 10.1007/Bf03402045  0.261
1982 Sim RB, DiScipio RG. Purification and structural studies on the complement-system control protein β1H (factor H) Biochemical Journal. 205: 285-293. PMID 6215918 DOI: 10.1042/BJ2050285  0.261
1998 Breijo M, Spinelli P, Sim RB, Ferreira AM. Echinococcus granulosus: an intraperitoneal diffusion chamber model of secondary infection in mice. Experimental Parasitology. 90: 270-6. PMID 9806872 DOI: 10.1006/Expr.1998.4338  0.258
1988 Malhotra R, Reid KBM, Sim RB. Studies on the isolation of human C1q-receptor Biochemical Society Transactions. 16: 735-736. DOI: 10.1042/Bst0160735  0.258
1993 Weiss EH, Schwaeble W, Steinkasserer A, Sim RB. Genomic organization, evolution and sequence analysis of the human factor H gene familiy Molecular Immunology. 30: 62. DOI: 10.1016/0161-5890(93)90409-5  0.257
1977 Reboul A, Arlaud GJ, Sim RB, Colomb MG. A simplified procedure for the purification of C1̄‐inactivator from human plasma Interaction with complement subcomponents C1̄r and C1̄s Febs Letters. 79: 45-50. PMID 891934 DOI: 10.1016/0014-5793(77)80347-5  0.257
2018 Ali YM, Abd El-Aziz AM, Mabrook M, Shabaan AA, Sim RB, Hassan R. Recombinant chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) protects against LPS-induced lung injury in mice. Clinical Immunology (Orlando, Fla.). PMID 30145330 DOI: 10.1016/J.Clim.2018.08.009  0.255
2006 Neyen C, Plüddemann A, Thomas B, Akoulitchev A, Cai L, Westhuyzen DVD, Sim R, Gordon S. Th-P15:97 Identification of apolipoprotein A-I as A plasma ligand for macrophage scavenger receptor A Atherosclerosis Supplements. 7: 514-514. DOI: 10.1016/S1567-5688(06)82057-X  0.253
1993 Steinkasserer A, Dörner C, Würzner R, Sim RB. Human beta 2-glycoprotein I: molecular analysis of DNA and amino acid polymorphism. Human Genetics. 91: 401-402. PMID 8099061 DOI: 10.1007/Bf00217367  0.252
1997 Hickling TP, Malhotra R, Sim RB. A comparison of lung surfactant protein A (SP-A) from human bronchoalveolar lavage fluid and synovial fluid Immunology Letters. 56: 112-113. DOI: 10.1016/S0165-2478(97)85448-X  0.252
2011 Sim RB, Wallis R. Surface properties: Immune attack on nanoparticles. Nature Nanotechnology. 6: 80-1. PMID 21293484 DOI: 10.1038/Nnano.2011.4  0.251
2000 Tan LA, McGibbon N, Sim RB. Interaction of C1q with phospholipids (PL) Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A491A  0.25
1988 Erdei A, Bajtay Z, Fábry Z, Sim RB, Gergely J. Appearance of acceptor-bound C3b on HLA-DR positive macrophages and on stimulated U937 cells; inhibition of Fc gamma-receptors by the covalently fixed C3 fragments. Molecular Immunology. 25: 295-303. PMID 2967429 DOI: 10.1016/0161-5890(88)90021-1  0.249
1979 Agutter PS, Cockrill JB, Lavine JE, McCaldin B, Sim RB. Properties of mammalian nuclear-envelope nucleoside triphosphatase Biochemical Journal. 181: 647-658. PMID 229821 DOI: 10.1042/Bj1810647  0.248
2014 Ali YM, Hayat A, Saeed BM, Haleem KS, Alshamrani S, Kenawy HI, Ferreira VP, Saggu G, Buchberger A, Lachmann PJ, Sim RB, Goundis D, Andrew PW, Lynch NJ, Schwaeble WJ. Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection. Proceedings of the National Academy of Sciences of the United States of America. 111: 5301-6. PMID 24706855 DOI: 10.1073/Pnas.1401011111  0.247
1986 Jackson J, Sim RB, Whelan A, Feighery C. An IgG autoantibody which inactivates C1-inhibitor. Nature. 323: 722-4. PMID 3534579 DOI: 10.1038/323722A0  0.246
