Year |
Citation |
Score |
2023 |
Settembre C, Perera RM. Lysosomes as coordinators of cellular catabolism, metabolic signalling and organ physiology. Nature Reviews. Molecular Cell Biology. PMID 38001393 DOI: 10.1038/s41580-023-00676-x |
0.338 |
|
2023 |
Singh P, Gollapalli K, Mangiola S, Schranner D, Yusuf MA, Chamoli M, Shi SL, Lopes Bastos B, Nair T, Riermeier A, Vayndorf EM, Wu JZ, Nilakhe A, Nguyen CQ, Muir M, ... ... Settembre C, et al. Taurine deficiency as a driver of aging. Science (New York, N.Y.). 380: eabn9257. PMID 37289866 DOI: 10.1126/science.abn9257 |
0.502 |
|
2021 |
Morleo M, Brillante S, Formisano U, Ferrante L, Carbone F, Iaconis D, Palma A, Buonomo V, Maione AS, Grumati P, Settembre C, Franco B. Regulation of autophagosome biogenesis by OFD1-mediated selective autophagy. The Embo Journal. 40: e105120. PMID 33368531 DOI: 10.15252/embj.2020105120 |
0.312 |
|
2020 |
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, ... ... Settembre C, et al. MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. The Embo Journal. e105696. PMID 32716134 DOI: 10.15252/Embj.2020105696 |
0.473 |
|
2020 |
Pastore N, Huynh T, Herz NJ, Calcagni' A, Klisch TJ, Brunetti L, Kim KH, De Giorgi M, Hurley A, Carissimo A, Mutarelli M, Aleksieva N, D'Orsi L, Lagor WR, Moore DD, ... Settembre C, et al. TFEB regulates murine liver cell fate during development and regeneration. Nature Communications. 11: 2461. PMID 32424153 DOI: 10.1038/S41467-020-16300-X |
0.354 |
|
2019 |
Di Malta C, Cinque L, Settembre C. Transcriptional Regulation of Autophagy: Mechanisms and Diseases. Frontiers in Cell and Developmental Biology. 7: 114. PMID 31312633 DOI: 10.3389/fcell.2019.00114 |
0.315 |
|
2019 |
Glatigny M, Moriceau S, Rivagorda M, Ramos-Brossier M, Nascimbeni AC, Lante F, Shanley MR, Boudarene N, Rousseaud A, Friedman AK, Settembre C, Kuperwasser N, Friedlander G, Buisson A, Morel E, et al. Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline. Current Biology : Cb. PMID 30661803 DOI: 10.1016/J.Cub.2018.12.021 |
0.322 |
|
2018 |
Doronzo G, Astanina E, Corà D, Chiabotto G, Comunanza V, Noghero A, Neri F, Puliafito A, Primo L, Spampanato C, Settembre C, Ballabio A, Camussi G, Oliviero S, Bussolino F. TFEB controls vascular development by regulating the proliferation of endothelial cells. The Embo Journal. PMID 30591554 DOI: 10.15252/Embj.201798250 |
0.369 |
|
2018 |
Settembre C, Cinque L, Bartolomeo R, Di Malta C, De Leonibus C, Forrester A. Defective collagen proteostasis and matrix formation in the pathogenesis of lysosomal storage disorders. Matrix Biology : Journal of the International Society For Matrix Biology. 71: 283-293. PMID 29870768 DOI: 10.1016/J.Matbio.2018.06.001 |
0.42 |
|
2017 |
Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano AC, Monfregola J, De Gennaro E, Nusco E, Azario I, Lanzara C, Serafini M, Levine B, Ballabio A, Settembre C. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. The Journal of Clinical Investigation. PMID 28872463 DOI: 10.1172/Jci94130 |
0.351 |
|
2017 |
Sha Y, Rao L, Settembre C, Ballabio A, Eissa NT. STUB1 regulates TFEB-induced autophagy-lysosome pathway. The Embo Journal. PMID 28754656 DOI: 10.15252/Embj.201796699 |
