Year |
Citation |
Score |
2024 |
Yu Y, Gao SM, Guan Y, Hu PW, Zhang Q, Liu J, Jing B, Zhao Q, Sabatini DM, Abu-Remaileh M, Jung SY, Wang MC. Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity. Elife. 13. PMID 38240316 DOI: 10.7554/eLife.85214 |
0.485 |
|
2022 |
Laqtom NN, Dong W, Medoh UN, Cangelosi AL, Dharamdasani V, Chan SH, Kunchok T, Lewis CA, Heinze I, Tang R, Grimm C, Dang Do AN, Porter FD, Ori A, Sabatini DM, ... Abu-Remaileh M, et al. CLN3 is required for the clearance of glycerophosphodiesters from lysosomes. Nature. PMID 36131016 DOI: 10.1038/s41586-022-05221-y |
0.481 |
|
2022 |
Kanarek N, Keys HR, Cantor JR, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Freinkman E, Schweitzer LD, Sabatini DM. Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity. Nature. PMID 35017686 DOI: 10.1038/s41586-021-03487-2 |
0.409 |
|
2020 |
Fassl A, Brain C, Abu-Remaileh M, Stukan I, Butter D, Stepien P, Feit AS, Bergholz J, Michowski W, Otto T, Sheng Q, Loo A, Michael W, Tiedt R, DeAngelis C, et al. Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition. Science Advances. 6: eabb2210. PMID 32704543 DOI: 10.1126/Sciadv.Abb2210 |
0.511 |
|
2020 |
Ansari I, Raddatz G, Gutekunst J, Ridnik M, Cohen D, Abu-Remaileh M, Tuganbaev T, Shapiro H, Pikarsky E, Elinav E, Lyko F, Bergman Y. The microbiota programs DNA methylation to control intestinal homeostasis and inflammation. Nature Microbiology. PMID 32015497 DOI: 10.1038/S41564-019-0659-3 |
0.598 |
|
2020 |
Weber RA, Yen FS, Nicholson SPV, Alwaseem H, Bayraktar EC, Alam M, Timson RC, La K, Abu-Remaileh M, Molina H, Birsoy K. Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation. Molecular Cell. PMID 31983508 DOI: 10.1016/J.Molcel.2020.01.003 |
0.633 |
|
2019 |
Rogala KB, Gu X, Kedir JF, Abu-Remaileh M, Bianchi LF, Bottino AMS, Dueholm R, Niehaus A, Overwijn D, Fils AP, Zhou SX, Leary D, Laqtom NN, Brignole EJ, Sabatini DM. Structural basis for the docking of mTORC1 on the lysosomal surface. Science (New York, N.Y.). PMID 31601708 DOI: 10.1126/Science.Aay0166 |
0.711 |
|
2018 |
Bayraktar EC, Baudrier L, Özerdem C, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Cangelosi AL, Sabatini DM, Birsoy K, Chen WW. MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 30541894 DOI: 10.1073/Pnas.1816656115 |
0.669 |
|
2018 |
Kanarek N, Keys HR, Cantor JR, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Freinkman E, Schweitzer LD, Sabatini DM. Histidine catabolism is a major determinant of methotrexate sensitivity. Nature. PMID 29995852 DOI: 10.1038/S41586-018-0316-7 |
0.581 |
|
2018 |
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, et al. Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. PMID 29849139 DOI: 10.1038/S41586-018-0187-Y |
0.673 |
|
2018 |
Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates. Elife. 7. PMID 29745899 DOI: 10.7554/Elife.36620 |
0.497 |
|
2018 |
Mihaylova MM, Cheng CW, Cao AQ, Tripathi S, Mana MD, Bauer-Rowe KE, Abu-Remaileh M, Clavain L, Erdemir A, Lewis CA, Freinkman E, Dickey AS, La Spada AR, Huang Y, Bell GW, et al. Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Cell Stem Cell. 22: 769-778.e4. PMID 29727683 DOI: 10.1016/J.Stem.2018.04.001 |
0.651 |
|
2018 |
Wyant GA, Abu-Remaileh M, Frenkel EM, Laqtom NN, Dharamdasani V, Lewis CA, Chan SH, Heinze I, Ori A, Sabatini DM. NUFIP1 is a ribosome receptor for starvation-induced ribophagy. Science (New York, N.Y.). PMID 29700228 DOI: 10.1126/Science.Aar2663 |
0.54 |
|
2018 |
Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Author response: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates Elife. DOI: 10.7554/Elife.36620.020 |
0.482 |
|
2017 |
Abu-Remaileh M, Wyant GA, Kim C, Laqtom NN, Abbasi M, Chan SH, Freinkman E, Sabatini DM. Lysosomal metabolomics reveals V-ATPase and mTOR-dependent regulation of amino acid efflux from lysosomes. Science (New York, N.Y.). PMID 29074583 DOI: 10.1126/Science.Aan6298 |
0.547 |
|
2017 |
Wyant GA, Abu-Remaileh M, Wolfson RL, Chen WW, Freinkman E, Danai LV, Vander Heiden MG, Sabatini DM. mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient. Cell. 171: 642-654.e12. PMID 29053970 DOI: 10.1016/J.Cell.2017.09.046 |
0.552 |
|
2017 |
Cantor JR, Abu-Remaileh M, Kanarek N, Freinkman E, Gao X, Louissaint A, Lewis CA, Sabatini DM. Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase. Cell. 169: 258-272.e17. PMID 28388410 DOI: 10.1016/J.Cell.2017.03.023 |
0.539 |
|
2017 |
Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. PMID 28199306 DOI: 10.1038/Nature21423 |
0.66 |
|
2017 |
Kanarek N, Freinkman E, Cantor J, Abu-Remaileh M, Wang T, Sabatini DM. Abstract 4988: Genome-wide CRISPR screen and metabolite profiling reveal a new mechanism of methotrexate sensitivity Cancer Research. 77: 4988-4988. DOI: 10.1158/1538-7445.Am2017-4988 |
0.557 |
|
2016 |
Pacold ME, Brimacombe KR, Chan SH, Rohde JM, Lewis CA, Swier LJ, Possemato R, Chen WW, Sullivan LB, Fiske BP, Cho S, Freinkman E, Birsoy K, Abu-Remaileh M, Shaul YD, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nature Chemical Biology. PMID 27110680 DOI: 10.1038/Nchembio.2070 |
0.722 |
|
2016 |
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. 531: 53-8. PMID 26935695 DOI: 10.1038/Nature17173 |
0.713 |
|
2016 |
Aran D, Abu-Remaileh M, Levy R, Meron N, Toperoff G, Edrei Y, Bergman Y, Hellman A. Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer. Plos Genetics. 12: e1005840. PMID 26886256 DOI: 10.1371/Journal.Pgen.1005840 |
0.625 |
|
2016 |
Aran D, Abu-Remaileh M, Levy R, Meron N, Toperoff G, Edrei Y, Bergman Y, Hellman A. Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer Plos Genetics. 12. DOI: 10.1371/journal.pgen.1005840 |
0.572 |
|
2015 |
Birsoy K, Wang T, Chen WW, Freinkman E, Abu-Remaileh M, Sabatini DM. An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis. Cell. 162: 540-551. PMID 26232224 DOI: 10.1016/J.Cell.2015.07.016 |
0.699 |
|
2015 |
Abu-Remaileh M, Bender S, Raddatz G, Ansari I, Cohen D, Gutekunst J, Musch T, Linhart H, Breiling A, Pikarsky E, Bergman Y, Lyko F. Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer. Cancer Research. 75: 2120-30. PMID 25808873 DOI: 10.1158/0008-5472.Can-14-3295 |
0.602 |
|
2014 |
Ludwig G, Nejman D, Hecht M, Orlanski S, Abu-Remaileh M, Yanuka O, Sandler O, Marx A, Roberts D, Benvenisty N, Bergman Y, Mendelsohn M, Cedar H. Aberrant DNA methylation in ES cells. Plos One. 9: e96090. PMID 24852222 DOI: 10.1371/Journal.Pone.0096090 |
0.617 |
|
2010 |
Abu-Remaileh M, Gerson A, Farago M, Nathan G, Alkalay I, Zins Rousso S, Gur M, Fainsod A, Bergman Y. Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling. The Embo Journal. 29: 3236-48. PMID 20736927 DOI: 10.1038/Emboj.2010.200 |
0.591 |
|
2008 |
Epsztejn-Litman S, Feldman N, Abu-Remaileh M, Shufaro Y, Gerson A, Ueda J, Deplus R, Fuks F, Shinkai Y, Cedar H, Bergman Y. De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nature Structural & Molecular Biology. 15: 1176-83. PMID 18953337 DOI: 10.1038/Nsmb.1476 |
0.586 |
|
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