1992 Steinkasserer A, Solari R, Mott HR, Aplin RT, Robinson CC, Willis AC, Sim RB. Human interleukin-1 receptor antagonist. High yield expression in E. coli and examination of cysteine residues. Febs Letters. 310: 63-5. PMID 1388125 DOI: 10.1016/0014-5793(92)81147-E  0.245
1986 Day AJ, Sim RB. Inhibitory effect of Zn2+ ions on the degradation of the complement activation fragment C3b Biochemical Society Transactions. 14: 73-74. DOI: 10.1042/Bst0140073  0.245
2002 Eaton JT, Chamberlain D, Hinshelwood J, Sim RB, Perkins SJ. A molecular model for human factor B by constrained scattering modelling Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A119  0.245
1998 Lanzrein AS, Jobst KA, Thiel S, Jensenius JC, Sim RB, Perry VH, Sim E. Mannan-binding lectin in human serum, cerebrospinal fluid and brain tissue and its role in Alzheimer's disease. Neuroreport. 9: 1491-5. PMID 9631454 DOI: 10.1097/00001756-199805110-00045  0.244
2002 Presanis JS, Sim RB. Ficolin isolation from human serum Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A118A  0.243
2007 Mayilyan KR, Krarup A, Soghoyan AF, Hartung T, Sim RB. MBL and L-ficolin components of the complement activation lectin pathway in schizophrenia Molecular Immunology. 44: 3940. DOI: 10.1016/J.Molimm.2007.06.076  0.243
2009 Harvey DJ, Crispin M, Moffatt BE, Smith SL, Sim RB, Rudd PM, Dwek RA. Identification of high-mannose and multiantennary complex-type N-linked glycans containing alpha-galactose epitopes from Nurse shark IgM heavy chain. Glycoconjugate Journal. 26: 1055-64. PMID 19156518 DOI: 10.1007/S10719-008-9226-5  0.242
2009 Gentle ME, Gál P, Sim RB. Reactivity of MASP-1 and MASP-2 with serum protease inhibitors Molecular Immunology. 46: 2850. DOI: 10.1016/J.Molimm.2009.05.274  0.242
1998 Guerin J, Sim RB, Feighery C, Jackson J. Antibody reactivity to RCA cluster proteins in patients with the antiphospholipid syndrome Molecular Immunology. 35: 363. DOI: 10.1016/S0161-5890(98)90663-0  0.242
1997 Willis AC, Diaz A, Nieto A, Sim RB. Echinococcus granulosus antigen 5 may be a serine proteinase Parasite Immunology. 19: 385. PMID 9340598 DOI: 10.1046/J.1365-3024.1997.D01-222.X  0.241
1997 Guerin J, Feighery C, Sim RB, Jackson J. Antibodies to β2‐glycoprotein I—a specific marker for the antiphospholipid syndrome Clinical and Experimental Immunology. 109: 304-309. PMID 9276526 DOI: 10.1046/J.1365-2249.1997.4601357.X  0.24
1992 Steinkasserer A, Estaller C, Weiss EH, Sim RB. Human interleukin-1 receptor antagonist is expressed in liver. Febs Letters. 310: 60-62. PMID 1382023 DOI: 10.1016/0014-5793(92)81146-D  0.238
2013 Ansari M, McKeigue PM, Skerka C, Hayward C, Rudan I, Vitart V, Polasek O, Armbrecht AM, Yates JR, Vatavuk Z, Bencic G, Kolcic I, Oostra BA, Van Duijn CM, Campbell S, ... ... Sim RB, et al. Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration. Human Molecular Genetics. 22: 4857-69. PMID 23873044 DOI: 10.1093/Hmg/Ddt336  0.238
1997 Williams JL, Lester D, Teres VM, Barendse W, Sim RB, Soames CJ. Mapping the bovine factor H gene to Chromosome 16 by SSCP analysis Mammalian Genome. 8: 77-78. PMID 9021164 DOI: 10.1007/S003359900360  0.238
1992 Steinkasserer A, Spurr NK, Cox S, Jeggo P, Sim RB. The human IL-1 receptor antagonist gene (IL1RN) maps to chromosome 2q14-q21, in the region of the IL-1 alpha and IL-1 beta loci. Genomics. 13: 654-7. PMID 1386337 DOI: 10.1016/0888-7543(92)90137-H  0.236
