Claude P Lechene, M.D. Ph.D. - Publications

Affiliations: 
Medicine Harvard University, Cambridge, MA, United States 
Website:
https://nano.bwh.harvard.edu/lab-people

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Guillermier C, Fazeli PK, Kim S, Lun M, Zuflacht JP, Milian J, Lee H, Francois-Saint-Cyr H, Horreard F, Larson D, Rosen ED, Lee RT, Lechene CP, Steinhauser ML. Imaging mass spectrometry demonstrates age-related decline in human adipose plasticity. Jci Insight. 2: e90349. PMID 28289709 DOI: 10.1172/Jci.Insight.90349  0.302
2014 Saiardi A, Guillermier C, Loss O, Poczatek JC, Lechene C. Quantitative imaging of inositol distribution in yeast using multi‐isotope imaging mass spectrometry (MIMS) Surface and Interface Analysis. 46: 169-172. PMID 26379342 DOI: 10.1002/Sia.5659  0.325
2014 Steinhauser ML, Guillermier C, Wang M, Lechene CP. Approaches to increasing analytical throughput of human samples with multi-isotope imaging mass spectrometry. Surface and Interface Analysis : Sia. 46: 165-168. PMID 26379341 DOI: 10.1002/Sia.5580  0.332
2014 Steinhauser ML, Guillermier C, Wang M, Lechene CP. Quantifying cell division with deuterated water and multi-isotope imaging mass spectrometry (MIMS). Surface and Interface Analysis : Sia. 46: 161-164. PMID 26379340 DOI: 10.1002/Sia.5581  0.323
2014 Tang SS, Guillermier C, Wang M, Poczatek JC, Suzuki N, Loscalzo J, Lechene C. Quantitative imaging of selenoprotein with multi-isotope imaging mass spectrometry (MIMS). Surface and Interface Analysis : Sia. 46: 154-157. PMID 26379338 DOI: 10.1002/Sia.5625  0.316
2012 Steinhauser ML, Bailey AP, Senyo SE, Guillermier C, Perlstein TS, Gould AP, Lee RT, Lechene CP. Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism. Nature. 481: 516-9. PMID 22246326 DOI: 10.1038/Nature10734  0.319
2012 Zhang DS, Piazza V, Perrin BJ, Rzadzinska AK, Poczatek JC, Wang M, Prosser HM, Ervasti JM, Corey DP, Lechene CP. Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia. Nature. 481: 520-4. PMID 22246323 DOI: 10.1038/Nature10745  0.313
2011 Lechene C. Seeing and Measuring Stable Isotope Tags in Subcellular Domains with Ion Microscopy Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.405  0.313
2004 Peteranderl R, Lechene C. Measure of Carbon and Nitrogen Stable Isotope Ratios in Cultured Cells Journal of the American Society For Mass Spectrometry. 15: 478-485. PMID 15047053 DOI: 10.1016/J.Jasms.2003.11.019  0.305
1997 Baltz JM, Smith SS, Biggers JD, Lechene C. Intracellular ion concentrations and their maintennance by Na + /K + -ATPase in preimplantation mouse embroys Zygote. 5: 1-9. DOI: 10.1017/S0967199400003506  0.35
1993 Biggers JD, Lawitts JA, Lechene CP. The Protective Action Of Betaine On The Deleterious Effects Of Nacl On Preimplantation Mouse Embryos In Vitro Molecular Reproduction and Development. 34: 380-390. PMID 8471260 DOI: 10.1002/Mrd.1080340406  0.339
1993 Mroz EA, Lechene C. Extracellular N-methyl-d-glucamine leads to loss of hair-cell sodium, potassium, and chloride Hearing Research. 70: 146-150. PMID 8294258 DOI: 10.1016/0378-5955(93)90152-Q  0.35
1993 Mroz EA, Lechene C. Calcium and magnesium transport by isolated goldfish hair cells Hearing Research. 70: 139-145. PMID 8294257 DOI: 10.1016/0378-5955(93)90151-P  0.35
