Year |
Citation |
Score |
2024 |
Lau K, Kotzur R, Richter F. Blood-brain barrier alterations and their impact on Parkinson's disease pathogenesis and therapy. Translational Neurodegeneration. 13: 37. PMID 39075566 DOI: 10.1186/s40035-024-00430-z |
0.315 |
|
2024 |
Thi Lai T, Kim YE, Nguyen LTN, Thi Nguyen T, Kwak IH, Richter F, Kim YJ, Ma HI. Microglial inhibition alleviates alpha-synuclein propagation and neurodegeneration in Parkinson's disease mouse model. Npj Parkinson's Disease. 10: 32. PMID 38302446 DOI: 10.1038/s41531-024-00640-2 |
0.381 |
|
2023 |
Lau K, Porschen LT, Richter F, Gericke B. Microvascular blood-brain barrier alterations in isolated brain capillaries of mice over-expressing alpha-synuclein (Thy1-aSyn line 61). Neurobiology of Disease. 187: 106298. PMID 37716515 DOI: 10.1016/j.nbd.2023.106298 |
0.371 |
|
2023 |
Lai TT, Gericke B, Feja M, Conoscenti M, Zelikowsky M, Richter F. Anxiety in synucleinopathies: neuronal circuitry, underlying pathomechanisms and current therapeutic strategies. Npj Parkinson's Disease. 9: 97. PMID 37349373 DOI: 10.1038/s41531-023-00547-4 |
0.324 |
|
2023 |
Schidlitzki A, Stanojlovic M, Fournier C, Käufer C, Feja M, Gericke B, Garzotti M, Welford RWD, Steiner MA, Angot E, Richter F. Double-Edged Effects of Venglustat on Behavior and Pathology in Mice Overexpressing α-Synuclein. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 37050861 DOI: 10.1002/mds.29398 |
0.357 |
|
2023 |
Richter F, Stanojlovic M, Käufer C, Gericke B, Feja M. A Mouse Model to Test Novel Therapeutics for Parkinson's Disease: an Update on the Thy1-aSyn ("line 61") Mice. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 36715870 DOI: 10.1007/s13311-022-01338-0 |
0.389 |
|
2022 |
Schulz A, Richter F, Richter A. In vivo optogenetic inhibition of striatal parvalbumin-reactive interneurons induced genotype-specific changes in neuronal activity without dystonic signs in male DYT1 knock-in mice. Journal of Neuroscience Research. PMID 36546658 DOI: 10.1002/jnr.25157 |
0.393 |
|
2022 |
Bluhm A, Schrempel S, Moceri S, Stieler J, Feja M, Schilling S, Schulze A, von Hörsten S, Hartlage-Rübsamen M, Richter F, Roßner S. Alpha synuclein processing by MMP-3 - implications for synucleinopathies. Behavioural Brain Research. 434: 114020. PMID 35870616 DOI: 10.1016/j.bbr.2022.114020 |
0.334 |
|
2021 |
Torres ERS, Stanojlovic M, Zelikowsky M, Bonsberger J, Hean S, Mulligan C, Baldauf L, Fleming S, Masliah E, Chesselet MF, Fanselow MS, Richter F. Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease. Neurobiology of Disease. 158: 105478. PMID 34390837 DOI: 10.1016/j.nbd.2021.105478 |
0.646 |
|
2021 |
Bender H, Fietz SA, Richter F, Stanojlovic M. Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult Hippocampus. Frontiers in Cell and Developmental Biology. 9: 691560. PMID 34307368 DOI: 10.3389/fcell.2021.691560 |
0.429 |
|
2020 |
Wildburger NC, Hartke AS, Schidlitzki A, Richter F. Current Evidence for a Bidirectional Loop Between the Lysosome and Alpha-Synuclein Proteoforms. Frontiers in Cell and Developmental Biology. 8: 598446. PMID 33282874 DOI: 10.3389/fcell.2020.598446 |
0.328 |
|
2020 |
Perl S, Richter F, Richter A. Striatal and cortical metabotropic glutamate 5 receptor expression and behavioral effects of the positive allosteric modulator CDPPB in a model of DYT1 dystonia. Pharmacology, Biochemistry, and Behavior. 172977. PMID 32615137 DOI: 10.1016/J.Pbb.2020.172977 |
0.414 |
|
2019 |
Richter F, Klein L, Helmschrodt C, Richter A. Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia. Plos One. 14: e0226080. PMID 31805123 DOI: 10.1371/Journal.Pone.0226080 |
0.374 |
|
2019 |
Zhong H, Zhu C, Minegishi Y, Richter F, Zdunowski S, Roy RR, Vissel B, Gad P, Gerasimenko Y, Chesselet MF, Edgerton VR. Epidural Spinal Cord Stimulation Improves Motor Function in Rats With Chemically Induced Parkinsonism. Neurorehabilitation and Neural Repair. 1545968319876891. PMID 31684831 DOI: 10.1177/1545968319876891 |
0.506 |
|
2019 |