2008 Pascu SI, Waghorn PA, Conry TD, Lin B, Betts HM, Dilworth JR, Sim RB, Churchill GC, Aigbirhio FI, Warren JE. Cellular confocal fluorescence studies and cytotoxic activity of new Zn(II) bis(thiosemicarbazonato) complexes. Dalton Transactions (Cambridge, England : 2003). 2107-10. PMID 18398535 DOI: 10.1039/B802806K  0.236
2009 Cole MA, Tully SE, Dodds AW, Arnold JN, Boldt GE, Sim RB, Offer J, Wentworth P. Cover Picture: A Chemical Approach to Immunoprotein Engineering: Chemoselective Functionalization of Thioester Proteins in Their Native State (ChemBioChem 8/2009) Chembiochem. 10: 1265-1265. DOI: 10.1002/Cbic.200990027  0.231
2010 Hong SY, Tobias G, Al-Jamal KT, Ballesteros B, Ali-Boucetta H, Lozano-Perez S, Nellist PD, Sim RB, Finucane C, Mather SJ, Green ML, Kostarelos K, Davis BG. Filled and glycosylated carbon nanotubes for in vivo radioemitter localization and imaging. Nature Materials. 9: 485-90. PMID 20473287 DOI: 10.1038/Nmat2766  0.23
1997 Trinder PKE, Hickling TP, Sim RB, Brackertz D, Maeurer MJ, Loos M. Evidence for auto-reactivity against the collectins, SP-A and MBL, in rheumatoid arthritis synovial fluids: Lack of cross-reactivity with C1q or type II collagen Immunology Letters. 56: 112. DOI: 10.1016/S0165-2478(97)85445-4  0.229
2006 Basiuk VA, Salvador-Morales C, Basiuk EV, Jacobs RMJ, Ward M, Chu BT, Sim RB, Green MLH. 'Green' derivatization of carbon nanotubes with Nylon 6 and l-alanine Journal of Materials Chemistry. 16: 4420-4426. DOI: 10.1039/B611562D  0.229
2008 Khoyetsyan AG, Boyadzhyan AS, Tsakanova GV, Sim RB. Abnormal immune complexes in schizophrenia Neurochemical Journal. 2: 329-330. DOI: 10.1134/S1819712408040284  0.225
1993 Steinkasserer A, Spurr NK, Sim RB. Chromosomal mapping of the human interleukin-1 receptor antagonist gene (IL-1RN) and isolation of specific YAC clones Agents and Actions. 38. PMID 8317324 DOI: 10.1007/Bf01991137  0.224
2004 Irigoín F, Casaravilla C, Iborra F, Sim RB, Ferreira F, Díaz A. Unique precipitation and exocytosis of a calcium salt of myo-inositol hexakisphosphate in larval Echinococcus granulosus. Journal of Cellular Biochemistry. 93: 1272-81. PMID 15486919 DOI: 10.1002/Jcb.20262  0.221
1982 Sim R, Sim E, Whitehead A. WM1 monoclonal antibody inhibits the binding of activated C3 to surfaces Molecular Immunology. 19: 1402. DOI: 10.1016/0161-5890(82)90150-X  0.218
2015 Würzner R, Tedesco F, Garred P, Mollnes TE, Truedsson L, Turner MW, Sommarin Y, Wieslander J, Sim RB. European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha. Molecular Immunology. 68: 63-6. PMID 26006049 DOI: 10.1016/J.Molimm.2015.05.003  0.218
1981 Sim RB, Sim E. Autolytic fragmentation of complement components C3 and C4 under denaturing conditions, a property shared with α2-macroglobulin Biochemical Journal. 193: 129-141. PMID 7305917 DOI: 10.1042/BJ1930129  0.216
2002 Hajela K, Sim RB. Substrate specificity of MASP-1 Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A117B  0.215
2022 Sim R, Twose TM, Sim E, Reid KBM. Intrinsic chemical reactivity of activated human complement component C3: A historical glimpse into research during 1979-1980 on the covalent binding properties of C3, C4 and alpha-2 macroglobulin. Immunobiology. 227: 152209. PMID 35841752 DOI: 10.1016/j.imbio.2022.152209  0.213