0.46 |
|
2017 |
Di Malta C, Siciliano D, Calcagni A, Monfregola J, Punzi S, Pastore N, Eastes AN, Davis O, De Cegli R, Zampelli A, Di Giovannantonio LG, Nusco E, Platt N, Guida A, Ogmundsdottir MH, ... ... Settembre C, et al. Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth. Science (New York, N.Y.). 356: 1188-1192. PMID 28619945 DOI: 10.1126/Science.Aag2553 |
0.424 |
|
2017 |
Medina DL, Settembre C, Ballabio A. Methods to Monitor and Manipulate TFEB Activity During Autophagy. Methods in Enzymology. 588: 61-78. PMID 28237119 DOI: 10.1016/bs.mie.2016.10.008 |
0.358 |
|
2016 |
Zito E, Buono M, Pepe S, Settembre C, Annunziata I, Surace EM, Dierks T, Monti M, Cozzolino M, Pucci P, Ballabio A, Cosma MP. Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum. The Embo Journal. 35: 2614-2615. PMID 27908960 DOI: 10.15252/Embj.201670020 |
0.309 |
|
2016 |
Calcagnì A, Kors L, Verschuren E, De Cegli R, Zampelli N, Nusco E, Confalonieri S, Bertalot G, Pece S, Settembre C, Malouf GG, Leemans JC, de Heer E, Salvatore M, Peters DJ, et al. Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling. Elife. 5. PMID 27668431 DOI: 10.7554/Elife.17047 |
0.328 |
|
2016 |
Fraldi A, Klein AD, Medina DL, Settembre C. Brain Disorders Due to Lysomal Dysfunction. Annual Review of Neuroscience. PMID 27090953 DOI: 10.1146/Annurev-Neuro-070815-014031 |
0.386 |
|
2016 |
Cinque L, Forrester A, Settembre C. Autophagy gets to the bone. Cell Cycle (Georgetown, Tex.). 15: 871-2. PMID 26939858 DOI: 10.1080/15384101.2016.1151724 |
0.321 |
|
2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Settembre C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.35 |
|
2015 |
Cinque L, Forrester A, Bartolomeo R, Svelto M, Venditti R, Montefusco S, Polishchuk E, Nusco E, Rossi A, Medina DL, Polishchuk R, De Matteis MA, Settembre C. FGF signalling regulates bone growth through autophagy. Nature. PMID 26595272 DOI: 10.1038/Nature16063 |
0.433 |
|
2015 |
Medina DL, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, Montefusco S, Scotto-Rosato A, Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB. Nature Cell Biology. 17: 288-99. PMID 25720963 DOI: 10.1038/Ncb3114 |
0.441 |
|
2015 |
Goginashvili A, Zhang Z, Erbs E, Spiegelhalter C, Kessler P, Mihlan M, Pasquier A, Krupina K, Schieber N, Cinque L, Morvan J, Sumara I, Schwab Y, Settembre C, Ricci R. Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells. Science (New York, N.Y.). 347: 878-82. PMID 25700520 DOI: 10.1126/Science.Aaa2628 |
0.337 |
|
2015 |
Settembre C, Medina DL. TFEB and the CLEAR network. Methods in Cell Biology. 126: 45-62. PMID 25665440 DOI: 10.1016/Bs.Mcb.2014.11.011 |
0.425 |
|
2015 |
Caiazzo M, Giannelli S, Valente P, Lignani G, Carissimo A, Sessa A, Colasante G, Bartolomeo R, Massimino L, Ferroni S, Settembre C, Benfenati F, Broccoli V. Direct conversion of fibroblasts into functional astrocytes by defined transcription factors. Stem Cell Reports. 4: 25-36. PMID 25556566 DOI: 10.1016/J.Stemcr.2014.12.002 |
0.344 |
|
2014 |
Settembre C, Ballabio A. Cell metabolism: autophagy transcribed. Nature. 516: 40-1. PMID 25383529 DOI: 10.1038/Nature13939 |
0.375 |
|
2014 |
