James F. Amatruda - Publications

Affiliations: 
Pediatrics University of Southern California, Los Angeles, CA, United States 

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Year Citation  Score
2024 Tiburcio PDB, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Xu L, Chen KS. DROSHA regulates mesenchymal gene expression in Wilms tumor. Molecular Cancer Research : McR. PMID 38647377 DOI: 10.1158/1541-7786.MCR-23-0930  0.34
2023 Kuo C, Amatruda JF. Seed becoming soil: A new paradigm of the Ewing sarcoma tumor microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37796143 DOI: 10.1158/1078-0432.CCR-23-2259  0.305
2023 Xu L, Pierce JL, Sanchez A, Chen KS, Shukla AA, Fustino NJ, Stuart SH, Bagrodia A, Xiao X, Guo L, Krailo MD, Shaikh F, Billmire DF, Pashankar F, Bestrashniy J, ... ... Amatruda JF, et al. Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence. Nature Communications. 14: 2636. PMID 37149691 DOI: 10.1038/s41467-023-38378-9  0.318
2023 Xu L, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhang Y, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Chen KS. Wilms tumor mutational subclasses converge to drive overexpression. Medrxiv : the Preprint Server For Health Sciences. PMID 36778325 DOI: 10.1101/2023.01.30.23285117  0.308
2023 Watson S, LaVigne CA, Xu L, Surdez D, Cyrta J, Calderon D, Cannon MV, Kent MR, Silvius KM, Kucinski JP, Harrison EN, Murchison W, Rakheja D, Tirode F, Delattre O, ... Amatruda JF, et al. VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis. Cell Reports. 42: 112013. PMID 36656711 DOI: 10.1016/j.celrep.2023.112013  0.302
2022 Vasileva E, Warren M, Triche TJ, Amatruda JF. Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth. Elife. 11. PMID 35285802 DOI: 10.7554/eLife.69734  0.345
2021 Ci B, Lin SY, Yao B, Luo D, Xu L, Krailo M, Murray MJ, Amatruda JF, Frazier AL, Xie Y. Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. Methods in Molecular Biology (Clifton, N.J.). 2195: 263-275. PMID 32852769 DOI: 10.1007/978-1-0716-0860-9_17  0.344
2020 Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, ... ... Amatruda JF, et al. Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. Nature Communications. 11: 2423. PMID 32415069 DOI: 10.1038/S41467-020-16244-2  0.309
2020 Wiemels JL, Wang R, Feng Q, Clark CJ, Amatruda JF, Rubin E, Yee A, Morimoto LM, Metayer C, Ma X. Birth characteristics and risk of early-onset synovial sarcoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32245786 DOI: 10.1158/1055-9965.Epi-20-0093  0.305
2020 Chen KS, Desai K, Amatruda JF. Abstract PR01: Three-hit model of Wilms’ tumor formation reveals immunogenic transcriptional subtypes Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-Pr01  0.386
2020 Su XA, Ma D, Parsons JV, Replogle JM, Amatruda JF, Whittaker CA, Stegmaier K, Amon A. Abstract B52: Ewing sarcoma: A case study of clonal aneuploidy and DNA damage repair in pediatric cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B52  0.376
2020 Segal D, Chang B, Mazloom-Farsibaf H, Fiolka R, Amatruda J, Danuser G. Abstract PHB01: The zebrafish as a mechanical filter: Using zebrafish xenografts to model Ewing sarcoma metastasis in vivo Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Phb01  0.385
2019 Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, et al. GCNA Preserves Genome Integrity and Fertility Across Species. Developmental Cell. PMID 31839537 DOI: 10.1016/J.Devcel.2019.11.007  0.334
2019 Lafin JT, Singla N, Woldu SL, Lotan Y, Lewis CM, Majmudar K, Savelyeva A, Kapur P, Margulis V, Strand DW, Murray MJ, Amatruda JF, Bagrodia A. Serum MicroRNA-371a-3p Levels Predict Viable Germ Cell Tumor in Chemotherapy-naïve Patients Undergoing Retroperitoneal Lymph Node Dissection. European Urology. PMID 31699528 DOI: 10.1200/Jco.2020.38.6_Suppl.417  0.349
2019 Sanchez A, Xu L, Pierce JL, Lafin JT, Abe D, Bagrodia A, Frazier AL, Amatruda JF. Identification of testicular cancer driver genes by a cross-species comparative oncology approach. Andrology. PMID 31087453 DOI: 10.1111/Andr.12644  0.467
2019 Singla N, Lafin JT, Ghandour RA, Kaffenberger S, Amatruda JF, Bagrodia A. Genetics of testicular germ cell tumors. Current Opinion in Urology. PMID 31045925 DOI: 10.1097/Mou.0000000000000642  0.385
2019 Lafin JT, Bagrodia A, Woldu S, Amatruda JF. New insights into germ cell tumor genomics Journal of Andrology. 7: 507-515. PMID 30896089 DOI: 10.1111/Andr.12616  0.423
2019 Singla S, Wong J, Singla N, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda J, Lindsay Frazier A, Bagrodia A. Clinicopathologic predictors of outcomes in children with stage I germ cell tumours: A pooled post hoc analysis of trials from the Children’s Oncology Group European Urology Supplements. 18: 17-18. DOI: 10.1200/Jco.2020.38.6_Suppl.418  0.357
2019 O'Neill AF, Xia C, Krailo MD, Shaikh F, Pashankar FD, Billmire DF, Olson TA, Amatruda JF, Villaluna D, Malogolowkin MH, Rodriguez-Galindo C, Frazier AL. Alfa-feto protein (AFP) as a predictor of outcome for children with germ cell tumors: A report from the malignant germ cell international consortium. Journal of Clinical Oncology. 37: 10036-10036. DOI: 10.1200/Jco.2019.37.15_Suppl.10036  0.447