2008 Mayilyan KR, Weinberger DR, Sim RB. The complement system in schizophrenia. Drug News & Perspectives. 21: 200-10. PMID 18560619 DOI: 10.1358/Dnp.2008.21.4.1213349  0.212
2000 Laich A, Sim RB. Investigation of C4bC2 complex formation by surface plasmon resonance Immunopharmacology. 49: 42. DOI: 10.1016/S0162-3109(00)80117-4  0.209
2017 Tsakanova G, Stepanyan A, Nahapetyan K, Sim RB, Arakelyan A, Boyajyan A. Serine proteases of the complement lectin pathway and their genetic variations in ischaemic stroke. Journal of Clinical Pathology. PMID 28720568 DOI: 10.1136/Jclinpath-2017-204403  0.209
2000 Schwaeble WJ, Schäfer MK-, Post C, Salvati P, Calabresi M, Sim RB, Petry F, Loos M, Weihe E. Complement C1q is dramatically upregulated in brain microglia in response to transient global cerebral ischemia Immunopharmacology. 49: 15. DOI: 10.1016/S0162-3109(00)80038-7  0.205
2002 Díaz A, Willis AC, Sim RB. Cathepsin K expression in epithelioid and multinucleated giant cells. The Journal of Pathology. 197: 690; author reply 69. PMID 12210091 DOI: 10.1002/Path.1143  0.2
1991 Kölble K, Sim RB. An angle-variable three-dimensional pulsed field gel electrophoresis system Analytical Biochemistry. 192: 32-38. PMID 2048730 DOI: 10.1016/0003-2697(91)90178-V  0.197
1992 Steinkasserer A, Cockburn DJ, Black DM, Boyd Y, Solomon E, Sim RB. Assignment of apolipoprotein H (APOH: beta-2-glycoprotein I) to human chromosome 17q23----qter; determination of the major expression site. Cytogenetics and Cell Genetics. 60: 31-3. PMID 1582254 DOI: 10.1159/000133289  0.194
2009 Gál P, Dobó J, Závodszky P, Sim RB. Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions. Molecular Immunology. 46: 2745-52. PMID 19477526 DOI: 10.1016/j.molimm.2009.04.026  0.184
1981 Sim RB. The first component of human complement--C1 Methods in Enzymology. 80: 6-16. PMID 7043203 DOI: 10.1016/S0076-6879(81)80004-3  0.183
1981 Sim RB. The human complement system serine proteases C1r and C1s and their proenzymes Methods in Enzymology. 80: 26-42. PMID 6281620 DOI: 10.1016/S0076-6879(81)80006-7  0.181
1985 Al-Abdullah IH, Sim RB, Sheil J, Greally JF. The effect of danazol on the production of C1 inhibitor in the guinea pig. Complement (Basel, Switzerland). 1: 27-35. PMID 6399878 DOI: 10.1159/000467811  0.176
2006 Mayilyan KR, Presanis JS, Arnold JN, Sim RB. Discrete MBL-MASP complexes show wide inter-individual variability in concentration: data from UK vs Armenian populations. International Journal of Immunopathology and Pharmacology. 19: 567-80. PMID 17026842 DOI: 10.1177/039463200601900313  0.176
1981 Sim RB, Reboul A. Preparation and properties of human C1 inhibitor Methods in Enzymology. 80: 43-54. PMID 6281621 DOI: 10.1016/S0076-6879(81)80007-9  0.159
2022 Karagianni EP, Kontomina E, Lowe ED, Athanasopoulos K, Papanikolaou G, Garefalaki V, Kotseli V, Zaliou S, Grimaud T, Arvaniti K, Tsatiri MA, Fakis G, Glenn AE, Roversi P, Abuhammad A, ... ... Sim RB, et al. Fusarium verticillioides NAT1 (FDB2) N-malonyltransferase is structurally, functionally and phylogenetically distinct from its N-acetyltransferase (NAT) homologues. The Febs Journal. PMID 36178468 DOI: 10.1111/febs.16642  0.158
1986 Ripoche J, Sim RB. Loss of complement receptor type 1 (CR1) on ageing of erythrocytes Biochemical Journal. 235: 815-821. PMID 2944510 DOI: 10.1042/BJ2350815  0.15