Settembre C, Ballabio A. Lysosome: regulator of lipid degradation pathways. Trends in Cell Biology. 24: 743-50. PMID 25061009 DOI: 10.1016/J.Tcb.2014.06.006 |
0.428 |
|
2014 |
Emanuel R, Sergin I, Bhattacharya S, Turner JN, Epelman S, Settembre C, Diwan A, Ballabio A, Razani B. Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1942-52. PMID 25060788 DOI: 10.1161/Atvbaha.114.303342 |
0.336 |
|
2014 |
Settembre C, Ballabio A. Lysosomal adaptation: how the lysosome responds to external cues. Cold Spring Harbor Perspectives in Biology. 6. PMID 24799353 DOI: 10.1101/Cshperspect.A016907 |
0.417 |
|
2014 |
Shapiro IM, Layfield R, Lotz M, Settembre C, Whitehouse C. Boning up on autophagy: the role of autophagy in skeletal biology. Autophagy. 10: 7-19. PMID 24225636 DOI: 10.4161/Auto.26679 |
0.362 |
|
2013 |
Settembre C, Ballabio A. New targets for old diseases: lessons from mucolipidosis type II. Embo Molecular Medicine. 5: 1801-3. PMID 24293315 DOI: 10.1002/Emmm.201303496 |
0.37 |
|
2013 |
Settembre C, Fraldi A, Medina DL, Ballabio A. Signals from the lysosome: a control centre for cellular clearance and energy metabolism. Nature Reviews. Molecular Cell Biology. 14: 283-96. PMID 23609508 DOI: 10.1038/Nrm3565 |
0.43 |
|
2013 |
Settembre C, De Cegli R, Mansueto G, Saha PK, Vetrini F, Visvikis O, Huynh T, Carissimo A, Palmer D, Klisch TJ, Wollenberg AC, Di Bernardo D, Chan L, Irazoqui JE, Ballabio A. TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop. Nature Cell Biology. 15: 647-58. PMID 23604321 DOI: 10.1038/Ncb2718 |
0.387 |
|
2013 |
Ferron M, Settembre C, Shimazu J, Lacombe J, Kato S, Rawlings DJ, Ballabio A, Karsenty G. A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts. Genes & Development. 27: 955-69. PMID 23599343 DOI: 10.1101/Gad.213827.113 |
0.698 |
|
2012 |
Di Malta C, Fryer JD, Settembre C, Ballabio A. Autophagy in astrocytes: a novel culprit in lysosomal storage disorders. Autophagy. 8: 1871-2. PMID 23047468 DOI: 10.4161/Auto.22184 |
0.3 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Settembre C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.316 |
|
2012 |
Di Malta C, Fryer JD, Settembre C, Ballabio A. Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder. Proceedings of the National Academy of Sciences of the United States of America. 109: E2334-42. PMID 22826245 DOI: 10.1073/Pnas.1209577109 |
0.31 |
|
2012 |
Arteaga-Solis E, Settembre C, Ballabio A, Karsenty G. Sulfatases are determinants of alveolar formation. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 253-60. PMID 22366163 DOI: 10.1016/J.Matbio.2012.02.001 |
0.521 |
|
2012 |
Settembre C, Zoncu R, Medina DL, Vetrini F, Erdin S, Erdin S, Huynh T, Ferron M, Karsenty G, Vellard MC, Facchinetti V, Sabatini DM, Ballabio A. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. The Embo Journal. 31: 1095-108. PMID 22343943 DOI: 10.1038/Emboj.2012.32 |
0.697 |
|
2012 |
Zee T, Settembre C, Levine RL, Karsenty G. T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts. Molecular and Cellular Biology. 32: 1080-8. PMID 22252315 DOI: 10.1128/Mcb.06279-11 |
0.68 |
|
2011 |
Settembre C, Ballabio A. TFEB regulates autophagy: an integrated coordination of cellular degradation and recycling processes. Autophagy. 7: 1379-81. PMID 21785263 DOI: 10.4161/Auto.7.11.17166 |