2019 Shaikh F, Stark DP, Dang H, Xia C, Krailo MD, Stenning SP, Pashankar FD, Rodriguez-Galindo C, Olson TA, Hale J, Depani S, Stoneham S, Nicholson J, Murray M, Amatruda JF, et al. Outcomes of adolescent males with extracranial malignant germ cell tumors compared with children and young adults: A report from the Malignant Germ Cell Tumors International Consortium (MaGIC) group. Journal of Clinical Oncology. 37: 10022-10022. DOI: 10.1200/Jco.2019.37.15_Suppl.10022  0.421
2019 Kendall GC, Watson S, Xu L, LaVigne C, Murchison W, Rakheja D, Tirode F, Delattre O, Amatruda J. Abstract 872: Genetic models reveal that the novelVGLL2-NCOA2fusion oncogene leverages embryonic programs for sarcomagenesis Cancer Research. 79: 872-872. DOI: 10.1158/1538-7445.Sabcs18-872  0.443
2018 Fonseca A, Xia C, Lorenzo AJ, Krailo M, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Billmire DF, Rodriguez-Galindo C, Frazier AL, Shaikh F. Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1800790. PMID 30576269 DOI: 10.1200/Jco.18.00790  0.396
2018 Williams LA, Pankratz N, Lane J, Krailo M, Roesler M, Richardson M, Lindsay Frazier A, Amatruda JF, Poynter JN. Klinefelter syndrome in males with germ cell tumors: A report from the children's oncology group. Cancer. PMID 30291793 DOI: 10.1002/Cncr.31667  0.368
2018 Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF. Mutations in microRNA processing genes in Wilms tumors derepress the regulator . Genes & Development. PMID 30026293 DOI: 10.1101/Gad.313783.118  0.422
2018 Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX. Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes. Cell Reports. 24: 238-251. PMID 29972784 DOI: 10.1016/J.Celrep.2018.06.006  0.357
2018 Shah R, Xia C, Krailo M, Amatruda JF, Arul SG, Billmire DF, Brady WE, Covens A, Gershenson DM, Hale JP, Hurteau J, Murray MJ, Nicholson JC, Olson TA, Pashankar F, et al. Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecologic Oncology. PMID 29884437 DOI: 10.1016/J.Ygyno.2018.05.025  0.344
2018 Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. transgenic zebrafish models identify as a mediator of rhabdomyosarcoma tumorigenesis. Elife. 7. PMID 29869612 DOI: 10.7554/Elife.33800  0.43
2018 Frazier AL, Stoneham S, Rodriguez-Galindo C, Dang H, Xia C, Olson TA, Murray MJ, Amatruda JF, Shaikh F, Pashankar F, Billmire D, Krailo M, Stark D, Brougham MFH, Nicholson JC, et al. Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium. European Journal of Cancer (Oxford, England : 1990). 98: 30-37. PMID 29859339 DOI: 10.1016/J.Ejca.2018.03.004  0.349
2018 Pierce JL, Frazier AL, Amatruda JF. Pediatric Germ Cell Tumors: A Developmental Perspective. Advances in Urology. 2018: 9059382. PMID 29515628 DOI: 10.1155/2018/9059382  0.429
2018 Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF. EGF Receptor and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors. Molecular Cancer Therapeutics. PMID 29483210 DOI: 10.1158/1535-7163.Mct-17-0137  0.433
2018 Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, et al. Adolescents and Young Adults With a "Rare" Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors. The Oncologist. 23: 272. PMID 29449513 DOI: 10.1634/Theoncologist.2014-0009Erratum  0.36
2018 Watson S, Kendall GC, Murchison WA, Delattre O, Tirode F, Amatruda JF. Abstract PR06: Functional genomics of CIC-DUX4 fusions in zebrafish recapitulates the spectrum of human CIC-rearranged cancers Omics a Journal of Integrative Biology. 24. DOI: 10.1158/1557-3265.Sarcomas17-Pr06  0.461
2018 Williams LA, Pankratz N, Lane J, Roesler M, Richardson M, Frazier AL, Amatruda J, Poynter JN. Abstract A25: Prevalence of Klinefelter syndrome among males aged 0-19 years diagnosed with germ cell tumors: A report from the Children’s Oncology Group Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-A25  0.321
2018 Williams LA, Mills L, Hooten AJ, Langer E, Roesler M, Frazier AL, Amatruda J, Poynter JN. Abstract 2064: Differences in methylation patterns by pediatric germ cell tumor histologic subtype Cancer Research. 78: 2064-2064. DOI: 10.1158/1538-7445.Am2018-2064  0.397
2017 Dicken BJ, Billmire DF, Krailo M, Xia C, Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Rescorla FJ, Egler RA, Ross JH, Rodriguez-Galindo C, Frazier AL. Gonadal dysgenesis is associated with worse outcomes in patients with ovarian nondysgerminomatous tumors: A report of the Children's Oncology Group AGCT 0132 study. Pediatric Blood & Cancer. PMID 29286555 DOI: 10.1002/Pbc.26913  0.41
2017 Woldu SL, Aydin AM, Rao AV, Hutchinson RC, Singla N, Clinton TN, Krabbe LM, Passoni NM, Raj GV, Miller DS, Amatruda JF, Sagalowsky AI, Lotan Y, Arriaga Y, Margulis V, et al. Differences at Presentation and Treatment of Testicular Cancer in Hispanic Men: Institutional and National Hospital-Based Analysis. Urology. PMID 29079210 DOI: 10.1016/J.Urology.2017.08.059  0.344
2017 Tiwari B, Kurtz P, Jones AE, Wylie A, Amatruda JF, Boggupalli DP, Gonsalvez GB, Abrams JM. Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. Current Biology : Cb. PMID 28966088 DOI: 10.1016/J.Cub.2017.08.036  0.318
2017 Marcotte EL, Pankratz N, Amatruda JF, Frazier AL, Krailo M, Davies S, Starr JR, Ching CL, Roesler M, Langer E, Hallstrom C, Hooten AJ, Poynter JN. Variants in BAK1, SPRY4, and GAB2 are Associated with Pediatric Germ Cell Tumors: A Report from the Children's Oncology Group. Genes, Chromosomes & Cancer. PMID 28295819 DOI: 10.1002/Gcc.22457  0.301
2017 Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Villaluna D, Krailo M, Billmire DF, Rescorla FJ, Egler RA, Dicken BJ, Ross JH, Schlatter M, Rodriguez-Galindo C, et al. Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016676544. PMID 28240974 DOI: 10.1200/Jco.2016.67.6544  0.354