2013 Schwaeble WJ, Ali YM, Sim RB. The Roles and Contributions of the Complement System in the Pathophysiology of Autoimmune Diseases The Autoimmune Diseases: Fifth Edition. 217-227. DOI: 10.1016/B978-0-12-384929-8.00015-0  0.143
2009 Hamed M, Tarr A, Brown R, Krarup A, McClure C, Irving W, Sim R, Hickling T. 879 ROLE OF SOLUBLE LECTIN L-FICOLIN IMMUNE RECOGNITION IN HEPATITIS C VIRUS INFECTION Journal of Hepatology. 50: S320. DOI: 10.1016/S0168-8278(09)60881-3  0.142
1993 Sim RB. Activators and inhibitors of Complement Annals of Oncology. 4: 523-523. DOI: 10.1093/OXFORDJOURNALS.ANNONC.A058571  0.132
1986 SIM E, DODDS AW, WOOD M, SIM RB. Rapid purification of C4 from individual donors Biochemical Society Transactions. 14: 77-78. DOI: 10.1042/BST0140077  0.118
1993 Sim RB, Day AJ, Moffatt BE, Fontaine M. Complement factor I and cofactors in control of complement system convertase enzymes. Methods in Enzymology. 223: 13-35. PMID 8271948 DOI: 10.1016/0076-6879(93)23035-L  0.117
2023 Mayilyan KR, Krarup A, Soghoyan AF, Jensenius JC, Sim RB. l-ficolin-MASP arm of the complement system in schizophrenia. Immunobiology. 228: 152349. PMID 36805857 DOI: 10.1016/j.imbio.2023.152349  0.113
1998 Wong N, Dóbo J, Sim R. Interaction of MBL-associated serine proteases (MASPs) with synthetic and natural substrates and inhibitors Molecular Immunology. 35: 375. DOI: 10.1016/S0161-5890(98)90712-X  0.106
2003 Mayilyan K, Boyajyan A, Hakopyan S, Soghoyan A, Sim R. Complement system and circulating immune complexes under schizophrenia: Family study Schizophrenia Research. 60: 64-65. DOI: 10.1016/S0920-9964(03)80577-7  0.091
2000 Hickling TP, Bright H, Wing K, Gower D, Martin SL, Sim RB, Malhotra R. SP-A and SP-D modulate the infectivity of RSV Biochemical Society Transactions. 28: A490-A490. DOI: 10.1042/BST028A490A  0.071
2020 Peart JM, Sim R. Lipiodol hysterosalpingogram: A modified HSG technique to minimize risks associated with lipiodol use. Journal of Medical Imaging and Radiation Oncology. PMID 32613722 DOI: 10.1111/1754-9485.13080  0.04
1993 Mulherin D, FitzGerald O, Bresnihan B, Yanni G, Farahat M, Posten R, Panayi GS, Abuzakouk M, Feighery C, Casey E, Weir D, Farrelly CO, Bell AL, Magill KM, McKane JR, ... ... Sim RB, et al. Irish association of rheumatology & rehabilitation Irish Journal of Medical Science. 162: 321-332. DOI: 10.1007/bf02960730  0.022
2020 Peart J, Sim R. Safety of Lipiodol use for assessment of tubal patency and therapeutic tubal flushing - Fluoroscopy versus ultrasound? Journal of Medical Imaging and Radiation Oncology. PMID 32220042 DOI: 10.1111/1754-9485.13025  0.022
2023 Sim R. Leprosy of Ancient and Modern Times. The North American Medico-Chirurgical Review. 3: 876-878. PMID 38079894  0.015
2019 White RW, Fourney A, Herring A, Bennett PN, Chandrasekaran N, Sim R, Nouri E, Encarnación MJ. Multi-device digital assistance Communications of the Acm. 62: 28-31. DOI: 10.1145/3357159  0.013
1995 Abuzakouk M, Feighery C, Jones E, O’Briain S, Goggins M, Weir DG, Case E, O’Farrelly C, Weir DG, Casey E, Donnelly S, McGonigle D, Casey EB, Kelleher D, McCreary C, ... ... Sim RB, et al. Irish society for rheumatology Proceedings of Annual General Meeting held 14th October, 1994 at St. James’s Hospital, Dublin 8 Irish Journal of Medical Science. 164: 89-99. DOI: 10.1007/BF02968124  0.01
Hide low-probability matches.