1993 Mroz EA, Nissim KR, Lechene C. Rapid resting ion fluxes in goldfish hair cells are balanced by (Na+,K+)-ATPase. Hearing Research. 70: 22-30. PMID 8276730 DOI: 10.1016/0378-5955(93)90049-7  0.377
1993 Mroz EA, Nissim KR, Lechene C. Electron-probe analysis of isolated goldfish hair cells: Implications for preparing healthy cells Hearing Research. 70: 9-21. PMID 7506249 DOI: 10.1016/0378-5955(93)90048-6  0.374
1992 Schwartz MA, Lechene C. Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor Proceedings of the National Academy of Sciences of the United States of America. 89: 6138-6141. PMID 1378621 DOI: 10.1073/Pnas.89.13.6138  0.305
1990 Ingber DE, Prusty D, Frangioni JV, Cragoe EJ, Lechene C, Schwartz MA. Control of intracellular pH and growth by fibronectin in capillary endothelial cells. The Journal of Cell Biology. 110: 1803-11. PMID 2159481 DOI: 10.1083/Jcb.110.5.1803  0.312
1990 Baltz JM, Biggers JD, Lechene C. Apparent absence of Na+H+ antiport activity in the two-cell mouse embryo Developmental Biology. 138: 421-429. PMID 2156738 DOI: 10.1016/0012-1606(90)90208-Z  0.334
1990 Larsson SH, Rane S, Fukuda Y, Aperia A, Lechene C. Changes in Na influx precede post-natal increase in Na, K-ATPase activity in rat renal proximal tubular cells. Acta Physiologica Scandinavica. 138: 99-100. PMID 2155519 DOI: 10.1111/J.1748-1716.1990.Tb08819.X  0.361
1990 Cohen BJ, Lechene C. Alanine stimulation of passive potassium efflux in hepatocytes is independent of Na(+)-K+ pump activity. American Journal of Physiology-Cell Physiology. 258. PMID 2154112 DOI: 10.1152/Ajpcell.1990.258.1.C24  0.337
1989 Schwartz MA, Both G, Lechene C. Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 86: 4525-4529. PMID 2734302 DOI: 10.1073/Pnas.86.12.4525  0.302
1989 Rome L, Grantham J, Savin V, Lohr J, Lechene C. Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. American Journal of Physiology-Cell Physiology. 257. PMID 2610250 DOI: 10.1152/Ajpcell.1989.257.6.C1093  0.37
1989 Gardner DK, Clarke RN, Lechene CP, Biggers JD. Development of a noninvasive ultramicrofluorometric method for measuring net uptake of glutamine by single preimplantation mouse embryos Gamete Research. 24: 427-438. PMID 2591860 DOI: 10.1002/Mrd.1120240409  0.32
1989 Larsson SH, Larsson L, Lechene C, Aperia A. Studies of terminal differentiation of electrolyte transport in the renal proximal tubule using short-term primary cultures. Pediatric Nephrology. 3: 363-368. PMID 2562016 DOI: 10.1007/Bf00858547  0.363
1989 Mangoo-Karim R, Uchic M, Lechene C, Grantham JJ. Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP. Proceedings of the National Academy of Sciences of the United States of America. 86: 6007-6011. PMID 2474825 DOI: 10.1073/Pnas.86.15.6007  0.344
1989 Cohen BJ, Lechene C. (Na,K)-pump: cellular role and regulation in nonexcitable cells Biology of the Cell. 66: 191-195. DOI: 10.1111/J.1768-322X.1989.Tb00834.X  0.362
1988 Fukuda Y, Larsson S, Celsi G, Lechene C, Aperia A. Use of experimental models to study the development of renal function. Neonatology. 53: 197-200. PMID 3416020 DOI: 10.1159/000242791  0.318