2017 Gardiner JD, Abegglen LM, Huang X, Carter BE, Schackmann EA, Stucki M, Paxton CN, Randall RL, Amatruda JF, Putnam AR, Kovar H, Lessnick SL, Schiffman JD. C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells. Oncotarget. PMID 28148901 DOI: 10.18632/Oncotarget.14847  0.326
2017 Woldu SL, Amatruda JF, Bagrodia A. Testicular germ cell tumor genomics. Current Opinion in Urology. 27: 41-47. PMID 27584029 DOI: 10.1097/Mou.0000000000000347  0.38
2017 Gardiner JD, Huang X, Lazaris E, Jones K, Yap JT, Randall RL, Abegglen L, Amatruda J, Schiffman JD. Association of genomically unstable Ewing sarcoma tumors with HOTAIR overexpression and clinical outcome. Journal of Clinical Oncology. 35: 11035-11035. DOI: 10.1200/Jco.2017.35.15_Suppl.11035  0.372
2016 Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nature Medicine. PMID 27941793 DOI: 10.1038/Nm.4252  0.382
2016 Liao Z, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. Risk of Second Malignant Neoplasms in Women and Girls with Germ Cell Tumors. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 27864217 DOI: 10.1093/Annonc/Mdw609  0.308
2016 Lee E, Wei Y, Zou Z, Tucker K, Rakheja D, Levine B, Amatruda JF. Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis. Oncotarget. PMID 27655644 DOI: 10.18632/Oncotarget.12084  0.437
2016 Dranow DB, Hu K, Bird AM, Lawry ST, Adams MT, Sanchez A, Amatruda JF, Draper BW. Bmp15 Is an Oocyte-Produced Signal Required for Maintenance of the Adult Female Sexual Phenotype in Zebrafish. Plos Genetics. 12: e1006323. PMID 27642754 DOI: 10.1371/Journal.Pgen.1006323  0.301
2016 Kendall GC, Amatruda JF. Zebrafish as a Model for the Study of Solid Malignancies. Methods in Molecular Biology (Clifton, N.J.). 1451: 121-42. PMID 27464805 DOI: 10.1007/978-1-4939-3771-4_9  0.433
2016 Shaikh F, Murray MJ, Amatruda JF, Coleman N, Nicholson JC, Hale JP, Pashankar F, Stoneham SJ, Poynter JN, Olson TA, Billmire DF, Stark D, Rodriguez-Galindo C, Frazier AL. Paediatric extracranial germ-cell tumours. The Lancet. Oncology. 17: e149-e162. PMID 27300675 DOI: 10.1016/S1470-2045(15)00545-8  0.331
2016 Sanchez A, Amatruda JF. Zebrafish Germ Cell Tumors. Advances in Experimental Medicine and Biology. 916: 479-94. PMID 27165367 DOI: 10.1007/978-3-319-30654-4_21  0.479
2016 Liao ZW, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. Risk of second gonadal cancers in women and children with germ cell tumors. Cancer. PMID 27152727 DOI: 10.1002/Cncr.30014  0.362
2016 Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, et al. The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease. Oncotarget. PMID 26802024 DOI: 10.18632/Oncotarget.6937  0.374
2016 Wylie A, Jones AE, D'Brot A, Lu WJ, Kurtz P, Moran JV, Rakheja D, Chen KS, Hammer RE, Comerford SA, Amatruda JF, Abrams JM. p53 genes function to restrain mobile elements. Genes & Development. 30: 64-77. PMID 26701264 DOI: 10.1101/Gad.266098.115  0.314
2016 Meade JC, Moore ZR, Stuart SH, Cholka A, Boriack RL, Xu J, Erdreich-Epstein A, Rakheja D, Boothman DA, Amatruda JF, Laetsch TW. Abstract B39: NQO1 as a therapeutic target for atypical teratoid/ rhabdoid tumor Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B39  0.415
2016 Budhipramono A, Rakheja D, Chen KS, Fustino N, Shukla A, Wickiser J, Laetsch T, Amatruda JF. Abstract B03: EGFR and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-B03  0.403
2016 Chen KS, Rakheja D, Liu Y, Shukla AA, Mendell JT, Amatruda JF. Abstract IA12: Mechanisms of tumorigenesis due to somatic mutations in DICER1 and DROSHA in childhood kidney cancers Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Ia12  0.372
2016 Kendall G, Watson S, Xu L, Tirode F, Delattre O, Amatruda J. Abstract NG03: Zebrafish models of PAX3-FOXO1 pathogenesis reveal novel targets in human rhabdomyosarcoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ng03  0.416
2016 Marcotte EL, Pankratz N, Amatruda J, Frazier AL, Krailo M, Davies S, Starr J, Langer E, Hallstrom C, Hooten A, Poynter JN. Abstract LB-374: Variants in BAK1 and SPRY4 are associated with pediatric germ cell tumors Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-374  0.362
2016 Watson S, Kendall G, Delattre O, Tirode F, Amatruda JF. Abstract 4190: Expression of a human CIC-DUX4 fusion is sufficient to induce malignant small round blue cell tumors in zebrafish: a new model of CIC-DUX4 sarcoma for translational research Cancer Research. 76: 4190-4190. DOI: 10.1158/1538-7445.Am2016-4190  0.467
2015 Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, ... Amatruda JF, et al. Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nature Communications. 6: 8891. PMID 26573325 DOI: 10.1038/Ncomms9891  0.364
2015 Pashankar F, Hale JP, Dang H, Krailo M, Brady WE, Rodriguez-Galindo C, Nicholson JC, Murray MJ, Bilmire DF, Stoneham S, Arul GS, Olson TA, Stark D, Shaikh F, Amatruda JF, et al. Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer. PMID 26485622 DOI: 10.1002/Cncr.29732  0.339
2015 Olson TA, Murray MJ, Rodriguez-Galindo C, Nicholson JC, Billmire DF, Krailo MD, Dang HM, Amatruda JF, Thornton CM, Arul GS, Stoneham SJ, Pashankar F, Stark D, Shaikh F, Gershenson DM, et al. Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 3018-28. PMID 26304902 DOI: 10.1200/Jco.2014.60.5337  0.393