0.415 |
|
2011 |
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A. TFEB links autophagy to lysosomal biogenesis. Science (New York, N.Y.). 332: 1429-33. PMID 21617040 DOI: 10.1126/Science.1204592 |
0.471 |
|
2011 |
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina DL, Settembre C, Gavina M, Raia V, Ballabio A, Maiuri L. Cystic fibrosis: a disorder with defective autophagy. Autophagy. 7: 104-6. PMID 21048426 DOI: 10.4161/Auto.7.1.13987 |
0.308 |
|
2010 |
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, et al. Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nature Cell Biology. 12: 863-75. PMID 20711182 DOI: 10.1038/Ncb2090 |
0.358 |
|
2009 |
Karsenty G, Kronenberg HM, Settembre C. Genetic control of bone formation. Annual Review of Cell and Developmental Biology. 25: 629-48. PMID 19575648 DOI: 10.1146/Annurev.Cellbio.042308.113308 |
0.471 |
|
2009 |
Settembre C, Arteaga-Solis E, Ballabio A, Karsenty G. Self-eating in skeletal development: implications for lysosomal storage disorders. Autophagy. 5: 228-9. PMID 19029806 DOI: 10.4161/Auto.5.2.7390 |
0.53 |
|
2008 |
Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G. Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes & Development. 22: 2645-50. PMID 18832069 DOI: 10.1101/Gad.1711308 |
0.572 |
|
2008 |
Settembre C, Fraldi A, Rubinsztein DC, Ballabio A. Lysosomal storage diseases as disorders of autophagy. Autophagy. 4: 113-4. PMID 18000397 DOI: 10.4161/Auto.5227 |
0.352 |
|
2008 |
Settembre C, Fraldi A, Jahreiss L, Spampanato C, Venturi C, Medina D, de Pablo R, Tacchetti C, Rubinsztein DC, Ballabio A. A block of autophagy in lysosomal storage disorders. Human Molecular Genetics. 17: 119-29. PMID 17913701 DOI: 10.1093/Hmg/Ddm289 |
0.381 |
|
2008 |
Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Awqati QA, Ballabio A, Karsenty G. Proteoglycan desulfation regulates endochondral ossification Matrix Biology. 27: 37. DOI: 10.1016/J.Matbio.2008.09.330 |
0.558 |
|
2007 |
Annunziata I, Bouchè V, Lombardi A, Settembre C, Ballabio A. Multiple sulfatase deficiency is due to hypomorphic mutations of the SUMF1 gene. Human Mutation. 28: 928. PMID 17657823 DOI: 10.1002/Humu.9504 |
0.335 |
|
2007 |
Zito E, Buono M, Pepe S, Settembre C, Annunziata I, Surace EM, Dierks T, Monti M, Cozzolino M, Pucci P, Ballabio A, Cosma MP. Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum. The Embo Journal. 26: 2443-53. PMID 17446859 DOI: 10.1038/Sj.Emboj.7601695 |
0.357 |
|
2007 |
Settembre C, Annunziata I, Spampanato C, Zarcone D, Cobellis G, Nusco E, Zito E, Tacchetti C, Cosma MP, Ballabio A. Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency. Proceedings of the National Academy of Sciences of the United States of America. 104: 4506-11. PMID 17360554 DOI: 10.1073/Pnas.0700382104 |
0.372 |
|
2007 |
Fraldi A, Biffi A, Lombardi A, Visigalli I, Pepe S, Settembre C, Nusco E, Auricchio A, Naldini L, Ballabio A, Cosma MP. SUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies. The Biochemical Journal. 403: 305-12. PMID 17206939 DOI: 10.1042/Bj20061783 |
0.365 |
|
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