1988 Heyman SN, Brezis M, Reubinoff CA, Greenfeld Z, Lechene C, Epstein FH, Rosen S. Acute renal failure with selective medullary injury in the rat. Journal of Clinical Investigation. 82: 401-412. PMID 3403711 DOI: 10.1172/Jci113612  0.301
1988 Larsson SH, Aperia A, Lechene C. Studies on terminal differentiation of rat renal proximal tubular cells in culture: ouabain-sensitive K and Na transport. Acta Physiologica Scandinavica. 132: 129-134. PMID 2852433 DOI: 10.1111/J.1748-1716.1988.Tb08309.X  0.358
1988 Epstein JA, Lechene C. Ouabain-resistant, amiloride-sensitive Na+-K+ pumping activity and morphological changes are inducible. The American Journal of Physiology. 254: C847-54. PMID 2454031 DOI: 10.1152/Ajpcell.1988.254.6.C847  0.331
1987 Bolívar JJ, Lázaro A, Fernández S, Stefani E, Peña-Cruz V, Lechene C, Cereijido M. Rescue of a wild-type MDCK cell by a ouabain-resistant mutant. The American Journal of Physiology. 253: C151-61. PMID 3300360 DOI: 10.1152/Ajpcell.1987.253.1.C151  0.328
1986 Larsson L, Aperia A, Lechene C. Ionic transport in individual renal epithelial cells from adult and young rats. Acta Physiologica Scandinavica. 126: 321-332. PMID 3962681 DOI: 10.1111/J.1748-1716.1986.Tb07823.X  0.371
1986 Larsson S, Aperia A, Lechene C. Studies on final differentiation of rat renal proximal tubular cells in culture. American Journal of Physiology-Cell Physiology. 251: 455-464. PMID 3019149 DOI: 10.1152/Ajpcell.1986.251.3.C455  0.359
1986 Harris RC, Seifter JL, Lechene C. Coupling of Na-H exchange and Na-K pump activity in cultured rat proximal tubule cells. American Journal of Physiology-Cell Physiology. 251. PMID 2430465 DOI: 10.1152/Ajpcell.1986.251.5.C815  0.357
1985 Abraham EH, Breslow JL, Epstein J, Chang-Sing P, Lechene C. Preparation of individual human diploid fibroblasts and study of ion transport. American Journal of Physiology-Cell Physiology. 248. PMID 3966540 DOI: 10.1152/Ajpcell.1985.248.1.C154  0.389
1983 Ichikawa I, Rennke HG, Hoyer JR, Badr KF, Schor N, Troy JL, Lechene CP, Brenner BM. Role for intrarenal mechanisms in the impaired salt excretion of experimental nephrotic syndrome. Journal of Clinical Investigation. 71: 91-103. PMID 6848563 DOI: 10.1172/Jci110756  0.32
1983 Jenkins AD, Lechene CP, Howards SS. The effect of spironolactone on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis and epididymis of the rat. The Journal of Urology. 129: 851-4. PMID 6842723 DOI: 10.1016/S0022-5347(17)52398-8  0.353
1983 Jenkins AD, Lechene CP, Howards SS. The effect of estrogen administration in vivo on the elemental composition of the intraluminal fluids of the seminiferous tubules, rete testis, and epididymis of the rat. Journal of Andrology. 4: 272-5. PMID 6618997 DOI: 10.1002/J.1939-4640.1983.Tb02366.X  0.304
1982 Warner RR, Lechene C. Analysis of standing droplets in rat proximal tubules. The Journal of General Physiology. 79: 709-35. PMID 7069399 DOI: 10.1085/Jgp.79.4.709  0.356
1980 Bonventre JV, Lechene C. Renal medullary concentrating process: an integrative hypothesis. American Journal of Physiology-Renal Physiology. 239. PMID 7446733 DOI: 10.1152/Ajprenal.1980.239.6.F578  0.306