2015 Rescorla FJ, Ross JH, Billmire DF, Dicken BJ, Villaluna D, Davis MM, Krailo M, Cullen JW, Olson TA, Egler RA, Amatruda JF, Rodrigues-Galindo C, Frazier AL. Surveillance after initial surgery for Stage I pediatric and adolescent boys with malignant testicular germ cell tumors: Report from the Children's Oncology Group. Journal of Pediatric Surgery. 50: 1000-3. PMID 25812445 DOI: 10.1016/J.Jpedsurg.2015.03.026  0.394
2015 Frazier AL, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray MJ, Amatruda JF, Thornton C, Arul GS, Billmire D, Shaikh F, Pashankar F, Stoneham S, Krailo M, Nicholson JC. Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 195-201. PMID 25452439 DOI: 10.1200/Jco.2014.58.3369  0.404
2015 Moore ZR, Stuart S, Cholka A, Venkataraman A, Xu J, Erdreich-Epstein A, Rakheja D, Boothman DA, Amatruda JF, Laetsch TW. Abstract 1613: β-lapachone: a novel targeted therapy for atypical teratoid rhabdoid tumors (ATRTs) Cancer Research. 75: 1613-1613. DOI: 10.1158/1538-7445.Am2015-1613  0.315
2014 Aloisio GM, Nakada Y, Saatcioglu HD, Peña CG, Baker MD, Tarnawa ED, Mukherjee J, Manjunath H, Bugde A, Sengupta AL, Amatruda JF, Cuevas I, Hamra FK, Castrillon DH. PAX7 expression defines germline stem cells in the adult testis. The Journal of Clinical Investigation. 124: 3929-44. PMID 25133429 DOI: 10.1172/Jci75943  0.345
2014 Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, et al. Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors. The Oncologist. 19: 689-92. PMID 24899644 DOI: 10.1634/Theoncologist.2014-0009  0.412
2014 Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF. Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 10: 572-87. PMID 24441423 DOI: 10.4161/Auto.27649  0.302
2014 Laetsch TW, Kumar K, Rakheja D, Wickiser JE, Rodriguez-Galindo C, Frazier AL, Amatruda J. A phase II study of sirolimus and erlotinib in recurrent/refractory germ cell tumors. Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.Tps2638  0.441
2014 Shaikh F, Dang H, Krailo MD, Hale J, Nicholson J, Rodriguez-Galindo C, Olson TA, Murray M, Amatruda J, Thornton C, Arul S, Billmire D, Frazier AL. Postrecurrence survival for pediatric extracranial malignant germ cell tumors: A report from the Malignant Germ Cell Tumors International Collaborative (MaGIC) Group. Journal of Clinical Oncology. 32: 10074-10074. DOI: 10.1200/Jco.2014.32.15_Suppl.10074  0.385
2014 Rakheja D, Chen KS, Liu Y, Chang T, Shukla AA, Malter J, Mendell JT, Amatruda JF. Abstract LB-204: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis in Wilms tumors Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-A22  0.383
2013 Amatruda JF, Ross JA, Christensen B, Fustino NJ, Chen KS, Hooten AJ, Nelson H, Kuriger JK, Rakheja D, Frazier AL, Poynter JN. DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors. Bmc Cancer. 13: 313. PMID 23806198 DOI: 10.1186/1471-2407-13-313  0.371
2013 Chen KS, Amatruda JF. A big catch for germ cell tumour research. Plos Genetics. 9: e1003481. PMID 23593043 DOI: 10.1371/Journal.Pgen.1003481  0.419
2013 Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G. Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatric Blood & Cancer. 60: 1016-21. PMID 23255219 DOI: 10.1002/Pbc.24428  0.419
2013 Shukla AA, Khokhar S, Amatruda JF, Rakheja D. Abstract 5046: Protein tyrosine phosphatase epsilon (PTPE), a candidate tumor-suppressor in Wilms tumors of childhood, can regulate PI3K/AKT/mTOR pathway. Cancer Research. 73: 5046-5046. DOI: 10.1158/1538-7445.Am2013-5046  0.431
2012 Verduzco D, Dovey JS, Shukla AA, Kodym E, Skaug BA, Amatruda JF. Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development. Molecular Cancer Research : McR. 10: 1451-61. PMID 22986406 DOI: 10.1158/1541-7786.Mcr-12-0072  0.365
2012 Frazier AL, Weldon C, Amatruda J. Fetal and neonatal germ cell tumors. Seminars in Fetal & Neonatal Medicine. 17: 222-230. PMID 22647545 DOI: 10.1016/J.Siny.2012.05.004  0.431
2012 Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, et al. Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. The Journal of Biological Chemistry. 287: 23246-54. PMID 22593577 DOI: 10.1074/Jbc.M112.372029  0.308
2012 Moro E, Ozhan-Kizil G, Mongera A, Beis D, Wierzbicki C, Young RM, Bournele D, Domenichini A, Valdivia LE, Lum L, Chen C, Amatruda JF, Tiso N, Weidinger G, Argenton F. In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Developmental Biology. 366: 327-40. PMID 22546689 DOI: 10.1016/J.Ydbio.2012.03.023  0.332
2012 Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Disease Models & Mechanisms. 5: 95-106. PMID 21979944 DOI: 10.1242/Dmm.007401  0.451
2011 Neumann JC, Lillard K, Damoulis V, Amatruda JF. Zebrafish models of germ cell tumor. Methods in Cell Biology. 105: 3-24. PMID 21951524 DOI: 10.1016/B978-0-12-381320-6.00001-1  0.458
2011 Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga L, Margraf L, Rakheja D, Amatruda JF. Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 108: 13153-8. PMID 21775673 DOI: 10.1073/Pnas.1102311108  0.431
2011 Fustino N, Rakheja D, Ateek CS, Neumann JC, Amatruda JF. Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours. International Journal of Andrology. 34: e218-33. PMID 21696393 DOI: 10.1111/J.1365-2605.2011.01186.X  0.329
2011 Verduzco D, Amatruda JF. Analysis of cell proliferation, senescence, and cell death in zebrafish embryos. Methods in Cell Biology. 101: 19-38. PMID 21550438 DOI: 10.1016/B978-0-12-387036-0.00002-5  0.359