Perl S, Richter F, Gericke B, Richter A. Expression of metabotropic glutamate 5 receptors in the striatum and cortex and effects of modulators on the severity of dystonia in the phenotypic dt model. European Journal of Pharmacology. 859: 172527. PMID 31283933 DOI: 10.1016/J.Ejphar.2019.172527 |
0.326 |
|
2019 |
Richter F, Bauer A, Perl S, Schulz A, Richter A. Optogenetic augmentation of the hypercholinergic endophenotype in DYT1 knock-in mice induced erratic hyperactive movements but not dystonia. Ebiomedicine. PMID 30819512 DOI: 10.1016/J.Ebiom.2019.02.042 |
0.368 |
|
2018 |
Landmann J, Richter F, Classen J, Richter A, Penninger JM, Bechmann I. Behavioral phenotyping of calcium channel (CACN) subunit α2δ3 knockout mice: Consequences of sensory cross-modal activation. Behavioural Brain Research. PMID 29305318 DOI: 10.1016/J.Bbr.2017.12.032 |
0.387 |
|
2017 |
Helmschrodt C, Höbel S, Schöniger S, Bauer A, Bonicelli J, Gringmuth M, Fietz SA, Aigner A, Richter A, Richter F. Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson's Disease. Molecular Therapy. Nucleic Acids. 9: 57-68. PMID 29246324 DOI: 10.1016/J.Omtn.2017.08.013 |
0.441 |
|
2017 |
Landmann J, Richter F, Oros-Peusquens AM, Shah NJ, Classen J, Neely GG, Richter A, Penninger JM, Bechmann I. Neuroanatomy of pain-deficiency and cross-modal activation in calcium channel subunit (CACN) α2δ3 knockout mice. Brain Structure & Function. PMID 28733833 DOI: 10.1007/S00429-017-1473-4 |
0.399 |
|
2017 |
Richter F, Subramaniam SR, Magen I, Lee P, Hayes J, Attar A, Zhu C, Franich NR, Bove N, De La Rosa K, Kwong J, Klärner FG, Schrader T, Chesselet MF, Bitan G. A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28585223 DOI: 10.1007/S13311-017-0544-9 |
0.633 |
|
2017 |
Bauer A, Gerstenberger J, Gringmuth M, Richter F, Richter A. P 77 Optogenetic stimulations of striatal cholinergic interneurons in an animal model of dystonia Clinical Neurophysiology. 128. DOI: 10.1016/J.Clinph.2017.06.153 |
0.458 |
|
2017 |
Richter F, Bode C, Spröte C, Brigadski T, Bauer A, Fietz S, Fritschy J, Richter A. P 76 Maturation deficits in striatal interneurons in a phenotypic model of dystonia Clinical Neurophysiology. 128: e365-e366. DOI: 10.1016/J.Clinph.2017.06.152 |
0.429 |
|
2016 |
Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice. Neurobiology of Aging. 51: 54-66. PMID 28038352 DOI: 10.1016/J.Neurobiolaging.2016.11.015 |
0.648 |
|
2016 |
Bode C, Richter F, Spröte C, Brigadski T, Bauer A, Fietz S, Fritschy JM, Richter A. Altered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia. Experimental Neurology. PMID 27780732 DOI: 10.1016/J.Expneurol.2016.10.013 |
0.407 |
|
2016 |
Richter F, Gerstenberger J, Bauer A, Liang CC, Richter A. Sensorimotor tests unmask a phenotype in the DYT1 knock-in mouse model of dystonia. Behavioural Brain Research. 317: 536-541. PMID 27769743 DOI: 10.1016/J.Bbr.2016.10.028 |
0.459 |
|
2016 |
Spröte C, Richter F, Bauer A, Gerstenberger J, Richter A. The α2β3γ2 GABAA receptor preferring agonist NS11394 aggravates dystonia in the phenotypic dt(sz) model. European Journal of Pharmacology. PMID 27693801 DOI: 10.1016/J.Ejphar.2016.09.040 |
0.308 |
|
2016 |
Gerstenberger J, Bauer A, Helmschrodt C, Richter A, Richter F. The novel adaptive rotating beam test unmasks sensorimotor impairments in a transgenic mouse model of Parkinson's disease. Behavioural Brain Research. PMID 26880341 DOI: 10.1016/J.Bbr.2016.02.017 |
0.524 |
|
2014 |
Magen I, Ostritsky R, Richter F, Zhu C, Fleming SM, Lemesre V, Stewart AJ, Morimoto BH, Gozes I, Chesselet MF. Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein. Pharmacology Research & Perspectives. 2: e00065. PMID 25505609 DOI: 10.1002/Prp2.65 |
0.635 |
|
2014 |
Richter F, Fleming SM, Watson M, Lemesre V, Pellegrino L, Ranes B, Zhu C, Mortazavi F, Mulligan CK, Sioshansi PC, Hean S, De La Rosa K, Khanna R, Flanagan J, Lockhart DJ, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 840-56. PMID 25037721 DOI: 10.1007/S13311-014-0294-X |
0.651 |
|
2014 |
Richter F, Richter A. Genetic animal models of dystonia: common features and diversities. Progress in Neurobiology. 121: 91-113. PMID 25034123 DOI: 10.1016/J.Pneurobio.2014.07.002 |
0.335 |