1980 Warner RR, Lechene C. Isosmotic volume reabsorption in rat proximal tubule. The Journal of General Physiology. 76: 559-86. PMID 7441196 DOI: 10.1085/Jgp.76.5.559  0.305
1980 Borland RM, Biggers JD, Lechene CP, Taymor ML. Elemental composition of fluid in the human Fallopian tube. Reproduction. 58: 479-482. PMID 7431281 DOI: 10.1530/Jrf.0.0580479  0.335
1980 Bengele HH, Lechene C, Alexander EA. Sodium and chloride transport along the inner medullary collecting duct: effect of saline expansion. American Journal of Physiology-Renal Physiology. 238. PMID 7386629 DOI: 10.1152/Ajprenal.1980.238.6.F504  0.304
1980 Burgoyne PS, Borland RM, Biggers JD, Lechene CP. Elemental composition of rabbit antral fluid during preovulatory follicular swelling. Journal of Reproduction and Fertility. 57: 515-23. PMID 513038 DOI: 10.1530/Jrf.0.0570515  0.32
1979 Bengele HH, Lechene CP, Alexander EA. Phosphate transport along the inner medullary collecting duct of the rat American Journal of Physiology-Renal Physiology. 237. PMID 464060 DOI: 10.1152/Ajprenal.1979.237.1.F48  0.301
1978 Biggers JD, Borland RM, Lechene CP. Ouabain-sensitive fluid accumulation and ion transport by rabbit blastocysts. The Journal of Physiology. 280: 319-330. PMID 690882 DOI: 10.1113/Jphysiol.1978.Sp012386  0.359
1977 Chong AP, Taymor ML, Lechene CP. Electron probe microanalysis of the chemical elemental content of human follicular fluid American Journal of Obstetrics and Gynecology. 128: 209-211. PMID 855870 DOI: 10.1016/0002-9378(77)90690-1  0.321
1977 Stolte H, Galaske RG, Eisenbach GM, Lechene C, Schmidt‐Nielsen B, Boylan JW, Antkowiak D, Patel Y, Niermann U. Renal tubule ion transport and collecting duct function in the elasmobranch little skate, Raja erinacea Journal of Experimental Zoology. 199: 403-410. PMID 850120 DOI: 10.1002/Jez.1401990314  0.303
1977 Greger RF, Lang FC, Knox FG, Lechene CP. Absence of significant secretory flux of phosphate in the proximal convoluted tubule American Journal of Physiology-Renal Physiology. 232. PMID 842671 DOI: 10.1152/Ajprenal.1977.232.3.F235  0.326
1977 Lechene CP, Bronner C, Kirk RG. Electron probe microanalysis of chemical elemental content of single human red cells Journal of Cellular Physiology. 90: 117-126. PMID 833208 DOI: 10.1002/Jcp.1040900114  0.301
1977 Borland RM, Biggers JD, Lechene CP. Studies on the composition and formation of mouse blastocoele fluid using electron probe microanalysis. Developmental Biology. 55: 1-8. PMID 832766 DOI: 10.1016/0012-1606(77)90315-3  0.354
1977 Borland RM, Hazra S, Biggers JD, Lechene CP. The elemental composition of the environments of the gametes and preimplantation embryo during the initiation of pregnancy. Biology of Reproduction. 16: 147-57. PMID 831844 DOI: 10.1095/Biolreprod16.2.147  0.341
1976 Borland RM, Biggers JD, Lechene CP. Kinetic aspects of rabbit blastocoele fluid accumulation: an application of electron probe microanalysis. Developmental Biology. 50: 201-211. PMID 1269828 DOI: 10.1016/0012-1606(76)90078-6  0.362
1976 Roblero L, Biggers JD, Lechene CP. Electron probe analysis of the elemental microenvironment of oviducal mouse embryos. Reproduction. 46: 431-434. PMID 1255572 DOI: 10.1530/Jrf.0.0460431  0.334
Show low-probability matches.