2011 Paulson V, Chandler G, Rakheja D, Galindo RL, Wilson K, Amatruda JF, Cameron S. High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis. Genes, Chromosomes & Cancer. 50: 397-408. PMID 21412928 DOI: 10.1002/Gcc.20864  0.406
2011 Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L. Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling. Science Signaling. 4: ra4. PMID 21266715 DOI: 10.1126/Scisignal.2001225  0.351
2011 Fustino NJ, Rakheja D, Amatruda JF. BMP signaling activity in pediatric germ cell tumors. Journal of Clinical Oncology. 29: 9538-9538. DOI: 10.1200/Jco.2011.29.15_Suppl.9538  0.407
2011 Poynter JN, Christensen B, Nelson HH, Amatruda JF, Frazier AL, Ross JA. Abstract 872: DNA methylation patterns distinguish histologic subtypes of pediatric germ cell tumors Cancer Research. 71: 872-872. DOI: 10.1158/1538-7445.Am2011-872  0.437
2009 Neumann JC, Dovey JS, Chandler GL, Carbajal L, Amatruda JF. Identification of a heritable model of testicular germ cell tumor in the zebrafish. Zebrafish. 6: 319-27. PMID 20047465 DOI: 10.1089/Zeb.2009.0613  0.48
2009 Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, ... ... Amatruda JF, et al. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Molecular and Cellular Biology. 29: 5911-22. PMID 19704007 DOI: 10.1128/Mcb.00558-09  0.412
2009 Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nature Chemical Biology. 5: 100-7. PMID 19125156 DOI: 10.1038/Nchembio.137  0.324
2009 Leacock SW, Basse AN, Chandler GL, Kirk A, Amatruda JF. Abstract B36: The Ewing's sarcoma fusion oncogene EWS-FLI1 induces tumors and developmental phenotypes in zebrafish Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B36  0.472
2008 Amatruda JF, Patton EE. Genetic models of cancer in zebrafish. International Review of Cell and Molecular Biology. 271: 1-34. PMID 19081540 DOI: 10.1016/S1937-6448(08)01201-X  0.369
2007 Grzmil M, Whiting D, Maule J, Anastasaki C, Amatruda JF, Kelsh RN, Norbury CJ, Patton EE. The INT6 cancer gene and MEK signaling pathways converge during zebrafish development. Plos One. 2: e959. PMID 17895999 DOI: 10.1371/Journal.Pone.0000959  0.403
2007 Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI. A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & Development. 21: 55-9. PMID 17210788 DOI: 10.1101/Gad.1470407  0.391
2007 Amatruda J, Neumann J, Lillard K, Carbajal L. Germline Development And Germ Cell Tumors In The Zebrafish System Biology of Reproduction. 77: 72-72. DOI: 10.1093/Biolreprod/77.S1.72B  0.44
2005 Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature Chemical Biology. 1: 366-70. PMID 16372403 DOI: 10.1038/Nchembio749  0.351
2005 Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 102: 13194-9. PMID 16150706 DOI: 10.1073/Pnas.0506583102  0.405
2005 Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, et al. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current Biology : Cb. 15: 249-54. PMID 15694309 DOI: 10.1016/J.Cub.2005.01.031  0.318
2004 Shepard JL, Stern HM, Pfaff KL, Amatruda JF. Analysis of the cell cycle in zebrafish embryos. Methods in Cell Biology. 76: 109-25. PMID 15602874 DOI: 10.1016/S0091-679X(04)76007-0  0.358
2000 Amatruda JF, Zon LI. Dissecting hematopoiesis and disease using the zebrafish. Developmental Biology. 216: 1-15. PMID 10588859 DOI: 10.1006/Dbio.1999.9462  0.374
1998 Amatruda JF, Tran K, Mantel M, Singer S, Demetri G. Diagnosis in oncology. Askin tumor. Journal of Clinical Oncology. 16: 1997-1998. PMID 9586920 DOI: 10.1200/Jco.1998.16.5.1997  0.359
1992 Amatruda JF, Cooper JA. Purification, characterization, and immunofluorescence localization of Saccharomyces cerevisiae capping protein. The Journal of Cell Biology. 117: 1067-76. PMID 1315784 DOI: 10.1083/Jcb.117.5.1067  0.449
1991 Cooper JA, Caldwell JE, Gattermeir DJ, Torres MA, Amatruda JF, Casella JF. Variant cDNAs encoding proteins similar to the α subunit of chicken CapZ Cell Motility and the Cytoskeleton. 18: 204-214. PMID 1711931 DOI: 10.1002/Cm.970180306  0.434
1990 Amatruda JF, Cannon JF, Tatchell K, Hug C, Cooper JA. Disruption of the actin cytoskeleton in yeast capping protein mutants. Nature. 344: 352-4. PMID 2179733 DOI: 10.1038/344352A0  0.495
Low-probability matches (unlikely to be authored by this person)
2017 Poynter JN, Richardson M, Roesler M, Krailo M, Amatruda JF, Frazier AL. Family history of cancer in children and adolescents with germ cell tumours: a report from the Children's Oncology Group. British Journal of Cancer. PMID 29065103 DOI: 10.1038/Bjc.2017.358  0.299
2020 Badia RR, Abe D, Wong D, Singla N, Savelyeva A, Chertack N, Woldu SL, Lotan Y, Mauck R, Ouyang D, Meng X, Lewis CM, Majmudar K, Jia L, Kapur P, ... ... Amatruda JF, et al. Real-World Application of Pre-orchiectomy miR-371a-3p Test in Testicular Germ Cell Tumor Management. The Journal of Urology. 101097JU000000000000. PMID 32856980 DOI: 10.1097/Ju.0000000000001337  0.299
2018 Williams LA, Mills L, Hooten AJ, Langer E, Roesler M, Frazier AL, Krailo M, Nelson HH, Bestrashniy J, Amatruda JF, Poynter JN. Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. British Journal of Cancer. PMID 30287918 DOI: 10.1038/S41416-018-0277-5  0.298
2019 O'Neill AF, Xia C, Krailo MD, Shaikh F, Pashankar FD, Billmire DF, Olson TA, Amatruda JF, Villaluna D, Huang L, Malogolowkin M, Rodriguez-Galindo C, Frazier AL. α-Fetoprotein as a predictor of outcome for children with germ cell tumors: A report from the Malignant Germ Cell International Consortium. Cancer. PMID 31355926 DOI: 10.1002/Cncr.32363  0.298