|
2014 |
Richter F, Gao F, Medvedeva V, Lee P, Bove N, Fleming SM, Michaud M, Lemesre V, Patassini S, De La Rosa K, Mulligan CK, Sioshansi PC, Zhu C, Coppola G, Bordet T, et al. Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons. Neurobiology of Disease. 69: 263-75. PMID 24844147 DOI: 10.1016/J.Nbd.2014.05.012 |
0.696 |
|
2014 |
Grant LM, Richter F, Miller JE, White SA, Fox CM, Zhu C, Chesselet MF, Ciucci MR. Vocalization deficits in mice over-expressing alpha-synuclein, a model of pre-manifest Parkinson's disease. Behavioral Neuroscience. 128: 110-21. PMID 24773432 DOI: 10.1037/A0035965 |
0.692 |
|
2013 |
Chesselet MF, Richter F, Gao F, Fleming SM, Michaud M, Zhu C, Coppola G, Bordet T, Pruss R. Mitochondria-Targeted Cholesterol Oximes Increase Dopamine-Related Gene Expression and Behavior in Mice Over-Expressing Alpha-Synuclein, a Model of Pre-Manifest Parkinson's Disease Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 128. DOI: 10.1016/B978-0-12-800044-1.00112-4 |
0.599 |
|
2012 |
Wang L, Magen I, Yuan PQ, Subramaniam SR, Richter F, Chesselet MF, Taché Y. Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: e425-36. PMID 22779732 DOI: 10.1111/J.1365-2982.2012.01974.X |
0.687 |
|
2012 |
Watson MB, Richter F, Lee SK, Gabby L, Wu J, Masliah E, Effros RB, Chesselet MF. Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein. Experimental Neurology. 237: 318-34. PMID 22750327 DOI: 10.1016/J.Expneurol.2012.06.025 |
0.642 |
|
2012 |
Chesselet MF, Richter F, Zhu C, Magen I, Watson MB, Subramaniam SR. A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 297-314. PMID 22350713 DOI: 10.1007/S13311-012-0104-2 |
0.638 |
|
2012 |
Wang L, Magen I, Richter F, Yuan P, Chesselet M, Tache Y. Tu1972 Mice Overexpressing Wild-Type Human Alpha-Synuclein Display Alterations in Colonic Myenteric Ganglia and Propulsive Colonic Motor Function Gastroenterology. 142: S-889-S-890. DOI: 10.1016/S0016-5085(12)63459-3 |
0.616 |
|
2011 |
Cabeza-Arvelaiz Y, Fleming SM, Richter F, Masliah E, Chesselet MF, Schiestl RH. Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Molecular Neurodegeneration. 6: 83. PMID 22165993 DOI: 10.1186/1750-1326-6-83 |
0.685 |
|
2011 |
Chesselet MF, Richter F. Modelling of Parkinson's disease in mice. The Lancet. Neurology. 10: 1108-18. PMID 22094131 DOI: 10.1016/S1474-4422(11)70227-7 |
0.577 |
|
2011 |
Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein. Journal of Neuroscience Research. 89: 1091-102. PMID 21488084 DOI: 10.1002/Jnr.22611 |
0.644 |
|
2011 |
Fleming SM, Mulligan CK, Richter F, Mortazavi F, Lemesre V, Frias C, Zhu C, Stewart A, Gozes I, Morimoto B, Chesselet MF. A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions. Molecular and Cellular Neurosciences. 46: 597-606. PMID 21193046 DOI: 10.1016/J.Mcn.2010.12.011 |
0.669 |
|
2009 |
Richter F, Meurers BH, Zhu C, Medvedeva VP, Chesselet MF. Neurons express hemoglobin alpha- and beta-chains in rat and human brains. The Journal of Comparative Neurology. 515: 538-47. PMID 19479992 DOI: 10.1002/Cne.22062 |
0.579 |
|
2009 |
Meurers BH, Zhu C, Fernagut PO, Richter F, Hsia YC, Fleming SM, Oh M, Elashoff D, Dicarlo CD, Seaman RL, Chesselet MF. Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo. Neurobiology of Disease. 33: 182-92. PMID 19013527 DOI: 10.1016/J.Nbd.2008.10.001 |
0.588 |
|
2009 |
Richter F, Mulligan C, DeLaRosa K, Sioshansi P, Chesselet M. P2.019 Dopamine transporter knock-down in mice results in loss of nigral dopaminergic neurons and alters the effects of pesticide exposure Parkinsonism & Related Disorders. 15: S93. DOI: 10.1016/S1353-8020(09)70370-0 |
0.337 |
|
2008 |
Richter F, Hamann M, Richter A. Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice. Brain Research. 1188: 148-56. PMID 18035334 DOI: 10.1016/j.brainres.2007.09.083 |
0.438 |
|
2007 |
Richter F, Hamann M, Richter A. Chronic rotenone treatment induces behavioral effects but no pathological signs of parkinsonism in mice. Journal of Neuroscience Research. 85: 681-91. PMID 17171705 DOI: 10.1002/jnr.21159 |
0.464 |
|
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