Amy Beebe - Publications

Affiliations: 
Merck & Co. 

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Guelen L, Fischmann TO, Wong J, Mauze S, Guadagnoli M, Bąbała N, Wagenaars J, Juan V, Rosen D, Prosise W, Habraken M, Lodewijks I, Gu D, Stammen-Vogelzangs J, Yu Y, ... ... Beebe AM, et al. Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy. Journal For Immunotherapy of Cancer. 10. PMID 36100308 DOI: 10.1136/jitc-2022-005049  0.411
2017 Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, ... ... Beebe AM, et al. Characterization of MK-4166, a clinical agonistic antibody that targets human GITR and inhibits the generation and suppressive effects of T regulatory cells. Cancer Research. PMID 28611044 DOI: 10.1158/0008-5472.Can-16-1439  0.491
2016 Mahne A, Mauze S, Joyce-Shaikh B, Xia J, Bowman E, Beebe A, Cua D, Jain R. Dual roles for regulatory T cell depletion and co-stimulatory signaling in agonistic GITR targeting for tumor immunotherapy. Cancer Research. PMID 28122327 DOI: 10.1158/0008-5472.CAN-16-0797  0.367
2015 Brunn ND, Mauze S, Gu D, Wiswell D, Ueda R, Hodges D, Beebe AM, Zhang S, Escandon E. The Role of Anti-drug Antibodies in the Pharmacokinetics, Disposition, Target Engagement, and Efficacy of a GITR Agonist Monoclonal Antibody in Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26669426 DOI: 10.1124/jpet.115.229864  0.458
2015 Ovacik AM, Shinsky-Bjorde N, Hodges D, Antonenko S, Ueda R, Mauze S, Gu D, Wiswell D, Zhang S, Beebe A, Tabrizi M. Abstract 4521: Evaluation of the relationship between serum exposure, receptor (GITR) availability and tumor suppression following administration of the anti-GITR antibody DX400 in mouse syngeneic tumor models Cancer Research. 75: 4521-4521. DOI: 10.1158/1538-7445.Am2015-4521  0.451
2014 Murphy JT, Burey AP, Beebe AM, Gu D, Presta LG, Merghoub T, Wolchok JD. Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice Blood. 123: 2172-2180. PMID 24558202 DOI: 10.1182/Blood-2013-12-544742  0.414
2011 Mumm JB, Emmerich J, Zhang X, Chan I, Wu L, Mauze S, Blaisdell S, Basham B, Dai J, Grein J, Sheppard C, Hong K, Cutler C, Turner S, LaFace D, ... ... Beebe AM, et al. IL-10 elicits IFNγ-dependent tumor immune surveillance. Cancer Cell. 20: 781-96. PMID 22172723 DOI: 10.1016/j.ccr.2011.11.003  0.496
2002 Beebe AM, Cua DJ, de Waal Malefyt R. The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS). Cytokine & Growth Factor Reviews. 13: 403-12. PMID 12220553  0.334
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