2009 Lu WJ, Amatruda JF, Abrams JM. p53 ancestry: gazing through an evolutionary lens. Nature Reviews. Cancer. 9: 758-62. PMID 19776745 DOI: 10.1038/Nrc2732  0.296
2002 Amatruda JF, Shepard JL, Stern HM, Zon LI. Zebrafish as a cancer model system. Cancer Cell. 1: 229-31. PMID 12086858 DOI: 10.1016/S1535-6108(02)00052-1  0.295
2012 Hajeri VA, Amatruda JF. Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms. Disease Models & Mechanisms. 5: 33-7. PMID 22107871 DOI: 10.1242/Dmm.007989  0.291
2017 Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L. Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist. Proceedings of the National Academy of Sciences of the United States of America. PMID 28143939 DOI: 10.1073/Pnas.1621346114  0.291
2020 Shaikh F, Stark D, Fonseca A, Dang H, Xia C, Krailo M, Pashankar F, Rodriguez-Galindo C, Olson TA, Nicholson JC, Murray MJ, Amatruda JF, Billmire D, Stoneham S, Frazier AL. Outcomes of adolescent males with extracranial metastatic germ cell tumors: A report from the Malignant Germ Cell Tumor International Consortium. Cancer. PMID 33079404 DOI: 10.1002/cncr.33273  0.287
2018 Bhakta M, Padanad MS, Harris JP, Lubczyk C, Amatruda JF, Munshi NV. pouC regulates expression of bmp4 during atrioventricular canal formation in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 30444277 DOI: 10.1002/Dvdy.2  0.286
2010 Poynter JN, Amatruda JF, Ross JA. Trends in incidence and survival of pediatric and adolescent patients with germ cell tumors in the United States, 1975 to 2006. Cancer. 116: 4882-91. PMID 20597129 DOI: 10.1002/Cncr.25454  0.282
2020 Bagrodia A, Daneshmand S, Cheng L, Amatruda J, Murray M, Lafin JT. The Past and Future of Biomarkers in Testicular Germ Cell Tumors SociéTé Internationale D’Urologie Journal. 1: 77-84. DOI: 10.48083/RZEQ2256  0.279
2014 Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell. 157: 565-79. PMID 24766806 DOI: 10.1016/J.Cell.2014.03.032  0.278
2022 Segal D, Mazloom-Farsibaf H, Chang BJ, Roudot P, Rajendran D, Daetwyler S, Fiolka R, Warren M, Amatruda JF, Danuser G. In vivo 3D profiling of site-specific human cancer cell morphotypes in zebrafish. The Journal of Cell Biology. 221. PMID 36155740 DOI: 10.1083/jcb.202109100  0.274
2016 Moon J, Amatruda JF. Biochemical Analysis of Tankyrase Activity in Zebrafish In Vitro and In Vivo. Methods in Molecular Biology (Clifton, N.J.). 1481: 95-100. PMID 27590155 DOI: 10.1007/978-1-4939-6393-5_10  0.273
2014 Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, et al. Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743)) Cell. 157. DOI: 10.1016/J.Cell.2014.05.008  0.273
2022 Singla N, Wong J, Singla S, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda JF, Lindsay Frazier A, Bagrodia A. Clinicopathologic predictors of outcomes in children with stage I testicular germ cell tumors: A pooled post hoc analysis of trials from the Children's Oncology Group. Journal of Pediatric Urology. PMID 35606324 DOI: 10.1016/j.jpurol.2022.04.022  0.272
1999 FIORANI P., AMATRUDA JF, SILVESTRI, BJORNSTI MA, BUTLER RH, BENEDETTI P.. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity Molecular Pharmacology. pp. 1105-1115 I. DOI: 10.1124/Mol.56.6.1105  0.271
2014 Patton EE, Dhillon P, Amatruda JF, Ramakrishnan L. Spotlight on zebrafish: translational impact. Disease Models & Mechanisms. 7: 731-3. PMID 24973741 DOI: 10.1242/Dev.114744  0.269
2009 Lu J, Ma Z, Hsieh JC, Fan CW, Chen B, Longgood JC, Williams NS, Amatruda JF, Lum L, Chen C. Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorganic & Medicinal Chemistry Letters. 19: 3825-7. PMID 19410457 DOI: 10.1016/J.Bmcl.2009.04.040  0.268
2010 Mitchell IC, Brown TS, Terada LS, Amatruda JF, Nwariaku FE. Effect of vascular cadherin knockdown on zebrafish vasculature during development. Plos One. 5: e8807. PMID 20098718 DOI: 10.1371/Journal.Pone.0008807  0.268
2018 Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. Author response: PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis Elife. DOI: 10.7554/Elife.33800.032  0.267
2012 Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN. C/EBP transcription factors mediate epicardial activation during heart development and injury. Science (New York, N.Y.). 338: 1599-603. PMID 23160954 DOI: 10.1126/Science.1229765  0.267
2020 Kenigsberg AP, Lafin JT, Meng X, Abe D, Savalyeva A, Singla N, Woldu SL, Lotan Y, Kapur P, Margulis V, Amatruda JF, Bagrodia A. Predictive capacity of miRNA-375 in identifying teratoma in post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND). Journal of Clinical Oncology. 38: 416-416. DOI: 10.1200/Jco.2020.38.6_Suppl.416  0.266
2021 Skowron MA, Oing C, Bremmer F, Ströbel P, Murray MJ, Coleman N, Amatruda JF, Honecker F, Bokemeyer C, Albers P, Nettersheim D. The developmental origin of cancers defines basic principles of cisplatin resistance. Cancer Letters. 519: 199-210. PMID 34320371 DOI: 10.1016/j.canlet.2021.07.037  0.262
2014 Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nature Communications. 2: 4802. PMID 25190313 DOI: 10.1038/Ncomms5802  0.261
2013 Wang X, Moon J, Dodge ME, Pan X, Zhang L, Hanson JM, Tuladhar R, Ma Z, Shi H, Williams NS, Amatruda JF, Carroll TJ, Lum L, Chen C. The development of highly potent inhibitors for porcupine. Journal of Medicinal Chemistry. 56: 2700-4. PMID 23477365 DOI: 10.1021/Jm400159C  0.26
2021 Lafin JT, Murray MJ, Coleman N, Frazier AL, Amatruda JF, Bagrodia A. The Road Ahead for Circulating microRNAs in Diagnosis and Management of Testicular Germ Cell Tumors. Molecular Diagnosis & Therapy. PMID 33893623 DOI: 10.1007/s40291-021-00526-6  0.252
2020 Singla S, Wong J, Singla N, Krailo MD, Huang L, Shaikh F, Billmire DF, Rescorla FJ, Ross JH, Dicken BJ, Amatruda JF, Frazier AL, Bagrodia A. Clinicopathologic predictors of outcomes in children with stage I germ cell tumors: A pooled post hoc analysis of trials from the Children’s Oncology Group. Journal of Clinical Oncology. 38: 418-418. DOI: 10.1200/jco.2020.38.6_suppl.418  0.251
2021 Lafin JT, Amatruda JF, Bagrodia A. Correction to: Germ Cell Tumor Cell Culture Techniques. Methods in Molecular Biology (Clifton, N.J.). 2195: C1. PMID 34453282 DOI: 10.1007/978-1-0716-0860-9_18  0.25
2021 Shah R, Weil BR, Weldon CB, Amatruda JF, Frazier AL. Neonatal Malignant Disorders: Germ Cell Tumors. Clinics in Perinatology. 48: 147-165. PMID 33583501 DOI: 10.1016/j.clp.2020.11.010  0.249
2008 Mitchell IC, Amatruda JF, Nwariaku FE. 149. Zebrafish VE Cadherin Knockdown: An In Vivo Model for Endothelial Biology Journal of Surgical Research. 144: 242-243. DOI: 10.1016/J.Jss.2007.12.169  0.248
2022 Cidre-Aranaz F, Watson S, Amatruda JF, Nakamura T, Delattre O, de Alava E, Dirksen U, Grünewald TGP. Small round cell sarcomas. Nature Reviews. Disease Primers. 8: 66. PMID 36202860 DOI: 10.1038/s41572-022-00393-3  0.247
2010 Pon L, Amatruda JF. Breast cancer between faith and medicine: the Peres Maldonado ex-voto. Medical Humanities. 36: 112-4. PMID 21393294 DOI: 10.1136/Jmh.2010.005587  0.245
2022 Yang A, Patterson A, Pavlock T, Chen KS, Gagan J, Hatley ME, Frazier AL, Amatruda JF, Laetsch TW, Rakheja D. Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial. Pediatric Blood & Cancer. 69: e29451. PMID 34866303 DOI: 10.1002/pbc.29451  0.244
2017 Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Erratum: Publisher Correction: Somatic mutations in and impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nature Communications. 8: 16177. PMID 31305780 DOI: 10.1038/Ncomms16177  0.244
2023 Christodoulou E, Yellapantula V, O'Halloran K, Xu L, Berry JL, Cotter JA, Zdanowicz A, Mascarenhas L, Amatruda JF, Ostrow D, Bootwalla M, Gai X, Navid F, Biegel JA. Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors. Npj Precision Oncology. 7: 21. PMID 36805676 DOI: 10.1038/s41698-023-00357-0  0.242
2021 Lafin JT, Amatruda JF, Bagrodia A. Germ Cell Tumor Cell Culture Techniques. Methods in Molecular Biology (Clifton, N.J.). 2195: 65-76. PMID 32852757 DOI: 10.1007/978-1-0716-0860-9_5  0.232
2018 Chen KS, Stuart SH, Stroup EK, Shukla AS, Wang J, Rajaram V, Vujanic GM, Slone T, Rakheja D, Amatruda JF. Distinct Hotspot Mutations Identify Bilateral Tumors as Separate Events. Jco Precision Oncology. 2. PMID 31893257 DOI: 10.1200/PO.17.00113  0.23
2021 Amatruda JF. Modeling the developmental origins of pediatric cancer to improve patient outcomes. Disease Models & Mechanisms. 14. PMID 33619212 DOI: 10.1242/dmm.048930  0.229
2022 Singla N, Wong J, Singla S, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda JF, Frazier AL, Bagrodia A. Response to commentary re: Clinicopathologic predictors of outcomes in children with stage I testicular germ cell tumors: A pooled post hoc analysis of trials from the Children's oncology group. Journal of Pediatric Urology. PMID 35868999 DOI: 10.1016/j.jpurol.2022.06.027  0.222
2019 Frazier AL, Krailo M, Amatruda J, Murray M, Lopes L, Faure-Conter C, Stoneham S, Pashankar F, Shaikh F, Chinnaswamy G, Xie Y, Gershenson D, Covens A, Olson T, Klosterkemper L, et al. The Malignant Germ Cell International Consortium (MaGIC) European Urology Supplements. 18: 6. DOI: 10.1016/S1569-9056(19)32470-4  0.217
2018 Woldu SL, Moore JA, Ci B, Freifeld Y, Clinton TN, Aydin AM, Singla N, Laura-Maria K, Hutchinson RC, Amatruda JF, Sagalowsky A, Lotan Y, Arriaga Y, Margulis V, Xie Y, et al. Practice Patterns and Impact of Postchemotherapy Retroperitoneal Lymph Node Dissection on Testicular Cancer Outcomes. European Urology Oncology. 1: 242-251. PMID 31058267 DOI: 10.1016/J.Euo.2018.04.005  0.206
2020 Ci B, Yang DM, Krailo M, Xia C, Yao B, Luo D, Zhou Q, Xiao G, Xu L, Skapek SX, Murray MM, Amatruda JF, Klosterkemper L, Shaikh F, Faure-Conter C, et al. Development of a Data Model and Data Commons for Germ Cell Tumors. Jco Clinical Cancer Informatics. 4: 555-566. PMID 32568554 DOI: 10.1200/CCI.20.00025  0.204
2022 Fonseca A, Lobo J, Hazard FK, Gell J, Nicholls PK, Weiss RS, Klosterkemper L, Volchenboum SL, Nicholson JC, Frazier AL, Amatruda JF, Bagrodia A, Lockley M, Murray MJ. Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium. British Journal of Cancer. PMID 36229581 DOI: 10.1038/s41416-022-02000-4  0.203
2020 Kenigsberg* A, Lafin J, Meng X, Abe D, Savalyeva A, Singla N, Woldu S, Lotan Y, Kapur P, Margulis V, Amatruda J, Bagrodia A. PD19-09 PREDICTIVE CAPACITY OF MIRNA-375 IN IDENTIFYING TERATOMA IN POST-CHEMOTHERAPY RETROPERITONEAL LYMPH NODE DISSECTION (PC-RPLND) The Journal of Urology. 203: e385. DOI: 10.1097/Ju.0000000000000862.09  0.201
2019 Shaikh F, Stark D, Dang H, Xia C, Krailo M, Stenning S, Pashankar F, Rodriguez-Galindo C, Olson T, Depani S, Stoneham S, Nicholson J, Murray M, Amatruda J, Billmire D, et al. Outcomes of adolescent males with extracranial metastatic germ cell tumours compared with children and young adults: A report from the Malignant Germ Cell Tumour International Consortium (MaGIC) group European Urology Supplements. 18: 9. DOI: 10.1016/S1569-9056(19)32477-7  0.199
2019 O’Neill AF, Xia C, Krailo MD, Shaikh F, Mrcp FDPM, Billmire DF, Olson TA, Amatruda JF, Ms DV, Huang L, Malogolowkin M, Rodriguez-Galindo C, Frazier AL. Alpha-fetoprotein (AFP) as a predictor of outcome for children with germ cell tumours: A report from the Malignant Germ Cell International Consortium (MaGIC) European Urology Supplements. 18: 19. DOI: 10.1016/S1569-9056(19)32507-2  0.189
2021 Su XA, Ma D, Parsons JV, Replogle JM, Amatruda JF, Whittaker CA, Stegmaier K, Amon A. is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress. Genes & Development. PMID 33766983 DOI: 10.1101/gad.345454.120  0.185
2018 Stroup EK, Yeu Y, Budhipramono A, Hwang TH, Rakheja D, Erdreich‐Epstein A, Laetsch TW, Amatruda JF, Chen KS. WT‐CLS1 is a rhabdoid tumor cell line and can be inhibited by miR ‐16 Cancer Reports. 2. DOI: 10.1002/CNR2.1110  0.183
2008 Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R, Pascual J, Imamura S, Kishi S, Amatruda JF, Kanki JP, Green DR, D'Andrea AA, Look AT. Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell. 133: 864-77. PMID 18510930 DOI: 10.1016/j.cell.2008.03.037  0.179
2022 Konneh B, Lafin JT, Howard J, Gerald T, Amini A, Savelyeva A, Woldu SL, Lewis CM, Jia L, Margulis V, Coleman N, Scarpini C, Frazier AL, Murray MJ, Amatruda JF, et al. Evaluation of miR-371a-3p to predict viable germ cell tumor in patients with pure seminoma receiving retroperitoneal lymph node dissection. Andrology. PMID 36254623 DOI: 10.1111/andr.13317  0.169
2019 Xu L, Pierce J, Sanchez A, Chen K, Shukla A, Fustino N, Stuart S, Bagrodia A, Krailo M, Shaikh F, Billmire D, Pashankar F, Bestrashniy J, Wolter Oosterhuis J, Biermann K, ... ... Amatruda J, et al. Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumours of childhood and adolescence European Urology Supplements. 18: 13-14. DOI: 10.1016/S1569-9056(19)32491-1  0.169
2021 Zöllner SK, Amatruda JF, Bauer S, Collaud S, de Álava E, DuBois SG, Hardes J, Hartmann W, Kovar H, Metzler M, Shulman DS, Streitbürger A, Timmermann B, Toretsky JA, Uhlenbruch Y, et al. Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives. Journal of Clinical Medicine. 10. PMID 33919988 DOI: 10.3390/jcm10081685  0.168
2023 Hatton JN, Frone MN, Cox HC, Crowley SB, Hiraki S, Yokoyama NN, Abul-Husn NS, Amatruda JF, Anderson MJ, Bofill-De Ros X, Carr AG, Chao EC, Chen KS, Gu S, Higgs C, et al. Specifications of the ACMG/AMP Variant Classification Guidelines for Germline Variant Curation. Human Mutation. 2023. PMID 38084291 DOI: 10.1155/2023/9537832  0.16
2020 Bagrodia A, Savelyeva A, Lafin JT, Speir RW, Chesnut GT, Frazier AL, Woldu SL, Margulis V, Murray MJ, Amatruda JF, Lotan Y. Impact of Circulating miRNA-371a-3p Test on Appropriateness of Treatment and Cost Outcomes in Patients with Stage I Nonseminomatous Germ Cell Tumors. Bju International. PMID 33124175 DOI: 10.1111/bju.15288  0.143
2019 Frazier AL, Faure-Conter C, Fresneau B, Lopes LF, Pashankar F, Shaikh F, O’Neill AF, Amatruda JF, Krailo M, Klosterkemper L, Piao J, Dang H, Xia C, Stoneham S, Murray MJ, et al. Validation of the MaGIC paediatric germ cell tumour risk stratification European Urology Supplements. 18: 20. DOI: 10.1016/S1569-9056(19)32509-6  0.134
2021 Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, ... ... Amatruda JF, et al. Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force. Journal of Clinical Medicine. 10. PMID 33915882 DOI: 10.3390/jcm10071416  0.123
2021 Piao J, Lafin JT, Scarpini CG, Nuño MM, Syring I, Dieckmann KP, Belge G, Ellinger J, Amatruda JF, Bagrodia A, Coleman N, Krailo MD, Frazier AL, Murray MJ. A Multi-institutional Pooled Analysis Demonstrates That Circulating miR-371a-3p Alone is Sufficient for Testicular Malignant Germ Cell Tumor Diagnosis. Clinical Genitourinary Cancer. PMID 34629299 DOI: 10.1016/j.clgc.2021.08.006  0.118
2023 Lafin JT, Scarpini CG, Amini A, Konneh B, Howard JM, Gerald T, Nuno M, Piao J, Savelyeva A, Wang Z, Gagan J, Jia L, Lewis CM, Murray S, Sawa YC, ... ... Amatruda JF, et al. Refining the serum miR-371a-3p test for viable germ cell tumor detection. Scientific Reports. 13: 10558. PMID 37386046 DOI: 10.1038/s41598-023-37271-1  0.093
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2023 Lafin J, Scarpini C, Amini A, Konneh B, Howard J, Gerald T, Nuno M, Piao J, Savelyeva A, Wang Z, Gagan J, Jia L, Lewis C, Murray S, Sawa Y, ... ... Amatruda J, et al. Refining the serum miR-371a-3p test for viable germ cell tumor detection: identification and definition of an indeterminate range. Research Square. PMID 36993198 DOI: 10.21203/rs.3.rs-2644890/v1  0.076
2020 Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, ... ... Amatruda JF, et al. Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. Nature Communications. 11: 6068. PMID 33230121 DOI: 10.1038/s41467-020-20017-2  0.069
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2023 Amatruda JF. Building advocacy into research. Disease Models & Mechanisms. 16. PMID 38108236 DOI: 10.1242/dmm.050646  0.022
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